| Primary | ||||||||||||
| Date | # | Opp | Score | Inn | Starter | T | W/L | Save | Versus | T | ||
| 3/1/2008 | @ | GEO | L | 0-7 | Matsuzaka | R | Matsuzaka | Hudson,T | R | |||
| 3/2/2008 | @ | BON | L | 2-3 | Wakefield | R | Wakefield | Santana,E | R | |||
| 3/4/2008 | @ | Pal | L | 1-4 | Weaver | R | Weaver | Maddux | R | |||
| 3/5/2008 | @ | LON | L | 2-11 | Bush | R | Bush | Volquez | R | |||
| 3/6/2008 | CCL | W | 9-3 | Lilly | L | Lilly | Marquis | R | ||||
| 3/7/2008 | MAD | W | 9-4 | Matsuzaka | R | Matsuzaka | Maholm | L | ||||
| 3/8/2008 | Pal | W | 11-4 | Wakefield | R | Wakefield | Beckett | R | ||||
| 3/9/2008 | LON | W | 8-5 | Weaver | R | Weaver | Shouse | Cain | R | |||
| 3/10/2008 | @ | CCL | L | 3-5 | Bush | R | Bush | Nolasco | R | |||
| 3/11/2008 | @ | MAD | W | 7-2 | Lilly | L | Lilly | Sanchez,J | L | |||
| 3/12/2008 | @ | TON | W | 6-4 | Matsuzaka | R | Matsuzaka | Jenks | Webb | R | ||
| 3/13/2008 | @ | WIZ | W | 7-6 | Wakefield | R | Wakefield | Lopez,Ja | Lincecum | R | ||
| 3/14/2008 | BT | L | 6-7 | Weaver | R | Rhodes | McClung | R | ||||
| 3/15/2008 | MUL | W | 9-2 | Bush | R | Bush | De La Rosa | L | ||||
| 3/16/2008 | TON | W | 5-4 | 10 | Lilly | L | Masterson | Billingsley | R | |||
| 3/17/2008 | WIZ | L | 1-11 | Matsuzaka | R | Matsuzaka | Campillo | R | ||||
| 3/18/2008 | @ | BT | W | 6-5 | Wakefield | R | Lopez,Ja | Jenks | Maine | R | ||
| 3/19/2008 | @ | MUL | L | 7-8 | 11 | Weaver | R | Rhodes | Sampson | R | ||
| 3/20/2008 | @ | EDG | W | 7-4 | Bush | R | Bush | Rodney | Litsch | R | ||
| 3/21/2008 | @ | MID | W | 4-3 | 10 | Lilly | L | Tejeda,R | Lee,Cl | L | ||
| 3/22/2008 | CRH | L | 3-8 | Matsuzaka | R | Matsuzaka | Meche | R | ||||
| 3/23/2008 | COP | W | 7-0 | Wakefield | R | Wakefield | Duchscherer | R | ||||
| 3/24/2008 | EDG | W | 13-6 | Weaver | R | Shouse | Danks | L | ||||
| 3/25/2008 | MID | W | 6-2 | Bush | R | Bush | Masterson | Guthrie | R | |||
| 3/26/2008 | @ | CRH | W | 6-3 | Lilly | L | Tejeda,R | Rhodes | Rowland-Smith | L | ||
| 3/27/2008 | @ | COP | W | 7-2 | Matsuzaka | R | Matsuzaka | Harden | R | |||
| 3/30/2008 | ROK | L | 1-2 | Wakefield | R | Wakefield | Santana,J | L | ||||
| 3/31/2008 | GEO | L | 0-5 | Weaver | R | Weaver | Kazmir,Sc | L | ||||
| 4/1/2008 | BON | W | 2-1 | 11 | Bush | R | Shouse | Lowe,D | R | |||
| 4/2/2008 | @ | ROK | W | 9-3 | Lilly | L | Lilly | Johnson,Ra | L | |||
| Other | |||||||||||||
| Cumulative | |||||||||||||
| Date | # | Opp | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# | ||
| 3/1/2008 | @ | GEO | L | 0 | 7 | 0 | 1 | .000 | 0-1 | L1 | 1 | ||
| 3/2/2008 | @ | BON | L | 2 | 3 | 0 | 2 | .000 | 0-2 | L2 | 2 | ||
| 3/4/2008 | @ | Pal | L | 1 | 4 | 0 | 3 | .000 | 0-3 | L3 | 3 | ||
| 3/5/2008 | @ | LON | L | 2 | 11 | 0 | 4 | .000 | 0-4 | L4 | 4 | ||
| 3/6/2008 | CCL | W | Sizemore | 9 | 3 | 1 | 4 | .200 | 1-4 | W1 | 5 | ||
| 3/7/2008 | MAD | W | Rios | 9 | 4 | 2 | 4 | .333 | 2-4 | W2 | 6 | ||
| 3/8/2008 | Pal | W | Roberts,B | 11 | 4 | 3 | 4 | .429 | 3-4 | W3 | 7 | ||
| 3/9/2008 | LON | W | Youkilis | 8 | 5 | 4 | 4 | .500 | 4-4 | W4 | 8 | ||
| 3/10/2008 | @ | CCL | L | 3 | 5 | 4 | 5 | .444 | 4-5 | L1 | 9 | ||
| 3/11/2008 | @ | MAD | W | Youkilis | 7 | 2 | 5 | 5 | .500 | 5-5 | W1 | 10 | |
| 3/12/2008 | @ | TON | W | Zobrist | 6 | 4 | 6 | 5 | .545 | 6-4 | W2 | 11 | |
| 3/13/2008 | @ | WIZ | W | Zobrist | 7 | 6 | 7 | 5 | .583 | 7-3 | W3 | 12 | |
| 3/14/2008 | BT | L | 6 | 7 | 7 | 6 | .538 | 7-3 | L1 | 13 | |||
| 3/15/2008 | MUL | W | Sizemore | 9 | 2 | 8 | 6 | .571 | 8-2 | W1 | 14 | ||
| 3/16/2008 | TON | W | Zobrist | 5 | 4 | 9 | 6 | .600 | 8-2 | W2 | 15 | ||
| 3/17/2008 | WIZ | L | 1 | 11 | 9 | 7 | .563 | 7-3 | L1 | 16 | |||
| 3/18/2008 | @ | BT | W | Youkilis | 6 | 5 | 10 | 7 | .588 | 7-3 | W1 | 17 | |
| 3/19/2008 | @ | MUL | L | 7 | 8 | 10 | 8 | .556 | 6-4 | L1 | 18 | ||
| 3/20/2008 | @ | EDG | W | Rios | 7 | 4 | 11 | 8 | .579 | 7-3 | W1 | 19 | |
| 3/21/2008 | @ | MID | W | Youkilis | 4 | 3 | 12 | 8 | .600 | 7-3 | W2 | 20 | |
| 3/22/2008 | CRH | L | 3 | 8 | 12 | 9 | .571 | 6-4 | L1 | 21 | |||
| 3/23/2008 | COP | W | Youkilis | 7 | 0 | 13 | 9 | .591 | 6-4 | W1 | 22 | ||
| 3/24/2008 | EDG | W | Sizemore | 13 | 6 | 14 | 9 | .609 | 7-3 | W2 | 23 | ||
| 3/25/2008 | MID | W | Jeter | 6 | 2 | 15 | 9 | .625 | 7-3 | W3 | 24 | ||
| 3/26/2008 | @ | CRH | W | Ellsbury | 6 | 3 | 16 | 9 | .640 | 7-3 | W4 | 25 | |
| 3/27/2008 | @ | COP | W | Zobrist | 7 | 2 | 17 | 9 | .654 | 8-2 | W5 | 26 | |
| 3/30/2008 | ROK | L | 1 | 2 | 17 | 10 | .630 | 7-3 | L1 | 27 | |||
| 3/31/2008 | GEO | L | 0 | 5 | 17 | 11 | .607 | 7-3 | L2 | 28 | |||
| 4/1/2008 | BON | W | Sizemore | 2 | 1 | 18 | 11 | .621 | 7-3 | W1 | 29 | ||
| 4/2/2008 | @ | ROK | W | Youkilis | 9 | 3 | 19 | 11 | .633 | 7-3 | W2 | 30 | |