| Primary | |||||||||||||||||
| S | Name | P | AVG | OBP | SPC | AB | H | 2B | 3B | HR | TB | HBP | BB | IW | K | SB | CS |
| Carlson* | mr | .192 | .241 | .287 | 286 | 55 | 15 | 0 | 4 | 82 | 1 | 18 | 3 | 73 | 3 | 0 | |
| Rodriguez,F | cl | .202 | .312 | .305 | 213 | 43 | 14 | 1 | 2 | 65 | 1 | 33 | 1 | 73 | 6 | 0 | |
| Papelbon | cl | .212 | .254 | .338 | 260 | 55 | 5 | 2 | 8 | 88 | 2 | 14 | 0 | 81 | 7 | 1 | |
| Soria | cl | .224 | .319 | .449 | 196 | 44 | 8 | 0 | 12 | 88 | 6 | 22 | 1 | 52 | 2 | 3 | |
| Qualls | mr | .239 | .309 | .325 | 234 | 56 | 6 | 1 | 4 | 76 | 1 | 23 | 1 | 54 | 2 | 4 | |
| Santana,E | sp | .248 | .306 | .443 | 911 | 226 | 43 | 9 | 39 | 404 | 7 | 72 | 5 | 240 | 18 | 8 | |
| f | Neshek | mr | .250 | .250 | .250 | 4 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
| Baker,S | sp | .279 | .328 | .502 | 815 | 227 | 50 | 3 | 42 | 409 | 4 | 62 | 3 | 171 | 11 | 3 | |
| Giese | mr | .283 | .336 | .422 | 427 | 121 | 27 | 4 | 8 | 180 | 4 | 32 | 1 | 75 | 5 | 2 | |
| Lowe,D | sp | .285 | .333 | .432 | 915 | 261 | 49 | 5 | 25 | 395 | 4 | 65 | 0 | 152 | 11 | 7 | |
| Shields,J | sp | .305 | .341 | .531 | 866 | 264 | 67 | 9 | 37 | 460 | 14 | 37 | 0 | 171 | 4 | 3 | |
| Crain | mr | .324 | .398 | .575 | 275 | 89 | 21 | 6 | 12 | 158 | 3 | 33 | 0 | 44 | 3 | 2 | |
| Buehrle* | sp | .366 | .418 | .569 | 418 | 153 | 28 | 3 | 17 | 238 | 3 | 39 | 1 | 68 | 5 | 1 | |
|   | Total |   | .274 | .329 | .454 | 5820 | 1595 | 333 | 43 | 210 | 2644 | 50 | 450 | 16 | 1256 | 77 | 34 |
| Analytical | |||||||||||||
| S | Name | P | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Carlson* | mr | .528 | 212 | .241 | 100 | .325 | 101 | .328 | 20.9 | 2.4 | 2.17 | 1.67 | |
| Rodriguez,F | cl | .617 | 139 | .295 | 98 | .395 | 99 | .399 | 22.0 | 3.4 | 3.04 | 2.84 | |
| Papelbon | cl | .593 | 175 | .269 | 102 | .364 | 104 | .371 | 23.1 | 2.9 | 2.63 | 2.33 | |
| Soria | cl | .768 | 134 | .239 | 110 | .487 | 116 | .513 | 28.4 | 4.8 | 4.33 | 4.50 | |
| Qualls | mr | .634 | 178 | .292 | 99 | .381 | 100 | .385 | 21.3 | 3.0 | 2.69 | 3.11 | |
| Santana,E | sp | .750 | 640 | .292 | 476 | .477 | 483 | .484 | 126.5 | 4.8 | 4.35 | 3.98 | |
| f | Neshek | mr | .500 | 3 | .333 | 1 | .200 | 1 | .200 | 0.3 | 2.1 | 1.85 | 1.13 |
| Baker,S | sp | .830 | 618 | .299 | 471 | .525 | 475 | .530 | 137.2 | 6.0 | 5.41 | 5.04 | |
| Giese | mr | .758 | 349 | .324 | 212 | .453 | 216 | .462 | 63.1 | 5.4 | 4.84 | 4.42 | |
| Lowe,D | sp | .765 | 748 | .316 | 460 | .463 | 464 | .467 | 124.9 | 4.8 | 4.32 | 4.44 | |
| Shields,J | sp | .872 | 666 | .341 | 497 | .537 | 511 | .552 | 150.8 | 6.4 | 5.83 | 5.49 | |
| Crain | mr | .973 | 225 | .342 | 191 | .603 | 194 | .612 | 65.1 | 8.9 | 8.12 | 7.57 | |
| Buehrle* | sp | .988 | 340 | .400 | 277 | .593 | 280 | .600 | 99.9 | 9.5 | 8.46 | 8.69 | |
|   | Total |   | .783 | 4427 | .313 | 3094 | .484 | 3144 | .492 | 868.6 | 5.3 | 4.76 | 4.56 |
| vs LHB | ||||||||||||||||||
|   |   |   | Versus Left-handed Batters | |||||||||||||||
| S | Name | P | AVG | OBP | SPC | OPS | AB | H | 2B | 3B | HR | RBI | HBP | BB | IBB | K | SH | SF |
| Carlson* | mr | .165 | .208 | .198 | .406 | 91 | 15 | 3 | 0 | 0 | 5 | 1 | 4 | 0 | 21 | 0 | 0 | |
| Rodriguez,F | cl | .138 | .291 | .216 | .506 | 116 | 16 | 6 | 0 | 1 | 9 | 0 | 25 | 1 | 49 | 0 | 0 | |
| Papelbon | cl | .175 | .224 | .294 | .518 | 143 | 25 | 4 | 2 | 3 | 14 | 0 | 10 | 0 | 49 | 1 | 3 | |
| Soria | cl | .209 | .328 | .382 | .710 | 110 | 23 | 4 | 0 | 5 | 20 | 2 | 18 | 0 | 27 | 0 | 1 | |
| Qualls | mr | .218 | .297 | .306 | .604 | 124 | 27 | 3 | 1 | 2 | 16 | 0 | 14 | 1 | 29 | 0 | 0 | |
| Santana,E | sp | .238 | .313 | .438 | .751 | 504 | 120 | 25 | 5 | 22 | 54 | 5 | 51 | 5 | 141 | 1 | 3 | |
| f | Neshek | mr | .000 | .000 | .000 | .000 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Baker,S | sp | .310 | .364 | .539 | .903 | 449 | 139 | 36 | 2 | 21 | 65 | 1 | 43 | 3 | 102 | 4 | 10 | |
| Giese | mr | .241 | .311 | .415 | .726 | 241 | 58 | 19 | 4 | 5 | 45 | 0 | 26 | 0 | 45 | 0 | 3 | |
| Lowe,D | sp | .274 | .327 | .369 | .696 | 518 | 142 | 31 | 3 | 4 | 38 | 3 | 39 | 0 | 76 | 1 | 2 | |
| Shields,J | sp | .308 | .346 | .565 | .911 | 497 | 153 | 43 | 8 | 23 | 88 | 4 | 27 | 0 | 103 | 2 | 4 | |
| Crain | mr | .306 | .405 | .456 | .860 | 147 | 45 | 9 | 2 | 3 | 23 | 1 | 24 | 0 | 30 | 1 | 1 | |
| Buehrle* | sp | .471 | .530 | .735 | 1.265 | 102 | 48 | 10 | 1 | 5 | 25 | 1 | 13 | 0 | 13 | 0 | 1 | |
|   | Total |   | .266 | .332 | .441 | .773 | 3044 | 811 | 193 | 28 | 94 | 402 | 18 | 294 | 10 | 686 | 10 | 28 |
| vs RHB | ||||||||||||||||||
|   |   |   | Versus Right-handed Batters | |||||||||||||||
| S | Name | P | AVG | OBP | SPC | OPS | AB | H | 2B | 3B | HR | RBI | HBP | BB | IBB | K | SH | SF |
| Carlson* | mr | .205 | .256 | .328 | .584 | 195 | 40 | 12 | 0 | 4 | 17 | 0 | 14 | 3 | 52 | 1 | 2 | |
| Rodriguez,F | cl | .278 | .340 | .412 | .752 | 97 | 27 | 8 | 1 | 1 | 18 | 1 | 8 | 0 | 24 | 0 | 0 | |
| Papelbon | cl | .256 | .293 | .393 | .686 | 117 | 30 | 1 | 0 | 5 | 16 | 2 | 4 | 0 | 32 | 0 | 0 | |
| Soria | cl | .244 | .305 | .535 | .840 | 86 | 21 | 4 | 0 | 7 | 17 | 4 | 4 | 1 | 25 | 0 | 1 | |
| Qualls | mr | .264 | .322 | .345 | .668 | 110 | 29 | 3 | 0 | 2 | 8 | 1 | 9 | 0 | 25 | 1 | 1 | |
| Santana,E | sp | .260 | .298 | .450 | .748 | 407 | 106 | 18 | 4 | 17 | 55 | 2 | 21 | 0 | 99 | 1 | 3 | |
| f | Neshek | mr | .500 | .500 | .500 | 1.000 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| Baker,S | sp | .240 | .283 | .456 | .739 | 366 | 88 | 14 | 1 | 21 | 49 | 3 | 19 | 0 | 69 | 1 | 1 | |
| Giese | mr | .339 | .371 | .430 | .801 | 186 | 63 | 8 | 0 | 3 | 17 | 4 | 6 | 1 | 30 | 1 | 1 | |
| Lowe,D | sp | .300 | .340 | .514 | .854 | 397 | 119 | 18 | 2 | 21 | 70 | 1 | 26 | 0 | 76 | 2 | 5 | |
| Shields,J | sp | .301 | .335 | .485 | .820 | 369 | 111 | 24 | 1 | 14 | 53 | 10 | 10 | 0 | 68 | 0 | 2 | |
| Crain | mr | .344 | .390 | .711 | 1.101 | 128 | 44 | 12 | 4 | 9 | 34 | 2 | 9 | 0 | 14 | 2 | 2 | |
| Buehrle* | sp | .332 | .381 | .516 | .897 | 316 | 105 | 18 | 2 | 12 | 65 | 2 | 26 | 1 | 55 | 1 | 5 | |
|   | Total |   | .282 | .325 | .469 | .794 | 2776 | 784 | 140 | 15 | 116 | 419 | 32 | 156 | 6 | 570 | 11 | 23 |