Real-life pitching register -- All players in database
Regular season
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | EDG | mr | 26 | 5.55 | 4 | 2 | 0 | 47 | 0 | 0 | 0 | 48.2 | 49 | 32 | 30 | 35 | 49 | 4 | 4 |
| Jeremy Accardo |   | mr | 26 | 6.57 | 0 | 3 | 4 | 16 | 0 | 0 | 0 | 12.1 | 15 | 10 | 9 | 4 | 5 | 1 | 3 |
| Alfredo Aceves |   | sp | 25 | 2.40 | 1 | 0 | 0 | 6 | 4 | 0 | 0 | 30.0 | 25 | 8 | 8 | 10 | 16 | 4 | 3 |
| Manny Acosta |   | mr | 27 | 3.57 | 3 | 5 | 3 | 46 | 0 | 0 | 0 | 53.0 | 48 | 25 | 21 | 26 | 31 | 7 | 7 |
| Mike Adams | MUL | mr | 29 | 2.48 | 2 | 3 | 0 | 54 | 0 | 0 | 0 | 65.1 | 49 | 18 | 18 | 19 | 74 | 7 | 2 |
| Nick Adenhart |   | sp | 21 | 9.00 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 12.0 | 18 | 12 | 12 | 13 | 4 | 0 | 3 |
| Jon Adkins |   | mr | 30 | 2.45 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 3.2 | 4 | 1 | 1 | 3 | 3 | 1 | 1 |
| Jeremy Affeldt* | CRH | mr | 29 | 3.33 | 1 | 1 | 0 | 74 | 0 | 0 | 0 | 78.1 | 78 | 36 | 29 | 25 | 80 | 9 | 7 |
| Jonathan Albaladejo |   | mr | 25 | 3.95 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 13.2 | 15 | 6 | 6 | 6 | 13 | 1 | 2 |
| Matt Albers |   | mr | 25 | 3.49 | 3 | 3 | 0 | 28 | 3 | 0 | 0 | 49.0 | 43 | 21 | 19 | 22 | 26 | 4 | 9 |
| Greg Aquino |   | mr | 30 | 12.54 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 9.1 | 17 | 13 | 13 | 9 | 9 | 1 | 0 |
| Alberto Arias |   | mr | 24 | 4.15 | 1 | 1 | 0 | 15 | 2 | 0 | 0 | 21.2 | 23 | 10 | 10 | 10 | 13 | 1 | 4 |
| Tony Armas |   | mr | 30 | 7.56 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 8.1 | 11 | 7 | 7 | 1 | 6 | 2 | 0 |
| Jose Arredondo | COP | mr | 24 | 1.62 | 10 | 2 | 0 | 52 | 0 | 0 | 0 | 61.0 | 42 | 15 | 11 | 22 | 55 | 3 | 6 |
| Bronson Arroyo | BT | sp | 31 | 4.77 | 15 | 11 | 0 | 34 | 34 | 1 | 0 | 200.0 | 219 | 116 | 106 | 68 | 163 | 29 | 20 |
| Jose Ascanio |   | mr | 23 | 7.94 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 5.2 | 8 | 5 | 5 | 4 | 3 | 1 | 0 |
| Luis Ayala |   | mr | 30 | 5.71 | 2 | 10 | 9 | 81 | 0 | 0 | 0 | 75.2 | 86 | 53 | 48 | 24 | 50 | 9 | 7 |
| Brandon Backe |   | sp | 30 | 6.05 | 9 | 14 | 0 | 31 | 31 | 0 | 0 | 166.2 | 202 | 114 | 112 | 77 | 127 | 36 | 17 |
| Burke Badenhop |   | sp | 25 | 6.08 | 2 | 3 | 0 | 13 | 8 | 0 | 0 | 47.1 | 55 | 34 | 32 | 21 | 35 | 7 | 2 |
| Cha Seung Baek |   | sp | 28 | 4.79 | 6 | 10 | 0 | 32 | 21 | 0 | 0 | 141.0 | 146 | 78 | 75 | 43 | 92 | 18 | 11 |
| Homer Bailey |   | sp | 22 | 7.93 | 0 | 6 | 0 | 8 | 8 | 0 | 0 | 36.1 | 59 | 36 | 32 | 17 | 18 | 8 | 3 |
| Scott Baker | BON | sp | 26 | 3.45 | 11 | 4 | 0 | 28 | 28 | 0 | 0 | 172.1 | 161 | 66 | 66 | 42 | 141 | 20 | 12 |
| John Bale* |   | mr | 34 | 4.39 | 0 | 3 | 0 | 13 | 3 | 0 | 0 | 26.2 | 29 | 13 | 13 | 6 | 14 | 1 | 5 |
| Collin Balester |   | sp | 22 | 5.51 | 3 | 7 | 0 | 15 | 15 | 0 | 0 | 80.0 | 92 | 53 | 49 | 28 | 50 | 12 | 7 |
| Grant Balfour | COP | mr | 30 | 1.54 | 6 | 2 | 4 | 51 | 0 | 0 | 0 | 58.1 | 28 | 10 | 10 | 24 | 82 | 3 | 0 |
| Josh Banks |   | sp | 25 | 4.75 | 3 | 6 | 0 | 17 | 14 | 1 | 0 | 85.1 | 94 | 47 | 45 | 32 | 43 | 12 | 7 |
| Brian Bannister |   | sp | 27 | 5.76 | 9 | 16 | 0 | 32 | 32 | 1 | 0 | 182.2 | 215 | 127 | 117 | 58 | 113 | 29 | 15 |
| Jimmy Barthmaier |   | sp | 24 | 10.45 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 10.1 | 16 | 12 | 12 | 8 | 6 | 3 | 1 |
| Brian Bass |   | mr | 26 | 4.84 | 4 | 4 | 1 | 49 | 4 | 0 | 0 | 89.1 | 98 | 55 | 48 | 31 | 45 | 12 | 15 |
| Miguel Batista |   | mr | 37 | 6.26 | 4 | 14 | 1 | 44 | 20 | 0 | 0 | 115.0 | 135 | 89 | 80 | 79 | 73 | 19 | 7 |
| Rick Bauer |   | mr | 31 | 13.50 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.0 | 10 | 9 | 9 | 3 | 4 | 1 | 1 |
| Denny Bautista |   | mr | 27 | 5.22 | 4 | 4 | 0 | 51 | 0 | 0 | 0 | 60.1 | 61 | 35 | 35 | 42 | 44 | 6 | 11 |
| Yorman Bazardo |   | mr | 23 | 24.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.0 | 7 | 8 | 8 | 5 | 3 | 0 | 0 |
| T.J. Beam |   | mr | 27 | 4.14 | 2 | 2 | 1 | 32 | 0 | 0 | 0 | 45.2 | 43 | 21 | 21 | 20 | 24 | 6 | 2 |
| Josh Beckett | Pal | sp | 28 | 4.03 | 12 | 10 | 0 | 27 | 27 | 1 | 0 | 174.1 | 173 | 80 | 78 | 34 | 172 | 18 | 9 |
| Erik Bedard* | GEO | sp | 29 | 3.67 | 6 | 4 | 0 | 15 | 15 | 0 | 0 | 81.0 | 70 | 38 | 33 | 37 | 72 | 9 | 10 |
| Joe Beimel* |   | mr | 31 | 2.02 | 5 | 1 | 0 | 71 | 0 | 0 | 0 | 49.0 | 50 | 11 | 11 | 21 | 32 | 0 | 4 |
| Matt Belisle |   | sp | 28 | 7.28 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 29.2 | 47 | 27 | 24 | 6 | 14 | 4 | 3 |
| Heath Bell | MUL | mr | 30 | 3.58 | 6 | 6 | 0 | 74 | 0 | 0 | 0 | 78.0 | 66 | 31 | 31 | 28 | 71 | 5 | 5 |
| Francis Beltran |   | mr | 28 | 4.85 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 13.0 | 13 | 7 | 7 | 6 | 9 | 3 | 2 |
| Armando Benitez |   | mr | 35 | 5.68 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 6.1 | 4 | 5 | 4 | 2 | 9 | 3 | 0 |
| Jeff Bennett | TON | mr | 28 | 3.70 | 3 | 7 | 3 | 72 | 4 | 0 | 0 | 97.1 | 86 | 44 | 40 | 47 | 68 | 5 | 13 |
| Joaquin Benoit | OTR | mr | 30 | 5.00 | 3 | 2 | 1 | 44 | 0 | 0 | 0 | 45.0 | 40 | 28 | 25 | 35 | 43 | 6 | 2 |
| Jason Bergmann |   | sp | 26 | 5.09 | 2 | 11 | 0 | 30 | 22 | 1 | 0 | 139.2 | 153 | 94 | 79 | 47 | 96 | 25 | 9 |
| Rafael Betancourt | GEO | mr | 33 | 5.07 | 3 | 4 | 4 | 69 | 0 | 0 | 0 | 71.0 | 76 | 41 | 40 | 25 | 64 | 11 | 3 |
| Randor Bierd |   | mr | 24 | 4.91 | 0 | 2 | 0 | 29 | 0 | 0 | 0 | 36.2 | 48 | 21 | 20 | 19 | 25 | 3 | 2 |
| Chad Billingsley | TON | sp | 23 | 3.14 | 16 | 10 | 0 | 35 | 32 | 1 | 1 | 200.2 | 188 | 76 | 70 | 80 | 201 | 14 | 18 |
| Kurt Birkins* |   | mr | 27 | 0.90 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 10.0 | 5 | 1 | 1 | 5 | 7 | 0 | 3 |
| Nick Blackburn |   | sp | 26 | 4.05 | 11 | 11 | 0 | 33 | 33 | 0 | 0 | 193.1 | 224 | 102 | 87 | 39 | 96 | 23 | 31 |
| Joe Blanton |   | sp | 27 | 4.69 | 9 | 12 | 0 | 33 | 33 | 0 | 0 | 197.2 | 211 | 110 | 103 | 66 | 111 | 22 | 19 |
| Jerry Blevins* |   | mr | 24 | 3.11 | 1 | 3 | 0 | 36 | 0 | 0 | 0 | 37.2 | 32 | 14 | 13 | 13 | 35 | 2 | 3 |
| Mitchell Boggs |   | sp | 24 | 7.41 | 3 | 2 | 0 | 8 | 6 | 0 | 0 | 34.0 | 42 | 29 | 28 | 22 | 13 | 5 | 4 |
| Jeremy Bonderman |   | sp | 25 | 4.29 | 3 | 4 | 0 | 12 | 12 | 0 | 0 | 71.1 | 75 | 39 | 34 | 36 | 44 | 9 | 8 |
| Eddie Bonine |   | sp | 27 | 5.40 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 26.2 | 36 | 19 | 16 | 5 | 9 | 3 | 8 |
| Boof Bonser |   | mr | 26 | 5.93 | 3 | 7 | 0 | 47 | 12 | 0 | 0 | 118.1 | 139 | 87 | 78 | 36 | 97 | 16 | 7 |
| Chris Bootcheck |   | mr | 29 | 10.13 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 16.0 | 30 | 18 | 18 | 12 | 14 | 2 | 0 |
| Dave Borkowski |   | mr | 31 | 7.50 | 0 | 2 | 0 | 26 | 0 | 0 | 0 | 36.0 | 54 | 30 | 30 | 14 | 24 | 9 | 3 |
| Joe Borowski |   | cl | 37 | 7.56 | 1 | 3 | 6 | 18 | 0 | 0 | 0 | 16.2 | 24 | 14 | 14 | 8 | 9 | 4 | 0 |
| Michael Bowden |   | sp | 21 | 3.60 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 7 | 2 | 2 | 1 | 3 | 0 | 0 |
| Cedrick Bowers* |   | mr | 30 | 13.50 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.2 | 11 | 10 | 10 | 5 | 5 | 2 | 2 |
| Micah Bowie* |   | mr | 33 | 9.00 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 8.0 | 11 | 8 | 8 | 3 | 5 | 1 | 2 |
| Blaine Boyer |   | mr | 26 | 5.88 | 2 | 6 | 1 | 76 | 0 | 0 | 0 | 72.0 | 73 | 51 | 47 | 25 | 67 | 10 | 2 |
| Dallas Braden* |   | sp | 24 | 4.14 | 5 | 4 | 0 | 19 | 10 | 0 | 0 | 71.2 | 77 | 36 | 33 | 25 | 41 | 8 | 7 |
| Chad Bradford | MID | mr | 33 | 2.12 | 4 | 3 | 0 | 68 | 0 | 0 | 0 | 59.1 | 59 | 20 | 14 | 15 | 17 | 3 | 12 |
| Bill Bray* |   | mr | 25 | 2.87 | 2 | 2 | 0 | 63 | 0 | 0 | 0 | 47.0 | 50 | 19 | 15 | 24 | 54 | 4 | 3 |
| Yhency Brazoban |   | mr | 28 | 6.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 4 | 2 | 2 | 3 | 3 | 0 | 1 |
| Craig Breslow* | MID | mr | 27 | 1.91 | 0 | 2 | 1 | 49 | 0 | 0 | 0 | 47.0 | 34 | 12 | 10 | 19 | 39 | 1 | 1 |
| Chris Britton |   | mr | 25 | 5.09 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 23.0 | 28 | 13 | 13 | 11 | 12 | 4 | 1 |
| Lance Broadway |   | mr | 24 | 7.07 | 1 | 0 | 0 | 7 | 1 | 0 | 0 | 14.0 | 20 | 11 | 11 | 5 | 7 | 4 | 1 |
| Doug Brocail |   | mr | 41 | 3.93 | 7 | 5 | 2 | 72 | 0 | 0 | 0 | 68.2 | 63 | 30 | 30 | 21 | 64 | 8 | 5 |
| Andrew Brown |   | mr | 27 | 3.09 | 1 | 0 | 0 | 31 | 0 | 0 | 0 | 35.0 | 23 | 13 | 12 | 21 | 28 | 3 | 4 |
| Jonathan Broxton | CCL | mr | 24 | 3.13 | 3 | 5 | 14 | 70 | 0 | 0 | 0 | 69.0 | 54 | 29 | 24 | 27 | 88 | 2 | 6 |
| Brian Bruney |   | mr | 26 | 1.83 | 3 | 0 | 1 | 32 | 1 | 0 | 0 | 34.1 | 18 | 7 | 7 | 16 | 33 | 2 | 0 |
| Clay Buchholz | COP | sp | 23 | 6.75 | 2 | 9 | 0 | 16 | 15 | 1 | 0 | 76.0 | 93 | 63 | 57 | 41 | 72 | 11 | 4 |
| Taylor Buchholz | TON | mr | 26 | 2.17 | 6 | 6 | 1 | 63 | 0 | 0 | 0 | 66.1 | 45 | 23 | 16 | 18 | 56 | 5 | 4 |
| Billy Buckner |   | mr | 24 | 3.21 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 14.0 | 16 | 5 | 5 | 4 | 11 | 3 | 4 |
| Mark Buehrle* | BON | sp | 29 | 3.79 | 15 | 12 | 0 | 34 | 34 | 1 | 0 | 218.2 | 240 | 106 | 92 | 52 | 140 | 22 | 34 |
| Francisley Bueno* |   | mr | 27 | 7.71 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.1 | 5 | 2 | 2 | 1 | 1 | 1 | 0 |
| Ryan Bukvich |   | mr | 30 | 6.75 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.1 | 9 | 4 | 4 | 6 | 5 | 2 | 1 |
| Jason Bulger |   | mr | 29 | 7.31 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 16.0 | 15 | 13 | 13 | 9 | 20 | 3 | 1 |
| Bryan Bullington |   | sp | 27 | 4.91 | 0 | 2 | 0 | 3 | 2 | 0 | 0 | 14.2 | 15 | 9 | 8 | 2 | 12 | 4 | 2 |
| A.J. Burnett | TON | sp | 31 | 4.07 | 18 | 10 | 0 | 35 | 34 | 1 | 0 | 221.1 | 211 | 109 | 100 | 86 | 231 | 19 | 12 |
| Sean Burnett* | WIZ | mr | 25 | 4.76 | 1 | 1 | 0 | 58 | 0 | 0 | 0 | 56.2 | 57 | 31 | 30 | 34 | 42 | 7 | 8 |
| Brian Burres* |   | sp | 27 | 6.04 | 7 | 10 | 0 | 31 | 22 | 0 | 0 | 129.2 | 165 | 90 | 87 | 50 | 63 | 17 | 8 |
| Jared Burton | MAD | mr | 27 | 3.22 | 5 | 1 | 0 | 54 | 0 | 0 | 0 | 58.2 | 56 | 24 | 21 | 25 | 58 | 6 | 3 |
| Dave Bush | OTR | sp | 28 | 4.18 | 9 | 10 | 0 | 31 | 29 | 0 | 0 | 185.0 | 163 | 92 | 86 | 48 | 109 | 29 | 13 |
| Paul Byrd |   | sp | 37 | 4.60 | 11 | 12 | 0 | 30 | 30 | 1 | 0 | 180.0 | 204 | 96 | 92 | 34 | 82 | 31 | 14 |
| Tim Byrdak* |   | mr | 34 | 3.90 | 2 | 1 | 0 | 59 | 0 | 0 | 0 | 55.1 | 45 | 24 | 24 | 29 | 47 | 10 | 3 |
| Daniel Cabrera |   | sp | 27 | 5.25 | 8 | 10 | 0 | 30 | 30 | 2 | 0 | 180.0 | 199 | 109 | 105 | 90 | 95 | 24 | 22 |
| Fernando Cabrera |   | mr | 26 | 5.40 | 2 | 1 | 0 | 22 | 0 | 0 | 0 | 28.1 | 32 | 18 | 17 | 17 | 31 | 9 | 1 |
| Matt Cain | LON | sp | 23 | 3.76 | 8 | 14 | 0 | 34 | 34 | 1 | 1 | 217.2 | 206 | 95 | 91 | 91 | 186 | 19 | 10 |
| Kiko Calero |   | mr | 33 | 3.86 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.2 | 3 | 3 | 2 | 3 | 7 | 0 | 0 |
| Kevin Cameron |   | mr | 28 | 3.60 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 10.0 | 10 | 9 | 4 | 6 | 5 | 0 | 0 |
| Shawn Camp |   | mr | 32 | 4.12 | 3 | 1 | 0 | 40 | 0 | 0 | 0 | 39.1 | 40 | 18 | 18 | 11 | 31 | 2 | 5 |
| Jorge Campillo | WIZ | sp | 29 | 3.91 | 8 | 7 | 0 | 39 | 25 | 1 | 0 | 158.2 | 158 | 74 | 69 | 38 | 107 | 18 | 12 |
| Jose Capellan |   | mr | 27 | 4.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 3 | 1 | 1 | 0 | 2 | 0 | 0 |
| Matt Capps | MUL | cl | 24 | 3.02 | 2 | 3 | 21 | 49 | 0 | 0 | 0 | 53.2 | 47 | 20 | 18 | 5 | 39 | 5 | 3 |
| Jesse Carlson* | BON | mr | 27 | 2.25 | 7 | 2 | 2 | 69 | 0 | 0 | 0 | 60.0 | 41 | 16 | 15 | 21 | 55 | 6 | 3 |
| Buddy Carlyle | LON | mr | 30 | 3.59 | 2 | 0 | 0 | 45 | 0 | 0 | 0 | 62.2 | 52 | 26 | 25 | 26 | 59 | 5 | 5 |
| Fausto Carmona |   | sp | 24 | 5.44 | 8 | 7 | 0 | 22 | 22 | 1 | 1 | 120.2 | 126 | 80 | 73 | 70 | 58 | 7 | 26 |
| Andrew Carpenter |   | mr | 23 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
| Chris Carpenter | TON | sp | 33 | 1.76 | 0 | 1 | 0 | 4 | 3 | 0 | 0 | 15.1 | 16 | 5 | 3 | 4 | 7 | 0 | 3 |
| D.J. Carrasco |   | mr | 31 | 3.96 | 1 | 0 | 0 | 31 | 0 | 0 | 0 | 38.2 | 30 | 17 | 17 | 14 | 30 | 2 | 4 |
| Santiago Casilla | OTR | mr | 27 | 3.93 | 2 | 1 | 2 | 51 | 0 | 0 | 0 | 50.1 | 60 | 22 | 22 | 20 | 43 | 5 | 6 |
| Jack Cassel |   | mr | 27 | 5.64 | 1 | 1 | 0 | 9 | 3 | 0 | 0 | 30.1 | 38 | 21 | 19 | 8 | 14 | 5 | 5 |
| Alberto Castillo* |   | mr | 32 | 3.81 | 1 | 0 | 0 | 28 | 0 | 0 | 0 | 26.0 | 27 | 11 | 11 | 10 | 23 | 3 | 1 |
| Shawn Chacon |   | sp | 30 | 5.04 | 2 | 3 | 0 | 15 | 15 | 0 | 0 | 85.2 | 88 | 52 | 48 | 41 | 53 | 16 | 9 |
| Joba Chamberlain | BT | mr | 22 | 2.60 | 4 | 3 | 0 | 42 | 12 | 0 | 0 | 100.1 | 87 | 32 | 29 | 39 | 118 | 5 | 5 |
| Jesse Chavez |   | mr | 24 | 6.60 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 15.0 | 20 | 11 | 11 | 9 | 16 | 2 | 0 |
| Rocky Cherry |   | mr | 28 | 6.35 | 0 | 3 | 1 | 18 | 0 | 0 | 0 | 17.0 | 15 | 15 | 12 | 16 | 15 | 3 | 1 |
| Matt Chico* |   | sp | 25 | 6.19 | 0 | 6 | 0 | 11 | 8 | 0 | 0 | 48.0 | 63 | 34 | 33 | 17 | 31 | 10 | 4 |
| Vinnie Chulk |   | mr | 29 | 4.83 | 0 | 3 | 0 | 27 | 0 | 0 | 0 | 31.2 | 33 | 18 | 17 | 8 | 16 | 6 | 1 |
| Tyler Clippard |   | sp | 23 | 4.35 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 10.1 | 12 | 5 | 5 | 7 | 8 | 2 | 1 |
| Todd Coffey |   | mr | 27 | 4.39 | 1 | 0 | 0 | 26 | 0 | 0 | 0 | 26.2 | 31 | 13 | 13 | 8 | 15 | 4 | 5 |
| Phil Coke* |   | mr | 25 | 0.61 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 14.2 | 8 | 1 | 1 | 2 | 14 | 0 | 2 |
| Jesus Colome |   | mr | 30 | 4.31 | 2 | 2 | 0 | 61 | 0 | 0 | 0 | 71.0 | 61 | 38 | 34 | 39 | 55 | 6 | 6 |
| Bartolo Colon |   | sp | 35 | 3.92 | 4 | 2 | 0 | 7 | 7 | 0 | 0 | 39.0 | 44 | 23 | 17 | 10 | 27 | 5 | 3 |
| Clay Condrey |   | mr | 32 | 3.26 | 3 | 4 | 1 | 56 | 0 | 0 | 0 | 69.0 | 85 | 26 | 25 | 19 | 34 | 6 | 10 |
| Jose Contreras |   | sp | 36 | 4.54 | 7 | 6 | 0 | 20 | 20 | 1 | 0 | 121.0 | 130 | 64 | 61 | 35 | 70 | 12 | 10 |
| Aaron Cook | MAD | sp | 29 | 3.96 | 16 | 9 | 0 | 32 | 32 | 2 | 1 | 211.1 | 236 | 102 | 93 | 48 | 96 | 13 | 29 |
| Roy Corcoran | EDG | mr | 28 | 3.22 | 6 | 2 | 3 | 50 | 0 | 0 | 0 | 72.2 | 65 | 31 | 26 | 36 | 39 | 1 | 11 |
| Chad Cordero |   | mr | 26 | 2.08 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 4.1 | 6 | 1 | 1 | 3 | 5 | 0 | 0 |
| Francisco Cordero | CRH | cl | 33 | 3.33 | 5 | 4 | 34 | 72 | 0 | 0 | 0 | 70.1 | 61 | 28 | 26 | 38 | 78 | 6 | 5 |
| Bryan Corey |   | mr | 34 | 6.80 | 1 | 3 | 0 | 46 | 0 | 0 | 0 | 45.0 | 53 | 34 | 34 | 12 | 22 | 8 | 1 |
| Lance Cormier |   | mr | 27 | 4.02 | 3 | 3 | 1 | 45 | 1 | 0 | 0 | 71.2 | 78 | 36 | 32 | 34 | 46 | 4 | 7 |
| Manuel Corpas |   | mr | 25 | 4.52 | 3 | 4 | 4 | 76 | 0 | 0 | 0 | 79.2 | 93 | 41 | 40 | 23 | 50 | 7 | 10 |
| Kevin Correia | MUL | sp | 27 | 6.05 | 3 | 8 | 0 | 25 | 19 | 0 | 0 | 110.0 | 141 | 80 | 74 | 47 | 66 | 15 | 8 |
| Neal Cotts* | CRH | mr | 28 | 4.29 | 0 | 2 | 0 | 50 | 0 | 0 | 0 | 35.2 | 38 | 18 | 17 | 13 | 43 | 7 | 2 |
| Jesse Crain | BON | mr | 26 | 3.59 | 5 | 4 | 0 | 66 | 0 | 0 | 0 | 62.2 | 62 | 29 | 25 | 24 | 50 | 6 | 4 |
| Francisco Cruceta |   | mr | 26 | 5.40 | 0 | 3 | 0 | 13 | 0 | 0 | 0 | 11.2 | 13 | 8 | 7 | 10 | 11 | 2 | 2 |
| Juan Cruz | TON | mr | 29 | 2.61 | 4 | 0 | 0 | 57 | 0 | 0 | 0 | 51.2 | 34 | 17 | 15 | 31 | 71 | 5 | 2 |
| Johnny Cueto | Pal | sp | 22 | 4.81 | 9 | 14 | 0 | 31 | 31 | 0 | 0 | 174.0 | 178 | 101 | 93 | 68 | 158 | 29 | 11 |
| John Danks* | EDG | sp | 23 | 3.32 | 12 | 9 | 0 | 33 | 33 | 0 | 0 | 195.0 | 182 | 74 | 72 | 57 | 159 | 15 | 15 |
| Kyle Davies |   | sp | 24 | 4.06 | 9 | 7 | 0 | 21 | 21 | 0 | 0 | 113.0 | 121 | 57 | 51 | 43 | 71 | 10 | 14 |
| Doug Davis* |   | sp | 32 | 4.32 | 6 | 8 | 0 | 26 | 26 | 0 | 0 | 146.0 | 160 | 76 | 70 | 64 | 112 | 13 | 15 |
| Jason Davis |   | mr | 28 | 5.29 | 2 | 4 | 0 | 14 | 4 | 0 | 0 | 34.0 | 38 | 24 | 20 | 17 | 13 | 2 | 8 |
| Eulogio De La Cruz |   | mr | 24 | 18.00 | 0 | 0 | 0 | 6 | 1 | 0 | 0 | 9.0 | 15 | 20 | 18 | 11 | 4 | 2 | 1 |
| Jorge De La Rosa* | MUL | sp | 27 | 4.92 | 10 | 8 | 0 | 28 | 23 | 0 | 0 | 130.0 | 128 | 77 | 71 | 62 | 128 | 13 | 11 |
| Valerio de los Santos* |   | sp | 35 | 5.63 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 8.0 | 6 | 5 | 5 | 11 | 10 | 1 | 1 |
| Manny Delcarmen | GEO | mr | 26 | 3.27 | 1 | 2 | 2 | 73 | 0 | 0 | 0 | 74.1 | 55 | 28 | 27 | 28 | 72 | 5 | 4 |
| Jesus Delgado |   | mr | 24 | 4.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 1 | 1 | 1 | 3 | 0 | 0 | 0 |
| Ryan Dempster | CRH | sp | 31 | 2.96 | 17 | 6 | 0 | 33 | 33 | 1 | 0 | 206.2 | 174 | 75 | 68 | 76 | 187 | 14 | 19 |
| Matt DeSalvo |   | mr | 27 | 31.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 11 | 7 | 7 | 2 | 2 | 0 | 1 |
| Elmer Dessens |   | mr | 37 | 22.50 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 4.0 | 10 | 10 | 10 | 4 | 2 | 1 | 0 |
| Joey Devine | BT | mr | 24 | 0.59 | 6 | 1 | 1 | 42 | 0 | 0 | 0 | 45.2 | 23 | 7 | 3 | 15 | 49 | 0 | 3 |
| Joselo Diaz |   | mr | 28 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 1 | 0 | 1 | 2 | 0 | 0 |
| R.A. Dickey | OTR | mr | 33 | 5.21 | 5 | 8 | 0 | 32 | 14 | 0 | 0 | 112.1 | 124 | 65 | 65 | 51 | 58 | 15 | 6 |
| Mark DiFelice |   | mr | 31 | 2.84 | 1 | 0 | 0 | 15 | 0 | 0 | 0 | 19.0 | 17 | 7 | 6 | 4 | 20 | 4 | 1 |
| Tim Dillard |   | mr | 24 | 4.40 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 14.1 | 17 | 12 | 7 | 6 | 5 | 2 | 2 |
| Lenny DiNardo* |   | mr | 28 | 7.43 | 1 | 2 | 0 | 11 | 2 | 0 | 0 | 23.0 | 31 | 20 | 19 | 13 | 12 | 3 | 4 |
| Scott Dohmann |   | mr | 30 | 6.14 | 2 | 0 | 0 | 12 | 0 | 0 | 0 | 14.2 | 18 | 10 | 10 | 7 | 12 | 2 | 2 |
| Freddy Dolsi |   | mr | 25 | 3.97 | 1 | 5 | 2 | 42 | 0 | 0 | 0 | 47.2 | 50 | 21 | 21 | 28 | 29 | 3 | 4 |
| Brendan Donnelly |   | mr | 36 | 8.56 | 1 | 0 | 0 | 15 | 0 | 0 | 0 | 13.2 | 20 | 13 | 13 | 10 | 8 | 2 | 0 |
| Octavio Dotel |   | mr | 34 | 3.76 | 4 | 4 | 1 | 72 | 0 | 0 | 0 | 67.0 | 52 | 34 | 28 | 29 | 92 | 12 | 2 |
| Scott Downs* | EDG | mr | 32 | 1.78 | 0 | 3 | 5 | 66 | 0 | 0 | 0 | 70.2 | 54 | 15 | 14 | 27 | 57 | 3 | 8 |
| Justin Duchscherer | COP | sp | 30 | 2.54 | 10 | 8 | 0 | 22 | 22 | 1 | 1 | 141.2 | 107 | 45 | 40 | 34 | 95 | 11 | 13 |
| Brandon Duckworth |   | sp | 32 | 4.50 | 3 | 3 | 0 | 7 | 7 | 0 | 0 | 38.0 | 38 | 20 | 19 | 19 | 20 | 2 | 4 |
| Zach Duke* |   | sp | 25 | 4.82 | 5 | 14 | 0 | 31 | 31 | 1 | 1 | 185.0 | 230 | 111 | 99 | 47 | 87 | 19 | 9 |
| Phil Dumatrait* |   | sp | 26 | 5.26 | 3 | 4 | 0 | 21 | 11 | 0 | 0 | 78.2 | 82 | 48 | 46 | 42 | 52 | 7 | 7 |
| Chad Durbin | MAD | mr | 30 | 2.87 | 5 | 4 | 1 | 71 | 0 | 0 | 0 | 87.2 | 81 | 33 | 28 | 35 | 63 | 5 | 15 |
| Adam Eaton |   | sp | 30 | 5.80 | 4 | 8 | 0 | 21 | 19 | 0 | 0 | 107.0 | 131 | 71 | 69 | 44 | 57 | 15 | 16 |
| Mike Ekstrom |   | mr | 24 | 7.45 | 0 | 2 | 0 | 8 | 0 | 0 | 0 | 9.2 | 14 | 8 | 8 | 7 | 6 | 2 | 2 |
| Scott Elarton |   | mr | 32 | 3.52 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 15.1 | 16 | 7 | 6 | 9 | 15 | 0 | 0 |
| Scott Elbert* |   | mr | 22 | 12.00 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 6.0 | 9 | 8 | 8 | 4 | 8 | 2 | 1 |
| Alan Embree* |   | mr | 38 | 4.96 | 2 | 5 | 0 | 70 | 0 | 0 | 0 | 61.2 | 59 | 36 | 34 | 30 | 57 | 8 | 8 |
| Geno Espineli* |   | mr | 25 | 5.06 | 2 | 0 | 0 | 15 | 0 | 0 | 0 | 16.0 | 17 | 10 | 9 | 8 | 8 | 5 | 4 |
| Shawn Estes* |   | sp | 35 | 4.74 | 2 | 3 | 0 | 9 | 8 | 0 | 0 | 43.2 | 50 | 26 | 23 | 18 | 19 | 6 | 5 |
| Marco Estrada |   | mr | 24 | 7.82 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 12.2 | 17 | 13 | 11 | 5 | 10 | 4 | 0 |
| Dana Eveland* |   | sp | 24 | 4.34 | 9 | 9 | 0 | 29 | 29 | 1 | 0 | 168.0 | 172 | 82 | 81 | 77 | 118 | 10 | 22 |
| Scott Eyre* |   | mr | 36 | 4.21 | 5 | 0 | 0 | 38 | 0 | 0 | 0 | 25.2 | 23 | 12 | 12 | 7 | 32 | 2 | 4 |
| Brian Falkenborg |   | mr | 30 | 5.24 | 2 | 3 | 0 | 25 | 0 | 0 | 0 | 22.1 | 26 | 13 | 13 | 12 | 19 | 4 | 3 |
| Kyle Farnsworth |   | mr | 32 | 4.48 | 2 | 3 | 1 | 61 | 0 | 0 | 0 | 60.1 | 70 | 32 | 30 | 22 | 61 | 15 | 6 |
| Ryan Feierabend* |   | sp | 22 | 7.71 | 1 | 4 | 0 | 8 | 8 | 0 | 0 | 39.2 | 59 | 34 | 34 | 14 | 26 | 7 | 2 |
| Scott Feldman | MID | sp | 25 | 5.29 | 6 | 8 | 0 | 28 | 25 | 0 | 0 | 151.1 | 161 | 103 | 89 | 56 | 74 | 22 | 24 |
| Pedro Feliciano* | MAD | mr | 31 | 4.05 | 3 | 4 | 2 | 86 | 0 | 0 | 0 | 53.1 | 57 | 24 | 24 | 26 | 50 | 7 | 9 |
| Nelson Figueroa |   | mr | 34 | 4.57 | 3 | 3 | 0 | 16 | 6 | 0 | 0 | 45.1 | 48 | 26 | 23 | 26 | 36 | 3 | 3 |
| Randy Flores* |   | mr | 32 | 5.26 | 1 | 0 | 1 | 43 | 0 | 0 | 0 | 25.2 | 34 | 16 | 15 | 20 | 17 | 2 | 1 |
| Gavin Floyd | TON | sp | 25 | 3.84 | 17 | 8 | 0 | 33 | 33 | 1 | 0 | 206.1 | 190 | 107 | 88 | 70 | 145 | 30 | 17 |
| Josh Fogg |   | sp | 31 | 7.58 | 2 | 7 | 0 | 22 | 14 | 0 | 0 | 78.1 | 97 | 69 | 66 | 27 | 45 | 17 | 8 |
| Casey Fossum* |   | mr | 30 | 5.66 | 3 | 1 | 0 | 31 | 0 | 0 | 0 | 41.1 | 44 | 26 | 26 | 18 | 28 | 4 | 7 |
| Keith Foulke |   | mr | 35 | 4.06 | 0 | 3 | 1 | 31 | 0 | 0 | 0 | 31.0 | 28 | 14 | 14 | 13 | 23 | 7 | 1 |
| Chad Fox |   | mr | 37 | 5.40 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 3.1 | 2 | 2 | 2 | 3 | 1 | 1 | 0 |
| Jeff Francis* |   | sp | 27 | 5.01 | 4 | 10 | 0 | 24 | 24 | 0 | 0 | 143.2 | 164 | 84 | 80 | 49 | 94 | 21 | 8 |
| Frank Francisco | EDG | mr | 28 | 3.13 | 3 | 5 | 5 | 58 | 0 | 0 | 0 | 63.1 | 47 | 24 | 22 | 26 | 83 | 7 | 0 |
| Ryan Franklin |   | mr | 35 | 3.55 | 6 | 6 | 17 | 74 | 0 | 0 | 0 | 78.2 | 86 | 34 | 31 | 30 | 51 | 10 | 7 |
| Jason Frasor | MID | mr | 30 | 4.18 | 1 | 2 | 0 | 49 | 0 | 0 | 0 | 47.1 | 36 | 23 | 22 | 32 | 42 | 4 | 1 |
| Brian Fuentes* | CCL | cl | 32 | 2.73 | 1 | 5 | 30 | 67 | 0 | 0 | 0 | 62.2 | 47 | 22 | 19 | 22 | 82 | 3 | 1 |
| Kazuo Fukumori |   | mr | 31 | 20.25 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 11 | 9 | 9 | 4 | 1 | 2 | 1 |
| Jeff Fulchino |   | mr | 28 | 9.00 | 0 | 1 | 0 | 12 | 0 | 0 | 0 | 14.0 | 21 | 15 | 14 | 8 | 12 | 2 | 1 |
| Kason Gabbard* |   | sp | 26 | 4.82 | 2 | 3 | 0 | 12 | 12 | 0 | 0 | 56.0 | 64 | 36 | 30 | 39 | 33 | 5 | 12 |
| Eric Gagne |   | mr | 32 | 5.44 | 4 | 3 | 10 | 50 | 0 | 0 | 0 | 46.1 | 46 | 28 | 28 | 22 | 38 | 11 | 6 |
| Armando Galarraga |   | sp | 26 | 3.73 | 13 | 7 | 0 | 30 | 28 | 0 | 0 | 178.2 | 152 | 83 | 74 | 61 | 126 | 28 | 16 |
| Sean Gallagher |   | sp | 22 | 5.15 | 5 | 7 | 0 | 23 | 21 | 0 | 0 | 115.1 | 118 | 73 | 66 | 58 | 103 | 13 | 6 |
| Yovani Gallardo | LON | sp | 22 | 1.88 | 0 | 0 | 0 | 4 | 4 | 0 | 0 | 24.0 | 22 | 5 | 5 | 8 | 20 | 3 | 2 |
| Freddy Garcia |   | sp | 32 | 4.20 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 15.0 | 11 | 8 | 7 | 6 | 12 | 3 | 1 |
| Jaime Garcia* |   | mr | 21 | 5.63 | 1 | 1 | 0 | 10 | 1 | 0 | 0 | 16.0 | 14 | 10 | 10 | 8 | 8 | 4 | 2 |
| Lee Gardner |   | mr | 33 | 10.80 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 6.2 | 14 | 8 | 8 | 4 | 4 | 2 | 0 |
| Jon Garland |   | sp | 28 | 4.90 | 14 | 8 | 0 | 32 | 32 | 1 | 0 | 196.2 | 237 | 116 | 107 | 59 | 90 | 23 | 25 |
| Matt Garza | GEO | sp | 24 | 3.70 | 11 | 9 | 0 | 30 | 30 | 3 | 2 | 184.2 | 170 | 83 | 76 | 59 | 128 | 19 | 22 |
| Chad Gaudin |   | mr | 25 | 4.40 | 9 | 5 | 0 | 50 | 6 | 0 | 0 | 90.0 | 92 | 50 | 44 | 27 | 71 | 11 | 9 |
| Geoff Geary | TON | mr | 31 | 2.53 | 2 | 3 | 0 | 55 | 0 | 0 | 0 | 64.0 | 45 | 18 | 18 | 28 | 45 | 3 | 5 |
| Josh Geer |   | sp | 25 | 2.67 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 27.0 | 29 | 8 | 8 | 9 | 16 | 2 | 1 |
| Franklyn German |   | mr | 28 | 2.08 | 1 | 3 | 0 | 17 | 0 | 0 | 0 | 21.2 | 18 | 5 | 5 | 13 | 15 | 0 | 1 |
| Justin Germano |   | sp | 25 | 5.98 | 0 | 3 | 0 | 12 | 6 | 0 | 0 | 43.2 | 54 | 31 | 29 | 13 | 17 | 8 | 6 |
| Dan Giese | BON | mr | 31 | 3.53 | 1 | 3 | 0 | 20 | 3 | 0 | 0 | 43.1 | 39 | 22 | 17 | 14 | 29 | 3 | 0 |
| Matt Ginter |   | sp | 30 | 5.14 | 1 | 3 | 0 | 4 | 4 | 0 | 0 | 21.0 | 25 | 12 | 12 | 3 | 12 | 3 | 4 |
| Tom Glavine* |   | sp | 42 | 5.54 | 2 | 4 | 0 | 13 | 13 | 0 | 0 | 63.1 | 67 | 40 | 39 | 37 | 37 | 11 | 8 |
| Gary Glover |   | mr | 31 | 5.30 | 2 | 3 | 0 | 47 | 0 | 0 | 0 | 54.1 | 64 | 33 | 32 | 22 | 37 | 7 | 8 |
| Jimmy Gobble* |   | mr | 26 | 8.81 | 0 | 2 | 1 | 39 | 0 | 0 | 0 | 31.2 | 39 | 31 | 31 | 23 | 27 | 5 | 0 |
| Edgar Gonzalez |   | mr | 25 | 6.00 | 1 | 3 | 0 | 17 | 6 | 0 | 0 | 48.0 | 58 | 34 | 32 | 21 | 32 | 8 | 5 |
| Enrique Gonzalez |   | mr | 25 | 10.80 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 4 | 4 | 4 | 2 | 1 | 0 | 1 |
| Gio Gonzalez* |   | sp | 22 | 7.68 | 1 | 4 | 0 | 10 | 7 | 0 | 0 | 34.0 | 32 | 34 | 29 | 25 | 34 | 9 | 1 |
| Mike Gonzalez* |   | cl | 30 | 4.28 | 0 | 3 | 14 | 36 | 0 | 0 | 0 | 33.2 | 26 | 21 | 16 | 14 | 44 | 6 | 2 |
| Brian Gordon |   | mr | 29 | 2.25 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.0 | 4 | 1 | 1 | 0 | 1 | 0 | 0 |
| Tom Gordon |   | mr | 40 | 5.16 | 5 | 4 | 2 | 34 | 0 | 0 | 0 | 29.2 | 31 | 19 | 17 | 17 | 26 | 3 | 0 |
| Tom Gorzelanny* |   | sp | 25 | 6.66 | 6 | 9 | 0 | 21 | 21 | 0 | 0 | 105.1 | 120 | 79 | 78 | 70 | 67 | 20 | 16 |
| John Grabow* | TON | mr | 29 | 2.84 | 6 | 3 | 4 | 74 | 0 | 0 | 0 | 76.0 | 60 | 25 | 24 | 37 | 62 | 9 | 7 |
| Jeff Gray |   | mr | 26 | 7.71 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.2 | 8 | 4 | 4 | 1 | 4 | 1 | 0 |
| Sean Green |   | mr | 29 | 4.67 | 4 | 5 | 1 | 72 | 0 | 0 | 0 | 79.0 | 80 | 47 | 41 | 36 | 62 | 3 | 7 |
| Kevin Gregg | BT | cl | 30 | 3.41 | 7 | 8 | 29 | 72 | 0 | 0 | 0 | 68.2 | 51 | 30 | 26 | 37 | 58 | 3 | 4 |
| Zack Greinke | COP | sp | 24 | 3.47 | 13 | 10 | 0 | 32 | 32 | 1 | 0 | 202.1 | 202 | 87 | 78 | 56 | 183 | 21 | 15 |
| Jason Grilli | COP | mr | 31 | 3.00 | 3 | 3 | 1 | 60 | 0 | 0 | 0 | 75.0 | 67 | 27 | 25 | 38 | 69 | 2 | 8 |
| Eddie Guardado* |   | mr | 37 | 4.15 | 4 | 4 | 4 | 65 | 0 | 0 | 0 | 56.1 | 50 | 26 | 26 | 19 | 33 | 4 | 7 |
| Matt Guerrier | MID | mr | 29 | 5.19 | 6 | 9 | 1 | 76 | 0 | 0 | 0 | 76.1 | 84 | 47 | 44 | 37 | 59 | 12 | 3 |
| Carlos Guevara |   | mr | 26 | 5.84 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 12.1 | 13 | 9 | 8 | 9 | 11 | 2 | 1 |
| Jeremy Guthrie | MID | sp | 29 | 3.63 | 10 | 12 | 0 | 30 | 30 | 1 | 0 | 190.2 | 176 | 82 | 77 | 58 | 120 | 24 | 17 |
| Angel Guzman |   | mr | 26 | 5.59 | 0 | 0 | 0 | 6 | 1 | 0 | 0 | 9.2 | 10 | 6 | 6 | 4 | 10 | 1 | 0 |
| Charlie Haeger |   | mr | 24 | 16.62 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 8 | 10 | 8 | 5 | 4 | 2 | 0 |
| Roy Halladay | ROK | sp | 31 | 2.78 | 20 | 11 | 0 | 34 | 33 | 9 | 2 | 246.0 | 220 | 88 | 76 | 39 | 206 | 18 | 21 |
| Cole Hamels* | BT | sp | 24 | 3.09 | 14 | 10 | 0 | 33 | 33 | 2 | 2 | 227.1 | 193 | 89 | 78 | 53 | 196 | 28 | 15 |
| Jason Hammel | EDG | mr | 25 | 4.60 | 4 | 4 | 2 | 40 | 5 | 0 | 0 | 78.1 | 83 | 45 | 40 | 35 | 44 | 11 | 7 |
| Justin Hampson* |   | mr | 28 | 2.93 | 2 | 1 | 0 | 35 | 0 | 0 | 0 | 30.2 | 31 | 11 | 10 | 10 | 19 | 1 | 6 |
| Mike Hampton* |   | sp | 35 | 4.85 | 3 | 4 | 0 | 13 | 13 | 0 | 0 | 78.0 | 83 | 45 | 42 | 28 | 38 | 10 | 12 |
| Joel Hanrahan | CCL | mr | 26 | 3.95 | 6 | 3 | 9 | 69 | 0 | 0 | 0 | 84.1 | 73 | 40 | 37 | 42 | 93 | 9 | 5 |
| Devern Hansack |   | mr | 30 | 4.05 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 6.2 | 6 | 5 | 3 | 1 | 5 | 0 | 1 |
| Craig Hansen |   | mr | 24 | 6.22 | 2 | 7 | 3 | 48 | 0 | 0 | 0 | 46.1 | 40 | 37 | 32 | 43 | 32 | 3 | 3 |
| J.A. Happ* |   | sp | 25 | 3.69 | 1 | 0 | 0 | 8 | 4 | 0 | 0 | 31.2 | 28 | 13 | 13 | 14 | 26 | 3 | 0 |
| Aaron Harang | GEO | sp | 30 | 4.78 | 6 | 17 | 0 | 30 | 29 | 1 | 1 | 184.1 | 205 | 104 | 98 | 50 | 153 | 35 | 12 |
| Rich Harden | COP | sp | 26 | 2.07 | 10 | 2 | 0 | 25 | 25 | 0 | 0 | 148.0 | 96 | 38 | 34 | 61 | 181 | 11 | 2 |
| Dan Haren | LON | sp | 27 | 3.33 | 16 | 8 | 0 | 33 | 33 | 1 | 1 | 216.0 | 204 | 86 | 80 | 40 | 206 | 19 | 12 |
| Matt Harrison* |   | sp | 22 | 5.49 | 9 | 3 | 0 | 15 | 15 | 1 | 1 | 83.2 | 100 | 57 | 51 | 31 | 42 | 12 | 10 |
| Kevin Hart |   | mr | 25 | 6.51 | 2 | 2 | 0 | 21 | 0 | 0 | 0 | 27.2 | 39 | 24 | 20 | 18 | 23 | 2 | 2 |
| LaTroy Hawkins |   | mr | 35 | 3.92 | 3 | 1 | 1 | 57 | 0 | 0 | 0 | 62.0 | 53 | 29 | 27 | 22 | 48 | 3 | 4 |
| Dirk Hayhurst |   | mr | 27 | 9.72 | 0 | 2 | 0 | 10 | 3 | 0 | 0 | 16.2 | 27 | 18 | 18 | 10 | 14 | 2 | 2 |
| Aaron Heilman |   | mr | 29 | 5.21 | 3 | 8 | 3 | 78 | 0 | 0 | 0 | 76.0 | 75 | 48 | 44 | 46 | 80 | 10 | 1 |
| Mark Hendrickson* |   | sp | 34 | 5.45 | 7 | 8 | 0 | 36 | 19 | 0 | 0 | 133.2 | 148 | 87 | 81 | 48 | 81 | 17 | 9 |
| Sean Henn* |   | mr | 27 | 7.71 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 9.1 | 11 | 8 | 8 | 9 | 9 | 1 | 1 |
| Brad Hennessey |   | mr | 28 | 7.81 | 1 | 2 | 0 | 17 | 4 | 1 | 0 | 40.1 | 63 | 35 | 35 | 15 | 21 | 8 | 0 |
| Clay Hensley |   | mr | 28 | 5.31 | 1 | 2 | 0 | 32 | 1 | 0 | 0 | 39.0 | 36 | 27 | 23 | 25 | 26 | 2 | 6 |
| Matt Herges |   | mr | 38 | 5.04 | 3 | 4 | 0 | 58 | 0 | 0 | 0 | 64.1 | 79 | 40 | 36 | 24 | 46 | 5 | 7 |
| Felix Hernandez | ROK | sp | 22 | 3.45 | 9 | 11 | 0 | 31 | 31 | 2 | 0 | 200.2 | 198 | 85 | 77 | 80 | 175 | 17 | 28 |
| Fernando Hernandez |   | mr | 23 | 18.00 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 3.0 | 4 | 6 | 6 | 5 | 2 | 0 | 0 |
| Livan Hernandez |   | sp | 33 | 6.05 | 13 | 11 | 0 | 31 | 31 | 2 | 0 | 180.0 | 257 | 129 | 121 | 43 | 67 | 25 | 24 |
| Runelvys Hernandez |   | sp | 30 | 8.38 | 0 | 3 | 0 | 4 | 4 | 0 | 0 | 19.1 | 32 | 19 | 18 | 11 | 15 | 4 | 3 |
| Danny Herrera* |   | mr | 23 | 7.36 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 7.1 | 10 | 7 | 6 | 3 | 8 | 1 | 0 |
| Yoslan Herrera |   | sp | 27 | 9.82 | 1 | 1 | 0 | 5 | 5 | 0 | 0 | 18.1 | 35 | 20 | 20 | 12 | 10 | 1 | 3 |
| Rich Hill* |   | sp | 28 | 4.12 | 1 | 0 | 0 | 5 | 5 | 0 | 0 | 19.2 | 13 | 9 | 9 | 18 | 15 | 2 | 1 |
| Shawn Hill |   | sp | 27 | 5.83 | 1 | 5 | 0 | 12 | 12 | 0 | 0 | 63.1 | 88 | 47 | 41 | 23 | 39 | 5 | 5 |
| Mike Hinckley* |   | mr | 25 | 0.00 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 13.2 | 8 | 1 | 0 | 3 | 9 | 0 | 2 |
| Alex Hinshaw* |   | mr | 25 | 3.40 | 2 | 1 | 0 | 48 | 0 | 0 | 0 | 39.2 | 31 | 16 | 15 | 29 | 47 | 5 | 1 |
| Jason Hirsh |   | mr | 26 | 8.31 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 8.2 | 15 | 10 | 8 | 4 | 6 | 3 | 0 |
| Luke Hochevar |   | sp | 24 | 5.51 | 6 | 12 | 0 | 22 | 22 | 0 | 0 | 129.0 | 143 | 84 | 79 | 47 | 72 | 12 | 15 |
| Trevor Hoffman | Pal | cl | 40 | 3.77 | 3 | 6 | 30 | 48 | 0 | 0 | 0 | 45.1 | 38 | 19 | 19 | 9 | 46 | 8 | 2 |
| J.P. Howell* | MID | mr | 25 | 2.22 | 6 | 1 | 3 | 64 | 0 | 0 | 0 | 89.1 | 62 | 29 | 22 | 39 | 92 | 6 | 7 |
| Bob Howry | WIZ | mr | 34 | 5.35 | 7 | 5 | 1 | 72 | 0 | 0 | 0 | 70.2 | 90 | 44 | 42 | 13 | 59 | 13 | 6 |
| Tim Hudson | GEO | sp | 32 | 3.17 | 11 | 7 | 0 | 23 | 22 | 1 | 1 | 142.0 | 125 | 53 | 50 | 40 | 85 | 11 | 16 |
| Phil Hughes | COP | sp | 22 | 6.62 | 0 | 4 | 0 | 8 | 8 | 0 | 0 | 34.0 | 43 | 26 | 25 | 15 | 23 | 3 | 3 |
| Philip Humber |   | mr | 25 | 4.63 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 11.2 | 11 | 6 | 6 | 5 | 6 | 4 | 2 |
| Tommy Hunter |   | sp | 21 | 16.36 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 11.0 | 23 | 20 | 20 | 3 | 9 | 4 | 0 |
| Eric Hurley |   | sp | 22 | 5.47 | 1 | 2 | 0 | 5 | 5 | 0 | 0 | 24.2 | 26 | 15 | 15 | 9 | 13 | 5 | 1 |
| Kei Igawa* |   | sp | 28 | 13.50 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 4.0 | 13 | 6 | 6 | 0 | 0 | 0 | 1 |
| Jason Isringhausen |   | cl | 35 | 5.70 | 1 | 5 | 12 | 42 | 0 | 0 | 0 | 42.2 | 48 | 28 | 27 | 22 | 36 | 5 | 3 |
| Edwin Jackson |   | sp | 24 | 4.42 | 14 | 11 | 0 | 32 | 31 | 0 | 0 | 183.1 | 199 | 91 | 90 | 77 | 108 | 23 | 27 |
| Zach Jackson* |   | sp | 25 | 5.55 | 2 | 3 | 0 | 11 | 9 | 0 | 0 | 58.1 | 69 | 38 | 36 | 16 | 31 | 7 | 9 |
| Chuck James* |   | sp | 26 | 9.10 | 2 | 5 | 0 | 7 | 7 | 0 | 0 | 29.2 | 36 | 30 | 30 | 20 | 22 | 10 | 2 |
| Bobby Jenks | OTR | cl | 27 | 2.63 | 3 | 1 | 30 | 57 | 0 | 0 | 0 | 61.2 | 51 | 18 | 18 | 17 | 38 | 3 | 9 |
| Jason Jennings |   | sp | 29 | 8.56 | 0 | 5 | 0 | 6 | 6 | 0 | 0 | 27.1 | 35 | 27 | 26 | 18 | 12 | 8 | 2 |
| Kevin Jepsen |   | mr | 23 | 4.32 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 8.1 | 8 | 5 | 4 | 4 | 7 | 0 | 1 |
| Cesar Jimenez* |   | mr | 23 | 3.41 | 0 | 2 | 0 | 31 | 2 | 0 | 0 | 34.1 | 32 | 13 | 13 | 13 | 26 | 2 | 3 |
| Kelvin Jimenez |   | mr | 27 | 5.63 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 24.0 | 28 | 15 | 15 | 15 | 11 | 5 | 3 |
| Ubaldo Jimenez | TON | sp | 24 | 3.99 | 12 | 12 | 0 | 34 | 34 | 1 | 0 | 198.2 | 182 | 97 | 88 | 103 | 172 | 11 | 18 |
| Jason Johnson |   | mr | 34 | 5.22 | 1 | 2 | 0 | 16 | 2 | 0 | 0 | 29.1 | 32 | 19 | 17 | 12 | 20 | 5 | 4 |
| Jim Johnson | GEO | mr | 25 | 2.23 | 2 | 4 | 1 | 54 | 0 | 0 | 0 | 68.2 | 54 | 18 | 17 | 28 | 38 | 0 | 14 |
| Josh Johnson | LON | sp | 24 | 3.61 | 7 | 1 | 0 | 14 | 14 | 1 | 0 | 87.1 | 91 | 36 | 35 | 27 | 77 | 7 | 12 |
| Randy Johnson* | ROK | sp | 44 | 3.91 | 11 | 10 | 0 | 30 | 30 | 2 | 0 | 184.0 | 184 | 92 | 80 | 44 | 173 | 24 | 8 |
| Todd Jones |   | cl | 40 | 4.97 | 4 | 1 | 18 | 45 | 0 | 0 | 0 | 41.2 | 50 | 30 | 23 | 18 | 14 | 5 | 6 |
| Jorge Julio |   | mr | 29 | 3.60 | 3 | 0 | 0 | 27 | 0 | 0 | 0 | 30.0 | 27 | 12 | 12 | 19 | 34 | 3 | 3 |
| Jair Jurrjens | WIZ | sp | 22 | 3.68 | 13 | 10 | 0 | 31 | 31 | 0 | 0 | 188.1 | 188 | 87 | 77 | 70 | 139 | 11 | 16 |
| Jeff Karstens |   | sp | 25 | 4.03 | 2 | 6 | 0 | 9 | 9 | 1 | 1 | 51.1 | 56 | 32 | 23 | 13 | 23 | 7 | 5 |
| Scott Kazmir* | GEO | sp | 24 | 3.49 | 12 | 8 | 0 | 27 | 27 | 0 | 0 | 152.1 | 123 | 61 | 59 | 70 | 166 | 23 | 6 |
| Kyle Kendrick |   | sp | 23 | 5.49 | 11 | 9 | 0 | 31 | 30 | 0 | 0 | 155.2 | 194 | 103 | 95 | 57 | 68 | 23 | 8 |
| Ian Kennedy |   | sp | 23 | 8.17 | 0 | 4 | 0 | 10 | 9 | 0 | 0 | 39.2 | 50 | 37 | 36 | 26 | 27 | 5 | 1 |
| Logan Kensing |   | mr | 25 | 4.23 | 3 | 1 | 0 | 48 | 0 | 0 | 0 | 55.1 | 50 | 26 | 26 | 33 | 55 | 7 | 3 |
| Clayton Kershaw* | MUL | sp | 20 | 4.26 | 5 | 5 | 0 | 22 | 21 | 0 | 0 | 107.2 | 109 | 51 | 51 | 52 | 100 | 11 | 12 |
| Ray King* |   | mr | 34 | 5.68 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 6.1 | 9 | 4 | 4 | 4 | 1 | 1 | 1 |
| Josh Kinney |   | mr | 29 | 0.00 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 7.0 | 3 | 0 | 0 | 1 | 8 | 0 | 0 |
| Brandon Knight |   | sp | 32 | 5.25 | 1 | 0 | 0 | 4 | 2 | 0 | 0 | 12.0 | 14 | 7 | 7 | 7 | 10 | 0 | 1 |
| Masa Kobayashi |   | mr | 34 | 4.53 | 4 | 5 | 6 | 57 | 0 | 0 | 0 | 55.2 | 65 | 30 | 28 | 14 | 35 | 8 | 5 |
| Bobby Korecky |   | mr | 28 | 4.58 | 2 | 0 | 0 | 16 | 0 | 0 | 0 | 17.2 | 19 | 9 | 9 | 8 | 6 | 2 | 5 |
| Eddie Kunz |   | mr | 22 | 13.50 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 2.2 | 5 | 4 | 4 | 1 | 1 | 1 | 1 |
| Hong-Chih Kuo* | Pal | mr | 26 | 2.14 | 5 | 3 | 1 | 42 | 3 | 0 | 0 | 80.0 | 60 | 21 | 19 | 21 | 96 | 4 | 3 |
| Hiroki Kuroda | WIZ | sp | 33 | 3.73 | 9 | 10 | 0 | 31 | 31 | 2 | 2 | 183.1 | 181 | 85 | 76 | 42 | 116 | 13 | 10 |
| John Lackey | COP | sp | 29 | 3.75 | 12 | 5 | 0 | 24 | 24 | 3 | 0 | 163.1 | 161 | 71 | 68 | 40 | 130 | 26 | 21 |
| Aaron Laffey* |   | sp | 23 | 4.23 | 5 | 7 | 0 | 16 | 16 | 0 | 0 | 93.2 | 103 | 52 | 44 | 31 | 43 | 10 | 17 |
| Chris Lambert |   | mr | 25 | 5.66 | 1 | 2 | 0 | 8 | 3 | 0 | 0 | 20.2 | 31 | 18 | 13 | 7 | 15 | 3 | 1 |
| John Lannan* |   | sp | 23 | 3.91 | 9 | 15 | 0 | 31 | 31 | 0 | 0 | 182.0 | 172 | 89 | 79 | 72 | 117 | 23 | 19 |
| Brandon League |   | mr | 25 | 2.18 | 1 | 2 | 1 | 31 | 0 | 0 | 0 | 33.0 | 28 | 9 | 8 | 15 | 23 | 2 | 5 |
| Wade LeBlanc* |   | sp | 23 | 8.02 | 1 | 3 | 0 | 5 | 4 | 0 | 0 | 21.1 | 29 | 19 | 19 | 15 | 14 | 7 | 2 |
| Wil Ledezma* |   | mr | 27 | 4.17 | 0 | 2 | 0 | 28 | 6 | 0 | 0 | 58.1 | 51 | 29 | 27 | 41 | 53 | 4 | 3 |
| Cliff Lee* | MID | sp | 29 | 2.54 | 22 | 3 | 0 | 31 | 31 | 4 | 2 | 223.1 | 214 | 68 | 63 | 34 | 170 | 12 | 27 |
| Jon Lester* | EDG | sp | 24 | 3.21 | 16 | 6 | 0 | 33 | 33 | 2 | 2 | 210.1 | 202 | 78 | 75 | 66 | 152 | 14 | 27 |
| Jensen Lewis |   | cl | 24 | 3.82 | 0 | 4 | 13 | 51 | 0 | 0 | 0 | 66.0 | 68 | 29 | 28 | 27 | 52 | 8 | 4 |
| Scott Lewis* |   | sp | 24 | 2.63 | 4 | 0 | 0 | 4 | 4 | 0 | 0 | 24.0 | 20 | 9 | 7 | 6 | 15 | 4 | 2 |
| Brad Lidge | Pal | cl | 31 | 1.95 | 2 | 0 | 41 | 72 | 0 | 0 | 0 | 69.1 | 50 | 17 | 15 | 35 | 92 | 2 | 3 |
| Jon Lieber |   | mr | 38 | 4.05 | 2 | 3 | 0 | 26 | 1 | 0 | 0 | 46.2 | 59 | 24 | 21 | 6 | 27 | 10 | 6 |
| Ted Lilly* | OTR | sp | 32 | 4.09 | 17 | 9 | 0 | 34 | 34 | 0 | 0 | 204.2 | 187 | 96 | 93 | 64 | 184 | 32 | 8 |
| Tim Lincecum | WIZ | sp | 24 | 2.62 | 18 | 5 | 0 | 34 | 33 | 2 | 1 | 227.0 | 182 | 72 | 66 | 84 | 265 | 11 | 23 |
| Mike Lincoln |   | mr | 33 | 4.48 | 2 | 5 | 0 | 64 | 0 | 0 | 0 | 70.1 | 66 | 37 | 35 | 24 | 57 | 10 | 6 |
| Matt Lindstrom |   | mr | 28 | 3.14 | 3 | 3 | 5 | 66 | 0 | 0 | 0 | 57.1 | 57 | 21 | 20 | 26 | 43 | 1 | 7 |
| Scott Linebrink | EDG | mr | 31 | 3.69 | 2 | 2 | 1 | 50 | 0 | 0 | 0 | 46.1 | 41 | 20 | 19 | 9 | 40 | 8 | 4 |
| Francisco Liriano* | ROK | sp | 24 | 3.91 | 6 | 4 | 0 | 14 | 14 | 0 | 0 | 76.0 | 74 | 40 | 33 | 32 | 67 | 7 | 6 |
| Jesse Litsch | EDG | sp | 23 | 3.58 | 13 | 9 | 0 | 29 | 28 | 2 | 2 | 176.0 | 178 | 79 | 70 | 39 | 99 | 20 | 11 |
| Wes Littleton |   | mr | 25 | 6.00 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 18.0 | 18 | 12 | 12 | 8 | 14 | 1 | 4 |
| Radhames Liz |   | sp | 25 | 6.72 | 6 | 6 | 0 | 17 | 17 | 0 | 0 | 84.1 | 99 | 67 | 63 | 51 | 57 | 16 | 7 |
| Esteban Loaiza |   | mr | 36 | 5.33 | 1 | 2 | 0 | 10 | 3 | 0 | 0 | 27.0 | 27 | 17 | 16 | 5 | 10 | 4 | 0 |
| Kameron Loe |   | mr | 26 | 3.23 | 1 | 0 | 0 | 14 | 0 | 0 | 0 | 30.2 | 36 | 18 | 11 | 8 | 20 | 3 | 2 |
| Adam Loewen* |   | sp | 24 | 8.02 | 0 | 2 | 0 | 7 | 4 | 0 | 0 | 21.1 | 25 | 19 | 19 | 18 | 14 | 5 | 1 |
| Boone Logan* |   | mr | 23 | 5.95 | 2 | 3 | 0 | 55 | 0 | 0 | 0 | 42.1 | 57 | 31 | 28 | 14 | 42 | 7 | 2 |
| Kyle Lohse | CCL | sp | 29 | 3.78 | 15 | 6 | 0 | 33 | 33 | 0 | 0 | 200.0 | 211 | 88 | 84 | 49 | 119 | 18 | 17 |
| Braden Looper |   | sp | 33 | 4.16 | 12 | 14 | 0 | 33 | 33 | 1 | 1 | 199.0 | 216 | 101 | 92 | 45 | 108 | 25 | 23 |
| Aquilino Lopez |   | mr | 33 | 3.55 | 4 | 1 | 0 | 48 | 0 | 0 | 0 | 78.2 | 86 | 33 | 31 | 22 | 61 | 9 | 5 |
| Javier Lopez* | OTR | mr | 30 | 2.43 | 2 | 0 | 0 | 70 | 0 | 0 | 0 | 59.1 | 53 | 18 | 16 | 27 | 38 | 4 | 11 |
| Shane Loux |   | mr | 28 | 2.81 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 16.0 | 16 | 6 | 5 | 2 | 4 | 1 | 3 |
| Derek Lowe | BON | sp | 35 | 3.24 | 14 | 11 | 0 | 34 | 34 | 1 | 0 | 211.0 | 194 | 84 | 76 | 45 | 147 | 14 | 19 |
| Mark Lowe |   | mr | 25 | 5.37 | 1 | 5 | 1 | 57 | 0 | 0 | 0 | 63.2 | 78 | 44 | 38 | 34 | 55 | 6 | 8 |
| Devon Lowery |   | mr | 25 | 10.38 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.1 | 6 | 5 | 5 | 2 | 6 | 2 | 0 |
| Brandon Lyon | Pal | cl | 28 | 4.70 | 3 | 5 | 26 | 61 | 0 | 0 | 0 | 59.1 | 75 | 34 | 31 | 13 | 44 | 7 | 3 |
| Mike MacDougal |   | mr | 31 | 2.12 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 17.0 | 16 | 4 | 4 | 12 | 12 | 0 | 3 |
| Greg Maddux | Pal | sp | 42 | 4.22 | 8 | 13 | 0 | 33 | 33 | 0 | 0 | 194.0 | 204 | 105 | 91 | 30 | 98 | 21 | 16 |
| Warner Madrigal |   | mr | 24 | 4.75 | 0 | 2 | 1 | 31 | 1 | 0 | 0 | 36.0 | 36 | 22 | 19 | 14 | 22 | 4 | 3 |
| Ryan Madson | CCL | mr | 27 | 3.05 | 4 | 2 | 1 | 76 | 0 | 0 | 0 | 82.2 | 79 | 29 | 28 | 23 | 67 | 6 | 7 |
| Ron Mahay* |   | mr | 37 | 3.48 | 5 | 0 | 0 | 57 | 0 | 0 | 0 | 64.2 | 61 | 27 | 25 | 29 | 49 | 6 | 6 |
| Paul Maholm* | MAD | sp | 26 | 3.71 | 9 | 9 | 0 | 31 | 31 | 1 | 0 | 206.1 | 201 | 89 | 85 | 63 | 139 | 21 | 27 |
| John Maine | BT | sp | 27 | 4.18 | 10 | 8 | 0 | 25 | 25 | 0 | 0 | 140.0 | 122 | 70 | 65 | 67 | 122 | 16 | 5 |
| Gary Majewski |   | mr | 28 | 6.52 | 1 | 0 | 0 | 37 | 0 | 0 | 0 | 40.0 | 61 | 31 | 29 | 15 | 27 | 6 | 6 |
| Charlie Manning* |   | mr | 29 | 5.14 | 1 | 3 | 0 | 57 | 0 | 0 | 0 | 42.0 | 35 | 25 | 24 | 31 | 37 | 8 | 3 |
| Shaun Marcum | COP | sp | 26 | 3.39 | 9 | 7 | 0 | 25 | 25 | 0 | 0 | 151.1 | 126 | 60 | 57 | 50 | 123 | 21 | 8 |
| Carlos Marmol | WIZ | mr | 25 | 2.68 | 2 | 4 | 7 | 82 | 0 | 0 | 0 | 87.1 | 40 | 30 | 26 | 41 | 114 | 10 | 2 |
| Jason Marquis | CCL | sp | 29 | 4.53 | 11 | 9 | 0 | 29 | 28 | 0 | 0 | 167.0 | 172 | 87 | 84 | 70 | 91 | 15 | 20 |
| Sean Marshall* | LON | mr | 25 | 3.86 | 3 | 5 | 1 | 34 | 7 | 0 | 0 | 65.1 | 60 | 28 | 28 | 23 | 58 | 9 | 1 |
| Damaso Marte* | WIZ | mr | 33 | 4.02 | 5 | 3 | 5 | 72 | 0 | 0 | 0 | 65.0 | 52 | 29 | 29 | 26 | 71 | 5 | 2 |
| Pedro Martinez |   | sp | 36 | 5.61 | 5 | 6 | 0 | 20 | 20 | 0 | 0 | 109.0 | 127 | 70 | 68 | 44 | 87 | 19 | 7 |
| Shairon Martis |   | sp | 21 | 5.66 | 1 | 3 | 0 | 5 | 4 | 0 | 0 | 20.2 | 18 | 14 | 13 | 12 | 23 | 5 | 1 |
| Nick Masset | GEO | mr | 26 | 3.92 | 2 | 0 | 1 | 42 | 1 | 0 | 0 | 62.0 | 71 | 32 | 27 | 26 | 43 | 7 | 13 |
| Justin Masterson | OTR | mr | 23 | 3.16 | 6 | 5 | 0 | 36 | 9 | 0 | 0 | 88.1 | 68 | 31 | 31 | 40 | 68 | 10 | 16 |
| Tom Mastny |   | mr | 27 | 10.80 | 2 | 2 | 0 | 14 | 1 | 0 | 0 | 20.0 | 28 | 24 | 24 | 11 | 19 | 6 | 0 |
| Doug Mathis |   | sp | 25 | 6.85 | 2 | 1 | 0 | 8 | 4 | 0 | 0 | 22.1 | 37 | 20 | 17 | 14 | 9 | 3 | 5 |
| Osiris Matos |   | mr | 23 | 4.79 | 1 | 2 | 0 | 20 | 0 | 0 | 0 | 20.2 | 26 | 17 | 11 | 9 | 16 | 3 | 0 |
| Daisuke Matsuzaka | OTR | sp | 27 | 2.90 | 18 | 3 | 0 | 29 | 29 | 0 | 0 | 167.2 | 128 | 58 | 54 | 94 | 154 | 12 | 13 |
| Brandon McCarthy | EDG | sp | 24 | 4.09 | 1 | 1 | 0 | 5 | 5 | 0 | 0 | 22.0 | 20 | 11 | 10 | 8 | 10 | 3 | 2 |
| Kyle McClellan | MAD | mr | 24 | 4.04 | 2 | 7 | 1 | 68 | 0 | 0 | 0 | 75.2 | 79 | 37 | 34 | 26 | 59 | 7 | 8 |
| Seth McClung | EDG | mr | 27 | 4.02 | 6 | 6 | 0 | 37 | 12 | 0 | 0 | 105.1 | 93 | 47 | 47 | 55 | 87 | 10 | 9 |
| Bob McCrory |   | mr | 26 | 15.63 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 6.1 | 10 | 12 | 11 | 8 | 5 | 0 | 0 |
| James McDonald |   | mr | 23 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 1 | 2 | 0 | 0 |
| Dustin McGowan |   | sp | 26 | 4.37 | 6 | 7 | 0 | 19 | 19 | 1 | 0 | 111.1 | 115 | 60 | 54 | 38 | 85 | 9 | 9 |
| Gil Meche | CRH | sp | 29 | 3.98 | 14 | 11 | 0 | 34 | 34 | 0 | 0 | 210.1 | 204 | 98 | 93 | 73 | 183 | 19 | 18 |
| Brandon Medders |   | mr | 28 | 4.58 | 1 | 0 | 0 | 18 | 0 | 0 | 0 | 19.2 | 17 | 11 | 10 | 11 | 8 | 2 | 1 |
| Evan Meek |   | mr | 25 | 6.92 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 13.0 | 11 | 11 | 10 | 12 | 7 | 3 | 3 |
| Jon Meloan |   | mr | 23 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 |
| Luis Mendoza |   | mr | 24 | 8.67 | 3 | 8 | 1 | 25 | 11 | 0 | 0 | 63.1 | 97 | 74 | 61 | 25 | 35 | 7 | 4 |
| Kent Mercker* |   | mr | 40 | 3.29 | 1 | 0 | 0 | 15 | 0 | 0 | 0 | 13.2 | 13 | 5 | 5 | 8 | 6 | 1 | 4 |
| Cla Meredith |   | mr | 25 | 4.09 | 0 | 3 | 0 | 73 | 0 | 0 | 0 | 70.1 | 79 | 34 | 32 | 24 | 49 | 6 | 12 |
| Randy Messenger |   | mr | 26 | 3.55 | 0 | 0 | 1 | 13 | 0 | 0 | 0 | 12.2 | 16 | 5 | 5 | 5 | 7 | 1 | 1 |
| Dan Meyer* |   | mr | 26 | 7.48 | 0 | 4 | 0 | 11 | 4 | 0 | 0 | 27.2 | 35 | 28 | 23 | 14 | 20 | 6 | 1 |
| Kam Mickolio |   | mr | 24 | 5.87 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 7.2 | 8 | 5 | 5 | 4 | 8 | 0 | 0 |
| Jose Mijares* |   | mr | 23 | 0.87 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 10.1 | 3 | 1 | 1 | 0 | 5 | 0 | 0 |
| Andrew Miller* | GEO | sp | 23 | 5.87 | 6 | 10 | 0 | 29 | 20 | 0 | 0 | 107.1 | 120 | 78 | 70 | 56 | 89 | 7 | 9 |
| Jim Miller |   | mr | 26 | 1.17 | 0 | 2 | 1 | 8 | 0 | 0 | 0 | 7.2 | 9 | 3 | 1 | 5 | 8 | 0 | 0 |
| Justin Miller |   | mr | 30 | 4.24 | 4 | 2 | 0 | 46 | 0 | 0 | 0 | 46.2 | 46 | 26 | 22 | 20 | 43 | 4 | 3 |
| Trever Miller* |   | mr | 35 | 4.15 | 2 | 0 | 2 | 68 | 0 | 0 | 0 | 43.1 | 39 | 21 | 20 | 20 | 44 | 2 | 5 |
| Kevin Millwood |   | sp | 33 | 5.07 | 9 | 10 | 0 | 29 | 29 | 3 | 0 | 168.2 | 220 | 104 | 95 | 49 | 125 | 18 | 10 |
| Zach Miner | GEO | mr | 26 | 4.27 | 8 | 5 | 0 | 45 | 13 | 0 | 0 | 118.0 | 118 | 60 | 56 | 46 | 62 | 10 | 10 |
| Pat Misch* |   | mr | 26 | 5.68 | 0 | 3 | 0 | 15 | 7 | 0 | 0 | 52.1 | 56 | 34 | 33 | 15 | 38 | 11 | 2 |
| Garrett Mock | CCL | mr | 25 | 4.17 | 1 | 3 | 0 | 26 | 3 | 0 | 0 | 41.0 | 37 | 20 | 19 | 23 | 46 | 4 | 4 |
| Brian Moehler |   | sp | 36 | 4.56 | 11 | 8 | 0 | 31 | 26 | 0 | 0 | 150.0 | 166 | 79 | 76 | 36 | 82 | 20 | 7 |
| Franklin Morales* |   | sp | 22 | 6.39 | 1 | 2 | 0 | 5 | 5 | 0 | 0 | 25.1 | 28 | 18 | 18 | 17 | 9 | 2 | 2 |
| Juan Morillo |   | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Matt Morris |   | sp | 33 | 9.67 | 0 | 4 | 0 | 5 | 5 | 0 | 0 | 22.1 | 41 | 31 | 24 | 7 | 9 | 6 | 2 |
| Brandon Morrow | CRH | mr | 23 | 3.34 | 3 | 4 | 10 | 45 | 5 | 0 | 0 | 64.2 | 40 | 26 | 24 | 34 | 75 | 10 | 2 |
| Charlie Morton | LON | sp | 24 | 6.15 | 4 | 8 | 0 | 16 | 15 | 0 | 0 | 74.2 | 80 | 56 | 51 | 41 | 48 | 9 | 2 |
| Dustin Moseley |   | sp | 26 | 6.79 | 2 | 4 | 0 | 12 | 10 | 0 | 0 | 50.1 | 70 | 38 | 38 | 20 | 37 | 6 | 3 |
| Guillermo Mota |   | mr | 34 | 4.11 | 5 | 6 | 1 | 58 | 0 | 0 | 0 | 57.0 | 52 | 28 | 26 | 28 | 50 | 7 | 6 |
| Jason Motte |   | mr | 26 | 0.82 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 11.0 | 5 | 2 | 1 | 3 | 16 | 0 | 1 |
| Jamie Moyer* | LON | sp | 45 | 3.71 | 16 | 7 | 0 | 33 | 33 | 0 | 0 | 196.1 | 199 | 85 | 81 | 62 | 123 | 20 | 17 |
| Peter Moylan |   | mr | 29 | 1.59 | 0 | 1 | 1 | 7 | 0 | 0 | 0 | 5.2 | 5 | 1 | 1 | 1 | 5 | 1 | 0 |
| Edward Mujica |   | mr | 24 | 6.75 | 3 | 2 | 0 | 33 | 0 | 0 | 0 | 38.2 | 46 | 29 | 29 | 10 | 27 | 5 | 4 |
| Mark Mulder* |   | mr | 30 | 10.80 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 1.2 | 4 | 2 | 2 | 2 | 2 | 0 | 0 |
| Carlos Muniz |   | mr | 27 | 5.40 | 1 | 1 | 0 | 18 | 0 | 0 | 0 | 23.1 | 24 | 14 | 14 | 7 | 16 | 4 | 1 |
| A.J. Murray* |   | sp | 26 | 3.52 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 7.2 | 12 | 4 | 3 | 3 | 5 | 0 | 1 |
| Neal Musser* |   | mr | 27 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
| Mike Mussina | MID | sp | 39 | 3.37 | 20 | 9 | 0 | 34 | 34 | 0 | 0 | 200.1 | 214 | 85 | 75 | 31 | 150 | 17 | 24 |
| Brett Myers | CRH | sp | 27 | 4.55 | 10 | 13 | 0 | 30 | 30 | 2 | 1 | 190.0 | 197 | 103 | 96 | 65 | 163 | 29 | 18 |
| Joe Nathan | WIZ | cl | 33 | 1.33 | 1 | 2 | 39 | 68 | 0 | 0 | 0 | 67.2 | 43 | 13 | 10 | 18 | 74 | 5 | 7 |
| Joe Nelson | CCL | mr | 33 | 2.00 | 3 | 1 | 1 | 59 | 0 | 0 | 0 | 54.0 | 42 | 16 | 12 | 22 | 60 | 5 | 4 |
| Pat Neshek | BON | mr | 27 | 4.72 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 13.1 | 12 | 7 | 7 | 4 | 15 | 2 | 0 |
| Josh Newman* |   | mr | 26 | 8.62 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 15.2 | 25 | 18 | 15 | 12 | 8 | 4 | 2 |
| Jeff Niemann |   | mr | 25 | 5.06 | 2 | 2 | 0 | 5 | 2 | 0 | 0 | 16.0 | 18 | 12 | 9 | 8 | 14 | 3 | 1 |
| Jonathon Niese* |   | sp | 21 | 7.07 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 14.0 | 20 | 11 | 11 | 8 | 11 | 2 | 1 |
| Fernando Nieve |   | mr | 25 | 8.44 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | 10.2 | 17 | 10 | 10 | 2 | 12 | 2 | 1 |
| Dustin Nippert |   | mr | 27 | 6.40 | 3 | 5 | 0 | 20 | 6 | 0 | 0 | 71.2 | 92 | 52 | 51 | 37 | 55 | 10 | 3 |
| Ricky Nolasco | CCL | sp | 25 | 3.52 | 15 | 8 | 0 | 34 | 32 | 1 | 1 | 212.1 | 192 | 88 | 83 | 42 | 186 | 28 | 11 |
| Hideo Nomo |   | mr | 39 | 18.69 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.1 | 10 | 9 | 9 | 4 | 3 | 3 | 0 |
| Leo Nunez | ROK | mr | 24 | 2.98 | 4 | 1 | 0 | 45 | 0 | 0 | 0 | 48.1 | 45 | 19 | 16 | 15 | 26 | 2 | 5 |
| Vladimir Nunez |   | mr | 33 | 3.86 | 1 | 2 | 0 | 23 | 0 | 0 | 0 | 32.2 | 32 | 14 | 14 | 19 | 24 | 0 | 3 |
| Mike O'Connor* |   | mr | 27 | 13.00 | 1 | 1 | 0 | 5 | 1 | 0 | 0 | 9.0 | 11 | 13 | 13 | 11 | 4 | 3 | 1 |
| Darren O'Day | MID | mr | 25 | 4.57 | 0 | 1 | 0 | 30 | 0 | 0 | 0 | 43.1 | 49 | 24 | 22 | 14 | 29 | 2 | 4 |
| Eric O'Flaherty* |   | mr | 23 | 20.25 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 6.2 | 16 | 15 | 15 | 4 | 4 | 2 | 0 |
| Ross Ohlendorf |   | mr | 25 | 6.46 | 1 | 4 | 0 | 30 | 5 | 0 | 0 | 62.2 | 86 | 49 | 45 | 31 | 49 | 10 | 7 |
| Will Ohman* | MAD | mr | 30 | 3.68 | 4 | 1 | 1 | 83 | 0 | 0 | 0 | 58.2 | 51 | 27 | 24 | 22 | 53 | 3 | 3 |
| Hideki Okajima* | COP | mr | 32 | 2.61 | 3 | 2 | 1 | 64 | 0 | 0 | 0 | 62.0 | 49 | 18 | 18 | 23 | 60 | 6 | 1 |
| Darren Oliver* | GEO | mr | 37 | 2.88 | 7 | 1 | 0 | 54 | 0 | 0 | 0 | 72.0 | 67 | 24 | 23 | 16 | 48 | 5 | 8 |
| Scott Olsen* |   | sp | 24 | 4.20 | 8 | 11 | 0 | 33 | 33 | 0 | 0 | 201.2 | 195 | 106 | 94 | 69 | 113 | 30 | 14 |
| Garrett Olson* |   | sp | 24 | 6.65 | 9 | 10 | 0 | 26 | 26 | 0 | 0 | 132.2 | 168 | 100 | 98 | 62 | 83 | 17 | 11 |
| Franquelis Osoria |   | mr | 26 | 6.08 | 4 | 3 | 0 | 43 | 0 | 0 | 0 | 60.2 | 87 | 43 | 41 | 12 | 31 | 10 | 11 |
| Roy Oswalt | BT | sp | 30 | 3.54 | 17 | 10 | 0 | 32 | 32 | 3 | 2 | 208.2 | 199 | 89 | 82 | 47 | 165 | 23 | 16 |
| Josh Outman* |   | sp | 23 | 4.56 | 1 | 2 | 0 | 6 | 4 | 0 | 0 | 25.2 | 34 | 14 | 13 | 8 | 19 | 1 | 3 |
| Micah Owings | MUL | sp | 25 | 5.93 | 6 | 9 | 0 | 22 | 18 | 0 | 0 | 104.2 | 104 | 73 | 69 | 41 | 87 | 14 | 3 |
| Vicente Padilla |   | sp | 30 | 4.74 | 14 | 8 | 0 | 29 | 29 | 1 | 1 | 171.0 | 185 | 100 | 90 | 65 | 127 | 26 | 21 |
| Matt Palmer |   | sp | 29 | 8.53 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 12.2 | 17 | 13 | 12 | 13 | 3 | 1 | 2 |
| Jonathan Papelbon | BON | cl | 27 | 2.34 | 5 | 4 | 41 | 67 | 0 | 0 | 0 | 69.1 | 58 | 24 | 18 | 8 | 77 | 4 | 3 |
| Mike Parisi |   | mr | 25 | 8.22 | 0 | 4 | 0 | 12 | 2 | 0 | 0 | 23.0 | 37 | 24 | 21 | 15 | 13 | 2 | 0 |
| Chan Ho Park |   | mr | 35 | 3.40 | 4 | 4 | 2 | 54 | 5 | 0 | 0 | 95.1 | 97 | 43 | 36 | 36 | 79 | 12 | 11 |
| Bobby Parnell |   | mr | 23 | 5.40 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 5.0 | 3 | 3 | 3 | 2 | 3 | 0 | 1 |
| Chad Paronto |   | mr | 32 | 4.35 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 10.1 | 11 | 5 | 5 | 2 | 4 | 2 | 3 |
| James Parr |   | sp | 22 | 4.84 | 1 | 0 | 0 | 5 | 5 | 0 | 0 | 22.1 | 29 | 13 | 12 | 9 | 14 | 4 | 2 |
| Manny Parra* |   | sp | 25 | 4.39 | 10 | 8 | 0 | 32 | 29 | 0 | 0 | 166.0 | 181 | 91 | 81 | 75 | 147 | 18 | 18 |
| John Parrish* |   | mr | 30 | 4.04 | 1 | 1 | 0 | 13 | 6 | 0 | 0 | 42.1 | 47 | 19 | 19 | 15 | 21 | 5 | 6 |
| Scott Patterson |   | mr | 29 | 1.93 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.2 | 2 | 1 | 1 | 6 | 7 | 0 | 0 |
| David Pauley |   | mr | 25 | 11.68 | 0 | 1 | 0 | 6 | 2 | 0 | 0 | 12.1 | 23 | 17 | 16 | 5 | 11 | 2 | 0 |
| Carl Pavano |   | sp | 32 | 5.77 | 4 | 2 | 0 | 7 | 7 | 0 | 0 | 34.1 | 41 | 23 | 22 | 10 | 15 | 5 | 2 |
| Jake Peavy | MUL | sp | 27 | 2.85 | 10 | 11 | 0 | 27 | 27 | 1 | 0 | 173.2 | 146 | 57 | 55 | 59 | 166 | 17 | 12 |
| Jailen Peguero |   | mr | 27 | 4.82 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 9.1 | 9 | 6 | 5 | 4 | 5 | 0 | 3 |
| Mike Pelfrey |   | sp | 24 | 3.72 | 13 | 11 | 0 | 32 | 32 | 2 | 0 | 200.2 | 209 | 86 | 83 | 64 | 110 | 12 | 29 |
| Tony Pena |   | mr | 26 | 4.33 | 3 | 2 | 3 | 72 | 0 | 0 | 0 | 72.2 | 80 | 38 | 35 | 17 | 52 | 5 | 6 |
| Brad Penny |   | sp | 30 | 6.27 | 6 | 9 | 0 | 19 | 17 | 0 | 0 | 94.2 | 112 | 68 | 66 | 42 | 51 | 13 | 12 |
| Joel Peralta | MID | mr | 32 | 5.98 | 1 | 2 | 0 | 40 | 0 | 0 | 0 | 52.2 | 56 | 37 | 35 | 14 | 38 | 15 | 5 |
| Troy Percival |   | cl | 38 | 4.53 | 2 | 1 | 28 | 50 | 0 | 0 | 0 | 45.2 | 29 | 26 | 23 | 27 | 38 | 9 | 0 |
| Chris Perez | LON | mr | 22 | 3.46 | 3 | 3 | 7 | 41 | 0 | 0 | 0 | 41.2 | 34 | 18 | 16 | 22 | 42 | 5 | 7 |
| Odalis Perez* |   | sp | 31 | 4.34 | 7 | 12 | 0 | 30 | 30 | 0 | 0 | 159.2 | 182 | 87 | 77 | 55 | 119 | 22 | 12 |
| Oliver Perez* | WIZ | sp | 26 | 4.22 | 10 | 7 | 0 | 34 | 34 | 0 | 0 | 194.0 | 167 | 100 | 91 | 105 | 180 | 24 | 15 |
| Rafael Perez* | BT | mr | 26 | 3.54 | 4 | 4 | 2 | 73 | 0 | 0 | 0 | 76.1 | 67 | 32 | 30 | 23 | 86 | 8 | 10 |
| Glen Perkins* | BON | sp | 25 | 4.41 | 12 | 4 | 0 | 26 | 26 | 0 | 0 | 151.0 | 183 | 81 | 74 | 39 | 74 | 25 | 12 |
| Yusmeiro Petit | WIZ | mr | 23 | 4.31 | 3 | 5 | 0 | 19 | 8 | 0 | 0 | 56.1 | 45 | 29 | 27 | 14 | 42 | 12 | 1 |
| Andy Pettitte* |   | sp | 36 | 4.54 | 14 | 14 | 0 | 33 | 33 | 0 | 0 | 204.0 | 233 | 112 | 103 | 55 | 158 | 19 | 15 |
| Adam Pettyjohn* |   | mr | 31 | 20.25 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 4.0 | 11 | 9 | 9 | 2 | 1 | 2 | 0 |
| Carmen Pignatiello* |   | mr | 25 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.2 | 2 | 1 | 1 | 2 | 0 | 0 | 0 |
| Joel Pineiro | CCL | sp | 29 | 5.15 | 7 | 7 | 1 | 26 | 25 | 0 | 0 | 148.2 | 180 | 89 | 85 | 35 | 81 | 22 | 14 |
| Renyel Pinto* |   | mr | 25 | 4.45 | 2 | 5 | 0 | 67 | 0 | 0 | 0 | 64.2 | 52 | 33 | 32 | 39 | 56 | 9 | 7 |
| Sidney Ponson |   | sp | 31 | 5.04 | 8 | 5 | 0 | 25 | 24 | 1 | 0 | 135.2 | 170 | 89 | 76 | 48 | 58 | 14 | 17 |
| David Price* |   | mr | 22 | 1.93 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 14.0 | 9 | 4 | 3 | 4 | 12 | 1 | 1 |
| Scott Proctor |   | mr | 31 | 6.05 | 2 | 0 | 0 | 41 | 0 | 0 | 0 | 38.2 | 41 | 30 | 26 | 24 | 46 | 7 | 0 |
| David Purcey* |   | sp | 26 | 5.54 | 3 | 6 | 0 | 12 | 12 | 1 | 0 | 65.0 | 67 | 41 | 40 | 29 | 58 | 9 | 4 |
| J.J. Putz | MID | cl | 31 | 3.88 | 6 | 5 | 15 | 47 | 0 | 0 | 0 | 46.1 | 46 | 20 | 20 | 28 | 56 | 4 | 3 |
| Chad Qualls | BON | mr | 29 | 2.81 | 4 | 8 | 9 | 77 | 0 | 0 | 0 | 73.2 | 61 | 29 | 23 | 18 | 71 | 4 | 13 |
| Edwar Ramirez | EDG | mr | 27 | 3.90 | 5 | 1 | 1 | 55 | 0 | 0 | 0 | 55.1 | 44 | 25 | 24 | 24 | 63 | 7 | 1 |
| Elizardo Ramirez |   | mr | 25 | 30.38 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 2.2 | 8 | 9 | 9 | 2 | 1 | 1 | 0 |
| Horacio Ramirez* |   | mr | 28 | 4.34 | 1 | 4 | 0 | 32 | 0 | 0 | 0 | 37.1 | 45 | 20 | 18 | 9 | 13 | 1 | 1 |
| Ramon Ramirez | LON | mr | 26 | 2.64 | 3 | 2 | 1 | 71 | 0 | 0 | 0 | 71.2 | 57 | 23 | 21 | 31 | 70 | 2 | 7 |
| Ramon Ramirez |   | sp | 25 | 2.67 | 1 | 1 | 0 | 5 | 4 | 0 | 0 | 27.0 | 17 | 8 | 8 | 11 | 21 | 3 | 3 |
| Clay Rapada* |   | mr | 27 | 4.22 | 3 | 0 | 0 | 25 | 0 | 0 | 0 | 21.1 | 19 | 11 | 10 | 14 | 15 | 0 | 2 |
| Darrell Rasner |   | sp | 27 | 5.40 | 5 | 10 | 0 | 24 | 20 | 0 | 0 | 113.1 | 135 | 74 | 68 | 39 | 67 | 14 | 11 |
| Jon Rauch |   | mr | 29 | 4.14 | 4 | 8 | 18 | 74 | 0 | 0 | 0 | 71.2 | 69 | 36 | 33 | 16 | 66 | 11 | 3 |
| Tim Redding |   | sp | 30 | 4.95 | 10 | 11 | 0 | 33 | 33 | 1 | 0 | 182.0 | 195 | 110 | 100 | 65 | 120 | 27 | 15 |
| Mark Redman* |   | sp | 34 | 7.54 | 2 | 5 | 0 | 10 | 9 | 0 | 0 | 45.1 | 61 | 40 | 38 | 16 | 20 | 7 | 6 |
| Steven Register |   | mr | 25 | 9.00 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 10.0 | 13 | 10 | 10 | 6 | 8 | 4 | 0 |
| Chad Reineke |   | sp | 26 | 5.00 | 2 | 1 | 0 | 4 | 3 | 0 | 0 | 18.0 | 14 | 10 | 10 | 12 | 13 | 1 | 1 |
| Chris Resop |   | mr | 25 | 5.89 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 18.1 | 16 | 12 | 12 | 10 | 13 | 2 | 1 |
| Al Reyes |   | mr | 38 | 4.37 | 2 | 2 | 0 | 26 | 0 | 0 | 0 | 22.2 | 21 | 12 | 11 | 10 | 19 | 2 | 2 |
| Anthony Reyes |   | sp | 26 | 2.76 | 4 | 2 | 1 | 16 | 6 | 0 | 0 | 49.0 | 47 | 15 | 15 | 15 | 25 | 4 | 5 |
| Dennys Reyes* |   | mr | 31 | 2.33 | 3 | 0 | 0 | 75 | 0 | 0 | 0 | 46.1 | 40 | 12 | 12 | 15 | 39 | 4 | 8 |
| Jo-Jo Reyes* |   | sp | 23 | 5.81 | 3 | 11 | 0 | 23 | 22 | 0 | 0 | 113.0 | 134 | 77 | 73 | 52 | 78 | 18 | 15 |
| Greg Reynolds |   | sp | 22 | 8.13 | 2 | 8 | 0 | 14 | 13 | 0 | 0 | 62.0 | 83 | 58 | 56 | 26 | 22 | 14 | 5 |
| Arthur Rhodes* | OTR | mr | 38 | 2.04 | 4 | 1 | 2 | 61 | 0 | 0 | 0 | 35.1 | 28 | 9 | 8 | 16 | 40 | 0 | 3 |
| Clayton Richard* |   | sp | 24 | 6.04 | 2 | 5 | 0 | 13 | 8 | 0 | 0 | 47.2 | 61 | 37 | 32 | 13 | 29 | 5 | 4 |
| Scott Richmond |   | sp | 28 | 4.00 | 1 | 3 | 0 | 5 | 5 | 1 | 1 | 27.0 | 32 | 12 | 12 | 2 | 20 | 2 | 3 |
| Jeff Ridgway* |   | mr | 27 | 3.72 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 9.2 | 7 | 4 | 4 | 1 | 8 | 3 | 0 |
| Juan Rincon |   | mr | 29 | 5.86 | 3 | 3 | 0 | 47 | 0 | 0 | 0 | 55.1 | 67 | 39 | 36 | 24 | 39 | 8 | 6 |
| Ricardo Rincon* |   | mr | 38 | 4.50 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 4.0 | 4 | 2 | 2 | 1 | 3 | 1 | 0 |
| Royce Ring* |   | mr | 27 | 8.46 | 2 | 1 | 0 | 42 | 0 | 0 | 0 | 22.1 | 32 | 25 | 21 | 10 | 16 | 2 | 3 |
| David Riske |   | mr | 31 | 5.31 | 1 | 2 | 2 | 45 | 0 | 0 | 0 | 42.1 | 47 | 25 | 25 | 25 | 27 | 6 | 3 |
| Mariano Rivera | ROK | cl | 38 | 1.40 | 6 | 5 | 39 | 64 | 0 | 0 | 0 | 70.2 | 41 | 11 | 11 | 6 | 77 | 4 | 2 |
| Saul Rivera |   | mr | 30 | 3.96 | 5 | 6 | 0 | 76 | 0 | 0 | 0 | 84.0 | 90 | 41 | 37 | 35 | 65 | 3 | 9 |
| Connor Robertson |   | mr | 26 | 5.14 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 7.0 | 8 | 4 | 4 | 2 | 2 | 1 | 0 |
| David Robertson |   | mr | 23 | 5.34 | 4 | 0 | 0 | 25 | 0 | 0 | 0 | 30.1 | 29 | 18 | 18 | 15 | 36 | 3 | 1 |
| Nate Robertson* |   | sp | 30 | 6.35 | 7 | 11 | 0 | 32 | 28 | 0 | 0 | 168.2 | 218 | 124 | 119 | 62 | 108 | 26 | 23 |
| Fernando Rodney | OTR | cl | 31 | 4.91 | 0 | 6 | 13 | 38 | 0 | 0 | 0 | 40.1 | 34 | 22 | 22 | 30 | 49 | 3 | 1 |
| Francisco Rodriguez | BON | cl | 26 | 2.24 | 2 | 3 | 62 | 76 | 0 | 0 | 0 | 68.1 | 54 | 21 | 17 | 34 | 77 | 4 | 5 |
| Wandy Rodriguez* | BT | sp | 29 | 3.54 | 9 | 7 | 0 | 25 | 25 | 0 | 0 | 137.1 | 136 | 65 | 54 | 44 | 131 | 14 | 11 |
| Josh Roenicke |   | mr | 25 | 9.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3.0 | 6 | 3 | 3 | 2 | 6 | 0 | 0 |
| Kenny Rogers* |   | sp | 43 | 5.70 | 9 | 13 | 0 | 30 | 30 | 0 | 0 | 173.2 | 212 | 118 | 110 | 71 | 82 | 22 | 25 |
| J.C. Romero* |   | mr | 32 | 2.75 | 4 | 4 | 1 | 81 | 0 | 0 | 0 | 59.0 | 41 | 18 | 18 | 38 | 52 | 5 | 3 |
| Sergio Romo |   | mr | 25 | 2.12 | 3 | 1 | 0 | 29 | 0 | 0 | 0 | 34.0 | 16 | 13 | 8 | 8 | 33 | 3 | 0 |
| Carlos Rosa |   | mr | 23 | 2.70 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.1 | 3 | 1 | 1 | 0 | 3 | 0 | 0 |
| Leo Rosales |   | mr | 27 | 4.20 | 1 | 1 | 0 | 27 | 0 | 0 | 0 | 30.0 | 32 | 15 | 14 | 15 | 18 | 2 | 2 |
| Ryan Rowland-Smith* | CRH | mr | 25 | 3.42 | 5 | 3 | 2 | 47 | 12 | 0 | 0 | 118.1 | 114 | 49 | 45 | 48 | 77 | 13 | 11 |
| Rich Rundles* |   | mr | 27 | 1.80 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 5.0 | 5 | 1 | 1 | 3 | 6 | 0 | 1 |
| Josh Rupe |   | mr | 25 | 5.14 | 3 | 1 | 0 | 46 | 0 | 0 | 0 | 89.1 | 93 | 52 | 51 | 46 | 53 | 8 | 20 |
| Glendon Rusch* |   | mr | 33 | 5.16 | 5 | 5 | 0 | 35 | 9 | 0 | 0 | 83.2 | 94 | 50 | 48 | 25 | 55 | 10 | 3 |
| Adam Russell |   | mr | 25 | 5.19 | 4 | 0 | 0 | 22 | 0 | 0 | 0 | 26.0 | 30 | 15 | 15 | 10 | 22 | 1 | 2 |
| B.J. Ryan* | CRH | cl | 32 | 2.95 | 2 | 4 | 32 | 60 | 0 | 0 | 0 | 58.0 | 46 | 21 | 19 | 28 | 58 | 4 | 5 |
| Jae Kuk Ryu |   | mr | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| Kirk Saarloos |   | mr | 29 | 5.47 | 1 | 0 | 0 | 8 | 1 | 0 | 0 | 26.1 | 37 | 17 | 16 | 4 | 12 | 2 | 3 |
| C.C. Sabathia* | CRH | sp | 27 | 2.70 | 17 | 10 | 0 | 35 | 35 | 10 | 5 | 253.0 | 223 | 85 | 76 | 59 | 251 | 19 | 20 |
| Billy Sadler |   | mr | 26 | 4.06 | 0 | 1 | 0 | 33 | 0 | 0 | 0 | 44.1 | 34 | 21 | 20 | 27 | 42 | 6 | 3 |
| Takashi Saito | Pal | cl | 38 | 2.49 | 4 | 4 | 18 | 45 | 0 | 0 | 0 | 47.0 | 40 | 14 | 13 | 16 | 60 | 1 | 2 |
| Juan Salas |   | mr | 29 | 7.11 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.1 | 5 | 5 | 5 | 4 | 8 | 0 | 0 |
| Marino Salas |   | mr | 26 | 8.47 | 1 | 0 | 0 | 13 | 0 | 0 | 0 | 17.0 | 25 | 16 | 16 | 14 | 9 | 4 | 3 |
| Jeff Samardzija |   | mr | 23 | 2.28 | 1 | 0 | 1 | 26 | 0 | 0 | 0 | 27.2 | 24 | 12 | 7 | 15 | 25 | 0 | 0 |
| Chris Sampson | MUL | mr | 30 | 4.22 | 6 | 4 | 0 | 54 | 11 | 0 | 0 | 117.1 | 118 | 60 | 55 | 23 | 61 | 8 | 17 |
| Brian Sanches |   | mr | 29 | 7.36 | 2 | 0 | 0 | 12 | 0 | 0 | 0 | 11.0 | 16 | 10 | 9 | 5 | 10 | 2 | 2 |
| Anibal Sanchez | MAD | sp | 24 | 5.57 | 2 | 5 | 0 | 10 | 10 | 0 | 0 | 51.2 | 54 | 35 | 32 | 27 | 50 | 7 | 1 |
| Duaner Sanchez | BT | mr | 28 | 4.32 | 5 | 1 | 0 | 66 | 0 | 0 | 0 | 58.1 | 54 | 28 | 28 | 23 | 44 | 6 | 3 |
| Humberto Sanchez |   | mr | 25 | 4.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 1 | 1 | 1 | 2 | 1 | 0 | 1 |
| Jonathan Sanchez* | MAD | sp | 25 | 5.01 | 9 | 12 | 0 | 29 | 29 | 0 | 0 | 158.0 | 154 | 90 | 88 | 75 | 157 | 14 | 13 |
| Romulo Sanchez |   | mr | 24 | 4.05 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 13.1 | 14 | 6 | 6 | 6 | 3 | 0 | 4 |
| Ervin Santana | BON | sp | 25 | 3.49 | 16 | 7 | 0 | 32 | 32 | 2 | 1 | 219.0 | 198 | 89 | 85 | 47 | 214 | 23 | 10 |
| Johan Santana* | ROK | sp | 29 | 2.53 | 16 | 7 | 0 | 34 | 34 | 3 | 2 | 234.1 | 206 | 74 | 66 | 63 | 206 | 23 | 12 |
| Dennis Sarfate |   | mr | 27 | 4.74 | 4 | 3 | 0 | 57 | 4 | 0 | 0 | 79.2 | 62 | 47 | 42 | 62 | 86 | 8 | 11 |
| Joe Saunders* | MID | sp | 27 | 3.41 | 17 | 7 | 0 | 31 | 31 | 1 | 0 | 198.0 | 187 | 82 | 75 | 53 | 103 | 21 | 28 |
| Max Scherzer | LON | mr | 23 | 3.05 | 0 | 4 | 0 | 16 | 7 | 0 | 0 | 56.0 | 48 | 24 | 19 | 21 | 66 | 5 | 5 |
| Scott Schoeneweis* |   | mr | 34 | 3.34 | 2 | 6 | 1 | 73 | 0 | 0 | 0 | 56.2 | 55 | 23 | 21 | 23 | 34 | 7 | 6 |
| Chris Schroder |   | mr | 29 | 5.40 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.0 | 6 | 3 | 3 | 6 | 3 | 2 | 0 |
| Rudy Seanez | TON | mr | 39 | 3.53 | 5 | 4 | 0 | 42 | 0 | 0 | 0 | 43.1 | 38 | 24 | 17 | 25 | 30 | 2 | 4 |
| Bobby Seay* |   | mr | 30 | 4.47 | 1 | 2 | 0 | 60 | 0 | 0 | 0 | 56.1 | 59 | 28 | 28 | 25 | 58 | 4 | 3 |
| Alex Serrano |   | mr | 27 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Ben Sheets | CRH | sp | 29 | 3.09 | 13 | 9 | 0 | 31 | 31 | 5 | 3 | 198.1 | 181 | 74 | 68 | 47 | 158 | 17 | 8 |
| Steven Shell | CRH | mr | 25 | 2.16 | 2 | 2 | 2 | 39 | 0 | 0 | 0 | 50.0 | 34 | 14 | 12 | 20 | 41 | 5 | 4 |
| George Sherrill* | ROK | cl | 31 | 4.72 | 3 | 5 | 31 | 57 | 0 | 0 | 0 | 53.1 | 47 | 28 | 28 | 33 | 58 | 6 | 4 |
| James Shields | BON | sp | 26 | 3.56 | 14 | 8 | 0 | 33 | 33 | 3 | 2 | 215.0 | 208 | 94 | 85 | 40 | 160 | 24 | 21 |
| Scot Shields | ROK | mr | 32 | 2.70 | 6 | 4 | 4 | 64 | 0 | 0 | 0 | 63.1 | 56 | 29 | 19 | 29 | 64 | 6 | 11 |
| Brian Shouse* | OTR | mr | 39 | 2.81 | 5 | 1 | 2 | 69 | 0 | 0 | 0 | 51.1 | 46 | 19 | 16 | 14 | 33 | 5 | 5 |
| Carlos Silva |   | sp | 29 | 6.46 | 4 | 15 | 0 | 28 | 28 | 1 | 0 | 153.1 | 213 | 114 | 110 | 32 | 69 | 20 | 18 |
| Alfredo Simon |   | mr | 27 | 6.23 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 13.0 | 16 | 10 | 9 | 2 | 8 | 4 | 1 |
| Doug Slaten* |   | mr | 28 | 4.73 | 0 | 3 | 0 | 45 | 0 | 0 | 0 | 32.1 | 33 | 20 | 17 | 14 | 20 | 4 | 4 |
| Brian Slocum |   | mr | 27 | 27.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 8 | 6 | 6 | 0 | 1 | 2 | 0 |
| Kevin Slowey |   | sp | 24 | 3.99 | 12 | 11 | 0 | 27 | 27 | 3 | 2 | 160.1 | 161 | 74 | 71 | 24 | 123 | 22 | 10 |
| Chris Smith |   | mr | 27 | 7.85 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 18.1 | 18 | 16 | 16 | 7 | 13 | 6 | 1 |
| Greg Smith* |   | sp | 24 | 4.16 | 7 | 16 | 0 | 32 | 32 | 2 | 0 | 190.1 | 169 | 92 | 88 | 87 | 111 | 21 | 13 |
| Joe Smith | MAD | mr | 24 | 3.55 | 6 | 3 | 0 | 82 | 0 | 0 | 0 | 63.1 | 51 | 28 | 25 | 31 | 52 | 4 | 5 |
| John Smoltz |   | sp | 41 | 2.57 | 3 | 2 | 0 | 6 | 5 | 0 | 0 | 28.0 | 25 | 8 | 8 | 8 | 36 | 2 | 0 |
| Ian Snell |   | sp | 26 | 5.42 | 7 | 12 | 0 | 31 | 31 | 0 | 0 | 164.1 | 201 | 107 | 99 | 89 | 135 | 18 | 17 |
| Kyle Snyder |   | mr | 30 | 21.60 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.2 | 2 | 4 | 4 | 2 | 1 | 1 | 0 |
| Andy Sonnanstine | EDG | sp | 25 | 4.38 | 13 | 9 | 0 | 32 | 32 | 1 | 1 | 193.1 | 212 | 105 | 94 | 37 | 124 | 21 | 16 |
| Joakim Soria | BON | cl | 24 | 1.60 | 2 | 3 | 42 | 63 | 0 | 0 | 0 | 67.1 | 39 | 13 | 12 | 19 | 66 | 5 | 5 |
| Rafael Soriano | GEO | mr | 28 | 2.57 | 0 | 1 | 3 | 14 | 0 | 0 | 0 | 14.0 | 7 | 5 | 4 | 9 | 16 | 1 | 1 |
| Jorge Sosa |   | mr | 31 | 7.06 | 4 | 1 | 0 | 20 | 0 | 0 | 0 | 21.2 | 30 | 23 | 17 | 11 | 12 | 4 | 1 |
| Jeremy Sowers* |   | sp | 25 | 5.58 | 4 | 9 | 0 | 22 | 22 | 0 | 0 | 121.0 | 141 | 84 | 75 | 39 | 64 | 18 | 12 |
| Justin Speier |   | mr | 34 | 5.03 | 2 | 8 | 0 | 62 | 0 | 0 | 0 | 68.0 | 69 | 41 | 38 | 27 | 56 | 15 | 4 |
| Ryan Speier | MUL | mr | 28 | 4.06 | 2 | 1 | 0 | 43 | 0 | 0 | 0 | 51.0 | 52 | 23 | 23 | 18 | 33 | 3 | 9 |
| Levale Speigner |   | mr | 27 | 11.25 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 8.0 | 13 | 10 | 10 | 6 | 1 | 1 | 2 |
| Russ Springer | WIZ | mr | 39 | 2.32 | 2 | 1 | 0 | 70 | 0 | 0 | 0 | 50.1 | 39 | 14 | 13 | 18 | 45 | 4 | 2 |
| Mitch Stetter* |   | mr | 27 | 3.20 | 3 | 1 | 0 | 30 | 0 | 0 | 0 | 25.1 | 14 | 9 | 9 | 19 | 31 | 2 | 2 |
| Phil Stockman |   | mr | 28 | 0.00 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.1 | 2 | 0 | 0 | 4 | 9 | 0 | 1 |
| Brian Stokes |   | mr | 28 | 3.51 | 1 | 0 | 1 | 24 | 1 | 0 | 0 | 33.1 | 35 | 13 | 13 | 8 | 26 | 5 | 4 |
| Huston Street | GEO | cl | 24 | 3.73 | 7 | 5 | 18 | 63 | 0 | 0 | 0 | 70.0 | 58 | 29 | 29 | 27 | 69 | 6 | 6 |
| Eric Stults* |   | sp | 28 | 3.49 | 2 | 3 | 0 | 7 | 7 | 1 | 1 | 38.2 | 38 | 18 | 15 | 13 | 30 | 6 | 1 |
| Tanyon Sturtze |   | mr | 37 | 0.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
| Jeff Suppan |   | sp | 33 | 4.96 | 10 | 10 | 0 | 31 | 31 | 0 | 0 | 177.2 | 207 | 110 | 98 | 67 | 90 | 30 | 22 |
| R.J. Swindle* |   | mr | 24 | 7.71 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.2 | 9 | 4 | 4 | 2 | 4 | 2 | 0 |
| Mitch Talbot |   | mr | 24 | 11.17 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 9.2 | 16 | 12 | 12 | 11 | 5 | 3 | 2 |
| Brian Tallet* | EDG | mr | 30 | 2.88 | 1 | 2 | 0 | 51 | 0 | 0 | 0 | 56.1 | 52 | 19 | 18 | 22 | 47 | 4 | 3 |
| Taylor Tankersley* |   | mr | 25 | 8.15 | 0 | 1 | 0 | 25 | 0 | 0 | 0 | 17.2 | 22 | 16 | 16 | 8 | 13 | 6 | 1 |
| Jack Taschner* |   | mr | 30 | 4.88 | 3 | 2 | 0 | 67 | 0 | 0 | 0 | 48.0 | 57 | 27 | 26 | 24 | 39 | 5 | 3 |
| Ty Taubenheim |   | sp | 25 | 3.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6.0 | 7 | 2 | 2 | 3 | 4 | 0 | 0 |
| Julian Tavarez |   | mr | 35 | 5.10 | 1 | 5 | 0 | 52 | 0 | 0 | 0 | 54.2 | 73 | 42 | 31 | 28 | 51 | 5 | 4 |
| Robinson Tejeda | OTR | mr | 26 | 3.97 | 2 | 2 | 0 | 29 | 1 | 0 | 0 | 45.1 | 27 | 23 | 20 | 24 | 45 | 4 | 2 |
| Joe Thatcher* |   | mr | 26 | 8.42 | 0 | 4 | 0 | 25 | 0 | 0 | 0 | 25.2 | 42 | 25 | 24 | 13 | 17 | 4 | 3 |
| Justin Thomas* |   | mr | 24 | 6.75 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 4.0 | 9 | 3 | 3 | 2 | 2 | 0 | 0 |
| Brad Thompson |   | mr | 26 | 5.15 | 6 | 3 | 0 | 26 | 6 | 0 | 0 | 64.2 | 72 | 38 | 37 | 19 | 32 | 5 | 10 |
| Daryl Thompson |   | sp | 22 | 6.91 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 14.1 | 20 | 11 | 11 | 7 | 6 | 3 | 2 |
| Rich Thompson |   | mr | 23 | 22.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 4 | 5 | 5 | 2 | 1 | 0 | 0 |
| Matt Thornton* | CRH | mr | 31 | 2.67 | 5 | 3 | 1 | 74 | 0 | 0 | 0 | 67.1 | 48 | 20 | 20 | 19 | 77 | 5 | 5 |
| Erick Threets* |   | mr | 26 | 3.60 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 10.0 | 11 | 4 | 4 | 9 | 6 | 1 | 2 |
| Mike Timlin |   | mr | 42 | 5.66 | 4 | 4 | 1 | 47 | 0 | 0 | 0 | 49.1 | 60 | 32 | 31 | 20 | 32 | 9 | 3 |
| Brett Tomko |   | sp | 35 | 6.30 | 2 | 7 | 0 | 22 | 10 | 0 | 0 | 70.0 | 83 | 51 | 49 | 18 | 49 | 11 | 5 |
| Salomon Torres | MUL | cl | 36 | 3.49 | 7 | 5 | 28 | 71 | 0 | 0 | 0 | 80.0 | 75 | 35 | 31 | 33 | 51 | 6 | 13 |
| Billy Traber* |   | mr | 28 | 7.02 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 16.2 | 23 | 13 | 13 | 7 | 11 | 3 | 1 |
| Steve Trachsel |   | sp | 37 | 8.39 | 2 | 5 | 0 | 10 | 8 | 0 | 0 | 39.2 | 53 | 41 | 37 | 27 | 16 | 10 | 4 |
| Ramon Troncoso |   | mr | 25 | 4.26 | 1 | 1 | 0 | 32 | 0 | 0 | 0 | 38.0 | 37 | 19 | 18 | 12 | 38 | 2 | 7 |
| Ryan Tucker |   | mr | 21 | 8.27 | 2 | 3 | 0 | 13 | 6 | 0 | 0 | 37.0 | 46 | 34 | 34 | 23 | 28 | 8 | 3 |
| Derrick Turnbow |   | mr | 30 | 15.63 | 0 | 1 | 1 | 8 | 0 | 0 | 0 | 6.1 | 12 | 11 | 11 | 13 | 5 | 1 | 1 |
| Merkin Valdez |   | mr | 26 | 1.69 | 1 | 0 | 0 | 17 | 1 | 0 | 0 | 16.0 | 14 | 5 | 3 | 7 | 13 | 1 | 1 |
| Jose Valverde | WIZ | cl | 28 | 3.38 | 6 | 3 | 44 | 74 | 0 | 0 | 0 | 72.0 | 62 | 28 | 27 | 23 | 83 | 10 | 0 |
| John Van Benschoten |   | sp | 28 | 10.48 | 1 | 3 | 0 | 9 | 5 | 0 | 0 | 22.1 | 37 | 28 | 26 | 20 | 21 | 7 | 3 |
| Rick VandenHurk |   | sp | 23 | 7.71 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 14.0 | 20 | 12 | 12 | 10 | 20 | 1 | 0 |
| Claudio Vargas |   | mr | 30 | 4.62 | 3 | 2 | 0 | 11 | 4 | 0 | 0 | 37.0 | 33 | 20 | 19 | 11 | 20 | 4 | 5 |
| Javier Vazquez | Pal | sp | 31 | 4.67 | 12 | 16 | 0 | 33 | 33 | 1 | 0 | 208.1 | 214 | 113 | 108 | 61 | 200 | 25 | 15 |
| Jose Veras |   | mr | 27 | 3.59 | 5 | 3 | 0 | 60 | 0 | 0 | 0 | 57.2 | 52 | 23 | 23 | 29 | 63 | 7 | 1 |
| Justin Verlander | COP | sp | 25 | 4.84 | 11 | 17 | 0 | 33 | 33 | 1 | 0 | 201.0 | 195 | 119 | 108 | 87 | 163 | 18 | 14 |
| Carlos Villanueva |   | mr | 24 | 4.07 | 4 | 7 | 1 | 47 | 9 | 0 | 0 | 108.1 | 112 | 53 | 49 | 30 | 93 | 18 | 6 |
| Oscar Villarreal |   | mr | 26 | 5.02 | 1 | 3 | 0 | 35 | 0 | 0 | 0 | 37.2 | 42 | 25 | 21 | 17 | 21 | 12 | 5 |
| Ron Villone* |   | mr | 38 | 4.68 | 1 | 2 | 1 | 74 | 0 | 0 | 0 | 50.0 | 45 | 27 | 26 | 37 | 50 | 4 | 7 |
| Luis Vizcaino |   | mr | 33 | 5.28 | 1 | 2 | 0 | 43 | 0 | 0 | 0 | 46.0 | 48 | 28 | 27 | 19 | 49 | 10 | 4 |
| Edinson Volquez | LON | sp | 24 | 3.21 | 17 | 6 | 0 | 33 | 32 | 0 | 0 | 196.0 | 167 | 82 | 70 | 93 | 206 | 14 | 14 |
| Chris Volstad | MAD | sp | 21 | 2.88 | 6 | 4 | 0 | 15 | 14 | 0 | 0 | 84.1 | 76 | 30 | 27 | 36 | 52 | 3 | 6 |
| Cory Wade | Pal | mr | 25 | 2.27 | 2 | 1 | 0 | 55 | 0 | 0 | 0 | 71.1 | 51 | 22 | 18 | 15 | 51 | 7 | 9 |
| Doug Waechter |   | mr | 27 | 3.69 | 4 | 2 | 0 | 48 | 0 | 0 | 0 | 63.1 | 63 | 29 | 26 | 21 | 46 | 7 | 2 |
| Billy Wagner* | BT | cl | 36 | 2.30 | 0 | 1 | 27 | 45 | 0 | 0 | 0 | 47.0 | 32 | 17 | 12 | 10 | 52 | 4 | 1 |
| Adam Wainwright | MAD | sp | 26 | 3.20 | 11 | 3 | 0 | 20 | 20 | 1 | 0 | 132.0 | 122 | 51 | 47 | 34 | 91 | 12 | 10 |
| Tim Wakefield | OTR | sp | 41 | 4.13 | 10 | 11 | 0 | 30 | 30 | 1 | 0 | 181.0 | 154 | 89 | 83 | 60 | 117 | 25 | 9 |
| Jamie Walker* | OTR | mr | 36 | 6.87 | 1 | 3 | 0 | 59 | 0 | 0 | 0 | 38.0 | 53 | 31 | 29 | 11 | 24 | 12 | 2 |
| Tyler Walker |   | mr | 32 | 4.56 | 5 | 8 | 0 | 65 | 0 | 0 | 0 | 53.1 | 47 | 29 | 27 | 21 | 49 | 7 | 5 |
| Les Walrond* |   | mr | 31 | 6.10 | 1 | 1 | 0 | 6 | 0 | 0 | 0 | 10.1 | 13 | 7 | 7 | 9 | 12 | 0 | 1 |
| Chien-Ming Wang | MID | sp | 28 | 4.07 | 8 | 2 | 0 | 15 | 15 | 1 | 0 | 95.0 | 90 | 44 | 43 | 35 | 54 | 4 | 12 |
| Jarrod Washburn* |   | sp | 33 | 4.69 | 5 | 14 | 1 | 28 | 26 | 1 | 0 | 153.2 | 174 | 87 | 80 | 50 | 87 | 19 | 15 |
| Ehren Wassermann |   | mr | 27 | 7.78 | 1 | 2 | 0 | 24 | 0 | 0 | 0 | 19.2 | 27 | 19 | 17 | 14 | 9 | 0 | 0 |
| Chris Waters* |   | sp | 27 | 5.01 | 3 | 5 | 0 | 11 | 11 | 1 | 1 | 64.2 | 70 | 38 | 36 | 29 | 33 | 9 | 5 |
| David Weathers |   | mr | 38 | 3.25 | 4 | 6 | 0 | 72 | 0 | 0 | 0 | 69.1 | 76 | 27 | 25 | 30 | 46 | 6 | 12 |
| Jered Weaver | OTR | sp | 25 | 4.33 | 11 | 10 | 0 | 30 | 30 | 0 | 0 | 176.2 | 173 | 88 | 85 | 54 | 152 | 20 | 8 |
| Brandon Webb | TON | sp | 29 | 3.30 | 22 | 7 | 0 | 34 | 34 | 3 | 1 | 226.2 | 206 | 95 | 83 | 65 | 183 | 13 | 25 |
| Todd Wellemeyer | Pal | sp | 29 | 3.71 | 13 | 9 | 0 | 32 | 32 | 0 | 0 | 191.2 | 178 | 84 | 79 | 62 | 134 | 25 | 9 |
| Jared Wells |   | mr | 26 | 8.64 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 8.1 | 11 | 8 | 8 | 7 | 5 | 2 | 0 |
| Kip Wells |   | mr | 31 | 6.21 | 1 | 3 | 0 | 25 | 2 | 0 | 0 | 37.2 | 39 | 29 | 26 | 30 | 31 | 4 | 8 |
| Randy Wells |   | mr | 25 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.1 | 0 | 0 | 0 | 3 | 1 | 0 | 1 |
| Jake Westbrook |   | sp | 30 | 3.12 | 1 | 2 | 0 | 5 | 5 | 1 | 0 | 34.2 | 33 | 13 | 12 | 7 | 19 | 5 | 5 |
| Dan Wheeler | Pal | mr | 30 | 3.12 | 5 | 6 | 13 | 70 | 0 | 0 | 0 | 66.1 | 44 | 25 | 23 | 22 | 53 | 10 | 2 |
| Bill White* |   | mr | 29 | 20.25 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 4.0 | 7 | 9 | 9 | 11 | 1 | 1 | 0 |
| Dontrelle Willis* |   | sp | 26 | 9.38 | 0 | 2 | 0 | 8 | 7 | 0 | 0 | 24.0 | 18 | 25 | 25 | 35 | 18 | 4 | 4 |
| Brian Wilson | MUL | cl | 26 | 4.62 | 3 | 2 | 41 | 63 | 0 | 0 | 0 | 62.1 | 62 | 32 | 32 | 28 | 67 | 7 | 7 |
| C.J. Wilson* | ROK | cl | 27 | 6.02 | 2 | 2 | 24 | 50 | 0 | 0 | 0 | 46.1 | 49 | 35 | 31 | 27 | 41 | 8 | 6 |
| Matt Wise |   | mr | 32 | 6.43 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 7.0 | 10 | 5 | 5 | 3 | 6 | 2 | 0 |
| Randy Wolf* | CCL | sp | 31 | 4.30 | 12 | 12 | 0 | 33 | 33 | 1 | 1 | 190.1 | 191 | 100 | 91 | 71 | 162 | 21 | 17 |
| Brian Wolfe |   | mr | 27 | 2.45 | 0 | 2 | 0 | 20 | 0 | 0 | 0 | 22.0 | 18 | 6 | 6 | 6 | 14 | 2 | 4 |
| Kerry Wood | MUL | cl | 31 | 3.26 | 5 | 4 | 34 | 65 | 0 | 0 | 0 | 66.1 | 54 | 24 | 24 | 18 | 84 | 3 | 1 |
| Jake Woods* |   | mr | 26 | 6.16 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 19.0 | 22 | 13 | 13 | 11 | 9 | 5 | 3 |
| Mark Worrell |   | mr | 25 | 7.94 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 5.2 | 8 | 5 | 5 | 4 | 4 | 1 | 2 |
| Jamey Wright |   | mr | 33 | 5.12 | 8 | 7 | 0 | 75 | 0 | 0 | 0 | 84.1 | 93 | 57 | 48 | 35 | 60 | 5 | 13 |
| Wesley Wright* |   | mr | 23 | 5.01 | 4 | 3 | 1 | 71 | 0 | 0 | 0 | 55.2 | 45 | 34 | 31 | 34 | 57 | 8 | 4 |
| Michael Wuertz | ROK | mr | 29 | 3.63 | 1 | 1 | 0 | 45 | 0 | 0 | 0 | 44.2 | 44 | 23 | 18 | 20 | 30 | 4 | 5 |
| Keiichi Yabu |   | mr | 39 | 3.57 | 3 | 6 | 0 | 60 | 0 | 0 | 0 | 68.0 | 63 | 33 | 27 | 32 | 48 | 3 | 8 |
| Yasuhiko Yabuta |   | mr | 35 | 4.78 | 1 | 3 | 0 | 31 | 0 | 0 | 0 | 37.2 | 41 | 21 | 20 | 17 | 25 | 6 | 5 |
| Tyler Yates |   | mr | 30 | 4.66 | 6 | 3 | 1 | 72 | 0 | 0 | 0 | 73.1 | 72 | 39 | 38 | 41 | 63 | 6 | 5 |
| Chris Young | COP | sp | 29 | 3.96 | 7 | 6 | 0 | 18 | 18 | 1 | 0 | 102.1 | 84 | 46 | 45 | 48 | 93 | 13 | 4 |
| Carlos Zambrano | CCL | sp | 27 | 3.91 | 14 | 6 | 0 | 30 | 30 | 1 | 1 | 188.2 | 172 | 85 | 82 | 72 | 130 | 18 | 17 |
| Brad Ziegler | CRH | mr | 28 | 1.06 | 3 | 0 | 11 | 47 | 0 | 0 | 0 | 59.2 | 47 | 8 | 7 | 22 | 30 | 2 | 20 |
| Charlie Zink |   | sp | 28 | 16.62 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.1 | 11 | 8 | 8 | 1 | 1 | 0 | 0 |
| Barry Zito* |   | sp | 30 | 5.15 | 10 | 17 | 0 | 32 | 32 | 0 | 0 | 180.0 | 186 | 115 | 103 | 102 | 120 | 16 | 12 |
| Joel Zumaya |   | mr | 23 | 3.47 | 0 | 2 | 1 | 21 | 0 | 0 | 0 | 23.1 | 24 | 13 | 9 | 22 | 22 | 3 | 1 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | CI | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | EDG | mr | 26 | 2 | 0 | 2 | 5 | 3 | 0 | 3 | 2 | 0 | 9.1 | 6.5 | 16.5 | 9.1 | 0.7 | 1.4 | 1.73 |
| Jeremy Accardo |   | mr | 26 | 1 | 0 | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 10.9 | 2.9 | 14.6 | 3.6 | 0.7 | 1.3 | 1.54 |
| Alfredo Aceves |   | sp | 25 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.5 | 3.0 | 10.5 | 4.8 | 1.2 | 1.6 | 1.17 |
| Manny Acosta |   | mr | 27 | 7 | 0 | 5 | 1 | 5 | 0 | 4 | 1 | 0 | 8.2 | 4.4 | 12.7 | 5.3 | 1.2 | 1.2 | 1.40 |
| Mike Adams | MUL | mr | 29 | 5 | 1 | 2 | 0 | 0 | 0 | 2 | 3 | 0 | 6.8 | 2.6 | 9.4 | 10.2 | 1.0 | 3.9 | 1.04 |
| Nick Adenhart |   | sp | 21 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 13.5 | 9.8 | 23.3 | 3.0 | 0.0 | 0.3 | 2.58 |
| Jon Adkins |   | mr | 30 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.8 | 7.4 | 17.2 | 7.4 | 2.5 | 1.0 | 1.91 |
| Jeremy Affeldt* | CRH | mr | 29 | 7 | 1 | 0 | 3 | 6 | 0 | 7 | 0 | 0 | 9.0 | 2.9 | 12.2 | 9.2 | 1.0 | 3.2 | 1.31 |
| Jonathan Albaladejo |   | mr | 25 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.9 | 4.0 | 13.8 | 8.6 | 0.7 | 2.2 | 1.54 |
| Matt Albers |   | mr | 25 | 3 | 1 | 1 | 2 | 1 | 0 | 1 | 3 | 1 | 7.9 | 4.0 | 12.3 | 4.8 | 0.7 | 1.2 | 1.33 |
| Greg Aquino |   | mr | 30 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 0 | 16.4 | 8.7 | 27.0 | 8.7 | 1.0 | 1.0 | 2.79 |
| Alberto Arias |   | mr | 24 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 9.6 | 4.2 | 14.5 | 5.4 | 0.4 | 1.3 | 1.52 |
| Tony Armas |   | mr | 30 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 11.9 | 1.1 | 13.0 | 6.5 | 2.2 | 6.0 | 1.44 |
| Jose Arredondo | COP | mr | 24 | 3 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.2 | 3.2 | 9.6 | 8.1 | 0.4 | 2.5 | 1.05 |
| Bronson Arroyo | BT | sp | 31 | 5 | 2 | 2 | 6 | 6 | 0 | 13 | 6 | 0 | 9.9 | 3.1 | 13.2 | 7.3 | 1.3 | 2.4 | 1.43 |
| Jose Ascanio |   | mr | 23 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 12.7 | 6.4 | 20.6 | 4.8 | 1.6 | 0.8 | 2.12 |
| Luis Ayala |   | mr | 30 | 2 | 1 | 4 | 4 | 1 | 0 | 4 | 3 | 0 | 10.2 | 2.9 | 13.6 | 5.9 | 1.1 | 2.1 | 1.45 |
| Brandon Backe |   | sp | 30 | 4 | 6 | 2 | 4 | 2 | 0 | 4 | 2 | 0 | 10.9 | 4.2 | 15.3 | 6.9 | 1.9 | 1.6 | 1.67 |
| Burke Badenhop |   | sp | 25 | 4 | 3 | 1 | 3 | 2 | 0 | 2 | 2 | 0 | 10.5 | 4.0 | 15.0 | 6.7 | 1.3 | 1.7 | 1.61 |
| Cha Seung Baek |   | sp | 28 | 9 | 5 | 3 | 3 | 4 | 0 | 3 | 8 | 0 | 9.3 | 2.7 | 12.3 | 5.9 | 1.1 | 2.1 | 1.34 |
| Homer Bailey |   | sp | 22 | 8 | 1 | 1 | 0 | 4 | 1 | 5 | 2 | 0 | 14.6 | 4.2 | 18.8 | 4.5 | 2.0 | 1.1 | 2.09 |
| Scott Baker | BON | sp | 26 | 8 | 5 | 2 | 3 | 6 | 0 | 2 | 3 | 0 | 8.4 | 2.2 | 10.8 | 7.4 | 1.0 | 3.4 | 1.18 |
| John Bale* |   | mr | 34 | 3 | 1 | 0 | 0 | 1 | 0 | 3 | 2 | 0 | 9.8 | 2.0 | 11.8 | 4.7 | 0.3 | 2.3 | 1.31 |
| Collin Balester |   | sp | 22 | 3 | 3 | 1 | 6 | 4 | 0 | 2 | 3 | 0 | 10.3 | 3.1 | 14.2 | 5.6 | 1.3 | 1.8 | 1.50 |
| Grant Balfour | COP | mr | 30 | 2 | 1 | 1 | 0 | 2 | 0 | 1 | 3 | 0 | 4.3 | 3.7 | 8.0 | 12.7 | 0.5 | 3.4 | 0.89 |
| Josh Banks |   | sp | 25 | 17 | 3 | 5 | 3 | 0 | 0 | 8 | 4 | 0 | 9.9 | 3.4 | 13.6 | 4.5 | 1.3 | 1.3 | 1.48 |
| Brian Bannister |   | sp | 27 | 6 | 3 | 1 | 7 | 7 | 1 | 3 | 10 | 1 | 10.6 | 2.9 | 13.8 | 5.6 | 1.4 | 1.9 | 1.49 |
| Jimmy Barthmaier |   | sp | 24 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 13.9 | 7.0 | 20.9 | 5.2 | 2.6 | 0.8 | 2.32 |
| Brian Bass |   | mr | 26 | 1 | 2 | 4 | 5 | 6 | 0 | 1 | 1 | 0 | 9.9 | 3.1 | 13.5 | 4.5 | 1.2 | 1.5 | 1.44 |
| Miguel Batista |   | mr | 37 | 19 | 2 | 6 | 6 | 5 | 0 | 3 | 11 | 0 | 10.6 | 6.2 | 17.2 | 5.7 | 1.5 | 0.9 | 1.86 |
| Rick Bauer |   | mr | 31 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 4.5 | 19.5 | 6.0 | 1.5 | 1.3 | 2.17 |
| Denny Bautista |   | mr | 27 | 7 | 2 | 2 | 2 | 4 | 0 | 2 | 4 | 0 | 9.1 | 6.3 | 15.7 | 6.6 | 0.9 | 1.0 | 1.71 |
| Yorman Bazardo |   | mr | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 21.0 | 15.0 | 36.0 | 9.0 | 0.0 | 0.6 | 4.00 |
| T.J. Beam |   | mr | 27 | 3 | 1 | 4 | 2 | 0 | 0 | 4 | 2 | 0 | 8.5 | 3.9 | 12.8 | 4.7 | 1.2 | 1.2 | 1.38 |
| Josh Beckett | Pal | sp | 28 | 7 | 5 | 1 | 9 | 5 | 0 | 4 | 3 | 0 | 8.9 | 1.8 | 11.2 | 8.9 | 0.9 | 5.1 | 1.19 |
| Erik Bedard* | GEO | sp | 29 | 5 | 1 | 0 | 4 | 3 | 0 | 1 | 2 | 0 | 7.8 | 4.1 | 12.3 | 8.0 | 1.0 | 1.9 | 1.32 |
| Joe Beimel* |   | mr | 31 | 5 | 3 | 4 | 3 | 1 | 1 | 1 | 4 | 0 | 9.2 | 3.9 | 13.6 | 5.9 | 0.0 | 1.5 | 1.45 |
| Matt Belisle |   | sp | 28 | 3 | 1 | 0 | 0 | 2 | 0 | 1 | 2 | 0 | 14.3 | 1.8 | 16.1 | 4.2 | 1.2 | 2.3 | 1.79 |
| Heath Bell | MUL | mr | 30 | 10 | 2 | 4 | 3 | 2 | 0 | 3 | 2 | 0 | 7.6 | 3.2 | 11.2 | 8.2 | 0.6 | 2.5 | 1.21 |
| Francis Beltran |   | mr | 28 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 4.2 | 13.2 | 6.2 | 2.1 | 1.5 | 1.46 |
| Armando Benitez |   | mr | 35 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.7 | 2.8 | 8.5 | 12.8 | 4.3 | 4.5 | 0.95 |
| Jeff Bennett | TON | mr | 28 | 7 | 3 | 6 | 7 | 5 | 0 | 6 | 5 | 0 | 8.0 | 4.3 | 12.9 | 6.3 | 0.5 | 1.4 | 1.37 |
| Joaquin Benoit | OTR | mr | 30 | 1 | 1 | 2 | 0 | 3 | 0 | 2 | 0 | 0 | 8.0 | 7.0 | 15.0 | 8.6 | 1.2 | 1.2 | 1.67 |
| Jason Bergmann |   | sp | 26 | 9 | 1 | 2 | 1 | 2 | 0 | 9 | 8 | 0 | 9.9 | 3.0 | 13.0 | 6.2 | 1.6 | 2.0 | 1.43 |
| Rafael Betancourt | GEO | mr | 33 | 10 | 1 | 5 | 0 | 2 | 0 | 4 | 5 | 0 | 9.6 | 3.2 | 12.8 | 8.1 | 1.4 | 2.6 | 1.42 |
| Randor Bierd |   | mr | 24 | 0 | 0 | 2 | 3 | 4 | 0 | 1 | 3 | 0 | 11.8 | 4.7 | 17.2 | 6.1 | 0.7 | 1.3 | 1.83 |
| Chad Billingsley | TON | sp | 23 | 8 | 4 | 6 | 8 | 10 | 0 | 8 | 5 | 0 | 8.4 | 3.6 | 12.4 | 9.0 | 0.6 | 2.5 | 1.34 |
| Kurt Birkins* |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.5 | 4.5 | 9.0 | 6.3 | 0.0 | 1.4 | 1.00 |
| Nick Blackburn |   | sp | 26 | 2 | 2 | 4 | 7 | 2 | 0 | 5 | 4 | 0 | 10.4 | 1.8 | 12.6 | 4.5 | 1.1 | 2.5 | 1.36 |
| Joe Blanton |   | sp | 27 | 4 | 1 | 3 | 4 | 2 | 0 | 2 | 4 | 0 | 9.6 | 3.0 | 12.8 | 5.1 | 1.0 | 1.7 | 1.40 |
| Jerry Blevins* |   | mr | 24 | 2 | 2 | 2 | 3 | 0 | 0 | 0 | 1 | 0 | 7.6 | 3.1 | 11.5 | 8.4 | 0.5 | 2.7 | 1.19 |
| Mitchell Boggs |   | sp | 24 | 2 | 0 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 11.1 | 5.8 | 17.5 | 3.4 | 1.3 | 0.6 | 1.88 |
| Jeremy Bonderman |   | sp | 25 | 2 | 5 | 2 | 3 | 1 | 0 | 2 | 3 | 0 | 9.5 | 4.5 | 14.4 | 5.6 | 1.1 | 1.2 | 1.56 |
| Eddie Bonine |   | sp | 27 | 2 | 1 | 0 | 2 | 0 | 0 | 1 | 1 | 0 | 12.1 | 1.7 | 14.5 | 3.0 | 1.0 | 1.8 | 1.54 |
| Boof Bonser |   | mr | 26 | 11 | 0 | 1 | 1 | 6 | 1 | 3 | 4 | 0 | 10.6 | 2.7 | 13.4 | 7.4 | 1.2 | 2.7 | 1.48 |
| Chris Bootcheck |   | mr | 29 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 16.9 | 6.8 | 23.6 | 7.9 | 1.1 | 1.2 | 2.63 |
| Dave Borkowski |   | mr | 31 | 0 | 0 | 5 | 1 | 0 | 0 | 3 | 0 | 0 | 13.5 | 3.5 | 17.3 | 6.0 | 2.3 | 1.7 | 1.89 |
| Joe Borowski |   | cl | 37 | 6 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 13.0 | 4.3 | 17.3 | 4.9 | 2.2 | 1.1 | 1.92 |
| Michael Bowden |   | sp | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.6 | 1.8 | 14.4 | 5.4 | 0.0 | 3.0 | 1.60 |
| Cedrick Bowers* |   | mr | 30 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 14.8 | 6.8 | 22.9 | 6.8 | 2.7 | 1.0 | 2.40 |
| Micah Bowie* |   | mr | 33 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 12.4 | 3.4 | 16.9 | 5.6 | 1.1 | 1.7 | 1.75 |
| Blaine Boyer |   | mr | 26 | 8 | 2 | 4 | 2 | 2 | 0 | 3 | 4 | 0 | 9.1 | 3.1 | 12.5 | 8.4 | 1.3 | 2.7 | 1.36 |
| Dallas Braden* |   | sp | 24 | 1 | 2 | 2 | 2 | 0 | 1 | 1 | 2 | 0 | 9.7 | 3.1 | 13.1 | 5.1 | 1.0 | 1.6 | 1.42 |
| Chad Bradford | MID | mr | 33 | 3 | 4 | 6 | 2 | 0 | 0 | 3 | 5 | 0 | 8.9 | 2.3 | 11.5 | 2.6 | 0.5 | 1.1 | 1.25 |
| Bill Bray* |   | mr | 25 | 4 | 0 | 5 | 1 | 2 | 0 | 3 | 1 | 0 | 9.6 | 4.6 | 14.4 | 10.3 | 0.8 | 2.3 | 1.57 |
| Yhency Brazoban |   | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 12.0 | 9.0 | 21.0 | 9.0 | 0.0 | 1.0 | 2.33 |
| Craig Breslow* | MID | mr | 27 | 2 | 5 | 2 | 0 | 4 | 1 | 2 | 0 | 0 | 6.5 | 3.6 | 10.1 | 7.5 | 0.2 | 2.1 | 1.13 |
| Chris Britton |   | mr | 25 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 11.0 | 4.3 | 15.3 | 4.7 | 1.6 | 1.1 | 1.70 |
| Lance Broadway |   | mr | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.9 | 3.2 | 16.1 | 4.5 | 2.6 | 1.4 | 1.79 |
| Doug Brocail |   | mr | 41 | 3 | 1 | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 8.3 | 2.8 | 11.4 | 8.4 | 1.0 | 3.0 | 1.22 |
| Andrew Brown |   | mr | 27 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 5.9 | 5.4 | 11.6 | 7.2 | 0.8 | 1.3 | 1.26 |
| Jonathan Broxton | CCL | mr | 24 | 10 | 3 | 5 | 3 | 3 | 0 | 3 | 3 | 0 | 7.0 | 3.5 | 11.0 | 11.5 | 0.3 | 3.3 | 1.17 |
| Brian Bruney |   | mr | 26 | 3 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.7 | 4.2 | 9.2 | 8.7 | 0.5 | 2.1 | 0.99 |
| Clay Buchholz | COP | sp | 23 | 3 | 2 | 1 | 2 | 2 | 1 | 0 | 3 | 0 | 11.0 | 4.9 | 16.1 | 8.5 | 1.3 | 1.8 | 1.76 |
| Taylor Buchholz | TON | mr | 26 | 6 | 2 | 2 | 2 | 5 | 1 | 2 | 2 | 0 | 6.1 | 2.4 | 8.8 | 7.6 | 0.7 | 3.1 | 0.95 |
| Billy Buckner |   | mr | 24 | 0 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 10.3 | 2.6 | 13.5 | 7.1 | 1.9 | 2.8 | 1.43 |
| Mark Buehrle* | BON | sp | 29 | 5 | 7 | 4 | 5 | 4 | 0 | 2 | 6 | 0 | 9.9 | 2.1 | 12.2 | 5.8 | 0.9 | 2.7 | 1.34 |
| Francisley Bueno* |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.3 | 3.9 | 23.1 | 3.9 | 3.9 | 1.0 | 2.57 |
| Ryan Bukvich |   | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 15.2 | 10.1 | 25.3 | 8.4 | 3.4 | 0.8 | 2.81 |
| Jason Bulger |   | mr | 29 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 8.4 | 5.1 | 14.6 | 11.3 | 1.7 | 2.2 | 1.50 |
| Bryan Bullington |   | sp | 27 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 9.2 | 1.2 | 11.0 | 7.4 | 2.5 | 6.0 | 1.16 |
| A.J. Burnett | TON | sp | 31 | 22 | 9 | 2 | 9 | 11 | 2 | 8 | 5 | 0 | 8.6 | 3.5 | 12.4 | 9.4 | 0.8 | 2.7 | 1.34 |
| Sean Burnett* | WIZ | mr | 25 | 5 | 3 | 3 | 2 | 4 | 0 | 4 | 3 | 0 | 9.1 | 5.4 | 14.8 | 6.7 | 1.1 | 1.2 | 1.61 |
| Brian Burres* |   | sp | 27 | 11 | 2 | 2 | 6 | 3 | 1 | 1 | 8 | 0 | 11.5 | 3.5 | 15.3 | 4.4 | 1.2 | 1.3 | 1.66 |
| Jared Burton | MAD | mr | 27 | 4 | 1 | 3 | 2 | 2 | 1 | 2 | 3 | 0 | 8.6 | 3.8 | 12.7 | 8.9 | 0.9 | 2.3 | 1.38 |
| Dave Bush | OTR | sp | 28 | 17 | 9 | 3 | 10 | 2 | 1 | 4 | 3 | 0 | 7.9 | 2.3 | 10.8 | 5.3 | 1.4 | 2.3 | 1.14 |
| Paul Byrd |   | sp | 37 | 5 | 5 | 0 | 7 | 0 | 0 | 4 | 4 | 0 | 10.2 | 1.7 | 12.3 | 4.1 | 1.5 | 2.4 | 1.32 |
| Tim Byrdak* |   | mr | 34 | 4 | 1 | 2 | 2 | 0 | 0 | 2 | 1 | 0 | 7.3 | 4.7 | 12.4 | 7.6 | 1.6 | 1.6 | 1.34 |
| Daniel Cabrera |   | sp | 27 | 27 | 4 | 5 | 18 | 15 | 2 | 5 | 12 | 0 | 9.9 | 4.5 | 15.3 | 4.8 | 1.2 | 1.1 | 1.61 |
| Fernando Cabrera |   | mr | 26 | 4 | 2 | 2 | 0 | 3 | 0 | 0 | 2 | 0 | 10.2 | 5.4 | 15.6 | 9.8 | 2.9 | 1.8 | 1.73 |
| Matt Cain | LON | sp | 23 | 13 | 10 | 9 | 7 | 7 | 2 | 7 | 7 | 0 | 8.5 | 3.8 | 12.6 | 7.7 | 0.8 | 2.0 | 1.36 |
| Kiko Calero |   | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.8 | 5.8 | 11.6 | 13.5 | 0.0 | 2.3 | 1.29 |
| Kevin Cameron |   | mr | 28 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 9.0 | 5.4 | 14.4 | 4.5 | 0.0 | 0.8 | 1.60 |
| Shawn Camp |   | mr | 32 | 3 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 0 | 9.2 | 2.5 | 12.1 | 7.1 | 0.5 | 2.8 | 1.30 |
| Jorge Campillo | WIZ | sp | 29 | 8 | 2 | 2 | 1 | 2 | 0 | 9 | 5 | 0 | 9.0 | 2.2 | 11.2 | 6.1 | 1.0 | 2.8 | 1.24 |
| Jose Capellan |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 0.0 | 13.5 | 9.0 | 0.0 | 99.0 | 1.50 |
| Matt Capps | MUL | cl | 24 | 4 | 1 | 0 | 2 | 0 | 0 | 2 | 0 | 1 | 7.9 | 0.8 | 9.1 | 6.5 | 0.8 | 7.8 | 0.97 |
| Jesse Carlson* | BON | mr | 27 | 1 | 3 | 7 | 3 | 2 | 1 | 1 | 3 | 0 | 6.1 | 3.1 | 9.8 | 8.3 | 0.9 | 2.6 | 1.03 |
| Buddy Carlyle | LON | mr | 30 | 5 | 1 | 6 | 1 | 4 | 1 | 4 | 0 | 0 | 7.5 | 3.7 | 11.3 | 8.5 | 0.7 | 2.3 | 1.24 |
| Fausto Carmona |   | sp | 24 | 6 | 1 | 0 | 9 | 8 | 1 | 1 | 4 | 0 | 9.4 | 5.2 | 15.3 | 4.3 | 0.5 | 0.8 | 1.62 |
| Andrew Carpenter |   | mr | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 9.0 | 9.0 | 18.0 | 9.0 | 0.0 | 1.0 | 2.00 |
| Chris Carpenter | TON | sp | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 9.4 | 2.3 | 11.7 | 4.1 | 0.0 | 1.8 | 1.30 |
| D.J. Carrasco |   | mr | 31 | 3 | 2 | 1 | 5 | 0 | 0 | 1 | 1 | 0 | 7.0 | 3.3 | 11.4 | 7.0 | 0.5 | 2.1 | 1.14 |
| Santiago Casilla | OTR | mr | 27 | 9 | 0 | 2 | 3 | 6 | 0 | 3 | 2 | 0 | 10.7 | 3.6 | 14.8 | 7.7 | 0.9 | 2.2 | 1.59 |
| Jack Cassel |   | mr | 27 | 0 | 1 | 2 | 1 | 2 | 1 | 1 | 0 | 0 | 11.3 | 2.4 | 13.9 | 4.2 | 1.5 | 1.8 | 1.52 |
| Alberto Castillo* |   | mr | 32 | 2 | 0 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 9.3 | 3.5 | 15.2 | 8.0 | 1.0 | 2.3 | 1.42 |
| Shawn Chacon |   | sp | 30 | 2 | 3 | 5 | 2 | 2 | 0 | 4 | 1 | 0 | 9.2 | 4.3 | 13.8 | 5.6 | 1.7 | 1.3 | 1.51 |
| Joba Chamberlain | BT | mr | 22 | 8 | 4 | 3 | 2 | 4 | 2 | 2 | 1 | 0 | 7.8 | 3.5 | 11.5 | 10.6 | 0.4 | 3.0 | 1.26 |
| Jesse Chavez |   | mr | 24 | 3 | 0 | 2 | 0 | 2 | 0 | 3 | 1 | 0 | 12.0 | 5.4 | 17.4 | 9.6 | 1.2 | 1.8 | 1.93 |
| Rocky Cherry |   | mr | 28 | 1 | 1 | 3 | 1 | 4 | 0 | 1 | 2 | 0 | 7.9 | 8.5 | 16.9 | 7.9 | 1.6 | 0.9 | 1.82 |
| Matt Chico* |   | sp | 25 | 2 | 2 | 1 | 1 | 1 | 0 | 4 | 2 | 0 | 11.8 | 3.2 | 15.2 | 5.8 | 1.9 | 1.8 | 1.67 |
| Vinnie Chulk |   | mr | 29 | 1 | 0 | 2 | 2 | 1 | 0 | 1 | 1 | 0 | 9.4 | 2.3 | 12.2 | 4.5 | 1.7 | 2.0 | 1.29 |
| Tyler Clippard |   | sp | 23 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 10.5 | 6.1 | 16.5 | 7.0 | 1.7 | 1.1 | 1.84 |
| Todd Coffey |   | mr | 27 | 2 | 1 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 10.5 | 2.7 | 13.5 | 5.1 | 1.3 | 1.9 | 1.46 |
| Phil Coke* |   | mr | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.9 | 1.2 | 6.1 | 8.6 | 0.0 | 7.0 | 0.68 |
| Jesus Colome |   | mr | 30 | 8 | 3 | 4 | 4 | 7 | 0 | 7 | 2 | 0 | 7.7 | 4.9 | 13.2 | 7.0 | 0.8 | 1.4 | 1.41 |
| Bartolo Colon |   | sp | 35 | 0 | 0 | 0 | 2 | 0 | 0 | 3 | 2 | 0 | 10.2 | 2.3 | 12.9 | 6.2 | 1.2 | 2.7 | 1.38 |
| Clay Condrey |   | mr | 32 | 3 | 3 | 8 | 2 | 1 | 0 | 1 | 0 | 0 | 11.1 | 2.5 | 13.8 | 4.4 | 0.8 | 1.8 | 1.51 |
| Jose Contreras |   | sp | 36 | 16 | 1 | 0 | 3 | 6 | 0 | 4 | 2 | 0 | 9.7 | 2.6 | 12.5 | 5.2 | 0.9 | 2.0 | 1.36 |
| Aaron Cook | MAD | sp | 29 | 5 | 8 | 2 | 4 | 6 | 0 | 9 | 4 | 0 | 10.1 | 2.0 | 12.3 | 4.1 | 0.6 | 2.0 | 1.34 |
| Roy Corcoran | EDG | mr | 28 | 1 | 0 | 4 | 2 | 3 | 0 | 3 | 3 | 0 | 8.1 | 4.5 | 12.8 | 4.8 | 0.1 | 1.1 | 1.39 |
| Chad Cordero |   | mr | 26 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 12.5 | 6.2 | 18.7 | 10.4 | 0.0 | 1.7 | 2.08 |
| Francisco Cordero | CRH | cl | 33 | 7 | 3 | 3 | 3 | 3 | 0 | 3 | 3 | 0 | 7.8 | 4.9 | 13.1 | 10.0 | 0.8 | 2.1 | 1.41 |
| Bryan Corey |   | mr | 34 | 2 | 1 | 4 | 0 | 2 | 1 | 3 | 2 | 0 | 10.6 | 2.4 | 13.0 | 4.4 | 1.6 | 1.8 | 1.44 |
| Lance Cormier |   | mr | 27 | 6 | 2 | 3 | 1 | 2 | 1 | 1 | 3 | 0 | 9.8 | 4.3 | 14.2 | 5.8 | 0.5 | 1.4 | 1.56 |
| Manuel Corpas |   | mr | 25 | 2 | 0 | 4 | 2 | 1 | 0 | 6 | 1 | 0 | 10.5 | 2.6 | 13.3 | 5.6 | 0.8 | 2.2 | 1.46 |
| Kevin Correia | MUL | sp | 27 | 4 | 7 | 3 | 4 | 5 | 0 | 3 | 5 | 0 | 11.5 | 3.8 | 15.7 | 5.4 | 1.2 | 1.4 | 1.71 |
| Neal Cotts* | CRH | mr | 28 | 3 | 0 | 2 | 1 | 3 | 0 | 3 | 0 | 0 | 9.6 | 3.3 | 13.1 | 10.9 | 1.8 | 3.3 | 1.43 |
| Jesse Crain | BON | mr | 26 | 6 | 1 | 3 | 1 | 2 | 0 | 0 | 2 | 0 | 8.9 | 3.4 | 12.5 | 7.2 | 0.9 | 2.1 | 1.37 |
| Francisco Cruceta |   | mr | 26 | 1 | 0 | 1 | 0 | 3 | 0 | 2 | 0 | 0 | 10.0 | 7.7 | 17.7 | 8.5 | 1.5 | 1.1 | 1.97 |
| Juan Cruz | TON | mr | 29 | 5 | 5 | 0 | 3 | 1 | 0 | 2 | 2 | 0 | 5.9 | 5.4 | 11.8 | 12.4 | 0.9 | 2.3 | 1.26 |
| Johnny Cueto | Pal | sp | 22 | 7 | 6 | 1 | 14 | 6 | 1 | 9 | 5 | 0 | 9.2 | 3.5 | 13.4 | 8.2 | 1.5 | 2.3 | 1.41 |
| John Danks* | EDG | sp | 23 | 23 | 8 | 1 | 4 | 7 | 0 | 2 | 2 | 0 | 8.4 | 2.6 | 11.2 | 7.3 | 0.7 | 2.8 | 1.23 |
| Kyle Davies |   | sp | 24 | 8 | 1 | 0 | 2 | 8 | 1 | 1 | 3 | 0 | 9.6 | 3.4 | 13.2 | 5.7 | 0.8 | 1.7 | 1.45 |
| Doug Davis* |   | sp | 32 | 8 | 3 | 4 | 4 | 7 | 0 | 10 | 4 | 0 | 9.9 | 3.9 | 14.1 | 6.9 | 0.8 | 1.8 | 1.53 |
| Jason Davis |   | mr | 28 | 5 | 1 | 0 | 3 | 5 | 0 | 3 | 3 | 0 | 10.1 | 4.5 | 15.4 | 3.4 | 0.5 | 0.8 | 1.62 |
| Eulogio De La Cruz |   | mr | 24 | 3 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 15.0 | 11.0 | 26.0 | 4.0 | 2.0 | 0.4 | 2.89 |
| Jorge De La Rosa* | MUL | sp | 27 | 13 | 5 | 3 | 7 | 14 | 1 | 6 | 7 | 0 | 8.9 | 4.3 | 13.6 | 8.9 | 0.9 | 2.1 | 1.46 |
| Valerio de los Santos* |   | sp | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 12.4 | 19.1 | 11.3 | 1.1 | 0.9 | 2.13 |
| Manny Delcarmen | GEO | mr | 26 | 7 | 0 | 1 | 3 | 0 | 0 | 4 | 4 | 0 | 6.7 | 3.4 | 10.4 | 8.7 | 0.6 | 2.6 | 1.12 |
| Jesus Delgado |   | mr | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 4.5 | 13.5 | 18.0 | 0.0 | 0.0 | 0.0 | 2.00 |
| Ryan Dempster | CRH | sp | 31 | 11 | 4 | 1 | 7 | 5 | 0 | 4 | 3 | 0 | 7.6 | 3.3 | 11.2 | 8.1 | 0.6 | 2.5 | 1.21 |
| Matt DeSalvo |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 49.5 | 9.0 | 58.5 | 9.0 | 0.0 | 1.0 | 6.50 |
| Elmer Dessens |   | mr | 37 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 22.5 | 9.0 | 31.5 | 4.5 | 2.3 | 0.5 | 3.50 |
| Joey Devine | BT | mr | 24 | 3 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 4.5 | 3.0 | 7.5 | 9.7 | 0.0 | 3.3 | 0.83 |
| Joselo Diaz |   | mr | 28 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 9.0 | 9.0 | 27.0 | 18.0 | 0.0 | 2.0 | 2.00 |
| R.A. Dickey | OTR | mr | 33 | 6 | 7 | 4 | 2 | 11 | 1 | 4 | 6 | 0 | 9.9 | 4.1 | 14.2 | 4.6 | 1.2 | 1.1 | 1.56 |
| Mark DiFelice |   | mr | 31 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 8.1 | 1.9 | 9.9 | 9.5 | 1.9 | 5.0 | 1.11 |
| Tim Dillard |   | mr | 24 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 1 | 0 | 10.7 | 3.8 | 14.4 | 3.1 | 1.3 | 0.8 | 1.60 |
| Lenny DiNardo* |   | mr | 28 | 2 | 0 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 12.1 | 5.1 | 18.0 | 4.7 | 1.2 | 0.9 | 1.91 |
| Scott Dohmann |   | mr | 30 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 11.0 | 4.3 | 15.3 | 7.4 | 1.2 | 1.7 | 1.70 |
| Freddy Dolsi |   | mr | 25 | 10 | 2 | 5 | 3 | 4 | 1 | 0 | 0 | 0 | 9.4 | 5.3 | 15.3 | 5.5 | 0.6 | 1.0 | 1.64 |
| Brendan Donnelly |   | mr | 36 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 13.2 | 6.6 | 19.8 | 5.3 | 1.3 | 0.8 | 2.20 |
| Octavio Dotel |   | mr | 34 | 16 | 1 | 3 | 5 | 4 | 0 | 4 | 0 | 0 | 7.0 | 3.9 | 11.6 | 12.4 | 1.6 | 3.2 | 1.21 |
| Scott Downs* | EDG | mr | 32 | 2 | 0 | 7 | 4 | 3 | 0 | 5 | 0 | 0 | 6.9 | 3.4 | 10.8 | 7.3 | 0.4 | 2.1 | 1.15 |
| Justin Duchscherer | COP | sp | 30 | 4 | 2 | 2 | 8 | 1 | 0 | 1 | 4 | 0 | 6.8 | 2.2 | 9.5 | 6.0 | 0.7 | 2.8 | 1.00 |
| Brandon Duckworth |   | sp | 32 | 3 | 3 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 9.0 | 4.5 | 14.2 | 4.7 | 0.5 | 1.1 | 1.50 |
| Zach Duke* |   | sp | 25 | 6 | 6 | 1 | 7 | 2 | 2 | 14 | 4 | 0 | 11.2 | 2.3 | 13.8 | 4.2 | 0.9 | 1.9 | 1.50 |
| Phil Dumatrait* |   | sp | 26 | 2 | 2 | 2 | 2 | 1 | 0 | 1 | 3 | 0 | 9.4 | 4.8 | 14.4 | 5.9 | 0.8 | 1.2 | 1.58 |
| Chad Durbin | MAD | mr | 30 | 3 | 4 | 7 | 4 | 3 | 0 | 4 | 2 | 1 | 8.3 | 3.6 | 12.3 | 6.5 | 0.5 | 1.8 | 1.32 |
| Adam Eaton |   | sp | 30 | 4 | 5 | 5 | 6 | 2 | 0 | 3 | 2 | 0 | 11.0 | 3.7 | 15.2 | 4.8 | 1.3 | 1.3 | 1.64 |
| Mike Ekstrom |   | mr | 24 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 13.0 | 6.5 | 19.6 | 5.6 | 1.9 | 0.9 | 2.17 |
| Scott Elarton |   | mr | 32 | 1 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 9.4 | 5.3 | 14.7 | 8.8 | 0.0 | 1.7 | 1.63 |
| Scott Elbert* |   | mr | 22 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 13.5 | 6.0 | 21.0 | 12.0 | 3.0 | 2.0 | 2.17 |
| Alan Embree* |   | mr | 38 | 6 | 1 | 5 | 2 | 2 | 0 | 2 | 3 | 0 | 8.6 | 4.4 | 13.3 | 8.3 | 1.2 | 1.9 | 1.44 |
| Geno Espineli* |   | mr | 25 | 2 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 9.6 | 4.5 | 14.1 | 4.5 | 2.8 | 1.0 | 1.56 |
| Shawn Estes* |   | sp | 35 | 6 | 1 | 0 | 2 | 2 | 0 | 2 | 0 | 0 | 10.3 | 3.7 | 14.4 | 3.9 | 1.2 | 1.1 | 1.56 |
| Marco Estrada |   | mr | 24 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 12.1 | 3.6 | 17.1 | 7.1 | 2.8 | 2.0 | 1.74 |
| Dana Eveland* |   | sp | 24 | 13 | 4 | 2 | 12 | 6 | 1 | 2 | 5 | 1 | 9.2 | 4.1 | 14.0 | 6.3 | 0.5 | 1.5 | 1.48 |
| Scott Eyre* |   | mr | 36 | 4 | 0 | 2 | 2 | 1 | 0 | 0 | 2 | 0 | 8.1 | 2.5 | 11.2 | 11.2 | 0.7 | 4.6 | 1.17 |
| Brian Falkenborg |   | mr | 30 | 2 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 10.5 | 4.8 | 15.3 | 7.7 | 1.6 | 1.6 | 1.70 |
| Kyle Farnsworth |   | mr | 32 | 6 | 7 | 4 | 1 | 1 | 1 | 3 | 1 | 0 | 10.4 | 3.3 | 13.9 | 9.1 | 2.2 | 2.8 | 1.52 |
| Ryan Feierabend* |   | sp | 22 | 1 | 4 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 13.4 | 3.2 | 16.8 | 5.9 | 1.6 | 1.9 | 1.84 |
| Scott Feldman | MID | sp | 25 | 22 | 5 | 2 | 10 | 4 | 2 | 1 | 9 | 0 | 9.6 | 3.3 | 13.5 | 4.4 | 1.3 | 1.3 | 1.43 |
| Pedro Feliciano* | MAD | mr | 31 | 0 | 0 | 8 | 3 | 2 | 0 | 2 | 3 | 0 | 9.6 | 4.4 | 14.5 | 8.4 | 1.2 | 1.9 | 1.56 |
| Nelson Figueroa |   | mr | 34 | 3 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 0 | 9.5 | 5.2 | 15.1 | 7.1 | 0.6 | 1.4 | 1.63 |
| Randy Flores* |   | mr | 32 | 4 | 0 | 3 | 1 | 1 | 0 | 0 | 2 | 0 | 11.9 | 7.0 | 19.3 | 6.0 | 0.7 | 0.9 | 2.10 |
| Gavin Floyd | TON | sp | 25 | 37 | 5 | 6 | 9 | 9 | 0 | 7 | 5 | 0 | 8.3 | 3.1 | 11.7 | 6.3 | 1.3 | 2.1 | 1.26 |
| Josh Fogg |   | sp | 31 | 3 | 2 | 1 | 6 | 1 | 0 | 6 | 2 | 0 | 11.1 | 3.1 | 14.9 | 5.2 | 2.0 | 1.7 | 1.58 |
| Casey Fossum* |   | mr | 30 | 0 | 1 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 9.6 | 3.9 | 14.2 | 6.1 | 0.9 | 1.6 | 1.50 |
| Keith Foulke |   | mr | 35 | 3 | 1 | 2 | 1 | 1 | 0 | 1 | 2 | 0 | 8.1 | 3.8 | 12.2 | 6.7 | 2.0 | 1.8 | 1.32 |
| Chad Fox |   | mr | 37 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 5.4 | 8.1 | 13.5 | 2.7 | 2.7 | 0.3 | 1.50 |
| Jeff Francis* |   | sp | 27 | 9 | 2 | 4 | 3 | 0 | 0 | 6 | 4 | 0 | 10.3 | 3.1 | 13.5 | 5.9 | 1.3 | 1.9 | 1.48 |
| Frank Francisco | EDG | mr | 28 | 7 | 1 | 2 | 0 | 5 | 0 | 0 | 3 | 0 | 6.7 | 3.7 | 10.4 | 11.8 | 1.0 | 3.2 | 1.15 |
| Ryan Franklin |   | mr | 35 | 2 | 1 | 4 | 3 | 3 | 0 | 2 | 2 | 0 | 9.8 | 3.4 | 13.6 | 5.8 | 1.1 | 1.7 | 1.47 |
| Jason Frasor | MID | mr | 30 | 5 | 2 | 4 | 1 | 6 | 0 | 0 | 2 | 0 | 6.8 | 6.1 | 13.1 | 8.0 | 0.8 | 1.3 | 1.44 |
| Brian Fuentes* | CCL | cl | 32 | 4 | 1 | 1 | 1 | 1 | 0 | 3 | 1 | 0 | 6.8 | 3.2 | 10.1 | 11.8 | 0.4 | 3.7 | 1.10 |
| Kazuo Fukumori |   | mr | 31 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 24.8 | 9.0 | 33.8 | 2.3 | 4.5 | 0.3 | 3.75 |
| Jeff Fulchino |   | mr | 28 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 13.5 | 5.1 | 19.3 | 7.7 | 1.3 | 1.5 | 2.07 |
| Kason Gabbard* |   | sp | 26 | 2 | 0 | 4 | 1 | 4 | 0 | 2 | 2 | 0 | 10.3 | 6.3 | 16.7 | 5.3 | 0.8 | 0.8 | 1.84 |
| Eric Gagne |   | mr | 32 | 0 | 0 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 8.9 | 4.3 | 13.6 | 7.4 | 2.1 | 1.7 | 1.47 |
| Armando Galarraga |   | sp | 26 | 7 | 1 | 2 | 6 | 6 | 0 | 2 | 4 | 0 | 7.7 | 3.1 | 11.0 | 6.3 | 1.4 | 2.1 | 1.19 |
| Sean Gallagher |   | sp | 22 | 5 | 4 | 2 | 6 | 2 | 0 | 3 | 6 | 0 | 9.2 | 4.5 | 14.2 | 8.0 | 1.0 | 1.8 | 1.53 |
| Yovani Gallardo | LON | sp | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 8.3 | 3.0 | 11.3 | 7.5 | 1.1 | 2.5 | 1.25 |
| Freddy Garcia |   | sp | 32 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.6 | 3.6 | 10.8 | 7.2 | 1.8 | 2.0 | 1.13 |
| Jaime Garcia* |   | mr | 21 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 7.9 | 4.5 | 12.9 | 4.5 | 2.3 | 1.0 | 1.38 |
| Lee Gardner |   | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 18.9 | 5.4 | 24.3 | 5.4 | 2.7 | 1.0 | 2.70 |
| Jon Garland |   | sp | 28 | 3 | 3 | 4 | 8 | 4 | 0 | 8 | 8 | 0 | 10.8 | 2.7 | 13.9 | 4.1 | 1.1 | 1.5 | 1.51 |
| Matt Garza | GEO | sp | 24 | 5 | 1 | 2 | 6 | 3 | 2 | 3 | 9 | 0 | 8.3 | 2.9 | 11.5 | 6.2 | 0.9 | 2.2 | 1.24 |
| Chad Gaudin |   | mr | 25 | 1 | 3 | 3 | 3 | 2 | 2 | 2 | 2 | 1 | 9.2 | 2.7 | 12.2 | 7.1 | 1.1 | 2.6 | 1.32 |
| Geoff Geary | TON | mr | 31 | 0 | 0 | 5 | 2 | 0 | 1 | 3 | 1 | 0 | 6.3 | 3.9 | 10.5 | 6.3 | 0.4 | 1.6 | 1.14 |
| Josh Geer |   | sp | 25 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 9.7 | 3.0 | 12.7 | 5.3 | 0.7 | 1.8 | 1.41 |
| Franklyn German |   | mr | 28 | 2 | 2 | 1 | 0 | 1 | 0 | 3 | 3 | 0 | 7.5 | 5.4 | 12.9 | 6.2 | 0.0 | 1.2 | 1.43 |
| Justin Germano |   | sp | 25 | 9 | 2 | 2 | 1 | 4 | 0 | 2 | 1 | 0 | 11.1 | 2.7 | 14.0 | 3.5 | 1.6 | 1.3 | 1.53 |
| Dan Giese | BON | mr | 31 | 9 | 1 | 1 | 1 | 1 | 0 | 0 | 3 | 0 | 8.1 | 2.9 | 11.2 | 6.0 | 0.6 | 2.1 | 1.22 |
| Matt Ginter |   | sp | 30 | 1 | 0 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 10.7 | 1.3 | 12.0 | 5.1 | 1.3 | 4.0 | 1.33 |
| Tom Glavine* |   | sp | 42 | 1 | 4 | 4 | 1 | 0 | 0 | 7 | 3 | 0 | 9.5 | 5.3 | 14.9 | 5.3 | 1.6 | 1.0 | 1.64 |
| Gary Glover |   | mr | 31 | 0 | 1 | 6 | 2 | 4 | 0 | 1 | 0 | 0 | 10.6 | 3.6 | 14.6 | 6.1 | 1.2 | 1.7 | 1.58 |
| Jimmy Gobble* |   | mr | 26 | 2 | 0 | 1 | 2 | 6 | 0 | 0 | 1 | 0 | 11.1 | 6.5 | 18.2 | 7.7 | 1.4 | 1.2 | 1.96 |
| Edgar Gonzalez |   | mr | 25 | 2 | 1 | 2 | 3 | 4 | 0 | 4 | 1 | 0 | 10.9 | 3.9 | 15.4 | 6.0 | 1.5 | 1.5 | 1.65 |
| Enrique Gonzalez |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.8 | 5.4 | 16.2 | 2.7 | 0.0 | 0.5 | 1.80 |
| Gio Gonzalez* |   | sp | 22 | 0 | 2 | 1 | 3 | 1 | 0 | 2 | 1 | 0 | 8.5 | 6.6 | 15.9 | 9.0 | 2.4 | 1.4 | 1.68 |
| Mike Gonzalez* |   | cl | 30 | 1 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 0 | 7.0 | 3.7 | 11.0 | 11.8 | 1.6 | 3.1 | 1.19 |
| Brian Gordon |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 2.3 | 0.0 | 99.0 | 1.00 |
| Tom Gordon |   | mr | 40 | 1 | 0 | 1 | 0 | 4 | 0 | 0 | 1 | 0 | 9.4 | 5.2 | 14.6 | 7.9 | 0.9 | 1.5 | 1.62 |
| Tom Gorzelanny* |   | sp | 25 | 16 | 4 | 0 | 1 | 5 | 1 | 3 | 6 | 0 | 10.3 | 6.0 | 16.3 | 5.7 | 1.7 | 1.0 | 1.80 |
| John Grabow* | TON | mr | 29 | 3 | 2 | 2 | 1 | 4 | 2 | 3 | 2 | 0 | 7.1 | 4.4 | 11.6 | 7.3 | 1.1 | 1.7 | 1.28 |
| Jeff Gray |   | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 15.4 | 1.9 | 19.3 | 7.7 | 1.9 | 4.0 | 1.93 |
| Sean Green |   | mr | 29 | 3 | 1 | 1 | 6 | 5 | 1 | 3 | 7 | 0 | 9.1 | 4.1 | 13.9 | 7.1 | 0.3 | 1.7 | 1.47 |
| Kevin Gregg | BT | cl | 30 | 6 | 2 | 4 | 4 | 7 | 0 | 3 | 1 | 0 | 6.7 | 4.8 | 12.1 | 7.6 | 0.4 | 1.6 | 1.28 |
| Zack Greinke | COP | sp | 24 | 2 | 4 | 1 | 4 | 8 | 1 | 2 | 4 | 0 | 9.0 | 2.5 | 11.7 | 8.1 | 0.9 | 3.3 | 1.28 |
| Jason Grilli | COP | mr | 31 | 4 | 2 | 7 | 2 | 4 | 0 | 1 | 3 | 0 | 8.0 | 4.6 | 12.8 | 8.3 | 0.2 | 1.8 | 1.40 |
| Eddie Guardado* |   | mr | 37 | 3 | 0 | 2 | 0 | 1 | 0 | 2 | 2 | 0 | 8.0 | 3.0 | 11.0 | 5.3 | 0.6 | 1.7 | 1.22 |
| Matt Guerrier | MID | mr | 29 | 8 | 1 | 9 | 0 | 2 | 0 | 1 | 1 | 0 | 9.9 | 4.4 | 14.3 | 7.0 | 1.4 | 1.6 | 1.59 |
| Carlos Guevara |   | mr | 26 | 3 | 0 | 2 | 0 | 3 | 0 | 1 | 1 | 0 | 9.5 | 6.6 | 16.1 | 8.0 | 1.5 | 1.2 | 1.78 |
| Jeremy Guthrie | MID | sp | 29 | 13 | 4 | 2 | 7 | 3 | 0 | 2 | 2 | 0 | 8.3 | 2.7 | 11.4 | 5.7 | 1.1 | 2.1 | 1.23 |
| Angel Guzman |   | mr | 26 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 9.3 | 3.7 | 14.0 | 9.3 | 0.9 | 2.5 | 1.45 |
| Charlie Haeger |   | mr | 24 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 16.6 | 10.4 | 31.2 | 8.3 | 4.2 | 0.8 | 3.00 |
| Roy Halladay | ROK | sp | 31 | 15 | 5 | 3 | 12 | 4 | 0 | 5 | 4 | 0 | 8.0 | 1.4 | 9.9 | 7.5 | 0.7 | 5.3 | 1.05 |
| Cole Hamels* | BT | sp | 24 | 15 | 2 | 7 | 1 | 0 | 0 | 6 | 2 | 1 | 7.6 | 2.1 | 9.8 | 7.8 | 1.1 | 3.7 | 1.08 |
| Jason Hammel | EDG | mr | 25 | 11 | 1 | 4 | 2 | 7 | 0 | 2 | 2 | 0 | 9.5 | 4.0 | 13.8 | 5.1 | 1.3 | 1.3 | 1.51 |
| Justin Hampson* |   | mr | 28 | 3 | 1 | 2 | 0 | 0 | 0 | 1 | 4 | 0 | 9.1 | 2.9 | 12.0 | 5.6 | 0.3 | 1.9 | 1.34 |
| Mike Hampton* |   | sp | 35 | 4 | 4 | 6 | 1 | 0 | 0 | 5 | 2 | 0 | 9.6 | 3.2 | 12.9 | 4.4 | 1.2 | 1.4 | 1.42 |
| Joel Hanrahan | CCL | mr | 26 | 11 | 0 | 7 | 1 | 6 | 0 | 2 | 6 | 0 | 7.8 | 4.5 | 12.4 | 9.9 | 1.0 | 2.2 | 1.36 |
| Devern Hansack |   | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.1 | 1.3 | 9.4 | 6.8 | 0.0 | 5.0 | 1.05 |
| Craig Hansen |   | mr | 24 | 4 | 1 | 2 | 2 | 6 | 0 | 2 | 1 | 0 | 7.8 | 8.4 | 16.5 | 6.2 | 0.6 | 0.7 | 1.79 |
| J.A. Happ* |   | sp | 25 | 1 | 0 | 1 | 1 | 1 | 0 | 2 | 1 | 0 | 8.0 | 4.0 | 12.2 | 7.4 | 0.9 | 1.9 | 1.33 |
| Aaron Harang | GEO | sp | 30 | 17 | 4 | 5 | 2 | 2 | 0 | 11 | 7 | 0 | 10.0 | 2.4 | 12.5 | 7.5 | 1.7 | 3.1 | 1.38 |
| Rich Harden | COP | sp | 26 | 7 | 7 | 2 | 3 | 3 | 0 | 2 | 3 | 0 | 5.8 | 3.7 | 9.7 | 11.0 | 0.7 | 3.0 | 1.06 |
| Dan Haren | LON | sp | 27 | 9 | 2 | 4 | 6 | 11 | 0 | 7 | 3 | 0 | 8.5 | 1.7 | 10.4 | 8.6 | 0.8 | 5.2 | 1.13 |
| Matt Harrison* |   | sp | 22 | 3 | 3 | 2 | 2 | 2 | 2 | 1 | 5 | 0 | 10.8 | 3.3 | 14.3 | 4.5 | 1.3 | 1.4 | 1.57 |
| Kevin Hart |   | mr | 25 | 4 | 0 | 3 | 3 | 1 | 0 | 1 | 0 | 0 | 12.7 | 5.9 | 19.5 | 7.5 | 0.7 | 1.3 | 2.06 |
| LaTroy Hawkins |   | mr | 35 | 2 | 2 | 4 | 0 | 3 | 0 | 1 | 3 | 0 | 7.7 | 3.2 | 10.9 | 7.0 | 0.4 | 2.2 | 1.21 |
| Dirk Hayhurst |   | mr | 27 | 5 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 14.6 | 5.4 | 20.0 | 7.6 | 1.1 | 1.4 | 2.22 |
| Aaron Heilman |   | mr | 29 | 2 | 0 | 8 | 9 | 2 | 0 | 8 | 2 | 0 | 8.9 | 5.4 | 15.4 | 9.5 | 1.2 | 1.7 | 1.59 |
| Mark Hendrickson* |   | sp | 34 | 16 | 3 | 7 | 5 | 4 | 0 | 9 | 5 | 0 | 10.0 | 3.2 | 13.5 | 5.5 | 1.1 | 1.7 | 1.47 |
| Sean Henn* |   | mr | 27 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 10.6 | 8.7 | 19.3 | 8.7 | 1.0 | 1.0 | 2.14 |
| Brad Hennessey |   | mr | 28 | 4 | 3 | 1 | 1 | 1 | 0 | 3 | 1 | 0 | 14.1 | 3.3 | 17.6 | 4.7 | 1.8 | 1.4 | 1.93 |
| Clay Hensley |   | mr | 28 | 4 | 0 | 3 | 1 | 1 | 0 | 1 | 3 | 0 | 8.3 | 5.8 | 14.3 | 6.0 | 0.5 | 1.0 | 1.56 |
| Matt Herges |   | mr | 38 | 1 | 2 | 5 | 5 | 3 | 1 | 1 | 4 | 0 | 11.1 | 3.4 | 15.1 | 6.4 | 0.7 | 1.9 | 1.60 |
| Felix Hernandez | ROK | sp | 22 | 19 | 4 | 7 | 8 | 8 | 1 | 4 | 6 | 0 | 8.9 | 3.6 | 12.8 | 7.8 | 0.8 | 2.2 | 1.39 |
| Fernando Hernandez |   | mr | 23 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 12.0 | 15.0 | 30.0 | 6.0 | 0.0 | 0.4 | 3.00 |
| Livan Hernandez |   | sp | 33 | 3 | 5 | 4 | 2 | 3 | 1 | 5 | 9 | 0 | 12.8 | 2.1 | 15.1 | 3.3 | 1.3 | 1.6 | 1.67 |
| Runelvys Hernandez |   | sp | 30 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 14.9 | 5.1 | 20.0 | 7.0 | 1.9 | 1.4 | 2.22 |
| Danny Herrera* |   | mr | 23 | 0 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 0 | 12.3 | 3.7 | 18.4 | 9.8 | 1.2 | 2.7 | 1.77 |
| Yoslan Herrera |   | sp | 27 | 1 | 0 | 0 | 1 | 1 | 0 | 3 | 2 | 0 | 17.2 | 5.9 | 23.6 | 4.9 | 0.5 | 0.8 | 2.56 |
| Rich Hill* |   | sp | 28 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.9 | 8.2 | 14.6 | 6.9 | 0.9 | 0.8 | 1.58 |
| Shawn Hill |   | sp | 27 | 8 | 3 | 2 | 1 | 2 | 1 | 3 | 3 | 0 | 12.5 | 3.3 | 15.9 | 5.5 | 0.7 | 1.7 | 1.75 |
| Mike Hinckley* |   | mr | 25 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 5.3 | 2.0 | 7.9 | 5.9 | 0.0 | 3.0 | 0.80 |
| Alex Hinshaw* |   | mr | 25 | 1 | 1 | 4 | 3 | 5 | 0 | 4 | 2 | 0 | 7.0 | 6.6 | 14.3 | 10.7 | 1.1 | 1.6 | 1.51 |
| Jason Hirsh |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.6 | 4.2 | 19.7 | 6.2 | 3.1 | 1.5 | 2.19 |
| Luke Hochevar |   | sp | 24 | 14 | 4 | 1 | 5 | 7 | 0 | 1 | 2 | 0 | 10.0 | 3.3 | 13.6 | 5.0 | 0.8 | 1.5 | 1.47 |
| Trevor Hoffman | Pal | cl | 40 | 3 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 7.5 | 1.8 | 9.3 | 9.1 | 1.6 | 5.1 | 1.04 |
| J.P. Howell* | MID | mr | 25 | 10 | 3 | 1 | 4 | 5 | 0 | 6 | 1 | 0 | 6.2 | 3.9 | 10.6 | 9.3 | 0.6 | 2.4 | 1.13 |
| Bob Howry | WIZ | mr | 34 | 5 | 0 | 5 | 2 | 0 | 0 | 1 | 4 | 0 | 11.5 | 1.7 | 13.4 | 7.5 | 1.7 | 4.5 | 1.46 |
| Tim Hudson | GEO | sp | 32 | 6 | 4 | 5 | 2 | 3 | 1 | 5 | 4 | 0 | 7.9 | 2.5 | 10.6 | 5.4 | 0.7 | 2.1 | 1.16 |
| Phil Hughes | COP | sp | 22 | 8 | 0 | 0 | 1 | 2 | 0 | 1 | 3 | 0 | 11.4 | 4.0 | 15.6 | 6.1 | 0.8 | 1.5 | 1.71 |
| Philip Humber |   | mr | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.5 | 3.9 | 13.1 | 4.6 | 3.1 | 1.2 | 1.37 |
| Tommy Hunter |   | sp | 21 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 18.8 | 2.5 | 22.1 | 7.4 | 3.3 | 3.0 | 2.36 |
| Eric Hurley |   | sp | 22 | 0 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 9.5 | 3.3 | 13.1 | 4.7 | 1.8 | 1.4 | 1.42 |
| Kei Igawa* |   | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 29.3 | 0.0 | 29.3 | 0.0 | 0.0 | 0.0 | 3.25 |
| Jason Isringhausen |   | cl | 35 | 6 | 2 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 10.1 | 4.6 | 15.8 | 7.6 | 1.1 | 1.6 | 1.64 |
| Edwin Jackson |   | sp | 24 | 12 | 6 | 1 | 2 | 7 | 1 | 3 | 3 | 0 | 9.8 | 3.8 | 13.6 | 5.3 | 1.1 | 1.4 | 1.51 |
| Zach Jackson* |   | sp | 25 | 1 | 0 | 0 | 3 | 2 | 0 | 1 | 1 | 0 | 10.6 | 2.5 | 13.6 | 4.8 | 1.1 | 1.9 | 1.46 |
| Chuck James* |   | sp | 26 | 5 | 0 | 2 | 3 | 1 | 1 | 4 | 3 | 0 | 10.9 | 6.1 | 17.9 | 6.7 | 3.0 | 1.1 | 1.89 |
| Bobby Jenks | OTR | cl | 27 | 5 | 0 | 4 | 1 | 3 | 0 | 2 | 1 | 0 | 7.4 | 2.5 | 10.1 | 5.5 | 0.4 | 2.2 | 1.10 |
| Jason Jennings |   | sp | 29 | 0 | 1 | 2 | 1 | 1 | 0 | 2 | 0 | 0 | 11.5 | 5.9 | 17.8 | 4.0 | 2.6 | 0.7 | 1.94 |
| Kevin Jepsen |   | mr | 23 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 8.6 | 4.3 | 13.0 | 7.6 | 0.0 | 1.8 | 1.44 |
| Cesar Jimenez* |   | mr | 23 | 1 | 3 | 0 | 1 | 2 | 0 | 2 | 1 | 0 | 8.4 | 3.4 | 12.1 | 6.8 | 0.5 | 2.0 | 1.31 |
| Kelvin Jimenez |   | mr | 27 | 2 | 0 | 0 | 1 | 3 | 0 | 1 | 1 | 0 | 10.5 | 5.6 | 16.5 | 4.1 | 1.9 | 0.7 | 1.79 |
| Ubaldo Jimenez | TON | sp | 24 | 19 | 3 | 4 | 10 | 16 | 0 | 7 | 4 | 0 | 8.2 | 4.7 | 13.4 | 7.8 | 0.5 | 1.7 | 1.43 |
| Jason Johnson |   | mr | 34 | 1 | 0 | 3 | 2 | 3 | 0 | 1 | 0 | 0 | 9.8 | 3.7 | 14.1 | 6.1 | 1.5 | 1.7 | 1.50 |
| Jim Johnson | GEO | mr | 25 | 3 | 2 | 3 | 3 | 1 | 1 | 2 | 1 | 0 | 7.1 | 3.7 | 11.1 | 5.0 | 0.0 | 1.4 | 1.19 |
| Josh Johnson | LON | sp | 24 | 5 | 2 | 1 | 1 | 4 | 0 | 5 | 1 | 0 | 9.4 | 2.8 | 12.3 | 7.9 | 0.7 | 2.9 | 1.35 |
| Randy Johnson* | ROK | sp | 44 | 21 | 3 | 6 | 6 | 2 | 1 | 13 | 6 | 0 | 9.0 | 2.2 | 11.4 | 8.5 | 1.2 | 3.9 | 1.24 |
| Todd Jones |   | cl | 40 | 2 | 0 | 3 | 4 | 4 | 0 | 1 | 2 | 0 | 10.8 | 3.9 | 15.6 | 3.0 | 1.1 | 0.8 | 1.63 |
| Jorge Julio |   | mr | 29 | 3 | 0 | 2 | 1 | 6 | 0 | 0 | 2 | 0 | 8.1 | 5.7 | 14.1 | 10.2 | 0.9 | 1.8 | 1.53 |
| Jair Jurrjens | WIZ | sp | 22 | 28 | 3 | 9 | 4 | 3 | 0 | 12 | 5 | 0 | 9.0 | 3.3 | 12.5 | 6.6 | 0.5 | 2.0 | 1.37 |
| Jeff Karstens |   | sp | 25 | 3 | 3 | 0 | 0 | 1 | 0 | 2 | 4 | 0 | 9.8 | 2.3 | 12.1 | 4.0 | 1.2 | 1.8 | 1.34 |
| Scott Kazmir* | GEO | sp | 24 | 7 | 3 | 2 | 4 | 5 | 0 | 4 | 5 | 0 | 7.3 | 4.1 | 11.6 | 9.8 | 1.4 | 2.4 | 1.27 |
| Kyle Kendrick |   | sp | 23 | 15 | 5 | 2 | 14 | 4 | 1 | 8 | 4 | 0 | 11.2 | 3.3 | 15.3 | 3.9 | 1.3 | 1.2 | 1.61 |
| Ian Kennedy |   | sp | 23 | 5 | 2 | 0 | 1 | 3 | 0 | 1 | 4 | 0 | 11.3 | 5.9 | 17.5 | 6.1 | 1.1 | 1.0 | 1.92 |
| Logan Kensing |   | mr | 25 | 11 | 0 | 5 | 4 | 7 | 0 | 1 | 2 | 0 | 8.1 | 5.4 | 14.2 | 8.9 | 1.1 | 1.7 | 1.50 |
| Clayton Kershaw* | MUL | sp | 20 | 5 | 2 | 3 | 1 | 7 | 0 | 3 | 3 | 0 | 9.1 | 4.3 | 13.5 | 8.4 | 0.9 | 1.9 | 1.50 |
| Ray King* |   | mr | 34 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 12.8 | 5.7 | 19.9 | 1.4 | 1.4 | 0.3 | 2.05 |
| Josh Kinney |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 1.3 | 5.1 | 10.3 | 0.0 | 8.0 | 0.57 |
| Brandon Knight |   | sp | 32 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 10.5 | 5.3 | 17.3 | 7.5 | 0.0 | 1.4 | 1.75 |
| Masa Kobayashi |   | mr | 34 | 2 | 0 | 2 | 1 | 4 | 0 | 1 | 1 | 0 | 10.5 | 2.3 | 12.9 | 5.7 | 1.3 | 2.5 | 1.42 |
| Bobby Korecky |   | mr | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.7 | 4.1 | 13.8 | 3.1 | 1.0 | 0.8 | 1.53 |
| Eddie Kunz |   | mr | 22 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 16.9 | 3.4 | 23.6 | 3.4 | 3.4 | 1.0 | 2.25 |
| Hong-Chih Kuo* | Pal | mr | 26 | 2 | 0 | 2 | 3 | 1 | 1 | 4 | 1 | 0 | 6.8 | 2.4 | 9.4 | 10.8 | 0.4 | 4.6 | 1.01 |
| Hiroki Kuroda | WIZ | sp | 33 | 7 | 2 | 8 | 7 | 5 | 0 | 7 | 5 | 0 | 8.9 | 2.1 | 11.3 | 5.7 | 0.6 | 2.8 | 1.22 |
| John Lackey | COP | sp | 29 | 11 | 3 | 1 | 10 | 5 | 0 | 5 | 1 | 0 | 8.9 | 2.2 | 11.6 | 7.2 | 1.4 | 3.3 | 1.23 |
| Aaron Laffey* |   | sp | 23 | 2 | 2 | 1 | 9 | 5 | 1 | 2 | 0 | 0 | 9.9 | 3.0 | 13.7 | 4.1 | 1.0 | 1.4 | 1.43 |
| Chris Lambert |   | mr | 25 | 7 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 13.5 | 3.0 | 17.4 | 6.5 | 1.3 | 2.1 | 1.84 |
| John Lannan* |   | sp | 23 | 18 | 7 | 1 | 7 | 6 | 2 | 13 | 5 | 0 | 8.5 | 3.6 | 12.4 | 5.8 | 1.1 | 1.6 | 1.34 |
| Brandon League |   | mr | 25 | 0 | 0 | 2 | 3 | 2 | 0 | 1 | 0 | 0 | 7.6 | 4.1 | 12.5 | 6.3 | 0.5 | 1.5 | 1.30 |
| Wade LeBlanc* |   | sp | 23 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 12.2 | 6.3 | 18.6 | 5.9 | 3.0 | 0.9 | 2.06 |
| Wil Ledezma* |   | mr | 27 | 12 | 2 | 2 | 3 | 4 | 0 | 4 | 4 | 0 | 7.9 | 6.3 | 14.7 | 8.2 | 0.6 | 1.3 | 1.58 |
| Cliff Lee* | MID | sp | 29 | 3 | 0 | 1 | 5 | 4 | 0 | 2 | 3 | 0 | 8.6 | 1.4 | 10.2 | 6.9 | 0.5 | 5.0 | 1.11 |
| Jon Lester* | EDG | sp | 24 | 8 | 5 | 1 | 10 | 3 | 1 | 6 | 3 | 0 | 8.6 | 2.8 | 11.9 | 6.5 | 0.6 | 2.3 | 1.27 |
| Jensen Lewis |   | cl | 24 | 1 | 1 | 3 | 5 | 0 | 0 | 2 | 2 | 0 | 9.3 | 3.7 | 13.6 | 7.1 | 1.1 | 1.9 | 1.44 |
| Scott Lewis* |   | sp | 24 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 7.5 | 2.3 | 9.8 | 5.6 | 1.5 | 2.5 | 1.08 |
| Brad Lidge | Pal | cl | 31 | 8 | 1 | 4 | 1 | 5 | 0 | 2 | 1 | 0 | 6.5 | 4.5 | 11.2 | 11.9 | 0.3 | 2.6 | 1.23 |
| Jon Lieber |   | mr | 38 | 0 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 0 | 11.4 | 1.2 | 12.9 | 5.2 | 1.9 | 4.5 | 1.39 |
| Ted Lilly* | OTR | sp | 32 | 12 | 8 | 2 | 7 | 4 | 4 | 5 | 3 | 0 | 8.2 | 2.8 | 11.3 | 8.1 | 1.4 | 2.9 | 1.23 |
| Tim Lincecum | WIZ | sp | 24 | 20 | 3 | 1 | 6 | 17 | 2 | 11 | 3 | 0 | 7.2 | 3.3 | 10.8 | 10.5 | 0.4 | 3.2 | 1.17 |
| Mike Lincoln |   | mr | 33 | 1 | 1 | 1 | 3 | 3 | 0 | 3 | 3 | 0 | 8.4 | 3.1 | 11.9 | 7.3 | 1.3 | 2.4 | 1.28 |
| Matt Lindstrom |   | mr | 28 | 1 | 1 | 4 | 1 | 4 | 0 | 6 | 1 | 0 | 8.9 | 4.1 | 13.2 | 6.8 | 0.2 | 1.7 | 1.45 |
| Scott Linebrink | EDG | mr | 31 | 2 | 0 | 1 | 0 | 3 | 0 | 2 | 0 | 0 | 8.0 | 1.7 | 9.7 | 7.8 | 1.6 | 4.4 | 1.08 |
| Francisco Liriano* | ROK | sp | 24 | 6 | 3 | 1 | 1 | 3 | 0 | 2 | 3 | 0 | 8.8 | 3.8 | 12.7 | 7.9 | 0.8 | 2.1 | 1.39 |
| Jesse Litsch | EDG | sp | 23 | 3 | 6 | 2 | 8 | 4 | 0 | 1 | 4 | 0 | 9.1 | 2.0 | 11.5 | 5.1 | 1.0 | 2.5 | 1.23 |
| Wes Littleton |   | mr | 25 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 9.0 | 4.0 | 14.5 | 7.0 | 0.5 | 1.8 | 1.44 |
| Radhames Liz |   | sp | 25 | 12 | 2 | 3 | 3 | 6 | 0 | 1 | 3 | 0 | 10.6 | 5.4 | 16.3 | 6.1 | 1.7 | 1.1 | 1.78 |
| Esteban Loaiza |   | mr | 36 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 0 | 9.0 | 1.7 | 11.0 | 3.3 | 1.3 | 2.0 | 1.19 |
| Kameron Loe |   | mr | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 10.6 | 2.3 | 12.9 | 5.9 | 0.9 | 2.5 | 1.43 |
| Adam Loewen* |   | sp | 24 | 3 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 10.5 | 7.6 | 18.1 | 5.9 | 2.1 | 0.8 | 2.02 |
| Boone Logan* |   | mr | 23 | 3 | 1 | 3 | 1 | 1 | 0 | 2 | 0 | 0 | 12.1 | 3.0 | 15.3 | 8.9 | 1.5 | 3.0 | 1.68 |
| Kyle Lohse | CCL | sp | 29 | 9 | 3 | 3 | 3 | 5 | 0 | 6 | 4 | 0 | 9.5 | 2.2 | 11.8 | 5.4 | 0.8 | 2.4 | 1.30 |
| Braden Looper |   | sp | 33 | 1 | 0 | 1 | 11 | 3 | 1 | 7 | 5 | 0 | 9.8 | 2.0 | 12.3 | 4.9 | 1.1 | 2.4 | 1.31 |
| Aquilino Lopez |   | mr | 33 | 4 | 1 | 4 | 2 | 6 | 1 | 0 | 10 | 0 | 9.8 | 2.5 | 12.6 | 7.0 | 1.0 | 2.8 | 1.37 |
| Javier Lopez* | OTR | mr | 30 | 1 | 3 | 0 | 2 | 1 | 0 | 1 | 1 | 0 | 8.0 | 4.1 | 12.4 | 5.8 | 0.6 | 1.4 | 1.35 |
| Shane Loux |   | mr | 28 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 9.0 | 1.1 | 11.3 | 2.3 | 0.6 | 2.0 | 1.13 |
| Derek Lowe | BON | sp | 35 | 14 | 3 | 7 | 1 | 2 | 0 | 8 | 7 | 0 | 8.3 | 1.9 | 10.2 | 6.3 | 0.6 | 3.3 | 1.13 |
| Mark Lowe |   | mr | 25 | 5 | 0 | 0 | 4 | 2 | 0 | 3 | 3 | 0 | 11.0 | 4.8 | 16.4 | 7.8 | 0.8 | 1.6 | 1.76 |
| Devon Lowery |   | mr | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.5 | 4.2 | 16.6 | 12.5 | 4.2 | 3.0 | 1.85 |
| Brandon Lyon | Pal | cl | 28 | 1 | 1 | 1 | 0 | 1 | 0 | 2 | 1 | 0 | 11.4 | 2.0 | 13.3 | 6.7 | 1.1 | 3.4 | 1.48 |
| Mike MacDougal |   | mr | 31 | 1 | 0 | 2 | 2 | 4 | 1 | 0 | 0 | 0 | 8.5 | 6.4 | 15.9 | 6.4 | 0.0 | 1.0 | 1.65 |
| Greg Maddux | Pal | sp | 42 | 24 | 5 | 5 | 6 | 2 | 2 | 9 | 8 | 0 | 9.5 | 1.4 | 11.1 | 4.5 | 1.0 | 3.3 | 1.21 |
| Warner Madrigal |   | mr | 24 | 4 | 2 | 0 | 0 | 2 | 0 | 1 | 2 | 0 | 9.0 | 3.5 | 12.5 | 5.5 | 1.0 | 1.6 | 1.39 |
| Ryan Madson | CCL | mr | 27 | 7 | 1 | 4 | 1 | 2 | 1 | 3 | 2 | 0 | 8.6 | 2.5 | 11.2 | 7.3 | 0.7 | 2.9 | 1.23 |
| Ron Mahay* |   | mr | 37 | 2 | 2 | 0 | 1 | 1 | 0 | 0 | 6 | 0 | 8.5 | 4.0 | 12.7 | 6.8 | 0.8 | 1.7 | 1.39 |
| Paul Maholm* | MAD | sp | 26 | 5 | 7 | 2 | 9 | 2 | 1 | 8 | 8 | 0 | 8.8 | 2.7 | 11.9 | 6.1 | 0.9 | 2.2 | 1.28 |
| John Maine | BT | sp | 27 | 7 | 6 | 2 | 4 | 10 | 0 | 10 | 5 | 0 | 7.8 | 4.3 | 12.4 | 7.8 | 1.0 | 1.8 | 1.35 |
| Gary Majewski |   | mr | 28 | 1 | 0 | 0 | 3 | 1 | 0 | 2 | 4 | 0 | 13.7 | 3.4 | 17.8 | 6.1 | 1.3 | 1.8 | 1.90 |
| Charlie Manning* |   | mr | 29 | 4 | 0 | 2 | 0 | 2 | 0 | 2 | 0 | 0 | 7.5 | 6.6 | 14.1 | 7.9 | 1.7 | 1.2 | 1.57 |
| Shaun Marcum | COP | sp | 26 | 5 | 2 | 2 | 8 | 3 | 0 | 1 | 3 | 1 | 7.5 | 3.0 | 10.9 | 7.3 | 1.2 | 2.5 | 1.16 |
| Carlos Marmol | WIZ | mr | 25 | 3 | 1 | 3 | 6 | 6 | 1 | 2 | 3 | 0 | 4.1 | 4.2 | 9.0 | 11.7 | 1.0 | 2.8 | 0.93 |
| Jason Marquis | CCL | sp | 29 | 11 | 1 | 6 | 8 | 8 | 1 | 10 | 7 | 0 | 9.3 | 3.8 | 13.5 | 4.9 | 0.8 | 1.3 | 1.45 |
| Sean Marshall* | LON | mr | 25 | 5 | 2 | 4 | 4 | 3 | 0 | 4 | 3 | 0 | 8.3 | 3.2 | 12.0 | 8.0 | 1.2 | 2.5 | 1.27 |
| Damaso Marte* | WIZ | mr | 33 | 3 | 1 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 7.2 | 3.6 | 11.1 | 9.8 | 0.7 | 2.7 | 1.20 |
| Pedro Martinez |   | sp | 36 | 15 | 2 | 3 | 6 | 2 | 1 | 7 | 4 | 0 | 10.5 | 3.6 | 14.6 | 7.2 | 1.6 | 2.0 | 1.57 |
| Shairon Martis |   | sp | 21 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 7.8 | 5.2 | 13.1 | 10.0 | 2.2 | 1.9 | 1.45 |
| Nick Masset | GEO | mr | 26 | 2 | 1 | 4 | 2 | 3 | 1 | 3 | 1 | 0 | 10.3 | 3.8 | 14.4 | 6.2 | 1.0 | 1.7 | 1.56 |
| Justin Masterson | OTR | mr | 23 | 9 | 1 | 3 | 8 | 1 | 0 | 1 | 1 | 0 | 6.9 | 4.1 | 11.8 | 6.9 | 1.0 | 1.7 | 1.22 |
| Tom Mastny |   | mr | 27 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 12.6 | 4.9 | 17.5 | 8.6 | 2.7 | 1.7 | 1.95 |
| Doug Mathis |   | sp | 25 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 14.9 | 5.6 | 20.6 | 3.6 | 1.2 | 0.6 | 2.28 |
| Osiris Matos |   | mr | 23 | 2 | 1 | 1 | 1 | 0 | 0 | 1 | 3 | 0 | 11.3 | 3.9 | 15.7 | 7.0 | 1.3 | 1.8 | 1.69 |
| Daisuke Matsuzaka | OTR | sp | 27 | 15 | 5 | 1 | 7 | 5 | 0 | 3 | 4 | 0 | 6.9 | 5.0 | 12.3 | 8.3 | 0.6 | 1.6 | 1.32 |
| Brandon McCarthy | EDG | sp | 24 | 6 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 8.2 | 3.3 | 11.9 | 4.1 | 1.2 | 1.3 | 1.27 |
| Kyle McClellan | MAD | mr | 24 | 2 | 1 | 2 | 4 | 6 | 0 | 2 | 1 | 0 | 9.4 | 3.1 | 13.0 | 7.0 | 0.8 | 2.3 | 1.39 |
| Seth McClung | EDG | mr | 27 | 5 | 4 | 3 | 7 | 5 | 0 | 5 | 6 | 0 | 7.9 | 4.7 | 13.2 | 7.4 | 0.9 | 1.6 | 1.41 |
| Bob McCrory |   | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 14.2 | 11.4 | 25.6 | 7.1 | 0.0 | 0.6 | 2.84 |
| James McDonald |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 7.5 | 1.5 | 9.0 | 3.0 | 0.0 | 2.0 | 1.00 |
| Dustin McGowan |   | sp | 26 | 12 | 4 | 1 | 5 | 5 | 0 | 2 | 8 | 0 | 9.3 | 3.1 | 12.8 | 6.9 | 0.7 | 2.2 | 1.37 |
| Gil Meche | CRH | sp | 29 | 12 | 2 | 2 | 0 | 5 | 0 | 4 | 10 | 0 | 8.7 | 3.1 | 11.9 | 7.8 | 0.8 | 2.5 | 1.32 |
| Brandon Medders |   | mr | 28 | 5 | 1 | 2 | 2 | 1 | 0 | 1 | 2 | 0 | 7.8 | 5.0 | 13.7 | 3.7 | 0.9 | 0.7 | 1.42 |
| Evan Meek |   | mr | 25 | 2 | 0 | 2 | 1 | 3 | 0 | 1 | 1 | 0 | 7.6 | 8.3 | 16.6 | 4.8 | 2.1 | 0.6 | 1.77 |
| Jon Meloan |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 4.5 | 4.5 | 9.0 | 0.0 | 2.0 | 0.50 |
| Luis Mendoza |   | mr | 24 | 7 | 2 | 4 | 6 | 5 | 0 | 0 | 2 | 0 | 13.8 | 3.6 | 18.2 | 5.0 | 1.0 | 1.4 | 1.93 |
| Kent Mercker* |   | mr | 40 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 8.6 | 5.3 | 13.8 | 4.0 | 0.7 | 0.8 | 1.54 |
| Cla Meredith |   | mr | 25 | 12 | 1 | 3 | 1 | 2 | 0 | 2 | 3 | 0 | 10.1 | 3.1 | 13.3 | 6.3 | 0.8 | 2.0 | 1.46 |
| Randy Messenger |   | mr | 26 | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 11.4 | 3.6 | 15.6 | 5.0 | 0.7 | 1.4 | 1.66 |
| Dan Meyer* |   | mr | 26 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 11.4 | 4.6 | 16.3 | 6.5 | 2.0 | 1.4 | 1.77 |
| Kam Mickolio |   | mr | 24 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 0 | 9.4 | 4.7 | 14.1 | 9.4 | 0.0 | 2.0 | 1.57 |
| Jose Mijares* |   | mr | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.6 | 0.0 | 2.6 | 4.4 | 0.0 | 99.0 | 0.29 |
| Andrew Miller* | GEO | sp | 23 | 13 | 3 | 4 | 4 | 4 | 0 | 10 | 7 | 0 | 10.1 | 4.7 | 15.1 | 7.5 | 0.6 | 1.6 | 1.64 |
| Jim Miller |   | mr | 26 | 2 | 0 | 2 | 1 | 1 | 0 | 1 | 1 | 0 | 10.6 | 5.9 | 17.6 | 9.4 | 0.0 | 1.6 | 1.83 |
| Justin Miller |   | mr | 30 | 4 | 1 | 3 | 3 | 1 | 1 | 0 | 1 | 0 | 8.9 | 3.9 | 13.3 | 8.3 | 0.8 | 2.2 | 1.41 |
| Trever Miller* |   | mr | 35 | 0 | 2 | 1 | 4 | 1 | 0 | 1 | 1 | 0 | 8.1 | 4.2 | 13.1 | 9.1 | 0.4 | 2.2 | 1.36 |
| Kevin Millwood |   | sp | 33 | 26 | 4 | 3 | 6 | 2 | 1 | 5 | 2 | 0 | 11.7 | 2.6 | 14.7 | 6.7 | 1.0 | 2.6 | 1.59 |
| Zach Miner | GEO | mr | 26 | 8 | 4 | 3 | 6 | 4 | 0 | 4 | 3 | 0 | 9.0 | 3.5 | 13.0 | 4.7 | 0.8 | 1.3 | 1.39 |
| Pat Misch* |   | mr | 26 | 5 | 0 | 2 | 3 | 1 | 1 | 3 | 4 | 0 | 9.6 | 2.6 | 12.7 | 6.5 | 1.9 | 2.5 | 1.36 |
| Garrett Mock | CCL | mr | 25 | 2 | 0 | 3 | 0 | 3 | 1 | 1 | 1 | 0 | 8.1 | 5.0 | 13.2 | 10.1 | 0.9 | 2.0 | 1.46 |
| Brian Moehler |   | sp | 36 | 9 | 0 | 1 | 4 | 3 | 0 | 7 | 8 | 0 | 10.0 | 2.2 | 12.4 | 4.9 | 1.2 | 2.3 | 1.35 |
| Franklin Morales* |   | sp | 22 | 5 | 0 | 2 | 1 | 1 | 3 | 2 | 2 | 0 | 9.9 | 6.0 | 16.3 | 3.2 | 0.7 | 0.5 | 1.78 |
| Juan Morillo |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Matt Morris |   | sp | 33 | 3 | 3 | 1 | 2 | 2 | 0 | 2 | 2 | 0 | 16.5 | 2.8 | 20.1 | 3.6 | 2.4 | 1.3 | 2.15 |
| Brandon Morrow | CRH | mr | 23 | 3 | 1 | 1 | 0 | 5 | 0 | 1 | 0 | 0 | 5.6 | 4.7 | 10.3 | 10.4 | 1.4 | 2.2 | 1.14 |
| Charlie Morton | LON | sp | 24 | 7 | 2 | 2 | 2 | 2 | 0 | 5 | 4 | 0 | 9.6 | 4.9 | 14.8 | 5.8 | 1.1 | 1.2 | 1.62 |
| Dustin Moseley |   | sp | 26 | 4 | 2 | 0 | 2 | 3 | 1 | 1 | 3 | 0 | 12.5 | 3.6 | 16.5 | 6.6 | 1.1 | 1.9 | 1.79 |
| Guillermo Mota |   | mr | 34 | 4 | 1 | 0 | 0 | 4 | 1 | 1 | 3 | 0 | 8.2 | 4.4 | 12.6 | 7.9 | 1.1 | 1.8 | 1.40 |
| Jason Motte |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.1 | 2.5 | 6.5 | 13.1 | 0.0 | 5.3 | 0.73 |
| Jamie Moyer* | LON | sp | 45 | 13 | 6 | 4 | 11 | 3 | 0 | 7 | 2 | 0 | 9.1 | 2.8 | 12.5 | 5.6 | 0.9 | 2.0 | 1.33 |
| Peter Moylan |   | mr | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.9 | 1.6 | 11.1 | 7.9 | 1.6 | 5.0 | 1.06 |
| Edward Mujica |   | mr | 24 | 0 | 1 | 3 | 1 | 1 | 0 | 0 | 4 | 0 | 10.7 | 2.3 | 13.3 | 6.3 | 1.2 | 2.7 | 1.45 |
| Mark Mulder* |   | mr | 30 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 21.6 | 10.8 | 37.8 | 10.8 | 0.0 | 1.0 | 3.60 |
| Carlos Muniz |   | mr | 27 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 9.3 | 2.7 | 12.7 | 6.2 | 1.5 | 2.3 | 1.33 |
| A.J. Murray* |   | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.1 | 3.5 | 17.6 | 5.9 | 0.0 | 1.7 | 1.96 |
| Neal Musser* |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 9.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Mike Mussina | MID | sp | 39 | 12 | 7 | 3 | 8 | 4 | 0 | 4 | 7 | 0 | 9.6 | 1.4 | 11.4 | 6.7 | 0.8 | 4.8 | 1.22 |
| Brett Myers | CRH | sp | 27 | 17 | 3 | 6 | 6 | 2 | 0 | 4 | 3 | 0 | 9.3 | 3.1 | 12.7 | 7.7 | 1.4 | 2.5 | 1.38 |
| Joe Nathan | WIZ | cl | 33 | 5 | 0 | 4 | 2 | 2 | 0 | 1 | 0 | 0 | 5.7 | 2.4 | 8.4 | 9.8 | 0.7 | 4.1 | 0.90 |
| Joe Nelson | CCL | mr | 33 | 4 | 0 | 4 | 2 | 3 | 0 | 2 | 0 | 1 | 7.0 | 3.7 | 11.0 | 10.0 | 0.8 | 2.7 | 1.19 |
| Pat Neshek | BON | mr | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 8.1 | 2.7 | 10.8 | 10.1 | 1.3 | 3.8 | 1.20 |
| Josh Newman* |   | mr | 26 | 1 | 0 | 1 | 2 | 0 | 1 | 0 | 1 | 0 | 14.4 | 6.9 | 22.4 | 4.6 | 2.3 | 0.7 | 2.36 |
| Jeff Niemann |   | mr | 25 | 2 | 1 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 10.1 | 4.5 | 15.2 | 7.9 | 1.7 | 1.8 | 1.63 |
| Jonathon Niese* |   | sp | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 12.9 | 5.1 | 18.0 | 7.1 | 1.3 | 1.4 | 2.00 |
| Fernando Nieve |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.3 | 1.7 | 16.0 | 10.1 | 1.7 | 6.0 | 1.78 |
| Dustin Nippert |   | mr | 27 | 5 | 2 | 3 | 1 | 1 | 1 | 3 | 1 | 0 | 11.6 | 4.6 | 16.3 | 6.9 | 1.3 | 1.5 | 1.80 |
| Ricky Nolasco | CCL | sp | 25 | 7 | 5 | 6 | 6 | 1 | 3 | 6 | 9 | 0 | 8.1 | 1.8 | 10.2 | 7.9 | 1.2 | 4.4 | 1.10 |
| Hideo Nomo |   | mr | 39 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 20.8 | 8.3 | 29.1 | 6.2 | 6.2 | 0.8 | 3.23 |
| Leo Nunez | ROK | mr | 24 | 1 | 1 | 2 | 4 | 3 | 0 | 3 | 2 | 0 | 8.4 | 2.8 | 11.9 | 4.8 | 0.4 | 1.7 | 1.24 |
| Vladimir Nunez |   | mr | 33 | 2 | 2 | 5 | 1 | 2 | 0 | 0 | 3 | 0 | 8.8 | 5.2 | 14.3 | 6.6 | 0.0 | 1.3 | 1.56 |
| Mike O'Connor* |   | mr | 27 | 1 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 0 | 11.0 | 11.0 | 22.0 | 4.0 | 3.0 | 0.4 | 2.44 |
| Darren O'Day | MID | mr | 25 | 2 | 1 | 6 | 4 | 1 | 0 | 2 | 1 | 0 | 10.2 | 2.9 | 13.9 | 6.0 | 0.4 | 2.1 | 1.45 |
| Eric O'Flaherty* |   | mr | 23 | 3 | 1 | 2 | 2 | 0 | 0 | 0 | 1 | 0 | 21.6 | 5.4 | 29.7 | 5.4 | 2.7 | 1.0 | 3.00 |
| Ross Ohlendorf |   | mr | 25 | 2 | 1 | 3 | 1 | 10 | 1 | 1 | 1 | 0 | 12.4 | 4.5 | 16.9 | 7.0 | 1.4 | 1.6 | 1.87 |
| Will Ohman* | MAD | mr | 30 | 1 | 2 | 4 | 1 | 2 | 0 | 3 | 0 | 0 | 7.8 | 3.4 | 11.4 | 8.1 | 0.5 | 2.4 | 1.24 |
| Hideki Okajima* | COP | mr | 32 | 0 | 1 | 1 | 1 | 2 | 0 | 0 | 3 | 0 | 7.1 | 3.3 | 10.6 | 8.7 | 0.9 | 2.6 | 1.16 |
| Darren Oliver* | GEO | mr | 37 | 5 | 2 | 2 | 4 | 3 | 0 | 4 | 3 | 0 | 8.4 | 2.0 | 10.9 | 6.0 | 0.6 | 3.0 | 1.15 |
| Scott Olsen* |   | sp | 24 | 8 | 7 | 13 | 3 | 5 | 0 | 7 | 4 | 0 | 8.7 | 3.1 | 11.9 | 5.0 | 1.3 | 1.6 | 1.31 |
| Garrett Olson* |   | sp | 24 | 20 | 2 | 1 | 8 | 6 | 0 | 4 | 4 | 0 | 11.4 | 4.2 | 16.1 | 5.6 | 1.2 | 1.3 | 1.73 |
| Franquelis Osoria |   | mr | 26 | 0 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 0 | 12.9 | 1.8 | 15.3 | 4.6 | 1.5 | 2.6 | 1.63 |
| Roy Oswalt | BT | sp | 30 | 1 | 1 | 2 | 10 | 1 | 0 | 8 | 9 | 0 | 8.6 | 2.0 | 11.0 | 7.1 | 1.0 | 3.5 | 1.18 |
| Josh Outman* |   | sp | 23 | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 2 | 0 | 11.9 | 2.8 | 15.4 | 6.7 | 0.4 | 2.4 | 1.64 |
| Micah Owings | MUL | sp | 25 | 3 | 2 | 0 | 12 | 4 | 0 | 2 | 4 | 0 | 8.9 | 3.5 | 13.5 | 7.5 | 1.2 | 2.1 | 1.39 |
| Vicente Padilla |   | sp | 30 | 9 | 4 | 4 | 15 | 12 | 3 | 1 | 3 | 0 | 9.7 | 3.4 | 13.9 | 6.7 | 1.4 | 2.0 | 1.46 |
| Matt Palmer |   | sp | 29 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 0 | 12.1 | 9.2 | 22.7 | 2.1 | 0.7 | 0.2 | 2.37 |
| Jonathan Papelbon | BON | cl | 27 | 2 | 0 | 0 | 0 | 2 | 0 | 4 | 1 | 0 | 7.5 | 1.0 | 8.6 | 10.0 | 0.5 | 9.6 | 0.95 |
| Mike Parisi |   | mr | 25 | 0 | 1 | 2 | 0 | 3 | 0 | 3 | 1 | 0 | 14.5 | 5.9 | 20.3 | 5.1 | 0.8 | 0.9 | 2.26 |
| Chan Ho Park |   | mr | 35 | 5 | 1 | 7 | 4 | 2 | 1 | 4 | 0 | 0 | 9.2 | 3.4 | 12.9 | 7.5 | 1.1 | 2.2 | 1.40 |
| Bobby Parnell |   | mr | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.4 | 3.6 | 9.0 | 5.4 | 0.0 | 1.5 | 1.00 |
| Chad Paronto |   | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.6 | 1.7 | 11.3 | 3.5 | 1.7 | 2.0 | 1.26 |
| James Parr |   | sp | 22 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 11.7 | 3.6 | 15.3 | 5.6 | 1.6 | 1.6 | 1.70 |
| Manny Parra* |   | sp | 25 | 8 | 5 | 1 | 2 | 17 | 2 | 10 | 2 | 0 | 9.8 | 4.1 | 14.0 | 8.0 | 1.0 | 2.0 | 1.54 |
| John Parrish* |   | mr | 30 | 2 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 10.0 | 3.2 | 13.2 | 4.5 | 1.1 | 1.4 | 1.46 |
| Scott Patterson |   | mr | 29 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 3.9 | 11.6 | 15.4 | 13.5 | 0.0 | 1.2 | 1.71 |
| David Pauley |   | mr | 25 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 16.8 | 3.6 | 21.2 | 8.0 | 1.5 | 2.2 | 2.27 |
| Carl Pavano |   | sp | 32 | 5 | 1 | 0 | 4 | 0 | 1 | 3 | 3 | 0 | 10.7 | 2.6 | 14.4 | 3.9 | 1.3 | 1.5 | 1.49 |
| Jake Peavy | MUL | sp | 27 | 18 | 9 | 1 | 5 | 6 | 0 | 7 | 1 | 0 | 7.6 | 3.1 | 10.9 | 8.6 | 0.9 | 2.8 | 1.18 |
| Jailen Peguero |   | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 8.7 | 3.9 | 13.5 | 4.8 | 0.0 | 1.3 | 1.39 |
| Mike Pelfrey |   | sp | 24 | 5 | 6 | 1 | 13 | 2 | 0 | 11 | 5 | 0 | 9.4 | 2.9 | 12.8 | 4.9 | 0.5 | 1.7 | 1.36 |
| Tony Pena |   | mr | 26 | 2 | 0 | 5 | 3 | 4 | 0 | 4 | 4 | 0 | 9.9 | 2.1 | 12.4 | 6.4 | 0.6 | 3.1 | 1.33 |
| Brad Penny |   | sp | 30 | 8 | 3 | 0 | 3 | 1 | 1 | 10 | 2 | 1 | 10.6 | 4.0 | 14.9 | 4.8 | 1.2 | 1.2 | 1.63 |
| Joel Peralta | MID | mr | 32 | 3 | 1 | 0 | 2 | 1 | 0 | 1 | 3 | 0 | 9.6 | 2.4 | 12.3 | 6.5 | 2.6 | 2.7 | 1.33 |
| Troy Percival |   | cl | 38 | 7 | 2 | 0 | 1 | 2 | 0 | 1 | 2 | 0 | 5.7 | 5.3 | 11.2 | 7.5 | 1.8 | 1.4 | 1.23 |
| Chris Perez | LON | mr | 22 | 3 | 1 | 0 | 1 | 2 | 0 | 1 | 3 | 0 | 7.3 | 4.8 | 12.3 | 9.1 | 1.1 | 1.9 | 1.34 |
| Odalis Perez* |   | sp | 31 | 13 | 7 | 4 | 8 | 5 | 2 | 12 | 1 | 0 | 10.3 | 3.1 | 13.8 | 6.7 | 1.2 | 2.2 | 1.48 |
| Oliver Perez* | WIZ | sp | 26 | 8 | 1 | 4 | 11 | 9 | 1 | 9 | 7 | 0 | 7.7 | 4.9 | 13.1 | 8.4 | 1.1 | 1.7 | 1.40 |
| Rafael Perez* | BT | mr | 26 | 2 | 3 | 3 | 2 | 3 | 0 | 2 | 0 | 0 | 7.9 | 2.7 | 10.8 | 10.1 | 0.9 | 3.7 | 1.18 |
| Glen Perkins* | BON | sp | 25 | 3 | 4 | 0 | 3 | 2 | 1 | 7 | 4 | 0 | 10.9 | 2.3 | 13.4 | 4.4 | 1.5 | 1.9 | 1.47 |
| Yusmeiro Petit | WIZ | mr | 23 | 2 | 1 | 2 | 1 | 3 | 1 | 4 | 2 | 0 | 7.2 | 2.2 | 9.6 | 6.7 | 1.9 | 3.0 | 1.05 |
| Andy Pettitte* |   | sp | 36 | 20 | 8 | 4 | 7 | 6 | 1 | 8 | 7 | 0 | 10.3 | 2.4 | 13.0 | 7.0 | 0.8 | 2.9 | 1.41 |
| Adam Pettyjohn* |   | mr | 31 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 24.8 | 4.5 | 31.5 | 2.3 | 4.5 | 0.5 | 3.25 |
| Carmen Pignatiello* |   | mr | 25 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 27.0 | 27.0 | 67.5 | 0.0 | 0.0 | 0.0 | 6.00 |
| Joel Pineiro | CCL | sp | 29 | 5 | 4 | 0 | 2 | 1 | 0 | 7 | 3 | 0 | 10.9 | 2.1 | 13.1 | 4.9 | 1.3 | 2.3 | 1.45 |
| Renyel Pinto* |   | mr | 25 | 1 | 1 | 2 | 4 | 8 | 0 | 6 | 5 | 0 | 7.2 | 5.4 | 13.2 | 7.8 | 1.3 | 1.4 | 1.41 |
| Sidney Ponson |   | sp | 31 | 3 | 5 | 2 | 7 | 4 | 0 | 2 | 8 | 0 | 11.3 | 3.2 | 14.9 | 3.8 | 0.9 | 1.2 | 1.61 |
| David Price* |   | mr | 22 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.8 | 2.6 | 9.0 | 7.7 | 0.6 | 3.0 | 0.93 |
| Scott Proctor |   | mr | 31 | 1 | 1 | 1 | 0 | 6 | 0 | 1 | 2 | 0 | 9.5 | 5.6 | 15.1 | 10.7 | 1.6 | 1.9 | 1.68 |
| David Purcey* |   | sp | 26 | 2 | 3 | 0 | 4 | 3 | 0 | 2 | 3 | 0 | 9.3 | 4.0 | 13.8 | 8.0 | 1.2 | 2.0 | 1.48 |
| J.J. Putz | MID | cl | 31 | 1 | 2 | 2 | 2 | 2 | 0 | 0 | 1 | 0 | 8.9 | 5.4 | 14.8 | 10.9 | 0.8 | 2.0 | 1.60 |
| Chad Qualls | BON | mr | 29 | 3 | 0 | 2 | 3 | 6 | 0 | 4 | 3 | 0 | 7.5 | 2.2 | 10.0 | 8.7 | 0.5 | 3.9 | 1.07 |
| Edwar Ramirez | EDG | mr | 27 | 2 | 4 | 2 | 3 | 3 | 0 | 0 | 1 | 0 | 7.2 | 3.9 | 11.5 | 10.2 | 1.1 | 2.6 | 1.23 |
| Elizardo Ramirez |   | mr | 25 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 27.0 | 6.8 | 37.1 | 3.4 | 3.4 | 0.5 | 3.75 |
| Horacio Ramirez* |   | mr | 28 | 5 | 0 | 1 | 2 | 2 | 0 | 3 | 1 | 0 | 10.8 | 2.2 | 13.5 | 3.1 | 0.2 | 1.4 | 1.45 |
| Ramon Ramirez | LON | mr | 26 | 3 | 1 | 6 | 0 | 6 | 1 | 4 | 3 | 0 | 7.2 | 3.9 | 11.1 | 8.8 | 0.3 | 2.3 | 1.23 |
| Ramon Ramirez |   | sp | 25 | 2 | 3 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 5.7 | 3.7 | 9.7 | 7.0 | 1.0 | 1.9 | 1.04 |
| Clay Rapada* |   | mr | 27 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 8.0 | 5.9 | 14.3 | 6.3 | 0.0 | 1.1 | 1.55 |
| Darrell Rasner |   | sp | 27 | 3 | 3 | 1 | 5 | 4 | 0 | 5 | 3 | 1 | 10.7 | 3.1 | 14.2 | 5.3 | 1.1 | 1.7 | 1.54 |
| Jon Rauch |   | mr | 29 | 3 | 1 | 2 | 0 | 1 | 0 | 6 | 3 | 0 | 8.7 | 2.0 | 10.7 | 8.3 | 1.4 | 4.1 | 1.19 |
| Tim Redding |   | sp | 30 | 13 | 7 | 5 | 7 | 10 | 0 | 5 | 5 | 0 | 9.6 | 3.2 | 13.2 | 5.9 | 1.3 | 1.8 | 1.43 |
| Mark Redman* |   | sp | 34 | 2 | 0 | 2 | 1 | 1 | 0 | 5 | 1 | 0 | 12.1 | 3.2 | 15.5 | 4.0 | 1.4 | 1.3 | 1.70 |
| Steven Register |   | mr | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 11.7 | 5.4 | 17.1 | 7.2 | 3.6 | 1.3 | 1.90 |
| Chad Reineke |   | sp | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 7.0 | 6.0 | 13.0 | 6.5 | 0.5 | 1.1 | 1.44 |
| Chris Resop |   | mr | 25 | 1 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 0 | 7.9 | 4.9 | 13.7 | 6.4 | 1.0 | 1.3 | 1.42 |
| Al Reyes |   | mr | 38 | 2 | 0 | 2 | 1 | 1 | 0 | 0 | 2 | 0 | 8.3 | 4.0 | 12.7 | 7.5 | 0.8 | 1.9 | 1.37 |
| Anthony Reyes |   | sp | 26 | 3 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 8.6 | 2.8 | 11.6 | 4.6 | 0.7 | 1.7 | 1.27 |
| Dennys Reyes* |   | mr | 31 | 6 | 2 | 2 | 2 | 5 | 0 | 1 | 0 | 0 | 7.8 | 2.9 | 11.1 | 7.6 | 0.8 | 2.6 | 1.19 |
| Jo-Jo Reyes* |   | sp | 23 | 9 | 4 | 4 | 3 | 2 | 0 | 9 | 3 | 0 | 10.7 | 4.1 | 15.1 | 6.2 | 1.4 | 1.5 | 1.65 |
| Greg Reynolds |   | sp | 22 | 3 | 0 | 3 | 4 | 2 | 0 | 4 | 2 | 0 | 12.0 | 3.8 | 16.4 | 3.2 | 2.0 | 0.8 | 1.76 |
| Arthur Rhodes* | OTR | mr | 38 | 1 | 0 | 4 | 0 | 1 | 0 | 4 | 1 | 0 | 7.1 | 4.1 | 11.2 | 10.2 | 0.0 | 2.5 | 1.25 |
| Clayton Richard* |   | sp | 24 | 6 | 0 | 2 | 0 | 1 | 1 | 0 | 1 | 0 | 11.5 | 2.5 | 14.0 | 5.5 | 0.9 | 2.2 | 1.55 |
| Scott Richmond |   | sp | 28 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 10.7 | 0.7 | 12.0 | 6.7 | 0.7 | 10.0 | 1.26 |
| Jeff Ridgway* |   | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.5 | 0.9 | 8.4 | 7.4 | 2.8 | 8.0 | 0.83 |
| Juan Rincon |   | mr | 29 | 6 | 1 | 2 | 3 | 5 | 0 | 2 | 0 | 0 | 10.9 | 3.9 | 15.3 | 6.3 | 1.3 | 1.6 | 1.64 |
| Ricardo Rincon* |   | mr | 38 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 2.3 | 11.3 | 6.8 | 2.3 | 3.0 | 1.25 |
| Royce Ring* |   | mr | 27 | 3 | 0 | 3 | 2 | 0 | 1 | 3 | 2 | 0 | 12.9 | 4.0 | 17.7 | 6.4 | 0.8 | 1.6 | 1.88 |
| David Riske |   | mr | 31 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 4 | 0 | 10.0 | 5.3 | 15.3 | 5.7 | 1.3 | 1.1 | 1.70 |
| Mariano Rivera | ROK | cl | 38 | 6 | 1 | 0 | 2 | 1 | 0 | 1 | 1 | 0 | 5.2 | 0.8 | 6.2 | 9.8 | 0.5 | 12.8 | 0.67 |
| Saul Rivera |   | mr | 30 | 13 | 0 | 2 | 2 | 4 | 1 | 3 | 6 | 0 | 9.6 | 3.8 | 13.6 | 7.0 | 0.3 | 1.9 | 1.49 |
| Connor Robertson |   | mr | 26 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 10.3 | 2.6 | 14.1 | 2.6 | 1.3 | 1.0 | 1.43 |
| David Robertson |   | mr | 23 | 4 | 3 | 2 | 0 | 6 | 0 | 0 | 3 | 0 | 8.6 | 4.5 | 13.1 | 10.7 | 0.9 | 2.4 | 1.45 |
| Nate Robertson* |   | sp | 30 | 7 | 4 | 7 | 2 | 5 | 0 | 4 | 0 | 0 | 11.6 | 3.3 | 15.0 | 5.8 | 1.4 | 1.7 | 1.66 |
| Fernando Rodney | OTR | cl | 31 | 4 | 0 | 5 | 3 | 3 | 0 | 1 | 2 | 0 | 7.6 | 6.7 | 15.0 | 10.9 | 0.7 | 1.6 | 1.59 |
| Francisco Rodriguez | BON | cl | 26 | 8 | 0 | 4 | 2 | 6 | 0 | 1 | 1 | 0 | 7.1 | 4.5 | 11.9 | 10.1 | 0.5 | 2.3 | 1.29 |
| Wandy Rodriguez* | BT | sp | 29 | 4 | 3 | 3 | 5 | 2 | 3 | 2 | 5 | 0 | 8.9 | 2.9 | 12.1 | 8.6 | 0.9 | 3.0 | 1.31 |
| Josh Roenicke |   | mr | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 18.0 | 6.0 | 27.0 | 18.0 | 0.0 | 3.0 | 2.67 |
| Kenny Rogers* |   | sp | 43 | 1 | 2 | 3 | 9 | 4 | 1 | 7 | 10 | 0 | 11.0 | 3.7 | 15.1 | 4.2 | 1.1 | 1.2 | 1.63 |
| J.C. Romero* |   | mr | 32 | 10 | 2 | 5 | 5 | 2 | 1 | 4 | 0 | 0 | 6.3 | 5.8 | 12.8 | 7.9 | 0.8 | 1.4 | 1.34 |
| Sergio Romo |   | mr | 25 | 4 | 1 | 1 | 3 | 0 | 0 | 2 | 1 | 0 | 4.2 | 2.1 | 7.1 | 8.7 | 0.8 | 4.1 | 0.71 |
| Carlos Rosa |   | mr | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.1 | 0.0 | 8.1 | 8.1 | 0.0 | 99.0 | 0.90 |
| Leo Rosales |   | mr | 27 | 2 | 0 | 3 | 1 | 2 | 0 | 1 | 1 | 0 | 9.6 | 4.5 | 14.4 | 5.4 | 0.6 | 1.2 | 1.57 |
| Ryan Rowland-Smith* | CRH | mr | 25 | 4 | 2 | 0 | 2 | 2 | 1 | 2 | 3 | 0 | 8.7 | 3.7 | 12.5 | 5.9 | 1.0 | 1.6 | 1.37 |
| Rich Rundles* |   | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 5.4 | 14.4 | 10.8 | 0.0 | 2.0 | 1.60 |
| Josh Rupe |   | mr | 25 | 0 | 1 | 3 | 10 | 3 | 0 | 2 | 7 | 0 | 9.4 | 4.6 | 15.0 | 5.3 | 0.8 | 1.2 | 1.56 |
| Glendon Rusch* |   | mr | 33 | 3 | 0 | 7 | 0 | 2 | 0 | 5 | 5 | 0 | 10.1 | 2.7 | 12.8 | 5.9 | 1.1 | 2.2 | 1.42 |
| Adam Russell |   | mr | 25 | 0 | 0 | 1 | 2 | 3 | 0 | 2 | 1 | 0 | 10.4 | 3.5 | 14.5 | 7.6 | 0.3 | 2.2 | 1.54 |
| B.J. Ryan* | CRH | cl | 32 | 4 | 0 | 3 | 4 | 2 | 1 | 2 | 1 | 1 | 7.1 | 4.3 | 12.1 | 9.0 | 0.6 | 2.1 | 1.28 |
| Jae Kuk Ryu |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 6.8 | 6.8 | 6.8 | 0.0 | 1.0 | 0.75 |
| Kirk Saarloos |   | mr | 29 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 12.6 | 1.4 | 14.0 | 4.1 | 0.7 | 3.0 | 1.56 |
| C.C. Sabathia* | CRH | sp | 27 | 12 | 3 | 1 | 7 | 2 | 2 | 9 | 6 | 0 | 7.9 | 2.1 | 10.3 | 8.9 | 0.7 | 4.3 | 1.11 |
| Billy Sadler |   | mr | 26 | 3 | 3 | 4 | 8 | 8 | 0 | 2 | 2 | 0 | 6.9 | 5.5 | 14.0 | 8.5 | 1.2 | 1.6 | 1.38 |
| Takashi Saito | Pal | cl | 38 | 1 | 1 | 3 | 2 | 1 | 0 | 0 | 2 | 0 | 7.7 | 3.1 | 11.1 | 11.5 | 0.2 | 3.8 | 1.19 |
| Juan Salas |   | mr | 29 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.1 | 5.7 | 12.8 | 11.4 | 0.0 | 2.0 | 1.42 |
| Marino Salas |   | mr | 26 | 0 | 0 | 3 | 2 | 4 | 0 | 1 | 1 | 0 | 13.2 | 7.4 | 21.7 | 4.8 | 2.1 | 0.6 | 2.29 |
| Jeff Samardzija |   | mr | 23 | 5 | 1 | 2 | 1 | 2 | 0 | 1 | 1 | 0 | 7.8 | 4.9 | 13.0 | 8.1 | 0.0 | 1.7 | 1.41 |
| Chris Sampson | MUL | mr | 30 | 2 | 2 | 5 | 3 | 0 | 0 | 3 | 5 | 0 | 9.1 | 1.8 | 11.0 | 4.7 | 0.6 | 2.7 | 1.20 |
| Brian Sanches |   | mr | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 13.1 | 4.1 | 18.0 | 8.2 | 1.6 | 2.0 | 1.91 |
| Anibal Sanchez | MAD | sp | 24 | 7 | 0 | 2 | 6 | 1 | 0 | 4 | 2 | 0 | 9.4 | 4.7 | 15.2 | 8.7 | 1.2 | 1.9 | 1.57 |
| Duaner Sanchez | BT | mr | 28 | 4 | 0 | 3 | 3 | 2 | 0 | 0 | 1 | 0 | 8.3 | 3.5 | 12.3 | 6.8 | 0.9 | 1.9 | 1.32 |
| Humberto Sanchez |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 9.0 | 13.5 | 4.5 | 0.0 | 0.5 | 1.50 |
| Jonathan Sanchez* | MAD | sp | 25 | 19 | 3 | 1 | 7 | 7 | 0 | 9 | 5 | 0 | 8.8 | 4.3 | 13.4 | 8.9 | 0.8 | 2.1 | 1.45 |
| Romulo Sanchez |   | mr | 24 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 2 | 0 | 9.4 | 4.0 | 14.2 | 2.0 | 0.0 | 0.5 | 1.50 |
| Ervin Santana | BON | sp | 25 | 16 | 4 | 2 | 8 | 5 | 1 | 3 | 5 | 0 | 8.1 | 1.9 | 10.4 | 8.8 | 0.9 | 4.6 | 1.12 |
| Johan Santana* | ROK | sp | 29 | 6 | 5 | 5 | 4 | 9 | 2 | 9 | 1 | 0 | 7.9 | 2.4 | 10.5 | 7.9 | 0.9 | 3.3 | 1.15 |
| Dennis Sarfate |   | mr | 27 | 6 | 2 | 2 | 7 | 6 | 1 | 2 | 3 | 0 | 7.0 | 7.0 | 14.8 | 9.7 | 0.9 | 1.4 | 1.56 |
| Joe Saunders* | MID | sp | 27 | 18 | 7 | 2 | 6 | 3 | 0 | 5 | 2 | 1 | 8.5 | 2.4 | 11.2 | 4.7 | 1.0 | 1.9 | 1.21 |
| Max Scherzer | LON | mr | 23 | 0 | 1 | 1 | 5 | 2 | 0 | 4 | 2 | 0 | 7.7 | 3.4 | 11.9 | 10.6 | 0.8 | 3.1 | 1.23 |
| Scott Schoeneweis* |   | mr | 34 | 2 | 2 | 6 | 4 | 3 | 0 | 2 | 2 | 0 | 8.7 | 3.7 | 13.0 | 5.4 | 1.1 | 1.5 | 1.38 |
| Chris Schroder |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 10.8 | 10.8 | 21.6 | 5.4 | 3.6 | 0.5 | 2.40 |
| Rudy Seanez | TON | mr | 39 | 7 | 1 | 4 | 1 | 2 | 0 | 2 | 2 | 0 | 7.9 | 5.2 | 13.3 | 6.2 | 0.4 | 1.2 | 1.45 |
| Bobby Seay* |   | mr | 30 | 2 | 1 | 7 | 2 | 3 | 0 | 3 | 4 | 0 | 9.4 | 4.0 | 13.7 | 9.3 | 0.6 | 2.3 | 1.49 |
| Alex Serrano |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 9.0 | 0.0 | 99.0 | 1.00 |
| Ben Sheets | CRH | sp | 29 | 13 | 7 | 2 | 1 | 8 | 0 | 6 | 7 | 0 | 8.2 | 2.1 | 10.4 | 7.2 | 0.8 | 3.4 | 1.15 |
| Steven Shell | CRH | mr | 25 | 2 | 1 | 1 | 2 | 1 | 0 | 1 | 1 | 0 | 6.1 | 3.6 | 10.1 | 7.4 | 0.9 | 2.0 | 1.08 |
| George Sherrill* | ROK | cl | 31 | 3 | 0 | 6 | 1 | 1 | 0 | 1 | 3 | 0 | 7.9 | 5.6 | 13.7 | 9.8 | 1.0 | 1.8 | 1.50 |
| James Shields | BON | sp | 26 | 7 | 6 | 0 | 12 | 6 | 0 | 6 | 0 | 0 | 8.7 | 1.7 | 10.9 | 6.7 | 1.0 | 4.0 | 1.15 |
| Scot Shields | ROK | mr | 32 | 8 | 1 | 2 | 2 | 2 | 0 | 1 | 1 | 0 | 8.0 | 4.1 | 12.4 | 9.1 | 0.9 | 2.2 | 1.34 |
| Brian Shouse* | OTR | mr | 39 | 1 | 1 | 4 | 0 | 1 | 0 | 4 | 1 | 0 | 8.1 | 2.5 | 10.5 | 5.8 | 0.9 | 2.4 | 1.17 |
| Carlos Silva |   | sp | 29 | 8 | 2 | 2 | 4 | 1 | 0 | 3 | 7 | 0 | 12.5 | 1.9 | 14.6 | 4.0 | 1.2 | 2.2 | 1.60 |
| Alfredo Simon |   | mr | 27 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 11.1 | 1.4 | 13.8 | 5.5 | 2.8 | 4.0 | 1.38 |
| Doug Slaten* |   | mr | 28 | 0 | 0 | 1 | 4 | 0 | 0 | 1 | 1 | 0 | 9.2 | 3.9 | 14.2 | 5.6 | 1.1 | 1.4 | 1.45 |
| Brian Slocum |   | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 36.0 | 0.0 | 40.5 | 4.5 | 9.0 | 99.0 | 4.00 |
| Kevin Slowey |   | sp | 24 | 4 | 4 | 1 | 4 | 1 | 0 | 1 | 5 | 0 | 9.0 | 1.3 | 10.6 | 6.9 | 1.2 | 5.1 | 1.15 |
| Chris Smith |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 8.8 | 3.4 | 12.3 | 6.4 | 2.9 | 1.9 | 1.36 |
| Greg Smith* |   | sp | 24 | 11 | 12 | 5 | 3 | 5 | 1 | 5 | 10 | 0 | 8.0 | 4.1 | 12.2 | 5.2 | 1.0 | 1.3 | 1.35 |
| Joe Smith | MAD | mr | 24 | 6 | 2 | 4 | 4 | 1 | 0 | 4 | 0 | 0 | 7.2 | 4.4 | 12.2 | 7.4 | 0.6 | 1.7 | 1.29 |
| John Smoltz |   | sp | 41 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 8.0 | 2.6 | 10.6 | 11.6 | 0.6 | 4.5 | 1.18 |
| Ian Snell |   | sp | 26 | 20 | 4 | 0 | 2 | 8 | 1 | 7 | 6 | 0 | 11.0 | 4.9 | 16.0 | 7.4 | 1.0 | 1.5 | 1.76 |
| Kyle Snyder |   | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 10.8 | 10.8 | 21.6 | 5.4 | 5.4 | 0.5 | 2.40 |
| Andy Sonnanstine | EDG | sp | 25 | 1 | 3 | 2 | 5 | 6 | 0 | 4 | 9 | 0 | 9.9 | 1.7 | 11.8 | 5.8 | 1.0 | 3.4 | 1.29 |
| Joakim Soria | BON | cl | 24 | 2 | 1 | 1 | 6 | 1 | 1 | 2 | 2 | 0 | 5.2 | 2.5 | 8.6 | 8.8 | 0.7 | 3.5 | 0.86 |
| Rafael Soriano | GEO | mr | 28 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 4.5 | 5.8 | 10.9 | 10.3 | 0.6 | 1.8 | 1.14 |
| Jorge Sosa |   | mr | 31 | 0 | 1 | 4 | 0 | 2 | 0 | 3 | 0 | 0 | 12.5 | 4.6 | 17.0 | 5.0 | 1.7 | 1.1 | 1.89 |
| Jeremy Sowers* |   | sp | 25 | 9 | 6 | 1 | 3 | 3 | 1 | 3 | 4 | 0 | 10.5 | 2.9 | 13.6 | 4.8 | 1.3 | 1.6 | 1.49 |
| Justin Speier |   | mr | 34 | 7 | 1 | 5 | 6 | 8 | 0 | 4 | 4 | 0 | 9.1 | 3.6 | 13.5 | 7.4 | 2.0 | 2.1 | 1.41 |
| Ryan Speier | MUL | mr | 28 | 6 | 2 | 2 | 4 | 2 | 0 | 1 | 3 | 0 | 9.2 | 3.2 | 13.1 | 5.8 | 0.5 | 1.8 | 1.37 |
| Levale Speigner |   | mr | 27 | 0 | 2 | 1 | 2 | 0 | 0 | 1 | 0 | 1 | 14.6 | 6.8 | 23.6 | 1.1 | 1.1 | 0.2 | 2.38 |
| Russ Springer | WIZ | mr | 39 | 1 | 2 | 0 | 1 | 2 | 0 | 2 | 0 | 0 | 7.0 | 3.2 | 10.4 | 8.0 | 0.7 | 2.5 | 1.13 |
| Mitch Stetter* |   | mr | 27 | 2 | 2 | 1 | 4 | 1 | 0 | 1 | 0 | 0 | 5.0 | 6.8 | 13.1 | 11.0 | 0.7 | 1.6 | 1.30 |
| Phil Stockman |   | mr | 28 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.5 | 4.9 | 8.6 | 11.0 | 0.0 | 2.3 | 0.82 |
| Brian Stokes |   | mr | 28 | 3 | 0 | 3 | 0 | 1 | 0 | 2 | 3 | 0 | 9.4 | 2.2 | 11.6 | 7.0 | 1.3 | 3.3 | 1.29 |
| Huston Street | GEO | cl | 24 | 6 | 3 | 6 | 1 | 2 | 0 | 3 | 3 | 0 | 7.5 | 3.5 | 11.1 | 8.9 | 0.8 | 2.6 | 1.21 |
| Eric Stults* |   | sp | 28 | 2 | 1 | 2 | 1 | 0 | 0 | 2 | 0 | 0 | 8.8 | 3.0 | 12.1 | 7.0 | 1.4 | 2.3 | 1.32 |
| Tanyon Sturtze |   | mr | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 3.9 | 7.7 | 3.9 | 0.0 | 1.0 | 0.86 |
| Jeff Suppan |   | sp | 33 | 4 | 7 | 7 | 4 | 3 | 1 | 10 | 4 | 0 | 10.5 | 3.4 | 14.1 | 4.6 | 1.5 | 1.3 | 1.54 |
| R.J. Swindle* |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 17.4 | 3.9 | 21.2 | 7.7 | 3.9 | 2.0 | 2.36 |
| Mitch Talbot |   | mr | 24 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 14.9 | 10.2 | 26.1 | 4.7 | 2.8 | 0.5 | 2.79 |
| Brian Tallet* | EDG | mr | 30 | 6 | 1 | 3 | 1 | 0 | 0 | 1 | 2 | 0 | 8.3 | 3.5 | 12.0 | 7.5 | 0.6 | 2.1 | 1.31 |
| Taylor Tankersley* |   | mr | 25 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 11.2 | 4.1 | 15.8 | 6.6 | 3.1 | 1.6 | 1.70 |
| Jack Taschner* |   | mr | 30 | 6 | 2 | 2 | 2 | 5 | 0 | 3 | 3 | 0 | 10.7 | 4.5 | 15.6 | 7.3 | 0.9 | 1.6 | 1.69 |
| Ty Taubenheim |   | sp | 25 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 10.5 | 4.5 | 15.0 | 6.0 | 0.0 | 1.3 | 1.67 |
| Julian Tavarez |   | mr | 35 | 5 | 0 | 4 | 3 | 2 | 1 | 5 | 2 | 0 | 12.0 | 4.6 | 17.1 | 8.4 | 0.8 | 1.8 | 1.85 |
| Robinson Tejeda | OTR | mr | 26 | 6 | 1 | 0 | 1 | 5 | 0 | 0 | 3 | 0 | 5.4 | 4.8 | 10.3 | 8.9 | 0.8 | 1.9 | 1.13 |
| Joe Thatcher* |   | mr | 26 | 1 | 0 | 2 | 0 | 0 | 0 | 2 | 3 | 0 | 14.7 | 4.6 | 19.3 | 6.0 | 1.4 | 1.3 | 2.14 |
| Justin Thomas* |   | mr | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 20.3 | 4.5 | 24.8 | 4.5 | 0.0 | 1.0 | 2.75 |
| Brad Thompson |   | mr | 26 | 1 | 1 | 1 | 3 | 2 | 0 | 2 | 3 | 0 | 10.0 | 2.6 | 13.1 | 4.5 | 0.7 | 1.7 | 1.41 |
| Daryl Thompson |   | sp | 22 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 12.6 | 4.4 | 17.6 | 3.8 | 1.9 | 0.9 | 1.88 |
| Rich Thompson |   | mr | 23 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 18.0 | 9.0 | 27.0 | 4.5 | 0.0 | 0.5 | 3.00 |
| Matt Thornton* | CRH | mr | 31 | 4 | 0 | 2 | 2 | 3 | 0 | 1 | 1 | 0 | 6.4 | 2.5 | 9.2 | 10.3 | 0.7 | 4.1 | 1.00 |
| Erick Threets* |   | mr | 26 | 1 | 0 | 2 | 3 | 1 | 0 | 1 | 0 | 0 | 9.9 | 8.1 | 20.7 | 5.4 | 0.9 | 0.7 | 2.00 |
| Mike Timlin |   | mr | 42 | 6 | 0 | 4 | 1 | 1 | 0 | 4 | 3 | 0 | 10.9 | 3.6 | 14.8 | 5.8 | 1.6 | 1.6 | 1.62 |
| Brett Tomko |   | sp | 35 | 3 | 0 | 2 | 0 | 4 | 0 | 1 | 2 | 0 | 10.7 | 2.3 | 13.0 | 6.3 | 1.4 | 2.7 | 1.44 |
| Salomon Torres | MUL | cl | 36 | 1 | 2 | 5 | 4 | 2 | 0 | 7 | 4 | 0 | 8.4 | 3.7 | 12.6 | 5.7 | 0.7 | 1.5 | 1.35 |
| Billy Traber* |   | mr | 28 | 3 | 1 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 12.4 | 3.8 | 17.3 | 5.9 | 1.6 | 1.6 | 1.80 |
| Steve Trachsel |   | sp | 37 | 6 | 3 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 12.0 | 6.1 | 18.4 | 3.6 | 2.3 | 0.6 | 2.02 |
| Ramon Troncoso |   | mr | 25 | 5 | 0 | 1 | 3 | 2 | 0 | 4 | 3 | 0 | 8.8 | 2.8 | 12.3 | 9.0 | 0.5 | 3.2 | 1.29 |
| Ryan Tucker |   | mr | 21 | 2 | 1 | 1 | 2 | 1 | 0 | 1 | 1 | 0 | 11.2 | 5.6 | 17.3 | 6.8 | 1.9 | 1.2 | 1.86 |
| Derrick Turnbow |   | mr | 30 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 17.1 | 18.5 | 36.9 | 7.1 | 1.4 | 0.4 | 3.95 |
| Merkin Valdez |   | mr | 26 | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 0 | 0 | 7.9 | 3.9 | 12.9 | 7.3 | 0.6 | 1.9 | 1.31 |
| Jose Valverde | WIZ | cl | 28 | 8 | 0 | 6 | 2 | 3 | 2 | 0 | 2 | 0 | 7.8 | 2.9 | 10.9 | 10.4 | 1.3 | 3.6 | 1.18 |
| John Van Benschoten |   | sp | 28 | 4 | 1 | 1 | 3 | 0 | 1 | 1 | 0 | 0 | 14.9 | 8.1 | 24.2 | 8.5 | 2.8 | 1.0 | 2.55 |
| Rick VandenHurk |   | sp | 23 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 12.9 | 6.4 | 20.6 | 12.9 | 0.6 | 2.0 | 2.14 |
| Claudio Vargas |   | mr | 30 | 2 | 1 | 0 | 2 | 1 | 0 | 1 | 1 | 0 | 8.0 | 2.7 | 11.2 | 4.9 | 1.0 | 1.8 | 1.19 |
| Javier Vazquez | Pal | sp | 31 | 9 | 3 | 2 | 6 | 2 | 0 | 4 | 4 | 0 | 9.2 | 2.6 | 12.1 | 8.6 | 1.1 | 3.3 | 1.32 |
| Jose Veras |   | mr | 27 | 5 | 3 | 6 | 3 | 4 | 0 | 2 | 1 | 0 | 8.1 | 4.5 | 13.1 | 9.8 | 1.1 | 2.2 | 1.40 |
| Justin Verlander | COP | sp | 25 | 8 | 9 | 8 | 14 | 6 | 3 | 4 | 6 | 0 | 8.7 | 3.9 | 13.3 | 7.3 | 0.8 | 1.9 | 1.40 |
| Carlos Villanueva |   | mr | 24 | 5 | 2 | 1 | 3 | 4 | 0 | 9 | 1 | 0 | 9.3 | 2.5 | 12.0 | 7.7 | 1.5 | 3.1 | 1.31 |
| Oscar Villarreal |   | mr | 26 | 2 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 10.0 | 4.1 | 14.6 | 5.0 | 2.9 | 1.2 | 1.57 |
| Ron Villone* |   | mr | 38 | 0 | 0 | 2 | 2 | 2 | 0 | 2 | 3 | 0 | 8.1 | 6.7 | 15.1 | 9.0 | 0.7 | 1.4 | 1.64 |
| Luis Vizcaino |   | mr | 33 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 0 | 9.4 | 3.7 | 13.3 | 9.6 | 2.0 | 2.6 | 1.46 |
| Edinson Volquez | LON | sp | 24 | 21 | 12 | 5 | 14 | 10 | 1 | 6 | 5 | 0 | 7.7 | 4.3 | 12.6 | 9.5 | 0.6 | 2.2 | 1.33 |
| Chris Volstad | MAD | sp | 21 | 12 | 2 | 4 | 5 | 0 | 0 | 6 | 1 | 0 | 8.1 | 3.8 | 12.5 | 5.5 | 0.3 | 1.4 | 1.33 |
| Cory Wade | Pal | mr | 25 | 2 | 0 | 3 | 4 | 2 | 0 | 2 | 1 | 0 | 6.4 | 1.9 | 8.8 | 6.4 | 0.9 | 3.4 | 0.93 |
| Doug Waechter |   | mr | 27 | 6 | 1 | 3 | 2 | 2 | 0 | 2 | 2 | 0 | 9.0 | 3.0 | 12.2 | 6.5 | 1.0 | 2.2 | 1.33 |
| Billy Wagner* | BT | cl | 36 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 6.1 | 1.9 | 8.0 | 10.0 | 0.8 | 5.2 | 0.89 |
| Adam Wainwright | MAD | sp | 26 | 2 | 4 | 1 | 3 | 3 | 0 | 6 | 4 | 0 | 8.3 | 2.3 | 10.8 | 6.2 | 0.8 | 2.7 | 1.18 |
| Tim Wakefield | OTR | sp | 41 | 27 | 10 | 0 | 13 | 12 | 0 | 2 | 4 | 0 | 7.7 | 3.0 | 11.3 | 5.8 | 1.2 | 2.0 | 1.18 |
| Jamie Walker* | OTR | mr | 36 | 2 | 1 | 3 | 1 | 2 | 0 | 1 | 2 | 0 | 12.6 | 2.6 | 15.4 | 5.7 | 2.8 | 2.2 | 1.68 |
| Tyler Walker |   | mr | 32 | 2 | 1 | 3 | 1 | 5 | 0 | 2 | 1 | 0 | 7.9 | 3.5 | 11.6 | 8.3 | 1.2 | 2.3 | 1.27 |
| Les Walrond* |   | mr | 31 | 0 | 1 | 4 | 0 | 2 | 0 | 2 | 0 | 0 | 11.3 | 7.8 | 19.2 | 10.5 | 0.0 | 1.3 | 2.13 |
| Chien-Ming Wang | MID | sp | 28 | 8 | 3 | 1 | 3 | 0 | 0 | 0 | 3 | 0 | 8.5 | 3.3 | 12.1 | 5.1 | 0.4 | 1.5 | 1.32 |
| Jarrod Washburn* |   | sp | 33 | 5 | 4 | 2 | 7 | 2 | 0 | 6 | 5 | 0 | 10.2 | 2.9 | 13.5 | 5.1 | 1.1 | 1.7 | 1.46 |
| Ehren Wassermann |   | mr | 27 | 5 | 1 | 4 | 1 | 1 | 0 | 4 | 1 | 0 | 12.4 | 6.4 | 19.2 | 4.1 | 0.0 | 0.6 | 2.08 |
| Chris Waters* |   | sp | 27 | 3 | 0 | 0 | 3 | 1 | 1 | 0 | 3 | 0 | 9.7 | 4.0 | 14.2 | 4.6 | 1.3 | 1.1 | 1.53 |
| David Weathers |   | mr | 38 | 3 | 0 | 8 | 3 | 1 | 1 | 2 | 1 | 0 | 9.9 | 3.9 | 14.1 | 6.0 | 0.8 | 1.5 | 1.53 |
| Jered Weaver | OTR | sp | 25 | 20 | 5 | 4 | 6 | 3 | 0 | 1 | 4 | 0 | 8.8 | 2.8 | 11.9 | 7.7 | 1.0 | 2.8 | 1.28 |
| Brandon Webb | TON | sp | 29 | 24 | 10 | 5 | 12 | 8 | 1 | 8 | 9 | 0 | 8.2 | 2.6 | 11.2 | 7.3 | 0.5 | 2.8 | 1.20 |
| Todd Wellemeyer | Pal | sp | 29 | 7 | 6 | 1 | 7 | 7 | 1 | 6 | 6 | 0 | 8.4 | 2.9 | 11.6 | 6.3 | 1.2 | 2.2 | 1.25 |
| Jared Wells |   | mr | 26 | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 0 | 0 | 11.9 | 7.6 | 19.4 | 5.4 | 2.2 | 0.7 | 2.16 |
| Kip Wells |   | mr | 31 | 1 | 2 | 2 | 2 | 3 | 0 | 3 | 0 | 0 | 9.3 | 7.2 | 17.0 | 7.4 | 1.0 | 1.0 | 1.83 |
| Randy Wells |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 5.1 | 5.1 | 1.7 | 0.0 | 0.3 | 0.56 |
| Jake Westbrook |   | sp | 30 | 0 | 2 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 8.6 | 1.8 | 10.6 | 4.9 | 1.3 | 2.7 | 1.15 |
| Dan Wheeler | Pal | mr | 30 | 1 | 1 | 4 | 0 | 1 | 0 | 0 | 2 | 0 | 6.0 | 3.0 | 9.0 | 7.2 | 1.4 | 2.4 | 0.99 |
| Bill White* |   | mr | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 15.8 | 24.8 | 40.5 | 2.3 | 2.3 | 0.1 | 4.50 |
| Dontrelle Willis* |   | sp | 26 | 0 | 0 | 1 | 1 | 5 | 1 | 0 | 0 | 0 | 6.8 | 13.1 | 20.3 | 6.8 | 1.5 | 0.5 | 2.21 |
| Brian Wilson | MUL | cl | 26 | 2 | 1 | 4 | 3 | 2 | 0 | 2 | 5 | 0 | 9.0 | 4.0 | 13.4 | 9.7 | 1.0 | 2.4 | 1.44 |
| C.J. Wilson* | ROK | cl | 27 | 1 | 1 | 2 | 2 | 3 | 0 | 1 | 1 | 0 | 9.5 | 5.2 | 15.2 | 8.0 | 1.6 | 1.5 | 1.64 |
| Matt Wise |   | mr | 32 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.9 | 3.9 | 16.7 | 7.7 | 2.6 | 2.0 | 1.86 |
| Randy Wolf* | CCL | sp | 31 | 8 | 5 | 4 | 12 | 3 | 0 | 10 | 4 | 0 | 9.0 | 3.4 | 13.0 | 7.7 | 1.0 | 2.3 | 1.38 |
| Brian Wolfe |   | mr | 27 | 1 | 0 | 1 | 0 | 1 | 0 | 2 | 1 | 0 | 7.4 | 2.5 | 9.8 | 5.7 | 0.8 | 2.3 | 1.09 |
| Kerry Wood | MUL | cl | 31 | 1 | 0 | 4 | 7 | 1 | 0 | 2 | 2 | 0 | 7.3 | 2.4 | 10.7 | 11.4 | 0.4 | 4.7 | 1.09 |
| Jake Woods* |   | mr | 26 | 0 | 0 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 10.4 | 5.2 | 16.1 | 4.3 | 2.4 | 0.8 | 1.74 |
| Mark Worrell |   | mr | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 12.7 | 6.4 | 19.1 | 6.4 | 1.6 | 1.0 | 2.12 |
| Jamey Wright |   | mr | 33 | 9 | 1 | 3 | 8 | 5 | 0 | 3 | 4 | 0 | 9.9 | 3.7 | 14.5 | 6.4 | 0.5 | 1.7 | 1.52 |
| Wesley Wright* |   | mr | 23 | 5 | 0 | 4 | 4 | 2 | 1 | 1 | 1 | 0 | 7.3 | 5.5 | 13.4 | 9.2 | 1.3 | 1.7 | 1.42 |
| Michael Wuertz | ROK | mr | 29 | 4 | 3 | 2 | 0 | 2 | 0 | 1 | 3 | 0 | 8.9 | 4.0 | 12.9 | 6.0 | 0.8 | 1.5 | 1.43 |
| Keiichi Yabu |   | mr | 39 | 3 | 0 | 4 | 8 | 5 | 1 | 3 | 0 | 0 | 8.3 | 4.2 | 13.6 | 6.4 | 0.4 | 1.5 | 1.40 |
| Yasuhiko Yabuta |   | mr | 35 | 4 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 9.8 | 4.1 | 13.9 | 6.0 | 1.4 | 1.5 | 1.54 |
| Tyler Yates |   | mr | 30 | 4 | 1 | 4 | 2 | 5 | 0 | 4 | 1 | 0 | 8.8 | 5.0 | 14.1 | 7.7 | 0.7 | 1.5 | 1.54 |
| Chris Young | COP | sp | 29 | 15 | 2 | 4 | 1 | 3 | 1 | 4 | 1 | 0 | 7.4 | 4.2 | 11.7 | 8.2 | 1.1 | 1.9 | 1.29 |
| Carlos Zambrano | CCL | sp | 27 | 10 | 9 | 1 | 6 | 4 | 0 | 5 | 0 | 0 | 8.2 | 3.4 | 11.9 | 6.2 | 0.9 | 1.8 | 1.29 |
| Brad Ziegler | CRH | mr | 28 | 1 | 0 | 3 | 1 | 0 | 0 | 4 | 3 | 0 | 7.1 | 3.3 | 10.6 | 4.5 | 0.3 | 1.4 | 1.16 |
| Charlie Zink |   | sp | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 22.8 | 2.1 | 24.9 | 2.1 | 0.0 | 1.0 | 2.77 |
| Barry Zito* |   | sp | 30 | 6 | 4 | 10 | 4 | 3 | 0 | 8 | 14 | 0 | 9.3 | 5.1 | 14.6 | 6.0 | 0.8 | 1.2 | 1.60 |
| Joel Zumaya |   | mr | 23 | 1 | 0 | 4 | 0 | 6 | 0 | 0 | 1 | 0 | 9.3 | 8.5 | 17.7 | 8.5 | 1.2 | 1.0 | 1.97 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | EDG | mr | 26 | .822 | 135 | .333 | 113 | .496 | 118 | .518 | 34.1 | 6.4 | 5.68 | 5.63 |
| Jeremy Accardo |   | mr | 26 | .857 | 45 | .311 | 29 | .518 | 30 | .536 | 8.1 | 5.6 | 5.35 | 4.88 |
| Alfredo Aceves |   | sp | 25 | .673 | 90 | .233 | 52 | .433 | 52 | .433 | 11.4 | 3.4 | 3.08 | 3.23 |
| Manny Acosta |   | mr | 27 | .745 | 161 | .255 | 105 | .465 | 106 | .469 | 27.4 | 4.7 | 4.18 | 4.12 |
| Mike Adams | MUL | mr | 29 | .609 | 159 | .264 | 100 | .386 | 100 | .386 | 22.7 | 3.2 | 2.82 | 2.38 |
| Nick Adenhart |   | sp | 21 | .972 | 46 | .391 | 37 | .587 | 37 | .587 | 12.2 | 9.4 | 8.21 | 9.55 |
| Jon Adkins |   | mr | 30 | 1.050 | 8 | .375 | 10 | .667 | 10 | .667 | 2.7 | 7.2 | 5.92 | 8.64 |
| Jeremy Affeldt* | CRH | mr | 29 | .733 | 218 | .317 | 148 | .442 | 151 | .451 | 40.2 | 4.6 | 4.16 | 3.98 |
| Jonathan Albaladejo |   | mr | 25 | .839 | 38 | .368 | 30 | .517 | 30 | .517 | 7.9 | 5.2 | 4.71 | 4.82 |
| Matt Albers |   | mr | 25 | .655 | 154 | .253 | 81 | .389 | 83 | .399 | 18.9 | 3.4 | 3.12 | 3.62 |
| Greg Aquino |   | mr | 30 | 1.114 | 33 | .485 | 33 | .611 | 35 | .648 | 14.7 | 15.3 | 12.79 | 13.24 |
| Alberto Arias |   | mr | 24 | .754 | 69 | .319 | 42 | .442 | 44 | .463 | 11.6 | 4.9 | 4.35 | 4.77 |
| Tony Armas |   | mr | 30 | .951 | 28 | .321 | 22 | .595 | 22 | .595 | 7.4 | 8.0 | 7.19 | 5.65 |
| Jose Arredondo | COP | mr | 24 | .533 | 163 | .239 | 81 | .332 | 82 | .336 | 15.5 | 2.2 | 2.06 | 2.08 |
| Bronson Arroyo | BT | sp | 31 | .811 | 605 | .314 | 433 | .497 | 439 | .504 | 123.3 | 5.5 | 4.99 | 4.83 |
| Jose Ascanio |   | mr | 23 | 1.057 | 21 | .333 | 18 | .600 | 19 | .633 | 7.0 | 11.1 | 9.96 | 8.81 |
| Luis Ayala |   | mr | 30 | .788 | 248 | .310 | 157 | .469 | 161 | .481 | 45.5 | 5.4 | 4.87 | 4.76 |
| Brandon Backe |   | sp | 30 | .920 | 512 | .324 | 441 | .583 | 445 | .589 | 134.0 | 7.3 | 6.51 | 6.67 |
| Burke Badenhop |   | sp | 25 | .813 | 152 | .316 | 106 | .486 | 109 | .500 | 32.3 | 6.1 | 5.53 | 5.74 |
| Cha Seung Baek |   | sp | 28 | .765 | 446 | .287 | 285 | .473 | 288 | .478 | 77.1 | 4.9 | 4.43 | 4.15 |
| Homer Bailey |   | sp | 22 | 1.024 | 137 | .372 | 109 | .606 | 109 | .606 | 41.6 | 10.4 | 9.27 | 9.31 |
| Scott Baker | BON | sp | 26 | .675 | 497 | .284 | 291 | .414 | 294 | .418 | 71.8 | 3.8 | 3.37 | 3.31 |
| John Bale* |   | mr | 34 | .721 | 89 | .315 | 45 | .409 | 45 | .409 | 11.8 | 3.9 | 3.58 | 3.54 |
| Collin Balester |   | sp | 22 | .827 | 262 | .305 | 179 | .500 | 185 | .517 | 53.1 | 5.9 | 5.37 | 5.40 |
| Grant Balfour | COP | mr | 30 | .463 | 115 | .217 | 69 | .308 | 69 | .308 | 12.3 | 1.9 | 1.71 | 1.38 |
| Josh Banks |   | sp | 25 | .813 | 282 | .291 | 181 | .487 | 184 | .495 | 55.0 | 5.9 | 5.22 | 4.97 |
| Brian Bannister |   | sp | 27 | .826 | 604 | .308 | 409 | .504 | 416 | .513 | 122.1 | 6.0 | 5.41 | 5.34 |
| Jimmy Barthmaier |   | sp | 24 | 1.075 | 36 | .361 | 35 | .660 | 35 | .660 | 12.5 | 10.9 | 9.80 | 11.15 |
| Brian Bass |   | mr | 26 | .801 | 295 | .292 | 190 | .490 | 195 | .503 | 50.9 | 5.1 | 4.62 | 4.89 |
| Miguel Batista |   | mr | 37 | .908 | 379 | .306 | 312 | .561 | 318 | .572 | 102.7 | 8.0 | 7.24 | 6.92 |
| Rick Bauer |   | mr | 31 | 1.137 | 22 | .409 | 22 | .733 | 22 | .733 | 8.3 | 12.5 | 11.24 | 9.38 |
| Denny Bautista |   | mr | 27 | .829 | 177 | .311 | 139 | .513 | 141 | .520 | 38.9 | 5.9 | 5.23 | 5.58 |
| Yorman Bazardo |   | mr | 23 | 1.386 | 12 | .583 | 16 | .800 | 16 | .800 | 6.9 | 20.7 | 18.65 | 17.55 |
| T.J. Beam |   | mr | 27 | .784 | 147 | .252 | 97 | .487 | 99 | .497 | 26.9 | 5.3 | 4.77 | 4.12 |
| Josh Beckett | Pal | sp | 28 | .700 | 492 | .315 | 304 | .419 | 313 | .432 | 80.3 | 4.1 | 3.73 | 3.45 |
| Erik Bedard* | GEO | sp | 29 | .697 | 225 | .271 | 151 | .435 | 155 | .447 | 37.1 | 4.1 | 3.71 | 3.82 |
| Joe Beimel* |   | mr | 31 | .672 | 158 | .316 | 81 | .379 | 84 | .393 | 22.0 | 4.0 | 3.64 | 3.70 |
| Matt Belisle |   | sp | 28 | .917 | 118 | .364 | 78 | .549 | 78 | .549 | 26.5 | 7.7 | 7.22 | 6.87 |
| Heath Bell | MUL | mr | 30 | .639 | 217 | .281 | 125 | .386 | 128 | .395 | 31.1 | 3.6 | 3.23 | 2.93 |
| Francis Beltran |   | mr | 28 | .839 | 38 | .263 | 31 | .554 | 31 | .554 | 8.0 | 5.5 | 4.97 | 5.23 |
| Armando Benitez |   | mr | 35 | .814 | 12 | .083 | 16 | .615 | 16 | .615 | 3.5 | 4.7 | 4.44 | 3.68 |
| Jeff Bennett | TON | mr | 28 | .672 | 292 | .277 | 165 | .394 | 172 | .411 | 41.4 | 3.8 | 3.44 | 3.62 |
| Joaquin Benoit | OTR | mr | 30 | .769 | 125 | .272 | 105 | .502 | 105 | .502 | 27.6 | 5.4 | 4.97 | 5.02 |
| Jason Bergmann |   | sp | 26 | .811 | 445 | .288 | 310 | .505 | 311 | .507 | 89.7 | 5.7 | 5.20 | 4.88 |
| Rafael Betancourt | GEO | mr | 33 | .789 | 209 | .311 | 151 | .489 | 151 | .489 | 44.3 | 5.6 | 5.05 | 4.53 |
| Randor Bierd |   | mr | 24 | .869 | 128 | .352 | 91 | .511 | 94 | .528 | 30.3 | 7.4 | 6.69 | 6.40 |
| Chad Billingsley | TON | sp | 23 | .687 | 556 | .313 | 355 | .413 | 363 | .423 | 90.8 | 4.1 | 3.67 | 3.62 |
| Kurt Birkins* |   | mr | 27 | .432 | 25 | .200 | 10 | .270 | 10 | .270 | 1.3 | 1.2 | 1.05 | 1.53 |
| Nick Blackburn |   | sp | 26 | .771 | 658 | .305 | 378 | .459 | 385 | .468 | 102.4 | 4.7 | 4.29 | 4.48 |
| Joe Blanton |   | sp | 27 | .758 | 652 | .290 | 400 | .468 | 404 | .473 | 108.9 | 4.9 | 4.46 | 4.33 |
| Jerry Blevins* |   | mr | 24 | .639 | 103 | .291 | 59 | .378 | 62 | .397 | 14.1 | 3.4 | 3.03 | 3.00 |
| Mitchell Boggs |   | sp | 24 | .919 | 122 | .303 | 93 | .567 | 95 | .579 | 30.0 | 7.9 | 7.14 | 7.17 |
| Jeremy Bonderman |   | sp | 25 | .771 | 227 | .291 | 149 | .467 | 152 | .476 | 40.0 | 5.0 | 4.54 | 5.14 |
| Eddie Bonine |   | sp | 27 | .871 | 98 | .337 | 59 | .504 | 61 | .521 | 16.8 | 5.5 | 5.11 | 5.82 |
| Boof Bonser |   | mr | 26 | .775 | 382 | .322 | 252 | .474 | 253 | .476 | 74.6 | 5.5 | 5.10 | 4.84 |
| Chris Bootcheck |   | mr | 29 | .992 | 62 | .452 | 53 | .589 | 53 | .589 | 20.8 | 11.7 | 10.55 | 11.28 |
| Dave Borkowski |   | mr | 31 | 1.006 | 125 | .360 | 107 | .618 | 108 | .624 | 37.1 | 9.4 | 8.34 | 8.20 |
| Joe Borowski |   | cl | 37 | .978 | 61 | .328 | 50 | .610 | 50 | .610 | 18.6 | 10.1 | 9.05 | 7.86 |
| Michael Bowden |   | sp | 21 | .935 | 18 | .389 | 13 | .591 | 13 | .591 | 4.5 | 8.6 | 7.22 | 4.92 |
| Cedrick Bowers* |   | mr | 30 | 1.323 | 20 | .450 | 26 | .788 | 27 | .818 | 10.5 | 15.7 | 12.75 | 13.72 |
| Micah Bowie* |   | mr | 33 | .970 | 28 | .357 | 22 | .579 | 23 | .605 | 7.0 | 7.6 | 7.12 | 6.98 |
| Blaine Boyer |   | mr | 26 | .774 | 209 | .301 | 151 | .482 | 153 | .489 | 42.9 | 5.3 | 4.82 | 4.19 |
| Dallas Braden* |   | sp | 24 | .771 | 225 | .307 | 140 | .465 | 142 | .472 | 39.0 | 5.1 | 4.41 | 4.63 |
| Chad Bradford | MID | mr | 33 | .653 | 204 | .275 | 87 | .361 | 89 | .369 | 20.1 | 3.0 | 2.74 | 3.24 |
| Bill Bray* |   | mr | 25 | .779 | 132 | .348 | 103 | .479 | 104 | .484 | 29.6 | 5.6 | 5.10 | 4.57 |
| Yhency Brazoban |   | mr | 28 | .976 | 10 | .400 | 10 | .625 | 10 | .625 | 2.9 | 7.9 | 7.88 | 7.51 |
| Craig Breslow* | MID | mr | 27 | .516 | 130 | .254 | 58 | .307 | 58 | .307 | 11.3 | 2.2 | 1.95 | 2.12 |
| Chris Britton |   | mr | 25 | .941 | 78 | .308 | 64 | .610 | 64 | .610 | 20.3 | 8.2 | 7.15 | 6.22 |
| Lance Broadway |   | mr | 24 | 1.002 | 50 | .320 | 43 | .652 | 43 | .652 | 13.6 | 8.5 | 7.87 | 7.80 |
| Doug Brocail |   | mr | 41 | .682 | 190 | .289 | 119 | .416 | 122 | .427 | 29.9 | 3.9 | 3.53 | 3.45 |
| Andrew Brown |   | mr | 27 | .609 | 94 | .213 | 58 | .395 | 59 | .401 | 11.8 | 3.0 | 2.74 | 2.96 |
| Jonathan Broxton | CCL | mr | 24 | .595 | 165 | .315 | 101 | .354 | 104 | .365 | 23.4 | 3.0 | 2.74 | 2.48 |
| Brian Bruney |   | mr | 26 | .493 | 85 | .188 | 44 | .321 | 45 | .328 | 8.9 | 2.4 | 2.11 | 1.75 |
| Clay Buchholz | COP | sp | 23 | .844 | 231 | .355 | 185 | .518 | 187 | .524 | 57.5 | 6.8 | 6.13 | 6.40 |
| Taylor Buchholz | TON | mr | 26 | .550 | 182 | .220 | 90 | .342 | 92 | .350 | 18.4 | 2.4 | 2.24 | 1.87 |
| Billy Buckner |   | mr | 24 | .874 | 40 | .325 | 32 | .542 | 33 | .559 | 8.4 | 5.4 | 4.84 | 5.72 |
| Mark Buehrle* | BON | sp | 29 | .747 | 699 | .312 | 413 | .450 | 418 | .455 | 106.4 | 4.3 | 3.94 | 4.12 |
| Francisley Bueno* |   | mr | 27 | 1.128 | 10 | .400 | 9 | .692 | 9 | .692 | 3.8 | 14.7 | 13.23 | 14.73 |
| Ryan Bukvich |   | mr | 30 | 1.208 | 17 | .412 | 23 | .767 | 23 | .767 | 8.7 | 14.6 | 13.15 | 14.88 |
| Jason Bulger |   | mr | 29 | .856 | 39 | .308 | 40 | .548 | 42 | .575 | 11.8 | 6.6 | 5.96 | 5.50 |
| Bryan Bullington |   | sp | 27 | .836 | 41 | .268 | 32 | .533 | 33 | .550 | 8.6 | 5.3 | 4.76 | 4.63 |
| A.J. Burnett | TON | sp | 31 | .710 | 612 | .314 | 415 | .434 | 424 | .443 | 110.6 | 4.4 | 4.05 | 3.78 |
| Sean Burnett* | WIZ | mr | 25 | .816 | 168 | .298 | 127 | .502 | 129 | .510 | 34.9 | 5.5 | 5.00 | 5.23 |
| Brian Burres* |   | sp | 27 | .854 | 460 | .322 | 306 | .513 | 312 | .523 | 99.3 | 7.0 | 6.20 | 6.03 |
| Jared Burton | MAD | mr | 27 | .712 | 166 | .301 | 112 | .436 | 114 | .444 | 30.1 | 4.6 | 4.16 | 3.93 |
| Dave Bush | OTR | sp | 28 | .715 | 567 | .236 | 344 | .451 | 354 | .464 | 84.2 | 4.0 | 3.69 | 3.44 |
| Paul Byrd |   | sp | 37 | .801 | 607 | .285 | 374 | .491 | 381 | .501 | 106.1 | 5.4 | 4.78 | 4.70 |
| Tim Byrdak* |   | mr | 34 | .777 | 149 | .235 | 121 | .511 | 123 | .519 | 31.3 | 5.1 | 4.59 | 4.18 |
| Daniel Cabrera |   | sp | 27 | .826 | 594 | .295 | 403 | .491 | 421 | .513 | 124.1 | 6.2 | 5.59 | 5.77 |
| Fernando Cabrera |   | mr | 26 | .938 | 75 | .307 | 81 | .614 | 81 | .614 | 24.7 | 7.8 | 7.08 | 7.24 |
| Matt Cain | LON | sp | 23 | .728 | 630 | .297 | 419 | .449 | 426 | .457 | 111.2 | 4.6 | 4.14 | 3.84 |
| Kiko Calero |   | mr | 33 | .594 | 10 | .300 | 8 | .400 | 8 | .400 | 1.7 | 3.3 | 3.01 | 2.35 |
| Kevin Cameron |   | mr | 28 | .724 | 35 | .286 | 20 | .435 | 20 | .435 | 5.2 | 4.6 | 4.25 | 3.64 |
| Shawn Camp |   | mr | 32 | .694 | 120 | .317 | 68 | .410 | 70 | .422 | 17.8 | 4.1 | 3.67 | 3.47 |
| Jorge Campillo | WIZ | sp | 29 | .734 | 491 | .285 | 296 | .452 | 297 | .453 | 78.0 | 4.5 | 3.98 | 3.55 |
| Jose Capellan |   | mr | 27 | .778 | 7 | .429 | 4 | .444 | 4 | .444 | 1.3 | 6.0 | 5.40 | 4.47 |
| Matt Capps | MUL | cl | 24 | .633 | 160 | .262 | 80 | .379 | 82 | .389 | 19.0 | 3.2 | 2.87 | 2.39 |
| Jesse Carlson* | BON | mr | 27 | .620 | 152 | .230 | 93 | .392 | 96 | .405 | 19.7 | 3.0 | 2.66 | 2.32 |
| Buddy Carlyle | LON | mr | 30 | .661 | 168 | .280 | 106 | .409 | 107 | .413 | 25.4 | 3.7 | 3.28 | 3.03 |
| Fausto Carmona |   | sp | 24 | .759 | 405 | .294 | 249 | .454 | 258 | .470 | 66.6 | 4.8 | 4.47 | 5.07 |
| Andrew Carpenter |   | mr | 23 | .833 | 3 | .333 | 2 | .400 | 2 | .400 | 0.6 | 5.5 | 4.92 | 3.46 |
| Chris Carpenter | TON | sp | 33 | .667 | 52 | .308 | 23 | .365 | 23 | .365 | 5.8 | 3.4 | 3.08 | 3.19 |
| D.J. Carrasco |   | mr | 31 | .611 | 107 | .262 | 55 | .348 | 60 | .380 | 13.1 | 3.1 | 2.75 | 2.94 |
| Santiago Casilla | OTR | mr | 27 | .810 | 158 | .348 | 109 | .476 | 112 | .489 | 34.2 | 6.1 | 5.51 | 5.34 |
| Jack Cassel |   | mr | 27 | .883 | 104 | .317 | 72 | .545 | 73 | .553 | 20.6 | 6.1 | 5.50 | 5.63 |
| Alberto Castillo* |   | mr | 32 | .758 | 78 | .308 | 51 | .421 | 58 | .479 | 16.5 | 5.7 | 5.14 | 5.36 |
| Shawn Chacon |   | sp | 30 | .845 | 262 | .275 | 201 | .537 | 203 | .543 | 55.2 | 5.8 | 5.22 | 5.28 |
| Joba Chamberlain | BT | mr | 22 | .617 | 253 | .324 | 154 | .369 | 156 | .374 | 37.3 | 3.4 | 3.01 | 3.04 |
| Jesse Chavez |   | mr | 24 | .900 | 47 | .383 | 39 | .527 | 39 | .527 | 13.9 | 8.3 | 7.50 | 6.76 |
| Rocky Cherry |   | mr | 28 | .873 | 50 | .240 | 48 | .565 | 49 | .576 | 13.3 | 6.5 | 6.34 | 5.80 |
| Matt Chico* |   | sp | 25 | .946 | 160 | .331 | 128 | .584 | 129 | .589 | 41.0 | 7.7 | 6.91 | 6.67 |
| Vinnie Chulk |   | mr | 29 | .800 | 107 | .252 | 70 | .504 | 72 | .518 | 19.8 | 5.5 | 5.07 | 4.36 |
| Tyler Clippard |   | sp | 23 | .957 | 31 | .323 | 30 | .625 | 30 | .625 | 9.2 | 8.3 | 7.22 | 6.90 |
| Todd Coffey |   | mr | 27 | .822 | 88 | .307 | 57 | .491 | 58 | .500 | 15.8 | 5.2 | 4.80 | 5.19 |
| Phil Coke* |   | mr | 25 | .392 | 36 | .222 | 12 | .231 | 12 | .231 | 1.6 | 1.0 | 0.89 | 0.89 |
| Jesus Colome |   | mr | 30 | .695 | 208 | .264 | 131 | .420 | 135 | .433 | 33.8 | 4.2 | 3.86 | 3.86 |
| Bartolo Colon |   | sp | 35 | .759 | 129 | .302 | 77 | .445 | 79 | .457 | 22.3 | 5.0 | 4.63 | 4.53 |
| Clay Condrey |   | mr | 32 | .792 | 242 | .326 | 143 | .472 | 145 | .479 | 39.7 | 5.1 | 4.66 | 4.77 |
| Jose Contreras |   | sp | 36 | .734 | 402 | .294 | 231 | .443 | 234 | .448 | 65.4 | 4.8 | 4.38 | 4.13 |
| Aaron Cook | MAD | sp | 29 | .739 | 725 | .308 | 385 | .435 | 389 | .439 | 101.8 | 4.3 | 3.90 | 3.92 |
| Roy Corcoran | EDG | mr | 28 | .649 | 238 | .269 | 123 | .389 | 125 | .396 | 29.0 | 3.5 | 3.23 | 3.24 |
| Chad Cordero |   | mr | 26 | .778 | 14 | .429 | 10 | .455 | 10 | .455 | 3.1 | 6.4 | 5.75 | 6.09 |
| Francisco Cordero | CRH | cl | 33 | .682 | 182 | .302 | 128 | .417 | 131 | .427 | 32.7 | 4.1 | 3.76 | 3.86 |
| Bryan Corey |   | mr | 34 | .820 | 156 | .288 | 100 | .505 | 100 | .505 | 29.8 | 6.0 | 5.37 | 4.90 |
| Lance Cormier |   | mr | 27 | .727 | 234 | .316 | 138 | .433 | 139 | .436 | 38.3 | 4.8 | 4.33 | 4.55 |
| Manuel Corpas |   | mr | 25 | .777 | 264 | .326 | 158 | .457 | 160 | .462 | 45.3 | 5.1 | 4.61 | 4.55 |
| Kevin Correia | MUL | sp | 27 | .857 | 382 | .330 | 266 | .518 | 270 | .525 | 81.9 | 6.6 | 6.03 | 6.19 |
| Neal Cotts* | CRH | mr | 28 | .786 | 96 | .323 | 78 | .488 | 79 | .494 | 22.3 | 5.5 | 5.06 | 4.87 |
| Jesse Crain | BON | mr | 26 | .744 | 187 | .299 | 125 | .466 | 126 | .470 | 33.9 | 4.9 | 4.39 | 3.93 |
| Francisco Cruceta |   | mr | 26 | .880 | 33 | .333 | 30 | .536 | 30 | .536 | 9.0 | 6.9 | 6.22 | 7.19 |
| Juan Cruz | TON | mr | 29 | .658 | 105 | .276 | 91 | .423 | 94 | .437 | 20.9 | 3.7 | 3.27 | 3.25 |
| Johnny Cueto | Pal | sp | 22 | .803 | 500 | .298 | 378 | .492 | 392 | .510 | 108.1 | 5.5 | 5.03 | 4.95 |
| John Danks* | EDG | sp | 23 | .674 | 569 | .293 | 331 | .412 | 335 | .417 | 83.1 | 3.8 | 3.45 | 3.26 |
| Kyle Davies |   | sp | 24 | .762 | 361 | .307 | 227 | .466 | 229 | .470 | 62.6 | 5.0 | 4.49 | 4.46 |
| Doug Davis* |   | sp | 32 | .775 | 457 | .322 | 302 | .465 | 306 | .471 | 86.0 | 5.3 | 4.77 | 4.77 |
| Jason Davis |   | mr | 28 | .796 | 118 | .305 | 69 | .451 | 72 | .471 | 20.2 | 5.2 | 4.80 | 5.31 |
| Eulogio De La Cruz |   | mr | 24 | 1.175 | 36 | .361 | 38 | .717 | 38 | .717 | 15.3 | 14.8 | 13.78 | 13.08 |
| Jorge De La Rosa* | MUL | sp | 27 | .760 | 361 | .319 | 263 | .461 | 270 | .473 | 73.4 | 5.1 | 4.58 | 4.50 |
| Valerio de los Santos* |   | sp | 35 | .770 | 18 | .278 | 21 | .525 | 21 | .525 | 5.1 | 5.8 | 5.21 | 6.76 |
| Manny Delcarmen | GEO | mr | 26 | .605 | 199 | .251 | 114 | .371 | 117 | .381 | 27.1 | 3.3 | 2.96 | 2.51 |
| Jesus Delgado |   | mr | 24 | .611 | 7 | .143 | 4 | .400 | 4 | .400 | 0.9 | 4.1 | 3.73 | 4.47 |
| Ryan Dempster | CRH | sp | 31 | .642 | 572 | .280 | 337 | .394 | 344 | .402 | 79.7 | 3.5 | 3.13 | 3.03 |
| Matt DeSalvo |   | mr | 27 | 1.410 | 14 | .786 | 13 | .722 | 13 | .722 | 7.7 | 34.6 | 31.10 | 43.01 |
| Elmer Dessens |   | mr | 37 | 1.388 | 19 | .474 | 21 | .808 | 21 | .808 | 10.6 | 23.7 | 21.37 | 18.65 |
| Joey Devine | BT | mr | 24 | .395 | 106 | .217 | 41 | .241 | 41 | .241 | 6.4 | 1.3 | 1.13 | 1.09 |
| Joselo Diaz |   | mr | 28 | .833 | 2 | .500 | 2 | .333 | 3 | .500 | 1.3 | 11.5 | 10.37 | 9.51 |
| R.A. Dickey | OTR | mr | 33 | .805 | 374 | .291 | 247 | .494 | 249 | .498 | 71.2 | 5.7 | 5.13 | 5.19 |
| Mark DiFelice |   | mr | 31 | .688 | 50 | .260 | 35 | .449 | 35 | .449 | 8.3 | 3.9 | 3.56 | 3.39 |
| Tim Dillard |   | mr | 24 | .802 | 52 | .288 | 32 | .492 | 32 | .492 | 8.5 | 5.1 | 4.79 | 5.24 |
| Lenny DiNardo* |   | mr | 28 | .846 | 84 | .333 | 56 | .491 | 58 | .509 | 17.7 | 6.6 | 6.22 | 7.21 |
| Scott Dohmann |   | mr | 30 | .862 | 45 | .356 | 35 | .530 | 35 | .530 | 11.2 | 7.0 | 6.19 | 6.03 |
| Freddy Dolsi |   | mr | 25 | .719 | 155 | .303 | 93 | .427 | 96 | .440 | 26.5 | 5.0 | 4.50 | 4.89 |
| Brendan Donnelly |   | mr | 36 | .941 | 49 | .367 | 38 | .551 | 38 | .551 | 13.7 | 9.5 | 8.13 | 8.84 |
| Octavio Dotel |   | mr | 34 | .687 | 150 | .267 | 125 | .434 | 130 | .451 | 33.0 | 4.3 | 3.99 | 3.64 |
| Scott Downs* | EDG | mr | 32 | .590 | 199 | .256 | 101 | .348 | 105 | .362 | 22.3 | 2.8 | 2.55 | 2.47 |
| Justin Duchscherer | COP | sp | 30 | .590 | 409 | .235 | 198 | .355 | 206 | .370 | 43.1 | 2.7 | 2.46 | 2.31 |
| Brandon Duckworth |   | sp | 32 | .751 | 123 | .293 | 75 | .449 | 78 | .467 | 20.4 | 4.8 | 4.35 | 4.52 |
| Zach Duke* |   | sp | 25 | .812 | 669 | .315 | 398 | .480 | 405 | .489 | 122.4 | 5.9 | 5.36 | 4.99 |
| Phil Dumatrait* |   | sp | 26 | .776 | 248 | .302 | 168 | .479 | 170 | .484 | 46.7 | 5.4 | 4.81 | 4.87 |
| Chad Durbin | MAD | mr | 30 | .675 | 258 | .295 | 144 | .395 | 148 | .405 | 33.9 | 3.5 | 3.13 | 3.51 |
| Adam Eaton |   | sp | 30 | .868 | 356 | .326 | 250 | .523 | 256 | .536 | 74.4 | 6.3 | 5.63 | 6.07 |
| Mike Ekstrom |   | mr | 24 | .972 | 32 | .375 | 28 | .596 | 28 | .596 | 9.3 | 9.0 | 7.82 | 9.38 |
| Scott Elarton |   | mr | 32 | .685 | 46 | .348 | 29 | .414 | 29 | .414 | 8.0 | 4.8 | 4.21 | 4.01 |
| Scott Elbert* |   | mr | 22 | 1.067 | 16 | .438 | 20 | .645 | 21 | .677 | 7.7 | 11.5 | 10.38 | 11.46 |
| Alan Embree* |   | mr | 38 | .769 | 173 | .295 | 130 | .481 | 132 | .489 | 34.2 | 4.9 | 4.50 | 4.39 |
| Geno Espineli* |   | mr | 25 | .920 | 48 | .250 | 42 | .609 | 42 | .609 | 11.1 | 6.3 | 5.64 | 6.48 |
| Shawn Estes* |   | sp | 35 | .795 | 153 | .288 | 95 | .480 | 97 | .490 | 27.9 | 5.6 | 5.18 | 5.39 |
| Marco Estrada |   | mr | 24 | .952 | 42 | .310 | 37 | .587 | 39 | .619 | 12.3 | 8.3 | 7.83 | 8.13 |
| Dana Eveland* |   | sp | 24 | .735 | 520 | .312 | 320 | .434 | 332 | .450 | 88.1 | 4.7 | 4.25 | 4.47 |
| Scott Eyre* |   | mr | 36 | .733 | 63 | .333 | 48 | .453 | 50 | .472 | 12.1 | 4.2 | 3.83 | 3.09 |
| Brian Falkenborg |   | mr | 30 | .823 | 67 | .328 | 51 | .500 | 51 | .500 | 15.0 | 6.0 | 5.44 | 6.11 |
| Kyle Farnsworth |   | mr | 32 | .907 | 162 | .340 | 150 | .575 | 151 | .579 | 42.3 | 6.3 | 5.68 | 6.11 |
| Ryan Feierabend* |   | sp | 22 | .997 | 135 | .385 | 112 | .612 | 113 | .617 | 38.4 | 9.0 | 7.85 | 7.83 |
| Scott Feldman | MID | sp | 25 | .814 | 489 | .284 | 323 | .496 | 333 | .512 | 91.3 | 5.4 | 4.89 | 5.03 |
| Pedro Feliciano* | MAD | mr | 31 | .790 | 151 | .331 | 112 | .473 | 115 | .485 | 30.6 | 5.2 | 4.64 | 5.11 |
| Nelson Figueroa |   | mr | 34 | .741 | 144 | .313 | 94 | .445 | 96 | .455 | 27.0 | 5.3 | 4.83 | 4.88 |
| Randy Flores* |   | mr | 32 | .883 | 91 | .352 | 70 | .534 | 71 | .542 | 23.8 | 8.4 | 7.52 | 7.23 |
| Gavin Floyd | TON | sp | 25 | .738 | 624 | .256 | 408 | .465 | 417 | .475 | 107.6 | 4.6 | 4.22 | 3.80 |
| Josh Fogg |   | sp | 31 | .904 | 267 | .300 | 200 | .552 | 206 | .569 | 62.0 | 6.9 | 6.41 | 6.36 |
| Casey Fossum* |   | mr | 30 | .806 | 126 | .317 | 88 | .492 | 91 | .508 | 23.9 | 5.3 | 4.69 | 4.98 |
| Keith Foulke |   | mr | 35 | .810 | 89 | .236 | 70 | .526 | 71 | .534 | 19.0 | 5.5 | 4.97 | 4.49 |
| Chad Fox |   | mr | 37 | .885 | 9 | .111 | 8 | .571 | 8 | .571 | 2.4 | 7.3 | 5.92 | 5.57 |
| Jeff Francis* |   | sp | 27 | .825 | 469 | .305 | 326 | .513 | 329 | .517 | 97.0 | 6.1 | 5.47 | 5.00 |
| Frank Francisco | EDG | mr | 28 | .634 | 148 | .270 | 110 | .417 | 110 | .417 | 26.0 | 3.7 | 3.33 | 2.70 |
| Ryan Franklin |   | mr | 35 | .805 | 252 | .302 | 172 | .497 | 175 | .506 | 49.0 | 5.6 | 5.04 | 4.82 |
| Jason Frasor | MID | mr | 30 | .679 | 129 | .248 | 92 | .442 | 93 | .447 | 22.6 | 4.3 | 3.87 | 3.62 |
| Brian Fuentes* | CCL | cl | 32 | .569 | 148 | .297 | 89 | .348 | 90 | .352 | 20.4 | 2.9 | 2.64 | 2.27 |
| Kazuo Fukumori |   | mr | 31 | 1.441 | 19 | .474 | 23 | .885 | 23 | .885 | 10.9 | 24.6 | 22.13 | 23.91 |
| Jeff Fulchino |   | mr | 28 | .981 | 49 | .388 | 43 | .597 | 44 | .611 | 15.5 | 9.7 | 8.94 | 8.38 |
| Kason Gabbard* |   | sp | 26 | .809 | 185 | .319 | 129 | .490 | 130 | .494 | 35.8 | 5.7 | 5.19 | 6.04 |
| Eric Gagne |   | mr | 32 | .841 | 130 | .269 | 110 | .542 | 112 | .552 | 29.7 | 5.8 | 5.19 | 5.51 |
| Armando Galarraga |   | sp | 26 | .704 | 525 | .236 | 337 | .452 | 343 | .460 | 81.1 | 4.0 | 3.68 | 3.50 |
| Sean Gallagher |   | sp | 22 | .789 | 342 | .307 | 255 | .489 | 261 | .500 | 72.6 | 5.6 | 5.10 | 4.83 |
| Yovani Gallardo | LON | sp | 22 | .723 | 66 | .288 | 43 | .443 | 43 | .443 | 10.8 | 4.1 | 3.63 | 3.66 |
| Freddy Garcia |   | sp | 32 | .702 | 39 | .205 | 28 | .459 | 29 | .475 | 6.4 | 3.8 | 3.45 | 3.61 |
| Jaime Garcia* |   | mr | 21 | .800 | 48 | .208 | 36 | .522 | 37 | .536 | 9.2 | 5.2 | 4.67 | 5.15 |
| Lee Gardner |   | mr | 33 | 1.244 | 28 | .429 | 29 | .763 | 29 | .763 | 12.6 | 17.0 | 15.29 | 14.00 |
| Jon Garland |   | sp | 28 | .819 | 684 | .313 | 421 | .487 | 429 | .497 | 124.0 | 5.7 | 5.11 | 5.18 |
| Matt Garza | GEO | sp | 24 | .683 | 560 | .270 | 321 | .416 | 327 | .424 | 78.9 | 3.8 | 3.46 | 3.47 |
| Chad Gaudin |   | mr | 25 | .734 | 270 | .300 | 170 | .445 | 173 | .453 | 44.1 | 4.4 | 3.97 | 4.06 |
| Geoff Geary | TON | mr | 31 | .570 | 184 | .228 | 92 | .351 | 94 | .359 | 19.4 | 2.7 | 2.45 | 2.32 |
| Josh Geer |   | sp | 25 | .704 | 90 | .300 | 50 | .427 | 50 | .427 | 13.3 | 4.4 | 4.00 | 3.90 |
| Franklyn German |   | mr | 28 | .655 | 65 | .277 | 36 | .387 | 36 | .387 | 9.1 | 3.8 | 3.41 | 3.15 |
| Justin Germano |   | sp | 25 | .857 | 155 | .297 | 102 | .526 | 103 | .531 | 30.4 | 6.1 | 5.64 | 5.69 |
| Dan Giese | BON | mr | 31 | .636 | 139 | .259 | 72 | .387 | 73 | .392 | 19.3 | 3.9 | 3.62 | 2.98 |
| Matt Ginter |   | sp | 30 | .820 | 69 | .319 | 44 | .506 | 44 | .506 | 11.7 | 5.0 | 4.53 | 4.46 |
| Tom Glavine* |   | sp | 42 | .890 | 195 | .287 | 155 | .552 | 156 | .555 | 43.9 | 6.3 | 5.61 | 5.85 |
| Gary Glover |   | mr | 31 | .825 | 178 | .320 | 125 | .508 | 127 | .516 | 34.7 | 5.6 | 5.18 | 5.29 |
| Jimmy Gobble* |   | mr | 26 | .906 | 102 | .333 | 90 | .566 | 92 | .579 | 30.1 | 8.6 | 7.70 | 7.36 |
| Edgar Gonzalez |   | mr | 25 | .873 | 157 | .318 | 116 | .525 | 119 | .538 | 35.9 | 6.7 | 6.06 | 6.16 |
| Enrique Gonzalez |   | mr | 25 | 1.015 | 12 | .333 | 10 | .667 | 10 | .667 | 2.8 | 7.7 | 6.90 | 5.47 |
| Gio Gonzalez* |   | sp | 22 | .911 | 92 | .250 | 96 | .589 | 99 | .607 | 27.8 | 7.1 | 6.63 | 6.54 |
| Mike Gonzalez* |   | cl | 30 | .702 | 77 | .260 | 65 | .458 | 66 | .465 | 15.4 | 4.0 | 3.71 | 3.33 |
| Brian Gordon |   | mr | 29 | .563 | 15 | .267 | 5 | .313 | 5 | .313 | 1.3 | 2.8 | 2.53 | 1.95 |
| Tom Gordon |   | mr | 40 | .783 | 93 | .301 | 70 | .504 | 70 | .504 | 20.1 | 6.0 | 5.49 | 4.77 |
| Tom Gorzelanny* |   | sp | 25 | .909 | 332 | .301 | 282 | .576 | 283 | .578 | 85.0 | 7.2 | 6.53 | 6.86 |
| John Grabow* | TON | mr | 29 | .651 | 213 | .239 | 133 | .413 | 134 | .416 | 30.3 | 3.5 | 3.23 | 3.37 |
| Jeff Gray |   | mr | 26 | 1.053 | 17 | .412 | 15 | .625 | 16 | .667 | 6.1 | 11.7 | 10.50 | 9.48 |
| Sean Green |   | mr | 29 | .690 | 251 | .307 | 142 | .397 | 148 | .413 | 39.3 | 4.3 | 4.03 | 4.09 |
| Kevin Gregg | BT | cl | 30 | .585 | 194 | .247 | 105 | .355 | 109 | .368 | 24.1 | 3.1 | 2.84 | 2.90 |
| Zack Greinke | COP | sp | 24 | .715 | 587 | .308 | 375 | .441 | 379 | .445 | 96.7 | 4.3 | 3.87 | 3.68 |
| Jason Grilli | COP | mr | 31 | .673 | 212 | .307 | 133 | .412 | 135 | .418 | 32.4 | 3.9 | 3.49 | 3.34 |
| Eddie Guardado* |   | mr | 37 | .699 | 171 | .269 | 99 | .436 | 99 | .436 | 24.1 | 3.9 | 3.46 | 3.09 |
| Matt Guerrier | MID | mr | 29 | .802 | 236 | .305 | 174 | .506 | 174 | .506 | 50.8 | 6.0 | 5.39 | 5.20 |
| Carlos Guevara |   | mr | 26 | .801 | 38 | .289 | 30 | .500 | 30 | .500 | 8.9 | 6.2 | 5.84 | 5.68 |
| Jeremy Guthrie | MID | sp | 29 | .694 | 587 | .259 | 342 | .430 | 349 | .438 | 85.5 | 4.0 | 3.63 | 3.59 |
| Angel Guzman |   | mr | 26 | .751 | 28 | .321 | 20 | .455 | 21 | .477 | 5.9 | 5.5 | 4.94 | 4.65 |
| Charlie Haeger |   | mr | 24 | 1.202 | 15 | .400 | 19 | .679 | 21 | .750 | 8.8 | 18.2 | 16.36 | 19.18 |
| Roy Halladay | ROK | sp | 31 | .621 | 712 | .284 | 359 | .364 | 371 | .376 | 85.6 | 3.1 | 2.82 | 2.62 |
| Cole Hamels* | BT | sp | 24 | .657 | 636 | .259 | 380 | .416 | 381 | .417 | 88.5 | 3.5 | 3.15 | 2.76 |
| Jason Hammel | EDG | mr | 25 | .791 | 254 | .283 | 170 | .491 | 172 | .497 | 49.0 | 5.7 | 5.07 | 4.94 |
| Justin Hampson* |   | mr | 28 | .679 | 96 | .313 | 49 | .389 | 49 | .389 | 12.2 | 3.6 | 3.22 | 3.41 |
| Mike Hampton* |   | sp | 35 | .818 | 254 | .287 | 168 | .508 | 169 | .511 | 44.0 | 5.1 | 4.57 | 4.52 |
| Joel Hanrahan | CCL | mr | 26 | .697 | 219 | .292 | 160 | .440 | 161 | .442 | 41.9 | 4.5 | 4.02 | 3.65 |
| Devern Hansack |   | mr | 30 | .603 | 20 | .300 | 9 | .346 | 9 | .346 | 2.0 | 2.7 | 2.46 | 2.08 |
| Craig Hansen |   | mr | 24 | .707 | 144 | .257 | 100 | .446 | 102 | .455 | 26.0 | 4.9 | 4.54 | 5.05 |
| J.A. Happ* |   | sp | 25 | .658 | 94 | .266 | 55 | .399 | 56 | .406 | 14.6 | 4.1 | 3.72 | 3.55 |
| Aaron Harang | GEO | sp | 30 | .838 | 553 | .307 | 418 | .527 | 420 | .530 | 121.1 | 5.9 | 5.32 | 4.83 |
| Rich Harden | COP | sp | 26 | .557 | 339 | .251 | 212 | .356 | 215 | .361 | 44.0 | 2.7 | 2.41 | 2.20 |
| Dan Haren | LON | sp | 27 | .667 | 610 | .303 | 354 | .402 | 360 | .409 | 89.7 | 3.8 | 3.36 | 2.96 |
| Matt Harrison* |   | sp | 22 | .878 | 285 | .309 | 204 | .548 | 206 | .554 | 59.9 | 6.4 | 5.80 | 5.53 |
| Kevin Hart |   | mr | 25 | .917 | 96 | .385 | 77 | .542 | 80 | .563 | 27.1 | 8.7 | 7.93 | 7.48 |
| LaTroy Hawkins |   | mr | 35 | .626 | 179 | .279 | 96 | .381 | 96 | .381 | 22.4 | 3.3 | 2.93 | 2.75 |
| Dirk Hayhurst |   | mr | 27 | .981 | 58 | .431 | 50 | .595 | 50 | .595 | 18.2 | 9.8 | 8.84 | 8.97 |
| Aaron Heilman |   | mr | 29 | .793 | 211 | .308 | 168 | .472 | 177 | .497 | 50.9 | 6.1 | 5.42 | 5.26 |
| Mark Hendrickson* |   | sp | 34 | .786 | 439 | .298 | 278 | .471 | 283 | .480 | 82.5 | 5.6 | 5.00 | 4.78 |
| Sean Henn* |   | mr | 27 | .840 | 28 | .357 | 24 | .511 | 24 | .511 | 7.1 | 6.9 | 6.17 | 7.32 |
| Brad Hennessey |   | mr | 28 | 1.012 | 151 | .364 | 121 | .617 | 122 | .622 | 44.2 | 10.0 | 8.88 | 8.28 |
| Clay Hensley |   | mr | 28 | .738 | 119 | .286 | 79 | .457 | 80 | .462 | 20.8 | 4.8 | 4.31 | 4.23 |
| Matt Herges |   | mr | 38 | .830 | 214 | .346 | 144 | .490 | 149 | .507 | 43.6 | 6.0 | 5.48 | 5.29 |
| Felix Hernandez | ROK | sp | 22 | .727 | 577 | .314 | 377 | .440 | 385 | .449 | 98.7 | 4.4 | 3.99 | 4.05 |
| Fernando Hernandez |   | mr | 23 | .911 | 11 | .364 | 10 | .526 | 11 | .579 | 3.5 | 10.4 | 9.32 | 11.80 |
| Livan Hernandez |   | sp | 33 | .895 | 674 | .344 | 434 | .535 | 436 | .538 | 138.2 | 6.9 | 6.22 | 6.35 |
| Runelvys Hernandez |   | sp | 30 | 1.094 | 68 | .412 | 67 | .684 | 67 | .684 | 24.3 | 11.3 | 10.20 | 9.88 |
| Danny Herrera* |   | mr | 23 | .962 | 23 | .391 | 19 | .514 | 21 | .568 | 7.2 | 8.9 | 7.98 | 7.05 |
| Yoslan Herrera |   | sp | 27 | 1.068 | 76 | .447 | 59 | .590 | 60 | .600 | 24.1 | 11.8 | 10.64 | 10.94 |
| Rich Hill* |   | sp | 28 | .683 | 53 | .208 | 40 | .449 | 41 | .461 | 9.8 | 4.5 | 4.03 | 4.38 |
| Shawn Hill |   | sp | 27 | .878 | 228 | .364 | 155 | .524 | 156 | .527 | 50.9 | 7.2 | 6.52 | 6.04 |
| Mike Hinckley* |   | mr | 25 | .445 | 36 | .222 | 12 | .245 | 13 | .265 | 2.2 | 1.5 | 1.28 | 1.35 |
| Alex Hinshaw* |   | mr | 25 | .736 | 95 | .274 | 82 | .458 | 85 | .475 | 21.8 | 5.0 | 4.45 | 4.43 |
| Jason Hirsh |   | mr | 26 | 1.151 | 33 | .364 | 35 | .761 | 35 | .761 | 13.2 | 13.2 | 12.37 | 10.73 |
| Luke Hochevar |   | sp | 24 | .758 | 430 | .305 | 258 | .456 | 263 | .465 | 72.5 | 5.0 | 4.55 | 4.67 |
| Trevor Hoffman | Pal | cl | 40 | .657 | 117 | .256 | 76 | .422 | 76 | .422 | 17.7 | 3.5 | 3.17 | 2.86 |
| J.P. Howell* | MID | mr | 25 | .579 | 229 | .245 | 132 | .357 | 136 | .368 | 29.0 | 2.8 | 2.63 | 2.51 |
| Bob Howry | WIZ | mr | 34 | .882 | 224 | .344 | 171 | .550 | 173 | .556 | 52.8 | 6.7 | 6.05 | 5.37 |
| Tim Hudson | GEO | sp | 32 | .660 | 435 | .262 | 231 | .403 | 233 | .407 | 53.5 | 3.4 | 3.05 | 2.90 |
| Phil Hughes | COP | sp | 22 | .845 | 115 | .348 | 79 | .503 | 80 | .510 | 26.5 | 7.1 | 6.32 | 5.84 |
| Philip Humber |   | mr | 25 | .885 | 34 | .206 | 29 | .580 | 30 | .600 | 7.7 | 5.9 | 5.32 | 6.11 |
| Tommy Hunter |   | sp | 21 | 1.144 | 46 | .413 | 43 | .683 | 44 | .698 | 17.7 | 13.7 | 13.04 | 12.66 |
| Eric Hurley |   | sp | 22 | .852 | 79 | .266 | 59 | .551 | 60 | .561 | 16.2 | 5.9 | 5.33 | 5.19 |
| Kei Igawa* |   | sp | 28 | 1.281 | 24 | .542 | 17 | .708 | 17 | .708 | 8.8 | 19.7 | 17.74 | 17.14 |
| Jason Isringhausen |   | cl | 35 | .811 | 132 | .326 | 97 | .485 | 102 | .510 | 30.0 | 6.2 | 5.69 | 5.84 |
| Edwin Jackson |   | sp | 24 | .796 | 582 | .302 | 391 | .494 | 393 | .496 | 106.3 | 5.2 | 4.70 | 4.99 |
| Zach Jackson* |   | sp | 25 | .788 | 199 | .312 | 120 | .469 | 123 | .480 | 34.1 | 5.2 | 4.73 | 5.00 |
| Chuck James* |   | sp | 26 | 1.062 | 91 | .286 | 95 | .651 | 98 | .671 | 33.8 | 10.3 | 9.24 | 8.81 |
| Bobby Jenks | OTR | cl | 27 | .620 | 184 | .261 | 91 | .374 | 92 | .379 | 20.2 | 3.0 | 2.65 | 2.43 |
| Jason Jennings |   | sp | 29 | .994 | 96 | .281 | 85 | .630 | 86 | .637 | 27.4 | 8.8 | 8.11 | 8.42 |
| Kevin Jepsen |   | mr | 23 | .677 | 25 | .320 | 15 | .417 | 15 | .417 | 3.8 | 4.1 | 3.73 | 3.46 |
| Cesar Jimenez* |   | mr | 23 | .686 | 99 | .303 | 57 | .404 | 58 | .411 | 14.1 | 3.8 | 3.33 | 3.59 |
| Kelvin Jimenez |   | mr | 27 | .910 | 82 | .280 | 65 | .570 | 66 | .579 | 20.2 | 7.5 | 6.83 | 7.03 |
| Ubaldo Jimenez | TON | sp | 24 | .691 | 572 | .299 | 362 | .417 | 372 | .429 | 95.6 | 4.3 | 3.90 | 3.92 |
| Jason Johnson |   | mr | 34 | .861 | 91 | .297 | 70 | .538 | 72 | .554 | 20.0 | 6.1 | 5.52 | 5.32 |
| Jim Johnson | GEO | mr | 25 | .539 | 212 | .255 | 86 | .306 | 89 | .317 | 16.8 | 2.1 | 1.98 | 2.45 |
| Josh Johnson | LON | sp | 24 | .723 | 253 | .332 | 157 | .430 | 158 | .433 | 41.1 | 4.3 | 3.81 | 3.94 |
| Randy Johnson* | ROK | sp | 44 | .728 | 531 | .301 | 343 | .441 | 349 | .449 | 94.9 | 4.6 | 4.18 | 3.69 |
| Todd Jones |   | cl | 40 | .827 | 152 | .296 | 94 | .487 | 98 | .508 | 28.6 | 6.1 | 5.55 | 5.78 |
| Jorge Julio |   | mr | 29 | .756 | 75 | .320 | 63 | .477 | 64 | .485 | 17.1 | 5.2 | 4.62 | 4.52 |
| Jair Jurrjens | WIZ | sp | 22 | .711 | 589 | .301 | 347 | .427 | 351 | .432 | 94.8 | 4.5 | 4.08 | 3.65 |
| Jeff Karstens |   | sp | 25 | .774 | 177 | .277 | 105 | .477 | 105 | .477 | 27.7 | 4.7 | 4.38 | 4.22 |
| Scott Kazmir* | GEO | sp | 24 | .727 | 378 | .265 | 303 | .473 | 307 | .479 | 76.3 | 4.5 | 4.06 | 3.69 |
| Kyle Kendrick |   | sp | 23 | .855 | 560 | .305 | 366 | .507 | 380 | .526 | 119.0 | 6.8 | 6.19 | 6.05 |
| Ian Kennedy |   | sp | 23 | .917 | 135 | .333 | 110 | .567 | 111 | .572 | 36.7 | 8.3 | 7.49 | 6.93 |
| Logan Kensing |   | mr | 25 | .727 | 155 | .277 | 115 | .453 | 119 | .469 | 32.3 | 5.1 | 4.72 | 4.50 |
| Clayton Kershaw* | MUL | sp | 20 | .756 | 306 | .320 | 220 | .468 | 221 | .470 | 58.8 | 4.9 | 4.42 | 4.53 |
| Ray King* |   | mr | 34 | .956 | 26 | .308 | 18 | .545 | 19 | .576 | 6.6 | 9.0 | 8.49 | 8.66 |
| Josh Kinney |   | mr | 29 | .327 | 16 | .188 | 5 | .200 | 5 | .200 | 0.7 | 0.9 | 0.79 | 0.60 |
| Brandon Knight |   | sp | 32 | .723 | 38 | .368 | 22 | .386 | 24 | .421 | 6.9 | 5.3 | 4.65 | 5.70 |
| Masa Kobayashi |   | mr | 34 | .757 | 186 | .306 | 111 | .455 | 112 | .459 | 31.5 | 5.0 | 4.58 | 4.71 |
| Bobby Korecky |   | mr | 28 | .819 | 58 | .293 | 38 | .514 | 38 | .514 | 9.8 | 5.1 | 4.51 | 5.13 |
| Eddie Kunz |   | mr | 22 | 1.357 | 10 | .400 | 10 | .714 | 11 | .786 | 4.3 | 14.5 | 13.07 | 14.88 |
| Hong-Chih Kuo* | Pal | mr | 26 | .566 | 199 | .281 | 110 | .341 | 113 | .350 | 24.7 | 2.8 | 2.50 | 2.05 |
| Hiroki Kuroda | WIZ | sp | 33 | .659 | 598 | .281 | 299 | .385 | 306 | .394 | 78.0 | 3.8 | 3.44 | 3.18 |
| John Lackey | COP | sp | 29 | .749 | 469 | .288 | 309 | .458 | 319 | .473 | 80.5 | 4.5 | 3.99 | 4.10 |
| Aaron Laffey* |   | sp | 23 | .763 | 316 | .294 | 182 | .445 | 191 | .467 | 49.5 | 4.7 | 4.28 | 4.86 |
| Chris Lambert |   | mr | 25 | .925 | 75 | .373 | 56 | .549 | 58 | .569 | 21.1 | 9.1 | 8.28 | 7.37 |
| John Lannan* |   | sp | 23 | .728 | 560 | .266 | 345 | .443 | 352 | .452 | 90.1 | 4.4 | 4.01 | 4.09 |
| Brandon League |   | mr | 25 | .648 | 98 | .265 | 54 | .383 | 57 | .404 | 12.7 | 3.4 | 3.12 | 3.45 |
| Wade LeBlanc* |   | sp | 23 | 1.086 | 68 | .324 | 73 | .702 | 73 | .702 | 25.2 | 11.0 | 9.57 | 9.57 |
| Wil Ledezma* |   | mr | 27 | .727 | 165 | .285 | 119 | .447 | 122 | .459 | 33.6 | 5.2 | 4.67 | 4.41 |
| Cliff Lee* | MID | sp | 29 | .633 | 670 | .301 | 329 | .369 | 334 | .375 | 78.4 | 3.2 | 2.84 | 2.75 |
| Jon Lester* | EDG | sp | 24 | .688 | 632 | .297 | 356 | .407 | 366 | .419 | 89.6 | 3.9 | 3.45 | 3.55 |
| Jensen Lewis |   | cl | 24 | .771 | 200 | .300 | 136 | .466 | 141 | .483 | 38.8 | 5.3 | 4.76 | 4.66 |
| Scott Lewis* |   | sp | 24 | .671 | 72 | .222 | 42 | .433 | 42 | .433 | 9.0 | 3.3 | 3.05 | 3.01 |
| Brad Lidge | Pal | cl | 31 | .565 | 162 | .296 | 103 | .353 | 104 | .356 | 23.0 | 3.0 | 2.69 | 2.45 |
| Jon Lieber |   | mr | 38 | .881 | 159 | .308 | 112 | .549 | 114 | .559 | 32.5 | 6.1 | 5.64 | 5.30 |
| Ted Lilly* | OTR | sp | 32 | .734 | 574 | .270 | 402 | .467 | 409 | .475 | 103.0 | 4.5 | 4.08 | 3.73 |
| Tim Lincecum | WIZ | sp | 24 | .612 | 562 | .304 | 344 | .371 | 350 | .377 | 79.7 | 3.2 | 2.85 | 2.69 |
| Mike Lincoln |   | mr | 33 | .714 | 203 | .276 | 129 | .434 | 132 | .444 | 33.4 | 4.3 | 3.85 | 3.96 |
| Matt Lindstrom |   | mr | 28 | .688 | 174 | .322 | 97 | .396 | 98 | .400 | 25.2 | 4.0 | 3.56 | 3.69 |
| Scott Linebrink | EDG | mr | 31 | .677 | 129 | .256 | 80 | .430 | 80 | .430 | 18.6 | 3.6 | 3.25 | 3.09 |
| Francisco Liriano* | ROK | sp | 24 | .719 | 222 | .302 | 146 | .444 | 147 | .447 | 38.1 | 4.5 | 4.06 | 3.97 |
| Jesse Litsch | EDG | sp | 23 | .721 | 569 | .278 | 322 | .438 | 330 | .449 | 84.6 | 4.3 | 3.89 | 3.71 |
| Wes Littleton |   | mr | 25 | .701 | 54 | .315 | 31 | .387 | 34 | .425 | 8.2 | 4.0 | 3.71 | 4.64 |
| Radhames Liz |   | sp | 25 | .883 | 266 | .312 | 216 | .550 | 219 | .557 | 68.4 | 7.4 | 6.57 | 6.84 |
| Esteban Loaiza |   | mr | 36 | .733 | 96 | .240 | 53 | .457 | 54 | .466 | 14.5 | 4.7 | 4.34 | 3.49 |
| Kameron Loe |   | mr | 26 | .768 | 103 | .320 | 63 | .470 | 63 | .470 | 18.0 | 5.3 | 4.75 | 4.40 |
| Adam Loewen* |   | sp | 24 | .958 | 65 | .308 | 62 | .608 | 62 | .608 | 20.1 | 8.8 | 7.64 | 8.37 |
| Boone Logan* |   | mr | 23 | .891 | 133 | .376 | 108 | .548 | 109 | .553 | 34.9 | 7.4 | 6.68 | 6.24 |
| Kyle Lohse | CCL | sp | 29 | .734 | 650 | .297 | 374 | .446 | 377 | .449 | 100.7 | 4.6 | 4.08 | 3.77 |
| Braden Looper |   | sp | 33 | .764 | 653 | .292 | 384 | .456 | 395 | .469 | 106.5 | 4.8 | 4.33 | 4.31 |
| Aquilino Lopez |   | mr | 33 | .771 | 250 | .308 | 162 | .471 | 164 | .477 | 46.1 | 5.2 | 4.75 | 4.17 |
| Javier Lopez* | OTR | mr | 30 | .699 | 176 | .278 | 106 | .429 | 108 | .437 | 24.3 | 3.7 | 3.31 | 3.73 |
| Shane Loux |   | mr | 28 | .685 | 57 | .263 | 25 | .379 | 27 | .409 | 6.3 | 3.5 | 3.20 | 3.28 |
| Derek Lowe | BON | sp | 35 | .637 | 644 | .280 | 323 | .380 | 324 | .381 | 77.7 | 3.3 | 2.98 | 2.72 |
| Mark Lowe |   | mr | 25 | .838 | 204 | .353 | 151 | .498 | 155 | .512 | 47.3 | 6.5 | 6.01 | 6.10 |
| Devon Lowery |   | mr | 25 | 1.013 | 11 | .364 | 14 | .667 | 14 | .667 | 5.0 | 10.3 | 9.29 | 9.49 |
| Brandon Lyon | Pal | cl | 28 | .792 | 201 | .338 | 127 | .479 | 127 | .479 | 37.8 | 5.6 | 5.16 | 4.86 |
| Mike MacDougal |   | mr | 31 | .697 | 52 | .308 | 32 | .410 | 34 | .436 | 8.2 | 4.3 | 3.90 | 4.45 |
| Greg Maddux | Pal | sp | 42 | .717 | 649 | .282 | 342 | .425 | 348 | .433 | 93.0 | 4.3 | 3.88 | 3.55 |
| Warner Madrigal |   | mr | 24 | .750 | 114 | .281 | 72 | .468 | 72 | .468 | 19.1 | 4.7 | 4.29 | 4.13 |
| Ryan Madson | CCL | mr | 27 | .675 | 243 | .300 | 138 | .406 | 139 | .409 | 35.3 | 3.9 | 3.46 | 3.20 |
| Ron Mahay* |   | mr | 37 | .695 | 193 | .285 | 118 | .424 | 119 | .428 | 30.1 | 4.2 | 3.78 | 3.98 |
| Paul Maholm* | MAD | sp | 26 | .724 | 621 | .290 | 370 | .434 | 379 | .444 | 94.2 | 4.1 | 3.70 | 3.84 |
| John Maine | BT | sp | 27 | .694 | 399 | .266 | 261 | .429 | 265 | .436 | 66.9 | 4.2 | 3.87 | 3.81 |
| Gary Majewski |   | mr | 28 | .963 | 141 | .390 | 107 | .557 | 110 | .573 | 38.1 | 8.7 | 7.72 | 8.04 |
| Charlie Manning* |   | mr | 29 | .782 | 113 | .239 | 98 | .519 | 98 | .519 | 25.9 | 5.5 | 4.99 | 5.04 |
| Shaun Marcum | COP | sp | 26 | .681 | 428 | .245 | 270 | .429 | 278 | .441 | 66.2 | 3.9 | 3.54 | 3.32 |
| Carlos Marmol | WIZ | mr | 25 | .508 | 177 | .169 | 117 | .336 | 123 | .353 | 22.1 | 2.3 | 2.05 | 1.86 |
| Jason Marquis | CCL | sp | 29 | .746 | 554 | .283 | 329 | .446 | 337 | .457 | 90.7 | 4.8 | 4.40 | 4.35 |
| Sean Marshall* | LON | mr | 25 | .741 | 185 | .276 | 127 | .455 | 131 | .470 | 35.0 | 4.8 | 4.34 | 3.82 |
| Damaso Marte* | WIZ | mr | 33 | .608 | 168 | .280 | 102 | .375 | 104 | .382 | 24.0 | 3.3 | 2.99 | 2.90 |
| Pedro Martinez |   | sp | 36 | .853 | 337 | .320 | 255 | .517 | 261 | .529 | 80.7 | 6.7 | 6.00 | 5.80 |
| Shairon Martis |   | sp | 21 | .820 | 52 | .250 | 51 | .554 | 51 | .554 | 13.9 | 6.0 | 5.46 | 4.98 |
| Nick Masset | GEO | mr | 26 | .817 | 193 | .332 | 133 | .491 | 135 | .498 | 36.5 | 5.3 | 4.77 | 5.27 |
| Justin Masterson | OTR | mr | 23 | .674 | 239 | .243 | 152 | .416 | 160 | .438 | 35.1 | 3.6 | 3.22 | 3.51 |
| Tom Mastny |   | mr | 27 | .981 | 64 | .344 | 63 | .630 | 63 | .630 | 21.6 | 9.6 | 8.75 | 8.39 |
| Doug Mathis |   | sp | 25 | 1.037 | 86 | .395 | 70 | .625 | 70 | .625 | 24.2 | 9.7 | 8.77 | 9.60 |
| Osiris Matos |   | mr | 23 | .931 | 69 | .333 | 56 | .571 | 57 | .582 | 18.7 | 8.0 | 7.34 | 6.06 |
| Daisuke Matsuzaka | OTR | sp | 27 | .645 | 449 | .258 | 291 | .406 | 298 | .416 | 69.1 | 3.7 | 3.34 | 3.36 |
| Brandon McCarthy | EDG | sp | 24 | .739 | 71 | .239 | 43 | .462 | 44 | .473 | 11.6 | 4.7 | 4.27 | 3.87 |
| Kyle McClellan | MAD | mr | 24 | .727 | 231 | .312 | 141 | .431 | 145 | .443 | 38.2 | 4.5 | 4.09 | 4.24 |
| Seth McClung | EDG | mr | 27 | .714 | 297 | .279 | 197 | .432 | 204 | .447 | 51.6 | 4.4 | 3.97 | 4.13 |
| Bob McCrory |   | mr | 26 | .907 | 24 | .417 | 19 | .514 | 19 | .514 | 6.9 | 9.8 | 8.79 | 10.26 |
| James McDonald |   | mr | 23 | .534 | 21 | .238 | 7 | .292 | 7 | .292 | 1.7 | 2.5 | 2.29 | 1.74 |
| Dustin McGowan |   | sp | 26 | .739 | 337 | .315 | 208 | .439 | 213 | .449 | 58.8 | 4.8 | 4.28 | 4.13 |
| Gil Meche | CRH | sp | 29 | .706 | 611 | .303 | 386 | .436 | 386 | .436 | 100.1 | 4.3 | 3.85 | 3.64 |
| Brandon Medders |   | mr | 28 | .720 | 65 | .231 | 38 | .432 | 40 | .455 | 10.8 | 4.9 | 4.46 | 4.13 |
| Evan Meek |   | mr | 25 | .922 | 38 | .211 | 36 | .590 | 37 | .607 | 10.0 | 6.7 | 6.21 | 6.46 |
| Jon Meloan |   | mr | 23 | .167 | 3 | .000 | 1 | .167 | 1 | .167 | 0.0 | 0.0 | 0.00 | 0.31 |
| Luis Mendoza |   | mr | 24 | .928 | 243 | .370 | 173 | .547 | 179 | .566 | 61.7 | 8.6 | 7.89 | 7.53 |
| Kent Mercker* |   | mr | 40 | .756 | 43 | .279 | 27 | .466 | 27 | .466 | 6.3 | 4.1 | 3.71 | 4.42 |
| Cla Meredith |   | mr | 25 | .736 | 222 | .329 | 130 | .430 | 131 | .434 | 36.3 | 4.6 | 4.18 | 4.52 |
| Randy Messenger |   | mr | 26 | .798 | 43 | .349 | 26 | .456 | 27 | .474 | 8.1 | 5.8 | 5.20 | 5.78 |
| Dan Meyer* |   | mr | 26 | .961 | 91 | .319 | 81 | .614 | 82 | .621 | 26.3 | 8.5 | 7.71 | 7.10 |
| Kam Mickolio |   | mr | 24 | .743 | 24 | .333 | 16 | .444 | 16 | .444 | 4.9 | 5.5 | 5.14 | 3.81 |
| Jose Mijares* |   | mr | 23 | .206 | 29 | .103 | 4 | .118 | 4 | .118 | 0.4 | 0.3 | 0.28 | 0.19 |
| Andrew Miller* | GEO | sp | 23 | .798 | 336 | .336 | 232 | .472 | 236 | .480 | 70.4 | 5.9 | 5.31 | 5.04 |
| Jim Miller |   | mr | 26 | .750 | 25 | .360 | 16 | .410 | 17 | .436 | 5.4 | 6.1 | 5.74 | 4.99 |
| Justin Miller |   | mr | 30 | .763 | 132 | .318 | 95 | .470 | 98 | .485 | 26.6 | 5.3 | 4.62 | 4.21 |
| Trever Miller* |   | mr | 35 | .687 | 117 | .316 | 76 | .406 | 80 | .428 | 18.9 | 3.9 | 3.53 | 3.73 |
| Kevin Millwood |   | sp | 33 | .823 | 569 | .355 | 375 | .489 | 381 | .497 | 121.4 | 6.5 | 5.83 | 5.54 |
| Zach Miner | GEO | mr | 26 | .743 | 385 | .281 | 229 | .450 | 235 | .462 | 62.4 | 4.8 | 4.28 | 4.12 |
| Pat Misch* |   | mr | 26 | .785 | 163 | .276 | 109 | .474 | 112 | .487 | 32.7 | 5.6 | 5.06 | 4.88 |
| Garrett Mock | CCL | mr | 25 | .709 | 107 | .308 | 81 | .450 | 81 | .450 | 20.3 | 4.4 | 4.01 | 4.00 |
| Brian Moehler |   | sp | 36 | .772 | 508 | .287 | 305 | .469 | 309 | .475 | 89.3 | 5.3 | 4.82 | 4.31 |
| Franklin Morales* |   | sp | 22 | .869 | 91 | .286 | 64 | .533 | 65 | .542 | 20.5 | 7.3 | 6.55 | 5.58 |
| Juan Morillo |   | mr | 24 | .750 | 4 | .250 | 2 | .500 | 2 | .500 | 0.5 | 4.5 | 4.05 | 1.95 |
| Matt Morris |   | sp | 33 | 1.126 | 94 | .372 | 80 | .678 | 82 | .695 | 30.0 | 11.1 | 10.89 | 10.53 |
| Brandon Morrow | CRH | mr | 23 | .611 | 146 | .205 | 110 | .415 | 110 | .415 | 23.2 | 3.2 | 2.91 | 2.84 |
| Charlie Morton | LON | sp | 24 | .816 | 245 | .290 | 174 | .504 | 176 | .510 | 52.4 | 6.3 | 5.69 | 5.21 |
| Dustin Moseley |   | sp | 26 | .883 | 172 | .372 | 124 | .523 | 126 | .532 | 41.8 | 7.5 | 6.73 | 6.74 |
| Guillermo Mota |   | mr | 34 | .725 | 159 | .283 | 112 | .459 | 112 | .459 | 28.6 | 4.5 | 4.06 | 4.14 |
| Jason Motte |   | mr | 26 | .344 | 21 | .238 | 8 | .200 | 8 | .200 | 1.1 | 0.9 | 0.81 | 0.89 |
| Jamie Moyer* | LON | sp | 45 | .731 | 625 | .286 | 369 | .439 | 380 | .452 | 99.6 | 4.5 | 4.11 | 4.03 |
| Peter Moylan |   | mr | 29 | .628 | 17 | .235 | 9 | .360 | 10 | .400 | 2.5 | 3.8 | 3.62 | 3.51 |
| Edward Mujica |   | mr | 24 | .849 | 125 | .328 | 88 | .524 | 89 | .530 | 25.4 | 5.9 | 5.33 | 4.82 |
| Mark Mulder* |   | mr | 30 | 1.083 | 7 | .571 | 6 | .500 | 7 | .583 | 3.4 | 18.3 | 16.50 | 18.81 |
| Carlos Muniz |   | mr | 27 | .786 | 71 | .282 | 48 | .480 | 50 | .500 | 14.0 | 5.6 | 4.87 | 4.74 |
| A.J. Murray* |   | sp | 26 | .795 | 30 | .400 | 17 | .447 | 17 | .447 | 5.4 | 6.1 | 5.75 | 6.43 |
| Neal Musser* |   | mr | 27 | .333 | 2 | .000 | 1 | .333 | 1 | .333 | 0.0 | 0.0 | 0.00 | 1.26 |
| Mike Mussina | MID | sp | 39 | .721 | 613 | .321 | 347 | .424 | 355 | .433 | 91.4 | 4.1 | 3.70 | 3.61 |
| Brett Myers | CRH | sp | 27 | .791 | 554 | .303 | 406 | .497 | 412 | .504 | 112.0 | 5.3 | 4.77 | 4.53 |
| Joe Nathan | WIZ | cl | 33 | .521 | 162 | .235 | 85 | .326 | 87 | .333 | 15.9 | 2.1 | 1.91 | 1.67 |
| Joe Nelson | CCL | mr | 33 | .616 | 141 | .262 | 88 | .383 | 90 | .391 | 20.1 | 3.3 | 3.02 | 2.80 |
| Pat Neshek | BON | mr | 27 | .751 | 35 | .286 | 27 | .482 | 27 | .482 | 7.1 | 4.8 | 4.31 | 3.29 |
| Josh Newman* |   | mr | 26 | 1.102 | 58 | .362 | 56 | .667 | 58 | .690 | 21.3 | 12.3 | 11.03 | 11.44 |
| Jeff Niemann |   | mr | 25 | .857 | 50 | .300 | 40 | .526 | 41 | .539 | 12.0 | 6.3 | 6.07 | 5.93 |
| Jonathon Niese* |   | sp | 21 | .945 | 48 | .375 | 40 | .580 | 40 | .580 | 13.5 | 8.7 | 7.83 | 7.71 |
| Fernando Nieve |   | mr | 25 | .941 | 33 | .455 | 28 | .571 | 28 | .571 | 9.7 | 8.5 | 7.40 | 7.62 |
| Dustin Nippert |   | mr | 27 | .873 | 238 | .345 | 183 | .537 | 184 | .540 | 58.6 | 7.3 | 6.62 | 6.47 |
| Ricky Nolasco | CCL | sp | 25 | .688 | 606 | .271 | 372 | .429 | 378 | .435 | 90.9 | 3.8 | 3.47 | 3.03 |
| Hideo Nomo |   | mr | 39 | 1.519 | 17 | .412 | 26 | .963 | 26 | .963 | 12.5 | 25.9 | 23.34 | 21.77 |
| Leo Nunez | ROK | mr | 24 | .665 | 158 | .272 | 78 | .380 | 82 | .400 | 20.0 | 3.7 | 3.34 | 3.20 |
| Vladimir Nunez |   | mr | 33 | .714 | 102 | .314 | 63 | .432 | 64 | .438 | 16.3 | 4.4 | 4.03 | 3.77 |
| Mike O'Connor* |   | mr | 27 | 1.096 | 30 | .267 | 32 | .667 | 32 | .667 | 11.3 | 11.3 | 10.21 | 11.25 |
| Darren O'Day | MID | mr | 25 | .719 | 145 | .324 | 78 | .402 | 82 | .423 | 22.3 | 4.6 | 4.16 | 4.20 |
| Eric O'Flaherty* |   | mr | 23 | 1.324 | 30 | .467 | 32 | .762 | 34 | .810 | 15.6 | 20.0 | 18.91 | 17.12 |
| Ross Ohlendorf |   | mr | 25 | .898 | 209 | .364 | 165 | .550 | 166 | .553 | 52.7 | 7.5 | 6.81 | 7.16 |
| Will Ohman* | MAD | mr | 30 | .640 | 169 | .284 | 97 | .391 | 98 | .395 | 22.8 | 3.4 | 3.15 | 2.87 |
| Hideki Okajima* | COP | mr | 32 | .612 | 168 | .256 | 99 | .384 | 100 | .388 | 23.0 | 3.3 | 3.00 | 2.82 |
| Darren Oliver* | GEO | mr | 37 | .682 | 218 | .284 | 116 | .399 | 120 | .412 | 29.3 | 3.7 | 3.30 | 3.07 |
| Scott Olsen* |   | sp | 24 | .751 | 640 | .258 | 406 | .475 | 409 | .478 | 104.2 | 4.6 | 4.19 | 3.96 |
| Garrett Olson* |   | sp | 24 | .861 | 451 | .335 | 320 | .515 | 328 | .528 | 105.3 | 7.2 | 6.43 | 6.40 |
| Franquelis Osoria |   | mr | 26 | .927 | 219 | .352 | 155 | .562 | 159 | .576 | 49.2 | 7.2 | 6.57 | 6.67 |
| Roy Oswalt | BT | sp | 30 | .692 | 617 | .285 | 356 | .413 | 366 | .425 | 92.2 | 4.0 | 3.58 | 3.40 |
| Josh Outman* |   | sp | 23 | .860 | 86 | .384 | 58 | .500 | 60 | .517 | 19.1 | 6.9 | 6.01 | 5.49 |
| Micah Owings | MUL | sp | 25 | .754 | 312 | .288 | 210 | .451 | 222 | .476 | 61.1 | 5.3 | 4.73 | 4.66 |
| Vicente Padilla |   | sp | 30 | .798 | 524 | .303 | 366 | .483 | 381 | .503 | 103.8 | 5.4 | 4.92 | 5.20 |
| Matt Palmer |   | sp | 29 | .936 | 48 | .333 | 36 | .537 | 38 | .567 | 12.2 | 8.9 | 7.78 | 9.37 |
| Jonathan Papelbon | BON | cl | 27 | .561 | 184 | .293 | 90 | .330 | 90 | .330 | 20.2 | 2.6 | 2.36 | 1.92 |
| Mike Parisi |   | mr | 25 | .980 | 91 | .385 | 70 | .579 | 70 | .579 | 25.5 | 9.8 | 8.97 | 8.44 |
| Chan Ho Park |   | mr | 35 | .749 | 281 | .302 | 188 | .456 | 192 | .466 | 50.1 | 4.7 | 4.26 | 4.34 |
| Bobby Parnell |   | mr | 23 | .440 | 14 | .214 | 5 | .263 | 5 | .263 | 0.7 | 1.3 | 1.20 | 1.59 |
| Chad Paronto |   | mr | 32 | .904 | 33 | .273 | 24 | .585 | 24 | .585 | 5.6 | 4.9 | 4.40 | 4.49 |
| James Parr |   | sp | 22 | .952 | 75 | .333 | 62 | .608 | 62 | .608 | 19.2 | 7.7 | 6.95 | 6.53 |
| Manny Parra* |   | sp | 25 | .766 | 499 | .327 | 344 | .464 | 346 | .467 | 94.9 | 5.1 | 4.63 | 4.89 |
| John Parrish* |   | mr | 30 | .800 | 138 | .304 | 89 | .497 | 89 | .497 | 24.4 | 5.3 | 4.67 | 4.82 |
| Scott Patterson |   | mr | 29 | .614 | 9 | .222 | 10 | .455 | 10 | .455 | 2.1 | 4.1 | 3.67 | 2.97 |
| David Pauley |   | mr | 25 | 1.033 | 48 | .438 | 41 | .612 | 42 | .627 | 16.9 | 12.0 | 11.12 | 10.16 |
| Carl Pavano |   | sp | 32 | .842 | 120 | .300 | 74 | .481 | 78 | .506 | 24.8 | 6.6 | 5.84 | 5.60 |
| Jake Peavy | MUL | sp | 27 | .645 | 462 | .279 | 279 | .394 | 284 | .401 | 66.6 | 3.5 | 3.11 | 3.12 |
| Jailen Peguero |   | mr | 27 | .753 | 28 | .321 | 16 | .421 | 17 | .447 | 4.0 | 4.0 | 3.47 | 4.01 |
| Mike Pelfrey |   | sp | 24 | .734 | 652 | .302 | 362 | .425 | 375 | .441 | 96.9 | 4.4 | 3.91 | 4.04 |
| Tony Pena |   | mr | 26 | .748 | 236 | .318 | 138 | .441 | 141 | .450 | 39.1 | 4.8 | 4.36 | 3.79 |
| Brad Penny |   | sp | 30 | .843 | 317 | .312 | 213 | .500 | 216 | .507 | 64.5 | 6.2 | 5.52 | 5.82 |
| Joel Peralta | MID | mr | 32 | .867 | 155 | .265 | 125 | .558 | 127 | .567 | 35.0 | 6.0 | 5.38 | 5.38 |
| Troy Percival |   | cl | 38 | .700 | 119 | .168 | 93 | .479 | 94 | .485 | 22.2 | 4.3 | 3.95 | 3.50 |
| Chris Perez | LON | mr | 22 | .751 | 107 | .271 | 86 | .486 | 87 | .492 | 20.4 | 4.3 | 3.96 | 3.83 |
| Odalis Perez* |   | sp | 31 | .825 | 507 | .316 | 356 | .501 | 364 | .512 | 104.9 | 5.8 | 5.32 | 5.07 |
| Oliver Perez* | WIZ | sp | 26 | .725 | 527 | .271 | 382 | .451 | 393 | .464 | 100.4 | 4.7 | 4.19 | 4.21 |
| Rafael Perez* | BT | mr | 26 | .649 | 194 | .304 | 124 | .396 | 126 | .403 | 27.5 | 3.2 | 2.91 | 3.14 |
| Glen Perkins* | BON | sp | 25 | .837 | 520 | .304 | 339 | .513 | 342 | .517 | 100.6 | 6.0 | 5.40 | 5.30 |
| Yusmeiro Petit | WIZ | mr | 23 | .704 | 160 | .206 | 105 | .459 | 106 | .463 | 25.0 | 3.9 | 3.59 | 3.08 |
| Andy Pettitte* |   | sp | 36 | .760 | 642 | .333 | 394 | .447 | 401 | .455 | 114.9 | 5.1 | 4.56 | 4.45 |
| Adam Pettyjohn* |   | mr | 31 | 1.365 | 20 | .450 | 21 | .808 | 22 | .846 | 10.5 | 23.6 | 21.28 | 21.60 |
| Carmen Pignatiello* |   | mr | 25 | 1.464 | 4 | .500 | 5 | .714 | 6 | .857 | 2.7 | 36.5 | 32.81 | 37.18 |
| Joel Pineiro | CCL | sp | 29 | .847 | 505 | .313 | 338 | .524 | 340 | .527 | 98.9 | 6.0 | 5.39 | 5.05 |
| Renyel Pinto* |   | mr | 25 | .707 | 176 | .244 | 123 | .433 | 127 | .447 | 30.9 | 4.2 | 3.87 | 4.24 |
| Sidney Ponson |   | sp | 31 | .833 | 485 | .322 | 302 | .493 | 309 | .505 | 91.1 | 6.0 | 5.44 | 5.63 |
| David Price* |   | mr | 22 | .501 | 39 | .205 | 17 | .298 | 18 | .316 | 3.4 | 2.1 | 1.96 | 1.86 |
| Scott Proctor |   | mr | 31 | .833 | 107 | .318 | 99 | .538 | 99 | .538 | 28.9 | 6.5 | 6.05 | 5.67 |
| David Purcey* |   | sp | 26 | .787 | 189 | .307 | 139 | .481 | 143 | .495 | 39.3 | 5.4 | 4.90 | 4.96 |
| J.J. Putz | MID | cl | 31 | .749 | 121 | .347 | 98 | .464 | 100 | .474 | 26.4 | 5.1 | 4.61 | 4.82 |
| Chad Qualls | BON | mr | 29 | .601 | 204 | .279 | 106 | .353 | 109 | .363 | 22.6 | 2.6 | 2.48 | 2.40 |
| Edwar Ramirez | EDG | mr | 27 | .685 | 136 | .272 | 102 | .438 | 105 | .451 | 24.4 | 3.9 | 3.57 | 3.42 |
| Elizardo Ramirez |   | mr | 25 | 1.329 | 14 | .500 | 14 | .737 | 15 | .789 | 7.4 | 25.0 | 22.47 | 24.96 |
| Horacio Ramirez* |   | mr | 28 | .718 | 143 | .308 | 67 | .399 | 69 | .411 | 21.4 | 5.1 | 4.64 | 4.13 |
| Ramon Ramirez | LON | mr | 26 | .590 | 192 | .286 | 105 | .356 | 105 | .356 | 23.2 | 2.9 | 2.63 | 2.53 |
| Ramon Ramirez |   | sp | 25 | .556 | 69 | .203 | 37 | .352 | 38 | .362 | 6.6 | 2.2 | 1.98 | 2.48 |
| Clay Rapada* |   | mr | 27 | .660 | 64 | .297 | 37 | .394 | 38 | .404 | 9.0 | 3.8 | 3.40 | 3.87 |
| Darrell Rasner |   | sp | 27 | .807 | 388 | .312 | 248 | .483 | 253 | .493 | 72.8 | 5.7 | 5.20 | 5.23 |
| Jon Rauch |   | mr | 29 | .742 | 202 | .287 | 137 | .464 | 137 | .464 | 35.9 | 4.5 | 4.06 | 3.48 |
| Tim Redding |   | sp | 30 | .788 | 572 | .294 | 383 | .484 | 390 | .493 | 107.6 | 5.3 | 4.79 | 4.80 |
| Mark Redman* |   | sp | 34 | .905 | 167 | .323 | 115 | .545 | 116 | .550 | 36.5 | 7.1 | 6.53 | 6.31 |
| Steven Register |   | mr | 25 | 1.054 | 31 | .290 | 34 | .694 | 34 | .694 | 11.6 | 10.4 | 9.37 | 8.89 |
| Chad Reineke |   | sp | 26 | .681 | 52 | .250 | 34 | .436 | 34 | .436 | 8.3 | 4.2 | 3.74 | 3.48 |
| Chris Resop |   | mr | 25 | .768 | 55 | .255 | 38 | .463 | 40 | .488 | 10.8 | 5.3 | 4.75 | 4.19 |
| Al Reyes |   | mr | 38 | .719 | 64 | .297 | 42 | .438 | 43 | .448 | 11.4 | 4.7 | 4.07 | 3.86 |
| Anthony Reyes |   | sp | 26 | .694 | 158 | .272 | 86 | .424 | 87 | .429 | 21.7 | 4.0 | 3.59 | 3.50 |
| Dennys Reyes* |   | mr | 31 | .658 | 128 | .281 | 75 | .399 | 77 | .410 | 16.9 | 3.2 | 2.95 | 3.14 |
| Jo-Jo Reyes* |   | sp | 23 | .877 | 361 | .321 | 275 | .537 | 278 | .543 | 82.1 | 6.5 | 5.88 | 5.97 |
| Greg Reynolds |   | sp | 22 | .959 | 228 | .303 | 173 | .588 | 177 | .602 | 58.3 | 8.5 | 7.62 | 7.36 |
| Arthur Rhodes* | OTR | mr | 38 | .566 | 90 | .311 | 48 | .329 | 48 | .329 | 10.7 | 2.8 | 2.46 | 2.36 |
| Clayton Richard* |   | sp | 24 | .802 | 168 | .333 | 105 | .488 | 105 | .488 | 32.1 | 6.0 | 5.45 | 5.06 |
| Scott Richmond |   | sp | 28 | .809 | 87 | .345 | 55 | .487 | 57 | .504 | 15.6 | 5.2 | 4.68 | 3.99 |
| Jeff Ridgway* |   | mr | 27 | .709 | 25 | .160 | 18 | .474 | 19 | .500 | 4.1 | 3.9 | 3.48 | 3.03 |
| Juan Rincon |   | mr | 29 | .831 | 180 | .328 | 127 | .500 | 130 | .512 | 38.9 | 6.3 | 5.70 | 5.96 |
| Ricardo Rincon* |   | mr | 38 | .846 | 11 | .273 | 9 | .563 | 9 | .563 | 2.1 | 4.6 | 4.18 | 4.69 |
| Royce Ring* |   | mr | 27 | .921 | 83 | .361 | 60 | .531 | 62 | .549 | 20.5 | 7.7 | 7.44 | 6.61 |
| David Riske |   | mr | 31 | .849 | 135 | .304 | 103 | .534 | 103 | .534 | 30.4 | 6.5 | 5.82 | 5.88 |
| Mariano Rivera | ROK | cl | 38 | .423 | 170 | .218 | 64 | .247 | 66 | .255 | 11.4 | 1.4 | 1.31 | 1.09 |
| Saul Rivera |   | mr | 30 | .687 | 266 | .327 | 146 | .394 | 148 | .399 | 41.8 | 4.5 | 4.03 | 4.11 |
| Connor Robertson |   | mr | 26 | .855 | 26 | .269 | 16 | .500 | 17 | .531 | 5.2 | 6.6 | 5.98 | 4.96 |
| David Robertson |   | mr | 23 | .690 | 77 | .338 | 55 | .420 | 55 | .420 | 14.4 | 4.3 | 3.83 | 4.12 |
| Nate Robertson* |   | sp | 30 | .891 | 563 | .341 | 421 | .553 | 423 | .556 | 127.2 | 6.8 | 6.11 | 6.14 |
| Fernando Rodney | OTR | cl | 31 | .733 | 103 | .301 | 87 | .463 | 90 | .479 | 23.8 | 5.3 | 4.79 | 4.29 |
| Francisco Rodriguez | BON | cl | 26 | .630 | 171 | .292 | 113 | .392 | 115 | .399 | 27.3 | 3.6 | 3.24 | 3.06 |
| Wandy Rodriguez* | BT | sp | 29 | .717 | 393 | .310 | 257 | .438 | 262 | .446 | 67.2 | 4.4 | 3.96 | 3.82 |
| Josh Roenicke |   | mr | 25 | 1.167 | 9 | .667 | 12 | .667 | 13 | .722 | 5.4 | 16.2 | 14.55 | 12.01 |
| Kenny Rogers* |   | sp | 43 | .872 | 598 | .318 | 410 | .524 | 419 | .536 | 124.8 | 6.5 | 5.82 | 5.90 |
| J.C. Romero* |   | mr | 32 | .647 | 155 | .232 | 103 | .404 | 108 | .424 | 25.5 | 3.9 | 3.49 | 3.42 |
| Sergio Romo |   | mr | 25 | .470 | 83 | .157 | 38 | .292 | 41 | .315 | 7.2 | 1.9 | 1.73 | 1.27 |
| Carlos Rosa |   | mr | 23 | .667 | 9 | .333 | 5 | .417 | 5 | .417 | 0.8 | 2.3 | 2.03 | 1.70 |
| Leo Rosales |   | mr | 27 | .762 | 100 | .300 | 63 | .463 | 64 | .471 | 18.1 | 5.4 | 4.88 | 4.51 |
| Ryan Rowland-Smith* | CRH | mr | 25 | .729 | 366 | .276 | 230 | .455 | 232 | .458 | 59.6 | 4.5 | 4.08 | 4.05 |
| Rich Rundles* |   | mr | 27 | .679 | 13 | .385 | 9 | .409 | 9 | .409 | 2.3 | 4.2 | 3.76 | 4.20 |
| Josh Rupe |   | mr | 25 | .819 | 275 | .309 | 189 | .482 | 199 | .508 | 52.7 | 5.4 | 4.78 | 5.30 |
| Glendon Rusch* |   | mr | 33 | .784 | 277 | .303 | 176 | .480 | 176 | .480 | 51.3 | 5.5 | 4.97 | 4.31 |
| Adam Russell |   | mr | 25 | .741 | 83 | .349 | 49 | .415 | 51 | .432 | 14.7 | 5.1 | 4.59 | 4.63 |
| B.J. Ryan* | CRH | cl | 32 | .650 | 155 | .271 | 99 | .398 | 103 | .414 | 24.2 | 3.7 | 3.38 | 3.20 |
| Jae Kuk Ryu |   | mr | 25 | .200 | 3 | .000 | 1 | .200 | 1 | .200 | 0.1 | 0.4 | 0.32 | 0.57 |
| Kirk Saarloos |   | mr | 29 | .770 | 100 | .350 | 51 | .432 | 51 | .432 | 15.9 | 5.4 | 4.89 | 5.13 |
| C.C. Sabathia* | CRH | sp | 27 | .625 | 687 | .297 | 379 | .370 | 386 | .377 | 91.3 | 3.3 | 2.92 | 2.78 |
| Billy Sadler |   | mr | 26 | .727 | 114 | .246 | 86 | .437 | 94 | .477 | 22.6 | 4.6 | 4.13 | 4.42 |
| Takashi Saito | Pal | cl | 38 | .594 | 118 | .331 | 69 | .350 | 71 | .360 | 16.3 | 3.1 | 2.81 | 2.57 |
| Juan Salas |   | mr | 29 | .681 | 15 | .333 | 12 | .444 | 12 | .444 | 3.0 | 4.5 | 3.85 | 3.15 |
| Marino Salas |   | mr | 26 | 1.043 | 59 | .356 | 54 | .614 | 56 | .636 | 19.2 | 10.4 | 9.14 | 10.53 |
| Jeff Samardzija |   | mr | 23 | .599 | 83 | .289 | 44 | .355 | 45 | .363 | 11.4 | 3.6 | 3.34 | 3.08 |
| Chris Sampson | MUL | mr | 30 | .697 | 383 | .287 | 198 | .414 | 201 | .421 | 48.6 | 3.7 | 3.35 | 3.21 |
| Brian Sanches |   | mr | 29 | .918 | 36 | .389 | 29 | .537 | 30 | .556 | 9.9 | 7.8 | 7.25 | 8.15 |
| Anibal Sanchez | MAD | sp | 24 | .788 | 151 | .311 | 112 | .465 | 118 | .490 | 35.6 | 6.2 | 5.58 | 5.40 |
| Duaner Sanchez | BT | mr | 28 | .681 | 178 | .270 | 106 | .417 | 109 | .429 | 27.8 | 4.2 | 3.86 | 3.71 |
| Humberto Sanchez |   | mr | 25 | .542 | 5 | .200 | 3 | .375 | 3 | .375 | 0.4 | 1.7 | 1.54 | 3.21 |
| Jonathan Sanchez* | MAD | sp | 25 | .746 | 442 | .317 | 316 | .455 | 323 | .465 | 88.4 | 5.0 | 4.53 | 4.31 |
| Romulo Sanchez |   | mr | 24 | .764 | 47 | .298 | 25 | .439 | 26 | .456 | 6.5 | 4.4 | 3.96 | 4.30 |
| Ervin Santana | BON | sp | 25 | .651 | 605 | .289 | 354 | .395 | 362 | .404 | 88.8 | 3.6 | 3.28 | 3.00 |
| Johan Santana* | ROK | sp | 29 | .648 | 668 | .274 | 384 | .398 | 388 | .402 | 91.7 | 3.5 | 3.17 | 2.93 |
| Dennis Sarfate |   | mr | 27 | .707 | 196 | .276 | 159 | .443 | 166 | .462 | 39.5 | 4.4 | 4.01 | 4.65 |
| Joe Saunders* | MID | sp | 27 | .691 | 624 | .266 | 337 | .418 | 343 | .425 | 81.6 | 3.7 | 3.34 | 3.49 |
| Max Scherzer | LON | mr | 23 | .649 | 140 | .307 | 89 | .376 | 94 | .397 | 22.3 | 3.6 | 3.22 | 3.45 |
| Scott Schoeneweis* |   | mr | 34 | .751 | 175 | .274 | 110 | .453 | 114 | .469 | 29.1 | 4.7 | 4.16 | 4.28 |
| Chris Schroder |   | mr | 29 | 1.062 | 16 | .250 | 18 | .667 | 18 | .667 | 6.3 | 11.3 | 10.14 | 11.40 |
| Rudy Seanez | TON | mr | 39 | .682 | 131 | .275 | 79 | .418 | 80 | .423 | 20.4 | 4.2 | 3.82 | 3.64 |
| Bobby Seay* |   | mr | 30 | .741 | 157 | .350 | 107 | .435 | 109 | .443 | 30.6 | 5.0 | 4.40 | 4.29 |
| Alex Serrano |   | mr | 27 | .750 | 3 | .333 | 2 | .500 | 2 | .500 | 0.5 | 4.5 | 4.05 | 1.95 |
| Ben Sheets | CRH | sp | 29 | .674 | 589 | .278 | 340 | .419 | 341 | .420 | 83.9 | 3.8 | 3.43 | 2.89 |
| Steven Shell | CRH | mr | 25 | .603 | 131 | .221 | 76 | .382 | 78 | .392 | 16.3 | 3.0 | 2.64 | 2.58 |
| George Sherrill* | ROK | cl | 31 | .708 | 141 | .291 | 107 | .448 | 108 | .452 | 27.4 | 4.6 | 4.16 | 4.18 |
| James Shields | BON | sp | 26 | .708 | 641 | .287 | 375 | .428 | 387 | .441 | 94.4 | 4.0 | 3.56 | 3.41 |
| Scot Shields | ROK | mr | 32 | .669 | 169 | .296 | 111 | .411 | 113 | .419 | 26.3 | 3.6 | 3.37 | 3.72 |
| Brian Shouse* | OTR | mr | 39 | .656 | 160 | .256 | 85 | .401 | 85 | .401 | 19.5 | 3.3 | 3.08 | 2.87 |
| Carlos Silva |   | sp | 29 | .868 | 564 | .342 | 357 | .518 | 361 | .524 | 114.1 | 6.7 | 6.03 | 5.93 |
| Alfredo Simon |   | mr | 27 | .950 | 43 | .279 | 35 | .593 | 37 | .627 | 11.3 | 7.6 | 7.04 | 6.45 |
| Doug Slaten* |   | mr | 28 | .790 | 105 | .276 | 70 | .476 | 74 | .503 | 19.7 | 5.3 | 4.92 | 4.86 |
| Brian Slocum |   | mr | 27 | 1.754 | 11 | .545 | 15 | 1.000 | 16 | 1.067 | 9.5 | 42.6 | 38.35 | 38.27 |
| Kevin Slowey |   | sp | 24 | .728 | 480 | .290 | 295 | .452 | 299 | .458 | 75.9 | 4.3 | 3.83 | 3.48 |
| Chris Smith |   | mr | 27 | .904 | 52 | .231 | 47 | .603 | 47 | .603 | 13.2 | 6.6 | 5.83 | 5.53 |
| Greg Smith* |   | sp | 24 | .729 | 578 | .256 | 367 | .459 | 370 | .463 | 92.3 | 4.4 | 3.93 | 3.84 |
| Joe Smith | MAD | mr | 24 | .658 | 180 | .261 | 109 | .402 | 113 | .417 | 26.6 | 3.7 | 3.40 | 3.23 |
| John Smoltz |   | sp | 41 | .649 | 71 | .324 | 48 | .410 | 48 | .410 | 11.9 | 3.8 | 3.45 | 2.77 |
| Ian Snell |   | sp | 26 | .859 | 522 | .351 | 403 | .526 | 405 | .529 | 125.5 | 6.8 | 6.19 | 6.11 |
| Kyle Snyder |   | mr | 30 | 1.333 | 5 | .200 | 7 | .778 | 7 | .778 | 2.7 | 14.5 | 13.05 | 13.35 |
| Andy Sonnanstine | EDG | sp | 25 | .758 | 632 | .302 | 378 | .462 | 383 | .468 | 102.9 | 4.8 | 4.31 | 3.92 |
| Joakim Soria | BON | cl | 24 | .503 | 164 | .207 | 78 | .300 | 84 | .323 | 15.2 | 2.0 | 1.83 | 1.72 |
| Rafael Soriano | GEO | mr | 28 | .575 | 30 | .200 | 22 | .386 | 23 | .404 | 4.1 | 2.6 | 2.38 | 2.27 |
| Jorge Sosa |   | mr | 31 | .921 | 80 | .325 | 60 | .561 | 60 | .561 | 19.1 | 7.6 | 7.14 | 6.95 |
| Jeremy Sowers* |   | sp | 25 | .827 | 409 | .301 | 272 | .510 | 275 | .516 | 78.0 | 5.7 | 5.22 | 5.17 |
| Justin Speier |   | mr | 34 | .839 | 201 | .269 | 159 | .521 | 165 | .541 | 46.8 | 6.1 | 5.57 | 5.17 |
| Ryan Speier | MUL | mr | 28 | .714 | 159 | .308 | 89 | .410 | 93 | .429 | 23.6 | 4.1 | 3.75 | 4.05 |
| Levale Speigner |   | mr | 27 | 1.087 | 32 | .375 | 24 | .571 | 26 | .619 | 8.4 | 9.5 | 8.54 | 11.19 |
| Russ Springer | WIZ | mr | 39 | .595 | 137 | .255 | 75 | .366 | 76 | .371 | 16.7 | 3.0 | 2.69 | 2.68 |
| Mitch Stetter* |   | mr | 27 | .613 | 53 | .226 | 42 | .385 | 46 | .422 | 9.2 | 3.3 | 2.93 | 3.40 |
| Phil Stockman |   | mr | 28 | .424 | 14 | .143 | 8 | .286 | 9 | .321 | 1.2 | 1.5 | 1.38 | 1.16 |
| Brian Stokes |   | mr | 28 | .748 | 99 | .303 | 62 | .449 | 62 | .449 | 16.8 | 4.6 | 4.08 | 3.99 |
| Huston Street | GEO | cl | 24 | .670 | 184 | .283 | 120 | .418 | 121 | .422 | 28.2 | 3.6 | 3.26 | 2.98 |
| Eric Stults* |   | sp | 28 | .732 | 117 | .274 | 76 | .455 | 77 | .461 | 20.4 | 4.7 | 4.28 | 4.07 |
| Tanyon Sturtze |   | mr | 37 | .472 | 7 | .143 | 3 | .333 | 3 | .333 | 0.5 | 1.9 | 1.74 | 1.08 |
| Jeff Suppan |   | sp | 33 | .844 | 589 | .301 | 403 | .517 | 407 | .522 | 115.6 | 5.9 | 5.27 | 5.58 |
| R.J. Swindle* |   | mr | 24 | 1.140 | 16 | .438 | 17 | .708 | 17 | .708 | 7.1 | 14.8 | 12.35 | 13.63 |
| Mitch Talbot |   | mr | 24 | 1.233 | 34 | .382 | 41 | .759 | 42 | .778 | 16.4 | 15.9 | 13.78 | 14.85 |
| Brian Tallet* | EDG | mr | 30 | .664 | 166 | .289 | 97 | .404 | 98 | .408 | 25.1 | 4.0 | 3.61 | 3.39 |
| Taylor Tankersley* |   | mr | 25 | .995 | 56 | .286 | 54 | .643 | 55 | .655 | 17.5 | 8.7 | 8.00 | 7.76 |
| Jack Taschner* |   | mr | 30 | .812 | 157 | .331 | 110 | .485 | 112 | .493 | 33.8 | 6.1 | 5.71 | 5.56 |
| Ty Taubenheim |   | sp | 25 | .762 | 20 | .350 | 12 | .444 | 12 | .444 | 3.6 | 5.4 | 4.87 | 4.72 |
| Julian Tavarez |   | mr | 35 | .851 | 180 | .378 | 132 | .494 | 135 | .506 | 43.9 | 7.1 | 6.51 | 6.42 |
| Robinson Tejeda | OTR | mr | 26 | .571 | 112 | .205 | 70 | .376 | 71 | .382 | 15.1 | 3.0 | 2.69 | 2.43 |
| Joe Thatcher* |   | mr | 26 | 1.018 | 94 | .404 | 77 | .602 | 77 | .602 | 28.4 | 10.1 | 8.97 | 8.91 |
| Justin Thomas* |   | mr | 24 | 1.103 | 18 | .500 | 13 | .591 | 13 | .591 | 6.0 | 14.8 | 12.19 | 12.01 |
| Brad Thompson |   | mr | 26 | .798 | 214 | .313 | 130 | .476 | 133 | .487 | 36.4 | 5.2 | 4.55 | 4.44 |
| Daryl Thompson |   | sp | 22 | .947 | 52 | .327 | 40 | .580 | 41 | .594 | 13.2 | 8.3 | 7.47 | 8.14 |
| Rich Thompson |   | mr | 23 | 1.100 | 9 | .444 | 8 | .667 | 8 | .667 | 3.5 | 15.8 | 14.26 | 12.01 |
| Matt Thornton* | CRH | mr | 31 | .544 | 165 | .261 | 89 | .332 | 91 | .340 | 18.6 | 2.5 | 2.24 | 2.07 |
| Erick Threets* |   | mr | 26 | .956 | 31 | .323 | 27 | .540 | 30 | .600 | 9.1 | 8.5 | 7.36 | 7.86 |
| Mike Timlin |   | mr | 42 | .891 | 165 | .309 | 125 | .551 | 126 | .555 | 39.9 | 7.2 | 6.55 | 5.85 |
| Brett Tomko |   | sp | 35 | .820 | 229 | .314 | 158 | .515 | 158 | .515 | 46.1 | 5.9 | 5.33 | 4.88 |
| Salomon Torres | MUL | cl | 36 | .680 | 250 | .276 | 136 | .395 | 140 | .407 | 33.1 | 3.6 | 3.36 | 3.70 |
| Billy Traber* |   | mr | 28 | .893 | 57 | .351 | 42 | .525 | 44 | .550 | 14.5 | 7.8 | 7.04 | 7.54 |
| Steve Trachsel |   | sp | 37 | 1.020 | 140 | .307 | 126 | .649 | 127 | .655 | 41.9 | 9.4 | 8.56 | 8.85 |
| Ramon Troncoso |   | mr | 25 | .717 | 105 | .333 | 65 | .406 | 68 | .425 | 17.7 | 4.2 | 3.77 | 3.60 |
| Ryan Tucker |   | mr | 21 | .931 | 117 | .325 | 103 | .579 | 105 | .590 | 33.2 | 8.1 | 7.28 | 7.63 |
| Derrick Turnbow |   | mr | 30 | 1.260 | 24 | .458 | 32 | .727 | 33 | .750 | 13.6 | 19.3 | 17.40 | 18.86 |
| Merkin Valdez |   | mr | 26 | .677 | 46 | .283 | 27 | .391 | 29 | .420 | 7.0 | 3.9 | 3.52 | 3.57 |
| Jose Valverde | WIZ | cl | 28 | .686 | 185 | .281 | 133 | .439 | 135 | .446 | 34.5 | 4.3 | 3.88 | 3.18 |
| John Van Benschoten |   | sp | 28 | 1.147 | 74 | .405 | 87 | .696 | 90 | .720 | 33.7 | 13.2 | 12.24 | 13.13 |
| Rick VandenHurk |   | sp | 23 | .878 | 41 | .463 | 36 | .486 | 38 | .514 | 13.0 | 8.4 | 7.55 | 8.20 |
| Claudio Vargas |   | mr | 30 | .679 | 113 | .257 | 61 | .407 | 63 | .420 | 14.8 | 3.6 | 3.24 | 3.46 |
| Javier Vazquez | Pal | sp | 31 | .755 | 598 | .316 | 418 | .470 | 424 | .476 | 113.1 | 4.9 | 4.40 | 4.03 |
| Jose Veras |   | mr | 27 | .738 | 151 | .298 | 117 | .462 | 120 | .474 | 31.3 | 4.9 | 4.39 | 4.09 |
| Justin Verlander | COP | sp | 25 | .715 | 598 | .296 | 377 | .428 | 391 | .444 | 100.4 | 4.5 | 4.04 | 4.17 |
| Carlos Villanueva |   | mr | 24 | .763 | 320 | .294 | 217 | .468 | 220 | .474 | 60.0 | 5.0 | 4.48 | 4.29 |
| Oscar Villarreal |   | mr | 26 | .950 | 116 | .259 | 103 | .613 | 105 | .625 | 30.5 | 7.3 | 6.55 | 6.98 |
| Ron Villone* |   | mr | 38 | .754 | 136 | .301 | 108 | .472 | 110 | .480 | 28.0 | 5.0 | 4.53 | 4.77 |
| Luis Vizcaino |   | mr | 33 | .837 | 124 | .306 | 109 | .537 | 110 | .542 | 30.8 | 6.0 | 5.41 | 5.25 |
| Edinson Volquez | LON | sp | 24 | .681 | 511 | .299 | 346 | .413 | 360 | .430 | 87.6 | 4.0 | 3.62 | 3.61 |
| Chris Volstad | MAD | sp | 21 | .648 | 269 | .271 | 138 | .378 | 143 | .392 | 36.3 | 3.8 | 3.48 | 3.30 |
| Cory Wade | Pal | mr | 25 | .584 | 198 | .222 | 98 | .356 | 102 | .371 | 19.9 | 2.5 | 2.26 | 2.11 |
| Doug Waechter |   | mr | 27 | .718 | 199 | .281 | 121 | .440 | 123 | .447 | 33.3 | 4.7 | 4.26 | 3.82 |
| Billy Wagner* | BT | cl | 36 | .517 | 118 | .237 | 60 | .326 | 60 | .326 | 11.5 | 2.2 | 1.99 | 1.68 |
| Adam Wainwright | MAD | sp | 26 | .688 | 404 | .272 | 229 | .421 | 232 | .426 | 56.1 | 3.8 | 3.44 | 3.14 |
| Tim Wakefield | OTR | sp | 41 | .689 | 539 | .239 | 321 | .426 | 334 | .443 | 82.0 | 4.1 | 3.67 | 3.54 |
| Jamie Walker* | OTR | mr | 36 | .981 | 130 | .315 | 111 | .624 | 112 | .629 | 36.6 | 8.5 | 7.79 | 7.53 |
| Tyler Walker |   | mr | 32 | .706 | 148 | .270 | 101 | .447 | 102 | .451 | 24.4 | 4.0 | 3.71 | 3.57 |
| Les Walrond* |   | mr | 31 | .915 | 28 | .464 | 26 | .531 | 26 | .531 | 7.9 | 7.3 | 6.19 | 6.21 |
| Chien-Ming Wang | MID | sp | 28 | .654 | 306 | .281 | 156 | .388 | 159 | .396 | 38.3 | 3.6 | 3.27 | 3.39 |
| Jarrod Washburn* |   | sp | 33 | .808 | 512 | .303 | 331 | .490 | 338 | .501 | 95.4 | 5.6 | 5.03 | 4.88 |
| Ehren Wassermann |   | mr | 27 | .914 | 77 | .351 | 53 | .525 | 54 | .535 | 19.1 | 8.6 | 7.87 | 6.35 |
| Chris Waters* |   | sp | 27 | .808 | 217 | .281 | 146 | .502 | 149 | .512 | 42.8 | 6.0 | 5.36 | 5.20 |
| David Weathers |   | mr | 38 | .778 | 226 | .310 | 147 | .473 | 150 | .482 | 39.5 | 5.0 | 4.61 | 4.61 |
| Jered Weaver | OTR | sp | 25 | .729 | 513 | .298 | 337 | .452 | 343 | .460 | 91.7 | 4.7 | 4.20 | 3.80 |
| Brandon Webb | TON | sp | 29 | .636 | 671 | .288 | 349 | .370 | 361 | .382 | 85.1 | 3.3 | 3.04 | 3.04 |
| Todd Wellemeyer | Pal | sp | 29 | .724 | 579 | .264 | 364 | .451 | 371 | .460 | 94.7 | 4.4 | 4.00 | 3.72 |
| Jared Wells |   | mr | 26 | .943 | 30 | .300 | 25 | .568 | 25 | .568 | 9.0 | 9.3 | 8.71 | 8.76 |
| Kip Wells |   | mr | 31 | .836 | 109 | .321 | 90 | .511 | 92 | .523 | 24.2 | 5.7 | 5.21 | 6.20 |
| Randy Wells |   | mr | 25 | .167 | 14 | .000 | 3 | .167 | 3 | .167 | 0.1 | 0.1 | 0.13 | 0.35 |
| Jake Westbrook |   | sp | 30 | .698 | 107 | .262 | 59 | .424 | 60 | .432 | 13.5 | 3.5 | 3.15 | 3.54 |
| Dan Wheeler | Pal | mr | 30 | .608 | 179 | .190 | 108 | .409 | 108 | .409 | 22.0 | 3.0 | 2.69 | 2.28 |
| Bill White* |   | mr | 29 | 1.337 | 17 | .353 | 25 | .833 | 25 | .833 | 10.0 | 22.4 | 20.17 | 20.85 |
| Dontrelle Willis* |   | sp | 26 | .884 | 64 | .219 | 73 | .598 | 74 | .607 | 19.3 | 7.2 | 6.51 | 7.65 |
| Brian Wilson | MUL | cl | 26 | .732 | 169 | .325 | 120 | .438 | 123 | .449 | 32.2 | 4.6 | 4.18 | 4.41 |
| C.J. Wilson* | ROK | cl | 27 | .842 | 136 | .301 | 114 | .533 | 116 | .542 | 31.7 | 6.0 | 5.54 | 5.77 |
| Matt Wise |   | mr | 32 | .963 | 23 | .348 | 21 | .618 | 21 | .618 | 7.3 | 9.4 | 8.42 | 7.88 |
| Randy Wolf* | CCL | sp | 31 | .746 | 557 | .305 | 368 | .447 | 380 | .462 | 100.7 | 4.8 | 4.29 | 4.30 |
| Brian Wolfe |   | mr | 27 | .662 | 64 | .250 | 35 | .407 | 35 | .407 | 7.5 | 3.1 | 2.77 | 2.61 |
| Kerry Wood | MUL | cl | 31 | .632 | 164 | .311 | 103 | .373 | 110 | .399 | 26.3 | 3.6 | 3.21 | 2.52 |
| Jake Woods* |   | mr | 26 | .964 | 61 | .279 | 54 | .621 | 55 | .632 | 16.2 | 7.8 | 6.93 | 7.29 |
| Mark Worrell |   | mr | 25 | 1.052 | 18 | .389 | 17 | .630 | 17 | .630 | 5.3 | 8.4 | 7.57 | 8.66 |
| Jamey Wright |   | mr | 33 | .739 | 271 | .325 | 159 | .420 | 167 | .441 | 45.9 | 4.8 | 4.41 | 4.74 |
| Wesley Wright* |   | mr | 23 | .733 | 147 | .252 | 118 | .472 | 122 | .488 | 30.5 | 4.8 | 4.44 | 4.21 |
| Michael Wuertz | ROK | mr | 29 | .740 | 135 | .296 | 86 | .455 | 86 | .455 | 22.2 | 4.5 | 4.02 | 4.15 |
| Keiichi Yabu |   | mr | 39 | .677 | 211 | .284 | 118 | .391 | 126 | .417 | 31.0 | 4.0 | 3.69 | 3.86 |
| Yasuhiko Yabuta |   | mr | 35 | .817 | 120 | .292 | 87 | .518 | 87 | .518 | 24.5 | 5.7 | 5.26 | 5.21 |
| Tyler Yates |   | mr | 30 | .737 | 219 | .301 | 150 | .453 | 152 | .459 | 40.8 | 5.0 | 4.50 | 4.43 |
| Chris Young | COP | sp | 29 | .694 | 279 | .254 | 194 | .447 | 195 | .449 | 49.2 | 4.3 | 3.89 | 3.50 |
| Carlos Zambrano | CCL | sp | 27 | .686 | 570 | .270 | 336 | .422 | 342 | .430 | 82.1 | 3.9 | 3.53 | 3.62 |
| Brad Ziegler | CRH | mr | 28 | .638 | 174 | .259 | 87 | .380 | 88 | .384 | 16.2 | 2.4 | 2.20 | 2.60 |
| Charlie Zink |   | sp | 28 | 1.105 | 23 | .478 | 16 | .640 | 16 | .640 | 7.3 | 15.2 | 13.69 | 12.25 |
| Barry Zito* |   | sp | 30 | .772 | 576 | .295 | 386 | .472 | 390 | .477 | 109.2 | 5.4 | 4.91 | 4.81 |
| Joel Zumaya |   | mr | 23 | .854 | 67 | .313 | 63 | .553 | 63 | .553 | 18.4 | 7.2 | 6.40 | 6.32 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% |
| David Aardsma | EDG | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 11 | .500 |
| Jeremy Accardo |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Alfredo Aceves |   | sp | 25 | 4 | 0 | .000 | 0 | 3 | .750 | 31 | 7.8 | 1 | 0 | .000 |
| Manny Acosta |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 |
| Mike Adams | MUL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Nick Adenhart |   | sp | 21 | 3 | 0 | .000 | 0 | 0 | .000 | 23 | 7.7 | 6 | 1 | .167 |
| Jon Adkins |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeremy Affeldt* | CRH | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 8 | .250 |
| Jonathan Albaladejo |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Matt Albers |   | mr | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 9 | 3.0 | 15 | 6 | .400 |
| Greg Aquino |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Alberto Arias |   | mr | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 4 | 2.0 | 6 | 2 | .333 |
| Tony Armas |   | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 0 | 0 | .000 |
| Jose Arredondo | COP | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Bronson Arroyo | BT | sp | 31 | 34 | 1 | .029 | 0 | 18 | .529 | 172 | 5.1 | 19 | 6 | .316 |
| Jose Ascanio |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Luis Ayala |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 |
| Brandon Backe |   | sp | 30 | 31 | 0 | .000 | 0 | 11 | .355 | 131 | 4.2 | 28 | 5 | .179 |
| Burke Badenhop |   | sp | 25 | 8 | 0 | .000 | 0 | 2 | .250 | 34 | 4.3 | 6 | 1 | .167 |
| Cha Seung Baek |   | sp | 28 | 21 | 0 | .000 | 0 | 8 | .381 | 82 | 3.9 | 24 | 12 | .500 |
| Homer Bailey |   | sp | 22 | 8 | 0 | .000 | 0 | 2 | .250 | 14 | 1.8 | 9 | 2 | .222 |
| Scott Baker | BON | sp | 26 | 28 | 0 | .000 | 0 | 18 | .643 | 156 | 5.6 | 14 | 5 | .357 |
| John Bale* |   | mr | 34 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 2 | 1 | .500 |
| Collin Balester |   | sp | 22 | 15 | 0 | .000 | 0 | 3 | .200 | 64 | 4.3 | 14 | 1 | .071 |
| Grant Balfour | COP | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Josh Banks |   | sp | 25 | 14 | 1 | .071 | 0 | 4 | .286 | 49 | 3.5 | 10 | 4 | .400 |
| Brian Bannister |   | sp | 27 | 32 | 1 | .031 | 0 | 11 | .344 | 156 | 4.9 | 18 | 5 | .278 |
| Jimmy Barthmaier |   | sp | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 13 | 4.3 | 1 | 0 | .000 |
| Brian Bass |   | mr | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 32 | 13 | .406 |
| Miguel Batista |   | mr | 37 | 20 | 0 | .000 | 0 | 5 | .250 | 85 | 4.3 | 23 | 9 | .391 |
| Rick Bauer |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Denny Bautista |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 |
| Yorman Bazardo |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| T.J. Beam |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Josh Beckett | Pal | sp | 28 | 27 | 1 | .037 | 0 | 16 | .593 | 134 | 5.0 | 12 | 8 | .667 |
| Erik Bedard* | GEO | sp | 29 | 15 | 0 | .000 | 0 | 7 | .467 | 66 | 4.4 | 10 | 3 | .300 |
| Joe Beimel* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 4 | .093 |
| Matt Belisle |   | sp | 28 | 6 | 0 | .000 | 0 | 1 | .167 | 30 | 5.0 | 6 | 2 | .333 |
| Heath Bell | MUL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Francis Beltran |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Armando Benitez |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Jeff Bennett | TON | mr | 28 | 4 | 0 | .000 | 0 | 1 | .250 | 13 | 3.3 | 21 | 6 | .286 |
| Joaquin Benoit | OTR | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Jason Bergmann |   | sp | 26 | 22 | 1 | .045 | 0 | 10 | .455 | 71 | 3.2 | 11 | 8 | .727 |
| Rafael Betancourt | GEO | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 |
| Randor Bierd |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 |
| Chad Billingsley | TON | sp | 23 | 32 | 1 | .031 | 1 | 20 | .625 | 135 | 4.2 | 20 | 4 | .200 |
| Kurt Birkins* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Nick Blackburn |   | sp | 26 | 33 | 0 | .000 | 0 | 19 | .576 | 142 | 4.3 | 23 | 6 | .261 |
| Joe Blanton |   | sp | 27 | 33 | 0 | .000 | 0 | 14 | .424 | 144 | 4.4 | 19 | 8 | .421 |
| Jerry Blevins* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 |
| Mitchell Boggs |   | sp | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 31 | 5.2 | 6 | 3 | .500 |
| Jeremy Bonderman |   | sp | 25 | 12 | 0 | .000 | 0 | 5 | .417 | 61 | 5.1 | 13 | 8 | .615 |
| Eddie Bonine |   | sp | 27 | 5 | 0 | .000 | 0 | 2 | .400 | 29 | 5.8 | 5 | 0 | .000 |
| Boof Bonser |   | mr | 26 | 12 | 0 | .000 | 0 | 6 | .500 | 45 | 3.8 | 26 | 14 | .538 |
| Chris Bootcheck |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Dave Borkowski |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Joe Borowski |   | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Michael Bowden |   | sp | 21 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 0 | 0 | .000 |
| Cedrick Bowers* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Micah Bowie* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Blaine Boyer |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 9 | .409 |
| Dallas Braden* |   | sp | 24 | 10 | 0 | .000 | 0 | 4 | .400 | 40 | 4.0 | 4 | 1 | .250 |
| Chad Bradford | MID | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 |
| Bill Bray* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 45 | 9 | .200 |
| Yhency Brazoban |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Craig Breslow* | MID | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 |
| Chris Britton |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Lance Broadway |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 0 | 0 | .000 |
| Doug Brocail |   | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 6 | .500 |
| Andrew Brown |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Jonathan Broxton | CCL | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Brian Bruney |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Clay Buchholz | COP | sp | 23 | 15 | 1 | .067 | 0 | 3 | .200 | 68 | 4.5 | 14 | 7 | .500 |
| Taylor Buchholz | TON | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 |
| Billy Buckner |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Mark Buehrle* | BON | sp | 29 | 34 | 1 | .029 | 0 | 24 | .706 | 170 | 5.0 | 19 | 7 | .368 |
| Francisley Bueno* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Ryan Bukvich |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Jason Bulger |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 |
| Bryan Bullington |   | sp | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 5 | 2.5 | 0 | 0 | .000 |
| A.J. Burnett | TON | sp | 31 | 34 | 1 | .029 | 0 | 19 | .559 | 149 | 4.4 | 22 | 9 | .409 |
| Sean Burnett* | WIZ | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| Brian Burres* |   | sp | 27 | 22 | 0 | .000 | 0 | 7 | .318 | 96 | 4.4 | 30 | 14 | .467 |
| Jared Burton | MAD | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 |
| Dave Bush | OTR | sp | 28 | 29 | 0 | .000 | 0 | 16 | .552 | 142 | 4.9 | 6 | 3 | .500 |
| Paul Byrd |   | sp | 37 | 30 | 1 | .033 | 0 | 13 | .433 | 120 | 4.0 | 20 | 5 | .250 |
| Tim Byrdak* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 |
| Daniel Cabrera |   | sp | 27 | 30 | 2 | .067 | 0 | 13 | .433 | 151 | 5.0 | 30 | 11 | .367 |
| Fernando Cabrera |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 |
| Matt Cain | LON | sp | 23 | 34 | 1 | .029 | 1 | 21 | .618 | 108 | 3.2 | 23 | 4 | .174 |
| Kiko Calero |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Kevin Cameron |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Shawn Camp |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 |
| Jorge Campillo | WIZ | sp | 29 | 25 | 1 | .040 | 0 | 10 | .400 | 113 | 4.5 | 14 | 5 | .357 |
| Jose Capellan |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Matt Capps | MUL | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jesse Carlson* | BON | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 3 | .086 |
| Buddy Carlyle | LON | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Fausto Carmona |   | sp | 24 | 22 | 1 | .045 | 1 | 9 | .409 | 129 | 5.9 | 20 | 10 | .500 |
| Andrew Carpenter |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chris Carpenter | TON | sp | 33 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 2 | 2 | 1.000 |
| D.J. Carrasco |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 |
| Santiago Casilla | OTR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 |
| Jack Cassel |   | mr | 27 | 3 | 0 | .000 | 0 | 0 | .000 | 13 | 4.3 | 7 | 1 | .143 |
| Alberto Castillo* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 1 | .053 |
| Shawn Chacon |   | sp | 30 | 15 | 0 | .000 | 0 | 9 | .600 | 70 | 4.7 | 2 | 0 | .000 |
| Joba Chamberlain | BT | mr | 22 | 12 | 0 | .000 | 0 | 7 | .583 | 53 | 4.4 | 12 | 4 | .333 |
| Jesse Chavez |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Rocky Cherry |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 |
| Matt Chico* |   | sp | 25 | 8 | 0 | .000 | 0 | 1 | .125 | 31 | 3.9 | 3 | 1 | .333 |
| Vinnie Chulk |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Tyler Clippard |   | sp | 23 | 2 | 0 | .000 | 0 | 1 | .500 | 7 | 3.5 | 3 | 0 | .000 |
| Todd Coffey |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 |
| Phil Coke* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Jesus Colome |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 9 | .643 |
| Bartolo Colon |   | sp | 35 | 7 | 0 | .000 | 0 | 3 | .429 | 35 | 5.0 | 2 | 1 | .500 |
| Clay Condrey |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 |
| Jose Contreras |   | sp | 36 | 20 | 1 | .050 | 0 | 11 | .550 | 102 | 5.1 | 15 | 3 | .200 |
| Aaron Cook | MAD | sp | 29 | 32 | 2 | .063 | 1 | 18 | .563 | 158 | 4.9 | 11 | 2 | .182 |
| Roy Corcoran | EDG | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 |
| Chad Cordero |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Francisco Cordero | CRH | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Bryan Corey |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 |
| Lance Cormier |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 19 | 11 | .579 |
| Manuel Corpas |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 |
| Kevin Correia | MUL | sp | 27 | 19 | 0 | .000 | 0 | 6 | .316 | 75 | 3.9 | 18 | 8 | .444 |
| Neal Cotts* | CRH | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 6 | .182 |
| Jesse Crain | BON | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 |
| Francisco Cruceta |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Juan Cruz | TON | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Johnny Cueto | Pal | sp | 22 | 31 | 0 | .000 | 0 | 14 | .452 | 117 | 3.8 | 7 | 3 | .429 |
| John Danks* | EDG | sp | 23 | 33 | 0 | .000 | 0 | 19 | .576 | 141 | 4.3 | 27 | 8 | .296 |
| Kyle Davies |   | sp | 24 | 21 | 0 | .000 | 0 | 8 | .381 | 93 | 4.4 | 13 | 1 | .077 |
| Doug Davis* |   | sp | 32 | 26 | 0 | .000 | 0 | 14 | .538 | 120 | 4.6 | 20 | 7 | .350 |
| Jason Davis |   | mr | 28 | 4 | 0 | .000 | 0 | 2 | .500 | 13 | 3.3 | 3 | 0 | .000 |
| Eulogio De La Cruz |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 7 | 6 | .857 |
| Jorge De La Rosa* | MUL | sp | 27 | 23 | 0 | .000 | 0 | 10 | .435 | 110 | 4.8 | 22 | 7 | .318 |
| Valerio de los Santos* |   | sp | 35 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 2 | 2 | 1.000 |
| Manny Delcarmen | GEO | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 8 | .421 |
| Jesus Delgado |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Ryan Dempster | CRH | sp | 31 | 33 | 1 | .030 | 0 | 21 | .636 | 181 | 5.5 | 12 | 2 | .167 |
| Matt DeSalvo |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Elmer Dessens |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Joey Devine | BT | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Joselo Diaz |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| R.A. Dickey | OTR | mr | 33 | 14 | 0 | .000 | 0 | 6 | .429 | 60 | 4.3 | 14 | 3 | .214 |
| Mark DiFelice |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Tim Dillard |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Lenny DiNardo* |   | mr | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 8 | 4 | .500 |
| Scott Dohmann |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Freddy Dolsi |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 12 | .400 |
| Brendan Donnelly |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Octavio Dotel |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 |
| Scott Downs* | EDG | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Justin Duchscherer | COP | sp | 30 | 22 | 1 | .045 | 1 | 15 | .682 | 97 | 4.4 | 13 | 2 | .154 |
| Brandon Duckworth |   | sp | 32 | 7 | 0 | .000 | 0 | 4 | .571 | 32 | 4.6 | 4 | 2 | .500 |
| Zach Duke* |   | sp | 25 | 31 | 1 | .032 | 1 | 14 | .452 | 139 | 4.5 | 16 | 5 | .313 |
| Phil Dumatrait* |   | sp | 26 | 11 | 0 | .000 | 0 | 3 | .273 | 67 | 6.1 | 15 | 2 | .133 |
| Chad Durbin | MAD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 11 | .423 |
| Adam Eaton |   | sp | 30 | 19 | 0 | .000 | 0 | 10 | .526 | 75 | 3.9 | 18 | 7 | .389 |
| Mike Ekstrom |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Scott Elarton |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Scott Elbert* |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Alan Embree* |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 |
| Geno Espineli* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Shawn Estes* |   | sp | 35 | 8 | 0 | .000 | 0 | 3 | .375 | 26 | 3.3 | 13 | 4 | .308 |
| Marco Estrada |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Dana Eveland* |   | sp | 24 | 29 | 1 | .034 | 0 | 13 | .448 | 103 | 3.6 | 25 | 7 | .280 |
| Scott Eyre* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 |
| Brian Falkenborg |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Kyle Farnsworth |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 |
| Ryan Feierabend* |   | sp | 22 | 8 | 0 | .000 | 0 | 2 | .250 | 40 | 5.0 | 5 | 3 | .600 |
| Scott Feldman | MID | sp | 25 | 25 | 0 | .000 | 0 | 13 | .520 | 121 | 4.8 | 13 | 10 | .769 |
| Pedro Feliciano* | MAD | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 56 | 7 | .125 |
| Nelson Figueroa |   | mr | 34 | 6 | 0 | .000 | 0 | 2 | .333 | 22 | 3.7 | 5 | 1 | .200 |
| Randy Flores* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 5 | .179 |
| Gavin Floyd | TON | sp | 25 | 33 | 1 | .030 | 0 | 19 | .576 | 195 | 5.9 | 21 | 6 | .286 |
| Josh Fogg |   | sp | 31 | 14 | 0 | .000 | 0 | 3 | .214 | 66 | 4.7 | 14 | 11 | .786 |
| Casey Fossum* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 8 | .571 |
| Keith Foulke |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Chad Fox |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeff Francis* |   | sp | 27 | 24 | 0 | .000 | 0 | 12 | .500 | 83 | 3.5 | 16 | 8 | .500 |
| Frank Francisco | EDG | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Ryan Franklin |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 |
| Jason Frasor | MID | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 |
| Brian Fuentes* | CCL | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 |
| Kazuo Fukumori |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Jeff Fulchino |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 |
| Kason Gabbard* |   | sp | 26 | 12 | 0 | .000 | 0 | 2 | .167 | 79 | 6.6 | 14 | 4 | .286 |
| Eric Gagne |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Armando Galarraga |   | sp | 26 | 28 | 0 | .000 | 0 | 16 | .571 | 155 | 5.5 | 17 | 6 | .353 |
| Sean Gallagher |   | sp | 22 | 21 | 0 | .000 | 0 | 6 | .286 | 93 | 4.4 | 14 | 6 | .429 |
| Yovani Gallardo | LON | sp | 22 | 4 | 0 | .000 | 0 | 3 | .750 | 12 | 3.0 | 0 | 0 | .000 |
| Freddy Garcia |   | sp | 32 | 3 | 0 | .000 | 0 | 0 | .000 | 19 | 6.3 | 1 | 1 | 1.000 |
| Jaime Garcia* |   | mr | 21 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 6 | 1 | .167 |
| Lee Gardner |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Jon Garland |   | sp | 28 | 32 | 1 | .031 | 0 | 18 | .563 | 170 | 5.3 | 16 | 4 | .250 |
| Matt Garza | GEO | sp | 24 | 30 | 3 | .100 | 2 | 15 | .500 | 128 | 4.3 | 21 | 2 | .095 |
| Chad Gaudin |   | mr | 25 | 6 | 0 | .000 | 0 | 4 | .667 | 43 | 7.2 | 12 | 7 | .583 |
| Geoff Geary | TON | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 |
| Josh Geer |   | sp | 25 | 5 | 0 | .000 | 0 | 1 | .200 | 25 | 5.0 | 0 | 0 | .000 |
| Franklyn German |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Justin Germano |   | sp | 25 | 6 | 0 | .000 | 0 | 3 | .500 | 18 | 3.0 | 5 | 5 | 1.000 |
| Dan Giese | BON | mr | 31 | 3 | 0 | .000 | 0 | 2 | .667 | 10 | 3.3 | 9 | 5 | .556 |
| Matt Ginter |   | sp | 30 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 0 | 0 | .000 |
| Tom Glavine* |   | sp | 42 | 13 | 0 | .000 | 0 | 5 | .385 | 70 | 5.4 | 8 | 1 | .125 |
| Gary Glover |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 1 | .048 |
| Jimmy Gobble* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 |
| Edgar Gonzalez |   | mr | 25 | 6 | 0 | .000 | 0 | 1 | .167 | 34 | 5.7 | 3 | 0 | .000 |
| Enrique Gonzalez |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Gio Gonzalez* |   | sp | 22 | 7 | 0 | .000 | 0 | 0 | .000 | 25 | 3.6 | 8 | 4 | .500 |
| Mike Gonzalez* |   | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 |
| Brian Gordon |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Tom Gordon |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Tom Gorzelanny* |   | sp | 25 | 21 | 0 | .000 | 0 | 7 | .333 | 100 | 4.8 | 17 | 6 | .353 |
| John Grabow* | TON | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| Jeff Gray |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Sean Green |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 17 | .405 |
| Kevin Gregg | BT | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Zack Greinke | COP | sp | 24 | 32 | 1 | .031 | 0 | 23 | .719 | 150 | 4.7 | 13 | 3 | .231 |
| Jason Grilli | COP | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 |
| Eddie Guardado* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 |
| Matt Guerrier | MID | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 13 | .342 |
| Carlos Guevara |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeremy Guthrie | MID | sp | 29 | 30 | 1 | .033 | 0 | 19 | .633 | 128 | 4.3 | 20 | 6 | .300 |
| Angel Guzman |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 1 | 0 | .000 |
| Charlie Haeger |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Roy Halladay | ROK | sp | 31 | 33 | 9 | .273 | 2 | 23 | .697 | 149 | 4.5 | 8 | 2 | .250 |
| Cole Hamels* | BT | sp | 24 | 33 | 2 | .061 | 2 | 23 | .697 | 152 | 4.6 | 13 | 5 | .385 |
| Jason Hammel | EDG | mr | 25 | 5 | 0 | .000 | 0 | 3 | .600 | 19 | 3.8 | 4 | 2 | .500 |
| Justin Hampson* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 |
| Mike Hampton* |   | sp | 35 | 13 | 0 | .000 | 0 | 9 | .692 | 64 | 4.9 | 3 | 3 | 1.000 |
| Joel Hanrahan | CCL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Devern Hansack |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Craig Hansen |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 15 | .500 |
| J.A. Happ* |   | sp | 25 | 4 | 0 | .000 | 0 | 3 | .750 | 19 | 4.8 | 8 | 2 | .250 |
| Aaron Harang | GEO | sp | 30 | 29 | 1 | .034 | 1 | 17 | .586 | 102 | 3.5 | 5 | 2 | .400 |
| Rich Harden | COP | sp | 26 | 25 | 0 | .000 | 0 | 14 | .560 | 133 | 5.3 | 8 | 0 | .000 |
| Dan Haren | LON | sp | 27 | 33 | 1 | .030 | 1 | 23 | .697 | 168 | 5.1 | 8 | 7 | .875 |
| Matt Harrison* |   | sp | 22 | 15 | 1 | .067 | 1 | 6 | .400 | 120 | 8.0 | 12 | 2 | .167 |
| Kevin Hart |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 |
| LaTroy Hawkins |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 9 | .692 |
| Dirk Hayhurst |   | mr | 27 | 3 | 0 | .000 | 0 | 0 | .000 | 18 | 6.0 | 7 | 3 | .429 |
| Aaron Heilman |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 11 | .393 |
| Mark Hendrickson* |   | sp | 34 | 19 | 0 | .000 | 0 | 4 | .211 | 96 | 5.1 | 16 | 6 | .375 |
| Sean Henn* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Brad Hennessey |   | mr | 28 | 4 | 1 | .250 | 0 | 3 | .750 | 18 | 4.5 | 11 | 0 | .000 |
| Clay Hensley |   | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 14 | 9 | .643 |
| Matt Herges |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 3 | .150 |
| Felix Hernandez | ROK | sp | 22 | 31 | 2 | .065 | 0 | 19 | .613 | 112 | 3.6 | 11 | 4 | .364 |
| Fernando Hernandez |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Livan Hernandez |   | sp | 33 | 31 | 2 | .065 | 0 | 12 | .387 | 183 | 5.9 | 16 | 5 | .313 |
| Runelvys Hernandez |   | sp | 30 | 4 | 0 | .000 | 0 | 0 | .000 | 12 | 3.0 | 1 | 0 | .000 |
| Danny Herrera* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 |
| Yoslan Herrera |   | sp | 27 | 5 | 0 | .000 | 0 | 1 | .200 | 35 | 7.0 | 5 | 0 | .000 |
| Rich Hill* |   | sp | 28 | 5 | 0 | .000 | 0 | 1 | .200 | 23 | 4.6 | 4 | 1 | .250 |
| Shawn Hill |   | sp | 27 | 12 | 0 | .000 | 0 | 3 | .250 | 45 | 3.8 | 6 | 4 | .667 |
| Mike Hinckley* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Alex Hinshaw* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 4 | .125 |
| Jason Hirsh |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 4 | 1 | .250 |
| Luke Hochevar |   | sp | 24 | 22 | 0 | .000 | 0 | 8 | .364 | 63 | 2.9 | 10 | 4 | .400 |
| Trevor Hoffman | Pal | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| J.P. Howell* | MID | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 4 | .154 |
| Bob Howry | WIZ | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 |
| Tim Hudson | GEO | sp | 32 | 22 | 1 | .045 | 1 | 16 | .727 | 104 | 4.7 | 10 | 4 | .400 |
| Phil Hughes | COP | sp | 22 | 8 | 0 | .000 | 0 | 2 | .250 | 33 | 4.1 | 7 | 4 | .571 |
| Philip Humber |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Tommy Hunter |   | sp | 21 | 3 | 0 | .000 | 0 | 0 | .000 | 12 | 4.0 | 3 | 1 | .333 |
| Eric Hurley |   | sp | 22 | 5 | 0 | .000 | 0 | 1 | .200 | 20 | 4.0 | 3 | 0 | .000 |
| Kei Igawa* |   | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 2 | 0 | .000 |
| Jason Isringhausen |   | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 |
| Edwin Jackson |   | sp | 24 | 31 | 0 | .000 | 0 | 15 | .484 | 156 | 5.0 | 20 | 4 | .200 |
| Zach Jackson* |   | sp | 25 | 9 | 0 | .000 | 0 | 4 | .444 | 54 | 6.0 | 3 | 3 | 1.000 |
| Chuck James* |   | sp | 26 | 7 | 0 | .000 | 0 | 0 | .000 | 21 | 3.0 | 2 | 0 | .000 |
| Bobby Jenks | OTR | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jason Jennings |   | sp | 29 | 6 | 0 | .000 | 0 | 1 | .167 | 16 | 2.7 | 6 | 0 | .000 |
| Kevin Jepsen |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Cesar Jimenez* |   | mr | 23 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 11 | 4 | .364 |
| Kelvin Jimenez |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Ubaldo Jimenez | TON | sp | 24 | 34 | 1 | .029 | 0 | 18 | .529 | 144 | 4.2 | 15 | 6 | .400 |
| Jason Johnson |   | mr | 34 | 2 | 0 | .000 | 0 | 1 | .500 | 11 | 5.5 | 9 | 4 | .444 |
| Jim Johnson | GEO | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 |
| Josh Johnson | LON | sp | 24 | 14 | 1 | .071 | 0 | 10 | .714 | 78 | 5.6 | 5 | 1 | .200 |
| Randy Johnson* | ROK | sp | 44 | 30 | 2 | .067 | 0 | 18 | .600 | 113 | 3.8 | 10 | 2 | .200 |
| Todd Jones |   | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 |
| Jorge Julio |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Jair Jurrjens | WIZ | sp | 22 | 31 | 0 | .000 | 0 | 17 | .548 | 157 | 5.1 | 10 | 1 | .100 |
| Jeff Karstens |   | sp | 25 | 9 | 1 | .111 | 1 | 5 | .556 | 22 | 2.4 | 5 | 5 | 1.000 |
| Scott Kazmir* | GEO | sp | 24 | 27 | 0 | .000 | 0 | 13 | .481 | 140 | 5.2 | 13 | 2 | .154 |
| Kyle Kendrick |   | sp | 23 | 30 | 0 | .000 | 0 | 13 | .433 | 178 | 5.9 | 25 | 11 | .440 |
| Ian Kennedy |   | sp | 23 | 9 | 0 | .000 | 0 | 2 | .222 | 37 | 4.1 | 7 | 2 | .286 |
| Logan Kensing |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 8 | .296 |
| Clayton Kershaw* | MUL | sp | 20 | 21 | 0 | .000 | 0 | 8 | .381 | 93 | 4.4 | 20 | 6 | .300 |
| Ray King* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Josh Kinney |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Brandon Knight |   | sp | 32 | 2 | 0 | .000 | 0 | 0 | .000 | 17 | 8.5 | 0 | 0 | .000 |
| Masa Kobayashi |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 |
| Bobby Korecky |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Eddie Kunz |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Hong-Chih Kuo* | Pal | mr | 26 | 3 | 0 | .000 | 0 | 0 | .000 | 13 | 4.3 | 6 | 3 | .500 |
| Hiroki Kuroda | WIZ | sp | 33 | 31 | 2 | .065 | 2 | 18 | .581 | 125 | 4.0 | 21 | 4 | .190 |
| John Lackey | COP | sp | 29 | 24 | 3 | .125 | 0 | 16 | .667 | 121 | 5.0 | 6 | 0 | .000 |
| Aaron Laffey* |   | sp | 23 | 16 | 0 | .000 | 0 | 10 | .625 | 97 | 6.1 | 9 | 5 | .556 |
| Chris Lambert |   | mr | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 4 | 2 | .500 |
| John Lannan* |   | sp | 23 | 31 | 0 | .000 | 0 | 21 | .677 | 117 | 3.8 | 8 | 6 | .750 |
| Brandon League |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Wade LeBlanc* |   | sp | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 18 | 4.5 | 2 | 0 | .000 |
| Wil Ledezma* |   | mr | 27 | 6 | 0 | .000 | 0 | 0 | .000 | 27 | 4.5 | 9 | 1 | .111 |
| Cliff Lee* | MID | sp | 29 | 31 | 4 | .129 | 2 | 23 | .742 | 171 | 5.5 | 10 | 2 | .200 |
| Jon Lester* | EDG | sp | 24 | 33 | 2 | .061 | 2 | 20 | .606 | 177 | 5.4 | 22 | 5 | .227 |
| Jensen Lewis |   | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 |
| Scott Lewis* |   | sp | 24 | 4 | 0 | .000 | 0 | 2 | .500 | 31 | 7.8 | 0 | 0 | .000 |
| Brad Lidge | Pal | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jon Lieber |   | mr | 38 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 |
| Ted Lilly* | OTR | sp | 32 | 34 | 0 | .000 | 0 | 21 | .618 | 189 | 5.6 | 17 | 5 | .294 |
| Tim Lincecum | WIZ | sp | 24 | 33 | 2 | .061 | 1 | 26 | .788 | 149 | 4.5 | 14 | 8 | .571 |
| Mike Lincoln |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 13 | .619 |
| Matt Lindstrom |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 |
| Scott Linebrink | EDG | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 |
| Francisco Liriano* | ROK | sp | 24 | 14 | 0 | .000 | 0 | 7 | .500 | 58 | 4.1 | 9 | 2 | .222 |
| Jesse Litsch | EDG | sp | 23 | 28 | 2 | .071 | 2 | 15 | .536 | 144 | 5.1 | 21 | 8 | .381 |
| Wes Littleton |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Radhames Liz |   | sp | 25 | 17 | 0 | .000 | 0 | 3 | .176 | 101 | 5.9 | 17 | 7 | .412 |
| Esteban Loaiza |   | mr | 36 | 3 | 0 | .000 | 0 | 0 | .000 | 18 | 6.0 | 1 | 1 | 1.000 |
| Kameron Loe |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Adam Loewen* |   | sp | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 19 | 4.8 | 5 | 3 | .600 |
| Boone Logan* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 |
| Kyle Lohse | CCL | sp | 29 | 33 | 0 | .000 | 0 | 20 | .606 | 140 | 4.2 | 10 | 2 | .200 |
| Braden Looper |   | sp | 33 | 33 | 1 | .030 | 1 | 15 | .455 | 146 | 4.4 | 16 | 5 | .313 |
| Aquilino Lopez |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 |
| Javier Lopez* | OTR | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 6 | .154 |
| Shane Loux |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Derek Lowe | BON | sp | 35 | 34 | 1 | .029 | 0 | 20 | .588 | 147 | 4.3 | 14 | 5 | .357 |
| Mark Lowe |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 |
| Devon Lowery |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Brandon Lyon | Pal | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Mike MacDougal |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Greg Maddux | Pal | sp | 42 | 33 | 0 | .000 | 0 | 17 | .515 | 127 | 3.8 | 14 | 4 | .286 |
| Warner Madrigal |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 10 | 2 | .200 |
| Ryan Madson | CCL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| Ron Mahay* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 9 | .290 |
| Paul Maholm* | MAD | sp | 26 | 31 | 1 | .032 | 0 | 19 | .613 | 130 | 4.2 | 11 | 4 | .364 |
| John Maine | BT | sp | 27 | 25 | 0 | .000 | 0 | 11 | .440 | 128 | 5.1 | 17 | 5 | .294 |
| Gary Majewski |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Charlie Manning* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 12 | .293 |
| Shaun Marcum | COP | sp | 26 | 25 | 0 | .000 | 0 | 15 | .600 | 123 | 4.9 | 18 | 5 | .278 |
| Carlos Marmol | WIZ | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Jason Marquis | CCL | sp | 29 | 28 | 0 | .000 | 0 | 12 | .429 | 160 | 5.7 | 24 | 8 | .333 |
| Sean Marshall* | LON | mr | 25 | 7 | 0 | .000 | 0 | 3 | .429 | 22 | 3.1 | 16 | 4 | .250 |
| Damaso Marte* | WIZ | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 10 | .294 |
| Pedro Martinez |   | sp | 36 | 20 | 0 | .000 | 0 | 6 | .300 | 92 | 4.6 | 7 | 4 | .571 |
| Shairon Martis |   | sp | 21 | 4 | 0 | .000 | 0 | 0 | .000 | 17 | 4.3 | 4 | 1 | .250 |
| Nick Masset | GEO | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 16 | 4 | .250 |
| Justin Masterson | OTR | mr | 23 | 9 | 0 | .000 | 0 | 5 | .556 | 34 | 3.8 | 10 | 2 | .200 |
| Tom Mastny |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 10 | 6 | .600 |
| Doug Mathis |   | sp | 25 | 4 | 0 | .000 | 0 | 1 | .250 | 21 | 5.3 | 4 | 2 | .500 |
| Osiris Matos |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Daisuke Matsuzaka | OTR | sp | 27 | 29 | 0 | .000 | 0 | 14 | .483 | 160 | 5.5 | 10 | 3 | .300 |
| Brandon McCarthy | EDG | sp | 24 | 5 | 0 | .000 | 0 | 2 | .400 | 31 | 6.2 | 2 | 2 | 1.000 |
| Kyle McClellan | MAD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 11 | .423 |
| Seth McClung | EDG | mr | 27 | 12 | 0 | .000 | 0 | 5 | .417 | 50 | 4.2 | 16 | 3 | .188 |
| Bob McCrory |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 |
| James McDonald |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Dustin McGowan |   | sp | 26 | 19 | 1 | .053 | 0 | 9 | .474 | 61 | 3.2 | 10 | 5 | .500 |
| Gil Meche | CRH | sp | 29 | 34 | 0 | .000 | 0 | 21 | .618 | 141 | 4.1 | 19 | 1 | .053 |
| Brandon Medders |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Evan Meek |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Jon Meloan |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Luis Mendoza |   | mr | 24 | 11 | 0 | .000 | 0 | 1 | .091 | 56 | 5.1 | 19 | 11 | .579 |
| Kent Mercker* |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Cla Meredith |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 |
| Randy Messenger |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Dan Meyer* |   | mr | 26 | 4 | 0 | .000 | 0 | 0 | .000 | 14 | 3.5 | 6 | 2 | .333 |
| Kam Mickolio |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Jose Mijares* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Andrew Miller* | GEO | sp | 23 | 20 | 0 | .000 | 0 | 6 | .300 | 91 | 4.6 | 20 | 7 | .350 |
| Jim Miller |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Justin Miller |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 |
| Trever Miller* |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 14 | .368 |
| Kevin Millwood |   | sp | 33 | 29 | 3 | .103 | 0 | 11 | .379 | 132 | 4.6 | 13 | 6 | .462 |
| Zach Miner | GEO | mr | 26 | 13 | 0 | .000 | 0 | 8 | .615 | 93 | 7.2 | 28 | 13 | .464 |
| Pat Misch* |   | mr | 26 | 7 | 0 | .000 | 0 | 1 | .143 | 27 | 3.9 | 4 | 1 | .250 |
| Garrett Mock | CCL | mr | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 7 | 2.3 | 11 | 5 | .455 |
| Brian Moehler |   | sp | 36 | 26 | 0 | .000 | 0 | 9 | .346 | 109 | 4.2 | 23 | 4 | .174 |
| Franklin Morales* |   | sp | 22 | 5 | 0 | .000 | 0 | 2 | .400 | 22 | 4.4 | 3 | 2 | .667 |
| Juan Morillo |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Matt Morris |   | sp | 33 | 5 | 0 | .000 | 0 | 0 | .000 | 17 | 3.4 | 3 | 1 | .333 |
| Brandon Morrow | CRH | mr | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 23 | 4.6 | 16 | 3 | .188 |
| Charlie Morton | LON | sp | 24 | 15 | 0 | .000 | 0 | 6 | .400 | 67 | 4.5 | 13 | 4 | .308 |
| Dustin Moseley |   | sp | 26 | 10 | 0 | .000 | 0 | 0 | .000 | 51 | 5.1 | 10 | 1 | .100 |
| Guillermo Mota |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 |
| Jason Motte |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Jamie Moyer* | LON | sp | 45 | 33 | 0 | .000 | 0 | 19 | .576 | 172 | 5.2 | 21 | 3 | .143 |
| Peter Moylan |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Edward Mujica |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Mark Mulder* |   | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 4 | 1 | .250 |
| Carlos Muniz |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| A.J. Murray* |   | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 18 | 9.0 | 4 | 0 | .000 |
| Neal Musser* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Mussina | MID | sp | 39 | 34 | 0 | .000 | 0 | 21 | .618 | 174 | 5.1 | 7 | 2 | .286 |
| Brett Myers | CRH | sp | 27 | 30 | 2 | .067 | 1 | 15 | .500 | 130 | 4.3 | 22 | 11 | .500 |
| Joe Nathan | WIZ | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Joe Nelson | CCL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 |
| Pat Neshek | BON | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Josh Newman* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Jeff Niemann |   | mr | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 4 | 1 | .250 |
| Jonathon Niese* |   | sp | 21 | 3 | 0 | .000 | 0 | 1 | .333 | 16 | 5.3 | 2 | 1 | .500 |
| Fernando Nieve |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Dustin Nippert |   | mr | 27 | 6 | 0 | .000 | 0 | 1 | .167 | 22 | 3.7 | 18 | 10 | .556 |
| Ricky Nolasco | CCL | sp | 25 | 32 | 1 | .031 | 1 | 23 | .719 | 154 | 4.8 | 12 | 3 | .250 |
| Hideo Nomo |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Leo Nunez | ROK | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Vladimir Nunez |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Mike O'Connor* |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 |
| Darren O'Day | MID | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 |
| Eric O'Flaherty* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Ross Ohlendorf |   | mr | 25 | 5 | 0 | .000 | 0 | 1 | .200 | 19 | 3.8 | 7 | 4 | .571 |
| Will Ohman* | MAD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 10 | .278 |
| Hideki Okajima* | COP | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 2 | .074 |
| Darren Oliver* | GEO | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 |
| Scott Olsen* |   | sp | 24 | 33 | 0 | .000 | 0 | 17 | .515 | 157 | 4.8 | 16 | 7 | .438 |
| Garrett Olson* |   | sp | 24 | 26 | 0 | .000 | 0 | 8 | .308 | 148 | 5.7 | 31 | 15 | .484 |
| Franquelis Osoria |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 0 | .000 |
| Roy Oswalt | BT | sp | 30 | 32 | 3 | .094 | 2 | 22 | .688 | 135 | 4.2 | 10 | 5 | .500 |
| Josh Outman* |   | sp | 23 | 4 | 0 | .000 | 0 | 2 | .500 | 18 | 4.5 | 2 | 2 | 1.000 |
| Micah Owings | MUL | sp | 25 | 18 | 0 | .000 | 0 | 9 | .500 | 76 | 4.2 | 18 | 8 | .444 |
| Vicente Padilla |   | sp | 30 | 29 | 1 | .034 | 1 | 12 | .414 | 178 | 6.1 | 7 | 1 | .143 |
| Matt Palmer |   | sp | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 11 | 3.7 | 5 | 1 | .200 |
| Jonathan Papelbon | BON | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Parisi |   | mr | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 13 | 6.5 | 3 | 3 | 1.000 |
| Chan Ho Park |   | mr | 35 | 5 | 0 | .000 | 0 | 2 | .400 | 20 | 4.0 | 24 | 10 | .417 |
| Bobby Parnell |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Chad Paronto |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| James Parr |   | sp | 22 | 5 | 0 | .000 | 0 | 2 | .400 | 36 | 7.2 | 4 | 0 | .000 |
| Manny Parra* |   | sp | 25 | 29 | 0 | .000 | 0 | 10 | .345 | 138 | 4.8 | 20 | 6 | .300 |
| John Parrish* |   | mr | 30 | 6 | 0 | .000 | 0 | 2 | .333 | 37 | 6.2 | 1 | 0 | .000 |
| Scott Patterson |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| David Pauley |   | mr | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 15 | 7.5 | 5 | 2 | .400 |
| Carl Pavano |   | sp | 32 | 7 | 0 | .000 | 0 | 1 | .143 | 29 | 4.1 | 6 | 2 | .333 |
| Jake Peavy | MUL | sp | 27 | 27 | 1 | .037 | 0 | 19 | .704 | 99 | 3.7 | 1 | 0 | .000 |
| Jailen Peguero |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Mike Pelfrey |   | sp | 24 | 32 | 2 | .063 | 0 | 19 | .594 | 161 | 5.0 | 15 | 6 | .400 |
| Tony Pena |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Brad Penny |   | sp | 30 | 17 | 0 | .000 | 0 | 5 | .294 | 85 | 5.0 | 11 | 5 | .455 |
| Joel Peralta | MID | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 8 | .500 |
| Troy Percival |   | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 |
| Chris Perez | LON | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Odalis Perez* |   | sp | 31 | 30 | 0 | .000 | 0 | 14 | .467 | 120 | 4.0 | 14 | 3 | .214 |
| Oliver Perez* | WIZ | sp | 26 | 34 | 0 | .000 | 0 | 17 | .500 | 165 | 4.9 | 32 | 12 | .375 |
| Rafael Perez* | BT | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 |
| Glen Perkins* | BON | sp | 25 | 26 | 0 | .000 | 0 | 12 | .462 | 160 | 6.2 | 13 | 4 | .308 |
| Yusmeiro Petit | WIZ | mr | 23 | 8 | 0 | .000 | 0 | 3 | .375 | 40 | 5.0 | 5 | 0 | .000 |
| Andy Pettitte* |   | sp | 36 | 33 | 0 | .000 | 0 | 18 | .545 | 146 | 4.4 | 14 | 3 | .214 |
| Adam Pettyjohn* |   | mr | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 2 | 2 | 1.000 |
| Carmen Pignatiello* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Joel Pineiro | CCL | sp | 29 | 25 | 0 | .000 | 0 | 12 | .480 | 127 | 5.1 | 18 | 6 | .333 |
| Renyel Pinto* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 11 | .407 |
| Sidney Ponson |   | sp | 31 | 24 | 1 | .042 | 0 | 10 | .417 | 156 | 6.5 | 17 | 6 | .353 |
| David Price* |   | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 3 | 1 | .333 |
| Scott Proctor |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 6 | .273 |
| David Purcey* |   | sp | 26 | 12 | 1 | .083 | 0 | 6 | .500 | 42 | 3.5 | 4 | 1 | .250 |
| J.J. Putz | MID | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Chad Qualls | BON | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Edwar Ramirez | EDG | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 |
| Elizardo Ramirez |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Horacio Ramirez* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 |
| Ramon Ramirez | LON | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 10 | .313 |
| Ramon Ramirez |   | sp | 25 | 4 | 0 | .000 | 0 | 3 | .750 | 23 | 5.8 | 0 | 0 | .000 |
| Clay Rapada* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 5 | .208 |
| Darrell Rasner |   | sp | 27 | 20 | 0 | .000 | 0 | 6 | .300 | 105 | 5.3 | 18 | 10 | .556 |
| Jon Rauch |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Tim Redding |   | sp | 30 | 33 | 1 | .030 | 0 | 14 | .424 | 162 | 4.9 | 22 | 13 | .591 |
| Mark Redman* |   | sp | 34 | 9 | 0 | .000 | 0 | 1 | .111 | 45 | 5.0 | 7 | 1 | .143 |
| Steven Register |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chad Reineke |   | sp | 26 | 3 | 0 | .000 | 0 | 1 | .333 | 18 | 6.0 | 0 | 0 | .000 |
| Chris Resop |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Al Reyes |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Anthony Reyes |   | sp | 26 | 6 | 0 | .000 | 0 | 4 | .667 | 31 | 5.2 | 1 | 0 | .000 |
| Dennys Reyes* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 5 | .119 |
| Jo-Jo Reyes* |   | sp | 23 | 22 | 0 | .000 | 0 | 7 | .318 | 84 | 3.8 | 24 | 7 | .292 |
| Greg Reynolds |   | sp | 22 | 13 | 0 | .000 | 0 | 4 | .308 | 68 | 5.2 | 11 | 3 | .273 |
| Arthur Rhodes* | OTR | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 5 | .143 |
| Clayton Richard* |   | sp | 24 | 8 | 0 | .000 | 0 | 3 | .375 | 30 | 3.8 | 10 | 7 | .700 |
| Scott Richmond |   | sp | 28 | 5 | 1 | .200 | 1 | 1 | .200 | 9 | 1.8 | 1 | 0 | .000 |
| Jeff Ridgway* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Juan Rincon |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 |
| Ricardo Rincon* |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Royce Ring* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 |
| David Riske |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 |
| Mariano Rivera | ROK | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Saul Rivera |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 |
| Connor Robertson |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| David Robertson |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 |
| Nate Robertson* |   | sp | 30 | 28 | 0 | .000 | 0 | 9 | .321 | 145 | 5.2 | 30 | 13 | .433 |
| Fernando Rodney | OTR | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Francisco Rodriguez | BON | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Wandy Rodriguez* | BT | sp | 29 | 25 | 0 | .000 | 0 | 10 | .400 | 111 | 4.4 | 17 | 2 | .118 |
| Josh Roenicke |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Kenny Rogers* |   | sp | 43 | 30 | 0 | .000 | 0 | 14 | .467 | 133 | 4.4 | 25 | 12 | .480 |
| J.C. Romero* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 4 | .154 |
| Sergio Romo |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Carlos Rosa |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Leo Rosales |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Ryan Rowland-Smith* | CRH | mr | 25 | 12 | 0 | .000 | 0 | 8 | .667 | 47 | 3.9 | 24 | 11 | .458 |
| Rich Rundles* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Josh Rupe |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 |
| Glendon Rusch* |   | mr | 33 | 9 | 0 | .000 | 0 | 2 | .222 | 41 | 4.6 | 20 | 8 | .400 |
| Adam Russell |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 |
| B.J. Ryan* | CRH | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Jae Kuk Ryu |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Kirk Saarloos |   | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 5 | 0 | .000 |
| C.C. Sabathia* | CRH | sp | 27 | 35 | 10 | .286 | 5 | 25 | .714 | 162 | 4.6 | 12 | 5 | .417 |
| Billy Sadler |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 |
| Takashi Saito | Pal | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Juan Salas |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Marino Salas |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Jeff Samardzija |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 |
| Chris Sampson | MUL | mr | 30 | 11 | 0 | .000 | 0 | 4 | .364 | 62 | 5.6 | 22 | 5 | .227 |
| Brian Sanches |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Anibal Sanchez | MAD | sp | 24 | 10 | 0 | .000 | 0 | 2 | .200 | 53 | 5.3 | 10 | 1 | .100 |
| Duaner Sanchez | BT | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 10 | .400 |
| Humberto Sanchez |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jonathan Sanchez* | MAD | sp | 25 | 29 | 0 | .000 | 0 | 13 | .448 | 136 | 4.7 | 22 | 10 | .455 |
| Romulo Sanchez |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Ervin Santana | BON | sp | 25 | 32 | 2 | .063 | 1 | 22 | .688 | 136 | 4.3 | 10 | 4 | .400 |
| Johan Santana* | ROK | sp | 29 | 34 | 3 | .088 | 2 | 28 | .824 | 161 | 4.7 | 15 | 5 | .333 |
| Dennis Sarfate |   | mr | 27 | 4 | 0 | .000 | 0 | 0 | .000 | 19 | 4.8 | 33 | 14 | .424 |
| Joe Saunders* | MID | sp | 27 | 31 | 1 | .032 | 0 | 22 | .710 | 135 | 4.4 | 13 | 6 | .462 |
| Max Scherzer | LON | mr | 23 | 7 | 0 | .000 | 0 | 3 | .429 | 16 | 2.3 | 2 | 1 | .500 |
| Scott Schoeneweis* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 5 | .167 |
| Chris Schroder |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 |
| Rudy Seanez | TON | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Bobby Seay* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 11 | .324 |
| Alex Serrano |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Ben Sheets | CRH | sp | 29 | 31 | 5 | .161 | 3 | 18 | .581 | 138 | 4.5 | 10 | 0 | .000 |
| Steven Shell | CRH | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 |
| George Sherrill* | ROK | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| James Shields | BON | sp | 26 | 33 | 3 | .091 | 2 | 22 | .667 | 163 | 4.9 | 19 | 8 | .421 |
| Scot Shields | ROK | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 9 | .818 |
| Brian Shouse* | OTR | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 7 | .269 |
| Carlos Silva |   | sp | 29 | 28 | 1 | .036 | 0 | 10 | .357 | 125 | 4.5 | 15 | 5 | .333 |
| Alfredo Simon |   | mr | 27 | 1 | 0 | .000 | 0 | 1 | 1.000 | 5 | 5.0 | 1 | 0 | .000 |
| Doug Slaten* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 8 | .444 |
| Brian Slocum |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Kevin Slowey |   | sp | 24 | 27 | 3 | .111 | 2 | 13 | .481 | 138 | 5.1 | 17 | 3 | .176 |
| Chris Smith |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Greg Smith* |   | sp | 24 | 32 | 2 | .063 | 0 | 13 | .406 | 100 | 3.1 | 20 | 10 | .500 |
| Joe Smith | MAD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 13 | .342 |
| John Smoltz |   | sp | 41 | 5 | 0 | .000 | 0 | 2 | .400 | 24 | 4.8 | 0 | 0 | .000 |
| Ian Snell |   | sp | 26 | 31 | 0 | .000 | 0 | 13 | .419 | 147 | 4.7 | 14 | 4 | .286 |
| Kyle Snyder |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Andy Sonnanstine | EDG | sp | 25 | 32 | 1 | .031 | 1 | 13 | .406 | 149 | 4.7 | 14 | 3 | .214 |
| Joakim Soria | BON | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Rafael Soriano | GEO | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jorge Sosa |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeremy Sowers* |   | sp | 25 | 22 | 0 | .000 | 0 | 7 | .318 | 94 | 4.3 | 8 | 4 | .500 |
| Justin Speier |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 |
| Ryan Speier | MUL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 |
| Levale Speigner |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Russ Springer | WIZ | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Mitch Stetter* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 0 | .000 |
| Phil Stockman |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Brian Stokes |   | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 8 | 0 | .000 |
| Huston Street | GEO | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 |
| Eric Stults* |   | sp | 28 | 7 | 1 | .143 | 1 | 3 | .429 | 40 | 5.7 | 9 | 4 | .444 |
| Tanyon Sturtze |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeff Suppan |   | sp | 33 | 31 | 0 | .000 | 0 | 14 | .452 | 144 | 4.6 | 19 | 5 | .263 |
| R.J. Swindle* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Mitch Talbot |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 5 | 1 | .200 |
| Brian Tallet* | EDG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 |
| Taylor Tankersley* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 |
| Jack Taschner* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 52 | 7 | .135 |
| Ty Taubenheim |   | sp | 25 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 |
| Julian Tavarez |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 |
| Robinson Tejeda | OTR | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 10 | 5 | .500 |
| Joe Thatcher* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 |
| Justin Thomas* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Brad Thompson |   | mr | 26 | 6 | 0 | .000 | 0 | 1 | .167 | 27 | 4.5 | 10 | 4 | .400 |
| Daryl Thompson |   | sp | 22 | 3 | 0 | .000 | 0 | 0 | .000 | 11 | 3.7 | 2 | 2 | 1.000 |
| Rich Thompson |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Matt Thornton* | CRH | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 |
| Erick Threets* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Timlin |   | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 |
| Brett Tomko |   | sp | 35 | 10 | 0 | .000 | 0 | 3 | .300 | 38 | 3.8 | 9 | 4 | .444 |
| Salomon Torres | MUL | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Billy Traber* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 |
| Steve Trachsel |   | sp | 37 | 8 | 0 | .000 | 0 | 2 | .250 | 33 | 4.1 | 10 | 5 | .500 |
| Ramon Troncoso |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Ryan Tucker |   | mr | 21 | 6 | 0 | .000 | 0 | 1 | .167 | 35 | 5.8 | 3 | 2 | .667 |
| Derrick Turnbow |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Merkin Valdez |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 11 | 2 | .182 |
| Jose Valverde | WIZ | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| John Van Benschoten |   | sp | 28 | 5 | 0 | .000 | 0 | 0 | .000 | 29 | 5.8 | 6 | 0 | .000 |
| Rick VandenHurk |   | sp | 23 | 4 | 0 | .000 | 0 | 0 | .000 | 17 | 4.3 | 7 | 3 | .429 |
| Claudio Vargas |   | mr | 30 | 4 | 0 | .000 | 0 | 2 | .500 | 22 | 5.5 | 4 | 3 | .750 |
| Javier Vazquez | Pal | sp | 31 | 33 | 1 | .030 | 0 | 17 | .515 | 161 | 4.9 | 23 | 10 | .435 |
| Jose Veras |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 |
| Justin Verlander | COP | sp | 25 | 33 | 1 | .030 | 0 | 13 | .394 | 140 | 4.2 | 28 | 15 | .536 |
| Carlos Villanueva |   | mr | 24 | 9 | 0 | .000 | 0 | 3 | .333 | 43 | 4.8 | 21 | 4 | .190 |
| Oscar Villarreal |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Ron Villone* |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 3 | .075 |
| Luis Vizcaino |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Edinson Volquez | LON | sp | 24 | 32 | 0 | .000 | 0 | 20 | .625 | 165 | 5.2 | 12 | 3 | .250 |
| Chris Volstad | MAD | sp | 21 | 14 | 0 | .000 | 0 | 9 | .643 | 50 | 3.6 | 8 | 4 | .500 |
| Cory Wade | Pal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 |
| Doug Waechter |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 |
| Billy Wagner* | BT | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Adam Wainwright | MAD | sp | 26 | 20 | 1 | .050 | 0 | 12 | .600 | 115 | 5.8 | 9 | 1 | .111 |
| Tim Wakefield | OTR | sp | 41 | 30 | 1 | .033 | 0 | 18 | .600 | 151 | 5.0 | 14 | 8 | .571 |
| Jamie Walker* | OTR | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 6 | .207 |
| Tyler Walker |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 9 | .474 |
| Les Walrond* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Chien-Ming Wang | MID | sp | 28 | 15 | 1 | .067 | 0 | 9 | .600 | 80 | 5.3 | 9 | 4 | .444 |
| Jarrod Washburn* |   | sp | 33 | 26 | 1 | .038 | 0 | 14 | .538 | 96 | 3.7 | 20 | 8 | .400 |
| Ehren Wassermann |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 9 | .643 |
| Chris Waters* |   | sp | 27 | 11 | 1 | .091 | 1 | 4 | .364 | 52 | 4.7 | 12 | 3 | .250 |
| David Weathers |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Jered Weaver | OTR | sp | 25 | 30 | 0 | .000 | 0 | 14 | .467 | 129 | 4.3 | 19 | 10 | .526 |
| Brandon Webb | TON | sp | 29 | 34 | 3 | .088 | 1 | 24 | .706 | 153 | 4.5 | 11 | 4 | .364 |
| Todd Wellemeyer | Pal | sp | 29 | 32 | 0 | .000 | 0 | 17 | .531 | 154 | 4.8 | 9 | 4 | .444 |
| Jared Wells |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Kip Wells |   | mr | 31 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 15 | 5 | .333 |
| Randy Wells |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jake Westbrook |   | sp | 30 | 5 | 1 | .200 | 0 | 4 | .800 | 14 | 2.8 | 4 | 0 | .000 |
| Dan Wheeler | Pal | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Bill White* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Dontrelle Willis* |   | sp | 26 | 7 | 0 | .000 | 0 | 0 | .000 | 31 | 4.4 | 10 | 7 | .700 |
| Brian Wilson | MUL | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| C.J. Wilson* | ROK | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Matt Wise |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Randy Wolf* | CCL | sp | 31 | 33 | 1 | .030 | 1 | 18 | .545 | 140 | 4.2 | 18 | 9 | .500 |
| Brian Wolfe |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 |
| Kerry Wood | MUL | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jake Woods* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Mark Worrell |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Jamey Wright |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 12 | .480 |
| Wesley Wright* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 7 | .219 |
| Michael Wuertz | ROK | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 7 | .350 |
| Keiichi Yabu |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 12 | .364 |
| Yasuhiko Yabuta |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 |
| Tyler Yates |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 |
| Chris Young | COP | sp | 29 | 18 | 1 | .056 | 0 | 9 | .500 | 72 | 4.0 | 10 | 6 | .600 |
| Carlos Zambrano | CCL | sp | 27 | 30 | 1 | .033 | 1 | 17 | .567 | 172 | 5.7 | 14 | 3 | .214 |
| Brad Ziegler | CRH | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Charlie Zink |   | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 19 | 19.0 | 2 | 2 | 1.000 |
| Barry Zito* |   | sp | 30 | 32 | 0 | .000 | 0 | 15 | .469 | 114 | 3.6 | 19 | 6 | .316 |
| Joel Zumaya |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF |
| David Aardsma | EDG | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 4 | 32 | 13 | .406 | 47 | 47 | 7 |
| Jeremy Accardo |   | mr | 26 | 6 | 4 | .667 | 2 | .333 | 2 | 10 | 3 | .300 | 16 | 16 | 6 |
| Alfredo Aceves |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 6 | 2 | 1 |
| Manny Acosta |   | mr | 27 | 5 | 3 | .600 | 2 | .400 | 4 | 13 | 2 | .154 | 46 | 46 | 22 |
| Mike Adams | MUL | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 10 | 19 | 6 | .316 | 54 | 54 | 11 |
| Nick Adenhart |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Jon Adkins |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 4 | 4 | 0 |
| Jeremy Affeldt* | CRH | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 5 | 36 | 12 | .333 | 74 | 74 | 20 |
| Jonathan Albaladejo |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 7 | 7 | 2 |
| Matt Albers |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 6 | 18 | 4 | .222 | 28 | 25 | 5 |
| Greg Aquino |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 9 | 9 | 5 |
| Alberto Arias |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 3 | .231 | 15 | 13 | 4 |
| Tony Armas |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 2 | 1 |
| Jose Arredondo | COP | mr | 24 | 7 | 0 | .000 | 7 | 1.000 | 16 | 31 | 14 | .452 | 52 | 52 | 10 |
| Bronson Arroyo | BT | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jose Ascanio |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 6 | 1 |
| Luis Ayala |   | mr | 30 | 15 | 9 | .600 | 6 | .400 | 19 | 25 | 9 | .360 | 81 | 81 | 25 |
| Brandon Backe |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Burke Badenhop |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 13 | 5 | 2 |
| Cha Seung Baek |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 4 | .571 | 32 | 11 | 2 |
| Homer Bailey |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Scott Baker | BON | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| John Bale* |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 2 | 5 | 0 | .000 | 13 | 10 | 1 |
| Collin Balester |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Grant Balfour | COP | mr | 30 | 5 | 4 | .800 | 1 | .200 | 14 | 44 | 9 | .205 | 51 | 51 | 12 |
| Josh Banks |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 3 | 1 |
| Brian Bannister |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jimmy Barthmaier |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Brian Bass |   | mr | 26 | 2 | 1 | .500 | 1 | .500 | 4 | 42 | 12 | .286 | 49 | 45 | 14 |
| Miguel Batista |   | mr | 37 | 4 | 1 | .250 | 3 | .750 | 4 | 17 | 9 | .529 | 44 | 24 | 9 |
| Rick Bauer |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 2 |
| Denny Bautista |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 10 | 21 | 6 | .286 | 51 | 51 | 8 |
| Yorman Bazardo |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 3 |
| T.J. Beam |   | mr | 27 | 2 | 1 | .500 | 1 | .500 | 2 | 21 | 7 | .333 | 32 | 32 | 8 |
| Josh Beckett | Pal | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Erik Bedard* | GEO | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Joe Beimel* |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 12 | 60 | 20 | .333 | 71 | 71 | 10 |
| Matt Belisle |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Heath Bell | MUL | mr | 30 | 7 | 0 | .000 | 7 | 1.000 | 23 | 11 | 4 | .364 | 74 | 74 | 8 |
| Francis Beltran |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 3 | .375 | 11 | 11 | 4 |
| Armando Benitez |   | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 2 | 3 | 1 | .333 | 8 | 8 | 2 |
| Jeff Bennett | TON | mr | 28 | 5 | 3 | .600 | 2 | .400 | 16 | 42 | 14 | .333 | 72 | 68 | 12 |
| Joaquin Benoit | OTR | mr | 30 | 4 | 1 | .250 | 3 | .750 | 13 | 14 | 3 | .214 | 44 | 44 | 8 |
| Jason Bergmann |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 30 | 8 | 1 |
| Rafael Betancourt | GEO | mr | 33 | 9 | 4 | .444 | 5 | .556 | 12 | 33 | 12 | .364 | 69 | 69 | 20 |
| Randor Bierd |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 39 | 21 | .538 | 29 | 29 | 8 |
| Chad Billingsley | TON | sp | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 0 | 0 | .000 | 35 | 3 | 1 |
| Kurt Birkins* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 6 | 6 | 2 |
| Nick Blackburn |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Joe Blanton |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jerry Blevins* |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 6 | 24 | 5 | .208 | 36 | 36 | 8 |
| Mitchell Boggs |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 1 |
| Jeremy Bonderman |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| Eddie Bonine |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Boof Bonser |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 2 | 19 | 3 | .158 | 47 | 35 | 9 |
| Chris Bootcheck |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 2 | .400 | 10 | 10 | 4 |
| Dave Borkowski |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 1 | 11 | 4 | .364 | 26 | 26 | 5 |
| Joe Borowski |   | cl | 37 | 10 | 6 | .600 | 4 | .400 | 0 | 0 | 0 | .000 | 18 | 18 | 14 |
| Michael Bowden |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Cedrick Bowers* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 5 | 5 | 3 |
| Micah Bowie* |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 1 | .111 | 10 | 10 | 1 |
| Blaine Boyer |   | mr | 26 | 7 | 1 | .143 | 6 | .857 | 14 | 26 | 11 | .423 | 76 | 76 | 18 |
| Dallas Braden* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 19 | 9 | 7 |
| Chad Bradford | MID | mr | 33 | 2 | 0 | .000 | 2 | 1.000 | 21 | 49 | 18 | .367 | 68 | 68 | 9 |
| Bill Bray* |   | mr | 25 | 4 | 0 | .000 | 4 | 1.000 | 9 | 48 | 14 | .292 | 63 | 63 | 11 |
| Yhency Brazoban |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Craig Breslow* | MID | mr | 27 | 2 | 1 | .500 | 1 | .500 | 5 | 47 | 9 | .191 | 49 | 49 | 13 |
| Chris Britton |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 15 | 15 | 14 |
| Lance Broadway |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 7 | 6 | 4 |
| Doug Brocail |   | mr | 41 | 5 | 2 | .400 | 3 | .600 | 22 | 30 | 8 | .267 | 72 | 72 | 21 |
| Andrew Brown |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 2 | 11 | 6 | .545 | 31 | 31 | 13 |
| Jonathan Broxton | CCL | mr | 24 | 22 | 14 | .636 | 8 | .364 | 13 | 31 | 7 | .226 | 70 | 70 | 32 |
| Brian Bruney |   | mr | 26 | 2 | 1 | .500 | 1 | .500 | 13 | 24 | 10 | .417 | 32 | 31 | 5 |
| Clay Buchholz | COP | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 0 |
| Taylor Buchholz | TON | mr | 26 | 3 | 1 | .333 | 2 | .667 | 21 | 10 | 1 | .100 | 63 | 63 | 19 |
| Billy Buckner |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 10 | 10 | 5 |
| Mark Buehrle* | BON | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Francisley Bueno* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Ryan Bukvich |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 4 | 4 | 0 |
| Jason Bulger |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 14 | 14 | 7 |
| Bryan Bullington |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 0 |
| A.J. Burnett | TON | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 1 | 1 |
| Sean Burnett* | WIZ | mr | 25 | 0 | 0 | .000 | 0 | .000 | 8 | 44 | 13 | .295 | 58 | 58 | 16 |
| Brian Burres* |   | sp | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 4 | .500 | 31 | 9 | 1 |
| Jared Burton | MAD | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 11 | 17 | 9 | .529 | 54 | 54 | 12 |
| Dave Bush | OTR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 31 | 2 | 0 |
| Paul Byrd |   | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Tim Byrdak* |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 9 | 32 | 6 | .188 | 59 | 59 | 9 |
| Daniel Cabrera |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Fernando Cabrera |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 21 | 14 | .667 | 22 | 22 | 8 |
| Matt Cain | LON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Kiko Calero |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 5 | 5 | 3 |
| Kevin Cameron |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 10 | 10 | 4 |
| Shawn Camp |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 7 | 26 | 9 | .346 | 40 | 40 | 16 |
| Jorge Campillo | WIZ | sp | 29 | 0 | 0 | .000 | 0 | .000 | 4 | 6 | 4 | .667 | 39 | 14 | 3 |
| Jose Capellan |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Matt Capps | MUL | cl | 24 | 26 | 21 | .808 | 5 | .192 | 0 | 5 | 2 | .400 | 49 | 49 | 39 |
| Jesse Carlson* | BON | mr | 27 | 3 | 2 | .667 | 1 | .333 | 19 | 49 | 9 | .184 | 69 | 69 | 10 |
| Buddy Carlyle | LON | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 0 | 36 | 8 | .222 | 45 | 45 | 5 |
| Fausto Carmona |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Andrew Carpenter |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Chris Carpenter | TON | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 0 |
| D.J. Carrasco |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 7 | 32 | 12 | .375 | 31 | 31 | 6 |
| Santiago Casilla | OTR | mr | 27 | 3 | 2 | .667 | 1 | .333 | 8 | 31 | 14 | .452 | 51 | 51 | 9 |
| Jack Cassel |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 9 | 6 | 1 |
| Alberto Castillo* |   | mr | 32 | 2 | 0 | .000 | 2 | 1.000 | 0 | 33 | 12 | .364 | 28 | 28 | 5 |
| Shawn Chacon |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Joba Chamberlain | BT | mr | 22 | 1 | 0 | .000 | 1 | 1.000 | 19 | 10 | 2 | .200 | 42 | 30 | 5 |
| Jesse Chavez |   | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 1 | 5 | 3 | .600 | 15 | 15 | 6 |
| Rocky Cherry |   | mr | 28 | 3 | 1 | .333 | 2 | .667 | 2 | 12 | 3 | .250 | 18 | 18 | 4 |
| Matt Chico* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 3 | 0 |
| Vinnie Chulk |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 2 | 25 | 7 | .280 | 27 | 27 | 9 |
| Tyler Clippard |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Todd Coffey |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 3 | 9 | 2 | .222 | 26 | 26 | 9 |
| Phil Coke* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 5 | 3 | 0 | .000 | 12 | 12 | 0 |
| Jesus Colome |   | mr | 30 | 3 | 0 | .000 | 3 | 1.000 | 1 | 29 | 11 | .379 | 61 | 61 | 25 |
| Bartolo Colon |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Clay Condrey |   | mr | 32 | 2 | 1 | .500 | 1 | .500 | 1 | 21 | 6 | .286 | 56 | 56 | 30 |
| Jose Contreras |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Aaron Cook | MAD | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Roy Corcoran | EDG | mr | 28 | 6 | 3 | .500 | 3 | .500 | 8 | 28 | 13 | .464 | 50 | 50 | 13 |
| Chad Cordero |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 6 | 6 | 2 |
| Francisco Cordero | CRH | cl | 33 | 40 | 34 | .850 | 6 | .150 | 0 | 15 | 9 | .600 | 72 | 72 | 63 |
| Bryan Corey |   | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 4 | 19 | 7 | .368 | 46 | 46 | 10 |
| Lance Cormier |   | mr | 27 | 5 | 1 | .200 | 4 | .800 | 3 | 47 | 16 | .340 | 45 | 44 | 10 |
| Manuel Corpas |   | mr | 25 | 13 | 4 | .308 | 9 | .692 | 19 | 21 | 9 | .429 | 76 | 76 | 20 |
| Kevin Correia | MUL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 1 | .167 | 25 | 6 | 2 |
| Neal Cotts* | CRH | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 10 | 33 | 7 | .212 | 50 | 50 | 7 |
| Jesse Crain | BON | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 17 | 42 | 11 | .262 | 66 | 66 | 14 |
| Francisco Cruceta |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 1 | 8 | 6 | .750 | 13 | 13 | 8 |
| Juan Cruz | TON | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 8 | 27 | 12 | .444 | 57 | 57 | 10 |
| Johnny Cueto | Pal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| John Danks* | EDG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Kyle Davies |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| Doug Davis* |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Jason Davis |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 0 | .000 | 14 | 10 | 2 |
| Eulogio De La Cruz |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 6 | 5 | 1 |
| Jorge De La Rosa* | MUL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 28 | 5 | 0 |
| Valerio de los Santos* |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Manny Delcarmen | GEO | mr | 26 | 5 | 2 | .400 | 3 | .600 | 18 | 45 | 16 | .356 | 73 | 73 | 16 |
| Jesus Delgado |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Ryan Dempster | CRH | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Matt DeSalvo |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 |
| Elmer Dessens |   | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 4 | 4 | 1 |
| Joey Devine | BT | mr | 24 | 2 | 1 | .500 | 1 | .500 | 11 | 22 | 7 | .318 | 42 | 42 | 10 |
| Joselo Diaz |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| R.A. Dickey | OTR | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 4 | .400 | 32 | 18 | 9 |
| Mark DiFelice |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 2 | .286 | 15 | 15 | 5 |
| Tim Dillard |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 2 | .286 | 13 | 13 | 5 |
| Lenny DiNardo* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 11 | 9 | 8 |
| Scott Dohmann |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 3 | .250 | 12 | 12 | 6 |
| Freddy Dolsi |   | mr | 25 | 3 | 2 | .667 | 1 | .333 | 7 | 34 | 11 | .324 | 42 | 42 | 13 |
| Brendan Donnelly |   | mr | 36 | 0 | 0 | .000 | 0 | .000 | 4 | 0 | 0 | .000 | 15 | 15 | 3 |
| Octavio Dotel |   | mr | 34 | 5 | 1 | .200 | 4 | .800 | 21 | 43 | 12 | .279 | 72 | 72 | 10 |
| Scott Downs* | EDG | mr | 32 | 9 | 5 | .556 | 4 | .444 | 24 | 28 | 14 | .500 | 66 | 66 | 14 |
| Justin Duchscherer | COP | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Brandon Duckworth |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Zach Duke* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Phil Dumatrait* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 4 | .571 | 21 | 10 | 4 |
| Chad Durbin | MAD | mr | 30 | 8 | 1 | .125 | 7 | .875 | 18 | 49 | 16 | .327 | 71 | 71 | 12 |
| Adam Eaton |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 2 | 0 |
| Mike Ekstrom |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 2 | .286 | 8 | 8 | 1 |
| Scott Elarton |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 8 | 8 | 4 |
| Scott Elbert* |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 2 | 5 | 1 | .200 | 10 | 10 | 1 |
| Alan Embree* |   | mr | 38 | 5 | 0 | .000 | 5 | 1.000 | 19 | 45 | 9 | .200 | 70 | 70 | 11 |
| Geno Espineli* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 15 | 15 | 5 |
| Shawn Estes* |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 9 | 1 | 0 |
| Marco Estrada |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 4 | 12 | 6 | .500 | 11 | 11 | 3 |
| Dana Eveland* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Scott Eyre* |   | mr | 36 | 2 | 0 | .000 | 2 | 1.000 | 8 | 36 | 7 | .194 | 38 | 38 | 3 |
| Brian Falkenborg |   | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 3 | 20 | 8 | .400 | 25 | 25 | 8 |
| Kyle Farnsworth |   | mr | 32 | 4 | 1 | .250 | 3 | .750 | 14 | 14 | 7 | .500 | 61 | 61 | 11 |
| Ryan Feierabend* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Scott Feldman | MID | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 28 | 3 | 2 |
| Pedro Feliciano* | MAD | mr | 31 | 4 | 2 | .500 | 2 | .500 | 21 | 71 | 20 | .282 | 86 | 86 | 14 |
| Nelson Figueroa |   | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 0 | 6 | 5 | .833 | 16 | 10 | 2 |
| Randy Flores* |   | mr | 32 | 3 | 1 | .333 | 2 | .667 | 14 | 27 | 11 | .407 | 43 | 43 | 3 |
| Gavin Floyd | TON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Josh Fogg |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 22 | 8 | 3 |
| Casey Fossum* |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 7 | 34 | 10 | .294 | 31 | 31 | 9 |
| Keith Foulke |   | mr | 35 | 2 | 1 | .500 | 1 | .500 | 8 | 9 | 5 | .556 | 31 | 31 | 9 |
| Chad Fox |   | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 3 | 3 | 1 |
| Jeff Francis* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Frank Francisco | EDG | mr | 28 | 11 | 5 | .455 | 6 | .545 | 14 | 35 | 9 | .257 | 58 | 58 | 18 |
| Ryan Franklin |   | mr | 35 | 25 | 17 | .680 | 8 | .320 | 13 | 22 | 9 | .409 | 74 | 74 | 39 |
| Jason Frasor | MID | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 4 | 32 | 4 | .125 | 49 | 49 | 21 |
| Brian Fuentes* | CCL | cl | 32 | 34 | 30 | .882 | 4 | .118 | 6 | 5 | 3 | .600 | 67 | 67 | 48 |
| Kazuo Fukumori |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 0 |
| Jeff Fulchino |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 12 | 12 | 7 |
| Kason Gabbard* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| Eric Gagne |   | mr | 32 | 17 | 10 | .588 | 7 | .412 | 7 | 7 | 1 | .143 | 50 | 50 | 16 |
| Armando Galarraga |   | sp | 26 | 2 | 0 | .000 | 2 | 1.000 | 0 | 1 | 1 | 1.000 | 30 | 2 | 0 |
| Sean Gallagher |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 23 | 2 | 1 |
| Yovani Gallardo | LON | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Freddy Garcia |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Jaime Garcia* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 3 | 3 | 2 | .667 | 10 | 9 | 4 |
| Lee Gardner |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 7 | 7 | 0 |
| Jon Garland |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Matt Garza | GEO | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Chad Gaudin |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 5 | 16 | 5 | .313 | 50 | 44 | 14 |
| Geoff Geary | TON | mr | 31 | 2 | 0 | .000 | 2 | 1.000 | 12 | 20 | 3 | .150 | 55 | 55 | 8 |
| Josh Geer |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Franklyn German |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 1 | 18 | 10 | .556 | 17 | 17 | 9 |
| Justin Germano |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 12 | 6 | 4 |
| Dan Giese | BON | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 2 | .286 | 20 | 17 | 6 |
| Matt Ginter |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Tom Glavine* |   | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Gary Glover |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 5 | 30 | 7 | .233 | 47 | 47 | 15 |
| Jimmy Gobble* |   | mr | 26 | 2 | 1 | .500 | 1 | .500 | 4 | 28 | 15 | .536 | 39 | 39 | 10 |
| Edgar Gonzalez |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 17 | 11 | 3 |
| Enrique Gonzalez |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 4 | 4 | 3 |
| Gio Gonzalez* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 3 | 3 |
| Mike Gonzalez* |   | cl | 30 | 16 | 14 | .875 | 2 | .125 | 0 | 7 | 2 | .286 | 36 | 36 | 29 |
| Brian Gordon |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 0 |
| Tom Gordon |   | mr | 40 | 3 | 2 | .667 | 1 | .333 | 14 | 12 | 4 | .333 | 34 | 34 | 7 |
| Tom Gorzelanny* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| John Grabow* | TON | mr | 29 | 8 | 4 | .500 | 4 | .500 | 16 | 33 | 8 | .242 | 74 | 74 | 18 |
| Jeff Gray |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 5 | 5 | 2 |
| Sean Green |   | mr | 29 | 4 | 1 | .250 | 3 | .750 | 17 | 49 | 10 | .204 | 72 | 72 | 13 |
| Kevin Gregg | BT | cl | 30 | 38 | 29 | .763 | 9 | .237 | 4 | 15 | 1 | .067 | 72 | 72 | 59 |
| Zack Greinke | COP | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jason Grilli | COP | mr | 31 | 3 | 1 | .333 | 2 | .667 | 5 | 30 | 9 | .300 | 60 | 60 | 16 |
| Eddie Guardado* |   | mr | 37 | 5 | 4 | .800 | 1 | .200 | 25 | 18 | 5 | .278 | 65 | 65 | 14 |
| Matt Guerrier | MID | mr | 29 | 5 | 1 | .200 | 4 | .800 | 20 | 37 | 8 | .216 | 76 | 76 | 15 |
| Carlos Guevara |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 10 | 10 | 6 |
| Jeremy Guthrie | MID | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Angel Guzman |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 5 | 1 |
| Charlie Haeger |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 0 | .000 | 4 | 4 | 1 |
| Roy Halladay | ROK | sp | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 34 | 1 | 0 |
| Cole Hamels* | BT | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jason Hammel | EDG | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 1 | 12 | 8 | .667 | 40 | 35 | 21 |
| Justin Hampson* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 27 | 9 | .333 | 35 | 35 | 8 |
| Mike Hampton* |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Joel Hanrahan | CCL | mr | 26 | 13 | 9 | .692 | 4 | .308 | 3 | 34 | 15 | .441 | 69 | 69 | 34 |
| Devern Hansack |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 4 | 4 | 3 |
| Craig Hansen |   | mr | 24 | 7 | 3 | .429 | 4 | .571 | 7 | 17 | 7 | .412 | 48 | 48 | 15 |
| J.A. Happ* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 8 | 4 | 1 |
| Aaron Harang | GEO | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 1 | 0 |
| Rich Harden | COP | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Dan Haren | LON | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Matt Harrison* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Kevin Hart |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 8 | 4 | .500 | 21 | 21 | 4 |
| LaTroy Hawkins |   | mr | 35 | 2 | 1 | .500 | 1 | .500 | 13 | 17 | 7 | .412 | 57 | 57 | 15 |
| Dirk Hayhurst |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 3 | .375 | 10 | 7 | 3 |
| Aaron Heilman |   | mr | 29 | 8 | 3 | .375 | 5 | .625 | 15 | 37 | 14 | .378 | 78 | 78 | 23 |
| Mark Hendrickson* |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 3 | 20 | 4 | .200 | 36 | 17 | 4 |
| Sean Henn* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 2 |
| Brad Hennessey |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 3 | 1.000 | 17 | 13 | 4 |
| Clay Hensley |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 4 | 9 | 4 | .444 | 32 | 31 | 8 |
| Matt Herges |   | mr | 38 | 6 | 0 | .000 | 6 | 1.000 | 4 | 20 | 11 | .550 | 58 | 58 | 10 |
| Felix Hernandez | ROK | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Fernando Hernandez |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 3 | 3 | 1 |
| Livan Hernandez |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Runelvys Hernandez |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Danny Herrera* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 7 | 7 | 0 |
| Yoslan Herrera |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Rich Hill* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Shawn Hill |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| Mike Hinckley* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 4 | 7 | 1 | .143 | 14 | 14 | 2 |
| Alex Hinshaw* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 4 | 36 | 9 | .250 | 48 | 48 | 12 |
| Jason Hirsh |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 4 | 3 | 1 |
| Luke Hochevar |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Trevor Hoffman | Pal | cl | 40 | 34 | 30 | .882 | 4 | .118 | 0 | 7 | 0 | .000 | 48 | 48 | 42 |
| J.P. Howell* | MID | mr | 25 | 5 | 3 | .600 | 2 | .400 | 14 | 35 | 4 | .114 | 64 | 64 | 9 |
| Bob Howry | WIZ | mr | 34 | 5 | 1 | .200 | 4 | .800 | 15 | 28 | 5 | .179 | 72 | 72 | 27 |
| Tim Hudson | GEO | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 1 | 0 |
| Phil Hughes | COP | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Philip Humber |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 5 | 5 | 2 |
| Tommy Hunter |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Eric Hurley |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Kei Igawa* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 1 |
| Jason Isringhausen |   | cl | 35 | 19 | 12 | .632 | 7 | .368 | 2 | 8 | 2 | .250 | 42 | 42 | 27 |
| Edwin Jackson |   | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 32 | 1 | 0 |
| Zach Jackson* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 11 | 2 | 2 |
| Chuck James* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Bobby Jenks | OTR | cl | 27 | 34 | 30 | .882 | 4 | .118 | 0 | 9 | 2 | .222 | 57 | 57 | 52 |
| Jason Jennings |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Kevin Jepsen |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 4 | 9 | 4 | .444 | 9 | 9 | 0 |
| Cesar Jimenez* |   | mr | 23 | 4 | 0 | .000 | 4 | 1.000 | 5 | 21 | 13 | .619 | 31 | 29 | 8 |
| Kelvin Jimenez |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 15 | 15 | 5 |
| Ubaldo Jimenez | TON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jason Johnson |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 5 | .500 | 16 | 14 | 5 |
| Jim Johnson | GEO | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 19 | 20 | 3 | .150 | 54 | 54 | 18 |
| Josh Johnson | LON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Randy Johnson* | ROK | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Todd Jones |   | cl | 40 | 21 | 18 | .857 | 3 | .143 | 0 | 8 | 3 | .375 | 45 | 45 | 37 |
| Jorge Julio |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 13 | 7 | .538 | 27 | 27 | 11 |
| Jair Jurrjens | WIZ | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Jeff Karstens |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Scott Kazmir* | GEO | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Kyle Kendrick |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 1 |
| Ian Kennedy |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 1 | 1 |
| Logan Kensing |   | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 6 | 31 | 17 | .548 | 48 | 48 | 7 |
| Clayton Kershaw* | MUL | sp | 20 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 22 | 1 | 0 |
| Ray King* |   | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 4 | 9 | 5 | .556 | 12 | 12 | 2 |
| Josh Kinney |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 7 | 1 |
| Brandon Knight |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 2 | 0 |
| Masa Kobayashi |   | mr | 34 | 9 | 6 | .667 | 3 | .333 | 2 | 16 | 7 | .438 | 57 | 57 | 31 |
| Bobby Korecky |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 0 | .000 | 16 | 16 | 9 |
| Eddie Kunz |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 0 |
| Hong-Chih Kuo* | Pal | mr | 26 | 4 | 1 | .250 | 3 | .750 | 13 | 20 | 2 | .100 | 42 | 39 | 10 |
| Hiroki Kuroda | WIZ | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| John Lackey | COP | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Aaron Laffey* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 |
| Chris Lambert |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 8 | 5 | 1 |
| John Lannan* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Brandon League |   | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 5 | 15 | 5 | .333 | 31 | 31 | 8 |
| Wade LeBlanc* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 0 |
| Wil Ledezma* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 17 | 6 | .353 | 28 | 22 | 8 |
| Cliff Lee* | MID | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Jon Lester* | EDG | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jensen Lewis |   | cl | 24 | 14 | 13 | .929 | 1 | .071 | 4 | 34 | 12 | .353 | 51 | 51 | 28 |
| Scott Lewis* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Brad Lidge | Pal | cl | 31 | 41 | 41 | 1.000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 72 | 72 | 61 |
| Jon Lieber |   | mr | 38 | 1 | 0 | .000 | 1 | 1.000 | 3 | 3 | 2 | .667 | 26 | 25 | 7 |
| Ted Lilly* | OTR | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Tim Lincecum | WIZ | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 0 |
| Mike Lincoln |   | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 10 | 49 | 12 | .245 | 64 | 64 | 12 |
| Matt Lindstrom |   | mr | 28 | 6 | 5 | .833 | 1 | .167 | 14 | 18 | 2 | .111 | 66 | 66 | 27 |
| Scott Linebrink | EDG | mr | 31 | 4 | 1 | .250 | 3 | .750 | 19 | 10 | 2 | .200 | 50 | 50 | 13 |
| Francisco Liriano* | ROK | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Jesse Litsch | EDG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 1 | 0 |
| Wes Littleton |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 15 | 9 | .600 | 12 | 12 | 4 |
| Radhames Liz |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| Esteban Loaiza |   | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 10 | 7 | 5 |
| Kameron Loe |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 2 | 13 | 7 | .538 | 14 | 14 | 4 |
| Adam Loewen* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 2 | .667 | 7 | 3 | 0 |
| Boone Logan* |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 3 | 44 | 12 | .273 | 55 | 55 | 12 |
| Kyle Lohse | CCL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Braden Looper |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Aquilino Lopez |   | mr | 33 | 2 | 0 | .000 | 2 | 1.000 | 4 | 57 | 29 | .509 | 48 | 48 | 18 |
| Javier Lopez* | OTR | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 10 | 46 | 12 | .261 | 70 | 70 | 10 |
| Shane Loux |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 7 | 7 | 5 |
| Derek Lowe | BON | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Mark Lowe |   | mr | 25 | 5 | 1 | .200 | 4 | .800 | 1 | 32 | 7 | .219 | 57 | 57 | 19 |
| Devon Lowery |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 5 | 2 |
| Brandon Lyon | Pal | cl | 28 | 31 | 26 | .839 | 5 | .161 | 3 | 5 | 4 | .800 | 61 | 61 | 50 |
| Mike MacDougal |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 2 | .222 | 16 | 16 | 8 |
| Greg Maddux | Pal | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Warner Madrigal |   | mr | 24 | 4 | 1 | .250 | 3 | .750 | 4 | 21 | 9 | .429 | 31 | 30 | 10 |
| Ryan Madson | CCL | mr | 27 | 4 | 1 | .250 | 3 | .750 | 17 | 37 | 13 | .351 | 76 | 76 | 14 |
| Ron Mahay* |   | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 22 | 47 | 16 | .340 | 57 | 57 | 3 |
| Paul Maholm* | MAD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| John Maine | BT | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Gary Majewski |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 2 | 37 | 14 | .378 | 37 | 37 | 8 |
| Charlie Manning* |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 7 | 35 | 8 | .229 | 57 | 57 | 7 |
| Shaun Marcum | COP | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Carlos Marmol | WIZ | mr | 25 | 9 | 7 | .778 | 2 | .222 | 30 | 47 | 10 | .213 | 82 | 82 | 22 |
| Jason Marquis | CCL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 29 | 1 | 0 |
| Sean Marshall* | LON | mr | 25 | 2 | 1 | .500 | 1 | .500 | 3 | 15 | 5 | .333 | 34 | 27 | 6 |
| Damaso Marte* | WIZ | mr | 33 | 7 | 5 | .714 | 2 | .286 | 25 | 46 | 9 | .196 | 72 | 72 | 10 |
| Pedro Martinez |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Shairon Martis |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 5 | 1 | 0 |
| Nick Masset | GEO | mr | 26 | 3 | 1 | .333 | 2 | .667 | 2 | 26 | 13 | .500 | 42 | 41 | 12 |
| Justin Masterson | OTR | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 3 | 17 | 3 | .176 | 36 | 27 | 6 |
| Tom Mastny |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 0 | 6 | 3 | .500 | 14 | 13 | 4 |
| Doug Mathis |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 4 | 3 |
| Osiris Matos |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 0 | 9 | 3 | .333 | 20 | 20 | 5 |
| Daisuke Matsuzaka | OTR | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Brandon McCarthy | EDG | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Kyle McClellan | MAD | mr | 24 | 6 | 1 | .167 | 5 | .833 | 31 | 33 | 10 | .303 | 68 | 68 | 7 |
| Seth McClung | EDG | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 2 | .667 | 37 | 25 | 10 |
| Bob McCrory |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 8 | 8 | 2 |
| James McDonald |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 4 | 4 | 1 |
| Dustin McGowan |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 |
| Gil Meche | CRH | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Brandon Medders |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 1 | .250 | 18 | 18 | 3 |
| Evan Meek |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 9 | 9 | 7 |
| Jon Meloan |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Luis Mendoza |   | mr | 24 | 2 | 1 | .500 | 1 | .500 | 1 | 13 | 7 | .538 | 25 | 14 | 6 |
| Kent Mercker* |   | mr | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 15 | 15 | 5 |
| Cla Meredith |   | mr | 25 | 7 | 0 | .000 | 7 | 1.000 | 11 | 42 | 21 | .500 | 73 | 73 | 19 |
| Randy Messenger |   | mr | 26 | 2 | 1 | .500 | 1 | .500 | 2 | 10 | 3 | .300 | 13 | 13 | 3 |
| Dan Meyer* |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 11 | 7 | 5 |
| Kam Mickolio |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 6 | 1.000 | 9 | 9 | 5 |
| Jose Mijares* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 2 | 0 | .000 | 10 | 10 | 3 |
| Andrew Miller* | GEO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 1 | .167 | 29 | 9 | 1 |
| Jim Miller |   | mr | 26 | 2 | 1 | .500 | 1 | .500 | 0 | 6 | 4 | .667 | 8 | 8 | 5 |
| Justin Miller |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 7 | 30 | 6 | .200 | 46 | 46 | 8 |
| Trever Miller* |   | mr | 35 | 3 | 2 | .667 | 1 | .333 | 11 | 37 | 6 | .162 | 68 | 68 | 16 |
| Kevin Millwood |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Zach Miner | GEO | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 6 | 26 | 11 | .423 | 45 | 32 | 3 |
| Pat Misch* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 15 | 8 | 6 |
| Garrett Mock | CCL | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 9 | 6 | .667 | 26 | 23 | 5 |
| Brian Moehler |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 31 | 5 | 0 |
| Franklin Morales* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Juan Morillo |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Matt Morris |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Brandon Morrow | CRH | mr | 23 | 12 | 10 | .833 | 2 | .167 | 3 | 13 | 3 | .231 | 45 | 40 | 24 |
| Charlie Morton | LON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 0 |
| Dustin Moseley |   | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 1 | .500 | 12 | 2 | 1 |
| Guillermo Mota |   | mr | 34 | 4 | 1 | .250 | 3 | .750 | 11 | 25 | 5 | .200 | 58 | 58 | 18 |
| Jason Motte |   | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 4 | 10 | 2 | .200 | 12 | 12 | 4 |
| Jamie Moyer* | LON | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Peter Moylan |   | mr | 29 | 2 | 1 | .500 | 1 | .500 | 4 | 2 | 1 | .500 | 7 | 7 | 2 |
| Edward Mujica |   | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 2 | 18 | 6 | .333 | 33 | 33 | 13 |
| Mark Mulder* |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 1 | 1.000 | 3 | 2 | 1 |
| Carlos Muniz |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 2 | 4 | 0 | .000 | 18 | 18 | 8 |
| A.J. Murray* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Neal Musser* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Mike Mussina | MID | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Brett Myers | CRH | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Joe Nathan | WIZ | cl | 33 | 45 | 39 | .867 | 6 | .133 | 0 | 8 | 4 | .500 | 68 | 68 | 57 |
| Joe Nelson | CCL | mr | 33 | 5 | 1 | .200 | 4 | .800 | 11 | 39 | 16 | .410 | 59 | 59 | 20 |
| Pat Neshek | BON | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 6 | 8 | 4 | .500 | 15 | 15 | 3 |
| Josh Newman* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 12 | 12 | 6 |
| Jeff Niemann |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 5 | 3 | 2 |
| Jonathon Niese* |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Fernando Nieve |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 14 | 4 | .286 | 11 | 11 | 1 |
| Dustin Nippert |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 2 | .182 | 20 | 14 | 6 |
| Ricky Nolasco | CCL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 34 | 2 | 0 |
| Hideo Nomo |   | mr | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 3 | 3 | 2 |
| Leo Nunez | ROK | mr | 24 | 3 | 0 | .000 | 3 | 1.000 | 7 | 20 | 11 | .550 | 45 | 45 | 12 |
| Vladimir Nunez |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 3 | .333 | 23 | 23 | 7 |
| Mike O'Connor* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 1 | .333 | 5 | 4 | 0 |
| Darren O'Day | MID | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 17 | 4 | .235 | 30 | 30 | 17 |
| Eric O'Flaherty* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 5 | 4 | .800 | 7 | 7 | 1 |
| Ross Ohlendorf |   | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 4 | 20 | 10 | .500 | 30 | 25 | 3 |
| Will Ohman* | MAD | mr | 30 | 4 | 1 | .250 | 3 | .750 | 24 | 35 | 6 | .171 | 83 | 83 | 16 |
| Hideki Okajima* | COP | mr | 32 | 9 | 1 | .111 | 8 | .889 | 23 | 25 | 13 | .520 | 64 | 64 | 11 |
| Darren Oliver* | GEO | mr | 37 | 2 | 0 | .000 | 2 | 1.000 | 14 | 34 | 14 | .412 | 54 | 54 | 9 |
| Scott Olsen* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Garrett Olson* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Franquelis Osoria |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 19 | 5 | .263 | 43 | 43 | 10 |
| Roy Oswalt | BT | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Josh Outman* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 6 | 2 | 0 |
| Micah Owings | MUL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 22 | 4 | 2 |
| Vicente Padilla |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Matt Palmer |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Jonathan Papelbon | BON | cl | 27 | 46 | 41 | .891 | 5 | .109 | 0 | 30 | 4 | .133 | 67 | 67 | 62 |
| Mike Parisi |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 10 | 6 |
| Chan Ho Park |   | mr | 35 | 5 | 2 | .400 | 3 | .600 | 5 | 21 | 4 | .190 | 54 | 49 | 11 |
| Bobby Parnell |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 6 | 6 | 3 |
| Chad Paronto |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 6 | 6 | 3 |
| James Parr |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Manny Parra* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 3 | 0 |
| John Parrish* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 0 | .000 | 13 | 7 | 1 |
| Scott Patterson |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 2 | .286 | 4 | 4 | 2 |
| David Pauley |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 4 | 3 |
| Carl Pavano |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Jake Peavy | MUL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Jailen Peguero |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 7 | 7 | 0 |
| Mike Pelfrey |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Tony Pena |   | mr | 26 | 7 | 3 | .429 | 4 | .571 | 23 | 14 | 6 | .429 | 72 | 72 | 20 |
| Brad Penny |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 2 | 1 |
| Joel Peralta | MID | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 1 | 31 | 7 | .226 | 40 | 40 | 12 |
| Troy Percival |   | cl | 38 | 32 | 28 | .875 | 4 | .125 | 4 | 2 | 2 | 1.000 | 50 | 50 | 38 |
| Chris Perez | LON | mr | 22 | 11 | 7 | .636 | 4 | .364 | 7 | 11 | 3 | .273 | 41 | 41 | 23 |
| Odalis Perez* |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Oliver Perez* | WIZ | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Rafael Perez* | BT | mr | 26 | 7 | 2 | .286 | 5 | .714 | 25 | 44 | 14 | .318 | 73 | 73 | 14 |
| Glen Perkins* | BON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Yusmeiro Petit | WIZ | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 19 | 11 | 6 |
| Andy Pettitte* |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Adam Pettyjohn* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 1 |
| Carmen Pignatiello* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 2 | 2 | 0 |
| Joel Pineiro | CCL | sp | 29 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 1 | 1 |
| Renyel Pinto* |   | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 18 | 28 | 9 | .321 | 67 | 67 | 11 |
| Sidney Ponson |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 1 | 1 |
| David Price* |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 5 | 4 | 0 |
| Scott Proctor |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 2 | 26 | 12 | .462 | 41 | 41 | 11 |
| David Purcey* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| J.J. Putz | MID | cl | 31 | 23 | 15 | .652 | 8 | .348 | 0 | 9 | 5 | .556 | 47 | 47 | 35 |
| Chad Qualls | BON | mr | 29 | 17 | 9 | .529 | 8 | .471 | 22 | 32 | 11 | .344 | 77 | 77 | 21 |
| Edwar Ramirez | EDG | mr | 27 | 6 | 1 | .167 | 5 | .833 | 6 | 39 | 14 | .359 | 55 | 55 | 16 |
| Elizardo Ramirez |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Horacio Ramirez* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 3 | 16 | 4 | .250 | 32 | 32 | 7 |
| Ramon Ramirez | LON | mr | 26 | 5 | 1 | .200 | 4 | .800 | 21 | 52 | 12 | .231 | 71 | 71 | 15 |
| Ramon Ramirez |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 0 |
| Clay Rapada* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 24 | 2 | .083 | 25 | 25 | 3 |
| Darrell Rasner |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 24 | 4 | 1 |
| Jon Rauch |   | mr | 29 | 24 | 18 | .750 | 6 | .250 | 6 | 14 | 4 | .286 | 74 | 74 | 51 |
| Tim Redding |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Mark Redman* |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 10 | 1 | 1 |
| Steven Register |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 10 | 10 | 5 |
| Chad Reineke |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 |
| Chris Resop |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 4 | .364 | 16 | 16 | 9 |
| Al Reyes |   | mr | 38 | 1 | 0 | .000 | 1 | 1.000 | 2 | 16 | 6 | .375 | 26 | 26 | 6 |
| Anthony Reyes |   | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 2 | 1 | 1 | 1.000 | 16 | 10 | 6 |
| Dennys Reyes* |   | mr | 31 | 3 | 0 | .000 | 3 | 1.000 | 17 | 68 | 20 | .294 | 75 | 75 | 16 |
| Jo-Jo Reyes* |   | sp | 23 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 23 | 1 | 0 |
| Greg Reynolds |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 1 | 0 |
| Arthur Rhodes* | OTR | mr | 38 | 3 | 2 | .667 | 1 | .333 | 24 | 45 | 8 | .178 | 61 | 61 | 6 |
| Clayton Richard* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 13 | 5 | 3 |
| Scott Richmond |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Jeff Ridgway* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 3 | .375 | 10 | 10 | 2 |
| Juan Rincon |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 3 | 18 | 15 | .833 | 47 | 47 | 15 |
| Ricardo Rincon* |   | mr | 38 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 2 | .222 | 8 | 8 | 1 |
| Royce Ring* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 5 | 34 | 6 | .176 | 42 | 42 | 8 |
| David Riske |   | mr | 31 | 7 | 2 | .286 | 5 | .714 | 11 | 26 | 8 | .308 | 45 | 45 | 6 |
| Mariano Rivera | ROK | cl | 38 | 40 | 39 | .975 | 1 | .025 | 0 | 20 | 4 | .200 | 64 | 64 | 60 |
| Saul Rivera |   | mr | 30 | 7 | 0 | .000 | 7 | 1.000 | 17 | 37 | 15 | .405 | 76 | 76 | 14 |
| Connor Robertson |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 6 | 6 | 3 |
| David Robertson |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 14 | 8 | .571 | 25 | 25 | 8 |
| Nate Robertson* |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 4 | 1 |
| Fernando Rodney | OTR | cl | 31 | 19 | 13 | .684 | 6 | .316 | 5 | 15 | 4 | .267 | 38 | 38 | 25 |
| Francisco Rodriguez | BON | cl | 26 | 69 | 62 | .899 | 7 | .101 | 0 | 18 | 7 | .389 | 76 | 76 | 69 |
| Wandy Rodriguez* | BT | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Josh Roenicke |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 4 | .800 | 5 | 5 | 0 |
| Kenny Rogers* |   | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| J.C. Romero* |   | mr | 32 | 5 | 1 | .200 | 4 | .800 | 24 | 58 | 16 | .276 | 81 | 81 | 14 |
| Sergio Romo |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 5 | 22 | 3 | .136 | 29 | 29 | 8 |
| Carlos Rosa |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 2 | 2 | 1 |
| Leo Rosales |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 15 | 6 | .400 | 27 | 27 | 6 |
| Ryan Rowland-Smith* | CRH | mr | 25 | 3 | 2 | .667 | 1 | .333 | 1 | 30 | 10 | .333 | 47 | 35 | 9 |
| Rich Rundles* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 8 | 8 | 0 |
| Josh Rupe |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 2 | 26 | 10 | .385 | 46 | 46 | 10 |
| Glendon Rusch* |   | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 1 | 21 | 10 | .476 | 35 | 26 | 9 |
| Adam Russell |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 6 | .500 | 22 | 22 | 16 |
| B.J. Ryan* | CRH | cl | 32 | 36 | 32 | .889 | 4 | .111 | 1 | 2 | 0 | .000 | 60 | 60 | 48 |
| Jae Kuk Ryu |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Kirk Saarloos |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 4 | .571 | 8 | 7 | 1 |
| C.C. Sabathia* | CRH | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 |
| Billy Sadler |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 24 | 8 | .333 | 33 | 33 | 8 |
| Takashi Saito | Pal | cl | 38 | 22 | 18 | .818 | 4 | .182 | 0 | 3 | 1 | .333 | 45 | 45 | 35 |
| Juan Salas |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 5 | 5 | 2 |
| Marino Salas |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 1 | .111 | 13 | 13 | 4 |
| Jeff Samardzija |   | mr | 23 | 5 | 1 | .200 | 4 | .800 | 3 | 10 | 6 | .600 | 26 | 26 | 6 |
| Chris Sampson | MUL | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 12 | 27 | 3 | .111 | 54 | 43 | 6 |
| Brian Sanches |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 13 | 9 | .692 | 12 | 12 | 2 |
| Anibal Sanchez | MAD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Duaner Sanchez | BT | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 21 | 20 | 5 | .250 | 66 | 66 | 14 |
| Humberto Sanchez |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 |
| Jonathan Sanchez* | MAD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Romulo Sanchez |   | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 1 | .143 | 10 | 10 | 5 |
| Ervin Santana | BON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Johan Santana* | ROK | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Dennis Sarfate |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 4 | 50 | 19 | .380 | 57 | 53 | 15 |
| Joe Saunders* | MID | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Max Scherzer | LON | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 16 | 9 | 2 |
| Scott Schoeneweis* |   | mr | 34 | 5 | 1 | .200 | 4 | .800 | 15 | 46 | 17 | .370 | 73 | 73 | 12 |
| Chris Schroder |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 0 |
| Rudy Seanez | TON | mr | 39 | 1 | 0 | .000 | 1 | 1.000 | 2 | 14 | 3 | .214 | 42 | 42 | 14 |
| Bobby Seay* |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 13 | 52 | 16 | .308 | 60 | 60 | 14 |
| Alex Serrano |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Ben Sheets | CRH | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Steven Shell | CRH | mr | 25 | 4 | 2 | .500 | 2 | .500 | 7 | 21 | 6 | .286 | 39 | 39 | 7 |
| George Sherrill* | ROK | cl | 31 | 37 | 31 | .838 | 6 | .162 | 0 | 22 | 9 | .409 | 57 | 57 | 49 |
| James Shields | BON | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Scot Shields | ROK | mr | 32 | 9 | 4 | .444 | 5 | .556 | 31 | 15 | 3 | .200 | 64 | 64 | 12 |
| Brian Shouse* | OTR | mr | 39 | 5 | 2 | .400 | 3 | .600 | 15 | 60 | 20 | .333 | 69 | 69 | 17 |
| Carlos Silva |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Alfredo Simon |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 4 | 3 | 0 |
| Doug Slaten* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 4 | 10 | 3 | .300 | 45 | 45 | 13 |
| Brian Slocum |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 2 | 2 | 0 |
| Kevin Slowey |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Chris Smith |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 4 | .444 | 12 | 12 | 3 |
| Greg Smith* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Joe Smith | MAD | mr | 24 | 3 | 0 | .000 | 3 | 1.000 | 18 | 63 | 11 | .175 | 82 | 82 | 12 |
| John Smoltz |   | sp | 41 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 6 | 1 | 0 |
| Ian Snell |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Kyle Snyder |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 |
| Andy Sonnanstine | EDG | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Joakim Soria | BON | cl | 24 | 45 | 42 | .933 | 3 | .067 | 0 | 6 | 2 | .333 | 63 | 63 | 57 |
| Rafael Soriano | GEO | mr | 28 | 4 | 3 | .750 | 1 | .250 | 0 | 0 | 0 | .000 | 14 | 14 | 5 |
| Jorge Sosa |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 15 | 3 | .200 | 20 | 20 | 8 |
| Jeremy Sowers* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Justin Speier |   | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 10 | 32 | 7 | .219 | 62 | 62 | 19 |
| Ryan Speier | MUL | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 3 | 29 | 10 | .345 | 43 | 43 | 8 |
| Levale Speigner |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 7 | 2 |
| Russ Springer | WIZ | mr | 39 | 2 | 0 | .000 | 2 | 1.000 | 16 | 51 | 11 | .216 | 70 | 70 | 9 |
| Mitch Stetter* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 4 | 12 | 1 | .083 | 30 | 30 | 7 |
| Phil Stockman |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 6 | 4 |
| Brian Stokes |   | mr | 28 | 3 | 1 | .333 | 2 | .667 | 4 | 10 | 5 | .500 | 24 | 23 | 5 |
| Huston Street | GEO | cl | 24 | 25 | 18 | .720 | 7 | .280 | 6 | 13 | 2 | .154 | 63 | 63 | 37 |
| Eric Stults* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Tanyon Sturtze |   | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Jeff Suppan |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| R.J. Swindle* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 3 | 3 | 0 |
| Mitch Talbot |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 2 | 0 |
| Brian Tallet* | EDG | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 5 | 24 | 8 | .333 | 51 | 51 | 15 |
| Taylor Tankersley* |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 4 | 20 | 6 | .300 | 25 | 25 | 3 |
| Jack Taschner* |   | mr | 30 | 4 | 0 | .000 | 4 | 1.000 | 14 | 57 | 19 | .333 | 67 | 67 | 7 |
| Ty Taubenheim |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Julian Tavarez |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 6 | 25 | 9 | .360 | 52 | 52 | 15 |
| Robinson Tejeda | OTR | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 22 | 8 | .364 | 29 | 28 | 15 |
| Joe Thatcher* |   | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 5 | 16 | 9 | .563 | 25 | 25 | 7 |
| Justin Thomas* |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 10 | 5 | .500 | 8 | 8 | 2 |
| Brad Thompson |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 1 | 12 | 2 | .167 | 26 | 20 | 10 |
| Daryl Thompson |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Rich Thompson |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Matt Thornton* | CRH | mr | 31 | 6 | 1 | .167 | 5 | .833 | 20 | 56 | 21 | .375 | 74 | 74 | 12 |
| Erick Threets* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 7 | 7 | 6 |
| Mike Timlin |   | mr | 42 | 1 | 1 | 1.000 | 0 | .000 | 0 | 17 | 5 | .294 | 47 | 47 | 26 |
| Brett Tomko |   | sp | 35 | 2 | 0 | .000 | 2 | 1.000 | 0 | 4 | 2 | .500 | 22 | 12 | 3 |
| Salomon Torres | MUL | cl | 36 | 35 | 28 | .800 | 7 | .200 | 5 | 26 | 7 | .269 | 71 | 71 | 46 |
| Billy Traber* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 6 | .600 | 19 | 19 | 3 |
| Steve Trachsel |   | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 2 | 1 |
| Ramon Troncoso |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 19 | 8 | .421 | 32 | 32 | 12 |
| Ryan Tucker |   | mr | 21 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 13 | 7 | 3 |
| Derrick Turnbow |   | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 8 | 5 |
| Merkin Valdez |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 1 | .083 | 17 | 16 | 3 |
| Jose Valverde | WIZ | cl | 28 | 51 | 44 | .863 | 7 | .137 | 0 | 16 | 6 | .375 | 74 | 74 | 71 |
| John Van Benschoten |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 4 | 2 |
| Rick VandenHurk |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Claudio Vargas |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 1 | 2 | 0 | .000 | 11 | 7 | 2 |
| Javier Vazquez | Pal | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jose Veras |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 10 | 13 | 4 | .308 | 60 | 60 | 15 |
| Justin Verlander | COP | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Carlos Villanueva |   | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 12 | 16 | 1 | .063 | 47 | 38 | 9 |
| Oscar Villarreal |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 2 | 11 | 1 | .091 | 35 | 35 | 13 |
| Ron Villone* |   | mr | 38 | 2 | 1 | .500 | 1 | .500 | 16 | 45 | 10 | .222 | 74 | 74 | 11 |
| Luis Vizcaino |   | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 2 | 21 | 6 | .286 | 43 | 43 | 13 |
| Edinson Volquez | LON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 1 | 1 |
| Chris Volstad | MAD | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 1 | 0 |
| Cory Wade | Pal | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 9 | 22 | 5 | .227 | 55 | 55 | 21 |
| Doug Waechter |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 9 | 15 | 5 | .333 | 48 | 48 | 10 |
| Billy Wagner* | BT | cl | 36 | 34 | 27 | .794 | 7 | .206 | 0 | 5 | 3 | .600 | 45 | 45 | 34 |
| Adam Wainwright | MAD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Tim Wakefield | OTR | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Jamie Walker* | OTR | mr | 36 | 4 | 0 | .000 | 4 | 1.000 | 9 | 51 | 16 | .314 | 59 | 59 | 11 |
| Tyler Walker |   | mr | 32 | 4 | 0 | .000 | 4 | 1.000 | 19 | 32 | 7 | .219 | 65 | 65 | 19 |
| Les Walrond* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 6 | 6 | 1 |
| Chien-Ming Wang | MID | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Jarrod Washburn* |   | sp | 33 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 2 | 1 |
| Ehren Wassermann |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 26 | 10 | .385 | 24 | 24 | 6 |
| Chris Waters* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 |
| David Weathers |   | mr | 38 | 4 | 0 | .000 | 4 | 1.000 | 19 | 15 | 2 | .133 | 72 | 72 | 17 |
| Jered Weaver | OTR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Brandon Webb | TON | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Todd Wellemeyer | Pal | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jared Wells |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 3 | .500 | 8 | 8 | 2 |
| Kip Wells |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 2 | .182 | 25 | 23 | 8 |
| Randy Wells |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 2 |
| Jake Westbrook |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Dan Wheeler | Pal | mr | 30 | 18 | 13 | .722 | 5 | .278 | 26 | 25 | 4 | .160 | 70 | 70 | 26 |
| Bill White* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 8 | 8 | 2 |
| Dontrelle Willis* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 1 | 0 |
| Brian Wilson | MUL | cl | 26 | 47 | 41 | .872 | 6 | .128 | 0 | 22 | 3 | .136 | 63 | 63 | 54 |
| C.J. Wilson* | ROK | cl | 27 | 28 | 24 | .857 | 4 | .143 | 1 | 6 | 3 | .500 | 50 | 50 | 41 |
| Matt Wise |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 8 | 8 | 5 |
| Randy Wolf* | CCL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Brian Wolfe |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 3 | 13 | 5 | .385 | 20 | 20 | 4 |
| Kerry Wood | MUL | cl | 31 | 40 | 34 | .850 | 6 | .150 | 0 | 12 | 2 | .167 | 65 | 65 | 56 |
| Jake Woods* |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 11 | 5 | .455 | 15 | 15 | 3 |
| Mark Worrell |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 4 | 4 | 1 |
| Jamey Wright |   | mr | 33 | 7 | 0 | .000 | 7 | 1.000 | 17 | 42 | 18 | .429 | 75 | 75 | 17 |
| Wesley Wright* |   | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 13 | 43 | 9 | .209 | 71 | 71 | 15 |
| Michael Wuertz | ROK | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 3 | 40 | 12 | .300 | 45 | 45 | 13 |
| Keiichi Yabu |   | mr | 39 | 1 | 0 | .000 | 1 | 1.000 | 10 | 41 | 12 | .293 | 60 | 60 | 10 |
| Yasuhiko Yabuta |   | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 0 | 12 | 6 | .500 | 31 | 31 | 12 |
| Tyler Yates |   | mr | 30 | 5 | 1 | .200 | 4 | .800 | 14 | 28 | 4 | .143 | 72 | 72 | 16 |
| Chris Young | COP | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 |
| Carlos Zambrano | CCL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Brad Ziegler | CRH | mr | 28 | 13 | 11 | .846 | 2 | .154 | 9 | 22 | 5 | .227 | 47 | 47 | 21 |
| Charlie Zink |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Barry Zito* |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Joel Zumaya |   | mr | 23 | 5 | 1 | .200 | 4 | .800 | 5 | 11 | 7 | .636 | 21 | 21 | 5 |