Real-life pitching register -- All players in database
Regular season
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | BT | mr | 25 | 6.40 | 2 | 1 | 0 | 25 | 0 | 0 | 0 | 32.1 | 39 | 24 | 23 | 17 | 36 | 4 | 1 |
| Winston Abreu |   | mr | 30 | 5.93 | 0 | 1 | 0 | 26 | 0 | 0 | 0 | 30.1 | 37 | 21 | 20 | 9 | 26 | 7 | 5 |
| Jeremy Accardo | CRH | cl | 25 | 2.14 | 4 | 4 | 30 | 64 | 0 | 0 | 0 | 67.1 | 51 | 19 | 16 | 24 | 57 | 4 | 3 |
| Manny Acosta |   | mr | 26 | 2.28 | 1 | 1 | 0 | 21 | 0 | 0 | 0 | 23.2 | 13 | 6 | 6 | 14 | 22 | 2 | 5 |
| Jon Adkins |   | mr | 29 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Jeremy Affeldt* | CRH | mr | 28 | 3.51 | 4 | 3 | 0 | 75 | 0 | 0 | 0 | 59.0 | 47 | 26 | 23 | 33 | 46 | 3 | 7 |
| Jonathan Albaladejo |   | mr | 24 | 1.88 | 1 | 1 | 0 | 14 | 0 | 0 | 0 | 14.1 | 7 | 3 | 3 | 2 | 12 | 1 | 2 |
| Matt Albers |   | sp | 24 | 5.86 | 4 | 11 | 0 | 31 | 18 | 0 | 0 | 110.2 | 127 | 77 | 72 | 50 | 71 | 18 | 10 |
| Antonio Alfonseca |   | mr | 35 | 5.44 | 5 | 2 | 8 | 61 | 0 | 0 | 0 | 49.2 | 65 | 31 | 30 | 27 | 24 | 3 | 3 |
| Greg Aquino |   | mr | 29 | 4.50 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 14.0 | 13 | 9 | 7 | 5 | 12 | 2 | 1 |
| Alberto Arias |   | mr | 23 | 4.91 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 7.1 | 8 | 4 | 4 | 5 | 3 | 1 | 2 |
| Tony Armas |   | mr | 29 | 6.03 | 4 | 5 | 0 | 31 | 15 | 0 | 0 | 97.0 | 111 | 68 | 65 | 38 | 73 | 18 | 5 |
| Bronson Arroyo | BT | sp | 30 | 4.23 | 9 | 15 | 0 | 34 | 34 | 1 | 0 | 210.2 | 232 | 109 | 99 | 63 | 156 | 28 | 12 |
| Jose Ascanio |   | mr | 22 | 5.06 | 1 | 1 | 0 | 13 | 0 | 0 | 0 | 16.0 | 17 | 11 | 9 | 6 | 13 | 3 | 0 |
| Scott Atchison |   | mr | 31 | 4.11 | 0 | 0 | 0 | 22 | 0 | 0 | 0 | 30.2 | 32 | 14 | 14 | 10 | 25 | 5 | 3 |
| Luis Ayala |   | mr | 29 | 3.19 | 2 | 2 | 1 | 44 | 0 | 0 | 0 | 42.1 | 43 | 16 | 15 | 12 | 28 | 5 | 3 |
| Brandon Backe |   | sp | 29 | 3.77 | 3 | 1 | 0 | 5 | 5 | 0 | 0 | 28.2 | 27 | 13 | 12 | 11 | 11 | 4 | 1 |
| Mike Bacsik* |   | sp | 29 | 5.11 | 5 | 8 | 0 | 29 | 20 | 0 | 0 | 118.0 | 141 | 73 | 67 | 29 | 45 | 26 | 14 |
| Cha Seung Baek | EDG | sp | 27 | 5.15 | 4 | 3 | 0 | 14 | 12 | 1 | 0 | 73.1 | 87 | 45 | 42 | 14 | 49 | 6 | 3 |
| Danys Baez |   | mr | 29 | 6.44 | 0 | 6 | 3 | 53 | 0 | 0 | 0 | 50.1 | 50 | 36 | 36 | 29 | 29 | 8 | 6 |
| Homer Bailey | CCL | sp | 21 | 5.76 | 4 | 2 | 0 | 9 | 9 | 0 | 0 | 45.1 | 43 | 32 | 29 | 28 | 28 | 3 | 6 |
| Scott Baker | BON | sp | 25 | 4.26 | 9 | 9 | 0 | 24 | 23 | 2 | 1 | 143.2 | 162 | 70 | 68 | 29 | 102 | 15 | 17 |
| John Bale* | BON | mr | 33 | 4.05 | 1 | 1 | 0 | 26 | 0 | 0 | 0 | 40.0 | 45 | 18 | 18 | 17 | 42 | 1 | 3 |
| Grant Balfour |   | mr | 29 | 7.66 | 1 | 2 | 0 | 25 | 0 | 0 | 0 | 24.2 | 30 | 21 | 21 | 20 | 30 | 2 | 2 |
| Josh Banks |   | mr | 24 | 7.36 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 7.1 | 11 | 6 | 6 | 2 | 2 | 1 | 0 |
| Brian Bannister | EDG | sp | 26 | 3.87 | 12 | 9 | 0 | 27 | 27 | 1 | 0 | 165.0 | 156 | 76 | 71 | 44 | 77 | 15 | 14 |
| Daniel Barone |   | mr | 24 | 5.71 | 1 | 3 | 0 | 16 | 6 | 0 | 0 | 41.0 | 50 | 29 | 26 | 19 | 18 | 11 | 7 |
| Kevin Barry |   | mr | 28 | 22.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 6 | 5 | 5 | 2 | 4 | 0 | 0 |
| Miguel Batista |   | sp | 36 | 4.29 | 16 | 11 | 0 | 33 | 32 | 0 | 0 | 193.0 | 209 | 101 | 92 | 85 | 133 | 18 | 18 |
| Denny Bautista |   | mr | 26 | 12.46 | 2 | 1 | 0 | 9 | 1 | 0 | 0 | 8.2 | 18 | 12 | 12 | 4 | 8 | 0 | 1 |
| Jonah Bayliss |   | mr | 26 | 8.36 | 4 | 3 | 0 | 39 | 0 | 0 | 0 | 37.2 | 51 | 36 | 35 | 18 | 29 | 8 | 3 |
| Yorman Bazardo |   | mr | 22 | 2.28 | 2 | 1 | 0 | 11 | 2 | 0 | 0 | 23.2 | 19 | 7 | 6 | 5 | 15 | 2 | 4 |
| Colter Bean |   | mr | 30 | 12.00 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 3.0 | 5 | 4 | 4 | 5 | 2 | 0 | 0 |
| Josh Beckett | Pal | sp | 27 | 3.27 | 20 | 7 | 0 | 30 | 30 | 1 | 0 | 200.2 | 189 | 76 | 73 | 40 | 194 | 17 | 12 |
| Erik Bedard* | GEO | sp | 28 | 3.16 | 13 | 5 | 0 | 28 | 28 | 1 | 1 | 182.0 | 141 | 66 | 64 | 57 | 221 | 19 | 13 |
| Joe Beimel* | WIZ | mr | 30 | 3.88 | 4 | 2 | 1 | 83 | 0 | 0 | 0 | 67.1 | 63 | 30 | 29 | 24 | 39 | 1 | 11 |
| Matt Belisle | CCL | sp | 27 | 5.32 | 8 | 9 | 0 | 30 | 30 | 1 | 0 | 177.2 | 212 | 111 | 105 | 43 | 125 | 26 | 15 |
| Heath Bell | MUL | mr | 29 | 2.02 | 6 | 4 | 2 | 81 | 0 | 0 | 0 | 93.2 | 60 | 21 | 21 | 30 | 102 | 3 | 9 |
| Rob Bell |   | mr | 30 | 5.94 | 4 | 3 | 0 | 30 | 0 | 0 | 0 | 53.0 | 73 | 37 | 35 | 24 | 28 | 7 | 4 |
| Armando Benitez |   | mr | 34 | 5.36 | 2 | 8 | 9 | 55 | 0 | 0 | 0 | 50.1 | 49 | 37 | 30 | 29 | 57 | 8 | 4 |
| Jeff Bennett |   | sp | 27 | 3.46 | 2 | 1 | 0 | 3 | 2 | 0 | 0 | 13.0 | 14 | 5 | 5 | 3 | 14 | 3 | 0 |
| Joaquin Benoit | OTR | mr | 29 | 2.85 | 7 | 4 | 6 | 70 | 0 | 0 | 0 | 82.0 | 68 | 28 | 26 | 28 | 87 | 6 | 5 |
| Jason Bergmann |   | sp | 25 | 4.45 | 6 | 6 | 0 | 21 | 21 | 0 | 0 | 115.1 | 99 | 59 | 57 | 42 | 86 | 18 | 7 |
| Rafael Betancourt | GEO | mr | 32 | 1.47 | 5 | 1 | 3 | 68 | 0 | 0 | 0 | 79.1 | 51 | 13 | 13 | 9 | 80 | 4 | 3 |
| Chad Billingsley | TON | mr | 22 | 3.31 | 12 | 5 | 0 | 43 | 20 | 1 | 0 | 147.0 | 131 | 56 | 54 | 64 | 141 | 15 | 14 |
| Kurt Birkins* |   | mr | 26 | 8.13 | 1 | 2 | 0 | 19 | 2 | 0 | 0 | 34.1 | 52 | 31 | 31 | 14 | 30 | 3 | 2 |
| Joe Bisenius |   | mr | 24 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 0 | 0 | 2 | 3 | 0 | 0 |
| Nick Blackburn |   | mr | 25 | 7.71 | 0 | 2 | 0 | 6 | 0 | 0 | 0 | 11.2 | 19 | 12 | 10 | 2 | 8 | 2 | 2 |
| Travis Blackley* |   | sp | 24 | 7.27 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 8.2 | 10 | 7 | 7 | 5 | 5 | 2 | 1 |
| Joe Blanton | BON | sp | 26 | 3.95 | 14 | 10 | 0 | 34 | 34 | 3 | 1 | 230.0 | 240 | 106 | 101 | 40 | 140 | 16 | 22 |
| Jerry Blevins* |   | mr | 23 | 9.64 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 4.2 | 8 | 6 | 5 | 2 | 3 | 1 | 0 |
| Jeremy Bonderman |   | sp | 24 | 5.01 | 11 | 9 | 0 | 28 | 28 | 0 | 0 | 174.1 | 193 | 105 | 97 | 48 | 145 | 23 | 16 |
| Boof Bonser |   | sp | 25 | 5.10 | 8 | 12 | 0 | 31 | 30 | 0 | 0 | 173.0 | 199 | 108 | 98 | 65 | 136 | 27 | 12 |
| Chris Booker |   | mr | 30 | 18.00 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 1.0 | 1 | 2 | 2 | 1 | 1 | 1 | 0 |
| Chris Bootcheck |   | mr | 28 | 4.77 | 3 | 3 | 0 | 51 | 0 | 0 | 0 | 77.1 | 81 | 43 | 41 | 24 | 56 | 7 | 9 |
| Dave Borkowski |   | mr | 30 | 5.15 | 5 | 3 | 1 | 64 | 0 | 0 | 0 | 71.2 | 76 | 46 | 41 | 34 | 63 | 8 | 4 |
| Joe Borowski | EDG | cl | 36 | 5.07 | 4 | 5 | 45 | 69 | 0 | 0 | 0 | 65.2 | 77 | 39 | 37 | 17 | 58 | 9 | 1 |
| Micah Bowie* |   | mr | 32 | 4.55 | 4 | 3 | 0 | 30 | 8 | 0 | 0 | 57.1 | 55 | 30 | 29 | 27 | 42 | 7 | 8 |
| Blaine Boyer |   | mr | 25 | 3.38 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 5.1 | 10 | 3 | 2 | 1 | 3 | 0 | 0 |
| Dallas Braden* |   | sp | 23 | 6.72 | 1 | 8 | 0 | 20 | 14 | 0 | 0 | 72.1 | 91 | 59 | 54 | 26 | 55 | 9 | 4 |
| Chad Bradford | MID | mr | 32 | 3.34 | 4 | 7 | 2 | 78 | 0 | 0 | 0 | 64.2 | 77 | 28 | 24 | 16 | 29 | 1 | 7 |
| Ryan Braun |   | mr | 26 | 6.64 | 2 | 0 | 0 | 26 | 0 | 0 | 0 | 39.1 | 46 | 32 | 29 | 22 | 24 | 4 | 4 |
| Bill Bray* |   | mr | 24 | 6.28 | 3 | 3 | 1 | 19 | 0 | 0 | 0 | 14.1 | 16 | 10 | 10 | 5 | 14 | 1 | 1 |
| Yhency Brazoban |   | mr | 27 | 16.20 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1.2 | 3 | 4 | 3 | 3 | 5 | 0 | 0 |
| Chris Britton |   | mr | 24 | 3.55 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | 12.2 | 9 | 5 | 5 | 4 | 5 | 2 | 0 |
| Lance Broadway |   | mr | 23 | 0.87 | 1 | 1 | 0 | 4 | 1 | 0 | 0 | 10.1 | 5 | 2 | 1 | 5 | 14 | 0 | 1 |
| Doug Brocail | CCL | mr | 40 | 3.05 | 5 | 1 | 0 | 67 | 0 | 0 | 0 | 76.2 | 66 | 33 | 26 | 24 | 43 | 8 | 5 |
| Jim Brower |   | mr | 34 | 13.50 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.1 | 8 | 7 | 5 | 2 | 1 | 0 | 1 |
| Andrew Brown | EDG | mr | 26 | 4.54 | 3 | 3 | 0 | 33 | 0 | 0 | 0 | 41.2 | 38 | 21 | 21 | 17 | 43 | 1 | 2 |
| Jonathan Broxton | CCL | mr | 23 | 2.85 | 4 | 4 | 2 | 83 | 0 | 0 | 0 | 82.0 | 69 | 30 | 26 | 25 | 99 | 6 | 7 |
| Brian Bruney |   | mr | 25 | 4.68 | 3 | 2 | 0 | 58 | 0 | 0 | 0 | 50.0 | 44 | 28 | 26 | 37 | 39 | 5 | 5 |
| Clay Buchholz |   | sp | 22 | 1.59 | 3 | 1 | 0 | 4 | 3 | 1 | 1 | 22.2 | 14 | 6 | 4 | 10 | 22 | 0 | 3 |
| Taylor Buchholz | TON | mr | 25 | 4.23 | 6 | 5 | 0 | 41 | 8 | 0 | 0 | 93.2 | 105 | 47 | 44 | 20 | 61 | 8 | 11 |
| Billy Buckner |   | sp | 23 | 5.29 | 1 | 2 | 0 | 7 | 5 | 0 | 0 | 34.0 | 37 | 20 | 20 | 16 | 17 | 5 | 9 |
| Mark Buehrle* | GEO | sp | 28 | 3.63 | 10 | 9 | 0 | 30 | 30 | 3 | 1 | 201.0 | 208 | 86 | 81 | 45 | 115 | 22 | 20 |
| Ryan Bukvich |   | mr | 29 | 5.05 | 1 | 0 | 0 | 45 | 0 | 0 | 0 | 35.2 | 36 | 23 | 20 | 24 | 18 | 5 | 4 |
| Jason Bulger |   | mr | 28 | 2.84 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 6.1 | 5 | 2 | 2 | 3 | 8 | 0 | 1 |
| Bryan Bullington |   | sp | 26 | 5.29 | 0 | 3 | 0 | 5 | 3 | 0 | 0 | 17.0 | 24 | 11 | 10 | 5 | 7 | 3 | 3 |
| Ambiorix Burgos |   | mr | 23 | 3.42 | 1 | 0 | 0 | 17 | 0 | 0 | 0 | 23.2 | 17 | 10 | 9 | 9 | 19 | 3 | 1 |
| A.J. Burnett | TON | sp | 30 | 3.75 | 10 | 8 | 0 | 25 | 25 | 2 | 0 | 165.2 | 131 | 74 | 69 | 66 | 176 | 23 | 19 |
| Brian Burres* |   | mr | 26 | 5.95 | 6 | 8 | 0 | 37 | 17 | 0 | 0 | 121.0 | 140 | 81 | 80 | 66 | 96 | 14 | 9 |
| Jared Burton | MAD | mr | 26 | 2.51 | 4 | 2 | 0 | 47 | 0 | 0 | 0 | 43.0 | 28 | 15 | 12 | 22 | 36 | 2 | 5 |
| Dave Bush | OTR | sp | 27 | 5.12 | 12 | 10 | 0 | 33 | 31 | 0 | 0 | 186.1 | 217 | 110 | 106 | 44 | 134 | 27 | 13 |
| Paul Byrd |   | sp | 36 | 4.59 | 15 | 8 | 0 | 31 | 31 | 2 | 2 | 192.1 | 239 | 107 | 98 | 28 | 88 | 27 | 14 |
| Tim Byrdak* | EDG | mr | 33 | 3.20 | 3 | 0 | 1 | 39 | 0 | 0 | 0 | 45.0 | 38 | 23 | 16 | 26 | 49 | 3 | 4 |
| Daniel Cabrera |   | sp | 26 | 5.55 | 9 | 18 | 0 | 34 | 34 | 1 | 0 | 204.1 | 207 | 133 | 126 | 108 | 166 | 25 | 21 |
| Fernando Cabrera |   | mr | 25 | 7.21 | 1 | 2 | 1 | 33 | 0 | 0 | 0 | 43.2 | 50 | 36 | 35 | 31 | 48 | 9 | 1 |
| Matt Cain | LON | sp | 22 | 3.64 | 7 | 16 | 0 | 32 | 32 | 1 | 0 | 200.0 | 173 | 84 | 81 | 79 | 163 | 14 | 16 |
| Kiko Calero |   | mr | 32 | 5.75 | 1 | 5 | 1 | 46 | 0 | 0 | 0 | 40.2 | 46 | 26 | 26 | 21 | 31 | 3 | 3 |
| Carmen Cali* |   | mr | 28 | 4.71 | 0 | 1 | 0 | 24 | 0 | 0 | 0 | 21.0 | 22 | 11 | 11 | 16 | 14 | 2 | 1 |
| Kevin Cameron | LON | mr | 27 | 2.79 | 2 | 0 | 0 | 48 | 0 | 0 | 0 | 58.0 | 55 | 24 | 18 | 36 | 50 | 0 | 5 |
| Shawn Camp |   | mr | 31 | 7.20 | 0 | 3 | 0 | 50 | 0 | 0 | 0 | 40.0 | 63 | 33 | 32 | 18 | 36 | 7 | 9 |
| Jorge Campillo |   | mr | 28 | 6.75 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 13.1 | 18 | 12 | 10 | 6 | 9 | 2 | 2 |
| Jose Capellan |   | mr | 26 | 5.54 | 0 | 3 | 0 | 17 | 0 | 0 | 0 | 26.0 | 28 | 19 | 16 | 9 | 20 | 7 | 0 |
| Matt Capps | MUL | mr | 23 | 2.28 | 4 | 7 | 18 | 76 | 0 | 0 | 0 | 79.0 | 64 | 22 | 20 | 16 | 64 | 5 | 4 |
| Chris Capuano* |   | sp | 28 | 5.10 | 5 | 12 | 0 | 29 | 25 | 0 | 0 | 150.0 | 170 | 93 | 85 | 54 | 132 | 20 | 14 |
| Buddy Carlyle |   | sp | 29 | 5.21 | 8 | 7 | 0 | 22 | 20 | 0 | 0 | 107.0 | 117 | 67 | 62 | 32 | 74 | 19 | 11 |
| Fausto Carmona | GEO | sp | 23 | 3.06 | 19 | 8 | 0 | 32 | 32 | 2 | 1 | 215.0 | 199 | 78 | 73 | 61 | 137 | 16 | 32 |
| Chris Carpenter | CRH | sp | 32 | 7.50 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 6.0 | 9 | 5 | 5 | 1 | 3 | 0 | 0 |
| Hector Carrasco |   | mr | 37 | 6.57 | 2 | 1 | 0 | 29 | 1 | 0 | 0 | 38.1 | 44 | 34 | 28 | 23 | 33 | 8 | 2 |
| Marcos Carvajal |   | mr | 22 | 6.75 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.0 | 8 | 4 | 3 | 2 | 2 | 0 | 0 |
| Santiago Casilla | OTR | mr | 26 | 4.44 | 3 | 1 | 2 | 46 | 0 | 0 | 0 | 50.2 | 43 | 25 | 25 | 23 | 52 | 6 | 1 |
| Jack Cassel |   | sp | 26 | 3.97 | 1 | 1 | 0 | 6 | 4 | 0 | 0 | 22.2 | 30 | 10 | 10 | 5 | 11 | 1 | 4 |
| Fabio Castro* |   | mr | 22 | 6.00 | 0 | 0 | 0 | 10 | 1 | 0 | 0 | 12.0 | 9 | 8 | 8 | 13 | 14 | 2 | 2 |
| Troy Cate* |   | mr | 26 | 3.38 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 16.0 | 18 | 7 | 6 | 9 | 12 | 1 | 1 |
| Andy Cavazos |   | mr | 26 | 10.35 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 20.0 | 27 | 27 | 23 | 16 | 15 | 5 | 2 |
| Gustavo Chacin* |   | sp | 26 | 5.60 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 27.1 | 29 | 17 | 17 | 7 | 11 | 6 | 2 |
| Shawn Chacon |   | mr | 29 | 3.94 | 5 | 4 | 1 | 64 | 4 | 0 | 0 | 96.0 | 95 | 42 | 42 | 48 | 79 | 9 | 8 |
| Joba Chamberlain |   | mr | 21 | 0.38 | 2 | 0 | 1 | 19 | 0 | 0 | 0 | 24.0 | 12 | 2 | 1 | 6 | 34 | 1 | 1 |
| Bruce Chen* |   | mr | 30 | 7.20 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 10.0 | 11 | 11 | 8 | 6 | 7 | 3 | 2 |
| Rocky Cherry |   | mr | 27 | 5.46 | 1 | 1 | 0 | 22 | 0 | 0 | 0 | 31.1 | 30 | 20 | 19 | 19 | 23 | 4 | 2 |
| Matt Chico* |   | sp | 24 | 4.63 | 7 | 9 | 0 | 31 | 31 | 0 | 0 | 167.0 | 183 | 96 | 86 | 74 | 94 | 26 | 12 |
| Randy Choate* |   | mr | 31 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| Vinnie Chulk |   | mr | 28 | 3.57 | 5 | 4 | 0 | 57 | 0 | 0 | 0 | 53.0 | 53 | 22 | 21 | 14 | 41 | 3 | 4 |
| Darren Clarke |   | mr | 26 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 2 | 0 | 0 | 1 | 1 | 0 | 0 |
| Roger Clemens | ROK | sp | 44 | 4.18 | 6 | 6 | 0 | 18 | 17 | 0 | 0 | 99.0 | 99 | 52 | 46 | 31 | 68 | 9 | 9 |
| Tyler Clippard |   | sp | 22 | 6.33 | 3 | 1 | 0 | 6 | 6 | 0 | 0 | 27.0 | 29 | 19 | 19 | 17 | 18 | 6 | 2 |
| Todd Coffey |   | mr | 26 | 5.82 | 2 | 1 | 0 | 58 | 0 | 0 | 0 | 51.0 | 70 | 36 | 33 | 19 | 43 | 12 | 10 |
| Willie Collazo* |   | mr | 27 | 6.35 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 5.2 | 7 | 4 | 4 | 5 | 0 | 0 | 2 |
| Jesus Colome |   | mr | 29 | 3.82 | 5 | 1 | 1 | 61 | 0 | 0 | 0 | 66.0 | 64 | 30 | 28 | 27 | 43 | 6 | 5 |
| Bartolo Colon |   | sp | 34 | 6.34 | 6 | 8 | 0 | 19 | 18 | 0 | 0 | 99.1 | 132 | 74 | 70 | 29 | 76 | 15 | 10 |
| Steve Colyer* |   | mr | 28 | 4.91 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 3.2 | 9 | 2 | 2 | 4 | 4 | 1 | 0 |
| Clay Condrey |   | mr | 31 | 5.04 | 5 | 0 | 2 | 39 | 0 | 0 | 0 | 50.0 | 61 | 30 | 28 | 16 | 27 | 4 | 5 |
| Jose Contreras |   | sp | 35 | 5.57 | 10 | 17 | 0 | 32 | 30 | 2 | 2 | 189.0 | 232 | 134 | 117 | 62 | 113 | 21 | 19 |
| Aaron Cook | MAD | sp | 28 | 4.12 | 8 | 7 | 0 | 25 | 25 | 2 | 0 | 166.0 | 178 | 87 | 76 | 44 | 61 | 15 | 27 |
| Tim Corcoran |   | mr | 29 | 6.75 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 17.1 | 17 | 14 | 13 | 12 | 6 | 2 | 3 |
| Chad Cordero |   | cl | 25 | 3.36 | 3 | 3 | 37 | 76 | 0 | 0 | 0 | 75.0 | 75 | 31 | 28 | 29 | 62 | 8 | 7 |
| Francisco Cordero | CRH | cl | 32 | 2.98 | 0 | 4 | 44 | 66 | 0 | 0 | 0 | 63.1 | 52 | 23 | 21 | 18 | 86 | 4 | 2 |
| Bryan Corey |   | mr | 33 | 1.93 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 9.1 | 6 | 2 | 2 | 4 | 6 | 0 | 4 |
| Lance Cormier |   | sp | 26 | 7.09 | 2 | 6 | 0 | 10 | 9 | 0 | 0 | 45.2 | 56 | 38 | 36 | 22 | 27 | 16 | 6 |
| Rheal Cormier* |   | mr | 40 | 9.00 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 3.0 | 4 | 3 | 3 | 1 | 1 | 1 | 1 |
| Manny Corpas | MUL | mr | 24 | 2.08 | 4 | 2 | 19 | 78 | 0 | 0 | 0 | 78.0 | 63 | 20 | 18 | 20 | 58 | 6 | 11 |
| Kevin Correia | MUL | mr | 26 | 3.45 | 4 | 7 | 0 | 59 | 8 | 0 | 0 | 101.2 | 94 | 39 | 39 | 40 | 80 | 9 | 4 |
| Neal Cotts* |   | mr | 27 | 4.86 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 16.2 | 15 | 9 | 9 | 9 | 14 | 1 | 4 |
| Jon Coutlangus* |   | mr | 26 | 4.39 | 4 | 2 | 0 | 64 | 0 | 0 | 0 | 41.0 | 38 | 22 | 20 | 27 | 38 | 3 | 6 |
| Jesse Crain |   | mr | 25 | 5.51 | 1 | 2 | 0 | 18 | 0 | 0 | 0 | 16.1 | 19 | 16 | 10 | 4 | 10 | 4 | 2 |
| Juan Cruz | TON | mr | 28 | 3.10 | 6 | 1 | 0 | 53 | 0 | 0 | 0 | 61.0 | 45 | 28 | 21 | 32 | 87 | 7 | 2 |
| John Danks* | EDG | sp | 22 | 5.50 | 6 | 13 | 0 | 26 | 26 | 0 | 0 | 139.0 | 160 | 92 | 85 | 54 | 109 | 28 | 12 |
| Dave Davidson* |   | mr | 23 | 22.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 6 | 6 | 5 | 2 | 0 | 1 | 0 |
| Kyle Davies |   | sp | 23 | 6.09 | 7 | 15 | 0 | 28 | 28 | 0 | 0 | 136.0 | 155 | 102 | 92 | 70 | 99 | 22 | 9 |
| Doug Davis* |   | sp | 31 | 4.25 | 13 | 12 | 0 | 33 | 33 | 0 | 0 | 192.2 | 211 | 100 | 91 | 95 | 144 | 21 | 23 |
| Jason Davis |   | mr | 27 | 5.84 | 2 | 0 | 0 | 24 | 0 | 0 | 0 | 37.0 | 42 | 27 | 24 | 25 | 19 | 4 | 7 |
| Kane Davis |   | mr | 32 | 5.56 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | 11.1 | 17 | 7 | 7 | 8 | 10 | 2 | 1 |
| Dewon Day |   | mr | 26 | 11.25 | 0 | 1 | 0 | 13 | 0 | 0 | 0 | 12.0 | 19 | 15 | 15 | 9 | 7 | 1 | 2 |
| Jordan De Jong |   | mr | 28 | 8.00 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 9.0 | 11 | 9 | 8 | 5 | 7 | 0 | 2 |
| Eulogio De La Cruz |   | mr | 23 | 6.75 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 6.2 | 10 | 8 | 5 | 4 | 5 | 1 | 2 |
| Jorge De La Rosa* |   | sp | 26 | 5.82 | 8 | 12 | 0 | 26 | 23 | 0 | 0 | 130.0 | 160 | 88 | 84 | 53 | 82 | 20 | 13 |
| Manny Delcarmen | GEO | mr | 25 | 2.05 | 0 | 0 | 1 | 44 | 0 | 0 | 0 | 44.0 | 28 | 11 | 10 | 17 | 41 | 4 | 1 |
| Ryan Dempster | CRH | cl | 30 | 4.72 | 2 | 7 | 28 | 66 | 0 | 0 | 0 | 66.2 | 59 | 36 | 35 | 30 | 55 | 8 | 6 |
| Julio DePaula |   | mr | 24 | 8.55 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 20.0 | 30 | 20 | 19 | 10 | 8 | 5 | 4 |
| Matt DeSalvo |   | sp | 26 | 6.18 | 1 | 3 | 0 | 7 | 6 | 0 | 0 | 27.2 | 34 | 20 | 19 | 18 | 10 | 2 | 4 |
| Elmer Dessens |   | mr | 36 | 7.15 | 2 | 2 | 0 | 17 | 5 | 0 | 0 | 34.0 | 45 | 32 | 27 | 12 | 22 | 6 | 3 |
| Ross Detwiler* |   | mr | 21 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Joey Devine |   | mr | 23 | 1.08 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 8.1 | 7 | 1 | 1 | 8 | 7 | 0 | 1 |
| Lenny DiNardo* |   | sp | 27 | 4.11 | 8 | 10 | 0 | 35 | 20 | 0 | 0 | 131.1 | 136 | 74 | 60 | 50 | 59 | 13 | 27 |
| Scott Dohmann |   | mr | 29 | 3.31 | 3 | 0 | 0 | 31 | 0 | 0 | 0 | 32.2 | 29 | 13 | 12 | 18 | 26 | 3 | 4 |
| Brendan Donnelly |   | mr | 35 | 3.05 | 2 | 1 | 0 | 27 | 0 | 0 | 0 | 20.2 | 19 | 8 | 7 | 5 | 15 | 0 | 0 |
| Octavio Dotel |   | cl | 33 | 4.11 | 2 | 1 | 11 | 33 | 0 | 0 | 0 | 30.2 | 29 | 16 | 14 | 12 | 41 | 4 | 1 |
| Dennis Dove |   | mr | 25 | 15.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.0 | 5 | 5 | 5 | 1 | 1 | 2 | 0 |
| Scott Downs* | EDG | mr | 31 | 2.17 | 4 | 2 | 1 | 81 | 0 | 0 | 0 | 58.0 | 47 | 15 | 14 | 24 | 57 | 3 | 6 |
| Cory Doyne |   | mr | 25 | 14.73 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3.2 | 7 | 6 | 6 | 3 | 2 | 1 | 0 |
| Travis Driskill |   | mr | 35 | 4.50 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 6.0 | 10 | 6 | 3 | 1 | 4 | 1 | 1 |
| Justin Duchscherer | COP | mr | 29 | 4.96 | 3 | 3 | 0 | 17 | 0 | 0 | 0 | 16.1 | 18 | 9 | 9 | 8 | 13 | 3 | 0 |
| Brandon Duckworth |   | mr | 31 | 4.63 | 3 | 5 | 1 | 26 | 3 | 0 | 0 | 46.2 | 51 | 30 | 24 | 23 | 21 | 3 | 5 |
| Zach Duke* |   | sp | 24 | 5.53 | 3 | 8 | 0 | 20 | 19 | 0 | 0 | 107.1 | 161 | 74 | 66 | 25 | 41 | 14 | 23 |
| Phil Dumatrait* |   | sp | 25 | 15.00 | 0 | 4 | 0 | 6 | 6 | 0 | 0 | 18.0 | 39 | 30 | 30 | 12 | 9 | 6 | 1 |
| Chad Durbin |   | sp | 29 | 4.72 | 8 | 7 | 1 | 36 | 19 | 0 | 0 | 127.2 | 133 | 71 | 67 | 49 | 66 | 21 | 10 |
| J.D. Durbin |   | sp | 25 | 6.06 | 6 | 5 | 1 | 19 | 10 | 1 | 1 | 65.1 | 78 | 49 | 44 | 37 | 40 | 6 | 7 |
| Adam Eaton |   | sp | 29 | 6.29 | 10 | 10 | 0 | 30 | 30 | 0 | 0 | 161.2 | 192 | 117 | 113 | 71 | 97 | 30 | 14 |
| Scott Elarton |   | sp | 31 | 10.46 | 2 | 4 | 0 | 9 | 9 | 0 | 0 | 37.0 | 53 | 44 | 43 | 21 | 13 | 12 | 6 |
| Alan Embree* | BON | cl | 37 | 3.97 | 1 | 2 | 17 | 68 | 0 | 0 | 0 | 68.0 | 67 | 30 | 30 | 19 | 51 | 5 | 4 |
| John Ennis |   | cl | 27 | 8.22 | 0 | 0 | 1 | 3 | 1 | 0 | 0 | 7.2 | 12 | 7 | 7 | 3 | 8 | 1 | 0 |
| Kelvim Escobar | BON | sp | 31 | 3.40 | 18 | 7 | 0 | 30 | 30 | 3 | 1 | 195.2 | 182 | 79 | 74 | 66 | 160 | 11 | 28 |
| Dana Eveland* |   | mr | 23 | 14.40 | 1 | 0 | 0 | 5 | 1 | 0 | 0 | 5.0 | 8 | 8 | 8 | 5 | 3 | 0 | 0 |
| Scott Eyre* |   | mr | 35 | 4.13 | 2 | 1 | 0 | 55 | 0 | 0 | 0 | 52.1 | 59 | 26 | 24 | 35 | 45 | 3 | 9 |
| Willie Eyre |   | mr | 28 | 5.16 | 4 | 6 | 1 | 33 | 2 | 0 | 0 | 68.0 | 78 | 42 | 39 | 32 | 42 | 8 | 5 |
| Brian Falkenborg |   | mr | 29 | 4.82 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 18.2 | 22 | 10 | 10 | 8 | 16 | 2 | 3 |
| Kyle Farnsworth |   | mr | 31 | 4.80 | 2 | 1 | 0 | 64 | 0 | 0 | 0 | 60.0 | 60 | 35 | 32 | 27 | 48 | 9 | 1 |
| Ryan Feierabend* |   | sp | 21 | 8.03 | 1 | 6 | 0 | 13 | 9 | 0 | 0 | 49.1 | 73 | 44 | 44 | 23 | 27 | 10 | 3 |
| Scott Feldman | MID | mr | 24 | 5.77 | 1 | 2 | 0 | 29 | 0 | 0 | 0 | 39.0 | 44 | 26 | 25 | 32 | 19 | 3 | 4 |
| Pedro Feliciano* | MAD | mr | 30 | 3.09 | 2 | 2 | 2 | 78 | 0 | 0 | 0 | 64.0 | 47 | 26 | 22 | 31 | 61 | 3 | 8 |
| Nate Field |   | mr | 31 | 27.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 3 | 3 | 3 | 1 | 2 | 0 | 0 |
| Randy Flores* |   | mr | 31 | 4.25 | 3 | 0 | 1 | 70 | 0 | 0 | 0 | 55.0 | 71 | 31 | 26 | 15 | 47 | 2 | 5 |
| Ron Flores* |   | mr | 27 | 3.57 | 0 | 2 | 0 | 17 | 0 | 0 | 0 | 17.2 | 16 | 8 | 7 | 12 | 15 | 2 | 0 |
| Gavin Floyd | TON | sp | 24 | 5.27 | 1 | 5 | 0 | 16 | 10 | 0 | 0 | 70.0 | 85 | 45 | 41 | 19 | 49 | 17 | 9 |
| Josh Fogg |   | sp | 30 | 4.94 | 10 | 9 | 0 | 30 | 29 | 0 | 0 | 165.2 | 194 | 99 | 91 | 59 | 94 | 23 | 13 |
| Casey Fossum* |   | mr | 29 | 7.70 | 5 | 8 | 0 | 40 | 10 | 0 | 0 | 76.0 | 109 | 71 | 65 | 27 | 53 | 15 | 8 |
| Jeff Francis* | MAD | sp | 26 | 4.22 | 17 | 9 | 0 | 34 | 34 | 1 | 1 | 215.1 | 234 | 103 | 101 | 63 | 165 | 25 | 22 |
| Frank Francisco | EDG | mr | 27 | 4.55 | 1 | 1 | 0 | 59 | 0 | 0 | 0 | 59.1 | 57 | 33 | 30 | 38 | 49 | 3 | 3 |
| Ryan Franklin | LON | mr | 34 | 3.04 | 4 | 4 | 1 | 69 | 0 | 0 | 0 | 80.0 | 70 | 28 | 27 | 11 | 44 | 8 | 6 |
| Jason Frasor | MID | mr | 29 | 4.58 | 1 | 5 | 3 | 51 | 0 | 0 | 0 | 57.0 | 47 | 29 | 29 | 23 | 59 | 3 | 1 |
| Brian Fuentes* | CCL | cl | 31 | 3.08 | 3 | 5 | 20 | 64 | 0 | 0 | 0 | 61.1 | 46 | 26 | 21 | 23 | 56 | 6 | 3 |
| Aaron Fultz* | MAD | mr | 33 | 2.92 | 4 | 3 | 0 | 49 | 0 | 0 | 0 | 37.0 | 31 | 12 | 12 | 18 | 28 | 2 | 1 |
| Kason Gabbard* | CRH | sp | 25 | 4.65 | 6 | 1 | 0 | 15 | 15 | 1 | 1 | 81.1 | 68 | 42 | 42 | 41 | 55 | 8 | 13 |
| Eric Gagne | GEO | cl | 31 | 3.81 | 4 | 2 | 16 | 54 | 0 | 0 | 0 | 52.0 | 49 | 22 | 22 | 21 | 51 | 3 | 3 |
| Armando Galarraga |   | mr | 25 | 6.23 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 8.2 | 8 | 6 | 6 | 7 | 6 | 2 | 0 |
| Sean Gallagher |   | mr | 21 | 8.59 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 14.2 | 19 | 15 | 14 | 12 | 5 | 3 | 3 |
| Yovani Gallardo | LON | sp | 21 | 3.67 | 9 | 5 | 0 | 20 | 17 | 0 | 0 | 110.1 | 103 | 48 | 45 | 37 | 101 | 8 | 11 |
| Anderson Garcia |   | mr | 26 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| Freddy Garcia |   | sp | 31 | 5.90 | 1 | 5 | 0 | 11 | 11 | 0 | 0 | 58.0 | 74 | 39 | 38 | 19 | 50 | 12 | 5 |
| Harvey Garcia |   | mr | 23 | 4.38 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 12.1 | 14 | 6 | 6 | 7 | 15 | 3 | 1 |
| Lee Gardner | MAD | mr | 32 | 1.94 | 3 | 4 | 2 | 62 | 0 | 0 | 0 | 74.1 | 72 | 19 | 16 | 18 | 52 | 2 | 6 |
| Jon Garland | COP | sp | 27 | 4.23 | 10 | 13 | 0 | 32 | 32 | 2 | 1 | 208.1 | 219 | 114 | 98 | 57 | 98 | 19 | 20 |
| Matt Garza | GEO | sp | 23 | 3.69 | 5 | 7 | 0 | 16 | 15 | 0 | 0 | 83.0 | 96 | 44 | 34 | 32 | 67 | 8 | 11 |
| Chad Gaudin |   | sp | 24 | 4.42 | 11 | 13 | 0 | 34 | 34 | 1 | 0 | 199.1 | 205 | 108 | 98 | 100 | 154 | 21 | 26 |
| Geoff Geary |   | mr | 30 | 4.41 | 3 | 2 | 0 | 57 | 0 | 0 | 0 | 67.1 | 72 | 44 | 33 | 25 | 38 | 8 | 13 |
| Justin Germano | CCL | sp | 24 | 4.45 | 7 | 10 | 0 | 26 | 23 | 0 | 0 | 133.1 | 133 | 72 | 66 | 40 | 78 | 14 | 17 |
| Dan Giese |   | mr | 30 | 4.82 | 0 | 2 | 0 | 8 | 0 | 0 | 0 | 9.1 | 8 | 5 | 5 | 2 | 7 | 4 | 0 |
| Tom Glavine* | WIZ | sp | 41 | 4.45 | 13 | 8 | 0 | 34 | 34 | 1 | 1 | 200.1 | 219 | 102 | 99 | 64 | 89 | 23 | 21 |
| Gary Glover |   | mr | 30 | 4.89 | 6 | 5 | 2 | 67 | 0 | 0 | 0 | 77.1 | 87 | 44 | 42 | 27 | 51 | 12 | 9 |
| Jimmy Gobble* |   | mr | 25 | 3.02 | 4 | 1 | 1 | 74 | 0 | 0 | 0 | 53.2 | 56 | 23 | 18 | 23 | 50 | 6 | 6 |
| Edgar Gonzalez |   | mr | 24 | 5.03 | 8 | 4 | 0 | 32 | 12 | 0 | 0 | 102.0 | 110 | 61 | 57 | 28 | 62 | 18 | 12 |
| Enrique Gonzalez |   | mr | 24 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 4 | 4 | 3 | 1 | 0 | 0 | 1 |
| Mike Gonzalez* |   | mr | 29 | 1.59 | 2 | 0 | 2 | 18 | 0 | 0 | 0 | 17.0 | 15 | 3 | 3 | 8 | 13 | 0 | 2 |
| Tom Gordon |   | mr | 39 | 4.72 | 3 | 2 | 6 | 44 | 0 | 0 | 0 | 40.0 | 40 | 21 | 21 | 13 | 32 | 7 | 6 |
| Tom Gorzelanny* | LON | sp | 24 | 3.88 | 14 | 10 | 0 | 32 | 32 | 1 | 1 | 201.2 | 214 | 90 | 87 | 68 | 135 | 18 | 17 |
| Mike Gosling* |   | mr | 26 | 4.91 | 2 | 0 | 0 | 23 | 0 | 0 | 0 | 33.0 | 42 | 22 | 18 | 28 | 32 | 5 | 5 |
| John Grabow* |   | mr | 28 | 4.53 | 3 | 2 | 1 | 63 | 0 | 0 | 0 | 51.2 | 56 | 27 | 26 | 19 | 42 | 6 | 5 |
| Sean Green |   | mr | 28 | 3.84 | 5 | 2 | 0 | 64 | 0 | 0 | 0 | 68.0 | 77 | 31 | 29 | 34 | 53 | 2 | 11 |
| Kevin Gregg | BT | cl | 29 | 3.54 | 0 | 5 | 32 | 74 | 0 | 0 | 0 | 84.0 | 63 | 34 | 33 | 40 | 87 | 7 | 4 |
| Zack Greinke | COP | mr | 23 | 3.69 | 7 | 7 | 1 | 52 | 14 | 0 | 0 | 122.0 | 122 | 52 | 50 | 36 | 106 | 12 | 11 |
| Jason Grilli | COP | mr | 30 | 4.74 | 5 | 3 | 0 | 57 | 0 | 0 | 0 | 79.2 | 81 | 46 | 42 | 32 | 62 | 5 | 6 |
| Lee Gronkiewicz |   | mr | 28 | 2.25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4.0 | 2 | 1 | 1 | 2 | 2 | 1 | 1 |
| Eddie Guardado* |   | mr | 36 | 7.24 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 13.2 | 16 | 11 | 11 | 4 | 8 | 2 | 0 |
| Matt Guerrier | MID | mr | 28 | 2.35 | 2 | 4 | 1 | 73 | 0 | 0 | 0 | 88.0 | 71 | 23 | 23 | 21 | 68 | 9 | 7 |
| Jeremy Guthrie | MID | sp | 28 | 3.70 | 7 | 5 | 0 | 32 | 26 | 0 | 0 | 175.1 | 165 | 78 | 72 | 47 | 123 | 23 | 18 |
| Juan Gutierrez |   | mr | 23 | 5.91 | 1 | 1 | 0 | 7 | 3 | 0 | 0 | 21.1 | 25 | 14 | 14 | 6 | 16 | 3 | 1 |
| Angel Guzman |   | mr | 25 | 3.56 | 0 | 1 | 0 | 12 | 3 | 0 | 0 | 30.1 | 32 | 12 | 12 | 9 | 26 | 2 | 5 |
| Marc Gwyn |   | cl | 29 | 11.81 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 5.1 | 9 | 9 | 7 | 5 | 3 | 3 | 0 |
| Charlie Haeger |   | mr | 23 | 7.15 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 11.1 | 17 | 11 | 9 | 8 | 1 | 3 | 1 |
| Roy Halladay | ROK | sp | 30 | 3.71 | 16 | 7 | 0 | 31 | 31 | 7 | 1 | 225.1 | 232 | 101 | 93 | 48 | 139 | 15 | 28 |
| Cole Hamels* | BT | sp | 23 | 3.39 | 15 | 5 | 0 | 28 | 28 | 2 | 0 | 183.1 | 163 | 72 | 69 | 43 | 177 | 25 | 12 |
| Jason Hammel | EDG | sp | 24 | 6.14 | 3 | 5 | 0 | 24 | 14 | 0 | 0 | 85.0 | 100 | 58 | 58 | 40 | 64 | 12 | 6 |
| Justin Hampson* | CCL | mr | 27 | 2.70 | 2 | 3 | 0 | 39 | 0 | 0 | 0 | 53.1 | 48 | 17 | 16 | 16 | 34 | 1 | 6 |
| Josh Hancock |   | mr | 29 | 3.55 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 12.2 | 14 | 6 | 5 | 5 | 9 | 2 | 1 |
| Joel Hanrahan | CCL | sp | 25 | 6.00 | 5 | 3 | 0 | 12 | 11 | 0 | 0 | 51.0 | 59 | 35 | 34 | 38 | 43 | 9 | 1 |
| Devern Hansack |   | mr | 29 | 4.70 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 7.2 | 9 | 5 | 4 | 5 | 5 | 2 | 0 |
| J.A. Happ* |   | sp | 24 | 11.25 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.0 | 7 | 5 | 5 | 2 | 5 | 3 | 1 |
| Aaron Harang | GEO | sp | 29 | 3.73 | 16 | 6 | 0 | 34 | 34 | 2 | 1 | 231.2 | 213 | 100 | 96 | 52 | 218 | 28 | 14 |
| Rich Harden | COP | sp | 25 | 2.45 | 1 | 2 | 0 | 7 | 4 | 0 | 0 | 25.2 | 18 | 7 | 7 | 11 | 27 | 3 | 5 |
| Dan Haren | LON | sp | 26 | 3.07 | 15 | 9 | 0 | 34 | 34 | 0 | 0 | 222.2 | 214 | 91 | 76 | 55 | 192 | 24 | 9 |
| Tim Harikkala |   | sp | 35 | 8.10 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 3.1 | 9 | 3 | 3 | 1 | 2 | 0 | 1 |
| Kevin Hart |   | mr | 24 | 0.82 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 11.0 | 7 | 1 | 1 | 4 | 13 | 0 | 1 |
| LaTroy Hawkins | BT | mr | 34 | 3.42 | 2 | 5 | 0 | 62 | 0 | 0 | 0 | 55.1 | 52 | 21 | 21 | 16 | 29 | 6 | 7 |
| Aaron Heilman | WIZ | mr | 28 | 3.03 | 7 | 7 | 1 | 81 | 0 | 0 | 0 | 86.0 | 72 | 36 | 29 | 20 | 63 | 8 | 4 |
| Mark Hendrickson* | MUL | mr | 33 | 5.21 | 4 | 8 | 0 | 39 | 15 | 0 | 0 | 122.2 | 142 | 75 | 71 | 29 | 92 | 15 | 9 |
| Sean Henn* |   | mr | 26 | 7.12 | 2 | 2 | 0 | 29 | 1 | 0 | 0 | 36.2 | 44 | 32 | 29 | 27 | 28 | 6 | 3 |
| Brad Hennessey |   | cl | 27 | 3.42 | 4 | 5 | 19 | 69 | 0 | 0 | 0 | 68.1 | 66 | 26 | 26 | 23 | 40 | 7 | 9 |
| Clay Hensley |   | sp | 27 | 6.84 | 2 | 3 | 0 | 13 | 9 | 0 | 0 | 50.0 | 62 | 40 | 38 | 32 | 30 | 5 | 4 |
| Matt Herges | LON | mr | 37 | 2.96 | 5 | 1 | 0 | 35 | 0 | 0 | 0 | 48.2 | 34 | 17 | 16 | 15 | 30 | 4 | 4 |
| Felix Hernandez | ROK | sp | 21 | 3.92 | 14 | 7 | 0 | 30 | 30 | 1 | 1 | 190.1 | 209 | 88 | 83 | 53 | 165 | 20 | 20 |
| Livan Hernandez |   | sp | 32 | 4.93 | 11 | 11 | 0 | 33 | 33 | 1 | 0 | 204.1 | 247 | 116 | 112 | 79 | 90 | 34 | 22 |
| Orlando Hernandez | Pal | sp | 37 | 3.72 | 9 | 5 | 0 | 27 | 24 | 0 | 0 | 147.2 | 109 | 64 | 61 | 64 | 128 | 23 | 9 |
| Roberto Hernandez |   | mr | 42 | 6.41 | 3 | 3 | 0 | 50 | 0 | 0 | 0 | 46.1 | 59 | 37 | 33 | 25 | 31 | 5 | 8 |
| Yoel Hernandez |   | mr | 27 | 5.28 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 15.1 | 20 | 9 | 9 | 1 | 13 | 2 | 0 |
| Rich Hill* | BT | sp | 27 | 3.92 | 11 | 8 | 0 | 32 | 32 | 0 | 0 | 195.0 | 170 | 89 | 85 | 63 | 183 | 27 | 14 |
| Shawn Hill | WIZ | sp | 26 | 3.42 | 4 | 5 | 0 | 16 | 16 | 0 | 0 | 97.1 | 86 | 42 | 37 | 25 | 65 | 9 | 8 |
| Jason Hirsh | WIZ | sp | 25 | 4.81 | 5 | 7 | 0 | 19 | 19 | 1 | 0 | 112.1 | 103 | 63 | 60 | 48 | 75 | 18 | 8 |
| Luke Hochevar |   | mr | 23 | 2.13 | 0 | 1 | 0 | 4 | 1 | 0 | 0 | 12.2 | 11 | 4 | 3 | 4 | 5 | 1 | 3 |
| Jim Hoey |   | mr | 24 | 7.30 | 3 | 4 | 0 | 23 | 0 | 0 | 0 | 24.2 | 25 | 21 | 20 | 18 | 18 | 2 | 3 |
| Trevor Hoffman | Pal | cl | 39 | 2.98 | 4 | 5 | 42 | 61 | 0 | 0 | 0 | 57.1 | 49 | 21 | 19 | 15 | 44 | 2 | 2 |
| D.J. Houlton |   | mr | 27 | 4.18 | 0 | 2 | 0 | 18 | 0 | 0 | 0 | 28.0 | 28 | 14 | 13 | 7 | 21 | 5 | 3 |
| J.P. Howell* | MID | sp | 24 | 7.59 | 1 | 6 | 0 | 10 | 10 | 0 | 0 | 51.0 | 69 | 45 | 43 | 21 | 49 | 8 | 5 |
| Bob Howry | COP | mr | 33 | 3.32 | 6 | 7 | 8 | 78 | 0 | 0 | 0 | 81.1 | 76 | 31 | 30 | 19 | 72 | 8 | 3 |
| Jon Huber |   | mr | 25 | 4.76 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 11.1 | 13 | 6 | 6 | 4 | 8 | 1 | 4 |
| Luke Hudson |   | sp | 30 | 18.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 2.0 | 2 | 5 | 4 | 4 | 0 | 1 | 0 |
| Tim Hudson | GEO | sp | 31 | 3.33 | 16 | 10 | 0 | 34 | 34 | 1 | 1 | 224.1 | 221 | 87 | 83 | 53 | 132 | 10 | 26 |
| Phil Hughes | COP | sp | 21 | 4.46 | 5 | 3 | 0 | 13 | 13 | 0 | 0 | 72.2 | 64 | 39 | 36 | 29 | 58 | 8 | 7 |
| Eric Hull |   | mr | 27 | 4.05 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.2 | 4 | 3 | 3 | 3 | 5 | 0 | 1 |
| Philip Humber |   | mr | 24 | 7.71 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 7.0 | 9 | 6 | 6 | 2 | 2 | 1 | 0 |
| Kei Igawa* |   | sp | 27 | 6.25 | 2 | 3 | 0 | 14 | 12 | 0 | 0 | 67.2 | 76 | 48 | 47 | 37 | 53 | 15 | 6 |
| Jason Isringhausen | Pal | cl | 34 | 2.48 | 4 | 0 | 32 | 63 | 0 | 0 | 0 | 65.1 | 42 | 21 | 18 | 28 | 54 | 4 | 5 |
| Edwin Jackson |   | sp | 23 | 5.76 | 5 | 15 | 0 | 32 | 31 | 1 | 1 | 161.0 | 195 | 116 | 103 | 88 | 128 | 19 | 12 |
| Chuck James* |   | sp | 25 | 4.24 | 11 | 10 | 0 | 30 | 30 | 0 | 0 | 161.1 | 164 | 77 | 76 | 58 | 116 | 32 | 7 |
| Casey Janssen | OTR | mr | 25 | 2.35 | 2 | 3 | 6 | 70 | 0 | 0 | 0 | 72.2 | 67 | 22 | 19 | 20 | 39 | 4 | 10 |
| Bobby Jenks | OTR | cl | 26 | 2.77 | 3 | 5 | 40 | 66 | 0 | 0 | 0 | 65.0 | 45 | 20 | 20 | 13 | 56 | 2 | 4 |
| Jason Jennings |   | sp | 28 | 6.45 | 2 | 9 | 0 | 19 | 18 | 0 | 0 | 99.0 | 119 | 73 | 71 | 34 | 71 | 19 | 6 |
| Kelvin Jimenez |   | mr | 26 | 7.50 | 3 | 0 | 0 | 34 | 0 | 0 | 0 | 42.0 | 56 | 36 | 35 | 17 | 24 | 2 | 6 |
| Ubaldo Jimenez | TON | sp | 23 | 4.28 | 4 | 4 | 0 | 15 | 15 | 0 | 0 | 82.0 | 70 | 46 | 39 | 37 | 68 | 10 | 7 |
| Jim Johnson |   | mr | 24 | 9.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 3 | 2 | 2 | 2 | 1 | 0 | 0 |
| Josh Johnson | LON | sp | 23 | 7.47 | 0 | 3 | 0 | 4 | 4 | 0 | 0 | 15.2 | 26 | 17 | 13 | 12 | 14 | 1 | 3 |
| Randy Johnson* | ROK | sp | 43 | 3.81 | 4 | 3 | 0 | 10 | 10 | 0 | 0 | 56.2 | 52 | 26 | 24 | 13 | 72 | 7 | 3 |
| Tyler Johnson* |   | mr | 26 | 4.03 | 1 | 1 | 0 | 55 | 0 | 0 | 0 | 38.0 | 31 | 18 | 17 | 16 | 24 | 4 | 2 |
| Greg Jones |   | mr | 30 | 6.23 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 8.2 | 10 | 6 | 6 | 5 | 5 | 2 | 0 |
| Todd Jones | MUL | cl | 39 | 4.26 | 1 | 4 | 38 | 63 | 0 | 0 | 0 | 61.1 | 64 | 29 | 29 | 23 | 33 | 3 | 7 |
| Jorge Julio |   | mr | 28 | 5.23 | 0 | 5 | 0 | 68 | 0 | 0 | 0 | 62.0 | 68 | 39 | 36 | 31 | 56 | 8 | 8 |
| Jair Jurrjens |   | sp | 21 | 4.70 | 3 | 1 | 0 | 7 | 7 | 0 | 0 | 30.2 | 24 | 16 | 16 | 11 | 13 | 4 | 4 |
| Jeff Karstens |   | mr | 24 | 11.05 | 1 | 4 | 0 | 7 | 3 | 0 | 0 | 14.2 | 27 | 21 | 18 | 9 | 5 | 4 | 0 |
| Scott Kazmir* | GEO | sp | 23 | 3.48 | 13 | 9 | 0 | 34 | 34 | 0 | 0 | 206.2 | 196 | 91 | 80 | 89 | 239 | 18 | 18 |
| Randy Keisler* |   | sp | 31 | 5.19 | 0 | 0 | 0 | 4 | 3 | 0 | 0 | 17.1 | 21 | 12 | 10 | 5 | 5 | 3 | 1 |
| Kyle Kendrick |   | sp | 22 | 3.87 | 10 | 4 | 0 | 20 | 20 | 0 | 0 | 121.0 | 129 | 53 | 52 | 25 | 49 | 16 | 17 |
| Ian Kennedy |   | sp | 22 | 1.89 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 19.0 | 13 | 6 | 4 | 9 | 15 | 1 | 1 |
| Joe Kennedy* |   | mr | 28 | 4.80 | 4 | 9 | 0 | 39 | 16 | 0 | 0 | 110.2 | 119 | 66 | 59 | 55 | 51 | 9 | 15 |
| Logan Kensing |   | mr | 24 | 1.35 | 3 | 0 | 0 | 9 | 0 | 0 | 0 | 13.1 | 11 | 2 | 2 | 7 | 13 | 0 | 1 |
| Bobby Keppel |   | mr | 25 | 11.25 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 6 | 5 | 5 | 3 | 1 | 1 | 1 |
| Byung-Hyun Kim |   | sp | 28 | 6.08 | 10 | 8 | 0 | 28 | 22 | 0 | 0 | 118.1 | 131 | 90 | 80 | 68 | 107 | 20 | 7 |
| Ray King* |   | mr | 33 | 4.76 | 1 | 1 | 0 | 67 | 0 | 0 | 0 | 39.2 | 37 | 21 | 21 | 21 | 25 | 6 | 3 |
| Steve Kline* |   | mr | 34 | 4.70 | 1 | 2 | 2 | 68 | 0 | 0 | 0 | 46.0 | 58 | 25 | 24 | 18 | 17 | 2 | 2 |
| Dan Kolb |   | mr | 32 | 9.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.0 | 6 | 3 | 3 | 2 | 2 | 1 | 1 |
| Shane Komine |   | mr | 26 | 4.70 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 7.2 | 6 | 4 | 4 | 1 | 1 | 2 | 0 |
| Mike Koplove |   | mr | 30 | 6.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.0 | 6 | 4 | 4 | 2 | 4 | 0 | 1 |
| John Koronka* |   | sp | 26 | 7.84 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 10.1 | 16 | 9 | 9 | 5 | 2 | 0 | 0 |
| Hong-Chih Kuo* | Pal | sp | 25 | 7.42 | 1 | 4 | 0 | 8 | 6 | 0 | 0 | 30.1 | 35 | 26 | 25 | 14 | 27 | 3 | 1 |
| Masumi Kuwata |   | mr | 39 | 9.43 | 0 | 1 | 0 | 19 | 0 | 0 | 0 | 21.0 | 25 | 23 | 22 | 15 | 12 | 6 | 2 |
| John Lackey | COP | sp | 28 | 3.01 | 19 | 9 | 0 | 33 | 33 | 2 | 2 | 224.0 | 219 | 87 | 75 | 52 | 179 | 18 | 23 |
| Aaron Laffey* | EDG | sp | 22 | 4.56 | 4 | 2 | 0 | 9 | 9 | 0 | 0 | 49.1 | 54 | 26 | 25 | 12 | 25 | 2 | 8 |
| John Lannan* |   | sp | 22 | 4.15 | 2 | 2 | 0 | 6 | 6 | 0 | 0 | 34.2 | 36 | 17 | 16 | 17 | 10 | 3 | 7 |
| Juan Lara* |   | mr | 26 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 2 | 2 | 2 | 1 | 2 | 1 | 0 |
| Brian Lawrence |   | sp | 31 | 6.83 | 1 | 2 | 0 | 6 | 6 | 0 | 0 | 29.0 | 43 | 22 | 22 | 13 | 18 | 4 | 3 |
| Brandon League |   | mr | 24 | 6.17 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 11.2 | 19 | 8 | 8 | 7 | 7 | 1 | 1 |
| Wilfredo Ledezma* |   | mr | 26 | 5.61 | 3 | 3 | 0 | 44 | 1 | 0 | 0 | 59.1 | 70 | 42 | 37 | 38 | 47 | 7 | 6 |
| Cliff Lee* | MID | sp | 28 | 6.29 | 5 | 8 | 0 | 20 | 16 | 1 | 0 | 97.1 | 112 | 73 | 68 | 36 | 66 | 17 | 7 |
| Jon Leicester |   | sp | 28 | 7.59 | 2 | 3 | 0 | 10 | 5 | 1 | 0 | 32.0 | 36 | 27 | 27 | 13 | 16 | 3 | 2 |
| Anthony Lerew |   | sp | 24 | 7.71 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 11.2 | 14 | 10 | 10 | 7 | 9 | 4 | 1 |
| Jon Lester* | EDG | sp | 23 | 4.57 | 4 | 0 | 0 | 12 | 11 | 0 | 0 | 63.0 | 61 | 33 | 32 | 31 | 50 | 10 | 3 |
| Colby Lewis |   | mr | 27 | 6.45 | 0 | 2 | 0 | 26 | 1 | 0 | 0 | 37.2 | 44 | 28 | 27 | 14 | 23 | 7 | 5 |
| Jensen Lewis |   | mr | 23 | 2.15 | 1 | 1 | 0 | 26 | 0 | 0 | 0 | 29.1 | 26 | 8 | 7 | 10 | 34 | 1 | 0 |
| Brad Lidge | Pal | cl | 30 | 3.36 | 5 | 3 | 19 | 66 | 0 | 0 | 0 | 67.0 | 54 | 29 | 25 | 30 | 88 | 9 | 3 |
| Jon Lieber | MUL | sp | 37 | 4.73 | 3 | 6 | 0 | 14 | 12 | 1 | 1 | 78.0 | 91 | 44 | 41 | 22 | 54 | 7 | 10 |
| Ted Lilly* | OTR | sp | 31 | 3.83 | 15 | 8 | 0 | 34 | 34 | 0 | 0 | 207.0 | 181 | 91 | 88 | 55 | 174 | 28 | 13 |
| Tim Lincecum | WIZ | sp | 23 | 4.00 | 7 | 5 | 0 | 24 | 24 | 0 | 0 | 146.1 | 122 | 70 | 65 | 65 | 150 | 12 | 9 |
| Matt Lindstrom | MUL | mr | 27 | 3.09 | 3 | 4 | 0 | 71 | 0 | 0 | 0 | 67.0 | 66 | 27 | 23 | 21 | 62 | 2 | 5 |
| Scott Linebrink |   | mr | 30 | 3.71 | 5 | 6 | 1 | 71 | 0 | 0 | 0 | 70.1 | 68 | 33 | 29 | 25 | 50 | 12 | 5 |
| Jesse Litsch | EDG | sp | 22 | 3.81 | 7 | 9 | 0 | 20 | 20 | 0 | 0 | 111.0 | 116 | 56 | 47 | 36 | 50 | 14 | 17 |
| Wes Littleton |   | mr | 24 | 4.31 | 3 | 2 | 2 | 35 | 0 | 0 | 0 | 48.0 | 48 | 23 | 23 | 16 | 24 | 6 | 6 |
| Bobby Livingston* |   | sp | 24 | 5.27 | 3 | 3 | 0 | 10 | 10 | 0 | 0 | 56.1 | 77 | 35 | 33 | 8 | 27 | 8 | 5 |
| Radhames Liz |   | mr | 24 | 6.93 | 0 | 2 | 0 | 9 | 4 | 0 | 0 | 24.2 | 25 | 21 | 19 | 23 | 24 | 3 | 0 |
| Esteban Loaiza |   | sp | 35 | 5.79 | 2 | 4 | 0 | 7 | 7 | 0 | 0 | 37.1 | 36 | 24 | 24 | 20 | 20 | 10 | 4 |
| Kameron Loe |   | sp | 25 | 5.36 | 6 | 11 | 0 | 28 | 23 | 0 | 0 | 136.0 | 162 | 96 | 81 | 56 | 78 | 13 | 14 |
| Adam Loewen* |   | sp | 23 | 3.56 | 2 | 0 | 0 | 6 | 6 | 0 | 0 | 30.1 | 27 | 14 | 12 | 26 | 22 | 1 | 5 |
| Boone Logan* |   | mr | 22 | 4.97 | 2 | 1 | 0 | 68 | 0 | 0 | 0 | 50.2 | 59 | 30 | 28 | 20 | 35 | 7 | 7 |
| Kyle Lohse | COP | sp | 28 | 4.62 | 9 | 12 | 0 | 34 | 32 | 2 | 1 | 192.2 | 207 | 109 | 99 | 57 | 122 | 22 | 13 |
| Braden Looper | MAD | sp | 32 | 4.94 | 12 | 12 | 0 | 31 | 30 | 0 | 0 | 175.0 | 183 | 100 | 96 | 51 | 87 | 22 | 16 |
| Aquilino Lopez |   | mr | 32 | 5.19 | 0 | 0 | 1 | 10 | 0 | 0 | 0 | 17.1 | 18 | 10 | 10 | 6 | 7 | 2 | 2 |
| Javier Lopez* | OTR | mr | 29 | 3.10 | 2 | 1 | 0 | 61 | 0 | 0 | 0 | 40.2 | 36 | 16 | 14 | 18 | 26 | 2 | 5 |
| Rodrigo Lopez | CCL | sp | 31 | 4.42 | 5 | 4 | 0 | 14 | 14 | 0 | 0 | 79.1 | 83 | 43 | 39 | 21 | 43 | 11 | 5 |
| Derek Lowe | BON | sp | 34 | 3.88 | 12 | 14 | 0 | 33 | 32 | 3 | 0 | 199.1 | 194 | 100 | 86 | 59 | 147 | 20 | 21 |
| Mark Lowe |   | mr | 24 | 6.75 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 2.2 | 2 | 2 | 2 | 3 | 3 | 1 | 0 |
| Noah Lowry* |   | sp | 26 | 3.92 | 14 | 8 | 0 | 26 | 26 | 1 | 0 | 156.0 | 155 | 76 | 68 | 87 | 87 | 12 | 25 |
| Ruddy Lugo |   | mr | 27 | 5.40 | 6 | 0 | 0 | 38 | 0 | 0 | 0 | 48.1 | 48 | 29 | 29 | 37 | 34 | 3 | 2 |
| Brandon Lyon | Pal | mr | 27 | 2.68 | 6 | 4 | 2 | 73 | 0 | 0 | 0 | 74.0 | 70 | 25 | 22 | 22 | 40 | 2 | 7 |
| Mike MacDougal |   | mr | 30 | 6.80 | 2 | 5 | 0 | 54 | 0 | 0 | 0 | 42.1 | 50 | 37 | 32 | 33 | 39 | 3 | 6 |
| Greg Maddux | Pal | sp | 41 | 4.14 | 14 | 11 | 0 | 34 | 34 | 1 | 0 | 198.0 | 221 | 92 | 91 | 25 | 104 | 14 | 14 |
| Ryan Madson | CCL | mr | 26 | 3.05 | 2 | 2 | 1 | 38 | 0 | 0 | 0 | 56.0 | 48 | 19 | 19 | 23 | 43 | 5 | 1 |
| Ron Mahay* |   | mr | 36 | 2.55 | 3 | 0 | 1 | 58 | 0 | 0 | 0 | 67.0 | 52 | 20 | 19 | 37 | 55 | 4 | 7 |
| Paul Maholm* |   | sp | 25 | 5.02 | 10 | 15 | 0 | 29 | 29 | 2 | 1 | 177.2 | 204 | 110 | 99 | 49 | 105 | 22 | 29 |
| John Maine | BT | sp | 26 | 3.91 | 15 | 10 | 0 | 32 | 32 | 1 | 1 | 191.0 | 168 | 90 | 83 | 75 | 180 | 23 | 5 |
| Gary Majewski |   | mr | 27 | 8.22 | 0 | 4 | 0 | 32 | 0 | 0 | 0 | 23.0 | 43 | 22 | 21 | 3 | 10 | 3 | 4 |
| Shaun Marcum | COP | sp | 25 | 4.13 | 12 | 6 | 1 | 38 | 25 | 0 | 0 | 159.0 | 149 | 76 | 73 | 49 | 122 | 27 | 16 |
| Carlos Marmol | WIZ | mr | 24 | 1.43 | 5 | 1 | 1 | 59 | 0 | 0 | 0 | 69.1 | 41 | 11 | 11 | 35 | 96 | 3 | 2 |
| Mike Maroth* |   | sp | 29 | 6.89 | 5 | 7 | 0 | 27 | 20 | 0 | 0 | 116.1 | 168 | 103 | 89 | 50 | 51 | 26 | 14 |
| Jason Marquis | MUL | sp | 28 | 4.60 | 12 | 9 | 0 | 34 | 33 | 1 | 1 | 191.2 | 190 | 111 | 98 | 76 | 109 | 22 | 19 |
| Jay Marshall* |   | mr | 24 | 6.43 | 1 | 2 | 0 | 51 | 0 | 0 | 0 | 42.0 | 50 | 33 | 30 | 22 | 18 | 3 | 7 |
| Sean Marshall* | LON | sp | 24 | 3.92 | 7 | 8 | 0 | 21 | 19 | 0 | 0 | 103.1 | 107 | 52 | 45 | 35 | 67 | 13 | 9 |
| Damaso Marte* | WIZ | mr | 32 | 2.38 | 2 | 0 | 0 | 65 | 0 | 0 | 0 | 45.1 | 32 | 14 | 12 | 18 | 51 | 2 | 4 |
| Tom Martin* |   | mr | 37 | 4.91 | 0 | 0 | 0 | 26 | 0 | 0 | 0 | 25.2 | 32 | 14 | 14 | 9 | 10 | 4 | 1 |
| Carlos Martinez |   | mr | 25 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 4 | 4 | 4 | 1 | 2 | 3 | 0 |
| Pedro Martinez |   | sp | 35 | 2.57 | 3 | 1 | 0 | 5 | 5 | 0 | 0 | 28.0 | 33 | 11 | 8 | 7 | 32 | 0 | 1 |
| Nick Masset |   | mr | 25 | 7.09 | 2 | 3 | 0 | 27 | 1 | 0 | 0 | 39.1 | 52 | 33 | 31 | 26 | 21 | 2 | 5 |
| Tom Mastny |   | mr | 26 | 4.68 | 7 | 2 | 0 | 51 | 0 | 0 | 0 | 57.2 | 63 | 30 | 30 | 32 | 52 | 6 | 5 |
| Julio Mateo |   | mr | 29 | 3.75 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 12.0 | 12 | 5 | 5 | 5 | 4 | 0 | 1 |
| Daisuke Matsuzaka | OTR | sp | 26 | 4.40 | 15 | 12 | 0 | 32 | 32 | 1 | 0 | 204.2 | 191 | 100 | 100 | 80 | 201 | 25 | 17 |
| Marcus McBeth |   | mr | 26 | 5.95 | 3 | 2 | 0 | 23 | 0 | 0 | 0 | 19.2 | 22 | 13 | 13 | 7 | 17 | 2 | 0 |
| Macay McBride* |   | mr | 24 | 4.96 | 1 | 1 | 0 | 38 | 0 | 0 | 0 | 32.2 | 33 | 21 | 18 | 25 | 30 | 4 | 3 |
| Brandon McCarthy | EDG | sp | 23 | 4.87 | 5 | 10 | 0 | 23 | 22 | 0 | 0 | 101.2 | 111 | 62 | 55 | 48 | 59 | 9 | 7 |
| Zach McClellan |   | mr | 28 | 5.79 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 14.0 | 20 | 9 | 9 | 5 | 13 | 0 | 3 |
| Seth McClung |   | mr | 26 | 3.75 | 0 | 1 | 0 | 14 | 0 | 0 | 0 | 12.0 | 11 | 9 | 5 | 5 | 11 | 0 | 3 |
| Dustin McGowan | OTR | sp | 25 | 4.08 | 12 | 10 | 0 | 27 | 27 | 2 | 1 | 169.2 | 146 | 80 | 77 | 61 | 144 | 14 | 13 |
| Marty McLeary |   | mr | 32 | 8.22 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 7.2 | 9 | 8 | 7 | 2 | 5 | 4 | 0 |
| Mark McLemore* |   | mr | 26 | 3.86 | 3 | 0 | 0 | 29 | 0 | 0 | 0 | 35.0 | 38 | 17 | 15 | 18 | 35 | 5 | 0 |
| Gil Meche | CRH | sp | 28 | 3.67 | 9 | 13 | 0 | 34 | 34 | 1 | 0 | 216.0 | 218 | 98 | 88 | 62 | 156 | 22 | 20 |
| Brandon Medders |   | mr | 27 | 4.30 | 1 | 2 | 0 | 30 | 0 | 0 | 0 | 29.1 | 30 | 16 | 14 | 16 | 23 | 9 | 1 |
| Jonathan Meloan |   | mr | 22 | 11.05 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 7.1 | 8 | 9 | 9 | 8 | 7 | 1 | 0 |
| Luis Mendoza |   | sp | 23 | 2.25 | 1 | 0 | 0 | 6 | 3 | 0 | 0 | 16.0 | 13 | 4 | 4 | 4 | 7 | 1 | 1 |
| Cla Meredith |   | mr | 24 | 3.50 | 5 | 6 | 0 | 80 | 0 | 0 | 0 | 79.2 | 94 | 38 | 31 | 17 | 59 | 6 | 14 |
| Jose Mesa |   | mr | 41 | 7.11 | 2 | 3 | 1 | 56 | 0 | 0 | 0 | 50.2 | 53 | 48 | 40 | 25 | 29 | 9 | 6 |
| Randy Messenger |   | mr | 25 | 4.20 | 2 | 4 | 1 | 60 | 0 | 0 | 0 | 64.1 | 85 | 30 | 30 | 21 | 34 | 4 | 8 |
| Dan Meyer* |   | sp | 25 | 8.82 | 0 | 2 | 0 | 6 | 3 | 0 | 0 | 16.1 | 20 | 19 | 16 | 9 | 11 | 2 | 0 |
| Andrew Miller* | GEO | sp | 22 | 5.63 | 5 | 5 | 0 | 13 | 13 | 0 | 0 | 64.0 | 73 | 43 | 40 | 39 | 56 | 8 | 5 |
| Jason Miller* |   | mr | 24 | 18.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 7 | 8 | 8 | 3 | 2 | 2 | 0 |
| Justin Miller |   | mr | 29 | 3.65 | 5 | 0 | 0 | 62 | 0 | 0 | 0 | 61.2 | 53 | 27 | 25 | 24 | 74 | 5 | 3 |
| Matt Miller |   | mr | 35 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Trever Miller* |   | mr | 34 | 4.86 | 0 | 0 | 1 | 76 | 0 | 0 | 0 | 46.1 | 45 | 26 | 25 | 23 | 46 | 6 | 2 |
| Wade Miller |   | sp | 30 | 10.54 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 13.2 | 24 | 16 | 16 | 6 | 6 | 5 | 0 |
| Kevin Millwood |   | sp | 32 | 5.16 | 10 | 14 | 0 | 31 | 31 | 0 | 0 | 172.2 | 213 | 111 | 99 | 67 | 123 | 19 | 18 |
| Eric Milton* |   | sp | 31 | 5.17 | 0 | 4 | 0 | 6 | 6 | 0 | 0 | 31.1 | 39 | 21 | 18 | 9 | 18 | 4 | 2 |
| Zach Miner |   | mr | 25 | 3.02 | 3 | 4 | 0 | 34 | 1 | 0 | 0 | 53.2 | 56 | 22 | 18 | 22 | 34 | 3 | 6 |
| Patrick Misch* |   | mr | 25 | 4.24 | 0 | 4 | 0 | 18 | 4 | 0 | 0 | 40.1 | 47 | 21 | 19 | 12 | 26 | 3 | 6 |
| Sergio Mitre |   | sp | 26 | 4.65 | 5 | 8 | 0 | 27 | 27 | 0 | 0 | 149.0 | 180 | 88 | 77 | 41 | 80 | 9 | 18 |
| Brian Moehler |   | mr | 35 | 4.07 | 1 | 4 | 1 | 42 | 0 | 0 | 0 | 59.2 | 67 | 29 | 27 | 17 | 36 | 8 | 11 |
| Franklin Morales* |   | sp | 21 | 3.43 | 3 | 2 | 0 | 8 | 8 | 0 | 0 | 39.1 | 34 | 15 | 15 | 14 | 26 | 2 | 4 |
| Juan Morillo |   | mr | 23 | 9.82 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.2 | 3 | 4 | 4 | 1 | 3 | 1 | 0 |
| Matt Morris |   | sp | 32 | 4.89 | 10 | 11 | 0 | 32 | 32 | 3 | 0 | 198.2 | 240 | 123 | 108 | 61 | 102 | 18 | 24 |
| Brandon Morrow | CRH | mr | 22 | 4.12 | 3 | 4 | 0 | 60 | 0 | 0 | 0 | 63.1 | 56 | 29 | 29 | 50 | 66 | 3 | 4 |
| Dustin Moseley |   | mr | 25 | 4.40 | 4 | 3 | 0 | 46 | 8 | 0 | 0 | 92.0 | 97 | 45 | 45 | 27 | 50 | 7 | 13 |
| Guillermo Mota |   | mr | 33 | 5.76 | 2 | 2 | 0 | 52 | 0 | 0 | 0 | 59.1 | 63 | 39 | 38 | 18 | 47 | 8 | 2 |
| Jamie Moyer* |   | sp | 44 | 5.01 | 14 | 12 | 0 | 33 | 33 | 1 | 0 | 199.1 | 222 | 118 | 111 | 66 | 133 | 30 | 18 |
| Peter Moylan | MAD | mr | 28 | 1.80 | 5 | 3 | 1 | 80 | 0 | 0 | 0 | 90.0 | 65 | 27 | 18 | 31 | 63 | 6 | 12 |
| Edward Mujica |   | mr | 23 | 8.31 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 13.0 | 19 | 12 | 12 | 2 | 7 | 3 | 0 |
| Mark Mulder* |   | sp | 29 | 12.27 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 11.0 | 22 | 17 | 15 | 7 | 3 | 4 | 4 |
| Carlos Muniz |   | mr | 26 | 7.71 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 1 | 2 | 2 | 2 | 2 | 0 | 0 |
| Arnie Munoz* |   | mr | 25 | 6.75 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 5.1 | 6 | 4 | 4 | 7 | 3 | 2 | 0 |
| Scott Munter |   | mr | 27 | 4.22 | 1 | 1 | 0 | 12 | 0 | 0 | 0 | 10.2 | 14 | 5 | 5 | 4 | 4 | 0 | 3 |
| Bill Murphy* |   | mr | 26 | 5.68 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 6.1 | 9 | 4 | 4 | 7 | 2 | 0 | 1 |
| A.J. Murray* |   | mr | 25 | 4.50 | 1 | 2 | 0 | 14 | 2 | 0 | 0 | 28.0 | 25 | 15 | 14 | 15 | 18 | 6 | 1 |
| Neal Musser* |   | mr | 26 | 4.38 | 0 | 1 | 0 | 17 | 0 | 0 | 0 | 24.2 | 32 | 13 | 12 | 14 | 19 | 5 | 3 |
| Mike Mussina |   | sp | 38 | 5.15 | 11 | 10 | 0 | 28 | 27 | 0 | 0 | 152.0 | 188 | 90 | 87 | 35 | 91 | 14 | 18 |
| Brett Myers | CRH | cl | 26 | 4.33 | 5 | 7 | 21 | 51 | 3 | 0 | 0 | 68.2 | 61 | 33 | 33 | 27 | 83 | 9 | 1 |
| Mike Myers* |   | mr | 38 | 4.80 | 4 | 0 | 0 | 72 | 0 | 0 | 0 | 54.1 | 59 | 33 | 29 | 23 | 27 | 6 | 7 |
| Joe Nathan | WIZ | cl | 32 | 1.88 | 4 | 2 | 37 | 68 | 0 | 0 | 0 | 71.2 | 54 | 15 | 15 | 19 | 77 | 4 | 4 |
| Pat Neshek | BON | mr | 26 | 2.94 | 7 | 2 | 0 | 74 | 0 | 0 | 0 | 70.1 | 44 | 25 | 23 | 27 | 74 | 7 | 4 |
| Josh Newman* |   | mr | 25 | 4.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 1 | 1 | 0 | 3 | 0 | 0 |
| Dustin Nippert |   | mr | 26 | 5.56 | 1 | 1 | 0 | 36 | 0 | 0 | 0 | 45.1 | 48 | 30 | 28 | 16 | 38 | 5 | 5 |
| Ricky Nolasco |   | sp | 24 | 5.48 | 1 | 2 | 0 | 5 | 4 | 0 | 0 | 21.1 | 26 | 16 | 13 | 9 | 11 | 3 | 0 |
| Leo Nunez |   | mr | 23 | 3.92 | 2 | 4 | 0 | 13 | 6 | 0 | 0 | 43.2 | 44 | 21 | 19 | 10 | 37 | 8 | 4 |
| Eric O'Flaherty* | CRH | mr | 22 | 4.47 | 7 | 1 | 0 | 56 | 0 | 0 | 0 | 52.1 | 45 | 26 | 26 | 20 | 36 | 1 | 4 |
| Wes Obermueller |   | mr | 30 | 6.56 | 2 | 3 | 0 | 18 | 7 | 0 | 0 | 59.0 | 72 | 49 | 43 | 36 | 35 | 7 | 9 |
| Tomo Ohka |   | sp | 31 | 5.79 | 2 | 5 | 0 | 10 | 10 | 0 | 0 | 56.0 | 68 | 39 | 36 | 22 | 21 | 10 | 7 |
| Ross Ohlendorf |   | mr | 24 | 2.84 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 6.1 | 5 | 2 | 2 | 2 | 9 | 1 | 0 |
| Will Ohman* | MAD | mr | 29 | 4.95 | 2 | 4 | 1 | 56 | 0 | 0 | 0 | 36.1 | 42 | 20 | 20 | 16 | 33 | 3 | 2 |
| Hideki Okajima* | COP | mr | 31 | 2.22 | 3 | 2 | 5 | 66 | 0 | 0 | 0 | 69.0 | 50 | 17 | 17 | 17 | 63 | 6 | 6 |
| Darren Oliver* |   | mr | 36 | 3.78 | 3 | 1 | 0 | 61 | 0 | 0 | 0 | 64.1 | 58 | 31 | 27 | 23 | 51 | 5 | 5 |
| Scott Olsen* |   | sp | 23 | 5.81 | 10 | 15 | 0 | 33 | 33 | 0 | 0 | 176.2 | 226 | 134 | 114 | 85 | 133 | 29 | 17 |
| Garrett Olson* |   | sp | 23 | 7.79 | 1 | 3 | 0 | 7 | 7 | 0 | 0 | 32.1 | 42 | 28 | 28 | 28 | 28 | 4 | 6 |
| Ramon Ortiz |   | mr | 34 | 5.45 | 5 | 4 | 0 | 38 | 10 | 0 | 0 | 104.0 | 127 | 65 | 63 | 22 | 51 | 16 | 11 |
| Russ Ortiz |   | sp | 33 | 5.51 | 2 | 3 | 0 | 12 | 8 | 0 | 0 | 49.0 | 57 | 32 | 30 | 20 | 27 | 4 | 3 |
| Chad Orvella |   | mr | 26 | 14.63 | 0 | 2 | 0 | 10 | 0 | 0 | 0 | 8.0 | 18 | 16 | 13 | 10 | 6 | 3 | 0 |
| Franquelis Osoria |   | mr | 25 | 4.76 | 0 | 2 | 0 | 25 | 0 | 0 | 0 | 28.1 | 33 | 16 | 15 | 8 | 13 | 3 | 6 |
| Roy Oswalt | BT | sp | 29 | 3.18 | 14 | 7 | 0 | 33 | 32 | 1 | 0 | 212.0 | 221 | 80 | 75 | 60 | 154 | 14 | 19 |
| Akinori Otsuka |   | mr | 35 | 2.51 | 2 | 1 | 4 | 34 | 0 | 0 | 0 | 32.1 | 26 | 10 | 9 | 9 | 23 | 0 | 1 |
| Henry Owens |   | mr | 28 | 1.96 | 2 | 0 | 4 | 22 | 0 | 0 | 0 | 23.0 | 19 | 7 | 5 | 10 | 16 | 3 | 0 |
| Micah Owings |   | sp | 24 | 4.30 | 8 | 8 | 0 | 29 | 27 | 2 | 1 | 152.2 | 146 | 81 | 73 | 50 | 106 | 20 | 13 |
| Vicente Padilla |   | sp | 29 | 5.76 | 6 | 10 | 0 | 23 | 23 | 0 | 0 | 120.1 | 146 | 88 | 77 | 50 | 71 | 16 | 12 |
| Jonathan Papelbon | BON | cl | 26 | 1.85 | 1 | 3 | 37 | 59 | 0 | 0 | 0 | 58.1 | 30 | 12 | 12 | 15 | 84 | 5 | 1 |
| Chan Ho Park |   | sp | 34 | 15.75 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.0 | 6 | 7 | 7 | 2 | 4 | 2 | 0 |
| Chad Paronto |   | mr | 31 | 3.57 | 3 | 1 | 1 | 41 | 0 | 0 | 0 | 40.1 | 47 | 20 | 16 | 19 | 14 | 1 | 8 |
| Manny Parra* |   | mr | 24 | 3.76 | 0 | 1 | 0 | 9 | 2 | 0 | 0 | 26.1 | 25 | 13 | 11 | 12 | 26 | 1 | 3 |
| John Parrish* |   | mr | 29 | 5.71 | 2 | 2 | 0 | 53 | 0 | 0 | 0 | 52.0 | 63 | 34 | 33 | 37 | 41 | 2 | 4 |
| John Patterson |   | sp | 29 | 7.47 | 1 | 5 | 0 | 7 | 7 | 0 | 0 | 31.1 | 39 | 26 | 26 | 22 | 15 | 5 | 2 |
| Troy Patton* |   | sp | 21 | 3.55 | 0 | 2 | 0 | 3 | 2 | 0 | 0 | 12.2 | 10 | 6 | 5 | 4 | 8 | 3 | 1 |
| Felipe Paulino |   | sp | 23 | 7.11 | 2 | 1 | 0 | 5 | 3 | 0 | 0 | 19.0 | 22 | 15 | 15 | 7 | 11 | 5 | 2 |
| Carl Pavano |   | sp | 31 | 4.76 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 11.1 | 12 | 7 | 6 | 2 | 4 | 1 | 3 |
| Jake Peavy | MUL | sp | 26 | 2.54 | 19 | 6 | 0 | 34 | 34 | 0 | 0 | 223.1 | 169 | 67 | 63 | 68 | 240 | 13 | 16 |
| Jailen Peguero |   | mr | 26 | 9.20 | 1 | 0 | 0 | 18 | 0 | 0 | 0 | 14.2 | 17 | 15 | 15 | 13 | 9 | 2 | 1 |
| Mike Pelfrey |   | sp | 23 | 5.57 | 3 | 8 | 0 | 15 | 13 | 0 | 0 | 72.2 | 85 | 47 | 45 | 39 | 45 | 6 | 7 |
| Tony Pena | LON | mr | 25 | 3.27 | 5 | 4 | 2 | 75 | 0 | 0 | 0 | 85.1 | 63 | 36 | 31 | 31 | 63 | 8 | 11 |
| Brad Penny | LON | sp | 29 | 3.03 | 16 | 4 | 0 | 33 | 33 | 0 | 0 | 208.0 | 199 | 75 | 70 | 73 | 135 | 9 | 29 |
| Joel Peralta | MID | mr | 31 | 3.80 | 1 | 3 | 1 | 62 | 0 | 0 | 0 | 87.2 | 93 | 39 | 37 | 19 | 66 | 9 | 8 |
| Troy Percival | OTR | mr | 37 | 1.80 | 3 | 0 | 0 | 34 | 1 | 0 | 0 | 40.0 | 24 | 8 | 8 | 10 | 36 | 3 | 1 |
| Juan Perez* |   | mr | 28 | 4.38 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 12.1 | 14 | 7 | 6 | 8 | 10 | 2 | 2 |
| Odalis Perez* |   | sp | 30 | 5.57 | 8 | 11 | 0 | 26 | 26 | 0 | 0 | 137.1 | 178 | 90 | 85 | 50 | 64 | 14 | 16 |
| Oliver Perez* | BT | sp | 25 | 3.56 | 15 | 10 | 0 | 29 | 29 | 0 | 0 | 177.0 | 153 | 90 | 70 | 79 | 174 | 22 | 10 |
| Rafael Perez* | CRH | mr | 25 | 1.78 | 1 | 2 | 1 | 44 | 0 | 0 | 0 | 60.2 | 41 | 15 | 12 | 15 | 62 | 5 | 6 |
| Glen Perkins* |   | mr | 24 | 3.14 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 28.2 | 23 | 10 | 10 | 12 | 20 | 2 | 5 |
| Yusmeiro Petit |   | sp | 22 | 4.58 | 3 | 4 | 0 | 14 | 10 | 0 | 0 | 57.0 | 58 | 30 | 29 | 18 | 40 | 12 | 4 |
| Billy Petrick |   | mr | 23 | 7.45 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 9.2 | 8 | 8 | 8 | 7 | 6 | 3 | 1 |
| Andy Pettitte* |   | sp | 35 | 4.05 | 15 | 9 | 0 | 36 | 34 | 0 | 0 | 215.1 | 238 | 106 | 97 | 69 | 141 | 16 | 29 |
| Heath Phillips* |   | mr | 25 | 3.68 | 1 | 1 | 0 | 6 | 0 | 0 | 0 | 7.1 | 10 | 3 | 3 | 4 | 2 | 1 | 1 |
| Carmen Pignatiello* |   | mr | 24 | 4.50 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 2.0 | 3 | 1 | 1 | 0 | 3 | 1 | 0 |
| Joel Pineiro |   | mr | 28 | 4.33 | 7 | 5 | 0 | 42 | 11 | 0 | 0 | 97.2 | 110 | 49 | 47 | 26 | 60 | 14 | 8 |
| Renyel Pinto* |   | mr | 24 | 3.68 | 2 | 4 | 1 | 57 | 0 | 0 | 0 | 58.2 | 45 | 25 | 24 | 32 | 56 | 7 | 8 |
| Sidney Ponson |   | sp | 30 | 6.93 | 2 | 5 | 0 | 7 | 7 | 0 | 0 | 37.2 | 54 | 31 | 29 | 17 | 23 | 7 | 4 |
| Bret Prinz |   | mr | 30 | 8.10 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 4 | 3 | 3 | 2 | 1 | 1 | 0 |
| Scott Proctor |   | mr | 30 | 3.65 | 5 | 5 | 0 | 83 | 0 | 0 | 0 | 86.1 | 78 | 41 | 35 | 44 | 64 | 12 | 5 |
| J.J. Putz | MID | cl | 30 | 1.38 | 6 | 1 | 40 | 68 | 0 | 0 | 0 | 71.2 | 37 | 11 | 11 | 13 | 82 | 6 | 7 |
| Chad Qualls | BON | mr | 28 | 3.05 | 6 | 5 | 5 | 79 | 0 | 0 | 0 | 82.2 | 84 | 29 | 28 | 25 | 78 | 10 | 11 |
| Aaron Rakers |   | mr | 30 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Edwar Ramirez |   | mr | 26 | 8.14 | 1 | 1 | 1 | 21 | 0 | 0 | 0 | 21.0 | 24 | 19 | 19 | 14 | 31 | 6 | 0 |
| Elizardo Ramirez |   | sp | 24 | 7.71 | 0 | 2 | 0 | 4 | 3 | 0 | 0 | 16.1 | 20 | 14 | 14 | 8 | 8 | 5 | 2 |
| Erasmo Ramirez* |   | mr | 31 | 2.84 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 6.1 | 7 | 2 | 2 | 3 | 1 | 0 | 1 |
| Horacio Ramirez* |   | sp | 27 | 7.16 | 8 | 7 | 0 | 20 | 20 | 0 | 0 | 98.0 | 139 | 86 | 78 | 42 | 40 | 13 | 14 |
| Ramon Ramirez | LON | mr | 25 | 8.31 | 2 | 2 | 0 | 22 | 0 | 0 | 0 | 17.1 | 21 | 16 | 16 | 6 | 15 | 2 | 1 |
| Stephen Randolph* |   | mr | 33 | 12.15 | 0 | 1 | 0 | 14 | 0 | 0 | 0 | 13.1 | 21 | 19 | 18 | 17 | 22 | 4 | 1 |
| Clay Rapada* |   | mr | 26 | 10.13 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 2.2 | 3 | 3 | 3 | 2 | 4 | 2 | 0 |
| Darrell Rasner |   | sp | 26 | 4.01 | 1 | 3 | 0 | 6 | 6 | 0 | 0 | 24.2 | 29 | 14 | 11 | 8 | 11 | 4 | 1 |
| Jon Rauch | TON | mr | 28 | 3.61 | 8 | 4 | 4 | 88 | 0 | 0 | 0 | 87.1 | 75 | 37 | 35 | 21 | 71 | 7 | 6 |
| Chris Ray | MID | cl | 25 | 4.43 | 5 | 6 | 16 | 43 | 0 | 0 | 0 | 42.2 | 35 | 22 | 21 | 18 | 44 | 5 | 2 |
| Tim Redding | CCL | sp | 29 | 3.64 | 3 | 6 | 0 | 15 | 15 | 0 | 0 | 84.0 | 84 | 35 | 34 | 38 | 47 | 10 | 10 |
| Mark Redman* |   | sp | 33 | 7.62 | 2 | 4 | 0 | 11 | 8 | 0 | 0 | 41.1 | 59 | 37 | 35 | 17 | 27 | 6 | 2 |
| Chris Reitsma |   | mr | 29 | 7.61 | 0 | 2 | 0 | 26 | 0 | 0 | 0 | 23.2 | 37 | 22 | 20 | 9 | 11 | 3 | 3 |
| Chris Resop |   | mr | 24 | 4.15 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 4 | 2 | 2 | 1 | 2 | 1 | 1 |
| Al Reyes |   | cl | 37 | 4.90 | 2 | 4 | 26 | 61 | 0 | 0 | 0 | 60.2 | 49 | 35 | 33 | 21 | 70 | 13 | 0 |
| Anthony Reyes |   | sp | 25 | 6.04 | 2 | 14 | 0 | 22 | 20 | 1 | 0 | 107.1 | 108 | 77 | 72 | 43 | 74 | 16 | 6 |
| Dennys Reyes* |   | mr | 30 | 3.99 | 2 | 1 | 0 | 50 | 0 | 0 | 0 | 29.1 | 34 | 14 | 13 | 21 | 21 | 1 | 3 |
| Jo-Jo Reyes* |   | sp | 22 | 6.22 | 2 | 2 | 0 | 11 | 10 | 0 | 0 | 50.2 | 55 | 39 | 35 | 30 | 27 | 9 | 9 |
| John Rheinecker* |   | mr | 28 | 5.36 | 4 | 3 | 0 | 23 | 7 | 0 | 0 | 50.1 | 61 | 38 | 30 | 28 | 40 | 9 | 7 |
| Jeff Ridgway* |   | mr | 26 | 189.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.1 | 7 | 7 | 7 | 1 | 0 | 1 | 0 |
| Juan Rincon |   | mr | 28 | 5.13 | 3 | 3 | 0 | 63 | 0 | 0 | 0 | 59.2 | 65 | 38 | 34 | 28 | 49 | 9 | 3 |
| Royce Ring* |   | mr | 26 | 2.70 | 1 | 0 | 0 | 26 | 0 | 0 | 0 | 20.0 | 13 | 8 | 6 | 17 | 21 | 1 | 3 |
| David Riske | CRH | mr | 30 | 2.45 | 1 | 4 | 4 | 65 | 0 | 0 | 0 | 69.2 | 61 | 19 | 19 | 27 | 52 | 8 | 6 |
| Mariano Rivera | ROK | cl | 37 | 3.15 | 3 | 4 | 30 | 67 | 0 | 0 | 0 | 71.1 | 68 | 25 | 25 | 12 | 74 | 4 | 7 |
| Saul Rivera | BT | mr | 29 | 3.68 | 4 | 6 | 3 | 85 | 0 | 0 | 0 | 93.0 | 88 | 39 | 38 | 42 | 64 | 1 | 12 |
| Connor Robertson |   | mr | 25 | 18.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.0 | 6 | 4 | 4 | 2 | 2 | 0 | 0 |
| Nate Robertson* |   | sp | 29 | 4.76 | 9 | 13 | 0 | 30 | 30 | 0 | 0 | 177.2 | 199 | 98 | 94 | 63 | 119 | 22 | 15 |
| Fernando Rodney | OTR | mr | 30 | 4.26 | 2 | 6 | 1 | 48 | 0 | 0 | 0 | 50.2 | 46 | 27 | 24 | 21 | 54 | 5 | 3 |
| Francisco Rodriguez | BON | cl | 25 | 2.81 | 5 | 2 | 40 | 64 | 0 | 0 | 0 | 67.1 | 50 | 22 | 21 | 34 | 90 | 3 | 1 |
| Wandy Rodriguez* | MUL | sp | 28 | 4.58 | 9 | 13 | 0 | 31 | 31 | 1 | 1 | 182.2 | 179 | 102 | 93 | 62 | 158 | 22 | 10 |
| Brian Rogers |   | mr | 24 | 13.50 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.0 | 3 | 3 | 3 | 1 | 1 | 2 | 0 |
| Kenny Rogers* |   | sp | 42 | 4.43 | 3 | 4 | 0 | 11 | 11 | 0 | 0 | 63.0 | 65 | 36 | 31 | 25 | 36 | 8 | 6 |
| J.C. Romero* |   | mr | 31 | 1.92 | 2 | 2 | 1 | 74 | 0 | 0 | 0 | 56.1 | 39 | 12 | 12 | 40 | 42 | 3 | 11 |
| Francisco Rosario |   | mr | 26 | 5.47 | 0 | 3 | 1 | 23 | 0 | 0 | 0 | 26.1 | 34 | 16 | 16 | 13 | 25 | 3 | 1 |
| Ryan Rowland-Smith* |   | mr | 24 | 3.96 | 1 | 0 | 0 | 26 | 0 | 0 | 0 | 38.2 | 39 | 19 | 17 | 15 | 42 | 4 | 3 |
| B.J. Ryan* |   | cl | 31 | 12.46 | 0 | 2 | 3 | 5 | 0 | 0 | 0 | 4.1 | 7 | 7 | 6 | 4 | 3 | 1 | 0 |
| Jae Kuk Ryu |   | mr | 24 | 7.33 | 1 | 2 | 0 | 17 | 0 | 0 | 0 | 23.1 | 31 | 19 | 19 | 11 | 14 | 2 | 4 |
| Kirk Saarloos |   | mr | 28 | 7.17 | 1 | 5 | 0 | 34 | 3 | 0 | 0 | 42.2 | 54 | 36 | 34 | 19 | 27 | 8 | 7 |
| C.C. Sabathia* | CRH | sp | 26 | 3.21 | 19 | 7 | 0 | 34 | 34 | 4 | 1 | 241.0 | 238 | 94 | 86 | 37 | 209 | 20 | 23 |
| Takashi Saito | Pal | cl | 37 | 1.40 | 2 | 1 | 39 | 63 | 0 | 0 | 0 | 64.1 | 33 | 10 | 10 | 13 | 78 | 5 | 7 |
| Juan Salas |   | mr | 28 | 3.72 | 1 | 1 | 0 | 34 | 0 | 0 | 0 | 36.1 | 36 | 19 | 15 | 17 | 26 | 7 | 0 |
| Brad Salmon |   | mr | 27 | 4.13 | 0 | 1 | 0 | 26 | 0 | 0 | 0 | 24.0 | 22 | 11 | 11 | 10 | 22 | 3 | 3 |
| Chris Sampson |   | sp | 29 | 4.59 | 7 | 8 | 0 | 24 | 19 | 0 | 0 | 121.2 | 138 | 64 | 62 | 30 | 51 | 20 | 13 |
| Brian Sanches |   | mr | 28 | 5.52 | 1 | 1 | 0 | 12 | 0 | 0 | 0 | 14.2 | 13 | 11 | 9 | 12 | 9 | 6 | 1 |
| Anibal Sanchez | MAD | sp | 23 | 4.80 | 2 | 1 | 0 | 6 | 6 | 0 | 0 | 30.0 | 43 | 17 | 16 | 19 | 14 | 3 | 2 |
| Jonathan Sanchez* |   | mr | 24 | 5.88 | 1 | 5 | 0 | 33 | 4 | 0 | 0 | 52.0 | 57 | 34 | 34 | 28 | 62 | 8 | 4 |
| Romulo Sanchez |   | mr | 23 | 5.00 | 1 | 0 | 0 | 16 | 0 | 0 | 0 | 18.0 | 16 | 10 | 10 | 8 | 11 | 2 | 5 |
| Ervin Santana | BON | sp | 24 | 5.76 | 7 | 14 | 0 | 28 | 26 | 0 | 0 | 150.0 | 174 | 103 | 96 | 58 | 126 | 26 | 13 |
| Johan Santana* | ROK | sp | 28 | 3.33 | 15 | 13 | 0 | 33 | 33 | 1 | 1 | 219.0 | 183 | 88 | 81 | 52 | 235 | 33 | 14 |
| Victor Santos |   | mr | 30 | 5.83 | 1 | 6 | 0 | 36 | 3 | 0 | 0 | 63.1 | 71 | 41 | 41 | 33 | 48 | 15 | 9 |
| Dennis Sarfate |   | mr | 26 | 1.08 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 8.1 | 5 | 1 | 1 | 1 | 14 | 0 | 0 |
| Joe Saunders* | MID | sp | 26 | 4.44 | 8 | 5 | 0 | 18 | 18 | 0 | 0 | 107.1 | 129 | 56 | 53 | 34 | 69 | 11 | 10 |
| Curt Schilling | Pal | sp | 40 | 3.87 | 9 | 8 | 0 | 24 | 24 | 1 | 1 | 151.0 | 165 | 68 | 65 | 23 | 101 | 21 | 8 |
| Jason Schmidt |   | sp | 34 | 6.31 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 25.2 | 32 | 20 | 18 | 14 | 22 | 4 | 1 |
| Scott Schoeneweis* |   | mr | 33 | 5.03 | 0 | 2 | 2 | 70 | 0 | 0 | 0 | 59.0 | 62 | 36 | 33 | 28 | 41 | 8 | 6 |
| Chris Schroder | CCL | mr | 28 | 3.18 | 2 | 3 | 0 | 37 | 0 | 0 | 0 | 45.1 | 36 | 19 | 16 | 15 | 43 | 2 | 2 |
| Mike Schultz |   | mr | 27 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
| Rudy Seanez |   | mr | 38 | 3.79 | 6 | 3 | 1 | 73 | 0 | 0 | 0 | 76.0 | 78 | 33 | 32 | 27 | 73 | 10 | 7 |
| Bobby Seay* | ROK | mr | 29 | 2.33 | 3 | 0 | 1 | 58 | 0 | 0 | 0 | 46.1 | 38 | 12 | 12 | 15 | 38 | 1 | 3 |
| Chris Seddon* |   | sp | 23 | 8.83 | 0 | 2 | 0 | 7 | 4 | 0 | 0 | 17.1 | 29 | 19 | 17 | 5 | 10 | 2 | 0 |
| Zack Segovia |   | sp | 24 | 9.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.0 | 8 | 5 | 5 | 1 | 2 | 1 | 0 |
| Aaron Sele |   | mr | 37 | 5.37 | 3 | 2 | 0 | 34 | 0 | 0 | 0 | 53.2 | 78 | 34 | 32 | 21 | 29 | 5 | 10 |
| Jae Seo |   | sp | 30 | 8.13 | 3 | 4 | 0 | 11 | 10 | 0 | 0 | 52.0 | 84 | 53 | 47 | 16 | 28 | 11 | 5 |
| Dan Serafini* |   | mr | 33 | 54.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.1 | 0 | 2 | 2 | 2 | 0 | 0 | 0 |
| Josh Sharpless |   | mr | 26 | 12.46 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 4.1 | 7 | 6 | 6 | 1 | 1 | 3 | 0 |
| Tom Shearn |   | sp | 29 | 4.96 | 3 | 0 | 0 | 7 | 6 | 0 | 0 | 32.2 | 32 | 18 | 18 | 13 | 16 | 8 | 4 |
| Ben Sheets | TON | sp | 28 | 3.82 | 12 | 5 | 0 | 24 | 24 | 2 | 0 | 141.1 | 138 | 62 | 60 | 37 | 106 | 17 | 7 |
| George Sherrill* | ROK | mr | 30 | 2.36 | 2 | 0 | 3 | 73 | 0 | 0 | 0 | 45.2 | 28 | 12 | 12 | 17 | 56 | 4 | 1 |
| James Shields | BON | sp | 25 | 3.85 | 12 | 8 | 0 | 31 | 31 | 1 | 0 | 215.0 | 202 | 98 | 92 | 36 | 184 | 28 | 13 |
| Scot Shields | ROK | mr | 31 | 3.86 | 4 | 5 | 2 | 71 | 0 | 0 | 0 | 77.0 | 62 | 36 | 33 | 33 | 77 | 7 | 7 |
| Brian Shouse* | OTR | mr | 38 | 3.02 | 1 | 1 | 1 | 73 | 0 | 0 | 0 | 47.2 | 46 | 19 | 16 | 14 | 32 | 0 | 5 |
| Paul Shuey |   | mr | 36 | 9.82 | 0 | 1 | 1 | 25 | 0 | 0 | 0 | 25.2 | 33 | 28 | 28 | 21 | 22 | 3 | 5 |
| Carlos Silva | MID | sp | 28 | 4.19 | 13 | 14 | 0 | 33 | 33 | 2 | 1 | 202.0 | 229 | 99 | 94 | 36 | 89 | 20 | 24 |
| Jason Simontacchi |   | sp | 33 | 6.37 | 6 | 7 | 0 | 13 | 13 | 0 | 0 | 70.2 | 95 | 53 | 50 | 23 | 42 | 13 | 8 |
| Andrew Sisco* |   | mr | 24 | 8.36 | 0 | 1 | 0 | 19 | 0 | 0 | 0 | 14.0 | 19 | 13 | 13 | 11 | 13 | 2 | 0 |
| Doug Slaten* |   | mr | 27 | 2.72 | 3 | 2 | 0 | 61 | 0 | 0 | 0 | 36.1 | 41 | 15 | 11 | 14 | 28 | 4 | 4 |
| Kevin Slowey |   | sp | 23 | 4.72 | 4 | 1 | 0 | 13 | 11 | 0 | 0 | 66.2 | 82 | 39 | 35 | 11 | 47 | 16 | 2 |
| Joe Smith | LON | mr | 23 | 3.45 | 3 | 2 | 0 | 54 | 0 | 0 | 0 | 44.1 | 48 | 18 | 17 | 21 | 45 | 3 | 5 |
| Matt Smith* |   | mr | 28 | 11.25 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 4.0 | 4 | 5 | 5 | 11 | 1 | 0 | 0 |
| John Smoltz | WIZ | sp | 40 | 3.11 | 14 | 8 | 0 | 32 | 32 | 0 | 0 | 205.2 | 196 | 78 | 71 | 47 | 197 | 18 | 8 |
| Ian Snell |   | sp | 25 | 3.76 | 9 | 12 | 0 | 32 | 32 | 1 | 0 | 208.0 | 209 | 94 | 87 | 68 | 177 | 22 | 21 |
| Kyle Snyder |   | mr | 29 | 3.81 | 2 | 3 | 0 | 46 | 0 | 0 | 0 | 54.1 | 45 | 29 | 23 | 32 | 41 | 7 | 2 |
| Andy Sonnanstine |   | sp | 24 | 5.85 | 6 | 10 | 0 | 22 | 22 | 0 | 0 | 130.2 | 151 | 87 | 85 | 26 | 97 | 18 | 16 |
| Joakim Soria | BON | cl | 23 | 2.48 | 2 | 3 | 17 | 62 | 0 | 0 | 0 | 69.0 | 46 | 20 | 19 | 19 | 75 | 3 | 2 |
| Rafael Soriano | GEO | mr | 27 | 3.00 | 3 | 3 | 9 | 71 | 0 | 0 | 0 | 72.0 | 47 | 26 | 24 | 15 | 70 | 12 | 4 |
| Jorge Sosa |   | mr | 30 | 4.47 | 9 | 8 | 0 | 42 | 14 | 0 | 0 | 112.2 | 109 | 58 | 56 | 41 | 69 | 10 | 9 |
| Jeremy Sowers* |   | sp | 24 | 6.42 | 1 | 6 | 0 | 13 | 13 | 0 | 0 | 67.1 | 84 | 49 | 48 | 21 | 24 | 10 | 5 |
| Justin Speier | MID | mr | 33 | 2.88 | 2 | 3 | 0 | 51 | 0 | 0 | 0 | 50.0 | 36 | 17 | 16 | 12 | 47 | 6 | 0 |
| Ryan Speier |   | mr | 27 | 4.00 | 3 | 1 | 0 | 20 | 0 | 0 | 0 | 18.0 | 20 | 8 | 8 | 8 | 13 | 1 | 4 |
| Levale Speigner |   | mr | 26 | 8.77 | 2 | 3 | 0 | 19 | 6 | 0 | 0 | 40.0 | 58 | 39 | 39 | 23 | 19 | 4 | 4 |
| Russ Springer | WIZ | mr | 38 | 2.18 | 8 | 1 | 0 | 76 | 0 | 0 | 0 | 66.0 | 41 | 18 | 16 | 19 | 66 | 3 | 4 |
| Chris Spurling |   | mr | 30 | 4.68 | 2 | 1 | 0 | 49 | 0 | 0 | 0 | 50.0 | 63 | 31 | 26 | 14 | 28 | 6 | 5 |
| Jason Standridge |   | mr | 28 | 8.22 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 7.2 | 11 | 10 | 7 | 5 | 6 | 2 | 0 |
| Jason Stanford* |   | mr | 30 | 4.78 | 1 | 1 | 0 | 8 | 2 | 0 | 0 | 26.1 | 32 | 15 | 14 | 7 | 16 | 1 | 3 |
| Mike Stanton* |   | mr | 40 | 5.93 | 1 | 3 | 0 | 69 | 0 | 0 | 0 | 57.2 | 75 | 39 | 38 | 18 | 40 | 6 | 7 |
| Tim Stauffer | MAD | sp | 25 | 21.13 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 7.2 | 15 | 18 | 18 | 6 | 6 | 5 | 0 |
| Mitch Stetter* |   | mr | 26 | 3.60 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 5.0 | 2 | 2 | 2 | 2 | 4 | 0 | 1 |
| Brian Stokes |   | mr | 27 | 7.07 | 2 | 7 | 0 | 59 | 0 | 0 | 0 | 62.1 | 90 | 49 | 49 | 25 | 35 | 11 | 7 |
| Ricky Stone |   | mr | 32 | 10.13 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 5.1 | 7 | 6 | 6 | 0 | 3 | 4 | 1 |
| Huston Street | GEO | cl | 23 | 2.88 | 5 | 2 | 16 | 48 | 0 | 0 | 0 | 50.0 | 35 | 20 | 16 | 12 | 63 | 5 | 0 |
| Eric Stults* |   | mr | 27 | 5.82 | 1 | 4 | 0 | 12 | 5 | 0 | 0 | 38.2 | 50 | 26 | 25 | 17 | 30 | 5 | 4 |
| Jeff Suppan |   | sp | 32 | 4.62 | 12 | 12 | 0 | 34 | 34 | 1 | 0 | 206.2 | 243 | 113 | 106 | 68 | 114 | 18 | 23 |
| Jon Switzer* |   | mr | 27 | 8.05 | 0 | 2 | 0 | 21 | 0 | 0 | 0 | 19.0 | 27 | 17 | 17 | 7 | 13 | 2 | 2 |
| Brian Tallet* | EDG | mr | 29 | 3.47 | 2 | 4 | 0 | 48 | 0 | 0 | 0 | 62.1 | 49 | 26 | 24 | 28 | 54 | 1 | 4 |
| Taylor Tankersley* |   | mr | 24 | 3.99 | 6 | 1 | 1 | 67 | 0 | 0 | 0 | 47.1 | 42 | 22 | 21 | 29 | 49 | 4 | 5 |
| Jack Taschner* |   | mr | 29 | 5.40 | 3 | 1 | 0 | 63 | 0 | 0 | 0 | 50.0 | 44 | 31 | 30 | 29 | 51 | 4 | 2 |
| Jordan Tata |   | sp | 25 | 7.71 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 14.0 | 16 | 12 | 12 | 8 | 8 | 1 | 3 |
| Ty Taubenheim |   | sp | 24 | 9.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 5 | 5 | 5 | 4 | 4 | 1 | 0 |
| Julian Tavarez |   | sp | 34 | 5.15 | 7 | 11 | 0 | 34 | 23 | 0 | 0 | 134.2 | 151 | 89 | 77 | 51 | 77 | 14 | 17 |
| Robinson Tejeda |   | sp | 25 | 6.61 | 5 | 9 | 0 | 19 | 19 | 0 | 0 | 95.1 | 110 | 78 | 70 | 60 | 69 | 17 | 5 |
| Joe Thatcher* |   | mr | 25 | 1.29 | 2 | 2 | 0 | 22 | 0 | 0 | 0 | 21.0 | 13 | 6 | 3 | 6 | 16 | 1 | 1 |
| Brad Thompson |   | mr | 25 | 4.73 | 8 | 6 | 0 | 44 | 17 | 0 | 0 | 129.1 | 157 | 76 | 68 | 40 | 53 | 23 | 19 |
| Mike Thompson |   | mr | 26 | 6.89 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 15.2 | 19 | 15 | 12 | 7 | 5 | 2 | 3 |
| Rich Thompson |   | mr | 22 | 10.80 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 6.2 | 10 | 8 | 8 | 3 | 9 | 4 | 0 |
| John Thomson |   | sp | 33 | 3.38 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 10.2 | 13 | 5 | 4 | 3 | 3 | 0 | 2 |
| Matt Thornton* | CRH | mr | 30 | 4.79 | 4 | 4 | 2 | 68 | 0 | 0 | 0 | 56.1 | 59 | 31 | 30 | 26 | 55 | 4 | 7 |
| Erick Threets* |   | mr | 25 | 19.29 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.1 | 5 | 5 | 5 | 3 | 1 | 0 | 0 |
| Mike Timlin | OTR | mr | 41 | 3.42 | 2 | 1 | 1 | 50 | 0 | 0 | 0 | 55.1 | 46 | 23 | 21 | 14 | 31 | 7 | 7 |
| Brett Tomko |   | mr | 34 | 5.55 | 4 | 12 | 0 | 40 | 19 | 0 | 0 | 131.1 | 149 | 89 | 81 | 48 | 105 | 18 | 10 |
| Salomon Torres |   | mr | 35 | 5.47 | 2 | 4 | 12 | 56 | 0 | 0 | 0 | 52.2 | 57 | 34 | 32 | 17 | 45 | 7 | 7 |
| Josh Towers |   | sp | 30 | 5.38 | 5 | 10 | 0 | 25 | 15 | 0 | 0 | 107.0 | 129 | 73 | 64 | 22 | 76 | 18 | 9 |
| Billy Traber* |   | mr | 27 | 4.76 | 2 | 2 | 0 | 28 | 2 | 0 | 0 | 39.2 | 50 | 22 | 21 | 13 | 27 | 4 | 3 |
| Steve Trachsel |   | sp | 36 | 4.90 | 7 | 11 | 0 | 29 | 29 | 1 | 0 | 158.0 | 176 | 89 | 86 | 76 | 56 | 19 | 13 |
| Chin-hui Tsao |   | mr | 26 | 4.38 | 0 | 1 | 0 | 21 | 0 | 0 | 0 | 24.2 | 18 | 12 | 12 | 8 | 16 | 3 | 2 |
| Derrick Turnbow | MAD | mr | 29 | 4.63 | 4 | 5 | 1 | 77 | 0 | 0 | 0 | 68.0 | 44 | 36 | 35 | 46 | 84 | 4 | 6 |
| Lino Urdaneta |   | mr | 27 | 9.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.0 | 2 | 1 | 1 | 0 | 0 | 1 | 0 |
| Jose Valverde | WIZ | cl | 27 | 2.66 | 1 | 4 | 47 | 65 | 0 | 0 | 0 | 64.1 | 46 | 21 | 19 | 26 | 78 | 7 | 5 |
| John Van Benschoten |   | sp | 27 | 10.15 | 0 | 7 | 0 | 11 | 9 | 0 | 0 | 39.0 | 55 | 45 | 44 | 29 | 26 | 4 | 1 |
| Rick VandenHurk |   | sp | 22 | 6.83 | 4 | 6 | 0 | 18 | 17 | 0 | 0 | 81.2 | 94 | 63 | 62 | 48 | 82 | 15 | 5 |
| Claudio Vargas |   | sp | 29 | 5.09 | 11 | 6 | 1 | 29 | 23 | 0 | 0 | 134.1 | 153 | 80 | 76 | 54 | 107 | 23 | 6 |
| Jason Vargas* |   | sp | 24 | 12.19 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 10.1 | 17 | 14 | 14 | 2 | 4 | 4 | 0 |
| Virgil Vasquez |   | sp | 25 | 8.64 | 0 | 1 | 0 | 5 | 3 | 0 | 0 | 16.2 | 27 | 16 | 16 | 5 | 7 | 7 | 1 |
| Javier Vazquez | Pal | sp | 30 | 3.74 | 15 | 8 | 0 | 32 | 32 | 2 | 0 | 216.2 | 197 | 95 | 90 | 50 | 213 | 29 | 13 |
| Jose Veras |   | mr | 26 | 5.79 | 0 | 0 | 2 | 9 | 0 | 0 | 0 | 9.1 | 6 | 6 | 6 | 7 | 7 | 0 | 0 |
| Justin Verlander | COP | sp | 24 | 3.66 | 18 | 6 | 0 | 32 | 32 | 1 | 1 | 201.2 | 181 | 88 | 82 | 67 | 183 | 20 | 10 |
| Jamie Vermilyea |   | mr | 25 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 0 | 2 | 0 | 1 |
| Carlos Villanueva | TON | mr | 23 | 3.94 | 8 | 5 | 1 | 59 | 6 | 0 | 0 | 114.1 | 101 | 52 | 50 | 53 | 99 | 16 | 11 |
| Oscar Villarreal |   | mr | 25 | 4.24 | 2 | 2 | 1 | 51 | 0 | 0 | 0 | 76.1 | 75 | 40 | 36 | 32 | 58 | 6 | 4 |
| Ron Villone* |   | mr | 37 | 4.25 | 0 | 0 | 0 | 37 | 0 | 0 | 0 | 42.1 | 36 | 20 | 20 | 18 | 25 | 5 | 8 |
| Luis Vizcaino | LON | mr | 32 | 4.30 | 8 | 2 | 0 | 77 | 0 | 0 | 0 | 75.1 | 66 | 37 | 36 | 43 | 62 | 6 | 4 |
| Edinson Volquez |   | sp | 23 | 4.50 | 2 | 1 | 0 | 6 | 6 | 0 | 0 | 34.0 | 34 | 18 | 17 | 15 | 29 | 4 | 4 |
| Billy Wagner* | BT | cl | 35 | 2.63 | 2 | 2 | 34 | 66 | 0 | 0 | 0 | 68.1 | 55 | 22 | 20 | 22 | 80 | 6 | 6 |
| Ryan Wagner |   | mr | 24 | 5.74 | 0 | 2 | 0 | 14 | 0 | 0 | 0 | 15.2 | 20 | 11 | 10 | 8 | 9 | 2 | 2 |
| Adam Wainwright | MAD | sp | 25 | 3.70 | 14 | 12 | 0 | 32 | 32 | 1 | 0 | 202.0 | 212 | 93 | 83 | 70 | 136 | 13 | 19 |
| Tim Wakefield | OTR | sp | 40 | 4.76 | 17 | 12 | 0 | 31 | 31 | 0 | 0 | 189.0 | 191 | 104 | 100 | 64 | 110 | 22 | 14 |
| Jamie Walker* | OTR | mr | 35 | 3.23 | 3 | 2 | 7 | 81 | 0 | 0 | 0 | 61.1 | 57 | 25 | 22 | 17 | 41 | 6 | 4 |
| Tyler Walker |   | mr | 31 | 1.26 | 2 | 0 | 0 | 15 | 0 | 0 | 0 | 14.1 | 12 | 2 | 2 | 4 | 9 | 0 | 4 |
| Chien-Ming Wang | MID | sp | 27 | 3.70 | 19 | 7 | 0 | 30 | 30 | 1 | 0 | 199.1 | 199 | 84 | 82 | 59 | 104 | 9 | 32 |
| John Wasdin |   | mr | 34 | 5.95 | 1 | 1 | 0 | 12 | 0 | 0 | 0 | 19.2 | 32 | 13 | 13 | 8 | 10 | 1 | 3 |
| Jarrod Washburn* |   | sp | 32 | 4.32 | 10 | 15 | 0 | 32 | 32 | 1 | 1 | 193.2 | 201 | 102 | 93 | 67 | 114 | 23 | 17 |
| Ehren Wassermann |   | mr | 26 | 2.74 | 1 | 1 | 0 | 33 | 0 | 0 | 0 | 23.0 | 20 | 9 | 7 | 7 | 14 | 0 | 4 |
| David Weathers | TON | cl | 37 | 3.59 | 2 | 6 | 33 | 70 | 0 | 0 | 0 | 77.2 | 67 | 33 | 31 | 27 | 48 | 4 | 5 |
| Jeff Weaver |   | sp | 30 | 6.20 | 7 | 13 | 0 | 27 | 27 | 3 | 2 | 146.2 | 190 | 105 | 101 | 35 | 80 | 23 | 13 |
| Jered Weaver | OTR | sp | 24 | 3.91 | 13 | 7 | 0 | 28 | 28 | 0 | 0 | 161.0 | 178 | 77 | 70 | 45 | 115 | 17 | 10 |
| Brandon Webb | TON | sp | 28 | 3.01 | 18 | 10 | 0 | 34 | 34 | 4 | 3 | 236.1 | 209 | 91 | 79 | 72 | 194 | 12 | 20 |
| Todd Wellemeyer |   | mr | 28 | 4.54 | 3 | 3 | 0 | 32 | 11 | 0 | 0 | 79.1 | 77 | 50 | 40 | 40 | 60 | 11 | 11 |
| David Wells* |   | sp | 44 | 5.43 | 9 | 9 | 0 | 29 | 29 | 0 | 0 | 157.1 | 201 | 97 | 95 | 42 | 82 | 22 | 12 |
| Kip Wells |   | sp | 30 | 5.70 | 7 | 17 | 0 | 34 | 26 | 0 | 0 | 162.2 | 186 | 116 | 103 | 78 | 122 | 19 | 12 |
| Jake Westbrook | MID | sp | 29 | 4.32 | 6 | 9 | 0 | 25 | 25 | 0 | 0 | 152.0 | 159 | 78 | 73 | 55 | 93 | 13 | 20 |
| Dan Wheeler | Pal | mr | 29 | 5.30 | 1 | 9 | 11 | 70 | 0 | 0 | 0 | 74.2 | 74 | 48 | 44 | 23 | 82 | 11 | 5 |
| Bill White* |   | mr | 28 | 4.82 | 2 | 0 | 0 | 9 | 0 | 0 | 0 | 9.1 | 8 | 5 | 5 | 7 | 9 | 1 | 2 |
| Rick White |   | mr | 38 | 7.79 | 1 | 1 | 0 | 29 | 0 | 0 | 0 | 34.2 | 47 | 31 | 30 | 18 | 18 | 4 | 3 |
| Sean White |   | mr | 26 | 5.60 | 1 | 1 | 0 | 15 | 0 | 0 | 0 | 35.1 | 35 | 24 | 22 | 20 | 16 | 2 | 5 |
| Bob Wickman |   | cl | 38 | 3.58 | 3 | 4 | 20 | 57 | 0 | 0 | 0 | 50.1 | 54 | 24 | 20 | 21 | 37 | 4 | 2 |
| Dave Williams* |   | sp | 28 | 22.85 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 4.1 | 12 | 11 | 11 | 5 | 2 | 2 | 1 |
| Jerome Williams |   | sp | 25 | 7.20 | 0 | 5 | 0 | 6 | 6 | 0 | 0 | 30.0 | 34 | 26 | 24 | 18 | 15 | 6 | 4 |
| Todd Williams |   | mr | 36 | 7.53 | 0 | 2 | 0 | 14 | 0 | 0 | 0 | 14.1 | 19 | 12 | 12 | 4 | 9 | 2 | 2 |
| Woody Williams |   | sp | 40 | 5.27 | 8 | 15 | 0 | 33 | 31 | 0 | 0 | 188.0 | 216 | 114 | 110 | 53 | 101 | 35 | 9 |
| Scott Williamson |   | mr | 31 | 4.40 | 1 | 0 | 0 | 16 | 0 | 0 | 0 | 14.1 | 12 | 8 | 7 | 8 | 16 | 1 | 0 |
| Dontrelle Willis* |   | sp | 25 | 5.17 | 10 | 15 | 0 | 35 | 35 | 0 | 0 | 205.1 | 241 | 131 | 118 | 87 | 146 | 29 | 18 |
| Brian Wilson |   | cl | 25 | 2.28 | 1 | 2 | 6 | 24 | 0 | 0 | 0 | 23.2 | 16 | 6 | 6 | 7 | 18 | 1 | 1 |
| C.J. Wilson* | ROK | mr | 26 | 3.03 | 2 | 1 | 12 | 66 | 0 | 0 | 0 | 68.1 | 50 | 25 | 23 | 33 | 63 | 4 | 12 |
| Matt Wise |   | mr | 31 | 4.19 | 3 | 2 | 1 | 56 | 0 | 0 | 0 | 53.2 | 61 | 30 | 25 | 17 | 43 | 5 | 6 |
| Jay Witasick |   | mr | 34 | 5.17 | 1 | 0 | 0 | 36 | 0 | 0 | 0 | 31.1 | 31 | 19 | 18 | 27 | 18 | 2 | 5 |
| Randy Wolf* | CCL | sp | 30 | 4.73 | 9 | 6 | 0 | 18 | 18 | 0 | 0 | 102.2 | 110 | 55 | 54 | 39 | 94 | 10 | 6 |
| Ross Wolf |   | mr | 24 | 11.68 | 0 | 1 | 0 | 14 | 0 | 0 | 0 | 12.1 | 24 | 16 | 16 | 3 | 6 | 4 | 0 |
| Brian Wolfe | OTR | mr | 26 | 2.98 | 3 | 1 | 0 | 38 | 0 | 0 | 0 | 45.1 | 36 | 17 | 15 | 9 | 22 | 5 | 5 |
| Kerry Wood | MUL | mr | 30 | 3.33 | 1 | 1 | 0 | 22 | 0 | 0 | 0 | 24.1 | 18 | 9 | 9 | 13 | 24 | 0 | 2 |
| Mike Wood |   | mr | 27 | 5.33 | 3 | 2 | 0 | 21 | 4 | 0 | 0 | 50.2 | 68 | 36 | 30 | 15 | 25 | 9 | 5 |
| Jake Woods* |   | mr | 25 | 5.91 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 10.2 | 9 | 8 | 7 | 7 | 4 | 1 | 1 |
| Chase Wright* |   | sp | 24 | 7.20 | 2 | 0 | 0 | 3 | 2 | 0 | 0 | 10.0 | 12 | 8 | 8 | 6 | 8 | 5 | 1 |
| Jamey Wright |   | mr | 32 | 3.62 | 4 | 5 | 0 | 20 | 9 | 0 | 0 | 77.0 | 72 | 35 | 31 | 41 | 39 | 6 | 15 |
| Jaret Wright |   | sp | 31 | 6.97 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 10.1 | 12 | 11 | 8 | 9 | 7 | 1 | 1 |
| Michael Wuertz | BT | mr | 28 | 3.48 | 2 | 3 | 0 | 73 | 0 | 0 | 0 | 72.1 | 64 | 30 | 28 | 35 | 79 | 8 | 4 |
| Tyler Yates |   | mr | 29 | 5.18 | 2 | 3 | 2 | 75 | 0 | 0 | 0 | 66.0 | 64 | 44 | 38 | 31 | 69 | 6 | 1 |
| Shane Youman* |   | sp | 27 | 5.97 | 3 | 5 | 0 | 16 | 8 | 0 | 0 | 57.1 | 65 | 40 | 38 | 23 | 29 | 5 | 5 |
| Chris Young | COP | sp | 28 | 3.12 | 9 | 8 | 0 | 30 | 30 | 0 | 0 | 173.0 | 118 | 66 | 60 | 72 | 167 | 10 | 9 |
| Mike Zagurski* |   | mr | 24 | 5.91 | 1 | 0 | 0 | 25 | 0 | 0 | 0 | 21.1 | 25 | 14 | 14 | 11 | 21 | 3 | 2 |
| Carlos Zambrano | CCL | sp | 26 | 3.95 | 18 | 13 | 0 | 34 | 34 | 1 | 0 | 216.1 | 187 | 100 | 95 | 101 | 177 | 23 | 19 |
| Victor Zambrano |   | mr | 31 | 10.17 | 0 | 3 | 0 | 13 | 4 | 0 | 0 | 23.0 | 32 | 26 | 26 | 22 | 16 | 6 | 2 |
| Mauro Zarate |   | mr | 24 | 10.80 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.0 | 11 | 7 | 6 | 1 | 3 | 3 | 0 |
| Barry Zito* | EDG | sp | 29 | 4.53 | 11 | 13 | 0 | 34 | 33 | 0 | 0 | 196.2 | 182 | 105 | 99 | 83 | 131 | 24 | 15 |
| Joel Zumaya |   | mr | 22 | 4.28 | 2 | 3 | 1 | 28 | 0 | 0 | 0 | 33.2 | 23 | 16 | 16 | 17 | 27 | 3 | 2 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | CI | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | BT | mr | 25 | 0 | 0 | 3 | 1 | 2 | 0 | 2 | 1 | 0 | 10.9 | 4.7 | 15.9 | 10.0 | 1.1 | 2.1 | 1.73 |
| Winston Abreu |   | mr | 30 | 4 | 0 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 11.0 | 2.7 | 13.6 | 7.7 | 2.1 | 2.9 | 1.52 |
| Jeremy Accardo | CRH | cl | 25 | 10 | 1 | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 6.8 | 3.2 | 10.3 | 7.6 | 0.5 | 2.4 | 1.11 |
| Manny Acosta |   | mr | 26 | 4 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 4.9 | 5.3 | 10.3 | 8.4 | 0.8 | 1.6 | 1.14 |
| Jon Adkins |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.00 |
| Jeremy Affeldt* | CRH | mr | 28 | 7 | 1 | 9 | 3 | 6 | 1 | 3 | 6 | 0 | 7.2 | 5.0 | 12.7 | 7.0 | 0.5 | 1.4 | 1.36 |
| Jonathan Albaladejo |   | mr | 24 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.4 | 1.3 | 6.3 | 7.5 | 0.6 | 6.0 | 0.63 |
| Matt Albers |   | sp | 24 | 11 | 3 | 6 | 7 | 7 | 0 | 6 | 8 | 0 | 10.3 | 4.1 | 15.0 | 5.8 | 1.5 | 1.4 | 1.60 |
| Antonio Alfonseca |   | mr | 35 | 7 | 0 | 6 | 1 | 1 | 0 | 0 | 1 | 0 | 11.8 | 4.9 | 16.9 | 4.3 | 0.5 | 0.9 | 1.85 |
| Greg Aquino |   | mr | 29 | 0 | 0 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 8.4 | 3.2 | 11.6 | 7.7 | 1.3 | 2.4 | 1.29 |
| Alberto Arias |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.8 | 6.1 | 16.0 | 3.7 | 1.2 | 0.6 | 1.77 |
| Tony Armas |   | mr | 29 | 11 | 2 | 3 | 8 | 2 | 0 | 2 | 7 | 0 | 10.3 | 3.5 | 14.6 | 6.8 | 1.7 | 1.9 | 1.54 |
| Bronson Arroyo | BT | sp | 30 | 3 | 6 | 6 | 13 | 4 | 0 | 10 | 7 | 0 | 9.9 | 2.7 | 13.2 | 6.7 | 1.2 | 2.5 | 1.40 |
| Jose Ascanio |   | mr | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 9.6 | 3.4 | 12.9 | 7.3 | 1.7 | 2.2 | 1.44 |
| Scott Atchison |   | mr | 31 | 4 | 0 | 0 | 1 | 2 | 0 | 1 | 2 | 0 | 9.4 | 2.9 | 12.6 | 7.3 | 1.5 | 2.5 | 1.37 |
| Luis Ayala |   | mr | 29 | 1 | 1 | 0 | 1 | 1 | 0 | 3 | 4 | 0 | 9.1 | 2.6 | 11.9 | 6.0 | 1.1 | 2.3 | 1.30 |
| Brandon Backe |   | sp | 29 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 8.5 | 3.5 | 12.6 | 3.5 | 1.3 | 1.0 | 1.33 |
| Mike Bacsik* |   | sp | 29 | 2 | 2 | 3 | 6 | 4 | 0 | 3 | 4 | 0 | 10.8 | 2.2 | 13.4 | 3.4 | 2.0 | 1.6 | 1.44 |
| Cha Seung Baek | EDG | sp | 27 | 1 | 2 | 1 | 3 | 1 | 0 | 1 | 1 | 0 | 10.7 | 1.7 | 12.8 | 6.0 | 0.7 | 3.5 | 1.38 |
| Danys Baez |   | mr | 29 | 6 | 0 | 5 | 7 | 0 | 0 | 3 | 1 | 0 | 8.9 | 5.2 | 15.4 | 5.2 | 1.4 | 1.0 | 1.57 |
| Homer Bailey | CCL | sp | 21 | 9 | 0 | 1 | 3 | 1 | 1 | 1 | 6 | 0 | 8.5 | 5.6 | 14.7 | 5.6 | 0.6 | 1.0 | 1.57 |
| Scott Baker | BON | sp | 25 | 11 | 4 | 4 | 5 | 0 | 0 | 6 | 2 | 0 | 10.1 | 1.8 | 12.3 | 6.4 | 0.9 | 3.5 | 1.33 |
| John Bale* | BON | mr | 33 | 0 | 0 | 2 | 1 | 2 | 0 | 3 | 3 | 0 | 10.1 | 3.8 | 14.2 | 9.4 | 0.2 | 2.5 | 1.55 |
| Grant Balfour |   | mr | 29 | 3 | 1 | 0 | 1 | 0 | 0 | 2 | 3 | 0 | 10.9 | 7.3 | 18.6 | 10.9 | 0.7 | 1.5 | 2.03 |
| Josh Banks |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 13.5 | 2.5 | 16.0 | 2.5 | 1.2 | 1.0 | 1.77 |
| Brian Bannister | EDG | sp | 26 | 7 | 5 | 1 | 6 | 4 | 0 | 2 | 4 | 1 | 8.5 | 2.4 | 11.2 | 4.2 | 0.8 | 1.8 | 1.21 |
| Daniel Barone |   | mr | 24 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 2 | 0 | 11.0 | 4.2 | 15.4 | 4.0 | 2.4 | 0.9 | 1.68 |
| Kevin Barry |   | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 27.0 | 9.0 | 36.0 | 18.0 | 0.0 | 2.0 | 4.00 |
| Miguel Batista |   | sp | 36 | 14 | 9 | 3 | 8 | 15 | 2 | 5 | 5 | 0 | 9.7 | 4.0 | 14.1 | 6.2 | 0.8 | 1.6 | 1.52 |
| Denny Bautista |   | mr | 26 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 18.7 | 4.2 | 23.9 | 8.3 | 0.0 | 2.0 | 2.54 |
| Jonah Bayliss |   | mr | 26 | 4 | 1 | 2 | 2 | 1 | 0 | 0 | 1 | 0 | 12.2 | 4.3 | 17.0 | 6.9 | 1.9 | 1.6 | 1.83 |
| Yorman Bazardo |   | mr | 22 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 7.2 | 1.9 | 10.3 | 5.7 | 0.8 | 3.0 | 1.01 |
| Colter Bean |   | mr | 30 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 15.0 | 30.0 | 6.0 | 0.0 | 0.4 | 3.33 |
| Josh Beckett | Pal | sp | 27 | 14 | 6 | 0 | 5 | 3 | 0 | 3 | 2 | 0 | 8.5 | 1.8 | 10.5 | 8.7 | 0.8 | 4.8 | 1.14 |
| Erik Bedard* | GEO | sp | 28 | 5 | 2 | 0 | 5 | 3 | 0 | 2 | 4 | 0 | 7.0 | 2.8 | 10.0 | 10.9 | 0.9 | 3.9 | 1.09 |
| Joe Beimel* | WIZ | mr | 30 | 2 | 3 | 6 | 1 | 3 | 2 | 5 | 2 | 0 | 8.4 | 3.2 | 11.8 | 5.2 | 0.1 | 1.6 | 1.29 |
| Matt Belisle | CCL | sp | 27 | 11 | 6 | 4 | 7 | 6 | 1 | 7 | 9 | 0 | 10.7 | 2.2 | 13.3 | 6.3 | 1.3 | 2.9 | 1.44 |
| Heath Bell | MUL | mr | 29 | 8 | 3 | 1 | 2 | 4 | 0 | 4 | 1 | 1 | 5.8 | 2.9 | 8.8 | 9.8 | 0.3 | 3.4 | 0.96 |
| Rob Bell |   | mr | 30 | 9 | 1 | 5 | 0 | 2 | 0 | 1 | 3 | 0 | 12.4 | 4.1 | 16.5 | 4.8 | 1.2 | 1.2 | 1.83 |
| Armando Benitez |   | mr | 34 | 6 | 0 | 2 | 1 | 1 | 3 | 6 | 1 | 0 | 8.8 | 5.2 | 14.1 | 10.2 | 1.4 | 2.0 | 1.55 |
| Jeff Bennett |   | sp | 27 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 9.7 | 2.1 | 11.8 | 9.7 | 2.1 | 4.7 | 1.31 |
| Joaquin Benoit | OTR | mr | 29 | 2 | 2 | 2 | 2 | 3 | 0 | 3 | 2 | 0 | 7.5 | 3.1 | 10.8 | 9.5 | 0.7 | 3.1 | 1.17 |
| Jason Bergmann |   | sp | 25 | 8 | 3 | 1 | 2 | 4 | 0 | 6 | 1 | 0 | 7.7 | 3.3 | 11.2 | 6.7 | 1.4 | 2.0 | 1.22 |
| Rafael Betancourt | GEO | mr | 32 | 4 | 4 | 3 | 0 | 0 | 0 | 0 | 2 | 0 | 5.8 | 1.0 | 6.8 | 9.1 | 0.5 | 8.9 | 0.76 |
| Chad Billingsley | TON | mr | 22 | 5 | 6 | 3 | 3 | 5 | 0 | 9 | 3 | 0 | 8.0 | 3.9 | 12.1 | 8.6 | 0.9 | 2.2 | 1.33 |
| Kurt Birkins* |   | mr | 26 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 13.6 | 3.7 | 18.1 | 7.9 | 0.8 | 2.1 | 1.92 |
| Joe Bisenius |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 13.5 | 0.0 | 1.5 | 2.00 |
| Nick Blackburn |   | mr | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.7 | 1.5 | 16.2 | 6.2 | 1.5 | 4.0 | 1.80 |
| Travis Blackley* |   | sp | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 10.4 | 5.2 | 15.6 | 5.2 | 2.1 | 1.0 | 1.73 |
| Joe Blanton | BON | sp | 26 | 19 | 4 | 4 | 4 | 3 | 1 | 5 | 8 | 0 | 9.4 | 1.6 | 11.1 | 5.5 | 0.6 | 3.5 | 1.22 |
| Jerry Blevins* |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.4 | 3.9 | 19.3 | 5.8 | 1.9 | 1.5 | 2.14 |
| Jeremy Bonderman |   | sp | 24 | 19 | 4 | 6 | 4 | 12 | 1 | 2 | 4 | 0 | 10.0 | 2.5 | 12.6 | 7.5 | 1.2 | 3.0 | 1.38 |
| Boof Bonser |   | sp | 25 | 11 | 7 | 4 | 5 | 3 | 1 | 4 | 3 | 0 | 10.4 | 3.4 | 14.0 | 7.1 | 1.4 | 2.1 | 1.53 |
| Chris Booker |   | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 9.0 | 9.0 | 18.0 | 9.0 | 9.0 | 1.0 | 2.00 |
| Chris Bootcheck |   | mr | 28 | 6 | 2 | 3 | 5 | 6 | 1 | 2 | 4 | 0 | 9.4 | 2.8 | 12.8 | 6.5 | 0.8 | 2.3 | 1.36 |
| Dave Borkowski |   | mr | 30 | 2 | 0 | 9 | 4 | 3 | 0 | 3 | 6 | 0 | 9.5 | 4.3 | 14.3 | 7.9 | 1.0 | 1.9 | 1.53 |
| Joe Borowski | EDG | cl | 36 | 9 | 2 | 4 | 2 | 2 | 0 | 3 | 4 | 0 | 10.6 | 2.3 | 13.2 | 7.9 | 1.2 | 3.4 | 1.43 |
| Micah Bowie* |   | mr | 32 | 3 | 2 | 0 | 2 | 0 | 0 | 4 | 4 | 0 | 8.6 | 4.2 | 13.2 | 6.6 | 1.1 | 1.6 | 1.43 |
| Blaine Boyer |   | mr | 25 | 1 | 0 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 16.9 | 1.7 | 18.6 | 5.1 | 0.0 | 3.0 | 2.06 |
| Dallas Braden* |   | sp | 23 | 2 | 1 | 1 | 2 | 6 | 1 | 4 | 0 | 0 | 11.3 | 3.2 | 14.8 | 6.8 | 1.1 | 2.1 | 1.62 |
| Chad Bradford | MID | mr | 32 | 4 | 1 | 3 | 6 | 0 | 0 | 4 | 1 | 0 | 10.7 | 2.2 | 13.8 | 4.0 | 0.1 | 1.8 | 1.44 |
| Ryan Braun |   | mr | 26 | 3 | 1 | 1 | 0 | 3 | 0 | 2 | 5 | 0 | 10.5 | 5.0 | 15.6 | 5.5 | 0.9 | 1.1 | 1.73 |
| Bill Bray* |   | mr | 24 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 10.0 | 3.1 | 13.2 | 8.8 | 0.6 | 2.8 | 1.47 |
| Yhency Brazoban |   | mr | 27 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 16.2 | 16.2 | 32.4 | 27.0 | 0.0 | 1.7 | 3.60 |
| Chris Britton |   | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 6.4 | 2.8 | 9.2 | 3.6 | 1.4 | 1.3 | 1.03 |
| Lance Broadway |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.4 | 4.4 | 8.7 | 12.2 | 0.0 | 2.8 | 0.97 |
| Doug Brocail | CCL | mr | 40 | 3 | 0 | 3 | 2 | 2 | 0 | 2 | 1 | 0 | 7.7 | 2.8 | 10.8 | 5.0 | 0.9 | 1.8 | 1.17 |
| Jim Brower |   | mr | 34 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 21.6 | 5.4 | 29.7 | 2.7 | 0.0 | 0.5 | 3.00 |
| Andrew Brown | EDG | mr | 26 | 3 | 0 | 3 | 3 | 6 | 0 | 2 | 1 | 0 | 8.2 | 3.7 | 12.5 | 9.3 | 0.2 | 2.5 | 1.32 |
| Jonathan Broxton | CCL | mr | 23 | 6 | 3 | 3 | 1 | 4 | 0 | 0 | 1 | 0 | 7.6 | 2.7 | 10.4 | 10.9 | 0.7 | 4.0 | 1.15 |
| Brian Bruney |   | mr | 25 | 4 | 5 | 2 | 3 | 4 | 0 | 1 | 6 | 0 | 7.9 | 6.7 | 15.1 | 7.0 | 0.9 | 1.1 | 1.62 |
| Clay Buchholz |   | sp | 22 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.6 | 4.0 | 9.9 | 8.7 | 0.0 | 2.2 | 1.06 |
| Taylor Buchholz | TON | mr | 25 | 7 | 0 | 4 | 2 | 3 | 1 | 5 | 5 | 0 | 10.1 | 1.9 | 12.2 | 5.9 | 0.8 | 3.0 | 1.33 |
| Billy Buckner |   | sp | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.8 | 4.2 | 14.0 | 4.5 | 1.3 | 1.1 | 1.56 |
| Mark Buehrle* | GEO | sp | 28 | 2 | 3 | 5 | 5 | 1 | 0 | 7 | 5 | 0 | 9.3 | 2.0 | 11.6 | 5.1 | 1.0 | 2.6 | 1.26 |
| Ryan Bukvich |   | mr | 29 | 1 | 0 | 1 | 3 | 3 | 0 | 1 | 2 | 0 | 9.1 | 6.1 | 15.9 | 4.5 | 1.3 | 0.8 | 1.68 |
| Jason Bulger |   | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.1 | 4.3 | 11.4 | 11.4 | 0.0 | 2.7 | 1.26 |
| Bryan Bullington |   | sp | 26 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 12.7 | 2.6 | 15.4 | 3.7 | 1.6 | 1.4 | 1.71 |
| Ambiorix Burgos |   | mr | 23 | 1 | 0 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 6.5 | 3.4 | 10.6 | 7.2 | 1.1 | 2.1 | 1.10 |
| A.J. Burnett | TON | sp | 30 | 31 | 0 | 2 | 12 | 5 | 0 | 0 | 2 | 0 | 7.1 | 3.6 | 11.4 | 9.6 | 1.2 | 2.7 | 1.19 |
| Brian Burres* |   | mr | 26 | 11 | 5 | 1 | 5 | 8 | 0 | 2 | 0 | 0 | 10.4 | 4.9 | 15.7 | 7.1 | 1.0 | 1.5 | 1.70 |
| Jared Burton | MAD | mr | 26 | 4 | 1 | 4 | 2 | 3 | 1 | 1 | 1 | 0 | 5.9 | 4.6 | 10.9 | 7.5 | 0.4 | 1.6 | 1.16 |
| Dave Bush | OTR | sp | 27 | 15 | 7 | 1 | 11 | 3 | 0 | 6 | 2 | 0 | 10.5 | 2.1 | 13.1 | 6.5 | 1.3 | 3.0 | 1.40 |
| Paul Byrd |   | sp | 36 | 11 | 2 | 3 | 6 | 5 | 0 | 4 | 4 | 0 | 11.2 | 1.3 | 12.8 | 4.1 | 1.3 | 3.1 | 1.39 |
| Tim Byrdak* | EDG | mr | 33 | 2 | 1 | 4 | 1 | 3 | 0 | 2 | 5 | 0 | 7.6 | 5.2 | 13.0 | 9.8 | 0.6 | 1.9 | 1.42 |
| Daniel Cabrera |   | sp | 26 | 24 | 4 | 6 | 15 | 7 | 2 | 13 | 5 | 0 | 9.1 | 4.8 | 14.5 | 7.3 | 1.1 | 1.5 | 1.54 |
| Fernando Cabrera |   | mr | 25 | 4 | 4 | 3 | 0 | 2 | 0 | 0 | 2 | 0 | 10.3 | 6.4 | 16.7 | 9.9 | 1.9 | 1.5 | 1.85 |
| Matt Cain | LON | sp | 22 | 8 | 5 | 3 | 5 | 12 | 0 | 8 | 5 | 0 | 7.8 | 3.6 | 11.6 | 7.3 | 0.6 | 2.1 | 1.26 |
| Kiko Calero |   | mr | 32 | 8 | 0 | 2 | 2 | 1 | 0 | 0 | 5 | 0 | 10.2 | 4.6 | 15.3 | 6.9 | 0.7 | 1.5 | 1.65 |
| Carmen Cali* |   | mr | 28 | 0 | 0 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 9.4 | 6.9 | 17.1 | 6.0 | 0.9 | 0.9 | 1.81 |
| Kevin Cameron | LON | mr | 27 | 9 | 0 | 5 | 0 | 2 | 0 | 4 | 2 | 0 | 8.5 | 5.6 | 14.1 | 7.8 | 0.0 | 1.4 | 1.57 |
| Shawn Camp |   | mr | 31 | 2 | 0 | 6 | 3 | 2 | 0 | 5 | 1 | 0 | 14.2 | 4.0 | 18.9 | 8.1 | 1.6 | 2.0 | 2.02 |
| Jorge Campillo |   | mr | 28 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 12.1 | 4.0 | 16.9 | 6.1 | 1.3 | 1.5 | 1.80 |
| Jose Capellan |   | mr | 26 | 3 | 1 | 2 | 1 | 3 | 0 | 0 | 1 | 0 | 9.7 | 3.1 | 13.2 | 6.9 | 2.4 | 2.2 | 1.42 |
| Matt Capps | MUL | mr | 23 | 1 | 0 | 10 | 3 | 1 | 0 | 3 | 2 | 0 | 7.3 | 1.8 | 9.5 | 7.3 | 0.6 | 4.0 | 1.01 |
| Chris Capuano* |   | sp | 28 | 6 | 0 | 2 | 8 | 10 | 0 | 10 | 3 | 0 | 10.2 | 3.2 | 13.9 | 7.9 | 1.2 | 2.4 | 1.49 |
| Buddy Carlyle |   | sp | 29 | 4 | 2 | 8 | 2 | 3 | 0 | 11 | 5 | 0 | 9.8 | 2.7 | 12.7 | 6.2 | 1.6 | 2.3 | 1.39 |
| Fausto Carmona | GEO | sp | 23 | 13 | 5 | 2 | 11 | 5 | 1 | 2 | 4 | 0 | 8.3 | 2.6 | 11.3 | 5.7 | 0.7 | 2.2 | 1.21 |
| Chris Carpenter | CRH | sp | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 13.5 | 1.5 | 16.5 | 4.5 | 0.0 | 3.0 | 1.67 |
| Hector Carrasco |   | mr | 37 | 0 | 0 | 1 | 1 | 3 | 0 | 0 | 1 | 0 | 10.3 | 5.4 | 16.0 | 7.7 | 1.9 | 1.4 | 1.75 |
| Marcos Carvajal |   | mr | 22 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 18.0 | 4.5 | 22.5 | 4.5 | 0.0 | 1.0 | 2.50 |
| Santiago Casilla | OTR | mr | 26 | 9 | 0 | 6 | 1 | 5 | 0 | 0 | 3 | 0 | 7.6 | 4.1 | 11.9 | 9.2 | 1.1 | 2.3 | 1.30 |
| Jack Cassel |   | sp | 26 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 11.9 | 2.0 | 14.3 | 4.4 | 0.4 | 2.2 | 1.54 |
| Fabio Castro* |   | mr | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 9.8 | 16.5 | 10.5 | 1.5 | 1.1 | 1.83 |
| Troy Cate* |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 10.1 | 5.1 | 15.2 | 6.8 | 0.6 | 1.3 | 1.69 |
| Andy Cavazos |   | mr | 26 | 0 | 0 | 0 | 2 | 2 | 0 | 2 | 3 | 0 | 12.1 | 7.2 | 20.3 | 6.8 | 2.3 | 0.9 | 2.15 |
| Gustavo Chacin* |   | sp | 26 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 9.5 | 2.3 | 12.5 | 3.6 | 2.0 | 1.6 | 1.32 |
| Shawn Chacon |   | mr | 29 | 7 | 4 | 11 | 7 | 1 | 0 | 10 | 4 | 0 | 8.9 | 4.5 | 14.1 | 7.4 | 0.8 | 1.6 | 1.49 |
| Joba Chamberlain |   | mr | 21 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 4.5 | 2.3 | 7.1 | 12.8 | 0.4 | 5.7 | 0.75 |
| Bruce Chen* |   | mr | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.9 | 5.4 | 15.3 | 6.3 | 2.7 | 1.2 | 1.70 |
| Rocky Cherry |   | mr | 27 | 1 | 0 | 2 | 3 | 0 | 0 | 2 | 2 | 0 | 8.6 | 5.5 | 14.9 | 6.6 | 1.1 | 1.2 | 1.56 |
| Matt Chico* |   | sp | 24 | 9 | 6 | 3 | 5 | 7 | 0 | 6 | 10 | 0 | 9.9 | 4.0 | 14.1 | 5.1 | 1.4 | 1.3 | 1.54 |
| Randy Choate* |   | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 99.0 | 0.0 | 99.0 | 0.0 | 0.0 | 0.0 | 0.00 |
| Vinnie Chulk |   | mr | 28 | 2 | 1 | 2 | 2 | 2 | 0 | 1 | 4 | 0 | 9.0 | 2.4 | 11.7 | 7.0 | 0.5 | 2.9 | 1.26 |
| Darren Clarke |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 6.8 | 20.3 | 6.8 | 0.0 | 1.0 | 2.25 |
| Roger Clemens | ROK | sp | 44 | 15 | 4 | 0 | 5 | 7 | 0 | 2 | 3 | 0 | 9.0 | 2.8 | 12.3 | 6.2 | 0.8 | 2.2 | 1.31 |
| Tyler Clippard |   | sp | 22 | 5 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 9.7 | 5.7 | 15.3 | 6.0 | 2.0 | 1.1 | 1.70 |
| Todd Coffey |   | mr | 26 | 6 | 0 | 4 | 5 | 4 | 0 | 1 | 0 | 0 | 12.4 | 3.4 | 16.6 | 7.6 | 2.1 | 2.3 | 1.75 |
| Willie Collazo* |   | mr | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 11.1 | 7.9 | 19.1 | 0.0 | 0.0 | 0.0 | 2.12 |
| Jesus Colome |   | mr | 29 | 3 | 0 | 3 | 1 | 4 | 0 | 4 | 6 | 0 | 8.7 | 3.7 | 12.5 | 5.9 | 0.8 | 1.6 | 1.38 |
| Bartolo Colon |   | sp | 34 | 2 | 2 | 1 | 5 | 1 | 0 | 4 | 3 | 0 | 12.0 | 2.6 | 15.0 | 6.9 | 1.4 | 2.6 | 1.62 |
| Steve Colyer* |   | mr | 28 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 22.1 | 9.8 | 31.9 | 9.8 | 2.5 | 1.0 | 3.55 |
| Clay Condrey |   | mr | 31 | 1 | 1 | 3 | 5 | 1 | 0 | 1 | 3 | 0 | 11.0 | 2.9 | 14.8 | 4.9 | 0.7 | 1.7 | 1.54 |
| Jose Contreras |   | sp | 35 | 25 | 6 | 1 | 15 | 3 | 0 | 8 | 10 | 0 | 11.0 | 3.0 | 14.7 | 5.4 | 1.0 | 1.8 | 1.56 |
| Aaron Cook | MAD | sp | 28 | 8 | 2 | 6 | 6 | 0 | 0 | 6 | 3 | 0 | 9.7 | 2.4 | 12.4 | 3.3 | 0.8 | 1.4 | 1.34 |
| Tim Corcoran |   | mr | 29 | 0 | 1 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 8.8 | 6.2 | 15.6 | 3.1 | 1.0 | 0.5 | 1.67 |
| Chad Cordero |   | cl | 25 | 2 | 2 | 3 | 0 | 5 | 1 | 2 | 1 | 0 | 9.0 | 3.5 | 12.5 | 7.4 | 1.0 | 2.1 | 1.39 |
| Francisco Cordero | CRH | cl | 32 | 3 | 0 | 1 | 1 | 2 | 0 | 2 | 1 | 0 | 7.4 | 2.6 | 10.1 | 12.2 | 0.6 | 4.8 | 1.11 |
| Bryan Corey |   | mr | 33 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.8 | 3.9 | 9.6 | 5.8 | 0.0 | 1.5 | 1.07 |
| Lance Cormier |   | sp | 26 | 4 | 0 | 3 | 0 | 4 | 0 | 3 | 0 | 0 | 11.0 | 4.3 | 15.4 | 5.3 | 3.2 | 1.2 | 1.71 |
| Rheal Cormier* |   | mr | 40 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 12.0 | 3.0 | 18.0 | 3.0 | 3.0 | 1.0 | 1.67 |
| Manny Corpas | MUL | mr | 24 | 0 | 3 | 3 | 2 | 0 | 0 | 2 | 1 | 0 | 7.3 | 2.3 | 9.8 | 6.7 | 0.7 | 2.9 | 1.06 |
| Kevin Correia | MUL | mr | 26 | 10 | 3 | 7 | 2 | 1 | 1 | 4 | 3 | 0 | 8.3 | 3.5 | 12.0 | 7.1 | 0.8 | 2.0 | 1.32 |
| Neal Cotts* |   | mr | 27 | 1 | 1 | 0 | 3 | 0 | 0 | 1 | 2 | 0 | 8.1 | 4.9 | 14.6 | 7.6 | 0.5 | 1.6 | 1.44 |
| Jon Coutlangus* |   | mr | 26 | 3 | 1 | 0 | 4 | 6 | 0 | 2 | 2 | 0 | 8.3 | 5.9 | 15.1 | 8.3 | 0.7 | 1.4 | 1.59 |
| Jesse Crain |   | mr | 25 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 10.5 | 2.2 | 13.2 | 5.5 | 2.2 | 2.5 | 1.41 |
| Juan Cruz | TON | mr | 28 | 2 | 2 | 3 | 5 | 1 | 2 | 2 | 2 | 1 | 6.6 | 4.7 | 12.1 | 12.8 | 1.0 | 2.7 | 1.26 |
| John Danks* | EDG | sp | 22 | 10 | 1 | 4 | 4 | 3 | 0 | 7 | 4 | 0 | 10.4 | 3.5 | 14.1 | 7.1 | 1.8 | 2.0 | 1.54 |
| Dave Davidson* |   | mr | 23 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 27.0 | 9.0 | 45.0 | 0.0 | 4.5 | 0.0 | 4.00 |
| Kyle Davies |   | sp | 23 | 14 | 3 | 4 | 5 | 8 | 1 | 5 | 3 | 0 | 10.3 | 4.6 | 15.2 | 6.6 | 1.5 | 1.4 | 1.65 |
| Doug Davis* |   | sp | 31 | 6 | 6 | 7 | 5 | 10 | 1 | 10 | 2 | 0 | 9.9 | 4.4 | 14.5 | 6.7 | 1.0 | 1.5 | 1.59 |
| Jason Davis |   | mr | 27 | 2 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 0 | 10.2 | 6.1 | 16.8 | 4.6 | 1.0 | 0.8 | 1.81 |
| Kane Davis |   | mr | 32 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 13.5 | 6.4 | 19.9 | 7.9 | 1.6 | 1.3 | 2.21 |
| Dewon Day |   | mr | 26 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 14.3 | 6.8 | 22.5 | 5.3 | 0.8 | 0.8 | 2.33 |
| Jordan De Jong |   | mr | 28 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.0 | 5.0 | 16.0 | 7.0 | 0.0 | 1.4 | 1.78 |
| Eulogio De La Cruz |   | mr | 23 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 13.5 | 5.4 | 18.9 | 6.8 | 1.3 | 1.3 | 2.10 |
| Jorge De La Rosa* |   | sp | 26 | 6 | 4 | 6 | 3 | 4 | 1 | 2 | 4 | 0 | 11.1 | 3.7 | 15.0 | 5.7 | 1.4 | 1.5 | 1.64 |
| Manny Delcarmen | GEO | mr | 25 | 2 | 2 | 1 | 2 | 0 | 0 | 2 | 2 | 0 | 5.7 | 3.5 | 9.6 | 8.4 | 0.8 | 2.4 | 1.02 |
| Ryan Dempster | CRH | cl | 30 | 9 | 0 | 4 | 1 | 2 | 1 | 3 | 2 | 0 | 8.0 | 4.0 | 12.1 | 7.4 | 1.1 | 1.8 | 1.33 |
| Julio DePaula |   | mr | 24 | 0 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 0 | 13.5 | 4.5 | 19.3 | 3.6 | 2.3 | 0.8 | 2.00 |
| Matt DeSalvo |   | sp | 26 | 4 | 0 | 0 | 3 | 2 | 0 | 1 | 0 | 1 | 11.1 | 5.9 | 17.9 | 3.3 | 0.7 | 0.6 | 1.88 |
| Elmer Dessens |   | mr | 36 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 11.9 | 3.2 | 15.1 | 5.8 | 1.6 | 1.8 | 1.68 |
| Ross Detwiler* |   | mr | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 9.0 | 0.0 | 99.0 | 0.00 |
| Joey Devine |   | mr | 23 | 0 | 0 | 2 | 0 | 1 | 0 | 1 | 1 | 0 | 7.6 | 8.6 | 16.2 | 7.6 | 0.0 | 0.9 | 1.80 |
| Lenny DiNardo* |   | sp | 27 | 3 | 3 | 2 | 3 | 2 | 0 | 7 | 6 | 0 | 9.3 | 3.4 | 13.0 | 4.0 | 0.9 | 1.2 | 1.42 |
| Scott Dohmann |   | mr | 29 | 3 | 2 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 8.0 | 5.0 | 12.9 | 7.2 | 0.8 | 1.4 | 1.44 |
| Brendan Donnelly |   | mr | 35 | 2 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 8.3 | 2.2 | 12.2 | 6.5 | 0.0 | 3.0 | 1.16 |
| Octavio Dotel |   | cl | 33 | 2 | 0 | 4 | 4 | 2 | 0 | 1 | 0 | 1 | 8.5 | 3.5 | 13.2 | 12.0 | 1.2 | 3.4 | 1.34 |
| Dennis Dove |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 3.0 | 18.0 | 3.0 | 6.0 | 1.0 | 2.00 |
| Scott Downs* | EDG | mr | 31 | 0 | 1 | 3 | 1 | 2 | 1 | 1 | 2 | 0 | 7.3 | 3.7 | 11.2 | 8.8 | 0.5 | 2.4 | 1.22 |
| Cory Doyne |   | mr | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 17.2 | 7.4 | 27.0 | 4.9 | 2.5 | 0.7 | 2.73 |
| Travis Driskill |   | mr | 35 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 15.0 | 1.5 | 16.5 | 6.0 | 1.5 | 4.0 | 1.83 |
| Justin Duchscherer | COP | mr | 29 | 3 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 0 | 9.9 | 4.4 | 14.3 | 7.2 | 1.7 | 1.6 | 1.59 |
| Brandon Duckworth |   | mr | 31 | 1 | 0 | 2 | 1 | 7 | 0 | 1 | 1 | 0 | 9.8 | 4.4 | 14.5 | 4.0 | 0.6 | 0.9 | 1.59 |
| Zach Duke* |   | sp | 24 | 5 | 5 | 2 | 3 | 0 | 1 | 2 | 4 | 0 | 13.5 | 2.1 | 15.8 | 3.4 | 1.2 | 1.6 | 1.73 |
| Phil Dumatrait* |   | sp | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 0 | 19.5 | 6.0 | 26.0 | 4.5 | 3.0 | 0.8 | 2.83 |
| Chad Durbin |   | sp | 29 | 5 | 2 | 4 | 8 | 2 | 0 | 1 | 7 | 0 | 9.4 | 3.5 | 13.4 | 4.7 | 1.5 | 1.3 | 1.43 |
| J.D. Durbin |   | sp | 25 | 3 | 1 | 4 | 2 | 2 | 0 | 4 | 1 | 0 | 10.7 | 5.1 | 16.1 | 5.5 | 0.8 | 1.1 | 1.76 |
| Adam Eaton |   | sp | 29 | 6 | 9 | 4 | 11 | 6 | 0 | 10 | 5 | 0 | 10.7 | 4.0 | 15.3 | 5.4 | 1.7 | 1.4 | 1.63 |
| Scott Elarton |   | sp | 31 | 2 | 0 | 0 | 3 | 2 | 0 | 0 | 3 | 1 | 12.9 | 5.1 | 18.7 | 3.2 | 2.9 | 0.6 | 2.00 |
| Alan Embree* | BON | cl | 37 | 4 | 1 | 5 | 0 | 0 | 0 | 1 | 4 | 0 | 8.9 | 2.5 | 11.4 | 6.8 | 0.7 | 2.7 | 1.26 |
| John Ennis |   | cl | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.1 | 3.5 | 17.6 | 9.4 | 1.2 | 2.7 | 1.96 |
| Kelvim Escobar | BON | sp | 31 | 17 | 3 | 2 | 3 | 9 | 0 | 5 | 4 | 0 | 8.4 | 3.0 | 11.5 | 7.4 | 0.5 | 2.4 | 1.27 |
| Dana Eveland* |   | mr | 23 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 14.4 | 9.0 | 23.4 | 5.4 | 0.0 | 0.6 | 2.60 |
| Scott Eyre* |   | mr | 35 | 8 | 1 | 5 | 1 | 3 | 0 | 2 | 1 | 0 | 10.1 | 6.0 | 16.3 | 7.7 | 0.5 | 1.3 | 1.80 |
| Willie Eyre |   | mr | 28 | 2 | 2 | 4 | 1 | 5 | 0 | 5 | 1 | 0 | 10.3 | 4.2 | 14.7 | 5.6 | 1.1 | 1.3 | 1.62 |
| Brian Falkenborg |   | mr | 29 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 10.6 | 3.9 | 14.9 | 7.7 | 1.0 | 2.0 | 1.61 |
| Kyle Farnsworth |   | mr | 31 | 9 | 2 | 2 | 2 | 4 | 2 | 1 | 2 | 0 | 9.0 | 4.0 | 13.3 | 7.2 | 1.3 | 1.8 | 1.45 |
| Ryan Feierabend* |   | sp | 21 | 0 | 3 | 2 | 4 | 3 | 0 | 0 | 2 | 0 | 13.3 | 4.2 | 18.2 | 4.9 | 1.8 | 1.2 | 1.95 |
| Scott Feldman | MID | mr | 24 | 6 | 2 | 5 | 3 | 2 | 2 | 0 | 2 | 0 | 10.2 | 7.4 | 18.2 | 4.4 | 0.7 | 0.6 | 1.95 |
| Pedro Feliciano* | MAD | mr | 30 | 3 | 0 | 4 | 5 | 1 | 1 | 2 | 2 | 0 | 6.6 | 4.4 | 11.7 | 8.6 | 0.4 | 2.0 | 1.22 |
| Nate Field |   | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 9.0 | 36.0 | 18.0 | 0.0 | 2.0 | 4.00 |
| Randy Flores* |   | mr | 31 | 2 | 0 | 0 | 3 | 3 | 0 | 4 | 2 | 0 | 11.6 | 2.5 | 14.6 | 7.7 | 0.3 | 3.1 | 1.56 |
| Ron Flores* |   | mr | 27 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 8.2 | 6.1 | 14.3 | 7.6 | 1.0 | 1.3 | 1.58 |
| Gavin Floyd | TON | sp | 24 | 12 | 0 | 0 | 6 | 1 | 0 | 3 | 2 | 0 | 10.9 | 2.4 | 14.1 | 6.3 | 2.2 | 2.6 | 1.49 |
| Josh Fogg |   | sp | 30 | 12 | 2 | 7 | 13 | 3 | 0 | 5 | 5 | 0 | 10.5 | 3.2 | 14.5 | 5.1 | 1.2 | 1.6 | 1.53 |
| Casey Fossum* |   | mr | 29 | 10 | 0 | 1 | 6 | 3 | 0 | 2 | 7 | 0 | 12.9 | 3.2 | 16.8 | 6.3 | 1.8 | 2.0 | 1.79 |
| Jeff Francis* | MAD | sp | 26 | 9 | 4 | 7 | 7 | 1 | 1 | 7 | 4 | 0 | 9.8 | 2.6 | 12.7 | 6.9 | 1.0 | 2.6 | 1.38 |
| Frank Francisco | EDG | mr | 27 | 4 | 4 | 4 | 2 | 8 | 0 | 6 | 1 | 0 | 8.6 | 5.8 | 14.7 | 7.4 | 0.5 | 1.3 | 1.60 |
| Ryan Franklin | LON | mr | 34 | 2 | 2 | 0 | 3 | 2 | 0 | 2 | 2 | 0 | 7.9 | 1.2 | 9.4 | 4.9 | 0.9 | 4.0 | 1.01 |
| Jason Frasor | MID | mr | 29 | 5 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 0 | 7.4 | 3.6 | 11.4 | 9.3 | 0.5 | 2.6 | 1.23 |
| Brian Fuentes* | CCL | cl | 31 | 1 | 1 | 0 | 7 | 2 | 0 | 1 | 1 | 0 | 6.8 | 3.4 | 11.2 | 8.2 | 0.9 | 2.4 | 1.13 |
| Aaron Fultz* | MAD | mr | 33 | 1 | 2 | 2 | 1 | 1 | 0 | 0 | 3 | 0 | 7.5 | 4.4 | 12.2 | 6.8 | 0.5 | 1.6 | 1.32 |
| Kason Gabbard* | CRH | sp | 25 | 5 | 2 | 1 | 7 | 5 | 0 | 1 | 1 | 0 | 7.5 | 4.5 | 12.8 | 6.1 | 0.9 | 1.3 | 1.34 |
| Eric Gagne | GEO | cl | 31 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 8.5 | 3.6 | 12.3 | 8.8 | 0.5 | 2.4 | 1.35 |
| Armando Galarraga |   | mr | 25 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.3 | 7.3 | 15.6 | 6.2 | 2.1 | 0.9 | 1.73 |
| Sean Gallagher |   | mr | 21 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 11.7 | 7.4 | 19.6 | 3.1 | 1.8 | 0.4 | 2.11 |
| Yovani Gallardo | LON | sp | 21 | 4 | 1 | 2 | 2 | 3 | 0 | 4 | 3 | 0 | 8.4 | 3.0 | 11.6 | 8.2 | 0.7 | 2.7 | 1.27 |
| Anderson Garcia |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Freddy Garcia |   | sp | 31 | 5 | 0 | 3 | 5 | 5 | 0 | 4 | 3 | 0 | 11.5 | 2.9 | 15.2 | 7.8 | 1.9 | 2.6 | 1.60 |
| Harvey Garcia |   | mr | 23 | 1 | 0 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 10.2 | 5.1 | 15.3 | 10.9 | 2.2 | 2.1 | 1.70 |
| Lee Gardner | MAD | mr | 32 | 3 | 0 | 4 | 3 | 1 | 0 | 3 | 3 | 0 | 8.7 | 2.2 | 11.3 | 6.3 | 0.2 | 2.9 | 1.21 |
| Jon Garland | COP | sp | 27 | 2 | 6 | 3 | 4 | 1 | 0 | 3 | 7 | 0 | 9.5 | 2.5 | 12.1 | 4.2 | 0.8 | 1.7 | 1.32 |
| Matt Garza | GEO | sp | 23 | 1 | 3 | 4 | 4 | 4 | 0 | 1 | 4 | 0 | 10.4 | 3.5 | 14.3 | 7.3 | 0.9 | 2.1 | 1.54 |
| Chad Gaudin |   | sp | 24 | 12 | 1 | 8 | 8 | 3 | 1 | 3 | 6 | 0 | 9.3 | 4.5 | 14.1 | 7.0 | 0.9 | 1.5 | 1.53 |
| Geoff Geary |   | mr | 30 | 2 | 2 | 6 | 9 | 3 | 0 | 5 | 3 | 0 | 9.6 | 3.3 | 14.2 | 5.1 | 1.1 | 1.5 | 1.44 |
| Justin Germano | CCL | sp | 24 | 18 | 2 | 3 | 8 | 1 | 0 | 4 | 0 | 0 | 9.0 | 2.7 | 12.2 | 5.3 | 0.9 | 2.0 | 1.30 |
| Dan Giese |   | mr | 30 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 7.7 | 1.9 | 9.6 | 6.8 | 3.9 | 3.5 | 1.07 |
| Tom Glavine* | WIZ | sp | 41 | 5 | 8 | 2 | 4 | 2 | 0 | 5 | 2 | 0 | 9.8 | 2.9 | 12.9 | 4.0 | 1.0 | 1.4 | 1.41 |
| Gary Glover |   | mr | 30 | 6 | 2 | 3 | 1 | 2 | 0 | 1 | 3 | 0 | 10.1 | 3.1 | 13.4 | 5.9 | 1.4 | 1.9 | 1.47 |
| Jimmy Gobble* |   | mr | 25 | 2 | 1 | 6 | 2 | 6 | 1 | 1 | 5 | 0 | 9.4 | 3.9 | 13.6 | 8.4 | 1.0 | 2.2 | 1.47 |
| Edgar Gonzalez |   | mr | 24 | 2 | 3 | 4 | 4 | 5 | 1 | 2 | 3 | 1 | 9.7 | 2.5 | 12.5 | 5.5 | 1.6 | 2.2 | 1.35 |
| Enrique Gonzalez |   | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 4.5 | 22.5 | 0.0 | 0.0 | 0.0 | 2.50 |
| Mike Gonzalez* |   | mr | 29 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.9 | 4.2 | 12.2 | 6.9 | 0.0 | 1.6 | 1.35 |
| Tom Gordon |   | mr | 39 | 1 | 1 | 0 | 2 | 1 | 0 | 1 | 2 | 0 | 9.0 | 2.9 | 12.4 | 7.2 | 1.6 | 2.5 | 1.32 |
| Tom Gorzelanny* | LON | sp | 24 | 17 | 5 | 3 | 11 | 5 | 1 | 3 | 9 | 0 | 9.6 | 3.0 | 13.1 | 6.0 | 0.8 | 2.0 | 1.40 |
| Mike Gosling* |   | mr | 26 | 2 | 1 | 8 | 1 | 1 | 0 | 2 | 1 | 0 | 11.5 | 7.6 | 19.4 | 8.7 | 1.4 | 1.1 | 2.12 |
| John Grabow* |   | mr | 28 | 10 | 0 | 2 | 1 | 3 | 0 | 4 | 2 | 0 | 9.8 | 3.3 | 13.2 | 7.3 | 1.0 | 2.2 | 1.45 |
| Sean Green |   | mr | 28 | 0 | 4 | 6 | 3 | 2 | 0 | 4 | 5 | 0 | 10.2 | 4.5 | 15.1 | 7.0 | 0.3 | 1.6 | 1.63 |
| Kevin Gregg | BT | cl | 29 | 3 | 0 | 1 | 6 | 6 | 0 | 3 | 0 | 0 | 6.8 | 4.3 | 11.7 | 9.3 | 0.8 | 2.2 | 1.23 |
| Zack Greinke | COP | mr | 23 | 7 | 3 | 5 | 3 | 3 | 1 | 3 | 4 | 0 | 9.0 | 2.7 | 11.9 | 7.8 | 0.9 | 2.9 | 1.30 |
| Jason Grilli | COP | mr | 30 | 1 | 2 | 1 | 5 | 5 | 0 | 1 | 5 | 1 | 9.2 | 3.6 | 13.3 | 7.0 | 0.6 | 1.9 | 1.42 |
| Lee Gronkiewicz |   | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 4.5 | 9.0 | 4.5 | 2.3 | 1.0 | 1.00 |
| Eddie Guardado* |   | mr | 36 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 10.5 | 2.6 | 13.8 | 5.3 | 1.3 | 2.0 | 1.46 |
| Matt Guerrier | MID | mr | 28 | 6 | 2 | 1 | 5 | 6 | 0 | 0 | 3 | 0 | 7.3 | 2.1 | 9.9 | 7.0 | 0.9 | 3.2 | 1.05 |
| Jeremy Guthrie | MID | sp | 28 | 4 | 5 | 2 | 4 | 8 | 1 | 4 | 6 | 0 | 8.5 | 2.4 | 11.1 | 6.3 | 1.2 | 2.6 | 1.21 |
| Juan Gutierrez |   | mr | 23 | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 3 | 0 | 10.5 | 2.5 | 13.1 | 6.8 | 1.3 | 2.7 | 1.45 |
| Angel Guzman |   | mr | 25 | 4 | 0 | 0 | 2 | 3 | 0 | 1 | 1 | 0 | 9.5 | 2.7 | 12.8 | 7.7 | 0.6 | 2.9 | 1.35 |
| Marc Gwyn |   | cl | 29 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 15.2 | 8.4 | 23.6 | 5.1 | 5.1 | 0.6 | 2.63 |
| Charlie Haeger |   | mr | 23 | 2 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 0 | 13.5 | 6.4 | 20.6 | 0.8 | 2.4 | 0.1 | 2.21 |
| Roy Halladay | ROK | sp | 30 | 20 | 7 | 3 | 3 | 4 | 0 | 2 | 7 | 0 | 9.3 | 1.9 | 11.3 | 5.6 | 0.6 | 2.9 | 1.24 |
| Cole Hamels* | BT | sp | 23 | 14 | 2 | 4 | 3 | 5 | 0 | 5 | 5 | 0 | 8.0 | 2.1 | 10.3 | 8.7 | 1.2 | 4.1 | 1.12 |
| Jason Hammel | EDG | sp | 24 | 16 | 3 | 1 | 2 | 3 | 0 | 2 | 0 | 0 | 10.6 | 4.2 | 15.0 | 6.8 | 1.3 | 1.6 | 1.65 |
| Justin Hampson* | CCL | mr | 27 | 5 | 2 | 4 | 3 | 0 | 0 | 1 | 1 | 0 | 8.1 | 2.7 | 11.3 | 5.7 | 0.2 | 2.1 | 1.20 |
| Josh Hancock |   | mr | 29 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 9.9 | 3.6 | 13.5 | 6.4 | 1.4 | 1.8 | 1.50 |
| Joel Hanrahan | CCL | sp | 25 | 4 | 2 | 0 | 0 | 3 | 0 | 2 | 1 | 0 | 10.4 | 6.7 | 17.1 | 7.6 | 1.6 | 1.1 | 1.90 |
| Devern Hansack |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.6 | 5.9 | 16.4 | 5.9 | 2.3 | 1.0 | 1.83 |
| J.A. Happ* |   | sp | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.8 | 4.5 | 20.3 | 11.3 | 6.8 | 2.5 | 2.25 |
| Aaron Harang | GEO | sp | 29 | 13 | 8 | 3 | 8 | 12 | 1 | 4 | 5 | 0 | 8.3 | 2.0 | 10.6 | 8.5 | 1.1 | 4.2 | 1.14 |
| Rich Harden | COP | sp | 25 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6.3 | 3.9 | 10.2 | 9.5 | 1.1 | 2.5 | 1.13 |
| Dan Haren | LON | sp | 26 | 20 | 6 | 1 | 3 | 10 | 0 | 2 | 8 | 0 | 8.6 | 2.2 | 11.0 | 7.8 | 1.0 | 3.5 | 1.21 |
| Tim Harikkala |   | sp | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24.3 | 2.7 | 27.0 | 5.4 | 0.0 | 2.0 | 3.00 |
| Kevin Hart |   | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.7 | 3.3 | 9.0 | 10.6 | 0.0 | 3.3 | 1.00 |
| LaTroy Hawkins | BT | mr | 34 | 2 | 1 | 1 | 0 | 2 | 0 | 2 | 1 | 0 | 8.5 | 2.6 | 11.1 | 4.7 | 1.0 | 1.8 | 1.23 |
| Aaron Heilman | WIZ | mr | 28 | 8 | 2 | 1 | 5 | 2 | 0 | 4 | 2 | 0 | 7.5 | 2.1 | 10.2 | 6.6 | 0.8 | 3.2 | 1.07 |
| Mark Hendrickson* | MUL | mr | 33 | 11 | 2 | 4 | 1 | 4 | 0 | 12 | 4 | 0 | 10.4 | 2.1 | 12.6 | 6.8 | 1.1 | 3.2 | 1.39 |
| Sean Henn* |   | mr | 26 | 0 | 1 | 1 | 3 | 1 | 0 | 1 | 0 | 0 | 10.8 | 6.6 | 18.2 | 6.9 | 1.5 | 1.0 | 1.94 |
| Brad Hennessey |   | cl | 27 | 4 | 1 | 1 | 3 | 2 | 0 | 4 | 0 | 0 | 8.7 | 3.0 | 12.1 | 5.3 | 0.9 | 1.7 | 1.30 |
| Clay Hensley |   | sp | 27 | 10 | 1 | 2 | 1 | 4 | 1 | 2 | 1 | 0 | 11.2 | 5.8 | 17.1 | 5.4 | 0.9 | 0.9 | 1.88 |
| Matt Herges | LON | mr | 37 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 1 | 0 | 6.3 | 2.8 | 9.1 | 5.5 | 0.7 | 2.0 | 1.01 |
| Felix Hernandez | ROK | sp | 21 | 10 | 5 | 4 | 3 | 7 | 1 | 6 | 1 | 0 | 9.9 | 2.5 | 12.5 | 7.8 | 0.9 | 3.1 | 1.38 |
| Livan Hernandez |   | sp | 32 | 20 | 5 | 1 | 6 | 3 | 2 | 17 | 8 | 0 | 10.9 | 3.5 | 14.6 | 4.0 | 1.5 | 1.1 | 1.60 |
| Orlando Hernandez | Pal | sp | 37 | 14 | 6 | 4 | 5 | 2 | 0 | 8 | 3 | 0 | 6.6 | 3.9 | 10.8 | 7.8 | 1.4 | 2.0 | 1.17 |
| Roberto Hernandez |   | mr | 42 | 2 | 1 | 3 | 3 | 7 | 0 | 3 | 1 | 0 | 11.5 | 4.9 | 16.9 | 6.0 | 1.0 | 1.2 | 1.81 |
| Yoel Hernandez |   | mr | 27 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 11.7 | 0.6 | 12.3 | 7.6 | 1.2 | 13.0 | 1.37 |
| Rich Hill* | BT | sp | 27 | 23 | 5 | 3 | 12 | 1 | 1 | 9 | 4 | 0 | 7.8 | 2.9 | 11.3 | 8.4 | 1.2 | 2.9 | 1.19 |
| Shawn Hill | WIZ | sp | 26 | 6 | 3 | 2 | 5 | 2 | 0 | 2 | 1 | 0 | 8.0 | 2.3 | 10.7 | 6.0 | 0.8 | 2.6 | 1.14 |
| Jason Hirsh | WIZ | sp | 25 | 4 | 0 | 5 | 2 | 5 | 1 | 6 | 4 | 0 | 8.3 | 3.8 | 12.3 | 6.0 | 1.4 | 1.6 | 1.34 |
| Luke Hochevar |   | mr | 23 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 0 | 7.8 | 2.8 | 12.8 | 3.6 | 0.7 | 1.3 | 1.18 |
| Jim Hoey |   | mr | 24 | 3 | 0 | 1 | 1 | 1 | 0 | 0 | 4 | 0 | 9.1 | 6.6 | 16.1 | 6.6 | 0.7 | 1.0 | 1.74 |
| Trevor Hoffman | Pal | cl | 39 | 3 | 1 | 5 | 0 | 0 | 0 | 3 | 2 | 0 | 7.7 | 2.4 | 10.0 | 6.9 | 0.3 | 2.9 | 1.12 |
| D.J. Houlton |   | mr | 27 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.0 | 2.3 | 11.3 | 6.8 | 1.6 | 3.0 | 1.25 |
| J.P. Howell* | MID | sp | 24 | 2 | 1 | 0 | 3 | 3 | 0 | 2 | 1 | 0 | 12.2 | 3.7 | 16.4 | 8.6 | 1.4 | 2.3 | 1.76 |
| Bob Howry | COP | mr | 33 | 2 | 0 | 3 | 2 | 1 | 0 | 4 | 1 | 0 | 8.4 | 2.1 | 10.7 | 8.0 | 0.9 | 3.8 | 1.17 |
| Jon Huber |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.3 | 3.2 | 13.5 | 6.4 | 0.8 | 2.0 | 1.50 |
| Luke Hudson |   | sp | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 18.0 | 27.0 | 0.0 | 4.5 | 0.0 | 3.00 |
| Tim Hudson | GEO | sp | 31 | 9 | 4 | 8 | 8 | 5 | 2 | 11 | 6 | 0 | 8.9 | 2.1 | 11.3 | 5.3 | 0.4 | 2.5 | 1.22 |
| Phil Hughes | COP | sp | 21 | 9 | 3 | 0 | 2 | 4 | 0 | 2 | 1 | 0 | 7.9 | 3.6 | 11.8 | 7.2 | 1.0 | 2.0 | 1.28 |
| Eric Hull |   | mr | 27 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.4 | 4.0 | 9.4 | 6.8 | 0.0 | 1.7 | 1.05 |
| Philip Humber |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.6 | 2.6 | 14.1 | 2.6 | 1.3 | 1.0 | 1.57 |
| Kei Igawa* |   | sp | 27 | 1 | 1 | 1 | 4 | 5 | 1 | 0 | 0 | 0 | 10.1 | 4.9 | 15.6 | 7.0 | 2.0 | 1.4 | 1.67 |
| Jason Isringhausen | Pal | cl | 34 | 1 | 0 | 3 | 2 | 3 | 0 | 1 | 1 | 0 | 5.8 | 3.9 | 9.9 | 7.4 | 0.6 | 1.9 | 1.07 |
| Edwin Jackson |   | sp | 23 | 17 | 5 | 3 | 4 | 7 | 1 | 5 | 6 | 0 | 10.9 | 4.9 | 16.0 | 7.2 | 1.1 | 1.5 | 1.76 |
| Chuck James* |   | sp | 25 | 9 | 5 | 5 | 1 | 1 | 1 | 9 | 4 | 0 | 9.1 | 3.2 | 12.4 | 6.5 | 1.8 | 2.0 | 1.38 |
| Casey Janssen | OTR | mr | 25 | 1 | 1 | 2 | 3 | 4 | 0 | 0 | 3 | 0 | 8.3 | 2.5 | 11.1 | 4.8 | 0.5 | 2.0 | 1.20 |
| Bobby Jenks | OTR | cl | 26 | 5 | 0 | 4 | 1 | 4 | 0 | 5 | 3 | 0 | 6.2 | 1.8 | 8.2 | 7.8 | 0.3 | 4.3 | 0.89 |
| Jason Jennings |   | sp | 28 | 15 | 3 | 2 | 2 | 5 | 0 | 6 | 7 | 0 | 10.8 | 3.1 | 14.1 | 6.5 | 1.7 | 2.1 | 1.55 |
| Kelvin Jimenez |   | mr | 26 | 4 | 0 | 1 | 4 | 0 | 0 | 1 | 1 | 0 | 12.0 | 3.6 | 16.5 | 5.1 | 0.4 | 1.4 | 1.74 |
| Ubaldo Jimenez | TON | sp | 23 | 16 | 0 | 4 | 6 | 3 | 0 | 3 | 1 | 0 | 7.7 | 4.1 | 12.4 | 7.5 | 1.1 | 1.8 | 1.30 |
| Jim Johnson |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 13.5 | 9.0 | 22.5 | 4.5 | 0.0 | 0.5 | 2.50 |
| Josh Johnson | LON | sp | 23 | 1 | 1 | 3 | 0 | 1 | 0 | 2 | 1 | 0 | 14.9 | 6.9 | 21.8 | 8.0 | 0.6 | 1.2 | 2.43 |
| Randy Johnson* | ROK | sp | 43 | 4 | 4 | 3 | 4 | 1 | 0 | 4 | 0 | 0 | 8.3 | 2.1 | 11.0 | 11.4 | 1.1 | 5.5 | 1.15 |
| Tyler Johnson* |   | mr | 26 | 0 | 0 | 2 | 3 | 2 | 0 | 1 | 1 | 0 | 7.3 | 3.8 | 11.8 | 5.7 | 0.9 | 1.5 | 1.24 |
| Greg Jones |   | mr | 30 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 10.4 | 5.2 | 16.6 | 5.2 | 2.1 | 1.0 | 1.73 |
| Todd Jones | MUL | cl | 39 | 1 | 0 | 6 | 0 | 3 | 0 | 2 | 0 | 0 | 9.4 | 3.4 | 12.8 | 4.8 | 0.4 | 1.4 | 1.42 |
| Jorge Julio |   | mr | 28 | 12 | 2 | 2 | 3 | 6 | 1 | 2 | 4 | 0 | 9.9 | 4.5 | 14.8 | 8.1 | 1.2 | 1.8 | 1.60 |
| Jair Jurrjens |   | sp | 21 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 7.0 | 3.2 | 10.6 | 3.8 | 1.2 | 1.2 | 1.14 |
| Jeff Karstens |   | mr | 24 | 1 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 0 | 16.6 | 5.5 | 22.1 | 3.1 | 2.5 | 0.6 | 2.45 |
| Scott Kazmir* | GEO | sp | 23 | 12 | 8 | 1 | 7 | 10 | 0 | 6 | 3 | 0 | 8.5 | 3.9 | 12.7 | 10.4 | 0.8 | 2.7 | 1.38 |
| Randy Keisler* |   | sp | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 10.9 | 2.6 | 13.5 | 2.6 | 1.6 | 1.0 | 1.50 |
| Kyle Kendrick |   | sp | 22 | 8 | 2 | 3 | 7 | 0 | 0 | 4 | 2 | 0 | 9.6 | 1.9 | 12.0 | 3.6 | 1.2 | 2.0 | 1.27 |
| Ian Kennedy |   | sp | 22 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.2 | 4.3 | 10.4 | 7.1 | 0.5 | 1.7 | 1.16 |
| Joe Kennedy* |   | mr | 28 | 8 | 5 | 1 | 9 | 9 | 0 | 6 | 9 | 0 | 9.7 | 4.5 | 14.9 | 4.1 | 0.7 | 0.9 | 1.57 |
| Logan Kensing |   | mr | 24 | 2 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 7.4 | 4.7 | 13.5 | 8.8 | 0.0 | 1.9 | 1.35 |
| Bobby Keppel |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 6.8 | 20.3 | 2.3 | 2.3 | 0.3 | 2.25 |
| Byung-Hyun Kim |   | sp | 28 | 23 | 6 | 3 | 16 | 4 | 1 | 4 | 6 | 0 | 10.0 | 5.2 | 16.4 | 8.1 | 1.5 | 1.6 | 1.68 |
| Ray King* |   | mr | 33 | 4 | 1 | 1 | 2 | 2 | 0 | 1 | 2 | 0 | 8.4 | 4.8 | 13.6 | 5.7 | 1.4 | 1.2 | 1.46 |
| Steve Kline* |   | mr | 34 | 2 | 2 | 3 | 2 | 1 | 0 | 3 | 0 | 0 | 11.3 | 3.5 | 15.3 | 3.3 | 0.4 | 0.9 | 1.65 |
| Dan Kolb |   | mr | 32 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 18.0 | 6.0 | 24.0 | 6.0 | 3.0 | 1.0 | 2.67 |
| Shane Komine |   | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 7.0 | 1.2 | 9.4 | 1.2 | 2.3 | 1.0 | 0.91 |
| Mike Koplove |   | mr | 30 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 9.0 | 3.0 | 13.5 | 6.0 | 0.0 | 2.0 | 1.33 |
| John Koronka* |   | sp | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 0 | 13.9 | 4.4 | 19.2 | 1.7 | 0.0 | 0.4 | 2.03 |
| Hong-Chih Kuo* | Pal | sp | 25 | 3 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 10.4 | 4.2 | 14.8 | 8.0 | 0.9 | 1.9 | 1.62 |
| Masumi Kuwata |   | mr | 39 | 4 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 0 | 10.7 | 6.4 | 17.6 | 5.1 | 2.6 | 0.8 | 1.90 |
| John Lackey | COP | sp | 28 | 19 | 6 | 2 | 12 | 9 | 1 | 1 | 1 | 0 | 8.8 | 2.1 | 11.4 | 7.2 | 0.7 | 3.4 | 1.21 |
| Aaron Laffey* | EDG | sp | 22 | 1 | 3 | 0 | 4 | 2 | 1 | 1 | 2 | 0 | 9.9 | 2.2 | 12.8 | 4.6 | 0.4 | 2.1 | 1.34 |
| John Lannan* |   | sp | 22 | 4 | 2 | 1 | 2 | 1 | 0 | 2 | 0 | 0 | 9.3 | 4.4 | 14.3 | 2.6 | 0.8 | 0.6 | 1.53 |
| Juan Lara* |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 6.8 | 20.3 | 13.5 | 6.8 | 2.0 | 2.25 |
| Brian Lawrence |   | sp | 31 | 5 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 13.3 | 4.0 | 17.7 | 5.6 | 1.2 | 1.4 | 1.93 |
| Brandon League |   | mr | 24 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 14.7 | 5.4 | 20.1 | 5.4 | 0.8 | 1.0 | 2.23 |
| Wilfredo Ledezma* |   | mr | 26 | 7 | 3 | 4 | 0 | 3 | 2 | 2 | 3 | 0 | 10.6 | 5.8 | 16.4 | 7.1 | 1.1 | 1.2 | 1.82 |
| Cliff Lee* | MID | sp | 28 | 4 | 1 | 1 | 7 | 5 | 0 | 3 | 2 | 0 | 10.4 | 3.3 | 14.3 | 6.1 | 1.6 | 1.8 | 1.52 |
| Jon Leicester |   | sp | 28 | 2 | 0 | 0 | 3 | 1 | 0 | 1 | 1 | 0 | 10.1 | 3.7 | 14.6 | 4.5 | 0.8 | 1.2 | 1.53 |
| Anthony Lerew |   | sp | 24 | 1 | 0 | 1 | 0 | 1 | 0 | 3 | 0 | 0 | 10.8 | 5.4 | 16.2 | 6.9 | 3.1 | 1.3 | 1.80 |
| Jon Lester* | EDG | sp | 23 | 4 | 2 | 0 | 1 | 1 | 0 | 1 | 5 | 0 | 8.7 | 4.4 | 13.3 | 7.1 | 1.4 | 1.6 | 1.46 |
| Colby Lewis |   | mr | 27 | 1 | 0 | 3 | 3 | 1 | 1 | 1 | 2 | 0 | 10.5 | 3.3 | 14.6 | 5.5 | 1.7 | 1.6 | 1.54 |
| Jensen Lewis |   | mr | 23 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 0 | 8.0 | 3.1 | 11.4 | 10.4 | 0.3 | 3.4 | 1.23 |
| Brad Lidge | Pal | cl | 30 | 3 | 0 | 4 | 4 | 6 | 0 | 5 | 1 | 0 | 7.3 | 4.0 | 11.8 | 11.8 | 1.2 | 2.9 | 1.25 |
| Jon Lieber | MUL | sp | 37 | 2 | 0 | 5 | 3 | 1 | 1 | 2 | 4 | 0 | 10.5 | 2.5 | 13.4 | 6.2 | 0.8 | 2.5 | 1.45 |
| Ted Lilly* | OTR | sp | 31 | 14 | 4 | 2 | 3 | 7 | 0 | 11 | 9 | 1 | 7.9 | 2.4 | 10.4 | 7.6 | 1.2 | 3.2 | 1.14 |
| Tim Lincecum | WIZ | sp | 23 | 10 | 2 | 5 | 2 | 10 | 0 | 5 | 7 | 0 | 7.5 | 4.0 | 11.6 | 9.2 | 0.7 | 2.3 | 1.28 |
| Matt Lindstrom | MUL | mr | 27 | 1 | 1 | 4 | 3 | 5 | 0 | 3 | 1 | 0 | 8.9 | 2.8 | 12.1 | 8.3 | 0.3 | 3.0 | 1.30 |
| Scott Linebrink |   | mr | 30 | 6 | 3 | 3 | 1 | 6 | 0 | 0 | 0 | 0 | 8.7 | 3.2 | 12.0 | 6.4 | 1.5 | 2.0 | 1.32 |
| Jesse Litsch | EDG | sp | 22 | 6 | 3 | 2 | 7 | 2 | 0 | 3 | 3 | 0 | 9.4 | 2.9 | 12.9 | 4.1 | 1.1 | 1.4 | 1.37 |
| Wes Littleton |   | mr | 24 | 3 | 1 | 1 | 3 | 1 | 0 | 0 | 3 | 0 | 9.0 | 3.0 | 12.6 | 4.5 | 1.1 | 1.5 | 1.33 |
| Bobby Livingston* |   | sp | 24 | 2 | 0 | 0 | 1 | 2 | 1 | 4 | 0 | 0 | 12.3 | 1.3 | 13.7 | 4.3 | 1.3 | 3.4 | 1.51 |
| Radhames Liz |   | mr | 24 | 3 | 1 | 1 | 1 | 3 | 0 | 1 | 1 | 0 | 9.1 | 8.4 | 17.9 | 8.8 | 1.1 | 1.0 | 1.95 |
| Esteban Loaiza |   | sp | 35 | 1 | 0 | 1 | 1 | 0 | 1 | 3 | 1 | 0 | 8.7 | 4.8 | 13.7 | 4.8 | 2.4 | 1.0 | 1.50 |
| Kameron Loe |   | sp | 25 | 11 | 5 | 6 | 4 | 6 | 0 | 1 | 5 | 0 | 10.7 | 3.7 | 14.7 | 5.2 | 0.9 | 1.4 | 1.60 |
| Adam Loewen* |   | sp | 23 | 0 | 0 | 0 | 3 | 1 | 1 | 1 | 0 | 0 | 8.0 | 7.7 | 16.6 | 6.5 | 0.3 | 0.8 | 1.75 |
| Boone Logan* |   | mr | 22 | 7 | 1 | 3 | 0 | 2 | 0 | 2 | 6 | 0 | 10.5 | 3.6 | 14.0 | 6.2 | 1.2 | 1.8 | 1.56 |
| Kyle Lohse | COP | sp | 28 | 12 | 8 | 3 | 12 | 3 | 0 | 14 | 4 | 0 | 9.7 | 2.7 | 12.9 | 5.7 | 1.0 | 2.1 | 1.37 |
| Braden Looper | MAD | sp | 32 | 5 | 1 | 2 | 4 | 0 | 3 | 4 | 6 | 0 | 9.4 | 2.6 | 12.2 | 4.5 | 1.1 | 1.7 | 1.34 |
| Aquilino Lopez |   | mr | 32 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 9.3 | 3.1 | 13.5 | 3.6 | 1.0 | 1.2 | 1.38 |
| Javier Lopez* | OTR | mr | 29 | 0 | 1 | 2 | 4 | 1 | 0 | 1 | 1 | 0 | 8.0 | 4.0 | 12.8 | 5.8 | 0.4 | 1.4 | 1.33 |
| Rodrigo Lopez | CCL | sp | 31 | 8 | 4 | 6 | 0 | 0 | 0 | 3 | 5 | 0 | 9.4 | 2.4 | 11.8 | 4.9 | 1.2 | 2.0 | 1.31 |
| Derek Lowe | BON | sp | 34 | 14 | 12 | 2 | 1 | 3 | 1 | 6 | 2 | 0 | 8.8 | 2.7 | 11.5 | 6.6 | 0.9 | 2.5 | 1.27 |
| Mark Lowe |   | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 10.1 | 16.9 | 10.1 | 3.4 | 1.0 | 1.88 |
| Noah Lowry* |   | sp | 26 | 7 | 4 | 2 | 5 | 5 | 0 | 14 | 4 | 0 | 8.9 | 5.0 | 14.3 | 5.0 | 0.7 | 1.0 | 1.55 |
| Ruddy Lugo |   | mr | 27 | 2 | 2 | 6 | 2 | 2 | 0 | 3 | 2 | 0 | 8.9 | 6.9 | 16.2 | 6.3 | 0.6 | 0.9 | 1.76 |
| Brandon Lyon | Pal | mr | 27 | 5 | 1 | 2 | 1 | 3 | 1 | 3 | 2 | 0 | 8.5 | 2.7 | 11.3 | 4.9 | 0.2 | 1.8 | 1.24 |
| Mike MacDougal |   | mr | 30 | 9 | 0 | 3 | 2 | 8 | 0 | 0 | 1 | 0 | 10.6 | 7.0 | 18.1 | 8.3 | 0.6 | 1.2 | 1.96 |
| Greg Maddux | Pal | sp | 41 | 37 | 2 | 3 | 6 | 5 | 0 | 15 | 8 | 0 | 10.0 | 1.1 | 11.5 | 4.7 | 0.6 | 4.2 | 1.24 |
| Ryan Madson | CCL | mr | 26 | 1 | 3 | 4 | 2 | 2 | 2 | 2 | 2 | 0 | 7.7 | 3.7 | 11.7 | 6.9 | 0.8 | 1.9 | 1.27 |
| Ron Mahay* |   | mr | 36 | 1 | 3 | 2 | 1 | 1 | 1 | 3 | 2 | 0 | 7.0 | 5.0 | 12.1 | 7.4 | 0.5 | 1.5 | 1.33 |
| Paul Maholm* |   | sp | 25 | 11 | 6 | 3 | 6 | 5 | 0 | 13 | 6 | 0 | 10.3 | 2.5 | 13.1 | 5.3 | 1.1 | 2.1 | 1.42 |
| John Maine | BT | sp | 26 | 12 | 5 | 3 | 5 | 2 | 0 | 11 | 4 | 0 | 7.9 | 3.5 | 11.7 | 8.5 | 1.1 | 2.4 | 1.27 |
| Gary Majewski |   | mr | 27 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 16.8 | 1.2 | 18.8 | 3.9 | 1.2 | 3.3 | 2.00 |
| Shaun Marcum | COP | sp | 25 | 6 | 2 | 1 | 5 | 1 | 0 | 3 | 3 | 1 | 8.4 | 2.8 | 11.5 | 6.9 | 1.5 | 2.5 | 1.25 |
| Carlos Marmol | WIZ | mr | 24 | 9 | 0 | 3 | 4 | 5 | 1 | 1 | 2 | 0 | 5.3 | 4.5 | 10.4 | 12.5 | 0.4 | 2.7 | 1.10 |
| Mike Maroth* |   | sp | 29 | 1 | 6 | 1 | 5 | 2 | 0 | 4 | 6 | 0 | 13.0 | 3.9 | 17.3 | 3.9 | 2.0 | 1.0 | 1.87 |
| Jason Marquis | MUL | sp | 28 | 20 | 2 | 6 | 13 | 3 | 0 | 13 | 1 | 0 | 8.9 | 3.6 | 13.1 | 5.1 | 1.0 | 1.4 | 1.39 |
| Jay Marshall* |   | mr | 24 | 1 | 0 | 6 | 4 | 2 | 0 | 3 | 1 | 0 | 10.7 | 4.7 | 16.3 | 3.9 | 0.6 | 0.8 | 1.71 |
| Sean Marshall* | LON | sp | 24 | 5 | 2 | 3 | 1 | 4 | 0 | 7 | 2 | 0 | 9.3 | 3.0 | 12.5 | 5.8 | 1.1 | 1.9 | 1.37 |
| Damaso Marte* | WIZ | mr | 32 | 0 | 1 | 1 | 2 | 0 | 1 | 0 | 2 | 0 | 6.4 | 3.6 | 10.3 | 10.1 | 0.4 | 2.8 | 1.10 |
| Tom Martin* |   | mr | 37 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 11.2 | 3.2 | 14.7 | 3.5 | 1.4 | 1.1 | 1.60 |
| Carlos Martinez |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 3.4 | 16.9 | 6.8 | 10.1 | 2.0 | 1.88 |
| Pedro Martinez |   | sp | 35 | 3 | 0 | 1 | 2 | 1 | 0 | 1 | 2 | 0 | 10.6 | 2.3 | 13.5 | 10.3 | 0.0 | 4.6 | 1.43 |
| Nick Masset |   | mr | 25 | 8 | 1 | 5 | 2 | 4 | 0 | 1 | 3 | 0 | 11.9 | 5.9 | 18.3 | 4.8 | 0.5 | 0.8 | 1.98 |
| Tom Mastny |   | mr | 26 | 4 | 2 | 9 | 2 | 5 | 0 | 3 | 2 | 0 | 9.8 | 5.0 | 15.1 | 8.1 | 0.9 | 1.6 | 1.65 |
| Julio Mateo |   | mr | 29 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 3.8 | 12.8 | 3.0 | 0.0 | 0.8 | 1.42 |
| Daisuke Matsuzaka | OTR | sp | 26 | 18 | 7 | 1 | 13 | 5 | 0 | 3 | 2 | 0 | 8.4 | 3.5 | 12.5 | 8.8 | 1.1 | 2.5 | 1.32 |
| Marcus McBeth |   | mr | 26 | 7 | 0 | 1 | 1 | 2 | 0 | 2 | 1 | 0 | 10.1 | 3.2 | 13.7 | 7.8 | 0.9 | 2.4 | 1.47 |
| Macay McBride* |   | mr | 24 | 1 | 0 | 0 | 2 | 2 | 0 | 1 | 0 | 0 | 9.1 | 6.9 | 16.5 | 8.3 | 1.1 | 1.2 | 1.78 |
| Brandon McCarthy | EDG | sp | 23 | 17 | 5 | 0 | 3 | 4 | 1 | 3 | 5 | 0 | 9.8 | 4.2 | 14.3 | 5.2 | 0.8 | 1.2 | 1.56 |
| Zach McClellan |   | mr | 28 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 12.9 | 3.2 | 16.1 | 8.4 | 0.0 | 2.6 | 1.79 |
| Seth McClung |   | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 8.3 | 3.8 | 12.8 | 8.3 | 0.0 | 2.2 | 1.33 |
| Dustin McGowan | OTR | sp | 25 | 29 | 1 | 3 | 2 | 13 | 0 | 0 | 6 | 0 | 7.7 | 3.2 | 11.1 | 7.6 | 0.7 | 2.4 | 1.22 |
| Marty McLeary |   | mr | 32 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.6 | 2.3 | 12.9 | 5.9 | 4.7 | 2.5 | 1.43 |
| Mark McLemore* |   | mr | 26 | 1 | 0 | 2 | 1 | 2 | 0 | 0 | 1 | 0 | 9.8 | 4.6 | 14.7 | 9.0 | 1.3 | 1.9 | 1.60 |
| Gil Meche | CRH | sp | 28 | 4 | 5 | 2 | 3 | 3 | 0 | 5 | 7 | 0 | 9.1 | 2.6 | 11.8 | 6.5 | 0.9 | 2.5 | 1.30 |
| Brandon Medders |   | mr | 27 | 0 | 5 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 9.2 | 4.9 | 14.4 | 7.1 | 2.8 | 1.4 | 1.57 |
| Jonathan Meloan |   | mr | 22 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 9.8 | 9.8 | 20.9 | 8.6 | 1.2 | 0.9 | 2.18 |
| Luis Mendoza |   | sp | 23 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 7.3 | 2.3 | 10.7 | 3.9 | 0.6 | 1.8 | 1.06 |
| Cla Meredith |   | mr | 24 | 7 | 2 | 4 | 3 | 3 | 1 | 1 | 3 | 0 | 10.6 | 1.9 | 12.9 | 6.7 | 0.7 | 3.5 | 1.39 |
| Jose Mesa |   | mr | 41 | 1 | 0 | 2 | 2 | 3 | 0 | 2 | 6 | 0 | 9.4 | 4.4 | 14.2 | 5.2 | 1.6 | 1.2 | 1.54 |
| Randy Messenger |   | mr | 25 | 5 | 1 | 5 | 1 | 1 | 0 | 6 | 5 | 0 | 11.9 | 2.9 | 15.0 | 4.8 | 0.6 | 1.6 | 1.65 |
| Dan Meyer* |   | sp | 25 | 1 | 0 | 0 | 0 | 3 | 0 | 1 | 1 | 0 | 11.0 | 5.0 | 16.0 | 6.1 | 1.1 | 1.2 | 1.78 |
| Andrew Miller* | GEO | sp | 22 | 10 | 1 | 0 | 7 | 4 | 1 | 3 | 1 | 0 | 10.3 | 5.5 | 16.7 | 7.9 | 1.1 | 1.4 | 1.75 |
| Jason Miller* |   | mr | 24 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 15.8 | 6.8 | 22.5 | 4.5 | 4.5 | 0.7 | 2.50 |
| Justin Miller |   | mr | 29 | 1 | 2 | 6 | 0 | 4 | 1 | 3 | 0 | 0 | 7.7 | 3.5 | 11.2 | 10.8 | 0.7 | 3.1 | 1.25 |
| Matt Miller |   | mr | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 0.0 | 18.0 | 0.0 | 0.0 | 0.0 | 2.00 |
| Trever Miller* |   | mr | 34 | 3 | 0 | 6 | 4 | 1 | 0 | 3 | 0 | 0 | 8.7 | 4.5 | 14.0 | 8.9 | 1.2 | 2.0 | 1.47 |
| Wade Miller |   | sp | 30 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 15.8 | 4.0 | 19.8 | 4.0 | 3.3 | 1.0 | 2.20 |
| Kevin Millwood |   | sp | 32 | 14 | 5 | 2 | 8 | 4 | 0 | 1 | 4 | 0 | 11.1 | 3.5 | 15.0 | 6.4 | 1.0 | 1.8 | 1.62 |
| Eric Milton* |   | sp | 31 | 2 | 0 | 0 | 0 | 2 | 0 | 3 | 0 | 0 | 11.2 | 2.6 | 13.8 | 5.2 | 1.1 | 2.0 | 1.53 |
| Zach Miner |   | mr | 25 | 4 | 6 | 4 | 0 | 1 | 0 | 4 | 1 | 0 | 9.4 | 3.7 | 13.1 | 5.7 | 0.5 | 1.5 | 1.45 |
| Patrick Misch* |   | mr | 25 | 3 | 1 | 2 | 2 | 0 | 0 | 1 | 2 | 0 | 10.5 | 2.7 | 13.6 | 5.8 | 0.7 | 2.2 | 1.46 |
| Sergio Mitre |   | sp | 26 | 12 | 3 | 3 | 10 | 6 | 0 | 6 | 10 | 0 | 10.9 | 2.5 | 14.0 | 4.8 | 0.5 | 2.0 | 1.48 |
| Brian Moehler |   | mr | 35 | 3 | 0 | 3 | 0 | 1 | 0 | 1 | 1 | 0 | 10.1 | 2.6 | 12.7 | 5.4 | 1.2 | 2.1 | 1.41 |
| Franklin Morales* |   | sp | 21 | 4 | 1 | 1 | 2 | 0 | 0 | 4 | 2 | 0 | 7.8 | 3.2 | 11.4 | 5.9 | 0.5 | 1.9 | 1.22 |
| Juan Morillo |   | mr | 23 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.4 | 2.5 | 12.3 | 7.4 | 2.5 | 3.0 | 1.09 |
| Matt Morris |   | sp | 32 | 15 | 2 | 4 | 9 | 4 | 0 | 10 | 8 | 1 | 10.9 | 2.8 | 14.0 | 4.6 | 0.8 | 1.7 | 1.52 |
| Brandon Morrow | CRH | mr | 22 | 3 | 2 | 5 | 1 | 4 | 0 | 4 | 4 | 0 | 8.0 | 7.1 | 15.2 | 9.4 | 0.4 | 1.3 | 1.67 |
| Dustin Moseley |   | mr | 25 | 6 | 3 | 3 | 3 | 6 | 1 | 1 | 2 | 0 | 9.5 | 2.6 | 12.4 | 4.9 | 0.7 | 1.9 | 1.35 |
| Guillermo Mota |   | mr | 33 | 9 | 0 | 2 | 2 | 2 | 0 | 2 | 0 | 0 | 9.6 | 2.7 | 12.6 | 7.1 | 1.2 | 2.6 | 1.37 |
| Jamie Moyer* |   | sp | 44 | 9 | 6 | 3 | 5 | 2 | 0 | 11 | 5 | 0 | 10.0 | 3.0 | 13.2 | 6.0 | 1.4 | 2.0 | 1.44 |
| Peter Moylan | MAD | mr | 28 | 9 | 2 | 12 | 7 | 2 | 0 | 4 | 4 | 0 | 6.5 | 3.1 | 10.3 | 6.3 | 0.6 | 2.0 | 1.07 |
| Edward Mujica |   | mr | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 13.2 | 1.4 | 14.5 | 4.8 | 2.1 | 3.5 | 1.62 |
| Mark Mulder* |   | sp | 29 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 18.0 | 5.7 | 24.5 | 2.5 | 3.3 | 0.4 | 2.64 |
| Carlos Muniz |   | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 7.7 | 11.6 | 7.7 | 0.0 | 1.0 | 1.29 |
| Arnie Munoz* |   | mr | 25 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 0 | 10.1 | 11.8 | 25.3 | 5.1 | 3.4 | 0.4 | 2.44 |
| Scott Munter |   | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 11.8 | 3.4 | 15.2 | 3.4 | 0.0 | 1.0 | 1.69 |
| Bill Murphy* |   | mr | 26 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 12.8 | 9.9 | 24.2 | 2.8 | 0.0 | 0.3 | 2.53 |
| A.J. Murray* |   | mr | 25 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 8.0 | 4.8 | 12.9 | 5.8 | 1.9 | 1.2 | 1.43 |
| Neal Musser* |   | mr | 26 | 3 | 1 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 11.7 | 5.1 | 16.8 | 6.9 | 1.8 | 1.4 | 1.86 |
| Mike Mussina |   | sp | 38 | 24 | 3 | 2 | 4 | 1 | 0 | 6 | 6 | 0 | 11.1 | 2.1 | 13.4 | 5.4 | 0.8 | 2.6 | 1.47 |
| Brett Myers | CRH | cl | 26 | 6 | 1 | 1 | 1 | 5 | 0 | 3 | 1 | 0 | 8.0 | 3.5 | 11.7 | 10.9 | 1.2 | 3.1 | 1.28 |
| Mike Myers* |   | mr | 38 | 6 | 2 | 2 | 3 | 0 | 1 | 2 | 4 | 0 | 9.8 | 3.8 | 14.1 | 4.5 | 1.0 | 1.2 | 1.51 |
| Joe Nathan | WIZ | cl | 32 | 7 | 0 | 2 | 1 | 3 | 0 | 2 | 2 | 0 | 6.8 | 2.4 | 9.3 | 9.7 | 0.5 | 4.1 | 1.02 |
| Pat Neshek | BON | mr | 26 | 1 | 2 | 5 | 2 | 2 | 0 | 4 | 5 | 0 | 5.6 | 3.5 | 9.3 | 9.5 | 0.9 | 2.7 | 1.01 |
| Josh Newman* |   | mr | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 13.5 | 0.0 | 99.0 | 1.00 |
| Dustin Nippert |   | mr | 26 | 1 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 9.5 | 3.2 | 12.7 | 7.5 | 1.0 | 2.4 | 1.41 |
| Ricky Nolasco |   | sp | 24 | 2 | 1 | 2 | 1 | 1 | 0 | 3 | 5 | 0 | 11.0 | 3.8 | 15.2 | 4.6 | 1.3 | 1.2 | 1.64 |
| Leo Nunez |   | mr | 23 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 9.1 | 2.1 | 11.1 | 7.6 | 1.6 | 3.7 | 1.24 |
| Eric O'Flaherty* | CRH | mr | 22 | 2 | 2 | 1 | 5 | 4 | 1 | 0 | 2 | 0 | 7.7 | 3.4 | 12.0 | 6.2 | 0.2 | 1.8 | 1.24 |
| Wes Obermueller |   | mr | 30 | 6 | 2 | 5 | 4 | 2 | 0 | 0 | 3 | 0 | 11.0 | 5.5 | 17.1 | 5.3 | 1.1 | 1.0 | 1.83 |
| Tomo Ohka |   | sp | 31 | 0 | 1 | 1 | 0 | 2 | 0 | 1 | 1 | 0 | 10.9 | 3.5 | 14.5 | 3.4 | 1.6 | 1.0 | 1.61 |
| Ross Ohlendorf |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.1 | 2.8 | 9.9 | 12.8 | 1.4 | 4.5 | 1.11 |
| Will Ohman* | MAD | mr | 29 | 4 | 0 | 4 | 1 | 2 | 0 | 2 | 0 | 0 | 10.4 | 4.0 | 14.6 | 8.2 | 0.7 | 2.1 | 1.60 |
| Hideki Okajima* | COP | mr | 31 | 5 | 0 | 2 | 1 | 0 | 0 | 5 | 1 | 0 | 6.5 | 2.2 | 8.9 | 8.2 | 0.8 | 3.7 | 0.97 |
| Darren Oliver* |   | mr | 36 | 3 | 0 | 2 | 1 | 1 | 1 | 2 | 4 | 0 | 8.1 | 3.2 | 11.5 | 7.1 | 0.7 | 2.2 | 1.26 |
| Scott Olsen* |   | sp | 23 | 10 | 6 | 4 | 1 | 8 | 0 | 14 | 8 | 0 | 11.5 | 4.3 | 15.9 | 6.8 | 1.5 | 1.6 | 1.76 |
| Garrett Olson* |   | sp | 23 | 3 | 1 | 1 | 2 | 1 | 1 | 0 | 3 | 0 | 11.7 | 7.8 | 20.0 | 7.8 | 1.1 | 1.0 | 2.16 |
| Ramon Ortiz |   | mr | 34 | 8 | 3 | 1 | 6 | 2 | 1 | 1 | 5 | 0 | 11.0 | 1.9 | 13.4 | 4.4 | 1.4 | 2.3 | 1.43 |
| Russ Ortiz |   | sp | 33 | 4 | 2 | 1 | 6 | 0 | 0 | 3 | 1 | 0 | 10.5 | 3.7 | 15.2 | 5.0 | 0.7 | 1.4 | 1.57 |
| Chad Orvella |   | mr | 26 | 3 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 20.3 | 11.3 | 32.6 | 6.8 | 3.4 | 0.6 | 3.50 |
| Franquelis Osoria |   | mr | 25 | 1 | 0 | 2 | 4 | 2 | 0 | 0 | 0 | 0 | 10.5 | 2.5 | 14.3 | 4.1 | 1.0 | 1.6 | 1.45 |
| Roy Oswalt | BT | sp | 29 | 5 | 1 | 6 | 7 | 1 | 1 | 6 | 4 | 0 | 9.4 | 2.5 | 12.2 | 6.5 | 0.6 | 2.6 | 1.33 |
| Akinori Otsuka |   | mr | 35 | 3 | 2 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 7.2 | 2.5 | 9.7 | 6.4 | 0.0 | 2.6 | 1.08 |
| Henry Owens |   | mr | 28 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 7.4 | 3.9 | 11.3 | 6.3 | 1.2 | 1.6 | 1.26 |
| Micah Owings |   | sp | 24 | 4 | 3 | 2 | 14 | 5 | 0 | 7 | 3 | 0 | 8.6 | 2.9 | 12.4 | 6.2 | 1.2 | 2.1 | 1.28 |
| Vicente Padilla |   | sp | 29 | 3 | 3 | 1 | 9 | 2 | 0 | 3 | 2 | 0 | 10.9 | 3.7 | 15.3 | 5.3 | 1.2 | 1.4 | 1.63 |
| Jonathan Papelbon | BON | cl | 26 | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.6 | 2.3 | 7.6 | 13.0 | 0.8 | 5.6 | 0.77 |
| Chan Ho Park |   | sp | 34 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 13.5 | 4.5 | 18.0 | 9.0 | 4.5 | 2.0 | 2.00 |
| Chad Paronto |   | mr | 31 | 6 | 2 | 5 | 3 | 2 | 0 | 2 | 3 | 0 | 10.5 | 4.2 | 15.4 | 3.1 | 0.2 | 0.7 | 1.64 |
| Manny Parra* |   | mr | 24 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 3 | 0 | 8.5 | 4.1 | 13.3 | 8.9 | 0.3 | 2.2 | 1.41 |
| John Parrish* |   | mr | 29 | 0 | 0 | 4 | 2 | 3 | 0 | 1 | 1 | 0 | 10.9 | 6.4 | 17.7 | 7.1 | 0.3 | 1.1 | 1.92 |
| John Patterson |   | sp | 29 | 7 | 1 | 1 | 0 | 4 | 0 | 3 | 1 | 0 | 11.2 | 6.3 | 17.5 | 4.3 | 1.4 | 0.7 | 1.95 |
| Troy Patton* |   | sp | 21 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 7.1 | 2.8 | 11.4 | 5.7 | 2.1 | 2.0 | 1.11 |
| Felipe Paulino |   | sp | 23 | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 10.4 | 3.3 | 13.7 | 5.2 | 2.4 | 1.6 | 1.53 |
| Carl Pavano |   | sp | 31 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.5 | 1.6 | 11.1 | 3.2 | 0.8 | 2.0 | 1.24 |
| Jake Peavy | MUL | sp | 26 | 21 | 2 | 5 | 6 | 4 | 0 | 5 | 7 | 0 | 6.8 | 2.7 | 9.8 | 9.7 | 0.5 | 3.5 | 1.06 |
| Jailen Peguero |   | mr | 26 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 10.4 | 8.0 | 19.0 | 5.5 | 1.2 | 0.7 | 2.05 |
| Mike Pelfrey |   | sp | 23 | 8 | 0 | 1 | 9 | 3 | 0 | 6 | 3 | 0 | 10.5 | 4.8 | 16.5 | 5.6 | 0.7 | 1.2 | 1.71 |
| Tony Pena | LON | mr | 25 | 1 | 0 | 4 | 5 | 3 | 1 | 1 | 3 | 0 | 6.6 | 3.3 | 10.4 | 6.6 | 0.8 | 2.0 | 1.10 |
| Brad Penny | LON | sp | 29 | 14 | 5 | 2 | 5 | 6 | 0 | 13 | 9 | 0 | 8.6 | 3.2 | 12.0 | 5.8 | 0.4 | 1.8 | 1.31 |
| Joel Peralta | MID | mr | 31 | 8 | 0 | 5 | 2 | 2 | 0 | 2 | 4 | 0 | 9.5 | 2.0 | 11.7 | 6.8 | 0.9 | 3.5 | 1.28 |
| Troy Percival | OTR | mr | 37 | 2 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 5.4 | 2.3 | 7.6 | 8.1 | 0.7 | 3.6 | 0.85 |
| Juan Perez* |   | mr | 28 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.2 | 5.8 | 16.1 | 7.3 | 1.5 | 1.3 | 1.78 |
| Odalis Perez* |   | sp | 30 | 9 | 3 | 5 | 4 | 3 | 0 | 6 | 7 | 0 | 11.7 | 3.3 | 15.2 | 4.2 | 0.9 | 1.3 | 1.66 |
| Oliver Perez* | BT | sp | 25 | 13 | 3 | 1 | 7 | 6 | 0 | 4 | 7 | 0 | 7.8 | 4.0 | 12.2 | 8.8 | 1.1 | 2.2 | 1.31 |
| Rafael Perez* | CRH | mr | 25 | 2 | 1 | 2 | 0 | 4 | 0 | 1 | 1 | 0 | 6.1 | 2.2 | 8.3 | 9.2 | 0.7 | 4.1 | 0.92 |
| Glen Perkins* |   | mr | 24 | 1 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 7.2 | 3.8 | 11.6 | 6.3 | 0.6 | 1.7 | 1.22 |
| Yusmeiro Petit |   | sp | 22 | 4 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 9.2 | 2.8 | 12.0 | 6.3 | 1.9 | 2.2 | 1.33 |
| Billy Petrick |   | mr | 23 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.4 | 6.5 | 14.0 | 5.6 | 2.8 | 0.9 | 1.55 |
| Andy Pettitte* |   | sp | 35 | 18 | 8 | 1 | 1 | 3 | 0 | 5 | 9 | 0 | 9.9 | 2.9 | 12.9 | 5.9 | 0.7 | 2.0 | 1.43 |
| Heath Phillips* |   | mr | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.3 | 4.9 | 17.2 | 2.5 | 1.2 | 0.5 | 1.91 |
| Carmen Pignatiello* |   | mr | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 0.0 | 13.5 | 13.5 | 4.5 | 99.0 | 1.50 |
| Joel Pineiro |   | mr | 28 | 4 | 2 | 0 | 2 | 3 | 0 | 3 | 1 | 0 | 10.1 | 2.4 | 12.7 | 5.5 | 1.3 | 2.3 | 1.39 |
| Renyel Pinto* |   | mr | 24 | 2 | 3 | 2 | 3 | 2 | 0 | 1 | 3 | 0 | 6.9 | 4.9 | 12.3 | 8.6 | 1.1 | 1.8 | 1.31 |
| Sidney Ponson |   | sp | 30 | 1 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 12.9 | 4.1 | 17.7 | 5.5 | 1.7 | 1.4 | 1.88 |
| Bret Prinz |   | mr | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10.8 | 5.4 | 16.2 | 2.7 | 2.7 | 0.5 | 1.80 |
| Scott Proctor |   | mr | 30 | 9 | 4 | 4 | 6 | 5 | 1 | 3 | 7 | 0 | 8.1 | 4.6 | 13.3 | 6.7 | 1.3 | 1.5 | 1.41 |
| J.J. Putz | MID | cl | 30 | 3 | 0 | 0 | 2 | 3 | 0 | 2 | 1 | 0 | 4.6 | 1.6 | 6.5 | 10.3 | 0.8 | 6.3 | 0.70 |
| Chad Qualls | BON | mr | 28 | 7 | 5 | 5 | 3 | 2 | 0 | 6 | 2 | 0 | 9.1 | 2.7 | 12.2 | 8.5 | 1.1 | 3.1 | 1.32 |
| Aaron Rakers |   | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Edwar Ramirez |   | mr | 26 | 2 | 0 | 2 | 3 | 4 | 0 | 1 | 1 | 0 | 10.3 | 6.0 | 17.6 | 13.3 | 2.6 | 2.2 | 1.81 |
| Elizardo Ramirez |   | sp | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 11.0 | 4.4 | 15.4 | 4.4 | 2.8 | 1.0 | 1.71 |
| Erasmo Ramirez* |   | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.9 | 4.3 | 14.2 | 1.4 | 0.0 | 0.3 | 1.58 |
| Horacio Ramirez* |   | sp | 27 | 9 | 5 | 1 | 2 | 1 | 0 | 1 | 1 | 1 | 12.8 | 3.9 | 16.8 | 3.7 | 1.2 | 1.0 | 1.85 |
| Ramon Ramirez | LON | mr | 25 | 3 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 0 | 10.9 | 3.1 | 14.5 | 7.8 | 1.0 | 2.5 | 1.56 |
| Stephen Randolph* |   | mr | 33 | 2 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 0 | 14.2 | 11.5 | 26.3 | 14.8 | 2.7 | 1.3 | 2.85 |
| Clay Rapada* |   | mr | 26 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 10.1 | 6.8 | 16.9 | 13.5 | 6.8 | 2.0 | 1.88 |
| Darrell Rasner |   | sp | 26 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 10.6 | 2.9 | 14.2 | 4.0 | 1.5 | 1.4 | 1.50 |
| Jon Rauch | TON | mr | 28 | 5 | 1 | 4 | 0 | 2 | 0 | 2 | 5 | 0 | 7.7 | 2.2 | 9.9 | 7.3 | 0.7 | 3.4 | 1.10 |
| Chris Ray | MID | cl | 25 | 2 | 1 | 2 | 2 | 1 | 0 | 0 | 1 | 0 | 7.4 | 3.8 | 11.6 | 9.3 | 1.1 | 2.4 | 1.24 |
| Tim Redding | CCL | sp | 29 | 5 | 3 | 4 | 4 | 1 | 1 | 6 | 1 | 0 | 9.0 | 4.1 | 13.5 | 5.0 | 1.1 | 1.2 | 1.45 |
| Mark Redman* |   | sp | 33 | 1 | 1 | 2 | 2 | 1 | 1 | 0 | 2 | 1 | 12.8 | 3.7 | 17.0 | 5.9 | 1.3 | 1.6 | 1.84 |
| Chris Reitsma |   | mr | 29 | 4 | 0 | 1 | 0 | 4 | 0 | 2 | 1 | 0 | 14.1 | 3.4 | 17.5 | 4.2 | 1.1 | 1.2 | 1.94 |
| Chris Resop |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 8.3 | 2.1 | 10.4 | 4.2 | 2.1 | 2.0 | 1.15 |
| Al Reyes |   | cl | 37 | 2 | 0 | 1 | 2 | 1 | 0 | 1 | 2 | 0 | 7.3 | 3.1 | 10.7 | 10.4 | 1.9 | 3.3 | 1.15 |
| Anthony Reyes |   | sp | 25 | 4 | 2 | 0 | 9 | 1 | 2 | 1 | 7 | 0 | 9.1 | 3.6 | 13.4 | 6.2 | 1.3 | 1.7 | 1.41 |
| Dennys Reyes* |   | mr | 30 | 1 | 3 | 1 | 2 | 4 | 0 | 3 | 3 | 0 | 10.4 | 6.4 | 17.5 | 6.4 | 0.3 | 1.0 | 1.88 |
| Jo-Jo Reyes* |   | sp | 22 | 2 | 1 | 2 | 1 | 1 | 0 | 5 | 2 | 0 | 9.8 | 5.3 | 15.3 | 4.8 | 1.6 | 0.9 | 1.68 |
| John Rheinecker* |   | mr | 28 | 0 | 0 | 2 | 2 | 3 | 0 | 1 | 1 | 0 | 10.9 | 5.0 | 16.3 | 7.2 | 1.6 | 1.4 | 1.77 |
| Jeff Ridgway* |   | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 189.0 | 27.0 | 243.0 | 0.0 | 27.0 | 0.0 | 24.00 |
| Juan Rincon |   | mr | 28 | 3 | 1 | 3 | 3 | 4 | 0 | 2 | 1 | 0 | 9.8 | 4.2 | 14.5 | 7.4 | 1.4 | 1.8 | 1.56 |
| Royce Ring* |   | mr | 26 | 1 | 1 | 2 | 0 | 2 | 0 | 0 | 1 | 0 | 5.8 | 7.6 | 13.5 | 9.4 | 0.4 | 1.2 | 1.50 |
| David Riske | CRH | mr | 30 | 4 | 1 | 4 | 1 | 0 | 0 | 4 | 3 | 0 | 7.9 | 3.5 | 11.5 | 6.7 | 1.0 | 1.9 | 1.26 |
| Mariano Rivera | ROK | cl | 37 | 2 | 1 | 2 | 6 | 1 | 0 | 1 | 1 | 1 | 8.6 | 1.5 | 10.9 | 9.3 | 0.5 | 6.2 | 1.12 |
| Saul Rivera | BT | mr | 29 | 2 | 2 | 4 | 2 | 4 | 0 | 5 | 4 | 0 | 8.5 | 4.1 | 12.8 | 6.2 | 0.1 | 1.5 | 1.40 |
| Connor Robertson |   | mr | 25 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 27.0 | 9.0 | 40.5 | 9.0 | 0.0 | 1.0 | 4.00 |
| Nate Robertson* |   | sp | 29 | 7 | 4 | 2 | 3 | 5 | 1 | 5 | 6 | 1 | 10.1 | 3.2 | 13.4 | 6.0 | 1.1 | 1.9 | 1.47 |
| Fernando Rodney | OTR | mr | 30 | 6 | 2 | 0 | 3 | 4 | 0 | 4 | 2 | 0 | 8.2 | 3.7 | 12.4 | 9.6 | 0.9 | 2.6 | 1.32 |
| Francisco Rodriguez | BON | cl | 25 | 12 | 1 | 0 | 1 | 7 | 1 | 1 | 4 | 0 | 6.7 | 4.5 | 11.4 | 12.0 | 0.4 | 2.6 | 1.25 |
| Wandy Rodriguez* | MUL | sp | 28 | 13 | 9 | 2 | 5 | 3 | 0 | 6 | 4 | 0 | 8.8 | 3.1 | 12.1 | 7.8 | 1.1 | 2.5 | 1.32 |
| Brian Rogers |   | mr | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 13.5 | 4.5 | 18.0 | 4.5 | 9.0 | 1.0 | 2.00 |
| Kenny Rogers* |   | sp | 42 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 9.3 | 3.6 | 13.0 | 5.1 | 1.1 | 1.4 | 1.43 |
| J.C. Romero* |   | mr | 31 | 4 | 2 | 5 | 2 | 4 | 0 | 1 | 1 | 0 | 6.2 | 6.4 | 12.9 | 6.7 | 0.5 | 1.0 | 1.40 |
| Francisco Rosario |   | mr | 26 | 3 | 1 | 1 | 4 | 1 | 0 | 2 | 2 | 0 | 11.6 | 4.4 | 17.4 | 8.5 | 1.0 | 1.9 | 1.78 |
| Ryan Rowland-Smith* |   | mr | 24 | 0 | 2 | 1 | 2 | 0 | 0 | 1 | 4 | 1 | 9.1 | 3.5 | 13.0 | 9.8 | 0.9 | 2.8 | 1.40 |
| B.J. Ryan* |   | cl | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.5 | 8.3 | 22.8 | 6.2 | 2.1 | 0.8 | 2.54 |
| Jae Kuk Ryu |   | mr | 24 | 2 | 2 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 12.0 | 4.2 | 17.7 | 5.4 | 0.8 | 1.3 | 1.80 |
| Kirk Saarloos |   | mr | 28 | 2 | 0 | 1 | 3 | 1 | 0 | 2 | 0 | 0 | 11.4 | 4.0 | 16.0 | 5.7 | 1.7 | 1.4 | 1.71 |
| C.C. Sabathia* | CRH | sp | 26 | 10 | 10 | 1 | 8 | 1 | 0 | 6 | 6 | 0 | 8.9 | 1.4 | 10.6 | 7.8 | 0.7 | 5.6 | 1.14 |
| Takashi Saito | Pal | cl | 37 | 2 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.6 | 1.8 | 6.9 | 10.9 | 0.7 | 6.0 | 0.72 |
| Juan Salas |   | mr | 28 | 2 | 1 | 0 | 5 | 3 | 0 | 1 | 0 | 0 | 8.9 | 4.2 | 14.4 | 6.4 | 1.7 | 1.5 | 1.46 |
| Brad Salmon |   | mr | 27 | 2 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 8.3 | 3.8 | 12.4 | 8.3 | 1.1 | 2.2 | 1.33 |
| Chris Sampson |   | sp | 29 | 3 | 1 | 2 | 7 | 3 | 0 | 6 | 6 | 0 | 10.2 | 2.2 | 12.9 | 3.8 | 1.5 | 1.7 | 1.38 |
| Brian Sanches |   | mr | 28 | 1 | 2 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 8.0 | 7.4 | 16.0 | 5.5 | 3.7 | 0.8 | 1.70 |
| Anibal Sanchez | MAD | sp | 23 | 1 | 0 | 1 | 2 | 3 | 0 | 2 | 2 | 0 | 12.9 | 5.7 | 19.2 | 4.2 | 0.9 | 0.7 | 2.07 |
| Jonathan Sanchez* |   | mr | 24 | 1 | 4 | 1 | 5 | 4 | 0 | 2 | 2 | 0 | 9.9 | 4.8 | 15.6 | 10.7 | 1.4 | 2.2 | 1.63 |
| Romulo Sanchez |   | mr | 23 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 8.0 | 4.0 | 12.5 | 5.5 | 1.0 | 1.4 | 1.33 |
| Ervin Santana | BON | sp | 24 | 11 | 3 | 3 | 8 | 7 | 0 | 3 | 2 | 0 | 10.4 | 3.5 | 14.4 | 7.6 | 1.6 | 2.2 | 1.55 |
| Johan Santana* | ROK | sp | 28 | 6 | 5 | 0 | 4 | 7 | 1 | 4 | 4 | 0 | 7.5 | 2.1 | 9.8 | 9.7 | 1.4 | 4.5 | 1.07 |
| Victor Santos |   | mr | 30 | 4 | 2 | 6 | 3 | 3 | 0 | 4 | 4 | 0 | 10.1 | 4.7 | 15.2 | 6.8 | 2.1 | 1.5 | 1.64 |
| Dennis Sarfate |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.4 | 1.1 | 6.5 | 15.1 | 0.0 | 14.0 | 0.72 |
| Joe Saunders* | MID | sp | 26 | 7 | 4 | 1 | 1 | 3 | 0 | 0 | 5 | 0 | 10.8 | 2.9 | 13.8 | 5.8 | 0.9 | 2.0 | 1.52 |
| Curt Schilling | Pal | sp | 40 | 5 | 1 | 1 | 2 | 0 | 0 | 4 | 3 | 1 | 9.8 | 1.4 | 11.3 | 6.0 | 1.3 | 4.4 | 1.25 |
| Jason Schmidt |   | sp | 34 | 1 | 0 | 2 | 1 | 2 | 0 | 2 | 0 | 0 | 11.2 | 4.9 | 16.5 | 7.7 | 1.4 | 1.6 | 1.79 |
| Scott Schoeneweis* |   | mr | 33 | 6 | 1 | 5 | 3 | 3 | 1 | 4 | 1 | 0 | 9.5 | 4.3 | 14.2 | 6.3 | 1.2 | 1.5 | 1.53 |
| Chris Schroder | CCL | mr | 28 | 3 | 1 | 1 | 2 | 0 | 0 | 2 | 0 | 0 | 7.1 | 3.0 | 10.5 | 8.5 | 0.4 | 2.9 | 1.13 |
| Mike Schultz |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 9.0 | 0.0 | 99.0 | 1.00 |
| Rudy Seanez |   | mr | 38 | 10 | 1 | 3 | 4 | 2 | 0 | 2 | 3 | 0 | 9.2 | 3.2 | 12.9 | 8.6 | 1.2 | 2.7 | 1.38 |
| Bobby Seay* | ROK | mr | 29 | 1 | 1 | 4 | 2 | 1 | 1 | 2 | 2 | 1 | 7.4 | 2.9 | 10.7 | 7.4 | 0.2 | 2.5 | 1.14 |
| Chris Seddon* |   | sp | 23 | 3 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 15.1 | 2.6 | 18.2 | 5.2 | 1.0 | 2.0 | 1.96 |
| Zack Segovia |   | sp | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 14.4 | 1.8 | 16.2 | 3.6 | 1.8 | 2.0 | 1.80 |
| Aaron Sele |   | mr | 37 | 0 | 0 | 2 | 2 | 0 | 0 | 4 | 5 | 0 | 13.1 | 3.5 | 16.9 | 4.9 | 0.8 | 1.4 | 1.84 |
| Jae Seo |   | sp | 30 | 3 | 2 | 1 | 4 | 1 | 0 | 1 | 1 | 0 | 14.5 | 2.8 | 18.0 | 4.8 | 1.9 | 1.8 | 1.92 |
| Dan Serafini* |   | mr | 33 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0.0 | 54.0 | 81.0 | 0.0 | 0.0 | 0.0 | 6.00 |
| Josh Sharpless |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 14.5 | 2.1 | 16.6 | 2.1 | 6.2 | 1.0 | 1.85 |
| Tom Shearn |   | sp | 29 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 8.8 | 3.6 | 12.4 | 4.4 | 2.2 | 1.2 | 1.38 |
| Ben Sheets | TON | sp | 28 | 21 | 0 | 2 | 1 | 4 | 0 | 4 | 5 | 0 | 8.8 | 2.4 | 11.2 | 6.8 | 1.1 | 2.9 | 1.24 |
| George Sherrill* | ROK | mr | 30 | 0 | 0 | 1 | 1 | 1 | 1 | 4 | 4 | 0 | 5.5 | 3.4 | 9.1 | 11.0 | 0.8 | 3.3 | 0.99 |
| James Shields | BON | sp | 25 | 9 | 6 | 0 | 10 | 9 | 0 | 4 | 5 | 0 | 8.5 | 1.5 | 10.4 | 7.7 | 1.2 | 5.1 | 1.11 |
| Scot Shields | ROK | mr | 31 | 3 | 1 | 0 | 4 | 6 | 0 | 0 | 1 | 0 | 7.2 | 3.9 | 11.6 | 9.0 | 0.8 | 2.3 | 1.23 |
| Brian Shouse* | OTR | mr | 38 | 6 | 2 | 5 | 2 | 0 | 1 | 4 | 2 | 0 | 8.7 | 2.6 | 11.7 | 6.0 | 0.0 | 2.3 | 1.26 |
| Paul Shuey |   | mr | 36 | 2 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 11.6 | 7.4 | 18.9 | 7.7 | 1.1 | 1.0 | 2.10 |
| Carlos Silva | MID | sp | 28 | 8 | 7 | 2 | 4 | 4 | 1 | 6 | 5 | 0 | 10.2 | 1.6 | 12.0 | 4.0 | 0.9 | 2.5 | 1.31 |
| Jason Simontacchi |   | sp | 33 | 0 | 3 | 4 | 3 | 1 | 0 | 4 | 4 | 0 | 12.1 | 2.9 | 15.4 | 5.3 | 1.7 | 1.8 | 1.67 |
| Andrew Sisco* |   | mr | 24 | 3 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 12.2 | 7.1 | 19.9 | 8.4 | 1.3 | 1.2 | 2.14 |
| Doug Slaten* |   | mr | 27 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 10.2 | 3.5 | 13.6 | 6.9 | 1.0 | 2.0 | 1.51 |
| Kevin Slowey |   | sp | 23 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 11.1 | 1.5 | 12.6 | 6.3 | 2.2 | 4.3 | 1.39 |
| Joe Smith | LON | mr | 23 | 5 | 1 | 4 | 7 | 2 | 0 | 2 | 0 | 0 | 9.7 | 4.3 | 15.4 | 9.1 | 0.6 | 2.1 | 1.56 |
| Matt Smith* |   | mr | 28 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 24.8 | 33.8 | 2.3 | 0.0 | 0.1 | 3.75 |
| John Smoltz | WIZ | sp | 40 | 11 | 4 | 9 | 4 | 8 | 0 | 10 | 5 | 1 | 8.6 | 2.1 | 10.8 | 8.6 | 0.8 | 4.2 | 1.18 |
| Ian Snell |   | sp | 25 | 14 | 6 | 4 | 8 | 12 | 0 | 6 | 7 | 1 | 9.0 | 2.9 | 12.3 | 7.7 | 1.0 | 2.6 | 1.33 |
| Kyle Snyder |   | mr | 29 | 5 | 2 | 2 | 6 | 4 | 0 | 1 | 1 | 0 | 7.5 | 5.3 | 13.7 | 6.8 | 1.2 | 1.3 | 1.42 |
| Andy Sonnanstine |   | sp | 24 | 1 | 8 | 2 | 5 | 2 | 0 | 3 | 5 | 0 | 10.4 | 1.8 | 12.5 | 6.7 | 1.2 | 3.7 | 1.35 |
| Joakim Soria | BON | cl | 23 | 0 | 0 | 3 | 1 | 2 | 0 | 1 | 3 | 0 | 6.0 | 2.5 | 8.6 | 9.8 | 0.4 | 3.9 | 0.94 |
| Rafael Soriano | GEO | mr | 27 | 7 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 5.9 | 1.9 | 8.0 | 8.8 | 1.5 | 4.7 | 0.86 |
| Jorge Sosa |   | mr | 30 | 4 | 2 | 2 | 0 | 0 | 0 | 10 | 3 | 0 | 8.7 | 3.3 | 12.0 | 5.5 | 0.8 | 1.7 | 1.33 |
| Jeremy Sowers* |   | sp | 24 | 10 | 2 | 2 | 4 | 3 | 0 | 0 | 5 | 0 | 11.2 | 2.8 | 14.6 | 3.2 | 1.3 | 1.1 | 1.56 |
| Justin Speier | MID | mr | 33 | 2 | 3 | 1 | 4 | 2 | 0 | 2 | 2 | 0 | 6.5 | 2.2 | 9.4 | 8.5 | 1.1 | 3.9 | 0.96 |
| Ryan Speier |   | mr | 27 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 10.0 | 4.0 | 14.5 | 6.5 | 0.5 | 1.6 | 1.56 |
| Levale Speigner |   | mr | 26 | 0 | 1 | 2 | 0 | 1 | 0 | 2 | 3 | 0 | 13.0 | 5.2 | 18.2 | 4.3 | 0.9 | 0.8 | 2.02 |
| Russ Springer | WIZ | mr | 38 | 3 | 3 | 1 | 3 | 1 | 0 | 3 | 6 | 0 | 5.6 | 2.6 | 8.6 | 9.0 | 0.4 | 3.5 | 0.91 |
| Chris Spurling |   | mr | 30 | 2 | 0 | 3 | 2 | 4 | 0 | 0 | 1 | 0 | 11.3 | 2.5 | 14.2 | 5.0 | 1.1 | 2.0 | 1.54 |
| Jason Standridge |   | mr | 28 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 12.9 | 5.9 | 18.8 | 7.0 | 2.3 | 1.2 | 2.09 |
| Jason Stanford* |   | mr | 30 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 10.9 | 2.4 | 14.0 | 5.5 | 0.3 | 2.3 | 1.48 |
| Mike Stanton* |   | mr | 40 | 4 | 1 | 2 | 5 | 1 | 0 | 1 | 1 | 0 | 11.7 | 2.8 | 15.3 | 6.2 | 0.9 | 2.2 | 1.61 |
| Tim Stauffer | MAD | sp | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 17.6 | 7.0 | 25.8 | 7.0 | 5.9 | 1.0 | 2.74 |
| Mitch Stetter* |   | mr | 26 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 3.6 | 3.6 | 10.8 | 7.2 | 0.0 | 2.0 | 0.80 |
| Brian Stokes |   | mr | 27 | 3 | 1 | 1 | 3 | 1 | 0 | 1 | 3 | 0 | 13.0 | 3.6 | 17.0 | 5.1 | 1.6 | 1.4 | 1.84 |
| Ricky Stone |   | mr | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 11.8 | 0.0 | 13.5 | 5.1 | 6.8 | 99.0 | 1.31 |
| Huston Street | GEO | cl | 23 | 5 | 2 | 3 | 0 | 0 | 0 | 2 | 1 | 0 | 6.3 | 2.2 | 8.5 | 11.3 | 0.9 | 5.3 | 0.94 |
| Eric Stults* |   | mr | 27 | 3 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 0 | 11.6 | 4.0 | 15.8 | 7.0 | 1.2 | 1.8 | 1.73 |
| Jeff Suppan |   | sp | 32 | 7 | 0 | 10 | 11 | 7 | 0 | 14 | 11 | 0 | 10.6 | 3.0 | 14.0 | 5.0 | 0.8 | 1.7 | 1.50 |
| Jon Switzer* |   | mr | 27 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 12.8 | 3.3 | 16.1 | 6.2 | 0.9 | 1.9 | 1.79 |
| Brian Tallet* | EDG | mr | 29 | 9 | 1 | 7 | 6 | 1 | 0 | 2 | 3 | 0 | 7.1 | 4.0 | 12.0 | 7.8 | 0.1 | 1.9 | 1.24 |
| Taylor Tankersley* |   | mr | 24 | 1 | 4 | 3 | 3 | 2 | 0 | 0 | 2 | 0 | 8.0 | 5.5 | 14.1 | 9.3 | 0.8 | 1.7 | 1.50 |
| Jack Taschner* |   | mr | 29 | 3 | 0 | 2 | 1 | 2 | 0 | 2 | 3 | 0 | 7.9 | 5.2 | 13.3 | 9.2 | 0.7 | 1.8 | 1.46 |
| Jordan Tata |   | sp | 25 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 10.3 | 5.1 | 16.7 | 5.1 | 0.6 | 1.0 | 1.71 |
| Ty Taubenheim |   | sp | 24 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 9.0 | 7.2 | 18.0 | 7.2 | 1.8 | 1.0 | 1.80 |
| Julian Tavarez |   | sp | 34 | 0 | 0 | 4 | 7 | 4 | 0 | 3 | 5 | 0 | 10.1 | 3.4 | 14.0 | 5.1 | 0.9 | 1.5 | 1.50 |
| Robinson Tejeda |   | sp | 25 | 12 | 5 | 2 | 6 | 10 | 0 | 3 | 6 | 0 | 10.4 | 5.7 | 16.6 | 6.5 | 1.6 | 1.1 | 1.78 |
| Joe Thatcher* |   | mr | 25 | 3 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 5.6 | 2.6 | 8.6 | 6.9 | 0.4 | 2.7 | 0.90 |
| Brad Thompson |   | mr | 25 | 4 | 4 | 2 | 13 | 4 | 0 | 4 | 2 | 0 | 10.9 | 2.8 | 14.6 | 3.7 | 1.6 | 1.3 | 1.52 |
| Mike Thompson |   | mr | 26 | 1 | 0 | 2 | 3 | 0 | 0 | 2 | 3 | 0 | 10.9 | 4.0 | 16.7 | 2.9 | 1.1 | 0.7 | 1.66 |
| Rich Thompson |   | mr | 22 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 13.5 | 4.0 | 17.5 | 12.1 | 5.4 | 3.0 | 1.95 |
| John Thomson |   | sp | 33 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 11.0 | 2.5 | 13.5 | 2.5 | 0.0 | 1.0 | 1.50 |
| Matt Thornton* | CRH | mr | 30 | 1 | 1 | 6 | 2 | 3 | 0 | 0 | 2 | 0 | 9.4 | 4.2 | 13.9 | 8.8 | 0.6 | 2.1 | 1.51 |
| Erick Threets* |   | mr | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 19.3 | 11.6 | 30.9 | 3.9 | 0.0 | 0.3 | 3.43 |
| Mike Timlin | OTR | mr | 41 | 3 | 2 | 3 | 3 | 0 | 0 | 5 | 2 | 0 | 7.5 | 2.3 | 10.2 | 5.0 | 1.1 | 2.2 | 1.08 |
| Brett Tomko |   | mr | 34 | 8 | 5 | 1 | 2 | 5 | 0 | 8 | 6 | 0 | 10.2 | 3.3 | 13.6 | 7.2 | 1.2 | 2.2 | 1.50 |
| Salomon Torres |   | mr | 35 | 2 | 1 | 0 | 4 | 3 | 0 | 1 | 3 | 0 | 9.7 | 2.9 | 13.3 | 7.7 | 1.2 | 2.6 | 1.41 |
| Josh Towers |   | sp | 30 | 13 | 2 | 2 | 6 | 1 | 0 | 3 | 4 | 0 | 10.9 | 1.9 | 13.2 | 6.4 | 1.5 | 3.5 | 1.41 |
| Billy Traber* |   | mr | 27 | 5 | 1 | 3 | 2 | 0 | 0 | 3 | 5 | 0 | 11.3 | 2.9 | 14.7 | 6.1 | 0.9 | 2.1 | 1.59 |
| Steve Trachsel |   | sp | 36 | 19 | 7 | 1 | 2 | 7 | 3 | 5 | 9 | 0 | 10.0 | 4.3 | 14.5 | 3.2 | 1.1 | 0.7 | 1.59 |
| Chin-hui Tsao |   | mr | 26 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.6 | 2.9 | 9.9 | 5.8 | 1.1 | 2.0 | 1.05 |
| Derrick Turnbow | MAD | mr | 29 | 3 | 3 | 0 | 2 | 7 | 0 | 1 | 2 | 0 | 5.8 | 6.1 | 12.2 | 11.1 | 0.5 | 1.8 | 1.32 |
| Lino Urdaneta |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 0.0 | 18.0 | 0.0 | 9.0 | 0.0 | 2.00 |
| Jose Valverde | WIZ | cl | 27 | 4 | 2 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 6.4 | 3.6 | 10.5 | 10.9 | 1.0 | 3.0 | 1.12 |
| John Van Benschoten |   | sp | 27 | 6 | 1 | 1 | 5 | 1 | 0 | 3 | 2 | 0 | 12.7 | 6.7 | 20.5 | 6.0 | 0.9 | 0.9 | 2.15 |
| Rick VandenHurk |   | sp | 22 | 8 | 3 | 5 | 3 | 4 | 4 | 5 | 3 | 0 | 10.4 | 5.3 | 16.0 | 9.0 | 1.7 | 1.7 | 1.74 |
| Claudio Vargas |   | sp | 29 | 11 | 5 | 3 | 2 | 4 | 0 | 5 | 7 | 0 | 10.3 | 3.6 | 14.0 | 7.2 | 1.5 | 2.0 | 1.54 |
| Jason Vargas* |   | sp | 24 | 2 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 14.8 | 1.7 | 16.5 | 3.5 | 3.5 | 2.0 | 1.84 |
| Virgil Vasquez |   | sp | 25 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 14.6 | 2.7 | 17.8 | 3.8 | 3.8 | 1.4 | 1.92 |
| Javier Vazquez | Pal | sp | 30 | 6 | 4 | 2 | 7 | 5 | 0 | 5 | 7 | 0 | 8.2 | 2.1 | 10.6 | 8.8 | 1.2 | 4.3 | 1.14 |
| Jose Veras |   | mr | 26 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 5.8 | 6.8 | 12.5 | 6.8 | 0.0 | 1.0 | 1.39 |
| Justin Verlander | COP | sp | 24 | 4 | 1 | 3 | 19 | 17 | 2 | 3 | 1 | 0 | 8.1 | 3.0 | 11.9 | 8.2 | 0.9 | 2.7 | 1.23 |
| Jamie Vermilyea |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.5 | 0.0 | 7.5 | 3.0 | 0.0 | 99.0 | 0.83 |
| Carlos Villanueva | TON | mr | 23 | 6 | 3 | 3 | 3 | 3 | 0 | 4 | 1 | 0 | 8.0 | 4.2 | 12.4 | 7.8 | 1.3 | 1.9 | 1.35 |
| Oscar Villarreal |   | mr | 25 | 3 | 0 | 8 | 4 | 6 | 0 | 3 | 9 | 0 | 8.8 | 3.8 | 13.1 | 6.8 | 0.7 | 1.8 | 1.40 |
| Ron Villone* |   | mr | 37 | 0 | 0 | 3 | 3 | 4 | 0 | 0 | 1 | 0 | 7.7 | 3.8 | 12.1 | 5.3 | 1.1 | 1.4 | 1.28 |
| Luis Vizcaino | LON | mr | 32 | 5 | 2 | 11 | 2 | 1 | 0 | 2 | 6 | 0 | 7.9 | 5.1 | 13.3 | 7.4 | 0.7 | 1.4 | 1.45 |
| Edinson Volquez |   | sp | 23 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 9.0 | 4.0 | 13.5 | 7.7 | 1.1 | 1.9 | 1.44 |
| Billy Wagner* | BT | cl | 35 | 6 | 0 | 4 | 2 | 4 | 0 | 1 | 2 | 0 | 7.2 | 2.9 | 10.4 | 10.5 | 0.8 | 3.6 | 1.13 |
| Ryan Wagner |   | mr | 24 | 1 | 0 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 11.5 | 4.6 | 16.1 | 5.2 | 1.1 | 1.1 | 1.79 |
| Adam Wainwright | MAD | sp | 25 | 6 | 8 | 4 | 9 | 6 | 0 | 9 | 5 | 0 | 9.4 | 3.1 | 13.0 | 6.1 | 0.6 | 1.9 | 1.40 |
| Tim Wakefield | OTR | sp | 40 | 41 | 8 | 1 | 4 | 10 | 0 | 2 | 6 | 0 | 9.1 | 3.0 | 12.3 | 5.2 | 1.0 | 1.7 | 1.35 |
| Jamie Walker* | OTR | mr | 35 | 2 | 1 | 4 | 2 | 3 | 0 | 0 | 5 | 0 | 8.4 | 2.5 | 11.2 | 6.0 | 0.9 | 2.4 | 1.21 |
| Tyler Walker |   | mr | 31 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 7.5 | 2.5 | 10.0 | 5.7 | 0.0 | 2.3 | 1.12 |
| Chien-Ming Wang | MID | sp | 27 | 14 | 7 | 1 | 8 | 9 | 1 | 2 | 3 | 0 | 9.0 | 2.7 | 12.0 | 4.7 | 0.4 | 1.8 | 1.29 |
| John Wasdin |   | mr | 34 | 0 | 2 | 4 | 0 | 1 | 0 | 0 | 1 | 0 | 14.6 | 3.7 | 18.3 | 4.6 | 0.5 | 1.3 | 2.03 |
| Jarrod Washburn* |   | sp | 32 | 6 | 5 | 5 | 8 | 2 | 1 | 9 | 6 | 0 | 9.3 | 3.1 | 12.8 | 5.3 | 1.1 | 1.7 | 1.38 |
| Ehren Wassermann |   | mr | 26 | 2 | 0 | 4 | 2 | 1 | 0 | 0 | 1 | 0 | 7.8 | 2.7 | 11.3 | 5.5 | 0.0 | 2.0 | 1.17 |
| David Weathers | TON | cl | 37 | 5 | 1 | 4 | 5 | 1 | 0 | 5 | 4 | 0 | 7.8 | 3.1 | 11.5 | 5.6 | 0.5 | 1.8 | 1.21 |
| Jeff Weaver |   | sp | 30 | 9 | 3 | 5 | 8 | 3 | 1 | 4 | 7 | 0 | 11.7 | 2.1 | 14.3 | 4.9 | 1.4 | 2.3 | 1.53 |
| Jered Weaver | OTR | sp | 24 | 19 | 2 | 3 | 2 | 4 | 0 | 5 | 5 | 2 | 10.0 | 2.5 | 12.6 | 6.4 | 1.0 | 2.6 | 1.39 |
| Brandon Webb | TON | sp | 28 | 26 | 9 | 6 | 5 | 3 | 0 | 9 | 6 | 0 | 8.0 | 2.7 | 10.9 | 7.4 | 0.5 | 2.7 | 1.19 |
| Todd Wellemeyer |   | mr | 28 | 4 | 1 | 2 | 3 | 4 | 0 | 3 | 4 | 0 | 8.7 | 4.5 | 13.6 | 6.8 | 1.2 | 1.5 | 1.47 |
| David Wells* |   | sp | 44 | 11 | 7 | 5 | 3 | 1 | 0 | 9 | 4 | 0 | 11.5 | 2.4 | 14.1 | 4.7 | 1.3 | 2.0 | 1.54 |
| Kip Wells |   | sp | 30 | 17 | 5 | 9 | 9 | 8 | 1 | 8 | 7 | 0 | 10.3 | 4.3 | 15.1 | 6.8 | 1.1 | 1.6 | 1.62 |
| Jake Westbrook | MID | sp | 29 | 14 | 7 | 5 | 6 | 3 | 0 | 6 | 4 | 0 | 9.4 | 3.3 | 13.0 | 5.5 | 0.8 | 1.7 | 1.41 |
| Dan Wheeler | Pal | mr | 29 | 4 | 0 | 3 | 3 | 2 | 0 | 3 | 3 | 0 | 8.9 | 2.8 | 12.1 | 9.9 | 1.3 | 3.6 | 1.30 |
| Bill White* |   | mr | 28 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 7.7 | 6.8 | 16.4 | 8.7 | 1.0 | 1.3 | 1.61 |
| Rick White |   | mr | 38 | 0 | 0 | 5 | 0 | 1 | 0 | 2 | 0 | 0 | 12.2 | 4.7 | 16.9 | 4.7 | 1.0 | 1.0 | 1.88 |
| Sean White |   | mr | 26 | 2 | 1 | 0 | 8 | 5 | 1 | 0 | 3 | 0 | 8.9 | 5.1 | 16.0 | 4.1 | 0.5 | 0.8 | 1.56 |
| Bob Wickman |   | cl | 38 | 8 | 0 | 4 | 3 | 3 | 1 | 2 | 1 | 0 | 9.7 | 3.8 | 13.9 | 6.6 | 0.7 | 1.8 | 1.49 |
| Dave Williams* |   | sp | 28 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 24.9 | 10.4 | 35.3 | 4.2 | 4.2 | 0.4 | 3.92 |
| Jerome Williams |   | sp | 25 | 2 | 0 | 0 | 0 | 2 | 1 | 1 | 1 | 0 | 10.2 | 5.4 | 15.6 | 4.5 | 1.8 | 0.8 | 1.73 |
| Todd Williams |   | mr | 36 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 11.9 | 2.5 | 15.1 | 5.7 | 1.3 | 2.3 | 1.60 |
| Woody Williams |   | sp | 40 | 11 | 4 | 5 | 12 | 1 | 2 | 9 | 4 | 0 | 10.3 | 2.5 | 13.5 | 4.8 | 1.7 | 1.9 | 1.43 |
| Scott Williamson |   | mr | 31 | 7 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 7.5 | 5.0 | 12.6 | 10.0 | 0.6 | 2.0 | 1.40 |
| Dontrelle Willis* |   | sp | 25 | 6 | 1 | 4 | 14 | 9 | 1 | 15 | 7 | 0 | 10.6 | 3.8 | 15.0 | 6.4 | 1.3 | 1.7 | 1.60 |
| Brian Wilson |   | cl | 25 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.1 | 2.7 | 9.1 | 6.8 | 0.4 | 2.6 | 0.97 |
| C.J. Wilson* | ROK | mr | 26 | 2 | 0 | 1 | 6 | 5 | 0 | 2 | 4 | 0 | 6.6 | 4.3 | 11.7 | 8.3 | 0.5 | 1.9 | 1.21 |
| Matt Wise |   | mr | 31 | 9 | 0 | 1 | 1 | 0 | 1 | 1 | 3 | 0 | 10.2 | 2.9 | 13.2 | 7.2 | 0.8 | 2.5 | 1.45 |
| Jay Witasick |   | mr | 34 | 1 | 1 | 2 | 1 | 4 | 0 | 1 | 1 | 0 | 8.9 | 7.8 | 16.9 | 5.2 | 0.6 | 0.7 | 1.85 |
| Randy Wolf* | CCL | sp | 30 | 4 | 3 | 2 | 6 | 4 | 0 | 5 | 5 | 0 | 9.6 | 3.4 | 13.6 | 8.2 | 0.9 | 2.4 | 1.45 |
| Ross Wolf |   | mr | 24 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 17.5 | 2.2 | 20.4 | 4.4 | 2.9 | 2.0 | 2.19 |
| Brian Wolfe | OTR | mr | 26 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 0 | 7.1 | 1.8 | 9.3 | 4.4 | 1.0 | 2.4 | 0.99 |
| Kerry Wood | MUL | mr | 30 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 6.7 | 4.8 | 11.5 | 8.9 | 0.0 | 1.8 | 1.27 |
| Mike Wood |   | mr | 27 | 1 | 1 | 1 | 4 | 3 | 0 | 1 | 2 | 0 | 12.1 | 2.7 | 15.5 | 4.4 | 1.6 | 1.7 | 1.64 |
| Jake Woods* |   | mr | 25 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.6 | 5.9 | 14.3 | 3.4 | 0.8 | 0.6 | 1.50 |
| Chase Wright* |   | sp | 24 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 10.8 | 5.4 | 18.0 | 7.2 | 4.5 | 1.3 | 1.80 |
| Jamey Wright |   | mr | 32 | 4 | 4 | 2 | 5 | 4 | 0 | 3 | 2 | 1 | 8.4 | 4.8 | 13.8 | 4.6 | 0.7 | 1.0 | 1.47 |
| Jaret Wright |   | sp | 31 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.5 | 7.8 | 18.3 | 6.1 | 0.9 | 0.8 | 2.03 |
| Michael Wuertz | BT | mr | 28 | 7 | 1 | 6 | 0 | 6 | 0 | 3 | 1 | 0 | 8.0 | 4.4 | 12.3 | 9.8 | 1.0 | 2.3 | 1.37 |
| Tyler Yates |   | mr | 29 | 7 | 1 | 8 | 3 | 2 | 0 | 4 | 1 | 0 | 8.7 | 4.2 | 13.4 | 9.4 | 0.8 | 2.2 | 1.44 |
| Shane Youman* |   | sp | 27 | 4 | 1 | 1 | 4 | 2 | 0 | 10 | 2 | 0 | 10.2 | 3.6 | 14.4 | 4.6 | 0.8 | 1.3 | 1.53 |
| Chris Young | COP | sp | 28 | 44 | 0 | 0 | 7 | 7 | 4 | 3 | 6 | 1 | 6.1 | 3.7 | 10.2 | 8.7 | 0.5 | 2.3 | 1.10 |
| Mike Zagurski* |   | mr | 24 | 0 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 0 | 10.5 | 4.6 | 15.6 | 8.9 | 1.3 | 1.9 | 1.69 |
| Carlos Zambrano | CCL | sp | 26 | 4 | 3 | 4 | 14 | 3 | 0 | 6 | 3 | 0 | 7.8 | 4.2 | 12.6 | 7.4 | 1.0 | 1.8 | 1.33 |
| Victor Zambrano |   | mr | 31 | 2 | 1 | 2 | 5 | 2 | 0 | 2 | 2 | 0 | 12.5 | 8.6 | 23.1 | 6.3 | 2.3 | 0.7 | 2.35 |
| Mauro Zarate |   | mr | 24 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 19.8 | 1.8 | 23.4 | 5.4 | 5.4 | 3.0 | 2.40 |
| Barry Zito* | EDG | sp | 29 | 5 | 1 | 4 | 4 | 5 | 0 | 12 | 4 | 0 | 8.3 | 3.8 | 12.3 | 6.0 | 1.1 | 1.6 | 1.35 |
| Joel Zumaya |   | mr | 22 | 3 | 0 | 2 | 1 | 3 | 0 | 1 | 1 | 0 | 6.1 | 4.5 | 11.0 | 7.2 | 0.8 | 1.6 | 1.19 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | BT | mr | 25 | .867 | 93 | .376 | 80 | .530 | 81 | .536 | 25.4 | 7.2 | 6.36 | 5.93 |
| Winston Abreu |   | mr | 30 | .889 | 91 | .330 | 75 | .564 | 75 | .564 | 21.9 | 6.4 | 5.86 | 5.90 |
| Jeremy Accardo | CRH | cl | 25 | .558 | 188 | .250 | 93 | .338 | 95 | .345 | 21.5 | 2.9 | 2.59 | 2.44 |
| Manny Acosta |   | mr | 26 | .543 | 55 | .200 | 34 | .366 | 34 | .366 | 6.0 | 2.3 | 2.06 | 2.39 |
| Jon Adkins |   | mr | 29 | .000 | 3 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Jeremy Affeldt* | CRH | mr | 28 | .707 | 168 | .262 | 111 | .439 | 114 | .451 | 27.7 | 4.2 | 3.80 | 3.19 |
| Jonathan Albaladejo |   | mr | 24 | .451 | 35 | .171 | 14 | .275 | 15 | .294 | 2.2 | 1.4 | 1.23 | 1.10 |
| Matt Albers |   | sp | 24 | .859 | 362 | .301 | 265 | .522 | 272 | .535 | 81.2 | 6.5 | 5.94 | 5.76 |
| Antonio Alfonseca |   | mr | 35 | .843 | 181 | .343 | 120 | .508 | 121 | .513 | 39.2 | 7.3 | 6.40 | 6.03 |
| Greg Aquino |   | mr | 29 | .744 | 40 | .275 | 28 | .475 | 28 | .475 | 7.1 | 4.5 | 4.09 | 3.69 |
| Alberto Arias |   | mr | 23 | .958 | 23 | .304 | 19 | .594 | 19 | .594 | 5.4 | 7.0 | 6.01 | 6.51 |
| Tony Armas |   | mr | 29 | .845 | 305 | .305 | 227 | .514 | 235 | .532 | 71.5 | 6.6 | 5.97 | 5.77 |
| Bronson Arroyo | BT | sp | 30 | .789 | 661 | .309 | 436 | .473 | 449 | .488 | 126.5 | 5.4 | 4.86 | 4.68 |
| Jose Ascanio |   | mr | 22 | .808 | 52 | .269 | 39 | .527 | 39 | .527 | 10.7 | 5.7 | 5.44 | 4.43 |
| Scott Atchison |   | mr | 31 | .792 | 90 | .300 | 64 | .489 | 65 | .496 | 18.5 | 5.5 | 4.88 | 4.65 |
| Luis Ayala |   | mr | 29 | .712 | 135 | .281 | 76 | .420 | 77 | .425 | 20.6 | 4.3 | 3.93 | 3.88 |
| Brandon Backe |   | sp | 29 | .747 | 95 | .242 | 57 | .463 | 59 | .480 | 15.4 | 4.9 | 4.36 | 4.26 |
| Mike Bacsik* |   | sp | 29 | .853 | 414 | .278 | 274 | .527 | 280 | .538 | 79.4 | 6.0 | 5.45 | 5.61 |
| Cha Seung Baek | EDG | sp | 27 | .769 | 249 | .325 | 148 | .461 | 151 | .470 | 43.1 | 5.2 | 4.76 | 4.24 |
| Danys Baez |   | mr | 29 | .820 | 160 | .262 | 115 | .494 | 122 | .524 | 34.1 | 6.0 | 5.48 | 5.56 |
| Homer Bailey | CCL | sp | 21 | .758 | 143 | .280 | 94 | .459 | 97 | .473 | 27.2 | 5.4 | 4.87 | 4.61 |
| Scott Baker | BON | sp | 25 | .763 | 455 | .323 | 275 | .454 | 280 | .462 | 76.1 | 4.8 | 4.29 | 4.19 |
| John Bale* | BON | mr | 33 | .719 | 118 | .373 | 73 | .408 | 74 | .413 | 21.2 | 4.8 | 4.30 | 4.32 |
| Grant Balfour |   | mr | 29 | .913 | 68 | .412 | 66 | .545 | 67 | .554 | 22.1 | 8.2 | 7.25 | 7.15 |
| Josh Banks |   | mr | 24 | .903 | 30 | .333 | 19 | .543 | 19 | .543 | 6.7 | 8.2 | 7.40 | 6.66 |
| Brian Bannister | EDG | sp | 26 | .712 | 541 | .261 | 300 | .439 | 306 | .448 | 75.5 | 4.1 | 3.71 | 3.36 |
| Daniel Barone |   | mr | 24 | .954 | 134 | .291 | 111 | .607 | 112 | .612 | 33.3 | 7.4 | 6.58 | 7.23 |
| Kevin Barry |   | mr | 28 | 1.238 | 8 | .750 | 10 | .714 | 10 | .714 | 4.9 | 21.9 | 19.72 | 19.55 |
| Miguel Batista |   | sp | 36 | .773 | 616 | .310 | 403 | .469 | 411 | .478 | 113.2 | 5.2 | 4.75 | 4.81 |
| Denny Bautista |   | mr | 26 | .989 | 35 | .514 | 25 | .521 | 26 | .542 | 10.7 | 11.1 | 10.00 | 10.84 |
| Jonah Bayliss |   | mr | 26 | .960 | 122 | .352 | 107 | .598 | 109 | .609 | 36.0 | 8.7 | 7.75 | 7.65 |
| Yorman Bazardo |   | mr | 22 | .638 | 71 | .239 | 36 | .375 | 39 | .406 | 8.2 | 3.0 | 2.80 | 2.71 |
| Colter Bean |   | mr | 30 | 1.026 | 12 | .417 | 12 | .632 | 12 | .632 | 4.6 | 13.9 | 12.53 | 12.68 |
| Josh Beckett | Pal | sp | 27 | .663 | 566 | .304 | 331 | .403 | 336 | .409 | 82.1 | 3.7 | 3.32 | 2.99 |
| Erik Bedard* | GEO | sp | 28 | .615 | 431 | .283 | 281 | .383 | 286 | .390 | 63.1 | 3.1 | 2.81 | 2.71 |
| Joe Beimel* | WIZ | mr | 30 | .648 | 216 | .287 | 106 | .377 | 107 | .381 | 24.1 | 3.1 | 2.90 | 2.93 |
| Matt Belisle | CCL | sp | 27 | .825 | 570 | .326 | 383 | .497 | 390 | .506 | 114.4 | 5.8 | 5.22 | 5.05 |
| Heath Bell | MUL | mr | 29 | .503 | 226 | .252 | 110 | .303 | 112 | .309 | 21.0 | 2.0 | 1.81 | 1.67 |
| Rob Bell |   | mr | 30 | .890 | 192 | .344 | 136 | .542 | 136 | .542 | 45.3 | 7.7 | 6.93 | 6.61 |
| Armando Benitez |   | mr | 34 | .811 | 133 | .308 | 116 | .509 | 117 | .513 | 33.2 | 5.9 | 5.35 | 5.01 |
| Jeff Bennett |   | sp | 27 | .784 | 37 | .297 | 28 | .491 | 28 | .491 | 7.9 | 5.3 | 4.94 | 4.41 |
| Joaquin Benoit | OTR | mr | 29 | .641 | 214 | .290 | 133 | .395 | 135 | .401 | 31.3 | 3.4 | 3.09 | 2.83 |
| Jason Bergmann |   | sp | 25 | .728 | 332 | .244 | 225 | .469 | 227 | .473 | 56.0 | 4.4 | 3.93 | 3.59 |
| Rafael Betancourt | GEO | mr | 32 | .485 | 196 | .240 | 86 | .298 | 86 | .298 | 15.0 | 1.7 | 1.53 | 1.24 |
| Chad Billingsley | TON | mr | 22 | .701 | 400 | .290 | 270 | .433 | 273 | .438 | 66.1 | 4.0 | 3.64 | 3.70 |
| Kurt Birkins* |   | mr | 26 | .903 | 120 | .408 | 90 | .529 | 93 | .547 | 31.9 | 8.4 | 7.53 | 7.41 |
| Joe Bisenius |   | mr | 24 | .873 | 4 | .500 | 5 | .556 | 5 | .556 | 1.6 | 8.4 | 6.34 | 6.15 |
| Nick Blackburn |   | mr | 25 | .908 | 42 | .405 | 29 | .537 | 29 | .537 | 9.2 | 6.9 | 6.37 | 7.61 |
| Travis Blackley* |   | sp | 24 | .973 | 28 | .286 | 25 | .625 | 25 | .625 | 7.6 | 7.9 | 7.14 | 6.78 |
| Joe Blanton | BON | sp | 26 | .679 | 750 | .299 | 378 | .398 | 382 | .402 | 99.1 | 3.9 | 3.49 | 3.30 |
| Jerry Blevins* |   | mr | 23 | .965 | 19 | .368 | 15 | .600 | 15 | .600 | 5.4 | 9.7 | 9.39 | 9.08 |
| Jeremy Bonderman |   | sp | 24 | .779 | 533 | .319 | 363 | .482 | 367 | .487 | 101.6 | 5.2 | 4.72 | 4.44 |
| Boof Bonser |   | sp | 25 | .819 | 539 | .319 | 391 | .506 | 396 | .513 | 114.2 | 5.9 | 5.34 | 5.33 |
| Chris Booker |   | mr | 30 | 1.733 | 2 | .000 | 5 | 1.000 | 5 | 1.000 | 1.9 | 17.2 | 15.49 | 14.27 |
| Chris Bootcheck |   | mr | 28 | .757 | 239 | .310 | 149 | .450 | 154 | .465 | 41.3 | 4.8 | 4.32 | 4.16 |
| Dave Borkowski |   | mr | 30 | .796 | 216 | .315 | 157 | .483 | 161 | .495 | 46.1 | 5.8 | 5.21 | 4.76 |
| Joe Borowski | EDG | cl | 36 | .768 | 206 | .330 | 133 | .455 | 135 | .462 | 40.8 | 5.5 | 5.04 | 4.68 |
| Micah Bowie* |   | mr | 32 | .738 | 170 | .282 | 110 | .444 | 112 | .452 | 28.7 | 4.5 | 4.06 | 4.48 |
| Blaine Boyer |   | mr | 25 | .898 | 22 | .455 | 12 | .462 | 12 | .462 | 5.1 | 9.2 | 7.74 | 7.41 |
| Dallas Braden* |   | sp | 23 | .839 | 240 | .342 | 169 | .509 | 171 | .515 | 52.6 | 6.5 | 5.89 | 5.63 |
| Chad Bradford | MID | mr | 32 | .687 | 237 | .321 | 105 | .363 | 111 | .384 | 31.1 | 4.2 | 3.89 | 4.16 |
| Ryan Braun |   | mr | 26 | .843 | 133 | .316 | 94 | .514 | 94 | .514 | 28.5 | 6.4 | 5.86 | 5.64 |
| Bill Bray* |   | mr | 24 | .789 | 43 | .349 | 31 | .492 | 31 | .492 | 8.9 | 5.6 | 5.04 | 4.16 |
| Yhency Brazoban |   | mr | 27 | 1.056 | 4 | .750 | 8 | .667 | 8 | .667 | 3.0 | 13.6 | 14.68 | 11.51 |
| Chris Britton |   | mr | 24 | .630 | 40 | .175 | 21 | .412 | 21 | .412 | 4.9 | 3.5 | 3.11 | 2.55 |
| Lance Broadway |   | mr | 23 | .444 | 22 | .227 | 12 | .293 | 12 | .293 | 1.9 | 1.6 | 1.52 | 1.34 |
| Doug Brocail | CCL | mr | 40 | .652 | 242 | .240 | 129 | .404 | 131 | .411 | 31.1 | 3.6 | 3.29 | 3.03 |
| Jim Brower |   | mr | 34 | 1.211 | 17 | .471 | 13 | .619 | 14 | .667 | 6.6 | 16.2 | 16.04 | 14.45 |
| Andrew Brown | EDG | mr | 26 | .691 | 114 | .325 | 73 | .410 | 76 | .427 | 20.0 | 4.4 | 3.89 | 3.27 |
| Jonathan Broxton | CCL | mr | 23 | .617 | 203 | .310 | 127 | .380 | 128 | .383 | 28.4 | 3.1 | 2.81 | 2.71 |
| Brian Bruney |   | mr | 25 | .757 | 144 | .271 | 107 | .469 | 110 | .482 | 27.8 | 4.9 | 4.50 | 4.92 |
| Clay Buchholz |   | sp | 22 | .508 | 55 | .255 | 27 | .307 | 28 | .318 | 5.1 | 2.1 | 1.82 | 1.90 |
| Taylor Buchholz | TON | mr | 25 | .748 | 305 | .318 | 174 | .439 | 176 | .444 | 49.1 | 4.7 | 4.24 | 3.97 |
| Billy Buckner |   | sp | 23 | .887 | 105 | .305 | 81 | .566 | 81 | .566 | 21.6 | 5.9 | 5.15 | 5.57 |
| Mark Buehrle* | GEO | sp | 28 | .728 | 648 | .287 | 367 | .440 | 372 | .446 | 96.0 | 4.3 | 3.87 | 3.75 |
| Ryan Bukvich |   | mr | 29 | .801 | 120 | .258 | 84 | .494 | 87 | .512 | 23.9 | 5.8 | 5.43 | 5.70 |
| Jason Bulger |   | mr | 28 | .547 | 14 | .357 | 8 | .320 | 8 | .320 | 1.6 | 2.4 | 2.07 | 2.74 |
| Bryan Bullington |   | sp | 26 | .901 | 61 | .344 | 41 | .539 | 41 | .539 | 13.3 | 7.2 | 6.33 | 6.90 |
| Ambiorix Burgos |   | mr | 23 | .653 | 65 | .215 | 40 | .408 | 42 | .429 | 9.8 | 3.7 | 3.34 | 2.97 |
| A.J. Burnett | TON | sp | 30 | .664 | 414 | .261 | 287 | .415 | 299 | .433 | 70.9 | 3.8 | 3.47 | 3.47 |
| Brian Burres* |   | mr | 26 | .813 | 378 | .333 | 277 | .496 | 282 | .504 | 83.2 | 6.2 | 5.57 | 5.89 |
| Jared Burton | MAD | mr | 26 | .550 | 114 | .228 | 60 | .341 | 62 | .352 | 12.1 | 2.5 | 2.28 | 2.37 |
| Dave Bush | OTR | sp | 27 | .815 | 594 | .320 | 400 | .494 | 411 | .507 | 118.8 | 5.8 | 5.17 | 4.93 |
| Paul Byrd |   | sp | 36 | .801 | 686 | .309 | 403 | .483 | 409 | .490 | 120.9 | 5.6 | 5.09 | 4.80 |
| Tim Byrdak* | EDG | mr | 33 | .700 | 120 | .292 | 87 | .437 | 88 | .442 | 21.6 | 4.2 | 3.89 | 3.53 |
| Daniel Cabrera |   | sp | 26 | .777 | 608 | .299 | 431 | .467 | 446 | .484 | 124.1 | 5.4 | 4.92 | 5.08 |
| Fernando Cabrera |   | mr | 25 | .914 | 119 | .345 | 122 | .589 | 122 | .589 | 37.2 | 7.7 | 6.91 | 6.98 |
| Matt Cain | LON | sp | 22 | .678 | 571 | .278 | 348 | .418 | 353 | .424 | 85.4 | 3.9 | 3.46 | 3.23 |
| Kiko Calero |   | mr | 32 | .819 | 128 | .336 | 91 | .492 | 93 | .503 | 29.3 | 6.7 | 5.84 | 5.26 |
| Carmen Cali* |   | mr | 28 | .794 | 67 | .299 | 49 | .485 | 51 | .505 | 14.2 | 6.2 | 5.50 | 5.87 |
| Kevin Cameron | LON | mr | 27 | .623 | 177 | .311 | 96 | .365 | 96 | .365 | 24.8 | 3.8 | 3.46 | 3.67 |
| Shawn Camp |   | mr | 31 | .991 | 134 | .418 | 113 | .571 | 116 | .586 | 39.0 | 8.6 | 7.91 | 8.59 |
| Jorge Campillo |   | mr | 28 | 1.014 | 45 | .356 | 39 | .619 | 40 | .635 | 12.9 | 8.5 | 7.83 | 7.18 |
| Jose Capellan |   | mr | 26 | .859 | 78 | .269 | 64 | .557 | 65 | .565 | 19.0 | 6.6 | 5.93 | 5.49 |
| Matt Capps | MUL | mr | 23 | .582 | 227 | .260 | 108 | .343 | 111 | .352 | 24.4 | 2.8 | 2.51 | 2.10 |
| Chris Capuano* |   | sp | 28 | .803 | 455 | .330 | 322 | .481 | 330 | .493 | 95.6 | 5.7 | 5.16 | 5.11 |
| Buddy Carlyle |   | sp | 29 | .857 | 335 | .293 | 247 | .535 | 249 | .539 | 69.3 | 5.8 | 5.25 | 4.71 |
| Fausto Carmona | GEO | sp | 23 | .661 | 654 | .280 | 343 | .390 | 354 | .403 | 82.5 | 3.5 | 3.11 | 3.32 |
| Chris Carpenter | CRH | sp | 32 | .777 | 24 | .375 | 11 | .379 | 12 | .414 | 4.2 | 6.3 | 5.65 | 5.80 |
| Hector Carrasco |   | mr | 37 | .870 | 122 | .295 | 105 | .561 | 106 | .567 | 31.2 | 7.0 | 6.60 | 6.40 |
| Marcos Carvajal |   | mr | 22 | .845 | 20 | .400 | 11 | .458 | 11 | .458 | 4.4 | 8.5 | 8.91 | 8.87 |
| Santiago Casilla | OTR | mr | 26 | .676 | 137 | .270 | 94 | .429 | 95 | .434 | 24.7 | 4.4 | 3.95 | 3.39 |
| Jack Cassel |   | sp | 26 | .780 | 80 | .363 | 43 | .439 | 44 | .449 | 12.9 | 5.3 | 4.62 | 5.17 |
| Fabio Castro* |   | mr | 22 | .788 | 27 | .259 | 30 | .536 | 30 | .536 | 7.3 | 5.5 | 4.91 | 5.99 |
| Troy Cate* |   | mr | 26 | .741 | 52 | .327 | 32 | .432 | 32 | .432 | 9.5 | 5.3 | 4.78 | 5.10 |
| Andy Cavazos |   | mr | 26 | 1.071 | 66 | .333 | 67 | .644 | 69 | .663 | 24.1 | 10.7 | 9.76 | 9.65 |
| Gustavo Chacin* |   | sp | 26 | .827 | 92 | .250 | 62 | .525 | 64 | .542 | 17.4 | 5.7 | 5.16 | 4.90 |
| Shawn Chacon |   | mr | 29 | .771 | 285 | .302 | 196 | .458 | 203 | .474 | 54.9 | 5.1 | 4.63 | 4.46 |
| Joba Chamberlain |   | mr | 21 | .440 | 49 | .224 | 25 | .275 | 26 | .286 | 4.3 | 1.6 | 1.46 | 1.16 |
| Bruce Chen* |   | mr | 30 | .970 | 30 | .267 | 30 | .652 | 30 | .652 | 8.3 | 7.2 | 6.68 | 6.90 |
| Rocky Cherry |   | mr | 27 | .801 | 96 | .271 | 71 | .490 | 74 | .510 | 20.6 | 5.9 | 5.33 | 5.05 |
| Matt Chico* |   | sp | 24 | .824 | 548 | .286 | 381 | .510 | 386 | .517 | 111.0 | 6.0 | 5.38 | 5.31 |
| Randy Choate* |   | mr | 31 | 2.000 | 3 | 1.000 | 3 | 1.000 | 3 | 1.000 | 3.0 | 0.0 | 99.00 | 0.00 |
| Vinnie Chulk |   | mr | 28 | .710 | 162 | .309 | 94 | .423 | 96 | .432 | 25.2 | 4.3 | 3.85 | 3.37 |
| Darren Clarke |   | mr | 26 | .762 | 5 | .400 | 3 | .429 | 3 | .429 | 1.0 | 6.5 | 5.88 | 7.52 |
| Roger Clemens | ROK | sp | 44 | .716 | 307 | .293 | 180 | .429 | 185 | .440 | 49.0 | 4.4 | 4.01 | 3.90 |
| Tyler Clippard |   | sp | 22 | .876 | 83 | .277 | 71 | .573 | 71 | .573 | 21.6 | 7.3 | 6.47 | 6.37 |
| Todd Coffey |   | mr | 26 | .897 | 163 | .356 | 129 | .533 | 134 | .554 | 41.3 | 7.0 | 6.55 | 7.58 |
| Willie Collazo* |   | mr | 27 | .854 | 22 | .318 | 14 | .519 | 14 | .519 | 3.7 | 5.9 | 5.32 | 6.54 |
| Jesus Colome |   | mr | 29 | .709 | 209 | .278 | 122 | .427 | 123 | .430 | 32.9 | 4.5 | 4.04 | 3.83 |
| Bartolo Colon |   | sp | 34 | .860 | 328 | .357 | 231 | .510 | 236 | .521 | 73.2 | 6.6 | 5.97 | 6.17 |
| Steve Colyer* |   | mr | 28 | 1.313 | 13 | .615 | 17 | .773 | 17 | .773 | 7.0 | 17.2 | 15.51 | 20.81 |
| Clay Condrey |   | mr | 31 | .790 | 176 | .324 | 103 | .452 | 108 | .474 | 31.4 | 5.6 | 5.09 | 5.14 |
| Jose Contreras |   | sp | 35 | .814 | 647 | .326 | 406 | .473 | 421 | .491 | 127.8 | 6.0 | 5.48 | 5.49 |
| Aaron Cook | MAD | sp | 28 | .744 | 572 | .285 | 309 | .443 | 315 | .451 | 81.3 | 4.4 | 3.97 | 4.05 |
| Tim Corcoran |   | mr | 29 | .804 | 58 | .259 | 40 | .506 | 41 | .519 | 10.1 | 5.1 | 4.71 | 5.25 |
| Chad Cordero |   | cl | 25 | .731 | 222 | .302 | 146 | .455 | 146 | .455 | 37.4 | 4.5 | 4.04 | 4.02 |
| Francisco Cordero | CRH | cl | 32 | .588 | 152 | .316 | 93 | .356 | 94 | .360 | 21.9 | 3.1 | 2.80 | 2.45 |
| Bryan Corey |   | mr | 33 | .630 | 22 | .273 | 12 | .375 | 12 | .375 | 2.0 | 2.1 | 1.72 | 2.13 |
| Lance Cormier |   | sp | 26 | 1.009 | 145 | .276 | 139 | .662 | 139 | .662 | 43.1 | 8.4 | 7.64 | 7.66 |
| Rheal Cormier* |   | mr | 40 | 1.189 | 10 | .300 | 9 | .643 | 10 | .714 | 3.2 | 9.7 | 8.72 | 9.77 |
| Manny Corpas | MUL | mr | 24 | .596 | 220 | .259 | 109 | .356 | 111 | .363 | 22.2 | 2.5 | 2.30 | 2.51 |
| Kevin Correia | MUL | mr | 26 | .688 | 306 | .278 | 185 | .423 | 187 | .428 | 48.1 | 4.2 | 3.83 | 3.48 |
| Neal Cotts* |   | mr | 27 | .737 | 49 | .286 | 32 | .421 | 35 | .461 | 8.2 | 4.1 | 3.97 | 4.41 |
| Jon Coutlangus* |   | mr | 26 | .735 | 115 | .304 | 82 | .439 | 86 | .460 | 22.1 | 4.8 | 4.37 | 4.88 |
| Jesse Crain |   | mr | 25 | .876 | 52 | .288 | 39 | .549 | 40 | .563 | 10.9 | 5.9 | 5.40 | 5.73 |
| Juan Cruz | TON | mr | 28 | .680 | 131 | .290 | 112 | .427 | 117 | .447 | 27.5 | 4.1 | 3.65 | 3.43 |
| John Danks* | EDG | sp | 22 | .868 | 427 | .309 | 338 | .543 | 342 | .550 | 101.8 | 6.6 | 5.93 | 5.73 |
| Dave Davidson* |   | mr | 23 | 1.434 | 12 | .417 | 13 | .765 | 15 | .882 | 7.1 | 27.3 | 28.68 | 29.58 |
| Kyle Davies |   | sp | 23 | .863 | 432 | .308 | 339 | .540 | 344 | .548 | 103.8 | 6.8 | 6.18 | 5.90 |
| Doug Davis* |   | sp | 31 | .794 | 597 | .318 | 417 | .484 | 422 | .490 | 116.3 | 5.4 | 4.89 | 5.15 |
| Jason Davis |   | mr | 27 | .810 | 127 | .299 | 86 | .486 | 88 | .497 | 24.7 | 5.8 | 5.42 | 6.14 |
| Kane Davis |   | mr | 32 | .964 | 39 | .385 | 35 | .593 | 35 | .593 | 11.0 | 8.1 | 7.89 | 8.60 |
| Dewon Day |   | mr | 26 | .980 | 46 | .391 | 37 | .569 | 39 | .600 | 13.5 | 9.9 | 9.12 | 9.76 |
| Jordan De Jong |   | mr | 28 | .813 | 30 | .367 | 21 | .500 | 21 | .500 | 6.3 | 6.1 | 5.66 | 5.19 |
| Eulogio De La Cruz |   | mr | 23 | .973 | 22 | .409 | 19 | .594 | 19 | .594 | 5.9 | 8.0 | 7.19 | 8.47 |
| Jorge De La Rosa* |   | sp | 26 | .873 | 431 | .325 | 319 | .542 | 322 | .547 | 96.4 | 6.7 | 6.00 | 5.93 |
| Manny Delcarmen | GEO | mr | 25 | .564 | 112 | .214 | 62 | .352 | 64 | .364 | 13.2 | 2.7 | 2.43 | 2.23 |
| Ryan Dempster | CRH | cl | 30 | .717 | 188 | .271 | 127 | .450 | 128 | .454 | 33.2 | 4.5 | 4.03 | 3.77 |
| Julio DePaula |   | mr | 24 | 1.046 | 73 | .342 | 61 | .616 | 64 | .646 | 21.7 | 9.8 | 8.80 | 9.69 |
| Matt DeSalvo |   | sp | 26 | .887 | 102 | .314 | 71 | .526 | 74 | .548 | 23.2 | 7.6 | 6.80 | 6.68 |
| Elmer Dessens |   | mr | 36 | .923 | 116 | .336 | 90 | .577 | 90 | .577 | 28.8 | 7.6 | 6.86 | 6.37 |
| Ross Detwiler* |   | mr | 21 | .000 | 3 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Joey Devine |   | mr | 23 | .636 | 24 | .292 | 15 | .385 | 15 | .385 | 3.4 | 3.7 | 3.35 | 4.08 |
| Lenny DiNardo* |   | sp | 27 | .750 | 430 | .286 | 248 | .447 | 251 | .452 | 62.9 | 4.3 | 3.88 | 4.39 |
| Scott Dohmann |   | mr | 29 | .749 | 89 | .292 | 63 | .463 | 63 | .463 | 16.2 | 4.6 | 4.01 | 4.13 |
| Brendan Donnelly |   | mr | 35 | .620 | 66 | .288 | 30 | .333 | 34 | .378 | 8.8 | 3.8 | 3.46 | 3.00 |
| Octavio Dotel |   | cl | 33 | .748 | 77 | .325 | 62 | .449 | 66 | .478 | 17.6 | 5.1 | 4.64 | 4.12 |
| Dennis Dove |   | mr | 25 | 1.257 | 11 | .273 | 13 | .867 | 13 | .867 | 4.9 | 14.7 | 13.24 | 12.68 |
| Scott Downs* | EDG | mr | 31 | .592 | 154 | .286 | 85 | .356 | 86 | .360 | 18.6 | 2.9 | 2.59 | 2.81 |
| Cory Doyne |   | mr | 25 | 1.147 | 15 | .400 | 14 | .636 | 15 | .682 | 6.3 | 15.4 | 13.87 | 14.78 |
| Travis Driskill |   | mr | 35 | .972 | 23 | .391 | 17 | .586 | 17 | .586 | 6.0 | 8.5 | 8.05 | 7.50 |
| Justin Duchscherer | COP | mr | 29 | .914 | 51 | .294 | 44 | .587 | 44 | .587 | 14.0 | 7.7 | 6.95 | 5.22 |
| Brandon Duckworth |   | mr | 31 | .757 | 163 | .294 | 97 | .460 | 98 | .464 | 27.0 | 5.2 | 4.68 | 4.69 |
| Zach Duke* |   | sp | 24 | .941 | 399 | .368 | 270 | .560 | 273 | .566 | 86.0 | 7.2 | 6.49 | 6.96 |
| Phil Dumatrait* |   | sp | 25 | 1.291 | 76 | .434 | 80 | .769 | 81 | .779 | 36.0 | 18.4 | 16.21 | 15.81 |
| Chad Durbin |   | sp | 29 | .781 | 417 | .269 | 268 | .478 | 276 | .492 | 76.0 | 5.4 | 4.82 | 4.92 |
| J.D. Durbin |   | sp | 25 | .829 | 220 | .327 | 152 | .498 | 154 | .505 | 45.8 | 6.3 | 5.68 | 5.85 |
| Adam Eaton |   | sp | 29 | .898 | 525 | .309 | 402 | .548 | 413 | .563 | 123.9 | 6.9 | 6.21 | 6.33 |
| Scott Elarton |   | sp | 31 | 1.087 | 136 | .301 | 126 | .681 | 129 | .697 | 43.9 | 10.5 | 9.62 | 9.76 |
| Alan Embree* | BON | cl | 37 | .681 | 209 | .297 | 117 | .412 | 117 | .412 | 30.3 | 4.0 | 3.61 | 3.24 |
| John Ennis |   | cl | 27 | .880 | 26 | .423 | 20 | .526 | 20 | .526 | 7.2 | 8.5 | 7.63 | 7.56 |
| Kelvim Escobar | BON | sp | 31 | .669 | 572 | .299 | 329 | .405 | 332 | .409 | 79.6 | 3.6 | 3.30 | 3.25 |
| Dana Eveland* |   | mr | 23 | .964 | 20 | .400 | 16 | .571 | 16 | .571 | 6.2 | 11.1 | 10.03 | 9.25 |
| Scott Eyre* |   | mr | 35 | .832 | 156 | .359 | 122 | .508 | 123 | .512 | 35.7 | 6.2 | 5.52 | 5.61 |
| Willie Eyre |   | mr | 28 | .819 | 224 | .313 | 153 | .498 | 154 | .502 | 45.0 | 6.0 | 5.35 | 5.32 |
| Brian Falkenborg |   | mr | 29 | .809 | 57 | .351 | 41 | .488 | 42 | .500 | 12.0 | 5.8 | 5.19 | 5.58 |
| Kyle Farnsworth |   | mr | 31 | .750 | 180 | .283 | 124 | .466 | 126 | .474 | 35.6 | 5.3 | 4.81 | 4.67 |
| Ryan Feierabend* |   | sp | 21 | 1.018 | 172 | .366 | 146 | .619 | 150 | .636 | 52.0 | 9.9 | 8.54 | 8.71 |
| Scott Feldman | MID | mr | 24 | .831 | 135 | .304 | 97 | .505 | 100 | .521 | 29.3 | 6.6 | 6.08 | 6.40 |
| Pedro Feliciano* | MAD | mr | 30 | .610 | 175 | .251 | 103 | .375 | 108 | .393 | 22.9 | 3.1 | 2.90 | 2.74 |
| Nate Field |   | mr | 31 | 1.238 | 4 | .750 | 5 | .714 | 5 | .714 | 2.4 | 21.9 | 19.72 | 19.55 |
| Randy Flores* |   | mr | 31 | .772 | 186 | .371 | 110 | .435 | 113 | .447 | 34.5 | 5.5 | 5.08 | 4.87 |
| Ron Flores* |   | mr | 27 | .772 | 52 | .269 | 41 | .506 | 41 | .506 | 10.8 | 5.5 | 4.97 | 4.14 |
| Gavin Floyd | TON | sp | 24 | .871 | 223 | .305 | 166 | .529 | 172 | .548 | 52.2 | 6.6 | 6.04 | 6.22 |
| Josh Fogg |   | sp | 30 | .854 | 556 | .308 | 387 | .519 | 400 | .537 | 120.1 | 6.6 | 5.87 | 5.44 |
| Casey Fossum* |   | mr | 29 | .939 | 263 | .357 | 203 | .558 | 209 | .574 | 71.5 | 8.4 | 7.62 | 7.59 |
| Jeff Francis* | MAD | sp | 26 | .758 | 662 | .316 | 421 | .457 | 428 | .464 | 116.0 | 4.9 | 4.36 | 4.37 |
| Frank Francisco | EDG | mr | 27 | .755 | 176 | .307 | 123 | .459 | 125 | .466 | 33.6 | 5.1 | 4.59 | 4.44 |
| Ryan Franklin | LON | mr | 34 | .635 | 251 | .247 | 121 | .382 | 124 | .391 | 28.0 | 3.1 | 2.83 | 2.59 |
| Jason Frasor | MID | mr | 29 | .631 | 155 | .284 | 94 | .388 | 96 | .397 | 23.2 | 3.6 | 3.30 | 2.88 |
| Brian Fuentes* | CCL | cl | 31 | .622 | 163 | .245 | 95 | .373 | 102 | .400 | 23.0 | 3.4 | 3.03 | 3.06 |
| Aaron Fultz* | MAD | mr | 33 | .662 | 109 | .266 | 65 | .411 | 66 | .418 | 15.9 | 3.9 | 3.48 | 3.21 |
| Kason Gabbard* | CRH | sp | 25 | .706 | 233 | .258 | 149 | .433 | 156 | .453 | 36.4 | 4.0 | 3.62 | 3.99 |
| Eric Gagne | GEO | cl | 31 | .670 | 146 | .315 | 91 | .410 | 92 | .414 | 23.4 | 4.1 | 3.64 | 3.56 |
| Armando Galarraga |   | mr | 25 | .844 | 25 | .240 | 22 | .550 | 22 | .550 | 6.4 | 6.7 | 6.01 | 6.35 |
| Sean Gallagher |   | mr | 21 | .999 | 53 | .302 | 46 | .622 | 47 | .635 | 14.9 | 8.9 | 8.20 | 8.95 |
| Yovani Gallardo | LON | sp | 21 | .676 | 318 | .299 | 192 | .412 | 194 | .416 | 47.5 | 3.8 | 3.49 | 3.30 |
| Anderson Garcia |   | mr | 26 | 1.000 | 4 | .500 | 2 | .500 | 2 | .500 | 1.0 | 13.5 | 12.15 | 14.52 |
| Freddy Garcia |   | sp | 31 | .948 | 178 | .348 | 152 | .576 | 157 | .595 | 51.0 | 8.0 | 7.12 | 6.57 |
| Harvey Garcia |   | mr | 23 | .900 | 30 | .367 | 31 | .564 | 31 | .564 | 9.7 | 7.5 | 6.35 | 6.78 |
| Lee Gardner | MAD | mr | 32 | .622 | 236 | .297 | 109 | .350 | 112 | .360 | 28.0 | 3.4 | 3.05 | 2.87 |
| Jon Garland | COP | sp | 27 | .732 | 705 | .284 | 393 | .445 | 397 | .450 | 102.8 | 4.4 | 4.00 | 3.87 |
| Matt Garza | GEO | sp | 23 | .784 | 256 | .344 | 170 | .463 | 174 | .474 | 48.0 | 5.2 | 4.69 | 5.08 |
| Chad Gaudin |   | sp | 24 | .776 | 603 | .305 | 424 | .479 | 432 | .488 | 116.5 | 5.2 | 4.73 | 4.80 |
| Geoff Geary |   | mr | 30 | .797 | 216 | .296 | 135 | .456 | 144 | .486 | 37.7 | 5.0 | 4.53 | 4.98 |
| Justin Germano | CCL | sp | 24 | .733 | 426 | .279 | 251 | .443 | 259 | .458 | 67.0 | 4.5 | 4.07 | 3.93 |
| Dan Giese |   | mr | 30 | .925 | 24 | .167 | 24 | .649 | 24 | .649 | 5.6 | 5.4 | 4.86 | 4.61 |
| Tom Glavine* | WIZ | sp | 41 | .776 | 675 | .290 | 406 | .475 | 410 | .480 | 110.3 | 5.0 | 4.46 | 4.53 |
| Gary Glover |   | mr | 30 | .832 | 243 | .309 | 174 | .521 | 175 | .524 | 49.4 | 5.8 | 5.18 | 5.07 |
| Jimmy Gobble* |   | mr | 25 | .810 | 152 | .329 | 116 | .498 | 118 | .506 | 32.4 | 5.5 | 4.89 | 4.56 |
| Edgar Gonzalez |   | mr | 24 | .808 | 325 | .283 | 220 | .503 | 224 | .513 | 59.1 | 5.2 | 4.69 | 4.67 |
| Enrique Gonzalez |   | mr | 24 | .955 | 10 | .400 | 6 | .545 | 6 | .545 | 2.1 | 8.1 | 8.51 | 9.72 |
| Mike Gonzalez* |   | mr | 29 | .673 | 49 | .306 | 29 | .414 | 29 | .414 | 6.9 | 3.7 | 3.28 | 3.13 |
| Tom Gordon |   | mr | 39 | .773 | 116 | .284 | 81 | .476 | 83 | .488 | 20.9 | 4.6 | 4.23 | 4.55 |
| Tom Gorzelanny* | LON | sp | 24 | .748 | 642 | .305 | 390 | .446 | 401 | .459 | 110.6 | 5.0 | 4.44 | 4.31 |
| Mike Gosling* |   | mr | 26 | .953 | 98 | .378 | 96 | .585 | 97 | .591 | 30.1 | 8.2 | 7.40 | 7.81 |
| John Grabow* |   | mr | 28 | .740 | 160 | .313 | 100 | .439 | 101 | .443 | 29.3 | 5.0 | 4.59 | 4.51 |
| Sean Green |   | mr | 28 | .787 | 212 | .354 | 139 | .457 | 142 | .467 | 38.3 | 5.1 | 4.57 | 4.81 |
| Kevin Gregg | BT | cl | 29 | .627 | 215 | .260 | 137 | .386 | 143 | .403 | 33.1 | 3.6 | 3.19 | 3.15 |
| Zack Greinke | COP | mr | 23 | .747 | 350 | .314 | 233 | .460 | 236 | .465 | 61.8 | 4.6 | 4.10 | 3.77 |
| Jason Grilli | COP | mr | 30 | .714 | 248 | .306 | 148 | .420 | 153 | .435 | 40.4 | 4.5 | 4.11 | 4.09 |
| Lee Gronkiewicz |   | mr | 28 | .651 | 10 | .100 | 7 | .467 | 7 | .467 | 1.1 | 2.5 | 2.24 | 2.92 |
| Eddie Guardado* |   | mr | 36 | .857 | 47 | .298 | 33 | .532 | 34 | .548 | 10.4 | 6.9 | 6.19 | 5.14 |
| Matt Guerrier | MID | mr | 28 | .618 | 248 | .250 | 131 | .373 | 136 | .387 | 30.4 | 3.1 | 2.80 | 2.70 |
| Jeremy Guthrie | MID | sp | 28 | .713 | 526 | .270 | 320 | .443 | 324 | .448 | 78.2 | 4.0 | 3.61 | 3.55 |
| Juan Gutierrez |   | mr | 23 | .845 | 68 | .324 | 49 | .527 | 49 | .527 | 14.4 | 6.1 | 5.46 | 4.71 |
| Angel Guzman |   | mr | 25 | .747 | 89 | .337 | 56 | .438 | 58 | .453 | 15.7 | 4.7 | 4.20 | 4.10 |
| Marc Gwyn |   | cl | 29 | 1.212 | 20 | .300 | 24 | .774 | 24 | .774 | 9.4 | 14.9 | 14.28 | 14.82 |
| Charlie Haeger |   | mr | 23 | .990 | 46 | .304 | 34 | .576 | 35 | .593 | 12.7 | 10.1 | 9.05 | 10.02 |
| Roy Halladay | ROK | sp | 30 | .678 | 722 | .301 | 371 | .400 | 374 | .403 | 93.8 | 3.7 | 3.37 | 3.37 |
| Cole Hamels* | BT | sp | 23 | .686 | 495 | .279 | 320 | .431 | 323 | .435 | 78.8 | 3.9 | 3.48 | 3.12 |
| Jason Hammel | EDG | sp | 24 | .866 | 266 | .331 | 208 | .542 | 210 | .547 | 65.1 | 7.0 | 6.21 | 5.86 |
| Justin Hampson* | CCL | mr | 27 | .636 | 165 | .285 | 81 | .370 | 84 | .384 | 19.5 | 3.3 | 2.97 | 2.77 |
| Josh Hancock |   | mr | 29 | .801 | 40 | .300 | 27 | .482 | 27 | .482 | 7.8 | 5.6 | 5.00 | 5.06 |
| Joel Hanrahan | CCL | sp | 25 | .862 | 157 | .318 | 134 | .543 | 134 | .543 | 41.7 | 7.4 | 6.62 | 7.01 |
| Devern Hansack |   | mr | 29 | .914 | 26 | .269 | 23 | .605 | 23 | .605 | 7.1 | 8.0 | 7.51 | 7.11 |
| J.A. Happ* |   | sp | 24 | 1.323 | 11 | .364 | 19 | .905 | 19 | .905 | 6.7 | 13.9 | 13.52 | 15.13 |
| Aaron Harang | GEO | sp | 29 | .690 | 642 | .288 | 404 | .426 | 412 | .435 | 100.2 | 3.9 | 3.50 | 3.22 |
| Rich Harden | COP | sp | 25 | .627 | 59 | .254 | 41 | .410 | 41 | .410 | 7.6 | 2.7 | 2.40 | 2.80 |
| Dan Haren | LON | sp | 26 | .687 | 661 | .287 | 398 | .426 | 401 | .429 | 102.6 | 4.1 | 3.73 | 3.32 |
| Tim Harikkala |   | sp | 35 | 1.026 | 16 | .563 | 10 | .526 | 10 | .526 | 4.4 | 11.8 | 10.66 | 14.52 |
| Kevin Hart |   | mr | 24 | .566 | 25 | .280 | 15 | .357 | 15 | .357 | 3.1 | 2.6 | 2.29 | 1.62 |
| LaTroy Hawkins | BT | mr | 34 | .698 | 174 | .264 | 97 | .431 | 97 | .431 | 23.3 | 3.8 | 3.42 | 3.43 |
| Aaron Heilman | WIZ | mr | 28 | .634 | 256 | .250 | 134 | .381 | 139 | .395 | 33.0 | 3.4 | 3.11 | 2.71 |
| Mark Hendrickson* | MUL | mr | 33 | .767 | 395 | .322 | 241 | .453 | 242 | .455 | 70.5 | 5.1 | 4.65 | 4.42 |
| Sean Henn* |   | mr | 26 | .898 | 117 | .325 | 100 | .552 | 103 | .569 | 31.3 | 7.6 | 6.93 | 7.47 |
| Brad Hennessey |   | cl | 27 | .734 | 214 | .276 | 128 | .446 | 131 | .456 | 33.0 | 4.4 | 3.92 | 3.87 |
| Clay Hensley |   | sp | 27 | .858 | 170 | .335 | 124 | .521 | 125 | .525 | 40.4 | 7.4 | 6.54 | 6.54 |
| Matt Herges | LON | mr | 37 | .598 | 142 | .211 | 73 | .382 | 73 | .382 | 14.6 | 2.7 | 2.43 | 2.05 |
| Felix Hernandez | ROK | sp | 21 | .751 | 567 | .333 | 366 | .453 | 369 | .457 | 99.6 | 4.7 | 4.24 | 4.27 |
| Livan Hernandez |   | sp | 32 | .870 | 704 | .303 | 480 | .526 | 486 | .532 | 149.1 | 6.6 | 5.91 | 5.94 |
| Orlando Hernandez | Pal | sp | 37 | .685 | 388 | .222 | 269 | .442 | 274 | .451 | 63.0 | 3.8 | 3.45 | 3.26 |
| Roberto Hernandez |   | mr | 42 | .891 | 157 | .344 | 118 | .534 | 121 | .548 | 36.2 | 6.8 | 6.33 | 6.48 |
| Yoel Hernandez |   | mr | 27 | .768 | 51 | .353 | 31 | .463 | 31 | .463 | 9.7 | 5.7 | 5.14 | 4.45 |
| Rich Hill* | BT | sp | 27 | .699 | 527 | .271 | 348 | .429 | 360 | .443 | 89.7 | 4.1 | 3.73 | 3.56 |
| Shawn Hill | WIZ | sp | 26 | .661 | 295 | .261 | 160 | .401 | 165 | .414 | 38.7 | 3.6 | 3.22 | 3.03 |
| Jason Hirsh | WIZ | sp | 25 | .777 | 340 | .250 | 241 | .499 | 243 | .503 | 63.6 | 5.1 | 4.59 | 4.12 |
| Luke Hochevar |   | mr | 23 | .709 | 41 | .244 | 21 | .389 | 24 | .444 | 5.4 | 3.7 | 3.44 | 3.86 |
| Jim Hoey |   | mr | 24 | .785 | 76 | .303 | 55 | .478 | 56 | .487 | 16.2 | 5.9 | 5.31 | 5.43 |
| Trevor Hoffman | Pal | cl | 39 | .634 | 174 | .270 | 92 | .391 | 92 | .391 | 21.7 | 3.4 | 3.07 | 2.23 |
| D.J. Houlton |   | mr | 27 | .738 | 80 | .287 | 52 | .460 | 52 | .460 | 12.7 | 4.1 | 3.68 | 4.16 |
| J.P. Howell* | MID | sp | 24 | .882 | 163 | .374 | 129 | .529 | 132 | .541 | 41.7 | 7.2 | 6.62 | 6.84 |
| Bob Howry | COP | mr | 33 | .670 | 235 | .289 | 136 | .405 | 138 | .411 | 35.1 | 3.9 | 3.49 | 3.10 |
| Jon Huber |   | mr | 25 | .780 | 34 | .353 | 22 | .468 | 22 | .468 | 5.3 | 4.2 | 3.76 | 4.96 |
| Luke Hudson |   | sp | 30 | 1.128 | 8 | .125 | 10 | .769 | 10 | .769 | 3.2 | 12.5 | 13.16 | 13.81 |
| Tim Hudson | GEO | sp | 31 | .660 | 722 | .292 | 351 | .379 | 359 | .388 | 88.6 | 3.6 | 3.20 | 3.12 |
| Phil Hughes | COP | sp | 21 | .699 | 209 | .268 | 134 | .438 | 136 | .444 | 33.1 | 4.0 | 3.69 | 3.61 |
| Eric Hull |   | mr | 27 | .487 | 19 | .211 | 8 | .296 | 8 | .296 | 1.6 | 2.1 | 1.98 | 1.61 |
| Philip Humber |   | mr | 24 | .910 | 27 | .296 | 19 | .594 | 19 | .594 | 6.0 | 7.7 | 6.97 | 5.46 |
| Kei Igawa* |   | sp | 27 | .907 | 204 | .299 | 182 | .581 | 186 | .594 | 54.8 | 7.3 | 6.56 | 6.60 |
| Jason Isringhausen | Pal | cl | 34 | .543 | 179 | .212 | 92 | .345 | 94 | .352 | 18.2 | 2.5 | 2.26 | 2.11 |
| Edwin Jackson |   | sp | 23 | .837 | 516 | .341 | 384 | .509 | 388 | .514 | 119.3 | 6.6 | 6.00 | 6.11 |
| Chuck James* |   | sp | 25 | .804 | 484 | .273 | 353 | .511 | 354 | .512 | 97.9 | 5.5 | 4.91 | 4.69 |
| Casey Janssen | OTR | mr | 25 | .654 | 231 | .273 | 115 | .387 | 118 | .397 | 27.3 | 3.4 | 3.04 | 3.06 |
| Bobby Jenks | OTR | cl | 26 | .488 | 177 | .243 | 69 | .277 | 70 | .281 | 14.4 | 2.0 | 1.80 | 1.49 |
| Jason Jennings |   | sp | 28 | .873 | 319 | .313 | 240 | .539 | 242 | .544 | 75.3 | 6.8 | 6.16 | 5.72 |
| Kelvin Jimenez |   | mr | 26 | .842 | 151 | .358 | 96 | .485 | 100 | .505 | 31.3 | 6.7 | 6.04 | 5.99 |
| Ubaldo Jimenez | TON | sp | 23 | .726 | 233 | .258 | 161 | .455 | 167 | .472 | 43.3 | 4.7 | 4.28 | 3.80 |
| Jim Johnson |   | mr | 24 | .830 | 8 | .375 | 5 | .455 | 5 | .455 | 1.8 | 8.3 | 7.44 | 8.58 |
| Josh Johnson | LON | sp | 23 | .982 | 55 | .455 | 46 | .561 | 46 | .561 | 15.9 | 9.0 | 8.24 | 9.16 |
| Randy Johnson* | ROK | sp | 43 | .669 | 137 | .328 | 91 | .391 | 95 | .408 | 22.8 | 3.6 | 3.26 | 3.34 |
| Tyler Johnson* |   | mr | 26 | .677 | 117 | .231 | 69 | .421 | 72 | .439 | 17.1 | 4.0 | 3.65 | 3.33 |
| Greg Jones |   | mr | 30 | .909 | 29 | .276 | 24 | .571 | 25 | .595 | 7.8 | 8.1 | 7.32 | 7.12 |
| Todd Jones | MUL | cl | 39 | .702 | 206 | .296 | 112 | .423 | 112 | .423 | 28.7 | 4.2 | 3.79 | 3.70 |
| Jorge Julio |   | mr | 28 | .813 | 182 | .330 | 138 | .493 | 141 | .504 | 41.0 | 5.9 | 5.35 | 5.44 |
| Jair Jurrjens |   | sp | 21 | .717 | 93 | .215 | 57 | .467 | 58 | .475 | 13.3 | 4.0 | 3.51 | 3.19 |
| Jeff Karstens |   | mr | 24 | 1.167 | 62 | .371 | 57 | .712 | 57 | .712 | 23.6 | 14.5 | 13.03 | 11.86 |
| Scott Kazmir* | GEO | sp | 23 | .711 | 534 | .333 | 386 | .435 | 393 | .443 | 99.7 | 4.3 | 3.91 | 3.97 |
| Randy Keisler* |   | sp | 31 | .935 | 64 | .281 | 45 | .584 | 45 | .584 | 14.1 | 7.3 | 6.58 | 5.33 |
| Kyle Kendrick |   | sp | 22 | .774 | 402 | .281 | 232 | .465 | 239 | .479 | 63.1 | 4.8 | 4.23 | 4.23 |
| Ian Kennedy |   | sp | 22 | .565 | 52 | .231 | 28 | .364 | 28 | .364 | 5.7 | 2.7 | 2.42 | 2.42 |
| Joe Kennedy* |   | mr | 28 | .775 | 377 | .292 | 226 | .451 | 235 | .469 | 64.9 | 5.2 | 4.75 | 5.09 |
| Logan Kensing |   | mr | 24 | .590 | 37 | .297 | 19 | .322 | 21 | .356 | 5.0 | 3.3 | 3.01 | 3.15 |
| Bobby Keppel |   | mr | 25 | 1.038 | 15 | .333 | 13 | .650 | 13 | .650 | 4.3 | 9.7 | 8.73 | 10.40 |
| Byung-Hyun Kim |   | sp | 28 | .864 | 351 | .316 | 292 | .520 | 308 | .548 | 94.2 | 7.1 | 6.45 | 6.44 |
| Ray King* |   | mr | 33 | .801 | 121 | .256 | 89 | .509 | 91 | .520 | 24.8 | 5.6 | 5.06 | 4.75 |
| Steve Kline* |   | mr | 34 | .755 | 177 | .316 | 93 | .431 | 95 | .440 | 28.1 | 5.3 | 4.95 | 5.03 |
| Dan Kolb |   | mr | 32 | 1.269 | 11 | .455 | 12 | .750 | 12 | .750 | 4.7 | 14.1 | 12.73 | 14.00 |
| Shane Komine |   | mr | 26 | .722 | 26 | .154 | 14 | .452 | 15 | .484 | 3.6 | 4.3 | 3.83 | 3.29 |
| Mike Koplove |   | mr | 30 | .781 | 19 | .316 | 12 | .462 | 13 | .500 | 3.6 | 5.5 | 4.91 | 3.79 |
| John Koronka* |   | sp | 26 | .928 | 44 | .364 | 26 | .500 | 27 | .519 | 10.2 | 9.2 | 8.00 | 7.26 |
| Hong-Chih Kuo* | Pal | sp | 25 | .791 | 95 | .337 | 67 | .479 | 68 | .486 | 20.8 | 6.2 | 5.56 | 5.25 |
| Masumi Kuwata |   | mr | 39 | 1.016 | 69 | .275 | 66 | .641 | 67 | .650 | 22.1 | 9.3 | 8.51 | 7.85 |
| John Lackey | COP | sp | 28 | .680 | 668 | .301 | 376 | .405 | 388 | .418 | 96.0 | 3.8 | 3.47 | 3.40 |
| Aaron Laffey* | EDG | sp | 22 | .728 | 164 | .317 | 85 | .411 | 89 | .430 | 22.6 | 4.1 | 3.71 | 4.02 |
| John Lannan* |   | sp | 22 | .751 | 121 | .273 | 68 | .444 | 70 | .458 | 17.7 | 4.5 | 4.13 | 4.82 |
| Juan Lara* |   | mr | 26 | 1.262 | 3 | .333 | 6 | .857 | 6 | .857 | 2.3 | 15.2 | 13.69 | 14.59 |
| Brian Lawrence |   | sp | 31 | .921 | 103 | .379 | 76 | .547 | 77 | .554 | 26.5 | 8.3 | 7.40 | 7.72 |
| Brandon League |   | mr | 24 | .968 | 43 | .419 | 33 | .569 | 33 | .569 | 11.7 | 9.3 | 8.14 | 8.98 |
| Wilfredo Ledezma* |   | mr | 26 | .848 | 188 | .335 | 147 | .525 | 147 | .525 | 43.9 | 6.5 | 5.99 | 6.13 |
| Cliff Lee* | MID | sp | 28 | .841 | 317 | .300 | 229 | .517 | 236 | .533 | 69.2 | 6.3 | 5.76 | 5.59 |
| Jon Leicester |   | sp | 28 | .834 | 110 | .300 | 73 | .503 | 76 | .524 | 22.8 | 6.5 | 5.78 | 5.14 |
| Anthony Lerew |   | sp | 24 | .985 | 37 | .270 | 35 | .614 | 35 | .614 | 11.1 | 8.1 | 7.71 | 7.62 |
| Jon Lester* | EDG | sp | 23 | .753 | 183 | .279 | 129 | .469 | 130 | .473 | 35.7 | 5.2 | 4.59 | 4.78 |
| Colby Lewis |   | mr | 27 | .868 | 123 | .301 | 90 | .529 | 93 | .547 | 26.9 | 6.4 | 5.79 | 5.79 |
| Jensen Lewis |   | mr | 23 | .616 | 79 | .316 | 45 | .360 | 46 | .368 | 11.3 | 3.4 | 3.11 | 2.81 |
| Brad Lidge | Pal | cl | 30 | .721 | 156 | .288 | 131 | .456 | 135 | .470 | 33.6 | 4.5 | 4.06 | 3.52 |
| Jon Lieber | MUL | sp | 37 | .785 | 256 | .328 | 160 | .468 | 163 | .477 | 45.7 | 5.2 | 4.74 | 4.53 |
| Ted Lilly* | OTR | sp | 31 | .692 | 587 | .261 | 367 | .433 | 370 | .437 | 90.3 | 3.9 | 3.53 | 3.14 |
| Tim Lincecum | WIZ | sp | 23 | .672 | 389 | .283 | 261 | .422 | 263 | .426 | 64.4 | 4.0 | 3.56 | 3.21 |
| Matt Lindstrom | MUL | mr | 27 | .641 | 196 | .327 | 103 | .363 | 106 | .373 | 26.6 | 3.6 | 3.21 | 3.26 |
| Scott Linebrink |   | mr | 30 | .742 | 207 | .271 | 139 | .471 | 140 | .475 | 35.9 | 4.6 | 4.13 | 4.26 |
| Jesse Litsch | EDG | sp | 22 | .761 | 371 | .275 | 219 | .458 | 226 | .473 | 58.1 | 4.6 | 4.24 | 4.48 |
| Wes Littleton |   | mr | 24 | .737 | 156 | .269 | 91 | .444 | 94 | .459 | 24.2 | 4.5 | 4.09 | 4.24 |
| Bobby Livingston* |   | sp | 24 | .864 | 206 | .335 | 130 | .520 | 131 | .524 | 41.3 | 6.6 | 5.94 | 5.52 |
| Radhames Liz |   | mr | 24 | .801 | 71 | .310 | 61 | .500 | 62 | .508 | 18.3 | 6.7 | 6.02 | 6.49 |
| Esteban Loaiza |   | sp | 35 | .872 | 113 | .230 | 92 | .561 | 93 | .567 | 25.8 | 6.3 | 5.60 | 5.79 |
| Kameron Loe |   | sp | 25 | .810 | 464 | .321 | 302 | .491 | 306 | .498 | 88.8 | 5.8 | 5.29 | 5.24 |
| Adam Loewen* |   | sp | 23 | .704 | 91 | .286 | 61 | .427 | 64 | .448 | 15.4 | 4.5 | 4.10 | 5.11 |
| Boone Logan* |   | mr | 22 | .802 | 164 | .317 | 109 | .482 | 109 | .482 | 31.8 | 5.5 | 5.08 | 5.18 |
| Kyle Lohse | COP | sp | 28 | .786 | 616 | .300 | 389 | .469 | 401 | .484 | 112.2 | 5.3 | 4.72 | 4.45 |
| Braden Looper | MAD | sp | 32 | .752 | 582 | .277 | 345 | .462 | 349 | .468 | 93.5 | 4.8 | 4.33 | 4.16 |
| Aquilino Lopez |   | mr | 32 | .751 | 59 | .271 | 33 | .434 | 35 | .461 | 9.5 | 4.9 | 4.44 | 4.68 |
| Javier Lopez* | OTR | mr | 29 | .695 | 124 | .274 | 72 | .414 | 76 | .437 | 18.0 | 4.0 | 3.59 | 3.59 |
| Rodrigo Lopez | CCL | sp | 31 | .772 | 258 | .279 | 160 | .480 | 160 | .480 | 43.1 | 4.9 | 4.40 | 3.97 |
| Derek Lowe | BON | sp | 34 | .692 | 604 | .288 | 352 | .424 | 353 | .425 | 85.0 | 3.8 | 3.45 | 3.55 |
| Mark Lowe |   | mr | 24 | .985 | 6 | .167 | 9 | .692 | 9 | .692 | 2.8 | 9.5 | 8.53 | 7.69 |
| Noah Lowry* |   | sp | 26 | .757 | 503 | .284 | 317 | .457 | 322 | .464 | 83.7 | 4.7 | 4.35 | 4.63 |
| Ruddy Lugo |   | mr | 27 | .800 | 152 | .296 | 113 | .496 | 115 | .504 | 32.1 | 6.0 | 5.38 | 5.08 |
| Brandon Lyon | Pal | mr | 27 | .661 | 242 | .281 | 121 | .394 | 122 | .397 | 30.4 | 3.7 | 3.32 | 2.93 |
| Mike MacDougal |   | mr | 30 | .839 | 131 | .359 | 107 | .514 | 109 | .524 | 33.2 | 7.0 | 6.36 | 6.49 |
| Greg Maddux | Pal | sp | 41 | .729 | 681 | .304 | 351 | .423 | 357 | .430 | 103.6 | 4.7 | 4.24 | 3.54 |
| Ryan Madson | CCL | mr | 26 | .666 | 164 | .262 | 97 | .409 | 99 | .418 | 23.9 | 3.8 | 3.46 | 3.28 |
| Ron Mahay* |   | mr | 36 | .664 | 184 | .261 | 118 | .420 | 119 | .423 | 26.6 | 3.6 | 3.22 | 3.23 |
| Paul Maholm* |   | sp | 25 | .796 | 583 | .312 | 361 | .472 | 367 | .480 | 99.9 | 5.0 | 4.55 | 4.77 |
| John Maine | BT | sp | 26 | .703 | 527 | .275 | 356 | .440 | 361 | .446 | 92.6 | 4.4 | 3.93 | 3.58 |
| Gary Majewski |   | mr | 27 | .962 | 95 | .421 | 61 | .540 | 63 | .558 | 23.2 | 9.1 | 8.17 | 9.01 |
| Shaun Marcum | COP | sp | 25 | .754 | 457 | .267 | 315 | .477 | 320 | .485 | 80.3 | 4.6 | 4.09 | 4.00 |
| Carlos Marmol | WIZ | mr | 24 | .508 | 147 | .259 | 90 | .316 | 94 | .330 | 19.3 | 2.5 | 2.26 | 2.11 |
| Mike Maroth* |   | sp | 29 | 1.006 | 417 | .341 | 339 | .617 | 344 | .627 | 114.2 | 8.9 | 7.95 | 8.28 |
| Jason Marquis | MUL | sp | 28 | .744 | 626 | .268 | 380 | .449 | 393 | .465 | 104.7 | 4.8 | 4.42 | 4.28 |
| Jay Marshall* |   | mr | 24 | .806 | 151 | .311 | 92 | .465 | 96 | .485 | 27.1 | 5.7 | 5.23 | 5.56 |
| Sean Marshall* | LON | sp | 24 | .750 | 330 | .285 | 205 | .460 | 206 | .462 | 55.0 | 4.7 | 4.31 | 4.18 |
| Damaso Marte* | WIZ | mr | 32 | .598 | 109 | .275 | 68 | .374 | 70 | .385 | 14.5 | 2.9 | 2.58 | 2.35 |
| Tom Martin* |   | mr | 37 | .843 | 93 | .301 | 60 | .513 | 61 | .521 | 19.1 | 6.8 | 6.04 | 5.87 |
| Carlos Martinez |   | mr | 25 | 1.551 | 7 | .143 | 15 | 1.154 | 15 | 1.154 | 5.5 | 18.5 | 16.66 | 15.48 |
| Pedro Martinez |   | sp | 35 | .719 | 87 | .379 | 52 | .406 | 54 | .422 | 16.1 | 5.0 | 4.65 | 3.80 |
| Nick Masset |   | mr | 25 | .851 | 142 | .352 | 96 | .497 | 98 | .508 | 31.5 | 7.2 | 6.49 | 6.63 |
| Tom Mastny |   | mr | 26 | .809 | 170 | .335 | 129 | .492 | 131 | .500 | 37.2 | 5.8 | 5.22 | 5.16 |
| Julio Mateo |   | mr | 29 | .646 | 43 | .279 | 20 | .385 | 20 | .385 | 4.6 | 3.4 | 3.12 | 3.28 |
| Daisuke Matsuzaka | OTR | sp | 26 | .731 | 555 | .299 | 394 | .451 | 407 | .466 | 104.1 | 4.6 | 4.12 | 4.10 |
| Marcus McBeth |   | mr | 26 | .803 | 61 | .328 | 42 | .477 | 43 | .489 | 14.3 | 6.7 | 5.90 | 4.65 |
| Macay McBride* |   | mr | 24 | .754 | 95 | .305 | 72 | .462 | 74 | .474 | 20.1 | 5.5 | 4.99 | 5.98 |
| Brandon McCarthy | EDG | sp | 23 | .783 | 340 | .300 | 219 | .477 | 222 | .484 | 64.5 | 5.6 | 5.14 | 4.89 |
| Zach McClellan |   | mr | 28 | .853 | 45 | .444 | 31 | .492 | 31 | .492 | 9.1 | 5.8 | 5.26 | 5.57 |
| Seth McClung |   | mr | 26 | .697 | 34 | .324 | 21 | .412 | 22 | .431 | 5.0 | 3.6 | 3.35 | 3.35 |
| Dustin McGowan | OTR | sp | 25 | .644 | 484 | .273 | 282 | .400 | 284 | .403 | 70.5 | 3.7 | 3.36 | 3.07 |
| Marty McLeary |   | mr | 32 | 1.042 | 23 | .217 | 25 | .735 | 25 | .735 | 7.8 | 9.1 | 8.22 | 7.39 |
| Mark McLemore* |   | mr | 26 | .815 | 102 | .324 | 83 | .516 | 84 | .522 | 24.9 | 6.5 | 5.77 | 5.28 |
| Gil Meche | CRH | sp | 28 | .711 | 663 | .296 | 391 | .432 | 394 | .435 | 100.7 | 4.2 | 3.78 | 3.77 |
| Brandon Medders |   | mr | 27 | .916 | 79 | .266 | 76 | .594 | 77 | .602 | 20.8 | 6.5 | 5.74 | 6.76 |
| Jonathan Meloan |   | mr | 22 | 1.031 | 21 | .333 | 24 | .632 | 25 | .658 | 7.9 | 9.7 | 8.77 | 8.45 |
| Luis Mendoza |   | sp | 23 | .636 | 50 | .240 | 23 | .359 | 25 | .391 | 5.7 | 3.3 | 2.90 | 2.83 |
| Cla Meredith |   | mr | 24 | .721 | 257 | .342 | 140 | .409 | 143 | .418 | 38.1 | 4.2 | 3.87 | 4.28 |
| Jose Mesa |   | mr | 41 | .842 | 164 | .268 | 120 | .524 | 122 | .533 | 34.3 | 6.0 | 5.49 | 5.35 |
| Randy Messenger |   | mr | 25 | .817 | 231 | .351 | 135 | .464 | 136 | .467 | 42.7 | 6.0 | 5.37 | 5.32 |
| Dan Meyer* |   | sp | 25 | .872 | 57 | .316 | 43 | .544 | 43 | .544 | 13.9 | 7.5 | 6.90 | 5.97 |
| Andrew Miller* | GEO | sp | 22 | .821 | 199 | .327 | 151 | .489 | 158 | .511 | 48.0 | 6.6 | 6.07 | 6.31 |
| Jason Miller* |   | mr | 24 | 1.297 | 15 | .333 | 19 | .864 | 19 | .864 | 7.7 | 17.4 | 15.68 | 13.58 |
| Justin Miller |   | mr | 29 | .676 | 156 | .308 | 111 | .429 | 111 | .429 | 26.1 | 3.8 | 3.42 | 2.98 |
| Matt Miller |   | mr | 35 | .800 | 5 | .400 | 2 | .400 | 2 | .400 | 0.8 | 7.2 | 6.48 | 7.48 |
| Trever Miller* |   | mr | 34 | .777 | 132 | .295 | 101 | .479 | 105 | .498 | 28.7 | 5.5 | 5.02 | 4.52 |
| Wade Miller |   | sp | 30 | 1.149 | 53 | .358 | 51 | .729 | 51 | .729 | 19.7 | 13.0 | 11.69 | 11.40 |
| Kevin Millwood |   | sp | 32 | .812 | 571 | .340 | 383 | .486 | 391 | .496 | 116.0 | 6.0 | 5.44 | 5.64 |
| Eric Milton* |   | sp | 31 | .839 | 112 | .313 | 74 | .517 | 74 | .517 | 22.5 | 6.3 | 5.82 | 5.07 |
| Zach Miner |   | mr | 25 | .727 | 173 | .306 | 101 | .435 | 101 | .435 | 25.1 | 4.1 | 3.79 | 3.95 |
| Patrick Misch* |   | mr | 25 | .808 | 133 | .331 | 85 | .483 | 87 | .494 | 24.3 | 5.4 | 4.88 | 4.59 |
| Sergio Mitre |   | sp | 26 | .755 | 522 | .328 | 281 | .424 | 291 | .440 | 84.7 | 5.1 | 4.61 | 4.71 |
| Brian Moehler |   | mr | 35 | .757 | 196 | .301 | 119 | .463 | 119 | .463 | 30.7 | 4.5 | 4.17 | 4.48 |
| Franklin Morales* |   | sp | 21 | .655 | 119 | .269 | 62 | .380 | 64 | .393 | 15.8 | 3.6 | 3.25 | 3.04 |
| Juan Morillo |   | mr | 23 | .741 | 10 | .200 | 7 | .438 | 8 | .500 | 2.2 | 5.4 | 4.86 | 4.74 |
| Matt Morris |   | sp | 32 | .812 | 694 | .320 | 424 | .480 | 433 | .490 | 127.8 | 5.8 | 5.21 | 4.98 |
| Brandon Morrow | CRH | mr | 22 | .723 | 169 | .314 | 130 | .450 | 131 | .453 | 34.1 | 4.9 | 4.37 | 4.47 |
| Dustin Moseley |   | mr | 25 | .747 | 296 | .304 | 172 | .449 | 175 | .457 | 45.4 | 4.5 | 4.00 | 4.00 |
| Guillermo Mota |   | mr | 33 | .747 | 186 | .296 | 120 | .460 | 122 | .467 | 34.9 | 5.2 | 4.76 | 4.26 |
| Jamie Moyer* |   | sp | 44 | .826 | 633 | .303 | 443 | .511 | 448 | .517 | 126.5 | 5.7 | 5.14 | 4.92 |
| Peter Moylan | MAD | mr | 28 | .597 | 252 | .234 | 127 | .354 | 134 | .373 | 27.7 | 2.8 | 2.49 | 2.36 |
| Edward Mujica |   | mr | 23 | .982 | 48 | .333 | 38 | .633 | 38 | .633 | 13.1 | 9.1 | 8.19 | 6.63 |
| Mark Mulder* |   | sp | 29 | 1.357 | 44 | .409 | 49 | .831 | 50 | .847 | 18.9 | 15.0 | 13.92 | 15.59 |
| Carlos Muniz |   | mr | 26 | .425 | 6 | .167 | 3 | .300 | 3 | .300 | 0.6 | 2.4 | 2.12 | 2.03 |
| Arnie Munoz* |   | mr | 25 | 1.075 | 18 | .222 | 20 | .625 | 22 | .688 | 7.3 | 11.6 | 11.11 | 12.15 |
| Scott Munter |   | mr | 27 | .883 | 38 | .368 | 22 | .478 | 22 | .478 | 7.1 | 6.1 | 5.36 | 5.34 |
| Bill Murphy* |   | mr | 26 | .885 | 24 | .375 | 17 | .500 | 18 | .529 | 5.7 | 8.5 | 7.27 | 8.97 |
| A.J. Murray* |   | mr | 25 | .835 | 84 | .226 | 68 | .553 | 68 | .553 | 19.1 | 6.2 | 5.53 | 4.71 |
| Neal Musser* |   | mr | 26 | .936 | 78 | .346 | 69 | .595 | 69 | .595 | 21.5 | 7.8 | 7.06 | 7.27 |
| Mike Mussina |   | sp | 38 | .814 | 512 | .340 | 316 | .482 | 320 | .488 | 97.1 | 5.8 | 5.18 | 4.87 |
| Brett Myers | CRH | cl | 26 | .698 | 173 | .301 | 129 | .440 | 130 | .444 | 33.9 | 4.4 | 4.00 | 3.63 |
| Mike Myers* |   | mr | 38 | .772 | 186 | .285 | 113 | .461 | 116 | .473 | 31.8 | 5.1 | 4.74 | 4.84 |
| Joe Nathan | WIZ | cl | 32 | .574 | 181 | .276 | 99 | .351 | 100 | .355 | 22.4 | 2.9 | 2.54 | 2.08 |
| Pat Neshek | BON | mr | 26 | .591 | 168 | .220 | 105 | .378 | 107 | .385 | 21.6 | 2.8 | 2.48 | 2.12 |
| Josh Newman* |   | mr | 25 | .625 | 5 | .400 | 3 | .375 | 3 | .375 | 0.8 | 3.4 | 3.04 | 1.95 |
| Dustin Nippert |   | mr | 26 | .743 | 137 | .314 | 91 | .464 | 91 | .464 | 23.9 | 4.7 | 4.27 | 4.25 |
| Ricky Nolasco |   | sp | 24 | .856 | 75 | .307 | 48 | .485 | 49 | .495 | 16.4 | 6.9 | 6.21 | 5.71 |
| Leo Nunez |   | mr | 23 | .756 | 127 | .283 | 88 | .484 | 88 | .484 | 23.1 | 4.7 | 4.29 | 3.98 |
| Eric O'Flaherty* | CRH | mr | 22 | .611 | 159 | .277 | 77 | .348 | 82 | .371 | 18.9 | 3.3 | 2.93 | 3.04 |
| Wes Obermueller |   | mr | 30 | .879 | 196 | .332 | 148 | .532 | 152 | .547 | 45.7 | 7.0 | 6.27 | 6.64 |
| Tomo Ohka |   | sp | 31 | .845 | 198 | .293 | 132 | .526 | 132 | .526 | 38.1 | 6.1 | 5.51 | 5.90 |
| Ross Ohlendorf |   | mr | 24 | .603 | 14 | .286 | 10 | .385 | 10 | .385 | 2.3 | 3.3 | 2.93 | 2.94 |
| Will Ohman* | MAD | mr | 29 | .792 | 115 | .339 | 81 | .482 | 82 | .488 | 24.3 | 5.9 | 5.41 | 4.79 |
| Hideki Okajima* | COP | mr | 31 | .561 | 185 | .238 | 93 | .342 | 94 | .346 | 19.6 | 2.5 | 2.30 | 2.03 |
| Darren Oliver* |   | mr | 36 | .648 | 193 | .275 | 107 | .392 | 108 | .396 | 26.6 | 3.7 | 3.35 | 3.19 |
| Scott Olsen* |   | sp | 23 | .888 | 578 | .341 | 447 | .541 | 448 | .542 | 139.9 | 7.0 | 6.42 | 6.54 |
| Garrett Olson* |   | sp | 23 | .917 | 100 | .380 | 89 | .549 | 91 | .562 | 28.8 | 8.0 | 7.20 | 8.46 |
| Ramon Ortiz |   | mr | 34 | .823 | 364 | .305 | 228 | .497 | 234 | .510 | 67.7 | 5.7 | 5.27 | 5.17 |
| Russ Ortiz |   | sp | 33 | .828 | 166 | .319 | 107 | .480 | 113 | .507 | 34.2 | 6.4 | 5.65 | 5.42 |
| Chad Orvella |   | mr | 26 | 1.273 | 36 | .417 | 44 | .786 | 45 | .804 | 19.8 | 19.8 | 20.01 | 18.69 |
| Franquelis Osoria |   | mr | 25 | .743 | 98 | .306 | 52 | .413 | 56 | .444 | 14.6 | 4.5 | 4.17 | 5.09 |
| Roy Oswalt | BT | sp | 29 | .708 | 675 | .307 | 384 | .422 | 391 | .430 | 102.4 | 4.3 | 3.91 | 3.68 |
| Akinori Otsuka |   | mr | 35 | .547 | 99 | .263 | 42 | .321 | 42 | .321 | 9.3 | 2.5 | 2.34 | 1.93 |
| Henry Owens |   | mr | 28 | .682 | 69 | .232 | 44 | .449 | 44 | .449 | 10.9 | 4.3 | 3.84 | 3.33 |
| Micah Owings |   | sp | 24 | .765 | 461 | .273 | 303 | .465 | 317 | .487 | 82.4 | 4.9 | 4.37 | 4.13 |
| Vicente Padilla |   | sp | 29 | .810 | 407 | .319 | 264 | .477 | 273 | .494 | 80.1 | 6.0 | 5.39 | 5.95 |
| Jonathan Papelbon | BON | cl | 26 | .463 | 116 | .216 | 65 | .290 | 69 | .308 | 12.2 | 1.9 | 1.70 | 1.43 |
| Chan Ho Park |   | sp | 34 | 1.122 | 12 | .333 | 15 | .750 | 15 | .750 | 5.4 | 12.2 | 10.95 | 10.88 |
| Chad Paronto |   | mr | 31 | .773 | 143 | .322 | 78 | .433 | 81 | .450 | 22.7 | 5.1 | 4.55 | 4.95 |
| Manny Parra* |   | mr | 24 | .676 | 75 | .320 | 45 | .388 | 47 | .405 | 12.0 | 4.1 | 3.70 | 3.83 |
| John Parrish* |   | mr | 29 | .788 | 172 | .355 | 119 | .469 | 121 | .476 | 35.6 | 6.2 | 5.54 | 6.03 |
| John Patterson |   | sp | 29 | .933 | 110 | .309 | 88 | .579 | 88 | .579 | 29.5 | 8.5 | 7.61 | 7.23 |
| Troy Patton* |   | sp | 21 | .770 | 37 | .189 | 26 | .481 | 28 | .519 | 6.7 | 4.6 | 4.28 | 4.04 |
| Felipe Paulino |   | sp | 23 | .942 | 62 | .274 | 52 | .612 | 52 | .612 | 15.1 | 7.0 | 6.45 | 5.93 |
| Carl Pavano |   | sp | 31 | .713 | 39 | .282 | 20 | .435 | 20 | .435 | 4.8 | 3.7 | 3.43 | 3.54 |
| Jake Peavy | MUL | sp | 26 | .584 | 571 | .273 | 321 | .357 | 327 | .364 | 72.2 | 2.9 | 2.62 | 2.27 |
| Jailen Peguero |   | mr | 26 | .952 | 46 | .326 | 41 | .577 | 42 | .592 | 13.2 | 8.5 | 7.31 | 7.79 |
| Mike Pelfrey |   | sp | 23 | .820 | 243 | .325 | 160 | .468 | 169 | .494 | 52.3 | 6.5 | 5.83 | 5.99 |
| Tony Pena | LON | mr | 25 | .631 | 237 | .232 | 135 | .392 | 140 | .407 | 29.4 | 3.1 | 2.79 | 2.71 |
| Brad Penny | LON | sp | 29 | .685 | 643 | .295 | 348 | .402 | 353 | .408 | 88.1 | 3.8 | 3.43 | 3.41 |
| Joel Peralta | MID | mr | 31 | .765 | 270 | .311 | 172 | .470 | 174 | .475 | 47.6 | 4.9 | 4.40 | 3.75 |
| Troy Percival | OTR | mr | 37 | .505 | 101 | .208 | 49 | .327 | 49 | .327 | 8.5 | 1.9 | 1.73 | 1.52 |
| Juan Perez* |   | mr | 28 | .855 | 37 | .324 | 31 | .544 | 31 | .544 | 9.0 | 6.6 | 5.90 | 6.48 |
| Odalis Perez* |   | sp | 30 | .855 | 494 | .332 | 319 | .510 | 323 | .516 | 99.8 | 6.5 | 5.88 | 5.77 |
| Oliver Perez* | BT | sp | 25 | .696 | 483 | .271 | 334 | .437 | 341 | .446 | 85.5 | 4.3 | 3.91 | 3.76 |
| Rafael Perez* | CRH | mr | 25 | .531 | 154 | .234 | 79 | .335 | 79 | .335 | 14.4 | 2.1 | 1.93 | 1.74 |
| Glen Perkins* |   | mr | 24 | .658 | 79 | .266 | 45 | .391 | 47 | .409 | 10.3 | 3.3 | 2.91 | 3.32 |
| Yusmeiro Petit |   | sp | 22 | .830 | 173 | .266 | 133 | .547 | 133 | .547 | 36.3 | 5.7 | 5.16 | 4.56 |
| Billy Petrick |   | mr | 23 | .871 | 26 | .192 | 25 | .595 | 25 | .595 | 6.3 | 5.9 | 5.28 | 6.15 |
| Andy Pettitte* |   | sp | 35 | .753 | 689 | .322 | 414 | .452 | 415 | .453 | 112.3 | 4.7 | 4.22 | 4.27 |
| Heath Phillips* |   | mr | 25 | .912 | 27 | .333 | 19 | .559 | 19 | .559 | 6.0 | 7.8 | 6.66 | 7.17 |
| Carmen Pignatiello* |   | mr | 24 | 1.125 | 4 | .500 | 6 | .750 | 6 | .750 | 1.5 | 6.8 | 6.07 | 9.22 |
| Joel Pineiro |   | mr | 28 | .807 | 317 | .303 | 210 | .501 | 212 | .506 | 59.7 | 5.5 | 4.95 | 4.68 |
| Renyel Pinto* |   | mr | 24 | .696 | 144 | .264 | 106 | .438 | 109 | .450 | 24.4 | 3.8 | 3.37 | 3.79 |
| Sidney Ponson |   | sp | 30 | .949 | 131 | .359 | 104 | .575 | 107 | .591 | 34.7 | 8.3 | 7.47 | 8.04 |
| Bret Prinz |   | mr | 30 | .946 | 12 | .250 | 10 | .625 | 10 | .625 | 3.1 | 8.4 | 7.53 | 7.00 |
| Scott Proctor |   | mr | 30 | .738 | 256 | .258 | 173 | .453 | 179 | .469 | 47.0 | 4.8 | 4.41 | 4.41 |
| J.J. Putz | MID | cl | 30 | .454 | 157 | .197 | 74 | .285 | 76 | .292 | 11.8 | 1.5 | 1.33 | 1.21 |
| Chad Qualls | BON | mr | 28 | .732 | 229 | .323 | 149 | .432 | 152 | .441 | 38.3 | 4.2 | 3.76 | 4.07 |
| Aaron Rakers |   | mr | 30 | .500 | 4 | .250 | 1 | .250 | 1 | .250 | 0.3 | 2.3 | 2.03 | 1.95 |
| Edwar Ramirez |   | mr | 26 | .961 | 49 | .367 | 61 | .592 | 64 | .621 | 21.1 | 9.2 | 8.13 | 7.95 |
| Elizardo Ramirez |   | sp | 24 | .951 | 52 | .288 | 44 | .603 | 44 | .603 | 13.9 | 8.0 | 6.91 | 7.69 |
| Erasmo Ramirez* |   | mr | 31 | .677 | 25 | .280 | 11 | .379 | 11 | .379 | 2.9 | 3.9 | 3.69 | 4.09 |
| Horacio Ramirez* |   | sp | 27 | .913 | 362 | .348 | 253 | .551 | 255 | .556 | 81.6 | 7.5 | 6.74 | 7.17 |
| Ramon Ramirez | LON | mr | 25 | .891 | 54 | .352 | 41 | .526 | 42 | .538 | 13.8 | 7.3 | 6.46 | 5.24 |
| Stephen Randolph* |   | mr | 33 | 1.231 | 34 | .500 | 59 | .756 | 60 | .769 | 23.5 | 15.9 | 14.28 | 13.68 |
| Clay Rapada* |   | mr | 26 | 1.294 | 5 | .200 | 12 | .923 | 12 | .923 | 4.0 | 13.7 | 12.29 | 11.59 |
| Darrell Rasner |   | sp | 26 | .821 | 86 | .291 | 55 | .495 | 57 | .514 | 17.2 | 6.3 | 5.66 | 5.56 |
| Jon Rauch | TON | mr | 28 | .619 | 255 | .267 | 134 | .379 | 134 | .379 | 31.1 | 3.2 | 2.88 | 2.53 |
| Chris Ray | MID | cl | 25 | .674 | 110 | .273 | 76 | .425 | 78 | .436 | 18.7 | 4.0 | 3.54 | 3.42 |
| Tim Redding | CCL | sp | 29 | .757 | 267 | .277 | 167 | .456 | 171 | .467 | 44.8 | 4.8 | 4.32 | 4.59 |
| Mark Redman* |   | sp | 33 | .903 | 148 | .358 | 108 | .540 | 110 | .550 | 36.6 | 8.0 | 7.16 | 7.09 |
| Chris Reitsma |   | mr | 29 | .941 | 92 | .370 | 64 | .557 | 64 | .557 | 22.7 | 8.5 | 7.77 | 7.52 |
| Chris Resop |   | mr | 24 | .872 | 13 | .231 | 8 | .471 | 8 | .471 | 2.1 | 4.3 | 3.88 | 4.00 |
| Al Reyes |   | cl | 37 | .714 | 148 | .243 | 119 | .469 | 121 | .476 | 30.1 | 4.5 | 4.02 | 3.60 |
| Anthony Reyes |   | sp | 25 | .802 | 332 | .277 | 235 | .496 | 244 | .515 | 67.9 | 5.7 | 5.12 | 4.78 |
| Dennys Reyes* |   | mr | 30 | .810 | 94 | .351 | 64 | .460 | 66 | .475 | 19.2 | 5.9 | 5.30 | 6.08 |
| Jo-Jo Reyes* |   | sp | 22 | .877 | 163 | .282 | 125 | .543 | 126 | .548 | 35.4 | 6.2 | 5.66 | 6.06 |
| John Rheinecker* |   | mr | 28 | .856 | 160 | .325 | 126 | .527 | 128 | .536 | 37.4 | 6.5 | 6.01 | 6.64 |
| Jeff Ridgway* |   | mr | 26 | 2.400 | 7 | .857 | 13 | 1.300 | 14 | 1.400 | 11.3 | 304.2 | 273.81 | 276.02 |
| Juan Rincon |   | mr | 28 | .793 | 183 | .306 | 132 | .485 | 135 | .496 | 38.7 | 5.8 | 5.25 | 5.31 |
| Royce Ring* |   | mr | 26 | .584 | 49 | .245 | 34 | .386 | 34 | .386 | 6.5 | 2.8 | 2.63 | 3.33 |
| David Riske | CRH | mr | 30 | .706 | 201 | .264 | 127 | .439 | 128 | .443 | 31.8 | 4.1 | 3.69 | 3.46 |
| Mariano Rivera | ROK | cl | 37 | .644 | 199 | .322 | 108 | .366 | 114 | .386 | 27.1 | 3.4 | 3.08 | 2.92 |
| Saul Rivera | BT | mr | 29 | .678 | 289 | .301 | 160 | .402 | 162 | .407 | 39.8 | 3.8 | 3.46 | 3.39 |
| Connor Robertson |   | mr | 25 | 1.418 | 10 | .600 | 11 | .733 | 12 | .800 | 6.0 | 27.1 | 24.40 | 20.56 |
| Nate Robertson* |   | sp | 29 | .787 | 574 | .308 | 376 | .481 | 379 | .485 | 106.9 | 5.4 | 4.87 | 4.80 |
| Fernando Rodney | OTR | mr | 30 | .698 | 140 | .293 | 94 | .422 | 97 | .435 | 24.9 | 4.3 | 3.98 | 3.74 |
| Francisco Rodriguez | BON | cl | 25 | .605 | 157 | .299 | 109 | .382 | 110 | .386 | 27.1 | 3.6 | 3.26 | 2.74 |
| Wandy Rodriguez* | MUL | sp | 28 | .743 | 535 | .293 | 362 | .463 | 367 | .469 | 95.5 | 4.6 | 4.23 | 3.94 |
| Brian Rogers |   | mr | 24 | 2.000 | 5 | .200 | 10 | 1.111 | 10 | 1.111 | 4.8 | 26.0 | 19.48 | 17.03 |
| Kenny Rogers* |   | sp | 42 | .770 | 205 | .278 | 133 | .484 | 134 | .487 | 36.0 | 5.1 | 4.62 | 4.48 |
| J.C. Romero* |   | mr | 31 | .664 | 150 | .240 | 102 | .430 | 104 | .439 | 21.4 | 3.4 | 3.08 | 3.35 |
| Francisco Rosario |   | mr | 26 | .908 | 82 | .378 | 66 | .520 | 70 | .551 | 23.5 | 8.1 | 7.22 | 6.89 |
| Ryan Rowland-Smith* |   | mr | 24 | .772 | 105 | .333 | 78 | .464 | 80 | .476 | 21.3 | 5.0 | 4.46 | 4.27 |
| B.J. Ryan* |   | cl | 31 | .964 | 17 | .353 | 15 | .600 | 15 | .600 | 5.3 | 10.2 | 9.90 | 10.86 |
| Jae Kuk Ryu |   | mr | 24 | .913 | 79 | .367 | 58 | .527 | 62 | .564 | 18.9 | 7.3 | 6.56 | 7.17 |
| Kirk Saarloos |   | mr | 28 | .907 | 144 | .319 | 112 | .557 | 115 | .572 | 34.5 | 7.1 | 6.55 | 6.75 |
| C.C. Sabathia* | CRH | sp | 26 | .684 | 701 | .311 | 397 | .407 | 405 | .415 | 98.2 | 3.7 | 3.30 | 3.12 |
| Takashi Saito | Pal | cl | 37 | .448 | 135 | .207 | 65 | .278 | 68 | .291 | 10.3 | 1.4 | 1.29 | 1.28 |
| Juan Salas |   | mr | 28 | .796 | 113 | .257 | 82 | .488 | 87 | .518 | 24.5 | 6.0 | 5.47 | 5.39 |
| Brad Salmon |   | mr | 27 | .705 | 65 | .292 | 44 | .436 | 45 | .446 | 11.2 | 4.3 | 3.77 | 4.03 |
| Chris Sampson |   | sp | 29 | .819 | 414 | .285 | 257 | .492 | 264 | .506 | 75.2 | 5.6 | 5.01 | 4.96 |
| Brian Sanches |   | mr | 28 | 1.018 | 40 | .175 | 46 | .676 | 47 | .691 | 12.8 | 7.7 | 7.08 | 7.73 |
| Anibal Sanchez | MAD | sp | 23 | .930 | 113 | .354 | 82 | .543 | 84 | .556 | 29.1 | 8.8 | 7.85 | 7.90 |
| Jonathan Sanchez* |   | mr | 24 | .824 | 135 | .363 | 117 | .492 | 122 | .513 | 34.4 | 6.0 | 5.36 | 6.06 |
| Romulo Sanchez |   | mr | 23 | .755 | 51 | .275 | 34 | .466 | 35 | .479 | 7.9 | 4.0 | 3.56 | 4.20 |
| Ervin Santana | BON | sp | 24 | .854 | 457 | .324 | 358 | .530 | 366 | .542 | 107.8 | 6.5 | 5.82 | 5.69 |
| Johan Santana* | ROK | sp | 28 | .679 | 554 | .271 | 382 | .435 | 386 | .440 | 88.2 | 3.6 | 3.26 | 2.98 |
| Victor Santos |   | mr | 30 | .936 | 185 | .303 | 166 | .585 | 169 | .595 | 49.7 | 7.1 | 6.36 | 6.55 |
| Dennis Sarfate |   | mr | 26 | .435 | 16 | .313 | 8 | .258 | 8 | .258 | 1.5 | 1.6 | 1.46 | 0.96 |
| Joe Saunders* | MID | sp | 26 | .792 | 358 | .330 | 227 | .480 | 228 | .482 | 66.0 | 5.5 | 4.98 | 4.96 |
| Curt Schilling | Pal | sp | 40 | .748 | 486 | .296 | 290 | .458 | 292 | .461 | 80.0 | 4.8 | 4.29 | 3.90 |
| Jason Schmidt |   | sp | 34 | .873 | 84 | .333 | 67 | .536 | 68 | .544 | 21.3 | 7.3 | 6.73 | 6.40 |
| Scott Schoeneweis* |   | mr | 33 | .797 | 185 | .292 | 129 | .487 | 132 | .498 | 36.8 | 5.6 | 5.06 | 4.97 |
| Chris Schroder | CCL | mr | 28 | .568 | 130 | .262 | 65 | .339 | 67 | .349 | 14.8 | 2.8 | 2.64 | 2.40 |
| Mike Schultz |   | mr | 27 | .667 | 2 | .500 | 1 | .333 | 1 | .333 | 0.0 | 0.0 | 0.00 | 2.79 |
| Rudy Seanez |   | mr | 38 | .733 | 215 | .316 | 144 | .438 | 148 | .450 | 40.5 | 4.8 | 4.32 | 4.43 |
| Bobby Seay* | ROK | mr | 29 | .619 | 133 | .278 | 69 | .365 | 71 | .376 | 16.3 | 3.2 | 2.84 | 2.39 |
| Chris Seddon* |   | sp | 23 | .871 | 73 | .370 | 45 | .495 | 46 | .505 | 17.0 | 8.2 | 7.94 | 7.56 |
| Zack Segovia |   | sp | 24 | 1.159 | 19 | .368 | 16 | .696 | 16 | .696 | 6.3 | 12.1 | 10.17 | 7.45 |
| Aaron Sele |   | mr | 37 | .970 | 193 | .378 | 143 | .572 | 145 | .580 | 48.1 | 8.2 | 7.26 | 6.97 |
| Jae Seo |   | sp | 30 | 1.027 | 189 | .386 | 153 | .617 | 157 | .633 | 56.5 | 10.1 | 8.81 | 8.97 |
| Dan Serafini* |   | mr | 33 | .750 | 1 | .000 | 2 | .500 | 3 | .750 | 0.6 | 15.8 | 14.22 | 33.46 |
| Josh Sharpless |   | mr | 26 | 1.400 | 16 | .250 | 20 | .952 | 20 | .952 | 7.5 | 15.7 | 14.09 | 11.87 |
| Tom Shearn |   | sp | 29 | .847 | 100 | .240 | 76 | .555 | 76 | .555 | 20.2 | 5.7 | 5.00 | 5.10 |
| Ben Sheets | TON | sp | 28 | .707 | 431 | .281 | 259 | .438 | 260 | .439 | 70.5 | 4.5 | 4.04 | 3.53 |
| George Sherrill* | ROK | mr | 30 | .553 | 104 | .231 | 63 | .346 | 64 | .352 | 13.5 | 2.7 | 2.39 | 1.96 |
| James Shields | BON | sp | 25 | .697 | 616 | .282 | 373 | .427 | 383 | .438 | 93.9 | 3.9 | 3.54 | 3.24 |
| Scot Shields | ROK | mr | 31 | .643 | 199 | .276 | 127 | .397 | 131 | .409 | 30.1 | 3.5 | 3.16 | 3.31 |
| Brian Shouse* | OTR | mr | 38 | .616 | 153 | .301 | 68 | .338 | 70 | .348 | 17.3 | 3.2 | 2.93 | 2.79 |
| Paul Shuey |   | mr | 36 | .942 | 80 | .375 | 74 | .587 | 74 | .587 | 22.9 | 7.9 | 7.22 | 7.85 |
| Carlos Silva | MID | sp | 28 | .751 | 699 | .299 | 380 | .448 | 384 | .453 | 102.1 | 4.5 | 4.09 | 4.05 |
| Jason Simontacchi |   | sp | 33 | .940 | 241 | .340 | 184 | .571 | 187 | .581 | 58.4 | 7.4 | 6.69 | 6.63 |
| Andrew Sisco* |   | mr | 24 | .919 | 47 | .362 | 42 | .568 | 43 | .581 | 14.9 | 9.4 | 8.65 | 8.28 |
| Doug Slaten* |   | mr | 27 | .760 | 117 | .316 | 77 | .472 | 77 | .472 | 21.3 | 5.1 | 4.76 | 4.74 |
| Kevin Slowey |   | sp | 23 | .850 | 223 | .296 | 164 | .552 | 164 | .552 | 47.9 | 6.3 | 5.82 | 5.22 |
| Joe Smith | LON | mr | 23 | .757 | 129 | .349 | 88 | .429 | 95 | .463 | 26.3 | 5.3 | 4.80 | 5.04 |
| Matt Smith* |   | mr | 28 | .868 | 15 | .267 | 16 | .593 | 16 | .593 | 4.5 | 10.1 | 9.14 | 12.02 |
| John Smoltz | WIZ | sp | 40 | .669 | 587 | .303 | 342 | .401 | 346 | .406 | 88.1 | 3.9 | 3.47 | 3.07 |
| Ian Snell |   | sp | 25 | .739 | 607 | .308 | 395 | .448 | 403 | .457 | 105.4 | 4.6 | 4.10 | 4.02 |
| Kyle Snyder |   | mr | 29 | .716 | 156 | .244 | 107 | .442 | 113 | .467 | 28.7 | 4.8 | 4.28 | 4.41 |
| Andy Sonnanstine |   | sp | 24 | .812 | 408 | .326 | 274 | .495 | 279 | .504 | 74.2 | 5.1 | 4.60 | 4.62 |
| Joakim Soria | BON | cl | 23 | .510 | 172 | .250 | 84 | .311 | 85 | .315 | 16.9 | 2.2 | 1.99 | 1.63 |
| Rafael Soriano | GEO | mr | 27 | .587 | 177 | .198 | 107 | .388 | 109 | .395 | 20.9 | 2.6 | 2.35 | 2.05 |
| Jorge Sosa |   | mr | 30 | .719 | 361 | .274 | 212 | .441 | 212 | .441 | 54.9 | 4.3 | 3.95 | 3.63 |
| Jeremy Sowers* |   | sp | 24 | .858 | 244 | .303 | 157 | .518 | 161 | .531 | 50.4 | 6.8 | 6.07 | 5.75 |
| Justin Speier | MID | mr | 33 | .614 | 129 | .233 | 74 | .374 | 78 | .394 | 17.1 | 3.1 | 2.77 | 2.43 |
| Ryan Speier |   | mr | 27 | .814 | 54 | .352 | 37 | .481 | 38 | .494 | 10.0 | 5.1 | 4.51 | 4.95 |
| Levale Speigner |   | mr | 26 | .919 | 152 | .355 | 109 | .551 | 109 | .551 | 36.1 | 8.0 | 7.31 | 7.38 |
| Russ Springer | WIZ | mr | 38 | .514 | 166 | .229 | 79 | .307 | 82 | .319 | 15.6 | 2.1 | 1.92 | 1.63 |
| Chris Spurling |   | mr | 30 | .808 | 175 | .326 | 109 | .484 | 111 | .493 | 32.9 | 5.9 | 5.32 | 5.27 |
| Jason Standridge |   | mr | 28 | .971 | 28 | .321 | 25 | .610 | 25 | .610 | 8.3 | 9.0 | 8.78 | 8.08 |
| Jason Stanford* |   | mr | 30 | .718 | 92 | .337 | 47 | .398 | 49 | .415 | 14.0 | 4.7 | 4.30 | 4.57 |
| Mike Stanton* |   | mr | 40 | .836 | 194 | .356 | 128 | .487 | 133 | .506 | 40.6 | 6.3 | 5.70 | 5.85 |
| Tim Stauffer | MAD | sp | 25 | 1.305 | 27 | .370 | 37 | .822 | 38 | .844 | 16.0 | 18.8 | 16.95 | 18.32 |
| Mitch Stetter* |   | mr | 26 | .567 | 12 | .167 | 6 | .300 | 8 | .400 | 1.4 | 2.5 | 2.25 | 1.86 |
| Brian Stokes |   | mr | 27 | .933 | 220 | .359 | 164 | .558 | 167 | .568 | 56.0 | 8.2 | 7.28 | 7.70 |
| Ricky Stone |   | mr | 32 | 1.348 | 15 | .200 | 22 | .957 | 23 | 1.000 | 6.8 | 11.4 | 10.29 | 10.09 |
| Huston Street | GEO | cl | 23 | .543 | 119 | .252 | 68 | .342 | 68 | .342 | 14.1 | 2.5 | 2.29 | 1.84 |
| Eric Stults* |   | mr | 27 | .866 | 126 | .357 | 94 | .525 | 95 | .531 | 29.9 | 7.0 | 6.27 | 6.25 |
| Jeff Suppan |   | sp | 32 | .801 | 708 | .318 | 431 | .469 | 442 | .481 | 129.4 | 5.6 | 5.07 | 4.84 |
| Jon Switzer* |   | mr | 27 | .911 | 66 | .379 | 49 | .557 | 49 | .557 | 15.5 | 7.4 | 6.62 | 6.47 |
| Brian Tallet* | EDG | mr | 29 | .611 | 178 | .270 | 96 | .360 | 102 | .382 | 24.0 | 3.4 | 3.12 | 2.68 |
| Taylor Tankersley* |   | mr | 24 | .718 | 120 | .317 | 90 | .439 | 93 | .454 | 22.2 | 4.3 | 3.80 | 4.45 |
| Jack Taschner* |   | mr | 29 | .711 | 137 | .292 | 99 | .446 | 100 | .450 | 26.4 | 4.8 | 4.28 | 3.92 |
| Jordan Tata |   | sp | 25 | .972 | 45 | .333 | 38 | .594 | 40 | .625 | 11.8 | 7.8 | 6.83 | 6.06 |
| Ty Taubenheim |   | sp | 24 | .972 | 14 | .286 | 14 | .583 | 15 | .625 | 4.9 | 9.5 | 7.98 | 7.56 |
| Julian Tavarez |   | sp | 34 | .779 | 455 | .301 | 283 | .469 | 290 | .480 | 79.5 | 5.2 | 4.78 | 4.83 |
| Robinson Tejeda |   | sp | 25 | .889 | 302 | .308 | 249 | .548 | 255 | .562 | 79.2 | 7.4 | 6.73 | 6.77 |
| Joe Thatcher* |   | mr | 25 | .492 | 61 | .197 | 26 | .306 | 27 | .318 | 5.1 | 2.1 | 1.97 | 1.49 |
| Brad Thompson |   | mr | 25 | .869 | 451 | .297 | 303 | .522 | 316 | .545 | 90.7 | 6.2 | 5.68 | 5.99 |
| Mike Thompson |   | mr | 26 | .931 | 58 | .293 | 39 | .520 | 42 | .560 | 12.9 | 7.1 | 6.67 | 6.23 |
| Rich Thompson |   | mr | 22 | 1.268 | 16 | .375 | 28 | .875 | 28 | .875 | 9.7 | 13.1 | 11.75 | 11.85 |
| John Thomson |   | sp | 33 | .811 | 40 | .325 | 22 | .478 | 22 | .478 | 6.5 | 5.5 | 4.93 | 4.19 |
| Matt Thornton* | CRH | mr | 30 | .783 | 162 | .340 | 121 | .486 | 123 | .494 | 32.5 | 5.2 | 4.67 | 4.35 |
| Erick Threets* |   | mr | 25 | 1.200 | 11 | .455 | 11 | .733 | 11 | .733 | 4.7 | 18.1 | 16.26 | 14.38 |
| Mike Timlin | OTR | mr | 41 | .664 | 167 | .234 | 88 | .396 | 91 | .410 | 20.2 | 3.2 | 2.95 | 2.96 |
| Brett Tomko |   | mr | 34 | .809 | 415 | .316 | 292 | .497 | 294 | .500 | 83.9 | 5.6 | 5.18 | 4.96 |
| Salomon Torres |   | mr | 35 | .761 | 158 | .316 | 104 | .450 | 108 | .468 | 29.0 | 4.9 | 4.45 | 4.78 |
| Josh Towers |   | sp | 30 | .832 | 347 | .320 | 237 | .505 | 243 | .518 | 72.3 | 6.0 | 5.47 | 5.15 |
| Billy Traber* |   | mr | 27 | .835 | 136 | .338 | 88 | .484 | 90 | .495 | 28.4 | 6.3 | 5.81 | 5.30 |
| Steve Trachsel |   | sp | 36 | .814 | 549 | .286 | 350 | .499 | 352 | .501 | 103.7 | 6.0 | 5.32 | 5.34 |
| Chin-hui Tsao |   | mr | 26 | .642 | 69 | .217 | 40 | .412 | 41 | .423 | 9.1 | 3.4 | 2.99 | 2.74 |
| Derrick Turnbow | MAD | mr | 29 | .582 | 156 | .256 | 110 | .377 | 112 | .384 | 22.6 | 2.9 | 2.70 | 3.02 |
| Lino Urdaneta |   | mr | 27 | 1.400 | 4 | .250 | 5 | 1.000 | 5 | 1.000 | 2.0 | 18.0 | 16.20 | 16.28 |
| Jose Valverde | WIZ | cl | 27 | .611 | 151 | .258 | 103 | .389 | 106 | .400 | 22.3 | 3.1 | 2.81 | 2.77 |
| John Van Benschoten |   | sp | 27 | .921 | 139 | .367 | 107 | .527 | 112 | .552 | 39.6 | 9.2 | 8.22 | 8.51 |
| Rick VandenHurk |   | sp | 22 | .916 | 231 | .342 | 217 | .573 | 220 | .580 | 68.4 | 7.6 | 6.79 | 6.50 |
| Claudio Vargas |   | sp | 29 | .819 | 419 | .310 | 307 | .507 | 309 | .511 | 91.2 | 6.1 | 5.50 | 5.38 |
| Jason Vargas* |   | sp | 24 | .964 | 41 | .317 | 31 | .608 | 31 | .608 | 11.3 | 9.5 | 8.85 | 8.95 |
| Virgil Vasquez |   | sp | 25 | 1.154 | 61 | .328 | 61 | .753 | 62 | .765 | 22.9 | 12.6 | 11.15 | 10.58 |
| Javier Vazquez | Pal | sp | 30 | .700 | 583 | .288 | 384 | .435 | 391 | .443 | 96.1 | 4.0 | 3.59 | 3.29 |
| Jose Veras |   | mr | 26 | .552 | 27 | .222 | 15 | .366 | 15 | .366 | 3.4 | 3.2 | 2.92 | 2.52 |
| Justin Verlander | COP | sp | 24 | .668 | 577 | .279 | 345 | .398 | 364 | .420 | 89.8 | 4.0 | 3.61 | 3.53 |
| Jamie Vermilyea |   | mr | 25 | .500 | 20 | .250 | 6 | .273 | 6 | .273 | 1.1 | 1.6 | 1.47 | 1.43 |
| Carlos Villanueva | TON | mr | 23 | .740 | 318 | .267 | 231 | .472 | 234 | .479 | 57.8 | 4.5 | 4.09 | 4.03 |
| Oscar Villarreal |   | mr | 25 | .722 | 236 | .292 | 144 | .429 | 148 | .440 | 40.5 | 4.8 | 4.29 | 3.88 |
| Ron Villone* |   | mr | 37 | .668 | 125 | .248 | 71 | .403 | 74 | .420 | 16.2 | 3.4 | 3.10 | 3.74 |
| Luis Vizcaino | LON | mr | 32 | .719 | 221 | .271 | 151 | .452 | 153 | .458 | 38.9 | 4.6 | 4.18 | 3.70 |
| Edinson Volquez |   | sp | 23 | .750 | 99 | .303 | 68 | .456 | 70 | .470 | 18.8 | 5.0 | 4.47 | 4.63 |
| Billy Wagner* | BT | cl | 35 | .611 | 172 | .285 | 106 | .376 | 108 | .383 | 24.3 | 3.1 | 2.88 | 2.66 |
| Ryan Wagner |   | mr | 24 | .873 | 54 | .333 | 39 | .534 | 39 | .534 | 12.0 | 6.9 | 6.19 | 6.18 |
| Adam Wainwright | MAD | sp | 25 | .721 | 654 | .304 | 376 | .426 | 385 | .437 | 100.5 | 4.4 | 4.03 | 4.01 |
| Tim Wakefield | OTR | sp | 40 | .753 | 600 | .282 | 374 | .468 | 378 | .472 | 104.5 | 5.0 | 4.48 | 4.14 |
| Jamie Walker* | OTR | mr | 35 | .658 | 192 | .266 | 102 | .395 | 104 | .403 | 25.5 | 3.7 | 3.36 | 3.19 |
| Tyler Walker |   | mr | 31 | .635 | 40 | .300 | 20 | .377 | 20 | .377 | 3.6 | 2.3 | 2.03 | 2.30 |
| Chien-Ming Wang | MID | sp | 27 | .692 | 643 | .295 | 335 | .407 | 343 | .417 | 83.6 | 3.8 | 3.40 | 3.54 |
| John Wasdin |   | mr | 34 | .954 | 74 | .419 | 52 | .559 | 52 | .559 | 17.1 | 8.0 | 7.06 | 7.40 |
| Jarrod Washburn* |   | sp | 32 | .758 | 627 | .284 | 386 | .460 | 394 | .470 | 105.4 | 4.9 | 4.41 | 4.33 |
| Ehren Wassermann |   | mr | 26 | .606 | 71 | .282 | 32 | .340 | 34 | .362 | 7.4 | 2.9 | 2.61 | 2.47 |
| David Weathers | TON | cl | 37 | .669 | 244 | .258 | 131 | .399 | 136 | .415 | 33.6 | 3.9 | 3.51 | 2.95 |
| Jeff Weaver |   | sp | 30 | .876 | 511 | .327 | 348 | .530 | 356 | .542 | 110.1 | 6.8 | 6.08 | 5.74 |
| Jered Weaver | OTR | sp | 24 | .745 | 516 | .312 | 311 | .447 | 313 | .450 | 89.9 | 5.1 | 4.52 | 4.24 |
| Brandon Webb | TON | sp | 28 | .630 | 692 | .285 | 367 | .376 | 372 | .382 | 88.2 | 3.3 | 3.02 | 2.82 |
| Todd Wellemeyer |   | mr | 28 | .752 | 239 | .276 | 164 | .465 | 167 | .473 | 42.9 | 4.7 | 4.39 | 4.68 |
| David Wells* |   | sp | 44 | .861 | 545 | .328 | 361 | .520 | 364 | .524 | 111.8 | 6.5 | 5.76 | 5.54 |
| Kip Wells |   | sp | 30 | .828 | 522 | .320 | 376 | .501 | 385 | .513 | 114.3 | 6.2 | 5.69 | 5.44 |
| Jake Westbrook | MID | sp | 29 | .729 | 481 | .304 | 278 | .429 | 284 | .438 | 74.5 | 4.4 | 3.97 | 4.28 |
| Dan Wheeler | Pal | mr | 29 | .757 | 202 | .312 | 151 | .470 | 154 | .480 | 41.2 | 4.9 | 4.47 | 4.04 |
| Bill White* |   | mr | 28 | .768 | 23 | .304 | 19 | .452 | 21 | .500 | 5.2 | 5.2 | 4.53 | 5.63 |
| Rick White |   | mr | 38 | .913 | 122 | .352 | 90 | .556 | 90 | .556 | 29.2 | 7.9 | 6.83 | 6.68 |
| Sean White |   | mr | 26 | .777 | 119 | .277 | 73 | .442 | 81 | .491 | 21.7 | 5.4 | 4.98 | 5.24 |
| Bob Wickman |   | cl | 38 | .744 | 167 | .299 | 104 | .448 | 107 | .461 | 30.8 | 5.3 | 4.95 | 4.33 |
| Dave Williams* |   | sp | 28 | 1.543 | 20 | .500 | 27 | .931 | 27 | .931 | 13.0 | 27.0 | 24.30 | 24.43 |
| Jerome Williams |   | sp | 25 | .866 | 101 | .277 | 77 | .550 | 77 | .550 | 22.5 | 6.6 | 6.09 | 6.43 |
| Todd Williams |   | mr | 36 | .829 | 48 | .354 | 30 | .469 | 31 | .484 | 9.6 | 6.1 | 5.40 | 6.25 |
| Woody Williams |   | sp | 40 | .835 | 632 | .286 | 426 | .511 | 438 | .526 | 129.0 | 6.2 | 5.56 | 5.26 |
| Scott Williamson |   | mr | 31 | .661 | 36 | .306 | 25 | .410 | 25 | .410 | 7.8 | 5.1 | 4.40 | 3.62 |
| Dontrelle Willis* |   | sp | 25 | .846 | 666 | .318 | 478 | .507 | 492 | .522 | 147.7 | 6.4 | 5.83 | 5.72 |
| Brian Wilson |   | cl | 25 | .529 | 66 | .227 | 30 | .323 | 31 | .333 | 5.7 | 2.1 | 1.94 | 1.87 |
| C.J. Wilson* | ROK | mr | 26 | .602 | 179 | .257 | 102 | .358 | 108 | .379 | 22.4 | 2.9 | 2.66 | 3.01 |
| Matt Wise |   | mr | 31 | .771 | 170 | .329 | 110 | .466 | 111 | .470 | 32.2 | 5.3 | 4.86 | 4.49 |
| Jay Witasick |   | mr | 34 | .812 | 98 | .296 | 74 | .507 | 75 | .514 | 20.1 | 5.8 | 5.19 | 5.72 |
| Randy Wolf* | CCL | sp | 30 | .762 | 309 | .324 | 208 | .454 | 214 | .467 | 59.8 | 5.2 | 4.71 | 4.52 |
| Ross Wolf |   | mr | 24 | 1.103 | 52 | .385 | 44 | .667 | 45 | .682 | 18.1 | 12.8 | 11.86 | 11.46 |
| Brian Wolfe | OTR | mr | 26 | .643 | 136 | .228 | 69 | .397 | 71 | .408 | 15.3 | 3.1 | 2.73 | 2.52 |
| Kerry Wood | MUL | mr | 30 | .609 | 64 | .281 | 39 | .386 | 39 | .386 | 8.2 | 3.0 | 2.74 | 2.49 |
| Mike Wood |   | mr | 27 | .906 | 181 | .326 | 128 | .547 | 132 | .564 | 41.5 | 7.3 | 6.63 | 6.57 |
| Jake Woods* |   | mr | 25 | .688 | 36 | .222 | 21 | .429 | 22 | .449 | 5.6 | 4.6 | 4.25 | 4.41 |
| Chase Wright* |   | sp | 24 | 1.115 | 28 | .250 | 35 | .714 | 37 | .755 | 12.3 | 11.0 | 9.92 | 10.50 |
| Jamey Wright |   | mr | 32 | .743 | 239 | .276 | 147 | .445 | 152 | .461 | 36.7 | 4.3 | 3.87 | 4.44 |
| Jaret Wright |   | sp | 31 | .899 | 31 | .355 | 27 | .563 | 27 | .563 | 8.5 | 7.9 | 6.63 | 7.40 |
| Michael Wuertz | BT | mr | 28 | .712 | 190 | .295 | 142 | .455 | 142 | .455 | 36.2 | 4.5 | 4.06 | 3.68 |
| Tyler Yates |   | mr | 29 | .738 | 185 | .314 | 133 | .452 | 136 | .463 | 37.6 | 5.1 | 4.61 | 4.02 |
| Shane Youman* |   | sp | 27 | .813 | 196 | .306 | 119 | .463 | 123 | .479 | 37.2 | 5.9 | 5.25 | 5.02 |
| Chris Young | COP | sp | 28 | .578 | 449 | .241 | 255 | .362 | 262 | .372 | 61.7 | 3.2 | 2.89 | 2.35 |
| Mike Zagurski* |   | mr | 24 | .818 | 65 | .338 | 50 | .495 | 51 | .505 | 14.8 | 6.0 | 5.61 | 5.75 |
| Carlos Zambrano | CCL | sp | 26 | .701 | 610 | .269 | 399 | .431 | 413 | .446 | 101.0 | 4.2 | 3.78 | 3.88 |
| Victor Zambrano |   | mr | 31 | 1.044 | 76 | .342 | 75 | .600 | 80 | .640 | 28.1 | 11.0 | 9.88 | 11.33 |
| Mauro Zarate |   | mr | 24 | 1.183 | 22 | .364 | 22 | .733 | 23 | .767 | 9.3 | 14.8 | 15.11 | 15.61 |
| Barry Zito* | EDG | sp | 29 | .725 | 608 | .260 | 385 | .453 | 389 | .458 | 99.6 | 4.5 | 4.10 | 3.91 |
| Joel Zumaya |   | mr | 22 | .586 | 94 | .213 | 53 | .373 | 54 | .380 | 11.7 | 3.1 | 2.83 | 2.68 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% |
| David Aardsma | BT | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Winston Abreu |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Jeremy Accardo | CRH | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Manny Acosta |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Jon Adkins |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeremy Affeldt* | CRH | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 2 | .071 |
| Jonathan Albaladejo |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Matt Albers |   | sp | 24 | 18 | 0 | .000 | 0 | 8 | .444 | 66 | 3.7 | 15 | 4 | .267 |
| Antonio Alfonseca |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 8 | .533 |
| Greg Aquino |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Alberto Arias |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Tony Armas |   | mr | 29 | 15 | 0 | .000 | 0 | 6 | .400 | 94 | 6.3 | 17 | 2 | .118 |
| Bronson Arroyo | BT | sp | 30 | 34 | 1 | .029 | 0 | 22 | .647 | 135 | 4.0 | 15 | 6 | .400 |
| Jose Ascanio |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Scott Atchison |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 |
| Luis Ayala |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 |
| Brandon Backe |   | sp | 29 | 5 | 0 | .000 | 0 | 3 | .600 | 32 | 6.4 | 1 | 0 | .000 |
| Mike Bacsik* |   | sp | 29 | 20 | 0 | .000 | 0 | 8 | .400 | 86 | 4.3 | 23 | 5 | .217 |
| Cha Seung Baek | EDG | sp | 27 | 12 | 1 | .083 | 0 | 5 | .417 | 75 | 6.3 | 13 | 5 | .385 |
| Danys Baez |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 8 | .533 |
| Homer Bailey | CCL | sp | 21 | 9 | 0 | .000 | 0 | 1 | .111 | 49 | 5.4 | 9 | 5 | .556 |
| Scott Baker | BON | sp | 25 | 23 | 2 | .087 | 1 | 12 | .522 | 101 | 4.4 | 14 | 2 | .143 |
| John Bale* | BON | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 |
| Grant Balfour |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 |
| Josh Banks |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 1 | 1 | 1.000 |
| Brian Bannister | EDG | sp | 26 | 27 | 1 | .037 | 0 | 15 | .556 | 126 | 4.7 | 11 | 4 | .364 |
| Daniel Barone |   | mr | 24 | 6 | 0 | .000 | 0 | 0 | .000 | 21 | 3.5 | 7 | 1 | .143 |
| Kevin Barry |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Miguel Batista |   | sp | 36 | 32 | 0 | .000 | 0 | 18 | .563 | 127 | 4.0 | 29 | 9 | .310 |
| Denny Bautista |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 12 | 12.0 | 7 | 3 | .429 |
| Jonah Bayliss |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Yorman Bazardo |   | mr | 22 | 2 | 0 | .000 | 0 | 1 | .500 | 12 | 6.0 | 2 | 0 | .000 |
| Colter Bean |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Josh Beckett | Pal | sp | 27 | 30 | 1 | .033 | 0 | 20 | .667 | 186 | 6.2 | 7 | 0 | .000 |
| Erik Bedard* | GEO | sp | 28 | 28 | 1 | .036 | 1 | 21 | .750 | 130 | 4.6 | 10 | 3 | .300 |
| Joe Beimel* | WIZ | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 8 | .250 |
| Matt Belisle | CCL | sp | 27 | 30 | 1 | .033 | 0 | 11 | .367 | 165 | 5.5 | 13 | 6 | .462 |
| Heath Bell | MUL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Rob Bell |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 |
| Armando Benitez |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 |
| Jeff Bennett |   | sp | 27 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 2 | 0 | .000 |
| Joaquin Benoit | OTR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 |
| Jason Bergmann |   | sp | 25 | 21 | 0 | .000 | 0 | 10 | .476 | 89 | 4.2 | 13 | 4 | .308 |
| Rafael Betancourt | GEO | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 |
| Chad Billingsley | TON | mr | 22 | 20 | 1 | .050 | 0 | 9 | .450 | 97 | 4.8 | 16 | 2 | .125 |
| Kurt Birkins* |   | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 10 | 5.0 | 12 | 3 | .250 |
| Joe Bisenius |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Nick Blackburn |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Travis Blackley* |   | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 10 | 5.0 | 1 | 0 | .000 |
| Joe Blanton | BON | sp | 26 | 34 | 3 | .088 | 1 | 20 | .588 | 156 | 4.6 | 22 | 9 | .409 |
| Jerry Blevins* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Jeremy Bonderman |   | sp | 24 | 28 | 0 | .000 | 0 | 15 | .536 | 153 | 5.5 | 17 | 9 | .529 |
| Boof Bonser |   | sp | 25 | 30 | 0 | .000 | 0 | 11 | .367 | 124 | 4.1 | 21 | 10 | .476 |
| Chris Booker |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chris Bootcheck |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 |
| Dave Borkowski |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 |
| Joe Borowski | EDG | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Micah Bowie* |   | mr | 32 | 8 | 0 | .000 | 0 | 2 | .250 | 41 | 5.1 | 22 | 8 | .364 |
| Blaine Boyer |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Dallas Braden* |   | sp | 23 | 14 | 0 | .000 | 0 | 2 | .143 | 53 | 3.8 | 9 | 4 | .444 |
| Chad Bradford | MID | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 13 | .351 |
| Ryan Braun |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 |
| Bill Bray* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Yhency Brazoban |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Chris Britton |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Lance Broadway |   | mr | 23 | 1 | 0 | .000 | 0 | 1 | 1.000 | 10 | 10.0 | 1 | 1 | 1.000 |
| Doug Brocail | CCL | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 4 | .211 |
| Jim Brower |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Andrew Brown | EDG | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Jonathan Broxton | CCL | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Brian Bruney |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 14 | .378 |
| Clay Buchholz |   | sp | 22 | 3 | 1 | .333 | 1 | 2 | .667 | 19 | 6.3 | 2 | 0 | .000 |
| Taylor Buchholz | TON | mr | 25 | 8 | 0 | .000 | 0 | 3 | .375 | 37 | 4.6 | 15 | 6 | .400 |
| Billy Buckner |   | sp | 23 | 5 | 0 | .000 | 0 | 1 | .200 | 18 | 3.6 | 2 | 1 | .500 |
| Mark Buehrle* | GEO | sp | 28 | 30 | 3 | .100 | 1 | 20 | .667 | 127 | 4.2 | 18 | 11 | .611 |
| Ryan Bukvich |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 8 | .229 |
| Jason Bulger |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Bryan Bullington |   | sp | 26 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 1 | 0 | .000 |
| Ambiorix Burgos |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| A.J. Burnett | TON | sp | 30 | 25 | 2 | .080 | 0 | 17 | .680 | 114 | 4.6 | 16 | 5 | .313 |
| Brian Burres* |   | mr | 26 | 17 | 0 | .000 | 0 | 6 | .353 | 77 | 4.5 | 23 | 12 | .522 |
| Jared Burton | MAD | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 |
| Dave Bush | OTR | sp | 27 | 31 | 0 | .000 | 0 | 15 | .484 | 145 | 4.7 | 20 | 8 | .400 |
| Paul Byrd |   | sp | 36 | 31 | 2 | .065 | 2 | 15 | .484 | 168 | 5.4 | 32 | 8 | .250 |
| Tim Byrdak* | EDG | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 |
| Daniel Cabrera |   | sp | 26 | 34 | 1 | .029 | 0 | 14 | .412 | 172 | 5.1 | 18 | 10 | .556 |
| Fernando Cabrera |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 11 | .647 |
| Matt Cain | LON | sp | 22 | 32 | 1 | .031 | 0 | 22 | .688 | 101 | 3.2 | 18 | 10 | .556 |
| Kiko Calero |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 |
| Carmen Cali* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 |
| Kevin Cameron | LON | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 11 | .550 |
| Shawn Camp |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 6 | .222 |
| Jorge Campillo |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Jose Capellan |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Matt Capps | MUL | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Chris Capuano* |   | sp | 28 | 25 | 0 | .000 | 0 | 6 | .240 | 92 | 3.7 | 25 | 16 | .640 |
| Buddy Carlyle |   | sp | 29 | 20 | 0 | .000 | 0 | 6 | .300 | 113 | 5.7 | 13 | 2 | .154 |
| Fausto Carmona | GEO | sp | 23 | 32 | 2 | .063 | 1 | 26 | .813 | 163 | 5.1 | 13 | 3 | .231 |
| Chris Carpenter | CRH | sp | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 0 | 0 | .000 |
| Hector Carrasco |   | mr | 37 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 |
| Marcos Carvajal |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Santiago Casilla | OTR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 |
| Jack Cassel |   | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 20 | 5.0 | 8 | 3 | .375 |
| Fabio Castro* |   | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 6 | 2 | .333 |
| Troy Cate* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Andy Cavazos |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 |
| Gustavo Chacin* |   | sp | 26 | 5 | 0 | .000 | 0 | 2 | .400 | 25 | 5.0 | 4 | 3 | .750 |
| Shawn Chacon |   | mr | 29 | 4 | 0 | .000 | 0 | 1 | .250 | 24 | 6.0 | 29 | 8 | .276 |
| Joba Chamberlain |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Bruce Chen* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Rocky Cherry |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Matt Chico* |   | sp | 24 | 31 | 0 | .000 | 0 | 10 | .323 | 142 | 4.6 | 29 | 9 | .310 |
| Randy Choate* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Vinnie Chulk |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 7 | .368 |
| Darren Clarke |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Roger Clemens | ROK | sp | 44 | 17 | 0 | .000 | 0 | 10 | .588 | 80 | 4.7 | 9 | 4 | .444 |
| Tyler Clippard |   | sp | 22 | 6 | 0 | .000 | 0 | 1 | .167 | 53 | 8.8 | 2 | 0 | .000 |
| Todd Coffey |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 |
| Willie Collazo* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Jesus Colome |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 |
| Bartolo Colon |   | sp | 34 | 18 | 0 | .000 | 0 | 8 | .444 | 106 | 5.9 | 8 | 6 | .750 |
| Steve Colyer* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 |
| Clay Condrey |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 |
| Jose Contreras |   | sp | 35 | 30 | 2 | .067 | 2 | 12 | .400 | 136 | 4.5 | 24 | 13 | .542 |
| Aaron Cook | MAD | sp | 28 | 25 | 2 | .080 | 0 | 15 | .600 | 123 | 4.9 | 8 | 5 | .625 |
| Tim Corcoran |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 |
| Chad Cordero |   | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Francisco Cordero | CRH | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Bryan Corey |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Lance Cormier |   | sp | 26 | 9 | 0 | .000 | 0 | 2 | .222 | 37 | 4.1 | 5 | 1 | .200 |
| Rheal Cormier* |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Manny Corpas | MUL | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Kevin Correia | MUL | mr | 26 | 8 | 0 | .000 | 0 | 3 | .375 | 33 | 4.1 | 34 | 7 | .206 |
| Neal Cotts* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Jon Coutlangus* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 48 | 11 | .229 |
| Jesse Crain |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Juan Cruz | TON | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 |
| John Danks* | EDG | sp | 22 | 26 | 0 | .000 | 0 | 8 | .308 | 95 | 3.7 | 24 | 3 | .125 |
| Dave Davidson* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Kyle Davies |   | sp | 23 | 28 | 0 | .000 | 0 | 7 | .250 | 129 | 4.6 | 25 | 10 | .400 |
| Doug Davis* |   | sp | 31 | 33 | 0 | .000 | 0 | 19 | .576 | 140 | 4.2 | 18 | 3 | .167 |
| Jason Davis |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 |
| Kane Davis |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Dewon Day |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 |
| Jordan De Jong |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Eulogio De La Cruz |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jorge De La Rosa* |   | sp | 26 | 23 | 0 | .000 | 0 | 8 | .348 | 129 | 5.6 | 27 | 12 | .444 |
| Manny Delcarmen | GEO | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 2 | .111 |
| Ryan Dempster | CRH | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Julio DePaula |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Matt DeSalvo |   | sp | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 33 | 5.5 | 13 | 2 | .154 |
| Elmer Dessens |   | mr | 36 | 5 | 0 | .000 | 0 | 1 | .200 | 45 | 9.0 | 5 | 3 | .600 |
| Ross Detwiler* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Joey Devine |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Lenny DiNardo* |   | sp | 27 | 20 | 0 | .000 | 0 | 7 | .350 | 106 | 5.3 | 21 | 9 | .429 |
| Scott Dohmann |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Brendan Donnelly |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 1 | .063 |
| Octavio Dotel |   | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Dennis Dove |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Scott Downs* | EDG | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 5 | .109 |
| Cory Doyne |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Travis Driskill |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Justin Duchscherer | COP | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Brandon Duckworth |   | mr | 31 | 3 | 0 | .000 | 0 | 1 | .333 | 7 | 2.3 | 19 | 8 | .421 |
| Zach Duke* |   | sp | 24 | 19 | 0 | .000 | 0 | 7 | .368 | 93 | 4.9 | 11 | 3 | .273 |
| Phil Dumatrait* |   | sp | 25 | 6 | 0 | .000 | 0 | 1 | .167 | 30 | 5.0 | 7 | 6 | .857 |
| Chad Durbin |   | sp | 29 | 19 | 0 | .000 | 0 | 6 | .316 | 106 | 5.6 | 26 | 10 | .385 |
| J.D. Durbin |   | sp | 25 | 10 | 1 | .100 | 1 | 4 | .400 | 83 | 8.3 | 12 | 3 | .250 |
| Adam Eaton |   | sp | 29 | 30 | 0 | .000 | 0 | 8 | .267 | 150 | 5.0 | 24 | 10 | .417 |
| Scott Elarton |   | sp | 31 | 9 | 0 | .000 | 0 | 0 | .000 | 54 | 6.0 | 12 | 8 | .667 |
| Alan Embree* | BON | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 |
| John Ennis |   | cl | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 5 | 3 | .600 |
| Kelvim Escobar | BON | sp | 31 | 30 | 3 | .100 | 1 | 20 | .667 | 181 | 6.0 | 13 | 4 | .308 |
| Dana Eveland* |   | mr | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 13 | 13.0 | 3 | 1 | .333 |
| Scott Eyre* |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 |
| Willie Eyre |   | mr | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 14 | 7.0 | 9 | 2 | .222 |
| Brian Falkenborg |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Kyle Farnsworth |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 |
| Ryan Feierabend* |   | sp | 21 | 9 | 0 | .000 | 0 | 0 | .000 | 35 | 3.9 | 7 | 3 | .429 |
| Scott Feldman | MID | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 |
| Pedro Feliciano* | MAD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 11 | .250 |
| Nate Field |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Randy Flores* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 7 | .206 |
| Ron Flores* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 |
| Gavin Floyd | TON | sp | 24 | 10 | 0 | .000 | 0 | 6 | .600 | 29 | 2.9 | 9 | 1 | .111 |
| Josh Fogg |   | sp | 30 | 29 | 0 | .000 | 0 | 12 | .414 | 150 | 5.2 | 14 | 7 | .500 |
| Casey Fossum* |   | mr | 29 | 10 | 0 | .000 | 0 | 3 | .300 | 50 | 5.0 | 29 | 9 | .310 |
| Jeff Francis* | MAD | sp | 26 | 34 | 1 | .029 | 1 | 19 | .559 | 179 | 5.3 | 17 | 9 | .529 |
| Frank Francisco | EDG | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 6 | .231 |
| Ryan Franklin | LON | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Jason Frasor | MID | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 |
| Brian Fuentes* | CCL | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Aaron Fultz* | MAD | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 4 | .133 |
| Kason Gabbard* | CRH | sp | 25 | 15 | 1 | .067 | 1 | 6 | .400 | 120 | 8.0 | 20 | 6 | .300 |
| Eric Gagne | GEO | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Armando Galarraga |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 0 | 0 | .000 |
| Sean Gallagher |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Yovani Gallardo | LON | sp | 21 | 17 | 0 | .000 | 0 | 12 | .706 | 90 | 5.3 | 5 | 1 | .200 |
| Anderson Garcia |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Freddy Garcia |   | sp | 31 | 11 | 0 | .000 | 0 | 4 | .364 | 60 | 5.5 | 19 | 8 | .421 |
| Harvey Garcia |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Lee Gardner | MAD | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 |
| Jon Garland | COP | sp | 27 | 32 | 2 | .063 | 1 | 21 | .656 | 135 | 4.2 | 16 | 8 | .500 |
| Matt Garza | GEO | sp | 23 | 15 | 0 | .000 | 0 | 6 | .400 | 64 | 4.3 | 15 | 7 | .467 |
| Chad Gaudin |   | sp | 24 | 34 | 1 | .029 | 0 | 15 | .441 | 171 | 5.0 | 34 | 9 | .265 |
| Geoff Geary |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 11 | .524 |
| Justin Germano | CCL | sp | 24 | 23 | 0 | .000 | 0 | 12 | .522 | 83 | 3.6 | 16 | 8 | .500 |
| Dan Giese |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Tom Glavine* | WIZ | sp | 41 | 34 | 1 | .029 | 1 | 23 | .676 | 175 | 5.1 | 20 | 11 | .550 |
| Gary Glover |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 |
| Jimmy Gobble* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 48 | 5 | .104 |
| Edgar Gonzalez |   | mr | 24 | 12 | 0 | .000 | 0 | 2 | .167 | 50 | 4.2 | 5 | 0 | .000 |
| Enrique Gonzalez |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Gonzalez* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Tom Gordon |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 |
| Tom Gorzelanny* | LON | sp | 24 | 32 | 1 | .031 | 1 | 19 | .594 | 143 | 4.5 | 16 | 4 | .250 |
| Mike Gosling* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 |
| John Grabow* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 11 | .458 |
| Sean Green |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 51 | 7 | .137 |
| Kevin Gregg | BT | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Zack Greinke | COP | mr | 23 | 14 | 0 | .000 | 0 | 4 | .286 | 47 | 3.4 | 19 | 5 | .263 |
| Jason Grilli | COP | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 10 | .333 |
| Lee Gronkiewicz |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Eddie Guardado* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Matt Guerrier | MID | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 |
| Jeremy Guthrie | MID | sp | 28 | 26 | 0 | .000 | 0 | 17 | .654 | 115 | 4.4 | 12 | 1 | .083 |
| Juan Gutierrez |   | mr | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 18 | 6.0 | 0 | 0 | .000 |
| Angel Guzman |   | mr | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 16 | 5.3 | 3 | 2 | .667 |
| Marc Gwyn |   | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Charlie Haeger |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Roy Halladay | ROK | sp | 30 | 31 | 7 | .226 | 1 | 21 | .677 | 173 | 5.6 | 14 | 10 | .714 |
| Cole Hamels* | BT | sp | 23 | 28 | 2 | .071 | 0 | 16 | .571 | 149 | 5.3 | 5 | 0 | .000 |
| Jason Hammel | EDG | sp | 24 | 14 | 0 | .000 | 0 | 3 | .214 | 71 | 5.1 | 6 | 3 | .500 |
| Justin Hampson* | CCL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 |
| Josh Hancock |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Joel Hanrahan | CCL | sp | 25 | 11 | 0 | .000 | 0 | 2 | .182 | 62 | 5.6 | 8 | 1 | .125 |
| Devern Hansack |   | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| J.A. Happ* |   | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 0 | 0 | .000 |
| Aaron Harang | GEO | sp | 29 | 34 | 2 | .059 | 1 | 20 | .588 | 180 | 5.3 | 10 | 4 | .400 |
| Rich Harden | COP | sp | 25 | 4 | 0 | .000 | 0 | 3 | .750 | 15 | 3.8 | 3 | 1 | .333 |
| Dan Haren | LON | sp | 26 | 34 | 0 | .000 | 0 | 28 | .824 | 156 | 4.6 | 18 | 5 | .278 |
| Tim Harikkala |   | sp | 35 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 2 | 0 | .000 |
| Kevin Hart |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| LaTroy Hawkins | BT | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Aaron Heilman | WIZ | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 |
| Mark Hendrickson* | MUL | mr | 33 | 15 | 0 | .000 | 0 | 2 | .133 | 65 | 4.3 | 21 | 7 | .333 |
| Sean Henn* |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 17 | 5 | .294 |
| Brad Hennessey |   | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 |
| Clay Hensley |   | sp | 27 | 9 | 0 | .000 | 0 | 2 | .222 | 49 | 5.4 | 10 | 3 | .300 |
| Matt Herges | LON | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Felix Hernandez | ROK | sp | 21 | 30 | 1 | .033 | 1 | 15 | .500 | 157 | 5.2 | 16 | 4 | .250 |
| Livan Hernandez |   | sp | 32 | 33 | 1 | .030 | 0 | 19 | .576 | 144 | 4.4 | 8 | 3 | .375 |
| Orlando Hernandez | Pal | sp | 37 | 24 | 0 | .000 | 0 | 17 | .708 | 112 | 4.7 | 10 | 1 | .100 |
| Roberto Hernandez |   | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 |
| Yoel Hernandez |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Rich Hill* | BT | sp | 27 | 32 | 0 | .000 | 0 | 17 | .531 | 109 | 3.4 | 8 | 1 | .125 |
| Shawn Hill | WIZ | sp | 26 | 16 | 0 | .000 | 0 | 11 | .688 | 59 | 3.7 | 7 | 3 | .429 |
| Jason Hirsh | WIZ | sp | 25 | 19 | 1 | .053 | 0 | 10 | .526 | 87 | 4.6 | 14 | 3 | .214 |
| Luke Hochevar |   | mr | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 2 | 0 | .000 |
| Jim Hoey |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Trevor Hoffman | Pal | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| D.J. Houlton |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| J.P. Howell* | MID | sp | 24 | 10 | 0 | .000 | 0 | 3 | .300 | 46 | 4.6 | 5 | 3 | .600 |
| Bob Howry | COP | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 |
| Jon Huber |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 |
| Luke Hudson |   | sp | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 1 | 0 | .000 |
| Tim Hudson | GEO | sp | 31 | 34 | 1 | .029 | 1 | 25 | .735 | 191 | 5.6 | 18 | 8 | .444 |
| Phil Hughes | COP | sp | 21 | 13 | 0 | .000 | 0 | 5 | .385 | 88 | 6.8 | 10 | 5 | .500 |
| Eric Hull |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Philip Humber |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 2 | 2 | 1.000 |
| Kei Igawa* |   | sp | 27 | 12 | 0 | .000 | 0 | 1 | .083 | 75 | 6.3 | 9 | 3 | .333 |
| Jason Isringhausen | Pal | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Edwin Jackson |   | sp | 23 | 31 | 1 | .032 | 1 | 14 | .452 | 133 | 4.3 | 26 | 12 | .462 |
| Chuck James* |   | sp | 25 | 30 | 0 | .000 | 0 | 11 | .367 | 146 | 4.9 | 17 | 7 | .412 |
| Casey Janssen | OTR | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 |
| Bobby Jenks | OTR | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jason Jennings |   | sp | 28 | 18 | 0 | .000 | 0 | 6 | .333 | 66 | 3.7 | 7 | 4 | .571 |
| Kelvin Jimenez |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 8 | .800 |
| Ubaldo Jimenez | TON | sp | 23 | 15 | 0 | .000 | 0 | 9 | .600 | 71 | 4.7 | 8 | 5 | .625 |
| Jim Johnson |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Josh Johnson | LON | sp | 23 | 4 | 0 | .000 | 0 | 0 | .000 | 10 | 2.5 | 1 | 0 | .000 |
| Randy Johnson* | ROK | sp | 43 | 10 | 0 | .000 | 0 | 6 | .600 | 42 | 4.2 | 5 | 3 | .600 |
| Tyler Johnson* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 |
| Greg Jones |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Todd Jones | MUL | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Jorge Julio |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 |
| Jair Jurrjens |   | sp | 21 | 7 | 0 | .000 | 0 | 1 | .143 | 33 | 4.7 | 3 | 0 | .000 |
| Jeff Karstens |   | mr | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 8 | 2.7 | 6 | 3 | .500 |
| Scott Kazmir* | GEO | sp | 23 | 34 | 0 | .000 | 0 | 19 | .559 | 158 | 4.6 | 14 | 7 | .500 |
| Randy Keisler* |   | sp | 31 | 3 | 0 | .000 | 0 | 1 | .333 | 15 | 5.0 | 1 | 0 | .000 |
| Kyle Kendrick |   | sp | 22 | 20 | 0 | .000 | 0 | 13 | .650 | 129 | 6.4 | 4 | 1 | .250 |
| Ian Kennedy |   | sp | 22 | 3 | 0 | .000 | 0 | 2 | .667 | 13 | 4.3 | 1 | 0 | .000 |
| Joe Kennedy* |   | mr | 28 | 16 | 0 | .000 | 0 | 8 | .500 | 56 | 3.5 | 22 | 8 | .364 |
| Logan Kensing |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Bobby Keppel |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Byung-Hyun Kim |   | sp | 28 | 22 | 0 | .000 | 0 | 6 | .273 | 133 | 6.0 | 25 | 6 | .240 |
| Ray King* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 6 | .140 |
| Steve Kline* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 13 | .361 |
| Dan Kolb |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Shane Komine |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Koplove |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| John Koronka* |   | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 2 | 1.0 | 4 | 3 | .750 |
| Hong-Chih Kuo* | Pal | sp | 25 | 6 | 0 | .000 | 0 | 2 | .333 | 21 | 3.5 | 6 | 3 | .500 |
| Masumi Kuwata |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| John Lackey | COP | sp | 28 | 33 | 2 | .061 | 2 | 24 | .727 | 146 | 4.4 | 11 | 2 | .182 |
| Aaron Laffey* | EDG | sp | 22 | 9 | 0 | .000 | 0 | 1 | .111 | 48 | 5.3 | 8 | 4 | .500 |
| John Lannan* |   | sp | 22 | 6 | 0 | .000 | 0 | 2 | .333 | 27 | 4.5 | 5 | 2 | .400 |
| Juan Lara* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Brian Lawrence |   | sp | 31 | 6 | 0 | .000 | 0 | 1 | .167 | 33 | 5.5 | 4 | 0 | .000 |
| Brandon League |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Wilfredo Ledezma* |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 12 | 12.0 | 16 | 5 | .313 |
| Cliff Lee* | MID | sp | 28 | 16 | 1 | .063 | 0 | 6 | .375 | 103 | 6.4 | 9 | 5 | .556 |
| Jon Leicester |   | sp | 28 | 5 | 1 | .200 | 0 | 1 | .200 | 24 | 4.8 | 8 | 6 | .750 |
| Anthony Lerew |   | sp | 24 | 3 | 0 | .000 | 0 | 1 | .333 | 8 | 2.7 | 1 | 0 | .000 |
| Jon Lester* | EDG | sp | 23 | 11 | 0 | .000 | 0 | 5 | .455 | 67 | 6.1 | 6 | 0 | .000 |
| Colby Lewis |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 7 | 2 | .286 |
| Jensen Lewis |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 |
| Brad Lidge | Pal | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Jon Lieber | MUL | sp | 37 | 12 | 1 | .083 | 1 | 5 | .417 | 50 | 4.2 | 7 | 2 | .286 |
| Ted Lilly* | OTR | sp | 31 | 34 | 0 | .000 | 0 | 20 | .588 | 179 | 5.3 | 10 | 1 | .100 |
| Tim Lincecum | WIZ | sp | 23 | 24 | 0 | .000 | 0 | 16 | .667 | 112 | 4.7 | 16 | 7 | .438 |
| Matt Lindstrom | MUL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 |
| Scott Linebrink |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Jesse Litsch | EDG | sp | 22 | 20 | 0 | .000 | 0 | 12 | .600 | 81 | 4.1 | 15 | 5 | .333 |
| Wes Littleton |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 |
| Bobby Livingston* |   | sp | 24 | 10 | 0 | .000 | 0 | 4 | .400 | 58 | 5.8 | 4 | 3 | .750 |
| Radhames Liz |   | mr | 24 | 4 | 0 | .000 | 0 | 0 | .000 | 23 | 5.8 | 8 | 0 | .000 |
| Esteban Loaiza |   | sp | 35 | 7 | 0 | .000 | 0 | 3 | .429 | 29 | 4.1 | 8 | 0 | .000 |
| Kameron Loe |   | sp | 25 | 23 | 0 | .000 | 0 | 9 | .391 | 94 | 4.1 | 19 | 6 | .316 |
| Adam Loewen* |   | sp | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 27 | 4.5 | 6 | 3 | .500 |
| Boone Logan* |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 47 | 6 | .128 |
| Kyle Lohse | COP | sp | 28 | 32 | 2 | .063 | 1 | 15 | .469 | 140 | 4.4 | 23 | 7 | .304 |
| Braden Looper | MAD | sp | 32 | 30 | 0 | .000 | 0 | 18 | .600 | 139 | 4.6 | 15 | 10 | .667 |
| Aquilino Lopez |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Javier Lopez* | OTR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 5 | .156 |
| Rodrigo Lopez | CCL | sp | 31 | 14 | 0 | .000 | 0 | 8 | .571 | 72 | 5.1 | 9 | 2 | .222 |
| Derek Lowe | BON | sp | 34 | 32 | 3 | .094 | 0 | 19 | .594 | 147 | 4.6 | 16 | 4 | .250 |
| Mark Lowe |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Noah Lowry* |   | sp | 26 | 26 | 1 | .038 | 0 | 13 | .500 | 119 | 4.6 | 17 | 3 | .176 |
| Ruddy Lugo |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 |
| Brandon Lyon | Pal | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Mike MacDougal |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 50 | 16 | .320 |
| Greg Maddux | Pal | sp | 41 | 34 | 1 | .029 | 0 | 18 | .529 | 157 | 4.6 | 19 | 7 | .368 |
| Ryan Madson | CCL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 |
| Ron Mahay* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 4 | .143 |
| Paul Maholm* |   | sp | 25 | 29 | 2 | .069 | 1 | 12 | .414 | 119 | 4.1 | 17 | 7 | .412 |
| John Maine | BT | sp | 26 | 32 | 1 | .031 | 1 | 17 | .531 | 178 | 5.6 | 24 | 7 | .292 |
| Gary Majewski |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 12 | .522 |
| Shaun Marcum | COP | sp | 25 | 25 | 0 | .000 | 0 | 15 | .600 | 119 | 4.8 | 11 | 5 | .455 |
| Carlos Marmol | WIZ | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| Mike Maroth* |   | sp | 29 | 20 | 0 | .000 | 0 | 5 | .250 | 122 | 6.1 | 22 | 7 | .318 |
| Jason Marquis | MUL | sp | 28 | 33 | 1 | .030 | 1 | 15 | .455 | 180 | 5.5 | 22 | 6 | .273 |
| Jay Marshall* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 5 | .208 |
| Sean Marshall* | LON | sp | 24 | 19 | 0 | .000 | 0 | 10 | .526 | 78 | 4.1 | 13 | 4 | .308 |
| Damaso Marte* | WIZ | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 |
| Tom Martin* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Carlos Martinez |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Pedro Martinez |   | sp | 35 | 5 | 0 | .000 | 0 | 2 | .400 | 26 | 5.2 | 0 | 0 | .000 |
| Nick Masset |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 26 | 8 | .308 |
| Tom Mastny |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 |
| Julio Mateo |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Daisuke Matsuzaka | OTR | sp | 26 | 32 | 1 | .031 | 0 | 18 | .563 | 158 | 4.9 | 12 | 7 | .583 |
| Marcus McBeth |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 |
| Macay McBride* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 8 | .242 |
| Brandon McCarthy | EDG | sp | 23 | 22 | 0 | .000 | 0 | 9 | .409 | 107 | 4.9 | 10 | 3 | .300 |
| Zach McClellan |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Seth McClung |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 |
| Dustin McGowan | OTR | sp | 25 | 27 | 2 | .074 | 1 | 18 | .667 | 117 | 4.3 | 11 | 3 | .273 |
| Marty McLeary |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mark McLemore* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 |
| Gil Meche | CRH | sp | 28 | 34 | 1 | .029 | 0 | 23 | .676 | 132 | 3.9 | 19 | 1 | .053 |
| Brandon Medders |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 |
| Jonathan Meloan |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Luis Mendoza |   | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 26 | 8.7 | 3 | 0 | .000 |
| Cla Meredith |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 |
| Jose Mesa |   | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 |
| Randy Messenger |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Dan Meyer* |   | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 18 | 6.0 | 4 | 3 | .750 |
| Andrew Miller* | GEO | sp | 22 | 13 | 0 | .000 | 0 | 4 | .308 | 81 | 6.2 | 10 | 3 | .300 |
| Jason Miller* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Justin Miller |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| Matt Miller |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Trever Miller* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 45 | 8 | .178 |
| Wade Miller |   | sp | 30 | 3 | 0 | .000 | 0 | 0 | .000 | 16 | 5.3 | 3 | 1 | .333 |
| Kevin Millwood |   | sp | 32 | 31 | 0 | .000 | 0 | 14 | .452 | 142 | 4.6 | 16 | 5 | .313 |
| Eric Milton* |   | sp | 31 | 6 | 0 | .000 | 0 | 1 | .167 | 22 | 3.7 | 4 | 0 | .000 |
| Zach Miner |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 13 | 1 | .077 |
| Patrick Misch* |   | mr | 25 | 4 | 0 | .000 | 0 | 0 | .000 | 14 | 3.5 | 7 | 1 | .143 |
| Sergio Mitre |   | sp | 26 | 27 | 0 | .000 | 0 | 11 | .407 | 126 | 4.7 | 23 | 3 | .130 |
| Brian Moehler |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Franklin Morales* |   | sp | 21 | 8 | 0 | .000 | 0 | 2 | .250 | 48 | 6.0 | 7 | 1 | .143 |
| Juan Morillo |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Matt Morris |   | sp | 32 | 32 | 3 | .094 | 0 | 15 | .469 | 167 | 5.2 | 18 | 6 | .333 |
| Brandon Morrow | CRH | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 12 | .308 |
| Dustin Moseley |   | mr | 25 | 8 | 0 | .000 | 0 | 2 | .250 | 39 | 4.9 | 28 | 6 | .214 |
| Guillermo Mota |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 |
| Jamie Moyer* |   | sp | 44 | 33 | 1 | .030 | 0 | 18 | .545 | 174 | 5.3 | 24 | 11 | .458 |
| Peter Moylan | MAD | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Edward Mujica |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Mark Mulder* |   | sp | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 6 | 2.0 | 0 | 0 | .000 |
| Carlos Muniz |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Arnie Munoz* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 |
| Scott Munter |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Bill Murphy* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 |
| A.J. Murray* |   | mr | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 6 | 2 | .333 |
| Neal Musser* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 |
| Mike Mussina |   | sp | 38 | 27 | 0 | .000 | 0 | 13 | .481 | 154 | 5.7 | 17 | 5 | .294 |
| Brett Myers | CRH | cl | 26 | 3 | 0 | .000 | 0 | 1 | .333 | 14 | 4.7 | 5 | 2 | .400 |
| Mike Myers* |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 11 | .250 |
| Joe Nathan | WIZ | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Pat Neshek | BON | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 |
| Josh Newman* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Dustin Nippert |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Ricky Nolasco |   | sp | 24 | 4 | 0 | .000 | 0 | 0 | .000 | 11 | 2.8 | 0 | 0 | .000 |
| Leo Nunez |   | mr | 23 | 6 | 0 | .000 | 0 | 2 | .333 | 32 | 5.3 | 8 | 3 | .375 |
| Eric O'Flaherty* | CRH | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 19 | .442 |
| Wes Obermueller |   | mr | 30 | 7 | 0 | .000 | 0 | 2 | .286 | 34 | 4.9 | 7 | 1 | .143 |
| Tomo Ohka |   | sp | 31 | 10 | 0 | .000 | 0 | 2 | .200 | 47 | 4.7 | 12 | 7 | .583 |
| Ross Ohlendorf |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Will Ohman* | MAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 5 | .109 |
| Hideki Okajima* | COP | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Darren Oliver* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 12 | .324 |
| Scott Olsen* |   | sp | 23 | 33 | 0 | .000 | 0 | 11 | .333 | 153 | 4.6 | 30 | 7 | .233 |
| Garrett Olson* |   | sp | 23 | 7 | 0 | .000 | 0 | 0 | .000 | 31 | 4.4 | 6 | 0 | .000 |
| Ramon Ortiz |   | mr | 34 | 10 | 0 | .000 | 0 | 5 | .500 | 56 | 5.6 | 6 | 2 | .333 |
| Russ Ortiz |   | sp | 33 | 8 | 0 | .000 | 0 | 1 | .125 | 43 | 5.4 | 4 | 3 | .750 |
| Chad Orvella |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Franquelis Osoria |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 |
| Roy Oswalt | BT | sp | 29 | 32 | 1 | .031 | 0 | 21 | .656 | 150 | 4.7 | 14 | 2 | .143 |
| Akinori Otsuka |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Henry Owens |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Micah Owings |   | sp | 24 | 27 | 2 | .074 | 1 | 14 | .519 | 138 | 5.1 | 19 | 5 | .263 |
| Vicente Padilla |   | sp | 29 | 23 | 0 | .000 | 0 | 7 | .304 | 130 | 5.7 | 17 | 6 | .353 |
| Jonathan Papelbon | BON | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chan Ho Park |   | sp | 34 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 0 | 0 | .000 |
| Chad Paronto |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 |
| Manny Parra* |   | mr | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 10 | 5.0 | 0 | 0 | .000 |
| John Parrish* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 |
| John Patterson |   | sp | 29 | 7 | 0 | .000 | 0 | 1 | .143 | 16 | 2.3 | 8 | 7 | .875 |
| Troy Patton* |   | sp | 21 | 2 | 0 | .000 | 0 | 1 | .500 | 4 | 2.0 | 1 | 0 | .000 |
| Felipe Paulino |   | sp | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 0 | 0 | .000 |
| Carl Pavano |   | sp | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 17 | 8.5 | 1 | 1 | 1.000 |
| Jake Peavy | MUL | sp | 26 | 34 | 0 | .000 | 0 | 28 | .824 | 181 | 5.3 | 12 | 4 | .333 |
| Jailen Peguero |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 |
| Mike Pelfrey |   | sp | 23 | 13 | 0 | .000 | 0 | 3 | .231 | 53 | 4.1 | 13 | 3 | .231 |
| Tony Pena | LON | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 |
| Brad Penny | LON | sp | 29 | 33 | 0 | .000 | 0 | 26 | .788 | 170 | 5.2 | 13 | 4 | .308 |
| Joel Peralta | MID | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Troy Percival | OTR | mr | 37 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 4 | 1 | .250 |
| Juan Perez* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Odalis Perez* |   | sp | 30 | 26 | 0 | .000 | 0 | 8 | .308 | 106 | 4.1 | 17 | 6 | .353 |
| Oliver Perez* | BT | sp | 25 | 29 | 0 | .000 | 0 | 16 | .552 | 147 | 5.1 | 21 | 4 | .190 |
| Rafael Perez* | CRH | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 |
| Glen Perkins* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Yusmeiro Petit |   | sp | 22 | 10 | 0 | .000 | 0 | 2 | .200 | 34 | 3.4 | 8 | 3 | .375 |
| Billy Petrick |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Andy Pettitte* |   | sp | 35 | 34 | 0 | .000 | 0 | 22 | .647 | 200 | 5.9 | 19 | 7 | .368 |
| Heath Phillips* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Carmen Pignatiello* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Joel Pineiro |   | mr | 28 | 11 | 0 | .000 | 0 | 5 | .455 | 45 | 4.1 | 17 | 2 | .118 |
| Renyel Pinto* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 |
| Sidney Ponson |   | sp | 30 | 7 | 0 | .000 | 0 | 1 | .143 | 38 | 5.4 | 4 | 1 | .250 |
| Bret Prinz |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Scott Proctor |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 7 | .226 |
| J.J. Putz | MID | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chad Qualls | BON | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Aaron Rakers |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Edwar Ramirez |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 |
| Elizardo Ramirez |   | sp | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 17 | 5.7 | 0 | 0 | .000 |
| Erasmo Ramirez* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Horacio Ramirez* |   | sp | 27 | 20 | 0 | .000 | 0 | 6 | .300 | 125 | 6.3 | 22 | 10 | .455 |
| Ramon Ramirez | LON | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Stephen Randolph* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 |
| Clay Rapada* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Darrell Rasner |   | sp | 26 | 6 | 0 | .000 | 0 | 0 | .000 | 28 | 4.7 | 7 | 2 | .286 |
| Jon Rauch | TON | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Chris Ray | MID | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Tim Redding | CCL | sp | 29 | 15 | 0 | .000 | 0 | 8 | .533 | 50 | 3.3 | 12 | 3 | .250 |
| Mark Redman* |   | sp | 33 | 8 | 0 | .000 | 0 | 1 | .125 | 46 | 5.8 | 16 | 2 | .125 |
| Chris Reitsma |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 |
| Chris Resop |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Al Reyes |   | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Anthony Reyes |   | sp | 25 | 20 | 1 | .050 | 0 | 5 | .250 | 65 | 3.3 | 11 | 1 | .091 |
| Dennys Reyes* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 7 | .152 |
| Jo-Jo Reyes* |   | sp | 22 | 10 | 0 | .000 | 0 | 2 | .200 | 56 | 5.6 | 12 | 6 | .500 |
| John Rheinecker* |   | mr | 28 | 7 | 0 | .000 | 0 | 3 | .429 | 36 | 5.1 | 17 | 6 | .353 |
| Jeff Ridgway* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Juan Rincon |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 11 | .355 |
| Royce Ring* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 |
| David Riske | CRH | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 0 | .000 |
| Mariano Rivera | ROK | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Saul Rivera | BT | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 16 | .500 |
| Connor Robertson |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Nate Robertson* |   | sp | 29 | 30 | 0 | .000 | 0 | 13 | .433 | 137 | 4.6 | 22 | 6 | .273 |
| Fernando Rodney | OTR | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 |
| Francisco Rodriguez | BON | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Wandy Rodriguez* | MUL | sp | 28 | 31 | 1 | .032 | 1 | 15 | .484 | 157 | 5.1 | 12 | 7 | .583 |
| Brian Rogers |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Kenny Rogers* |   | sp | 42 | 11 | 0 | .000 | 0 | 5 | .455 | 53 | 4.8 | 4 | 1 | .250 |
| J.C. Romero* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 |
| Francisco Rosario |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Ryan Rowland-Smith* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 |
| B.J. Ryan* |   | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Jae Kuk Ryu |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Kirk Saarloos |   | mr | 28 | 3 | 0 | .000 | 0 | 0 | .000 | 17 | 5.7 | 19 | 8 | .421 |
| C.C. Sabathia* | CRH | sp | 26 | 34 | 4 | .118 | 1 | 25 | .735 | 173 | 5.1 | 4 | 0 | .000 |
| Takashi Saito | Pal | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Juan Salas |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 5 | .238 |
| Brad Salmon |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Chris Sampson |   | sp | 29 | 19 | 0 | .000 | 0 | 11 | .579 | 92 | 4.8 | 13 | 4 | .308 |
| Brian Sanches |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Anibal Sanchez | MAD | sp | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 31 | 5.2 | 2 | 0 | .000 |
| Jonathan Sanchez* |   | mr | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 10 | 2.5 | 20 | 11 | .550 |
| Romulo Sanchez |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Ervin Santana | BON | sp | 24 | 26 | 0 | .000 | 0 | 12 | .462 | 115 | 4.4 | 15 | 7 | .467 |
| Johan Santana* | ROK | sp | 28 | 33 | 1 | .030 | 1 | 21 | .636 | 142 | 4.3 | 2 | 2 | 1.000 |
| Victor Santos |   | mr | 30 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 8 | 1 | .125 |
| Dennis Sarfate |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Joe Saunders* | MID | sp | 26 | 18 | 0 | .000 | 0 | 8 | .444 | 94 | 5.2 | 12 | 2 | .167 |
| Curt Schilling | Pal | sp | 40 | 24 | 1 | .042 | 1 | 14 | .583 | 115 | 4.8 | 6 | 3 | .500 |
| Jason Schmidt |   | sp | 34 | 6 | 0 | .000 | 0 | 1 | .167 | 15 | 2.5 | 5 | 2 | .400 |
| Scott Schoeneweis* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 12 | .375 |
| Chris Schroder | CCL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 8 | .444 |
| Mike Schultz |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Rudy Seanez |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 |
| Bobby Seay* | ROK | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 2 | .069 |
| Chris Seddon* |   | sp | 23 | 4 | 0 | .000 | 0 | 0 | .000 | 22 | 5.5 | 4 | 1 | .250 |
| Zack Segovia |   | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 |
| Aaron Sele |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 |
| Jae Seo |   | sp | 30 | 10 | 0 | .000 | 0 | 2 | .200 | 55 | 5.5 | 7 | 5 | .714 |
| Dan Serafini* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Josh Sharpless |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Tom Shearn |   | sp | 29 | 6 | 0 | .000 | 0 | 4 | .667 | 35 | 5.8 | 4 | 0 | .000 |
| Ben Sheets | TON | sp | 28 | 24 | 2 | .083 | 0 | 14 | .583 | 139 | 5.8 | 6 | 2 | .333 |
| George Sherrill* | ROK | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 5 | .122 |
| James Shields | BON | sp | 25 | 31 | 1 | .032 | 0 | 20 | .645 | 138 | 4.5 | 11 | 6 | .545 |
| Scot Shields | ROK | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 |
| Brian Shouse* | OTR | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 11 | .262 |
| Paul Shuey |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 8 | .667 |
| Carlos Silva | MID | sp | 28 | 33 | 2 | .061 | 1 | 20 | .606 | 127 | 3.8 | 14 | 7 | .500 |
| Jason Simontacchi |   | sp | 33 | 13 | 0 | .000 | 0 | 4 | .308 | 54 | 4.2 | 14 | 7 | .500 |
| Andrew Sisco* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Doug Slaten* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 7 | .212 |
| Kevin Slowey |   | sp | 23 | 11 | 0 | .000 | 0 | 4 | .364 | 66 | 6.0 | 6 | 1 | .167 |
| Joe Smith | LON | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 5 | .172 |
| Matt Smith* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 |
| John Smoltz | WIZ | sp | 40 | 32 | 0 | .000 | 0 | 26 | .813 | 149 | 4.7 | 6 | 4 | .667 |
| Ian Snell |   | sp | 25 | 32 | 1 | .031 | 0 | 22 | .688 | 127 | 4.0 | 8 | 4 | .500 |
| Kyle Snyder |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 |
| Andy Sonnanstine |   | sp | 24 | 22 | 0 | .000 | 0 | 9 | .409 | 131 | 6.0 | 14 | 6 | .429 |
| Joakim Soria | BON | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Rafael Soriano | GEO | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jorge Sosa |   | mr | 30 | 14 | 0 | .000 | 0 | 7 | .500 | 56 | 4.0 | 17 | 6 | .353 |
| Jeremy Sowers* |   | sp | 24 | 13 | 0 | .000 | 0 | 5 | .385 | 51 | 3.9 | 4 | 1 | .250 |
| Justin Speier | MID | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Ryan Speier |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Levale Speigner |   | mr | 26 | 6 | 0 | .000 | 0 | 1 | .167 | 28 | 4.7 | 8 | 4 | .500 |
| Russ Springer | WIZ | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 |
| Chris Spurling |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 |
| Jason Standridge |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Jason Stanford* |   | mr | 30 | 2 | 0 | .000 | 0 | 1 | .500 | 9 | 4.5 | 9 | 5 | .556 |
| Mike Stanton* |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 10 | .270 |
| Tim Stauffer | MAD | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 20 | 10.0 | 2 | 2 | 1.000 |
| Mitch Stetter* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Brian Stokes |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 10 | .500 |
| Ricky Stone |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Huston Street | GEO | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Eric Stults* |   | mr | 27 | 5 | 0 | .000 | 0 | 1 | .200 | 17 | 3.4 | 9 | 2 | .222 |
| Jeff Suppan |   | sp | 32 | 34 | 1 | .029 | 0 | 15 | .441 | 172 | 5.1 | 19 | 4 | .211 |
| Jon Switzer* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 |
| Brian Tallet* | EDG | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 9 | .474 |
| Taylor Tankersley* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 8 | .267 |
| Jack Taschner* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 12 | .429 |
| Jordan Tata |   | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 16 | 5.3 | 1 | 1 | 1.000 |
| Ty Taubenheim |   | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 2 | 2 | 1.000 |
| Julian Tavarez |   | sp | 34 | 23 | 0 | .000 | 0 | 7 | .304 | 111 | 4.8 | 22 | 3 | .136 |
| Robinson Tejeda |   | sp | 25 | 19 | 0 | .000 | 0 | 4 | .211 | 91 | 4.8 | 18 | 6 | .333 |
| Joe Thatcher* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 |
| Brad Thompson |   | mr | 25 | 17 | 0 | .000 | 0 | 8 | .471 | 95 | 5.6 | 17 | 7 | .412 |
| Mike Thompson |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Rich Thompson |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| John Thomson |   | sp | 33 | 2 | 0 | .000 | 0 | 1 | .500 | 6 | 3.0 | 2 | 0 | .000 |
| Matt Thornton* | CRH | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 11 | .333 |
| Erick Threets* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Mike Timlin | OTR | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 |
| Brett Tomko |   | mr | 34 | 19 | 0 | .000 | 0 | 8 | .421 | 76 | 4.0 | 23 | 9 | .391 |
| Salomon Torres |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Josh Towers |   | sp | 30 | 15 | 0 | .000 | 0 | 4 | .267 | 53 | 3.5 | 18 | 9 | .500 |
| Billy Traber* |   | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 1 | 0.5 | 10 | 2 | .200 |
| Steve Trachsel |   | sp | 36 | 29 | 1 | .034 | 0 | 13 | .448 | 134 | 4.6 | 23 | 5 | .217 |
| Chin-hui Tsao |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Derrick Turnbow | MAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 14 | .500 |
| Lino Urdaneta |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Jose Valverde | WIZ | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| John Van Benschoten |   | sp | 27 | 9 | 0 | .000 | 0 | 1 | .111 | 21 | 2.3 | 8 | 4 | .500 |
| Rick VandenHurk |   | sp | 22 | 17 | 0 | .000 | 0 | 2 | .118 | 82 | 4.8 | 16 | 4 | .250 |
| Claudio Vargas |   | sp | 29 | 23 | 0 | .000 | 0 | 9 | .391 | 133 | 5.8 | 10 | 1 | .100 |
| Jason Vargas* |   | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 3 | 3 | 1.000 |
| Virgil Vasquez |   | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 3 | 0 | .000 |
| Javier Vazquez | Pal | sp | 30 | 32 | 2 | .063 | 0 | 20 | .625 | 151 | 4.7 | 13 | 4 | .308 |
| Jose Veras |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Justin Verlander | COP | sp | 24 | 32 | 1 | .031 | 1 | 21 | .656 | 196 | 6.1 | 17 | 7 | .412 |
| Jamie Vermilyea |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Carlos Villanueva | TON | mr | 23 | 6 | 0 | .000 | 0 | 4 | .667 | 20 | 3.3 | 25 | 8 | .320 |
| Oscar Villarreal |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Ron Villone* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 |
| Luis Vizcaino | LON | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 |
| Edinson Volquez |   | sp | 23 | 6 | 0 | .000 | 0 | 2 | .333 | 30 | 5.0 | 2 | 0 | .000 |
| Billy Wagner* | BT | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Ryan Wagner |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Adam Wainwright | MAD | sp | 25 | 32 | 1 | .031 | 0 | 21 | .656 | 154 | 4.8 | 13 | 8 | .615 |
| Tim Wakefield | OTR | sp | 40 | 31 | 0 | .000 | 0 | 15 | .484 | 160 | 5.2 | 20 | 12 | .600 |
| Jamie Walker* | OTR | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 9 | .231 |
| Tyler Walker |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chien-Ming Wang | MID | sp | 27 | 30 | 1 | .033 | 0 | 20 | .667 | 193 | 6.4 | 14 | 6 | .429 |
| John Wasdin |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Jarrod Washburn* |   | sp | 32 | 32 | 1 | .031 | 1 | 17 | .531 | 144 | 4.5 | 30 | 10 | .333 |
| Ehren Wassermann |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 |
| David Weathers | TON | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Jeff Weaver |   | sp | 30 | 27 | 3 | .111 | 2 | 9 | .333 | 131 | 4.9 | 18 | 7 | .389 |
| Jered Weaver | OTR | sp | 24 | 28 | 0 | .000 | 0 | 16 | .571 | 141 | 5.0 | 11 | 3 | .273 |
| Brandon Webb | TON | sp | 28 | 34 | 4 | .118 | 3 | 22 | .647 | 136 | 4.0 | 8 | 2 | .250 |
| Todd Wellemeyer |   | mr | 28 | 11 | 0 | .000 | 0 | 2 | .182 | 70 | 6.4 | 12 | 3 | .250 |
| David Wells* |   | sp | 44 | 29 | 0 | .000 | 0 | 12 | .414 | 124 | 4.3 | 17 | 3 | .176 |
| Kip Wells |   | sp | 30 | 26 | 0 | .000 | 0 | 9 | .346 | 91 | 3.5 | 19 | 8 | .421 |
| Jake Westbrook | MID | sp | 29 | 25 | 0 | .000 | 0 | 15 | .600 | 96 | 3.8 | 10 | 4 | .400 |
| Dan Wheeler | Pal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 |
| Bill White* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 |
| Rick White |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 9 | .750 |
| Sean White |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Bob Wickman |   | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Dave Williams* |   | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 2 | 0 | .000 |
| Jerome Williams |   | sp | 25 | 6 | 0 | .000 | 0 | 1 | .167 | 18 | 3.0 | 4 | 2 | .500 |
| Todd Williams |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 |
| Woody Williams |   | sp | 40 | 31 | 0 | .000 | 0 | 15 | .484 | 126 | 4.1 | 12 | 6 | .500 |
| Scott Williamson |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Dontrelle Willis* |   | sp | 25 | 35 | 0 | .000 | 0 | 16 | .457 | 186 | 5.3 | 18 | 5 | .278 |
| Brian Wilson |   | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| C.J. Wilson* | ROK | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 |
| Matt Wise |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 8 | .500 |
| Jay Witasick |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 |
| Randy Wolf* | CCL | sp | 30 | 18 | 0 | .000 | 0 | 8 | .444 | 88 | 4.9 | 9 | 3 | .333 |
| Ross Wolf |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Brian Wolfe | OTR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Kerry Wood | MUL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Mike Wood |   | mr | 27 | 4 | 0 | .000 | 0 | 1 | .250 | 16 | 4.0 | 9 | 3 | .333 |
| Jake Woods* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chase Wright* |   | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 16 | 8.0 | 0 | 0 | .000 |
| Jamey Wright |   | mr | 32 | 9 | 0 | .000 | 0 | 2 | .222 | 46 | 5.1 | 13 | 3 | .231 |
| Jaret Wright |   | sp | 31 | 3 | 0 | .000 | 0 | 0 | .000 | 4 | 1.3 | 4 | 4 | 1.000 |
| Michael Wuertz | BT | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 5 | .192 |
| Tyler Yates |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 20 | .741 |
| Shane Youman* |   | sp | 27 | 8 | 0 | .000 | 0 | 3 | .375 | 30 | 3.8 | 4 | 4 | 1.000 |
| Chris Young | COP | sp | 28 | 30 | 0 | .000 | 0 | 18 | .600 | 111 | 3.7 | 19 | 5 | .263 |
| Mike Zagurski* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 |
| Carlos Zambrano | CCL | sp | 26 | 34 | 1 | .029 | 0 | 18 | .529 | 157 | 4.6 | 27 | 11 | .407 |
| Victor Zambrano |   | mr | 31 | 4 | 0 | .000 | 0 | 0 | .000 | 19 | 4.8 | 11 | 5 | .455 |
| Mauro Zarate |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Barry Zito* | EDG | sp | 29 | 33 | 0 | .000 | 0 | 18 | .545 | 137 | 4.2 | 16 | 8 | .500 |
| Joel Zumaya |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF |
| David Aardsma | BT | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 4 | 16 | 6 | .375 | 25 | 25 | 7 |
| Winston Abreu |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 5 | 23 | 11 | .478 | 26 | 26 | 3 |
| Jeremy Accardo | CRH | cl | 25 | 35 | 30 | .857 | 5 | .143 | 2 | 23 | 2 | .087 | 64 | 64 | 48 |
| Manny Acosta |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 4 | 10 | 4 | .400 | 21 | 21 | 5 |
| Jon Adkins |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Jeremy Affeldt* | CRH | mr | 28 | 5 | 0 | .000 | 5 | 1.000 | 9 | 49 | 14 | .286 | 75 | 75 | 11 |
| Jonathan Albaladejo |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 3 | 13 | 6 | .462 | 14 | 14 | 1 |
| Matt Albers |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 13 | 2 |
| Antonio Alfonseca |   | mr | 35 | 14 | 8 | .571 | 6 | .429 | 15 | 32 | 10 | .313 | 61 | 61 | 22 |
| Greg Aquino |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 2 | 9 | 8 | .889 | 15 | 15 | 8 |
| Alberto Arias |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 7 | 5 | .714 | 6 | 6 | 0 |
| Tony Armas |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 4 | .500 | 31 | 16 | 6 |
| Bronson Arroyo | BT | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jose Ascanio |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 13 | 13 | 6 |
| Scott Atchison |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 6 | 16 | 6 | .375 | 22 | 22 | 4 |
| Luis Ayala |   | mr | 29 | 2 | 1 | .500 | 1 | .500 | 6 | 22 | 9 | .409 | 44 | 44 | 11 |
| Brandon Backe |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Mike Bacsik* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 1 | .143 | 29 | 9 | 0 |
| Cha Seung Baek | EDG | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 14 | 2 | 1 |
| Danys Baez |   | mr | 29 | 5 | 3 | .600 | 2 | .400 | 14 | 19 | 8 | .421 | 53 | 53 | 25 |
| Homer Bailey | CCL | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Scott Baker | BON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 24 | 1 | 0 |
| John Bale* | BON | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 5 | 12 | 7 | .583 | 26 | 26 | 5 |
| Grant Balfour |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 5 | .455 | 25 | 25 | 8 |
| Josh Banks |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 1 |
| Brian Bannister | EDG | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Daniel Barone |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 2 | .222 | 16 | 10 | 4 |
| Kevin Barry |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Miguel Batista |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 1 | 0 |
| Denny Bautista |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 3 | 2 | .667 | 9 | 8 | 2 |
| Jonah Bayliss |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 4 | 27 | 5 | .185 | 39 | 39 | 11 |
| Yorman Bazardo |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 11 | 9 | 6 |
| Colter Bean |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 3 | 1.000 | 3 | 3 | 0 |
| Josh Beckett | Pal | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Erik Bedard* | GEO | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Joe Beimel* | WIZ | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 16 | 57 | 10 | .175 | 83 | 83 | 10 |
| Matt Belisle | CCL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Heath Bell | MUL | mr | 29 | 6 | 2 | .333 | 4 | .667 | 34 | 34 | 6 | .176 | 81 | 81 | 16 |
| Rob Bell |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 2 | 27 | 10 | .370 | 30 | 30 | 8 |
| Armando Benitez |   | mr | 34 | 16 | 9 | .563 | 7 | .438 | 11 | 8 | 4 | .500 | 55 | 55 | 24 |
| Jeff Bennett |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 0 |
| Joaquin Benoit | OTR | mr | 29 | 13 | 6 | .462 | 7 | .538 | 19 | 20 | 6 | .300 | 70 | 70 | 22 |
| Jason Bergmann |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| Rafael Betancourt | GEO | mr | 32 | 6 | 3 | .500 | 3 | .500 | 31 | 33 | 3 | .091 | 68 | 68 | 15 |
| Chad Billingsley | TON | mr | 22 | 1 | 0 | .000 | 1 | 1.000 | 3 | 6 | 4 | .667 | 43 | 23 | 6 |
| Kurt Birkins* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 22 | 9 | .409 | 19 | 17 | 7 |
| Joe Bisenius |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 2 | 2 | 0 |
| Nick Blackburn |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 1 | 0 | 0 | .000 | 6 | 6 | 3 |
| Travis Blackley* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Joe Blanton | BON | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jerry Blevins* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 6 | 6 | 1 |
| Jeremy Bonderman |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Boof Bonser |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 0 |
| Chris Booker |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 1 | .333 | 3 | 3 | 1 |
| Chris Bootcheck |   | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 4 | 31 | 7 | .226 | 51 | 51 | 17 |
| Dave Borkowski |   | mr | 30 | 4 | 1 | .250 | 3 | .750 | 9 | 39 | 12 | .308 | 64 | 64 | 18 |
| Joe Borowski | EDG | cl | 36 | 53 | 45 | .849 | 8 | .151 | 0 | 8 | 1 | .125 | 69 | 69 | 58 |
| Micah Bowie* |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 2 | 21 | 6 | .286 | 30 | 22 | 2 |
| Blaine Boyer |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 5 | 5 | 2 |
| Dallas Braden* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 20 | 6 | 1 |
| Chad Bradford | MID | mr | 32 | 7 | 2 | .286 | 5 | .714 | 19 | 58 | 21 | .362 | 78 | 78 | 14 |
| Ryan Braun |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 21 | 7 | .333 | 26 | 26 | 10 |
| Bill Bray* |   | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 11 | 2 | .182 | 19 | 19 | 5 |
| Yhency Brazoban |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 4 | 4 | 1 |
| Chris Britton |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 1 | .091 | 11 | 11 | 4 |
| Lance Broadway |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 4 | 3 | 1 |
| Doug Brocail | CCL | mr | 40 | 0 | 0 | .000 | 0 | .000 | 11 | 28 | 9 | .321 | 67 | 67 | 16 |
| Jim Brower |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 3 | 3 | 0 |
| Andrew Brown | EDG | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 16 | 2 | .125 | 33 | 33 | 5 |
| Jonathan Broxton | CCL | mr | 23 | 8 | 2 | .250 | 6 | .750 | 32 | 23 | 7 | .304 | 83 | 83 | 18 |
| Brian Bruney |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 7 | 40 | 14 | .350 | 58 | 58 | 16 |
| Clay Buchholz |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 0 |
| Taylor Buchholz | TON | mr | 25 | 0 | 0 | .000 | 0 | .000 | 5 | 22 | 9 | .409 | 41 | 33 | 6 |
| Billy Buckner |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 7 | 2 | 1 |
| Mark Buehrle* | GEO | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Ryan Bukvich |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 5 | 39 | 14 | .359 | 45 | 45 | 7 |
| Jason Bulger |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 6 | 4 |
| Bryan Bullington |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 2 | 0 |
| Ambiorix Burgos |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 2 | .286 | 17 | 17 | 5 |
| A.J. Burnett | TON | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Brian Burres* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 3 | .214 | 37 | 20 | 9 |
| Jared Burton | MAD | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 11 | 18 | 4 | .222 | 47 | 47 | 12 |
| Dave Bush | OTR | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 2 | 2 |
| Paul Byrd |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Tim Byrdak* | EDG | mr | 33 | 3 | 1 | .333 | 2 | .667 | 8 | 34 | 12 | .353 | 39 | 39 | 3 |
| Daniel Cabrera |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Fernando Cabrera |   | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 15 | 9 | .600 | 33 | 33 | 13 |
| Matt Cain | LON | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Kiko Calero |   | mr | 32 | 4 | 1 | .250 | 3 | .750 | 10 | 28 | 9 | .321 | 46 | 46 | 6 |
| Carmen Cali* |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 2 | 13 | 4 | .308 | 24 | 24 | 7 |
| Kevin Cameron | LON | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 27 | 4 | .148 | 48 | 48 | 20 |
| Shawn Camp |   | mr | 31 | 2 | 0 | .000 | 2 | 1.000 | 11 | 54 | 22 | .407 | 50 | 50 | 8 |
| Jorge Campillo |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 5 | 5 | 2 |
| Jose Capellan |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 3 | .300 | 17 | 17 | 9 |
| Matt Capps | MUL | mr | 23 | 21 | 18 | .857 | 3 | .143 | 15 | 11 | 5 | .455 | 76 | 76 | 47 |
| Chris Capuano* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 4 | 0 |
| Buddy Carlyle |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 2 | 1 |
| Fausto Carmona | GEO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Chris Carpenter | CRH | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Hector Carrasco |   | mr | 37 | 0 | 0 | .000 | 0 | .000 | 2 | 18 | 9 | .500 | 29 | 28 | 9 |
| Marcos Carvajal |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 3 |
| Santiago Casilla | OTR | mr | 26 | 5 | 2 | .400 | 3 | .600 | 12 | 31 | 5 | .161 | 46 | 46 | 10 |
| Jack Cassel |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 2 | 0 |
| Fabio Castro* |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 10 | 9 | 4 |
| Troy Cate* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 3 | 8 | 2 | .250 | 14 | 14 | 4 |
| Andy Cavazos |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 2 | .167 | 17 | 17 | 5 |
| Gustavo Chacin* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Shawn Chacon |   | mr | 29 | 8 | 1 | .125 | 7 | .875 | 12 | 20 | 13 | .650 | 64 | 60 | 11 |
| Joba Chamberlain |   | mr | 21 | 1 | 1 | 1.000 | 0 | .000 | 9 | 2 | 0 | .000 | 19 | 19 | 3 |
| Bruce Chen* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 5 | 5 | 3 |
| Rocky Cherry |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 16 | 6 | .375 | 22 | 22 | 2 |
| Matt Chico* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Randy Choate* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 |
| Vinnie Chulk |   | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 9 | 39 | 15 | .385 | 57 | 57 | 15 |
| Darren Clarke |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 0 |
| Roger Clemens | ROK | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 1 | 0 |
| Tyler Clippard |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Todd Coffey |   | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 7 | 44 | 19 | .432 | 58 | 58 | 8 |
| Willie Collazo* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 6 | 6 | 1 |
| Jesus Colome |   | mr | 29 | 4 | 1 | .250 | 3 | .750 | 12 | 23 | 8 | .348 | 61 | 61 | 16 |
| Bartolo Colon |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 19 | 1 | 0 |
| Steve Colyer* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 2 | .500 | 7 | 7 | 1 |
| Clay Condrey |   | mr | 31 | 2 | 2 | 1.000 | 0 | .000 | 3 | 29 | 12 | .414 | 39 | 39 | 14 |
| Jose Contreras |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 2 | 2 |
| Aaron Cook | MAD | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Tim Corcoran |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 9 | .750 | 9 | 9 | 3 |
| Chad Cordero |   | cl | 25 | 46 | 37 | .804 | 9 | .196 | 1 | 5 | 2 | .400 | 76 | 76 | 59 |
| Francisco Cordero | CRH | cl | 32 | 51 | 44 | .863 | 7 | .137 | 0 | 17 | 4 | .235 | 66 | 66 | 58 |
| Bryan Corey |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 9 | 9 | 2 |
| Lance Cormier |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 1 | 1 |
| Rheal Cormier* |   | mr | 40 | 0 | 0 | .000 | 0 | .000 | 3 | 6 | 2 | .333 | 6 | 6 | 1 |
| Manny Corpas | MUL | mr | 24 | 22 | 19 | .864 | 3 | .136 | 16 | 18 | 7 | .389 | 78 | 78 | 46 |
| Kevin Correia | MUL | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 12 | 17 | 7 | .412 | 59 | 51 | 9 |
| Neal Cotts* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 14 | 5 | .357 | 16 | 16 | 4 |
| Jon Coutlangus* |   | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 11 | 53 | 14 | .264 | 64 | 64 | 9 |
| Jesse Crain |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 6 | 7 | 1 | .143 | 18 | 18 | 5 |
| Juan Cruz | TON | mr | 28 | 0 | 0 | .000 | 0 | .000 | 4 | 27 | 7 | .259 | 53 | 53 | 15 |
| John Danks* | EDG | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Dave Davidson* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Kyle Davies |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Doug Davis* |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jason Davis |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 6 | 1 | .167 | 24 | 24 | 9 |
| Kane Davis |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 3 | 4 | 2 | .500 | 11 | 11 | 1 |
| Dewon Day |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 4 | .364 | 13 | 13 | 6 |
| Jordan De Jong |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 6 | 4 |
| Eulogio De La Cruz |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 6 | 6 | 4 |
| Jorge De La Rosa* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 3 | 1 |
| Manny Delcarmen | GEO | mr | 25 | 2 | 1 | .500 | 1 | .500 | 11 | 26 | 5 | .192 | 44 | 44 | 5 |
| Ryan Dempster | CRH | cl | 30 | 31 | 28 | .903 | 3 | .097 | 0 | 6 | 0 | .000 | 66 | 66 | 58 |
| Julio DePaula |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 16 | 16 | 7 |
| Matt DeSalvo |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 0 |
| Elmer Dessens |   | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 17 | 12 | 7 |
| Ross Detwiler* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Joey Devine |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 1 | .167 | 10 | 10 | 5 |
| Lenny DiNardo* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 2 | .182 | 35 | 15 | 9 |
| Scott Dohmann |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 5 | 19 | 6 | .316 | 31 | 31 | 8 |
| Brendan Donnelly |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 8 | 21 | 5 | .238 | 27 | 27 | 4 |
| Octavio Dotel |   | cl | 33 | 15 | 11 | .733 | 4 | .267 | 1 | 6 | 0 | .000 | 33 | 33 | 25 |
| Dennis Dove |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Scott Downs* | EDG | mr | 31 | 4 | 1 | .250 | 3 | .750 | 25 | 50 | 13 | .260 | 81 | 81 | 13 |
| Cory Doyne |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 5 | 5 | 3 |
| Travis Driskill |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Justin Duchscherer | COP | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 5 | 7 | 2 | .286 | 17 | 17 | 2 |
| Brandon Duckworth |   | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 7 | 10 | 3 | .300 | 26 | 23 | 6 |
| Zach Duke* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 1 | 0 |
| Phil Dumatrait* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Chad Durbin |   | sp | 29 | 2 | 1 | .500 | 1 | .500 | 4 | 13 | 5 | .385 | 36 | 17 | 7 |
| J.D. Durbin |   | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 19 | 9 | 4 |
| Adam Eaton |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Scott Elarton |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Alan Embree* | BON | cl | 37 | 21 | 17 | .810 | 4 | .190 | 16 | 31 | 7 | .226 | 68 | 68 | 36 |
| John Ennis |   | cl | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 2 | 1 |
| Kelvim Escobar | BON | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Dana Eveland* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 5 | 4 | 0 |
| Scott Eyre* |   | mr | 35 | 4 | 0 | .000 | 4 | 1.000 | 6 | 27 | 9 | .333 | 55 | 55 | 17 |
| Willie Eyre |   | mr | 28 | 2 | 1 | .500 | 1 | .500 | 2 | 23 | 2 | .087 | 33 | 31 | 10 |
| Brian Falkenborg |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 4 | .571 | 16 | 16 | 2 |
| Kyle Farnsworth |   | mr | 31 | 3 | 0 | .000 | 3 | 1.000 | 15 | 0 | 0 | .000 | 64 | 64 | 11 |
| Ryan Feierabend* |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 13 | 4 | 0 |
| Scott Feldman | MID | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 22 | 8 | .364 | 29 | 29 | 10 |
| Pedro Feliciano* | MAD | mr | 30 | 4 | 2 | .500 | 2 | .500 | 18 | 60 | 12 | .200 | 78 | 78 | 12 |
| Nate Field |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Randy Flores* |   | mr | 31 | 2 | 1 | .500 | 1 | .500 | 15 | 34 | 19 | .559 | 70 | 70 | 11 |
| Ron Flores* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 7 | 3 | .429 | 17 | 17 | 4 |
| Gavin Floyd | TON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 16 | 6 | 4 |
| Josh Fogg |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 1 | 0 |
| Casey Fossum* |   | mr | 29 | 4 | 0 | .000 | 4 | 1.000 | 2 | 30 | 14 | .467 | 40 | 30 | 7 |
| Jeff Francis* | MAD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Frank Francisco | EDG | mr | 27 | 0 | 0 | .000 | 0 | .000 | 21 | 44 | 3 | .068 | 59 | 59 | 16 |
| Ryan Franklin | LON | mr | 34 | 6 | 1 | .167 | 5 | .833 | 25 | 24 | 6 | .250 | 69 | 69 | 8 |
| Jason Frasor | MID | mr | 29 | 7 | 3 | .429 | 4 | .571 | 4 | 28 | 10 | .357 | 51 | 51 | 18 |
| Brian Fuentes* | CCL | cl | 31 | 27 | 20 | .741 | 7 | .259 | 8 | 6 | 0 | .000 | 64 | 64 | 38 |
| Aaron Fultz* | MAD | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 11 | 45 | 14 | .311 | 49 | 49 | 10 |
| Kason Gabbard* | CRH | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Eric Gagne | GEO | cl | 31 | 20 | 16 | .800 | 4 | .200 | 4 | 7 | 2 | .286 | 54 | 54 | 41 |
| Armando Galarraga |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 2 |
| Sean Gallagher |   | mr | 21 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 1 | .167 | 8 | 8 | 3 |
| Yovani Gallardo | LON | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 20 | 3 | 1 |
| Anderson Garcia |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Freddy Garcia |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 |
| Harvey Garcia |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 8 | 8 | 0 |
| Lee Gardner | MAD | mr | 32 | 2 | 2 | 1.000 | 0 | .000 | 9 | 37 | 10 | .270 | 62 | 62 | 20 |
| Jon Garland | COP | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Matt Garza | GEO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 1 |
| Chad Gaudin |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Geoff Geary |   | mr | 30 | 4 | 0 | .000 | 4 | 1.000 | 11 | 60 | 14 | .233 | 57 | 57 | 10 |
| Justin Germano | CCL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 3 | 3 |
| Dan Giese |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 8 | 8 | 3 |
| Tom Glavine* | WIZ | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Gary Glover |   | mr | 30 | 4 | 2 | .500 | 2 | .500 | 11 | 37 | 9 | .243 | 67 | 67 | 18 |
| Jimmy Gobble* |   | mr | 25 | 3 | 1 | .333 | 2 | .667 | 17 | 61 | 19 | .311 | 74 | 74 | 12 |
| Edgar Gonzalez |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 3 | .273 | 32 | 20 | 5 |
| Enrique Gonzalez |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Mike Gonzalez* |   | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 5 | 2 | 2 | 1.000 | 18 | 18 | 5 |
| Tom Gordon |   | mr | 39 | 11 | 6 | .545 | 5 | .455 | 14 | 6 | 1 | .167 | 44 | 44 | 11 |
| Tom Gorzelanny* | LON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Mike Gosling* |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 10 | 5 | .500 | 23 | 23 | 7 |
| John Grabow* |   | mr | 28 | 2 | 1 | .500 | 1 | .500 | 9 | 47 | 17 | .362 | 63 | 63 | 14 |
| Sean Green |   | mr | 28 | 3 | 0 | .000 | 3 | 1.000 | 13 | 68 | 21 | .309 | 64 | 64 | 10 |
| Kevin Gregg | BT | cl | 29 | 36 | 32 | .889 | 4 | .111 | 7 | 20 | 3 | .150 | 74 | 74 | 55 |
| Zack Greinke | COP | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 14 | 34 | 7 | .206 | 52 | 38 | 7 |
| Jason Grilli | COP | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 13 | 53 | 16 | .302 | 57 | 57 | 13 |
| Lee Gronkiewicz |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Eddie Guardado* |   | mr | 36 | 2 | 0 | .000 | 2 | 1.000 | 1 | 4 | 3 | .750 | 15 | 15 | 2 |
| Matt Guerrier | MID | mr | 28 | 4 | 1 | .250 | 3 | .750 | 14 | 45 | 14 | .311 | 73 | 73 | 16 |
| Jeremy Guthrie | MID | sp | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 7 | 1.000 | 32 | 6 | 3 |
| Juan Gutierrez |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 4 | 1 |
| Angel Guzman |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 5 | 3 | .600 | 12 | 9 | 3 |
| Marc Gwyn |   | cl | 29 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 3 | 2 |
| Charlie Haeger |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 8 | 8 | 5 |
| Roy Halladay | ROK | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Cole Hamels* | BT | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Jason Hammel | EDG | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 4 | .444 | 24 | 10 | 2 |
| Justin Hampson* | CCL | mr | 27 | 0 | 0 | .000 | 0 | .000 | 5 | 17 | 5 | .294 | 39 | 39 | 12 |
| Josh Hancock |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 8 | 4 |
| Joel Hanrahan | CCL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 12 | 1 | 0 |
| Devern Hansack |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 0 |
| J.A. Happ* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Aaron Harang | GEO | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Rich Harden | COP | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 3 | 2 |
| Dan Haren | LON | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Tim Harikkala |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Kevin Hart |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 8 | 8 | 2 |
| LaTroy Hawkins | BT | mr | 34 | 5 | 0 | .000 | 5 | 1.000 | 18 | 17 | 4 | .235 | 62 | 62 | 10 |
| Aaron Heilman | WIZ | mr | 28 | 6 | 1 | .167 | 5 | .833 | 22 | 29 | 8 | .276 | 81 | 81 | 28 |
| Mark Hendrickson* | MUL | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 2 | 15 | 4 | .267 | 39 | 24 | 4 |
| Sean Henn* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 5 | .385 | 29 | 28 | 8 |
| Brad Hennessey |   | cl | 27 | 24 | 19 | .792 | 5 | .208 | 13 | 32 | 14 | .438 | 69 | 69 | 34 |
| Clay Hensley |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 13 | 4 | 1 |
| Matt Herges | LON | mr | 37 | 2 | 0 | .000 | 2 | 1.000 | 5 | 16 | 4 | .250 | 35 | 35 | 9 |
| Felix Hernandez | ROK | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Livan Hernandez |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Orlando Hernandez | Pal | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 3 | 0 |
| Roberto Hernandez |   | mr | 42 | 1 | 0 | .000 | 1 | 1.000 | 5 | 23 | 8 | .348 | 50 | 50 | 20 |
| Yoel Hernandez |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 12 | 7 | .583 | 14 | 14 | 7 |
| Rich Hill* | BT | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Shawn Hill | WIZ | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 |
| Jason Hirsh | WIZ | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 |
| Luke Hochevar |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 3 | 1 |
| Jim Hoey |   | mr | 24 | 3 | 0 | .000 | 3 | 1.000 | 4 | 12 | 1 | .083 | 23 | 23 | 1 |
| Trevor Hoffman | Pal | cl | 39 | 49 | 42 | .857 | 7 | .143 | 0 | 9 | 3 | .333 | 61 | 61 | 50 |
| D.J. Houlton |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 1 | .250 | 18 | 18 | 8 |
| J.P. Howell* | MID | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Bob Howry | COP | mr | 33 | 12 | 8 | .667 | 4 | .333 | 22 | 25 | 6 | .240 | 78 | 78 | 32 |
| Jon Huber |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 10 | 0 | .000 | 9 | 9 | 3 |
| Luke Hudson |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Tim Hudson | GEO | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Phil Hughes | COP | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Eric Hull |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 5 | 5 | 3 |
| Philip Humber |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 2 |
| Kei Igawa* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 14 | 2 | 0 |
| Jason Isringhausen | Pal | cl | 34 | 34 | 32 | .941 | 2 | .059 | 0 | 13 | 2 | .154 | 63 | 63 | 54 |
| Edwin Jackson |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 32 | 1 | 0 |
| Chuck James* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Casey Janssen | OTR | mr | 25 | 11 | 6 | .545 | 5 | .455 | 24 | 49 | 14 | .286 | 70 | 70 | 21 |
| Bobby Jenks | OTR | cl | 26 | 46 | 40 | .870 | 6 | .130 | 0 | 18 | 6 | .333 | 66 | 66 | 62 |
| Jason Jennings |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 1 | 0 |
| Kelvin Jimenez |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 28 | 9 | .321 | 34 | 34 | 15 |
| Ubaldo Jimenez | TON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Jim Johnson |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Josh Johnson | LON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Randy Johnson* | ROK | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Tyler Johnson* |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 6 | 35 | 12 | .343 | 55 | 55 | 6 |
| Greg Jones |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 7 | .875 | 9 | 9 | 8 |
| Todd Jones | MUL | cl | 39 | 44 | 38 | .864 | 6 | .136 | 0 | 7 | 2 | .286 | 63 | 63 | 54 |
| Jorge Julio |   | mr | 28 | 8 | 0 | .000 | 8 | 1.000 | 17 | 39 | 13 | .333 | 68 | 68 | 14 |
| Jair Jurrjens |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Jeff Karstens |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 7 | 4 | 2 |
| Scott Kazmir* | GEO | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Randy Keisler* |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 |
| Kyle Kendrick |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Ian Kennedy |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Joe Kennedy* |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 3 | 13 | 9 | .692 | 39 | 23 | 6 |
| Logan Kensing |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 9 | 9 | 0 |
| Bobby Keppel |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 1 |
| Byung-Hyun Kim |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 28 | 6 | 4 |
| Ray King* |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 11 | 47 | 10 | .213 | 67 | 67 | 10 |
| Steve Kline* |   | mr | 34 | 4 | 2 | .500 | 2 | .500 | 9 | 32 | 6 | .188 | 68 | 68 | 19 |
| Dan Kolb |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Shane Komine |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 2 | 2 | 1 |
| Mike Koplove |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 5 | 5 | 4 |
| John Koronka* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Hong-Chih Kuo* | Pal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 1 |
| Masumi Kuwata |   | mr | 39 | 1 | 0 | .000 | 1 | 1.000 | 3 | 8 | 3 | .375 | 19 | 19 | 3 |
| John Lackey | COP | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Aaron Laffey* | EDG | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| John Lannan* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Juan Lara* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 1 |
| Brian Lawrence |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Brandon League |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 10 | 5 | .500 | 14 | 14 | 2 |
| Wilfredo Ledezma* |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 17 | 5 | .294 | 44 | 43 | 13 |
| Cliff Lee* | MID | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 20 | 4 | 1 |
| Jon Leicester |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 10 | 5 | 1 |
| Anthony Lerew |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Jon Lester* | EDG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 1 | 0 |
| Colby Lewis |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 3 | 21 | 11 | .524 | 26 | 25 | 8 |
| Jensen Lewis |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 5 | 19 | 4 | .211 | 26 | 26 | 5 |
| Brad Lidge | Pal | cl | 30 | 27 | 19 | .704 | 8 | .296 | 7 | 12 | 3 | .250 | 66 | 66 | 34 |
| Jon Lieber | MUL | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 14 | 2 | 1 |
| Ted Lilly* | OTR | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Tim Lincecum | WIZ | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Matt Lindstrom | MUL | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 22 | 29 | 10 | .345 | 71 | 71 | 11 |
| Scott Linebrink |   | mr | 30 | 8 | 1 | .125 | 7 | .875 | 21 | 16 | 4 | .250 | 71 | 71 | 11 |
| Jesse Litsch | EDG | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Wes Littleton |   | mr | 24 | 3 | 2 | .667 | 1 | .333 | 3 | 26 | 11 | .423 | 35 | 35 | 11 |
| Bobby Livingston* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Radhames Liz |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 9 | 5 | 5 |
| Esteban Loaiza |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Kameron Loe |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 5 | 0 |
| Adam Loewen* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Boone Logan* |   | mr | 22 | 3 | 0 | .000 | 3 | 1.000 | 11 | 78 | 22 | .282 | 68 | 68 | 13 |
| Kyle Lohse | COP | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 2 | 0 |
| Braden Looper | MAD | sp | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 31 | 1 | 0 |
| Aquilino Lopez |   | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 1 | 4 | 0 | .000 | 10 | 10 | 6 |
| Javier Lopez* | OTR | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 13 | 49 | 15 | .306 | 61 | 61 | 11 |
| Rodrigo Lopez | CCL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Derek Lowe | BON | sp | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 33 | 1 | 0 |
| Mark Lowe |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 2 | 0 | .000 | 4 | 4 | 1 |
| Noah Lowry* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Ruddy Lugo |   | mr | 27 | 4 | 0 | .000 | 4 | 1.000 | 1 | 38 | 19 | .500 | 38 | 38 | 14 |
| Brandon Lyon | Pal | mr | 27 | 5 | 2 | .400 | 3 | .600 | 35 | 21 | 6 | .286 | 73 | 73 | 20 |
| Mike MacDougal |   | mr | 30 | 3 | 0 | .000 | 3 | 1.000 | 19 | 49 | 17 | .347 | 54 | 54 | 8 |
| Greg Maddux | Pal | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Ryan Madson | CCL | mr | 26 | 2 | 1 | .500 | 1 | .500 | 7 | 8 | 5 | .625 | 38 | 38 | 9 |
| Ron Mahay* |   | mr | 36 | 3 | 1 | .333 | 2 | .667 | 10 | 37 | 13 | .351 | 58 | 58 | 8 |
| Paul Maholm* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| John Maine | BT | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Gary Majewski |   | mr | 27 | 3 | 0 | .000 | 3 | 1.000 | 6 | 22 | 7 | .318 | 32 | 32 | 3 |
| Shaun Marcum | COP | sp | 25 | 2 | 1 | .500 | 1 | .500 | 2 | 7 | 4 | .571 | 38 | 13 | 6 |
| Carlos Marmol | WIZ | mr | 24 | 2 | 1 | .500 | 1 | .500 | 17 | 41 | 5 | .122 | 59 | 59 | 6 |
| Mike Maroth* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 7 | 2 |
| Jason Marquis | MUL | sp | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 34 | 1 | 0 |
| Jay Marshall* |   | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 9 | 36 | 6 | .167 | 51 | 51 | 15 |
| Sean Marshall* | LON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 2 | 0 |
| Damaso Marte* | WIZ | mr | 32 | 0 | 0 | .000 | 0 | .000 | 15 | 45 | 11 | .244 | 65 | 65 | 11 |
| Tom Martin* |   | mr | 37 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 3 | .250 | 26 | 26 | 7 |
| Carlos Martinez |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 |
| Pedro Martinez |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Nick Masset |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 18 | 6 | .333 | 27 | 26 | 4 |
| Tom Mastny |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 7 | 27 | 11 | .407 | 51 | 51 | 18 |
| Julio Mateo |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 0 | 5 | 5 | 1.000 | 9 | 9 | 1 |
| Daisuke Matsuzaka | OTR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Marcus McBeth |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 8 | 3 | .375 | 23 | 23 | 7 |
| Macay McBride* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 4 | 30 | 11 | .367 | 38 | 38 | 5 |
| Brandon McCarthy | EDG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 1 | 0 |
| Zach McClellan |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 2 | .667 | 12 | 12 | 1 |
| Seth McClung |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 2 | .200 | 14 | 14 | 1 |
| Dustin McGowan | OTR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Marty McLeary |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 3 | .375 | 4 | 4 | 0 |
| Mark McLemore* |   | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 1 | 10 | 5 | .500 | 29 | 29 | 9 |
| Gil Meche | CRH | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Brandon Medders |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 2 | 11 | 4 | .364 | 30 | 30 | 7 |
| Jonathan Meloan |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 5 | 3 |
| Luis Mendoza |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 6 | 3 | 2 |
| Cla Meredith |   | mr | 24 | 6 | 0 | .000 | 6 | 1.000 | 10 | 52 | 21 | .404 | 80 | 80 | 18 |
| Jose Mesa |   | mr | 41 | 1 | 1 | 1.000 | 0 | .000 | 7 | 31 | 10 | .323 | 56 | 56 | 21 |
| Randy Messenger |   | mr | 25 | 5 | 1 | .200 | 4 | .800 | 11 | 39 | 19 | .487 | 60 | 60 | 21 |
| Dan Meyer* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 6 | 3 | 2 |
| Andrew Miller* | GEO | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Jason Miller* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 1 |
| Justin Miller |   | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 18 | 27 | 8 | .296 | 62 | 62 | 10 |
| Matt Miller |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 2 | 2 | 2 |
| Trever Miller* |   | mr | 34 | 3 | 1 | .333 | 2 | .667 | 12 | 48 | 11 | .229 | 76 | 76 | 12 |
| Wade Miller |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Kevin Millwood |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Eric Milton* |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Zach Miner |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 9 | 24 | 6 | .250 | 34 | 33 | 8 |
| Patrick Misch* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 7 | .583 | 18 | 14 | 2 |
| Sergio Mitre |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Brian Moehler |   | mr | 35 | 1 | 1 | 1.000 | 0 | .000 | 1 | 13 | 2 | .154 | 42 | 42 | 29 |
| Franklin Morales* |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Juan Morillo |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 1 |
| Matt Morris |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Brandon Morrow | CRH | mr | 22 | 2 | 0 | .000 | 2 | 1.000 | 18 | 40 | 11 | .275 | 60 | 60 | 18 |
| Dustin Moseley |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 4 | 11 | 0 | .000 | 46 | 38 | 13 |
| Guillermo Mota |   | mr | 33 | 3 | 0 | .000 | 3 | 1.000 | 6 | 16 | 5 | .313 | 52 | 52 | 10 |
| Jamie Moyer* |   | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Peter Moylan | MAD | mr | 28 | 2 | 1 | .500 | 1 | .500 | 9 | 47 | 13 | .277 | 80 | 80 | 16 |
| Edward Mujica |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 10 | 10 | 5 |
| Mark Mulder* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Carlos Muniz |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Arnie Munoz* |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 4 | 16 | 3 | .188 | 13 | 13 | 0 |
| Scott Munter |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 15 | 8 | .533 | 12 | 12 | 5 |
| Bill Murphy* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 4 | .571 | 10 | 10 | 2 |
| A.J. Murray* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 2 | .400 | 14 | 12 | 6 |
| Neal Musser* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 5 | .455 | 17 | 17 | 3 |
| Mike Mussina |   | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 0 |
| Brett Myers | CRH | cl | 26 | 24 | 21 | .875 | 3 | .125 | 3 | 6 | 3 | .500 | 51 | 48 | 37 |
| Mike Myers* |   | mr | 38 | 5 | 0 | .000 | 5 | 1.000 | 6 | 67 | 26 | .388 | 72 | 72 | 14 |
| Joe Nathan | WIZ | cl | 32 | 41 | 37 | .902 | 4 | .098 | 0 | 8 | 3 | .375 | 68 | 68 | 60 |
| Pat Neshek | BON | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 15 | 59 | 14 | .237 | 74 | 74 | 20 |
| Josh Newman* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 2 |
| Dustin Nippert |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 2 | 17 | 7 | .412 | 36 | 36 | 8 |
| Ricky Nolasco |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 0 |
| Leo Nunez |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 0 | .000 | 13 | 7 | 2 |
| Eric O'Flaherty* | CRH | mr | 22 | 2 | 0 | .000 | 2 | 1.000 | 4 | 56 | 13 | .232 | 56 | 56 | 9 |
| Wes Obermueller |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 18 | 11 | 4 |
| Tomo Ohka |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Ross Ohlendorf |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 6 | 6 | 3 |
| Will Ohman* | MAD | mr | 29 | 2 | 1 | .500 | 1 | .500 | 12 | 46 | 11 | .239 | 56 | 56 | 11 |
| Hideki Okajima* | COP | mr | 31 | 7 | 5 | .714 | 2 | .286 | 27 | 28 | 4 | .143 | 66 | 66 | 13 |
| Darren Oliver* |   | mr | 36 | 2 | 0 | .000 | 2 | 1.000 | 8 | 31 | 13 | .419 | 61 | 61 | 20 |
| Scott Olsen* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Garrett Olson* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Ramon Ortiz |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 16 | 11 | .688 | 38 | 28 | 15 |
| Russ Ortiz |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 12 | 4 | 1 |
| Chad Orvella |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 10 | 10 | 0 |
| Franquelis Osoria |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 4 | 18 | 7 | .389 | 25 | 25 | 3 |
| Roy Oswalt | BT | sp | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 33 | 1 | 0 |
| Akinori Otsuka |   | mr | 35 | 7 | 4 | .571 | 3 | .429 | 11 | 1 | 0 | .000 | 34 | 34 | 13 |
| Henry Owens |   | mr | 28 | 5 | 4 | .800 | 1 | .200 | 5 | 2 | 0 | .000 | 22 | 22 | 10 |
| Micah Owings |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 29 | 2 | 0 |
| Vicente Padilla |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 |
| Jonathan Papelbon | BON | cl | 26 | 40 | 37 | .925 | 3 | .075 | 2 | 19 | 5 | .263 | 59 | 59 | 53 |
| Chan Ho Park |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Chad Paronto |   | mr | 31 | 2 | 1 | .500 | 1 | .500 | 2 | 25 | 8 | .320 | 41 | 41 | 12 |
| Manny Parra* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 3 | .500 | 9 | 7 | 3 |
| John Parrish* |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 10 | 38 | 16 | .421 | 53 | 53 | 14 |
| John Patterson |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Troy Patton* |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 1 |
| Felipe Paulino |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 5 | 2 | 0 |
| Carl Pavano |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Jake Peavy | MUL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jailen Peguero |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 3 | 6 | 2 | .333 | 18 | 18 | 6 |
| Mike Pelfrey |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 15 | 2 | 0 |
| Tony Pena | LON | mr | 25 | 5 | 2 | .400 | 3 | .600 | 30 | 38 | 10 | .263 | 75 | 75 | 13 |
| Brad Penny | LON | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Joel Peralta | MID | mr | 31 | 5 | 1 | .200 | 4 | .800 | 7 | 57 | 16 | .281 | 62 | 62 | 18 |
| Troy Percival | OTR | mr | 37 | 0 | 0 | .000 | 0 | .000 | 5 | 9 | 3 | .333 | 34 | 33 | 9 |
| Juan Perez* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 2 | .222 | 17 | 17 | 4 |
| Odalis Perez* |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Oliver Perez* | BT | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Rafael Perez* | CRH | mr | 25 | 2 | 1 | .500 | 1 | .500 | 12 | 37 | 6 | .162 | 44 | 44 | 11 |
| Glen Perkins* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 3 | 10 | 2 | .200 | 19 | 19 | 3 |
| Yusmeiro Petit |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 4 | 2 |
| Billy Petrick |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 8 | 8 | 1 |
| Andy Pettitte* |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 36 | 2 | 0 |
| Heath Phillips* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 6 | 6 | 5 |
| Carmen Pignatiello* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 4 | 4 | 0 |
| Joel Pineiro |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 42 | 31 | 15 |
| Renyel Pinto* |   | mr | 24 | 6 | 1 | .167 | 5 | .833 | 18 | 38 | 8 | .211 | 57 | 57 | 4 |
| Sidney Ponson |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 |
| Bret Prinz |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 1 |
| Scott Proctor |   | mr | 30 | 7 | 0 | .000 | 7 | 1.000 | 18 | 42 | 11 | .262 | 83 | 83 | 14 |
| J.J. Putz | MID | cl | 30 | 42 | 40 | .952 | 2 | .048 | 0 | 32 | 7 | .219 | 68 | 68 | 65 |
| Chad Qualls | BON | mr | 28 | 11 | 5 | .455 | 6 | .545 | 21 | 31 | 8 | .258 | 79 | 79 | 16 |
| Aaron Rakers |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Edwar Ramirez |   | mr | 26 | 3 | 1 | .333 | 2 | .667 | 3 | 18 | 9 | .500 | 21 | 21 | 5 |
| Elizardo Ramirez |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 0 |
| Erasmo Ramirez* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 7 | 7 | 3 |
| Horacio Ramirez* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Ramon Ramirez | LON | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 14 | 5 | .357 | 22 | 22 | 5 |
| Stephen Randolph* |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 14 | 14 | 4 |
| Clay Rapada* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 5 | 5 | 2 |
| Darrell Rasner |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Jon Rauch | TON | mr | 28 | 10 | 4 | .400 | 6 | .600 | 33 | 23 | 6 | .261 | 88 | 88 | 26 |
| Chris Ray | MID | cl | 25 | 20 | 16 | .800 | 4 | .200 | 0 | 8 | 5 | .625 | 43 | 43 | 37 |
| Tim Redding | CCL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Mark Redman* |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 11 | 3 | 0 |
| Chris Reitsma |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 6 | 12 | 5 | .417 | 26 | 26 | 6 |
| Chris Resop |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 4 | 4 | 3 |
| Al Reyes |   | cl | 37 | 30 | 26 | .867 | 4 | .133 | 0 | 7 | 3 | .429 | 61 | 61 | 52 |
| Anthony Reyes |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 2 | 1 |
| Dennys Reyes* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 8 | 35 | 8 | .229 | 50 | 50 | 7 |
| Jo-Jo Reyes* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 11 | 1 | 0 |
| John Rheinecker* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 3 | 11 | 3 | .273 | 23 | 16 | 0 |
| Jeff Ridgway* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 0 |
| Juan Rincon |   | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 14 | 30 | 12 | .400 | 63 | 63 | 16 |
| Royce Ring* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 22 | 7 | .318 | 26 | 26 | 7 |
| David Riske | CRH | mr | 30 | 8 | 4 | .500 | 4 | .500 | 16 | 38 | 11 | .289 | 65 | 65 | 27 |
| Mariano Rivera | ROK | cl | 37 | 34 | 30 | .882 | 4 | .118 | 0 | 26 | 7 | .269 | 67 | 67 | 59 |
| Saul Rivera | BT | mr | 29 | 6 | 3 | .500 | 3 | .500 | 21 | 49 | 11 | .224 | 85 | 85 | 17 |
| Connor Robertson |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 0 |
| Nate Robertson* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Fernando Rodney | OTR | mr | 30 | 3 | 1 | .333 | 2 | .667 | 12 | 13 | 2 | .154 | 48 | 48 | 12 |
| Francisco Rodriguez | BON | cl | 25 | 46 | 40 | .870 | 6 | .130 | 0 | 17 | 7 | .412 | 64 | 64 | 56 |
| Wandy Rodriguez* | MUL | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Brian Rogers |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 3 | 3 | 1 |
| Kenny Rogers* |   | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 |
| J.C. Romero* |   | mr | 31 | 2 | 1 | .500 | 1 | .500 | 24 | 41 | 8 | .195 | 74 | 74 | 10 |
| Francisco Rosario |   | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 3 | 3 | 1.000 | 23 | 23 | 10 |
| Ryan Rowland-Smith* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 3 | 25 | 13 | .520 | 26 | 26 | 6 |
| B.J. Ryan* |   | cl | 31 | 5 | 3 | .600 | 2 | .400 | 0 | 0 | 0 | .000 | 5 | 5 | 4 |
| Jae Kuk Ryu |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 3 | 3 | 1.000 | 17 | 17 | 7 |
| Kirk Saarloos |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 4 | 16 | 4 | .250 | 34 | 31 | 7 |
| C.C. Sabathia* | CRH | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Takashi Saito | Pal | cl | 37 | 43 | 39 | .907 | 4 | .093 | 1 | 12 | 4 | .333 | 63 | 63 | 55 |
| Juan Salas |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 2 | 20 | 8 | .400 | 34 | 34 | 10 |
| Brad Salmon |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 18 | 6 | .333 | 26 | 26 | 9 |
| Chris Sampson |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 24 | 5 | 2 |
| Brian Sanches |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 3 | .500 | 12 | 12 | 4 |
| Anibal Sanchez | MAD | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Jonathan Sanchez* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 2 | .154 | 33 | 29 | 8 |
| Romulo Sanchez |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 2 | .500 | 16 | 16 | 7 |
| Ervin Santana | BON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 2 | 1 |
| Johan Santana* | ROK | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Victor Santos |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 2 | 21 | 11 | .524 | 36 | 33 | 12 |
| Dennis Sarfate |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 3 | 2 | 0 | .000 | 7 | 7 | 1 |
| Joe Saunders* | MID | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 |
| Curt Schilling | Pal | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Jason Schmidt |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Scott Schoeneweis* |   | mr | 33 | 3 | 2 | .667 | 1 | .333 | 11 | 43 | 7 | .163 | 70 | 70 | 17 |
| Chris Schroder | CCL | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 21 | 3 | .143 | 37 | 37 | 8 |
| Mike Schultz |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 |
| Rudy Seanez |   | mr | 38 | 3 | 1 | .333 | 2 | .667 | 4 | 39 | 16 | .410 | 73 | 73 | 19 |
| Bobby Seay* | ROK | mr | 29 | 2 | 1 | .500 | 1 | .500 | 12 | 42 | 6 | .143 | 58 | 58 | 19 |
| Chris Seddon* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 3 | 1 |
| Zack Segovia |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Aaron Sele |   | mr | 37 | 0 | 0 | .000 | 0 | .000 | 2 | 24 | 5 | .208 | 34 | 34 | 10 |
| Jae Seo |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 1 | 1 |
| Dan Serafini* |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 3 | 0 |
| Josh Sharpless |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 3 | 1.000 | 6 | 6 | 2 |
| Tom Shearn |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 7 | 1 | 0 |
| Ben Sheets | TON | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| George Sherrill* | ROK | mr | 30 | 7 | 3 | .429 | 4 | .571 | 22 | 71 | 16 | .225 | 73 | 73 | 16 |
| James Shields | BON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Scot Shields | ROK | mr | 31 | 8 | 2 | .250 | 6 | .750 | 31 | 32 | 12 | .375 | 71 | 71 | 13 |
| Brian Shouse* | OTR | mr | 38 | 4 | 1 | .250 | 3 | .750 | 21 | 78 | 18 | .231 | 73 | 73 | 13 |
| Paul Shuey |   | mr | 36 | 1 | 1 | 1.000 | 0 | .000 | 6 | 8 | 1 | .125 | 25 | 25 | 5 |
| Carlos Silva | MID | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jason Simontacchi |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Andrew Sisco* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 4 | 14 | 3 | .214 | 19 | 19 | 6 |
| Doug Slaten* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 7 | 36 | 12 | .333 | 61 | 61 | 13 |
| Kevin Slowey |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 13 | 2 | 0 |
| Joe Smith | LON | mr | 23 | 0 | 0 | .000 | 0 | .000 | 10 | 51 | 25 | .490 | 54 | 54 | 14 |
| Matt Smith* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 3 | 4 | 0 | .000 | 9 | 9 | 0 |
| John Smoltz | WIZ | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Ian Snell |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Kyle Snyder |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 1 | 19 | 6 | .316 | 46 | 46 | 17 |
| Andy Sonnanstine |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Joakim Soria | BON | cl | 23 | 21 | 17 | .810 | 4 | .190 | 9 | 26 | 4 | .154 | 62 | 62 | 38 |
| Rafael Soriano | GEO | mr | 27 | 12 | 9 | .750 | 3 | .250 | 19 | 12 | 2 | .167 | 71 | 71 | 28 |
| Jorge Sosa |   | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 9 | 27 | 10 | .370 | 42 | 28 | 2 |
| Jeremy Sowers* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Justin Speier | MID | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 24 | 36 | 6 | .167 | 51 | 51 | 9 |
| Ryan Speier |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 4 | 12 | 1 | .083 | 20 | 20 | 5 |
| Levale Speigner |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 7 | .538 | 19 | 13 | 3 |
| Russ Springer | WIZ | mr | 38 | 2 | 0 | .000 | 2 | 1.000 | 11 | 28 | 7 | .250 | 76 | 76 | 18 |
| Chris Spurling |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 2 | 22 | 11 | .500 | 49 | 49 | 21 |
| Jason Standridge |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 4 | 4 | 2 |
| Jason Stanford* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 5 | .833 | 8 | 6 | 2 |
| Mike Stanton* |   | mr | 40 | 3 | 0 | .000 | 3 | 1.000 | 10 | 51 | 18 | .353 | 69 | 69 | 11 |
| Tim Stauffer | MAD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Mitch Stetter* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 6 | 2 |
| Brian Stokes |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 8 | 29 | 12 | .414 | 59 | 59 | 22 |
| Ricky Stone |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 5 | 5 | 3 |
| Huston Street | GEO | cl | 23 | 21 | 16 | .762 | 5 | .238 | 5 | 5 | 2 | .400 | 48 | 48 | 35 |
| Eric Stults* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 12 | 7 | 0 |
| Jeff Suppan |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jon Switzer* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 3 | 13 | 4 | .308 | 21 | 21 | 2 |
| Brian Tallet* | EDG | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 2 | 35 | 16 | .457 | 48 | 48 | 11 |
| Taylor Tankersley* |   | mr | 24 | 3 | 1 | .333 | 2 | .667 | 16 | 50 | 10 | .200 | 67 | 67 | 12 |
| Jack Taschner* |   | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 14 | 44 | 15 | .341 | 63 | 63 | 16 |
| Jordan Tata |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Ty Taubenheim |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Julian Tavarez |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 1 | .143 | 34 | 11 | 2 |
| Robinson Tejeda |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 |
| Joe Thatcher* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 20 | 4 | .200 | 22 | 22 | 5 |
| Brad Thompson |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 6 | .667 | 44 | 27 | 10 |
| Mike Thompson |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 6 | .667 | 7 | 7 | 4 |
| Rich Thompson |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 7 | 7 | 2 |
| John Thomson |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Matt Thornton* | CRH | mr | 30 | 7 | 2 | .286 | 5 | .714 | 17 | 63 | 20 | .317 | 68 | 68 | 13 |
| Erick Threets* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Mike Timlin | OTR | mr | 41 | 2 | 1 | .500 | 1 | .500 | 8 | 25 | 6 | .240 | 50 | 50 | 19 |
| Brett Tomko |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 5 | .417 | 40 | 21 | 9 |
| Salomon Torres |   | mr | 35 | 18 | 12 | .667 | 6 | .333 | 5 | 17 | 4 | .235 | 56 | 56 | 28 |
| Josh Towers |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 25 | 10 | 6 |
| Billy Traber* |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 2 | 16 | 10 | .625 | 28 | 26 | 5 |
| Steve Trachsel |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Chin-hui Tsao |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 3 | 14 | 1 | .071 | 21 | 21 | 6 |
| Derrick Turnbow | MAD | mr | 29 | 4 | 1 | .250 | 3 | .750 | 33 | 14 | 12 | .857 | 77 | 77 | 13 |
| Lino Urdaneta |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 0 |
| Jose Valverde | WIZ | cl | 27 | 54 | 47 | .870 | 7 | .130 | 0 | 7 | 2 | .286 | 65 | 65 | 59 |
| John Van Benschoten |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 2 | 1 |
| Rick VandenHurk |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 18 | 1 | 0 |
| Claudio Vargas |   | sp | 29 | 2 | 1 | .500 | 1 | .500 | 0 | 0 | 0 | .000 | 29 | 6 | 1 |
| Jason Vargas* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Virgil Vasquez |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 2 | 0 |
| Javier Vazquez | Pal | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jose Veras |   | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 1 | 0 | 0 | .000 | 9 | 9 | 3 |
| Justin Verlander | COP | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jamie Vermilyea |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Carlos Villanueva | TON | mr | 23 | 3 | 1 | .333 | 2 | .667 | 16 | 22 | 10 | .455 | 59 | 53 | 8 |
| Oscar Villarreal |   | mr | 25 | 4 | 1 | .250 | 3 | .750 | 2 | 33 | 14 | .424 | 51 | 51 | 11 |
| Ron Villone* |   | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 4 | 28 | 12 | .429 | 37 | 37 | 13 |
| Luis Vizcaino | LON | mr | 32 | 3 | 0 | .000 | 3 | 1.000 | 15 | 52 | 17 | .327 | 77 | 77 | 13 |
| Edinson Volquez |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Billy Wagner* | BT | cl | 35 | 39 | 34 | .872 | 5 | .128 | 0 | 3 | 2 | .667 | 66 | 66 | 57 |
| Ryan Wagner |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 4 | .400 | 14 | 14 | 2 |
| Adam Wainwright | MAD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Tim Wakefield | OTR | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Jamie Walker* | OTR | mr | 35 | 13 | 7 | .538 | 6 | .462 | 21 | 53 | 22 | .415 | 81 | 81 | 19 |
| Tyler Walker |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 7 | 8 | 3 | .375 | 15 | 15 | 1 |
| Chien-Ming Wang | MID | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| John Wasdin |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 12 | 12 | 4 |
| Jarrod Washburn* |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Ehren Wassermann |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 9 | 27 | 9 | .333 | 33 | 33 | 6 |
| David Weathers | TON | cl | 37 | 39 | 33 | .846 | 6 | .154 | 0 | 27 | 8 | .296 | 70 | 70 | 60 |
| Jeff Weaver |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Jered Weaver | OTR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Brandon Webb | TON | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Todd Wellemeyer |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 10 | 2 | .200 | 32 | 21 | 7 |
| David Wells* |   | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Kip Wells |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 3 | 0 | 0 | .000 | 34 | 8 | 4 |
| Jake Westbrook | MID | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Dan Wheeler | Pal | mr | 29 | 18 | 11 | .611 | 7 | .389 | 18 | 19 | 10 | .526 | 70 | 70 | 29 |
| Bill White* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 3 | 4 | 1 | .250 | 9 | 9 | 1 |
| Rick White |   | mr | 38 | 1 | 0 | .000 | 1 | 1.000 | 4 | 23 | 8 | .348 | 29 | 29 | 7 |
| Sean White |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 18 | 4 | .222 | 15 | 15 | 4 |
| Bob Wickman |   | cl | 38 | 26 | 20 | .769 | 6 | .231 | 1 | 16 | 7 | .438 | 57 | 57 | 40 |
| Dave Williams* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 1 |
| Jerome Williams |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Todd Williams |   | mr | 36 | 1 | 0 | .000 | 1 | 1.000 | 3 | 8 | 5 | .625 | 14 | 14 | 5 |
| Woody Williams |   | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 33 | 2 | 0 |
| Scott Williamson |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 1 | 14 | 3 | .214 | 16 | 16 | 2 |
| Dontrelle Willis* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 |
| Brian Wilson |   | cl | 25 | 7 | 6 | .857 | 1 | .143 | 9 | 3 | 0 | .000 | 24 | 24 | 9 |
| C.J. Wilson* | ROK | mr | 26 | 14 | 12 | .857 | 2 | .143 | 15 | 47 | 15 | .319 | 66 | 66 | 22 |
| Matt Wise |   | mr | 31 | 2 | 1 | .500 | 1 | .500 | 13 | 32 | 11 | .344 | 56 | 56 | 9 |
| Jay Witasick |   | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 4 | 11 | 3 | .273 | 36 | 36 | 10 |
| Randy Wolf* | CCL | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 |
| Ross Wolf |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 3 | .250 | 14 | 14 | 2 |
| Brian Wolfe | OTR | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 6 | 27 | 12 | .444 | 38 | 38 | 12 |
| Kerry Wood | MUL | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 22 | 22 | 2 |
| Mike Wood |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 3 | 13 | 7 | .538 | 21 | 17 | 3 |
| Jake Woods* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 4 | 4 | 2 |
| Chase Wright* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 0 |
| Jamey Wright |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 2 | .333 | 20 | 11 | 3 |
| Jaret Wright |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Michael Wuertz | BT | mr | 28 | 0 | 0 | .000 | 0 | .000 | 8 | 38 | 5 | .132 | 73 | 73 | 19 |
| Tyler Yates |   | mr | 29 | 3 | 2 | .667 | 1 | .333 | 13 | 29 | 8 | .276 | 75 | 75 | 14 |
| Shane Youman* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 16 | 8 | 3 |
| Chris Young | COP | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Mike Zagurski* |   | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 5 | 17 | 10 | .588 | 25 | 25 | 4 |
| Carlos Zambrano | CCL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Victor Zambrano |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 6 | 1.000 | 13 | 9 | 2 |
| Mauro Zarate |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 4 | 4 | 0 |
| Barry Zito* | EDG | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 0 |
| Joel Zumaya |   | mr | 22 | 5 | 1 | .200 | 4 | .800 | 8 | 20 | 6 | .300 | 28 | 28 | 7 |