Real-life pitching register -- All players in database
Regular season
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | BT | mr | 24 | 4.08 | 3 | 0 | 0 | 45 | 0 | 0 | 0 | 53.0 | 41 | 25 | 24 | 28 | 49 | 9 | 2 |
| Winston Abreu |   | mr | 29 | 10.13 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.0 | 10 | 10 | 9 | 6 | 6 | 1 | 0 |
| Jeremy Accardo |   | mr | 24 | 5.35 | 2 | 4 | 3 | 65 | 0 | 0 | 0 | 69.0 | 76 | 42 | 41 | 20 | 54 | 7 | 3 |
| Mike Adams | MUL | mr | 27 | 11.57 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 4 | 3 | 3 | 2 | 1 | 1 | 0 |
| Jon Adkins |   | mr | 28 | 3.98 | 2 | 1 | 0 | 55 | 0 | 0 | 0 | 54.1 | 55 | 26 | 24 | 20 | 30 | 3 | 8 |
| Jeremy Affeldt* | CRH | mr | 27 | 6.20 | 8 | 8 | 1 | 54 | 9 | 0 | 0 | 97.1 | 102 | 74 | 67 | 55 | 48 | 13 | 8 |
| Matt Albers |   | sp | 23 | 6.00 | 0 | 2 | 0 | 4 | 2 | 0 | 0 | 15.0 | 17 | 10 | 10 | 7 | 11 | 1 | 3 |
| Antonio Alfonseca |   | mr | 34 | 5.63 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 16.0 | 23 | 10 | 10 | 7 | 5 | 3 | 3 |
| Abe Alvarez* |   | mr | 23 | 12.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.0 | 5 | 4 | 4 | 2 | 2 | 2 | 1 |
| Steve Andrade |   | mr | 28 | 9.64 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.2 | 5 | 5 | 5 | 4 | 5 | 0 | 0 |
| Greg Aquino |   | mr | 28 | 4.47 | 2 | 0 | 0 | 42 | 0 | 0 | 0 | 48.1 | 54 | 27 | 24 | 24 | 51 | 8 | 7 |
| Tony Armas |   | sp | 28 | 5.03 | 9 | 12 | 0 | 30 | 30 | 0 | 0 | 154.0 | 167 | 96 | 86 | 64 | 97 | 19 | 14 |
| Bronson Arroyo | BT | sp | 29 | 3.29 | 14 | 11 | 0 | 35 | 35 | 3 | 1 | 240.2 | 222 | 98 | 88 | 64 | 184 | 31 | 14 |
| Miguel Asencio |   | mr | 25 | 4.70 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 7.2 | 9 | 8 | 4 | 4 | 7 | 1 | 1 |
| Ezequiel Astacio |   | mr | 26 | 11.12 | 2 | 0 | 0 | 6 | 0 | 0 | 0 | 5.2 | 7 | 7 | 7 | 6 | 6 | 2 | 0 |
| Pedro Astacio |   | sp | 36 | 5.98 | 5 | 5 | 0 | 17 | 17 | 1 | 1 | 90.1 | 109 | 64 | 60 | 31 | 42 | 14 | 6 |
| Brandon Backe |   | sp | 28 | 3.77 | 3 | 2 | 0 | 8 | 8 | 0 | 0 | 43.0 | 43 | 18 | 18 | 18 | 19 | 4 | 3 |
| Cha Seung Baek |   | sp | 26 | 3.67 | 4 | 1 | 0 | 6 | 6 | 0 | 0 | 34.1 | 26 | 15 | 14 | 13 | 23 | 6 | 1 |
| Danys Baez |   | mr | 28 | 4.53 | 5 | 6 | 9 | 57 | 0 | 0 | 0 | 59.2 | 60 | 35 | 30 | 17 | 39 | 3 | 5 |
| Jeff Bajenaru |   | mr | 28 | 36.00 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1.0 | 4 | 4 | 4 | 0 | 0 | 3 | 0 |
| Scott Baker |   | sp | 24 | 6.37 | 5 | 8 | 0 | 16 | 16 | 0 | 0 | 83.1 | 114 | 63 | 59 | 16 | 62 | 17 | 4 |
| Brian Bannister |   | sp | 25 | 4.26 | 2 | 1 | 0 | 8 | 6 | 0 | 0 | 38.0 | 34 | 18 | 18 | 22 | 19 | 4 | 1 |
| Kevin Barry |   | mr | 27 | 5.61 | 1 | 1 | 0 | 19 | 1 | 0 | 0 | 25.2 | 24 | 16 | 16 | 14 | 19 | 2 | 0 |
| Phil Barzilla* |   | mr | 27 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Miguel Batista |   | sp | 35 | 4.58 | 11 | 8 | 0 | 34 | 33 | 3 | 1 | 206.1 | 231 | 116 | 105 | 84 | 110 | 18 | 32 |
| Rick Bauer | EDG | mr | 29 | 3.55 | 3 | 1 | 2 | 58 | 1 | 0 | 0 | 71.0 | 73 | 31 | 28 | 25 | 35 | 4 | 12 |
| Denny Bautista |   | sp | 23 | 5.62 | 0 | 3 | 0 | 12 | 8 | 0 | 0 | 41.2 | 47 | 34 | 26 | 21 | 27 | 5 | 2 |
| Jonah Bayliss |   | mr | 25 | 4.30 | 1 | 1 | 0 | 11 | 0 | 0 | 0 | 14.2 | 13 | 7 | 7 | 11 | 15 | 1 | 0 |
| T.J. Beam |   | mr | 25 | 8.50 | 2 | 0 | 0 | 20 | 0 | 0 | 0 | 18.0 | 26 | 17 | 17 | 6 | 12 | 5 | 2 |
| Colter Bean |   | mr | 29 | 9.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 2 | 2 | 2 | 1 | 0 | 1 |
| Josh Beckett | Pal | sp | 26 | 5.01 | 16 | 11 | 0 | 33 | 33 | 0 | 0 | 204.2 | 191 | 120 | 114 | 74 | 158 | 36 | 20 |
| Erik Bedard* | GEO | sp | 27 | 3.76 | 15 | 11 | 0 | 33 | 33 | 0 | 0 | 196.1 | 196 | 92 | 82 | 69 | 171 | 16 | 17 |
| Joe Beimel* |   | mr | 29 | 2.96 | 2 | 1 | 2 | 62 | 0 | 0 | 0 | 70.0 | 70 | 26 | 23 | 21 | 30 | 7 | 10 |
| Matt Belisle |   | mr | 26 | 3.60 | 2 | 0 | 0 | 30 | 2 | 0 | 0 | 40.0 | 43 | 18 | 16 | 19 | 26 | 5 | 5 |
| Heath Bell | MUL | mr | 28 | 5.11 | 0 | 0 | 0 | 22 | 0 | 0 | 0 | 37.0 | 51 | 25 | 21 | 11 | 35 | 6 | 6 |
| Armando Benitez |   | cl | 33 | 3.52 | 4 | 2 | 17 | 41 | 0 | 0 | 0 | 38.1 | 39 | 15 | 15 | 21 | 31 | 6 | 3 |
| Joaquin Benoit | OTR | mr | 28 | 4.86 | 1 | 1 | 0 | 56 | 0 | 0 | 0 | 79.2 | 68 | 49 | 43 | 38 | 85 | 5 | 4 |
| Kris Benson |   | sp | 31 | 4.82 | 11 | 12 | 0 | 30 | 30 | 3 | 0 | 183.0 | 199 | 105 | 98 | 58 | 88 | 33 | 19 |
| Jason Bergmann |   | mr | 24 | 6.68 | 0 | 2 | 0 | 29 | 6 | 0 | 0 | 64.2 | 81 | 49 | 48 | 27 | 54 | 12 | 1 |
| Adam Bernero |   | sp | 29 | 6.00 | 1 | 1 | 0 | 4 | 3 | 0 | 0 | 15.0 | 22 | 10 | 10 | 2 | 12 | 3 | 1 |
| Rafael Betancourt | GEO | mr | 31 | 3.81 | 3 | 4 | 3 | 50 | 0 | 0 | 0 | 56.2 | 52 | 25 | 24 | 11 | 48 | 7 | 2 |
| Chad Billingsley | TON | sp | 21 | 3.80 | 7 | 4 | 0 | 18 | 16 | 0 | 0 | 90.0 | 92 | 43 | 38 | 58 | 59 | 7 | 12 |
| Kurt Birkins* |   | mr | 25 | 4.94 | 5 | 2 | 0 | 35 | 0 | 0 | 0 | 31.0 | 25 | 19 | 17 | 16 | 27 | 4 | 2 |
| Joe Blanton | BON | sp | 25 | 4.82 | 16 | 12 | 0 | 32 | 31 | 1 | 1 | 194.1 | 241 | 111 | 104 | 58 | 107 | 17 | 20 |
| Jeremy Bonderman | OTR | sp | 23 | 4.08 | 14 | 8 | 0 | 34 | 34 | 0 | 0 | 214.0 | 214 | 104 | 97 | 64 | 202 | 18 | 20 |
| Boof Bonser | BON | sp | 24 | 4.22 | 7 | 6 | 0 | 18 | 18 | 0 | 0 | 100.1 | 104 | 50 | 47 | 24 | 84 | 18 | 9 |
| Chris Booker |   | mr | 29 | 9.72 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 8.1 | 10 | 9 | 9 | 4 | 7 | 4 | 1 |
| Chris Bootcheck |   | mr | 27 | 10.45 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 10.1 | 16 | 12 | 12 | 9 | 7 | 3 | 4 |
| Dave Borkowski |   | mr | 29 | 4.69 | 3 | 2 | 0 | 40 | 0 | 0 | 0 | 71.0 | 70 | 38 | 37 | 23 | 52 | 8 | 5 |
| Joe Borowski |   | cl | 35 | 3.75 | 3 | 3 | 36 | 72 | 0 | 0 | 0 | 69.2 | 63 | 31 | 29 | 33 | 64 | 7 | 3 |
| Micah Bowie* |   | mr | 31 | 1.37 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 19.2 | 11 | 3 | 3 | 7 | 11 | 1 | 1 |
| Blaine Boyer |   | mr | 24 | 40.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.2 | 4 | 3 | 3 | 1 | 0 | 0 | 0 |
| Chad Bradford | EDG | mr | 31 | 2.90 | 4 | 2 | 2 | 70 | 0 | 0 | 0 | 62.0 | 59 | 22 | 20 | 13 | 45 | 1 | 6 |
| Ryan Braun |   | mr | 25 | 6.75 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 10.2 | 13 | 8 | 8 | 3 | 6 | 2 | 1 |
| Bill Bray* |   | mr | 23 | 4.09 | 3 | 2 | 2 | 48 | 0 | 0 | 0 | 50.2 | 57 | 27 | 23 | 18 | 39 | 5 | 7 |
| Dewon Brazelton |   | mr | 26 | 12.00 | 0 | 2 | 0 | 9 | 2 | 0 | 0 | 18.0 | 28 | 25 | 24 | 9 | 9 | 6 | 0 |
| Yhency Brazoban |   | mr | 26 | 5.40 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 5.0 | 7 | 3 | 3 | 2 | 4 | 0 | 0 |
| Craig Breslow* |   | mr | 25 | 3.75 | 0 | 2 | 0 | 13 | 0 | 0 | 0 | 12.0 | 12 | 5 | 5 | 6 | 12 | 0 | 0 |
| Eude Brito* |   | mr | 27 | 7.36 | 1 | 2 | 0 | 5 | 2 | 0 | 0 | 18.1 | 21 | 15 | 15 | 12 | 9 | 2 | 1 |
| Chris Britton | OTR | mr | 23 | 3.35 | 0 | 2 | 1 | 52 | 0 | 0 | 0 | 53.2 | 46 | 22 | 20 | 17 | 41 | 4 | 2 |
| Doug Brocail |   | mr | 39 | 4.76 | 2 | 2 | 0 | 25 | 0 | 0 | 0 | 28.1 | 27 | 16 | 15 | 8 | 19 | 1 | 1 |
| Jim Brower |   | mr | 33 | 12.15 | 0 | 1 | 0 | 18 | 0 | 0 | 0 | 20.0 | 32 | 27 | 27 | 14 | 14 | 2 | 3 |
| Andrew Brown |   | mr | 25 | 3.60 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 10.0 | 6 | 4 | 4 | 8 | 7 | 0 | 1 |
| Jonathan Broxton | CCL | mr | 22 | 2.59 | 4 | 1 | 3 | 68 | 0 | 0 | 0 | 76.1 | 61 | 25 | 22 | 33 | 97 | 7 | 7 |
| Brian Bruney |   | mr | 24 | 0.87 | 1 | 1 | 0 | 19 | 0 | 0 | 0 | 20.2 | 14 | 2 | 2 | 15 | 25 | 1 | 1 |
| Taylor Buchholz | MUL | sp | 24 | 5.89 | 6 | 10 | 0 | 22 | 19 | 1 | 1 | 113.0 | 107 | 80 | 74 | 34 | 77 | 21 | 9 |
| Mark Buehrle* | GEO | sp | 27 | 4.99 | 12 | 13 | 0 | 32 | 32 | 1 | 0 | 204.0 | 247 | 124 | 113 | 48 | 98 | 36 | 21 |
| Jason Bulger |   | mr | 27 | 16.20 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.2 | 1 | 3 | 3 | 3 | 1 | 0 | 0 |
| Ambiorix Burgos |   | cl | 22 | 5.52 | 4 | 5 | 18 | 68 | 1 | 0 | 0 | 73.1 | 83 | 49 | 45 | 37 | 72 | 16 | 10 |
| A.J. Burnett | TON | sp | 29 | 3.98 | 10 | 8 | 0 | 21 | 21 | 2 | 1 | 135.2 | 138 | 67 | 60 | 39 | 118 | 14 | 15 |
| Mike Burns |   | mr | 27 | 7.29 | 0 | 0 | 0 | 18 | 0 | 0 | 0 | 21.0 | 40 | 17 | 17 | 4 | 16 | 2 | 4 |
| Brian Burres* |   | mr | 25 | 2.25 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 8.0 | 6 | 2 | 2 | 1 | 6 | 1 | 0 |
| Dave Bush | OTR | sp | 26 | 4.41 | 12 | 11 | 0 | 34 | 32 | 3 | 2 | 210.0 | 201 | 111 | 103 | 38 | 166 | 26 | 8 |
| Paul Byrd |   | sp | 35 | 4.88 | 10 | 9 | 0 | 31 | 31 | 1 | 0 | 179.0 | 232 | 120 | 97 | 38 | 88 | 26 | 12 |
| Tim Byrdak* |   | mr | 32 | 12.86 | 1 | 0 | 0 | 16 | 0 | 0 | 0 | 7.0 | 14 | 10 | 10 | 8 | 2 | 2 | 2 |
| Daniel Cabrera | CRH | sp | 25 | 4.74 | 9 | 10 | 0 | 26 | 26 | 2 | 1 | 148.0 | 130 | 82 | 78 | 104 | 157 | 11 | 20 |
| Fernando Cabrera |   | mr | 24 | 5.19 | 3 | 3 | 0 | 51 | 0 | 0 | 0 | 60.2 | 53 | 36 | 35 | 32 | 71 | 12 | 4 |
| Matt Cain | LON | sp | 21 | 4.15 | 13 | 12 | 0 | 32 | 31 | 1 | 1 | 190.2 | 157 | 93 | 88 | 87 | 179 | 18 | 6 |
| Kiko Calero | LON | mr | 31 | 3.41 | 3 | 2 | 2 | 70 | 0 | 0 | 0 | 58.0 | 50 | 22 | 22 | 24 | 67 | 4 | 2 |
| Shawn Camp |   | mr | 30 | 4.68 | 7 | 4 | 4 | 75 | 0 | 0 | 0 | 75.0 | 93 | 43 | 39 | 19 | 53 | 9 | 12 |
| Brett Campbell |   | mr | 24 | 10.38 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 4 | 5 | 5 | 2 | 4 | 1 | 0 |
| Jorge Campillo |   | mr | 27 | 15.43 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.1 | 4 | 4 | 4 | 0 | 1 | 0 | 0 |
| Jose Capellan |   | mr | 25 | 4.40 | 4 | 2 | 0 | 61 | 0 | 0 | 0 | 71.2 | 65 | 37 | 35 | 31 | 58 | 11 | 2 |
| Matt Capps | MUL | mr | 22 | 3.79 | 9 | 1 | 1 | 85 | 0 | 0 | 0 | 80.2 | 81 | 37 | 34 | 12 | 56 | 12 | 9 |
| Chris Capuano* | BT | sp | 27 | 4.03 | 11 | 12 | 0 | 34 | 34 | 3 | 2 | 221.1 | 229 | 108 | 99 | 47 | 174 | 29 | 16 |
| Fausto Carmona | GEO | mr | 22 | 5.42 | 1 | 10 | 0 | 38 | 7 | 0 | 0 | 74.2 | 88 | 46 | 45 | 31 | 58 | 9 | 9 |
| Chris Carpenter | CRH | sp | 31 | 3.09 | 15 | 8 | 0 | 32 | 32 | 5 | 3 | 221.2 | 194 | 81 | 76 | 43 | 184 | 21 | 17 |
| Giovanni Carrara |   | mr | 38 | 4.55 | 0 | 1 | 1 | 25 | 0 | 0 | 0 | 27.2 | 27 | 14 | 14 | 7 | 25 | 5 | 3 |
| Hector Carrasco | LON | mr | 36 | 3.41 | 7 | 3 | 1 | 56 | 3 | 0 | 0 | 100.1 | 93 | 42 | 38 | 27 | 72 | 10 | 13 |
| Lance Carter |   | mr | 31 | 8.49 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 11.2 | 17 | 11 | 11 | 8 | 5 | 1 | 1 |
| Santiago Casilla |   | mr | 26 | 11.57 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 2 | 3 | 3 | 2 | 2 | 0 | 1 |
| Scott Cassidy |   | mr | 30 | 2.53 | 6 | 4 | 0 | 42 | 0 | 0 | 0 | 42.2 | 39 | 18 | 12 | 19 | 49 | 8 | 2 |
| Fabio Castro* |   | mr | 21 | 2.27 | 0 | 1 | 1 | 20 | 0 | 0 | 0 | 31.2 | 18 | 9 | 8 | 13 | 18 | 1 | 6 |
| Gustavo Chacin* |   | sp | 25 | 5.05 | 9 | 4 | 0 | 17 | 17 | 0 | 0 | 87.1 | 90 | 51 | 49 | 38 | 47 | 19 | 11 |
| Shawn Chacon |   | sp | 28 | 6.36 | 7 | 6 | 0 | 26 | 20 | 0 | 0 | 109.0 | 124 | 86 | 77 | 63 | 62 | 23 | 9 |
| Bruce Chen* |   | mr | 29 | 6.93 | 0 | 7 | 0 | 40 | 12 | 0 | 0 | 98.2 | 137 | 81 | 76 | 35 | 70 | 28 | 6 |
| Travis Chick |   | mr | 22 | 12.60 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5.0 | 7 | 7 | 7 | 10 | 2 | 0 | 1 |
| Jason Childers |   | mr | 31 | 4.70 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 7.2 | 12 | 6 | 4 | 4 | 5 | 1 | 2 |
| Randy Choate* |   | mr | 30 | 3.94 | 0 | 1 | 0 | 30 | 0 | 0 | 0 | 16.0 | 21 | 9 | 7 | 3 | 12 | 0 | 2 |
| Vinnie Chulk |   | mr | 27 | 5.24 | 1 | 3 | 0 | 48 | 0 | 0 | 0 | 46.1 | 46 | 29 | 27 | 20 | 43 | 6 | 2 |
| Brandon Claussen* |   | sp | 27 | 6.19 | 3 | 8 | 0 | 14 | 14 | 0 | 0 | 77.0 | 93 | 56 | 53 | 28 | 57 | 14 | 3 |
| Roger Clemens | ROK | sp | 43 | 2.30 | 7 | 6 | 0 | 19 | 19 | 0 | 0 | 113.1 | 89 | 34 | 29 | 29 | 102 | 7 | 11 |
| Matt Clement |   | sp | 31 | 6.61 | 5 | 5 | 0 | 12 | 12 | 0 | 0 | 65.1 | 77 | 50 | 48 | 38 | 43 | 8 | 6 |
| Todd Coffey |   | mr | 25 | 3.58 | 6 | 7 | 8 | 81 | 0 | 0 | 0 | 78.0 | 85 | 34 | 31 | 27 | 60 | 7 | 9 |
| Jesus Colome |   | mr | 28 | 27.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 |
| Bartolo Colon |   | sp | 33 | 5.11 | 1 | 5 | 0 | 10 | 10 | 1 | 1 | 56.1 | 71 | 39 | 32 | 11 | 31 | 11 | 3 |
| Roman Colon |   | mr | 26 | 4.89 | 2 | 0 | 1 | 20 | 1 | 0 | 0 | 38.2 | 46 | 21 | 21 | 14 | 25 | 6 | 3 |
| Clay Condrey |   | mr | 30 | 3.14 | 2 | 2 | 0 | 21 | 0 | 0 | 0 | 28.2 | 35 | 11 | 10 | 9 | 16 | 3 | 6 |
| Jose Contreras | GEO | sp | 34 | 4.27 | 13 | 9 | 0 | 30 | 30 | 1 | 1 | 196.0 | 194 | 101 | 93 | 55 | 134 | 20 | 12 |
| Aaron Cook | MAD | sp | 27 | 4.23 | 9 | 15 | 0 | 32 | 32 | 0 | 0 | 212.2 | 242 | 107 | 100 | 55 | 92 | 17 | 28 |
| Roy Corcoran |   | mr | 26 | 11.12 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 5.2 | 12 | 8 | 7 | 4 | 6 | 1 | 0 |
| Tim Corcoran |   | sp | 28 | 4.38 | 5 | 9 | 0 | 21 | 16 | 0 | 0 | 90.1 | 92 | 48 | 44 | 48 | 59 | 10 | 12 |
| Chad Cordero |   | cl | 24 | 3.19 | 7 | 4 | 29 | 68 | 0 | 0 | 0 | 73.1 | 59 | 27 | 26 | 22 | 69 | 13 | 1 |
| Francisco Cordero | CRH | cl | 31 | 3.70 | 10 | 5 | 22 | 77 | 0 | 0 | 0 | 75.1 | 69 | 32 | 31 | 32 | 84 | 7 | 7 |
| Bryan Corey |   | mr | 32 | 3.69 | 2 | 1 | 0 | 32 | 0 | 0 | 0 | 39.0 | 35 | 16 | 16 | 15 | 28 | 1 | 2 |
| Lance Cormier |   | mr | 25 | 4.89 | 4 | 5 | 0 | 29 | 9 | 0 | 0 | 73.2 | 90 | 44 | 40 | 39 | 43 | 8 | 13 |
| Rheal Cormier* |   | mr | 39 | 2.44 | 2 | 3 | 0 | 64 | 0 | 0 | 0 | 48.0 | 48 | 13 | 13 | 17 | 19 | 5 | 6 |
| Manuel Corpas |   | mr | 23 | 3.62 | 1 | 2 | 0 | 35 | 0 | 0 | 0 | 32.1 | 36 | 13 | 13 | 8 | 27 | 3 | 4 |
| Kevin Correia | MUL | mr | 25 | 3.49 | 2 | 0 | 0 | 48 | 0 | 0 | 0 | 69.2 | 64 | 27 | 27 | 22 | 57 | 5 | 1 |
| David Cortes |   | mr | 32 | 4.30 | 3 | 1 | 0 | 30 | 0 | 0 | 0 | 29.1 | 35 | 14 | 14 | 6 | 14 | 3 | 4 |
| Neal Cotts* |   | mr | 26 | 5.17 | 1 | 2 | 1 | 70 | 0 | 0 | 0 | 54.0 | 64 | 33 | 31 | 24 | 43 | 12 | 3 |
| Jesse Crain | GEO | mr | 24 | 3.52 | 4 | 5 | 1 | 68 | 0 | 0 | 0 | 76.2 | 79 | 31 | 30 | 18 | 60 | 6 | 3 |
| Francisco Cruceta |   | mr | 24 | 10.80 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 6.2 | 10 | 8 | 8 | 6 | 2 | 2 | 1 |
| Juan Cruz | TON | mr | 27 | 4.18 | 5 | 6 | 0 | 31 | 15 | 0 | 0 | 94.2 | 80 | 45 | 44 | 47 | 88 | 7 | 6 |
| Casey Daigle |   | mr | 25 | 3.65 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 12.1 | 14 | 5 | 5 | 6 | 7 | 1 | 5 |
| Kyle Davies |   | sp | 22 | 8.38 | 3 | 7 | 0 | 14 | 14 | 1 | 0 | 63.1 | 90 | 60 | 59 | 33 | 51 | 14 | 5 |
| Doug Davis* |   | sp | 30 | 4.91 | 11 | 11 | 0 | 34 | 34 | 1 | 1 | 203.1 | 206 | 118 | 111 | 102 | 159 | 19 | 21 |
| Jason Davis |   | mr | 26 | 3.74 | 3 | 2 | 1 | 39 | 0 | 0 | 0 | 55.1 | 67 | 28 | 23 | 14 | 37 | 1 | 4 |
| Zach Day |   | sp | 28 | 6.75 | 2 | 5 | 0 | 8 | 8 | 0 | 0 | 40.0 | 51 | 32 | 30 | 21 | 19 | 5 | 4 |
| Jorge De La Rosa* |   | mr | 25 | 6.49 | 5 | 6 | 0 | 28 | 13 | 0 | 0 | 79.0 | 81 | 59 | 57 | 54 | 67 | 14 | 9 |
| Mike DeJean |   | mr | 35 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1.2 | 1 | 0 | 0 | 2 | 0 | 0 | 0 |
| Manny Delcarmen |   | mr | 24 | 5.06 | 2 | 0 | 0 | 50 | 0 | 0 | 0 | 53.1 | 68 | 32 | 30 | 17 | 45 | 2 | 4 |
| Chris Demaria |   | mr | 25 | 5.93 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 13.2 | 10 | 11 | 9 | 9 | 11 | 4 | 0 |
| Ryan Dempster | CRH | cl | 29 | 4.80 | 1 | 9 | 24 | 74 | 0 | 0 | 0 | 75.0 | 77 | 47 | 40 | 36 | 67 | 5 | 6 |
| Elmer Dessens |   | mr | 35 | 4.56 | 5 | 8 | 2 | 62 | 0 | 0 | 0 | 77.0 | 86 | 43 | 39 | 22 | 52 | 8 | 8 |
| Joey Devine |   | mr | 22 | 9.95 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 6.1 | 8 | 7 | 7 | 9 | 10 | 1 | 1 |
| Jose Diaz |   | mr | 22 | 10.80 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.2 | 10 | 8 | 8 | 8 | 3 | 2 | 1 |
| R.A. Dickey | OTR | sp | 31 | 18.90 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 3.1 | 8 | 7 | 7 | 1 | 1 | 6 | 0 |
| Lenny DiNardo* |   | mr | 26 | 7.85 | 1 | 2 | 0 | 13 | 6 | 0 | 0 | 39.0 | 61 | 35 | 34 | 20 | 17 | 6 | 9 |
| Scott Dohmann |   | mr | 28 | 7.08 | 2 | 4 | 1 | 48 | 0 | 0 | 0 | 48.1 | 59 | 39 | 38 | 33 | 44 | 9 | 6 |
| Brendan Donnelly | CRH | mr | 34 | 3.94 | 6 | 0 | 0 | 62 | 0 | 0 | 0 | 64.0 | 58 | 32 | 28 | 28 | 53 | 8 | 6 |
| Octavio Dotel |   | mr | 32 | 10.80 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 10.0 | 18 | 13 | 12 | 11 | 7 | 2 | 1 |
| Scott Downs* | EDG | mr | 30 | 4.09 | 6 | 2 | 1 | 59 | 5 | 0 | 0 | 77.0 | 73 | 38 | 35 | 30 | 61 | 9 | 9 |
| Ryan Drese |   | sp | 30 | 5.19 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 8.2 | 9 | 8 | 5 | 8 | 5 | 0 | 0 |
| Eric DuBose* |   | mr | 30 | 9.64 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.2 | 10 | 5 | 5 | 3 | 2 | 2 | 4 |
| Justin Duchscherer | COP | mr | 28 | 2.91 | 2 | 1 | 9 | 53 | 0 | 0 | 0 | 55.2 | 52 | 18 | 18 | 9 | 51 | 4 | 3 |
| Brandon Duckworth |   | sp | 30 | 6.11 | 1 | 5 | 0 | 10 | 8 | 0 | 0 | 45.2 | 62 | 36 | 31 | 24 | 27 | 3 | 5 |
| Zach Duke* |   | sp | 23 | 4.47 | 10 | 15 | 0 | 34 | 34 | 2 | 1 | 215.1 | 255 | 116 | 107 | 68 | 117 | 17 | 27 |
| Scott Dunn |   | mr | 28 | 11.74 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 7.2 | 17 | 10 | 10 | 4 | 4 | 2 | 1 |
| Chad Durbin |   | mr | 28 | 1.50 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 6.0 | 6 | 1 | 1 | 0 | 3 | 1 | 0 |
| Adam Eaton |   | sp | 28 | 5.12 | 7 | 4 | 0 | 13 | 13 | 0 | 0 | 65.0 | 78 | 38 | 37 | 24 | 43 | 11 | 4 |
| Joey Eischen* |   | mr | 36 | 8.59 | 0 | 1 | 0 | 22 | 0 | 0 | 0 | 14.2 | 18 | 18 | 14 | 19 | 18 | 2 | 0 |
| Scott Elarton |   | sp | 30 | 5.34 | 4 | 9 | 0 | 20 | 20 | 0 | 0 | 114.2 | 117 | 73 | 68 | 52 | 49 | 26 | 10 |
| Alan Embree* | LON | mr | 36 | 3.27 | 4 | 3 | 0 | 73 | 0 | 0 | 0 | 52.1 | 50 | 21 | 19 | 15 | 53 | 4 | 2 |
| Scott Erickson |   | mr | 38 | 7.94 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 11.1 | 13 | 12 | 10 | 7 | 2 | 2 | 2 |
| Kelvim Escobar | COP | sp | 30 | 3.61 | 11 | 14 | 0 | 30 | 30 | 1 | 0 | 189.1 | 192 | 93 | 76 | 50 | 147 | 17 | 15 |
| Shawn Estes* |   | sp | 33 | 4.50 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 6.0 | 5 | 3 | 3 | 3 | 4 | 0 | 1 |
| Seth Etherton |   | sp | 29 | 9.39 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 7.2 | 10 | 9 | 8 | 6 | 4 | 3 | 0 |
| Dana Eveland* |   | sp | 22 | 8.13 | 0 | 3 | 0 | 9 | 5 | 0 | 0 | 27.2 | 39 | 25 | 25 | 16 | 32 | 4 | 1 |
| Scott Eyre* |   | mr | 34 | 3.38 | 1 | 3 | 0 | 74 | 0 | 0 | 0 | 61.1 | 61 | 25 | 23 | 30 | 73 | 11 | 4 |
| Willie Eyre |   | mr | 27 | 5.31 | 1 | 0 | 0 | 42 | 0 | 0 | 0 | 59.1 | 75 | 36 | 35 | 22 | 26 | 8 | 5 |
| Brian Falkenborg |   | mr | 28 | 2.84 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 6.1 | 5 | 2 | 2 | 0 | 5 | 0 | 0 |
| Kyle Farnsworth | BON | mr | 30 | 4.36 | 3 | 6 | 6 | 72 | 0 | 0 | 0 | 66.0 | 62 | 34 | 32 | 28 | 75 | 8 | 1 |
| Jeff Fassero* |   | mr | 43 | 7.80 | 1 | 1 | 0 | 10 | 1 | 0 | 0 | 15.0 | 23 | 13 | 13 | 8 | 7 | 4 | 2 |
| Ryan Feierabend* |   | sp | 20 | 3.71 | 0 | 1 | 0 | 4 | 2 | 0 | 0 | 17.0 | 15 | 7 | 7 | 7 | 11 | 3 | 2 |
| Scott Feldman | MID | mr | 23 | 3.92 | 0 | 2 | 0 | 36 | 0 | 0 | 0 | 41.1 | 42 | 19 | 18 | 10 | 30 | 4 | 3 |
| Pedro Feliciano* | MAD | mr | 29 | 2.09 | 7 | 2 | 0 | 64 | 0 | 0 | 0 | 60.1 | 56 | 15 | 14 | 20 | 54 | 4 | 6 |
| Jared Fernandez |   | mr | 34 | 9.95 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.1 | 11 | 7 | 7 | 1 | 1 | 2 | 0 |
| Nate Field |   | mr | 30 | 4.00 | 1 | 1 | 0 | 14 | 0 | 0 | 0 | 9.0 | 9 | 4 | 4 | 5 | 14 | 2 | 1 |
| Randy Flores* |   | mr | 30 | 5.62 | 1 | 1 | 0 | 65 | 0 | 0 | 0 | 41.2 | 49 | 29 | 26 | 22 | 40 | 5 | 3 |
| Ron Flores* |   | mr | 26 | 3.34 | 1 | 2 | 1 | 25 | 0 | 0 | 0 | 29.2 | 28 | 11 | 11 | 10 | 20 | 3 | 6 |
| Gavin Floyd | TON | sp | 23 | 7.29 | 4 | 3 | 0 | 11 | 11 | 1 | 1 | 54.1 | 70 | 48 | 44 | 32 | 34 | 14 | 6 |
| Josh Fogg |   | sp | 29 | 5.49 | 11 | 9 | 0 | 31 | 31 | 1 | 1 | 172.0 | 206 | 115 | 105 | 60 | 93 | 24 | 17 |
| Bartolome Fortunato |   | mr | 31 | 27.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 7 | 9 | 9 | 2 | 0 | 2 | 1 |
| Casey Fossum* |   | sp | 28 | 5.33 | 6 | 6 | 0 | 25 | 25 | 0 | 0 | 130.0 | 136 | 89 | 77 | 63 | 88 | 18 | 10 |
| Keith Foulke |   | mr | 33 | 4.35 | 3 | 1 | 0 | 44 | 0 | 0 | 0 | 49.2 | 52 | 24 | 24 | 7 | 36 | 9 | 3 |
| Jeff Francis* | MAD | sp | 25 | 4.16 | 13 | 11 | 0 | 32 | 32 | 1 | 1 | 199.0 | 187 | 101 | 92 | 69 | 117 | 18 | 24 |
| Frank Francisco |   | mr | 26 | 4.91 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 7.1 | 8 | 4 | 4 | 2 | 6 | 2 | 0 |
| Ryan Franklin |   | mr | 33 | 4.54 | 6 | 7 | 0 | 66 | 0 | 0 | 0 | 77.1 | 86 | 42 | 39 | 33 | 43 | 13 | 9 |
| Wayne Franklin* |   | mr | 32 | 7.04 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 7.2 | 8 | 6 | 6 | 6 | 3 | 2 | 2 |
| Jason Frasor | MID | mr | 28 | 4.32 | 3 | 2 | 0 | 51 | 0 | 0 | 0 | 50.0 | 47 | 24 | 24 | 17 | 51 | 8 | 1 |
| Emiliano Fruto |   | mr | 22 | 5.50 | 2 | 2 | 1 | 23 | 0 | 0 | 0 | 36.0 | 34 | 24 | 22 | 24 | 34 | 4 | 3 |
| Brian Fuentes* | CCL | cl | 30 | 3.44 | 3 | 4 | 30 | 66 | 0 | 0 | 0 | 65.1 | 50 | 25 | 25 | 26 | 73 | 8 | 4 |
| Jeff Fulchino |   | mr | 26 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Aaron Fultz* | MAD | mr | 32 | 4.54 | 3 | 1 | 0 | 66 | 1 | 0 | 0 | 71.1 | 80 | 39 | 36 | 28 | 62 | 7 | 6 |
| Kason Gabbard* |   | sp | 24 | 3.51 | 1 | 3 | 0 | 7 | 4 | 0 | 0 | 25.2 | 24 | 11 | 10 | 16 | 15 | 0 | 6 |
| Eric Gagne |   | cl | 30 | 0.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 2.0 | 0 | 0 | 0 | 1 | 3 | 0 | 0 |
| Mike Gallo* |   | mr | 28 | 6.06 | 1 | 2 | 0 | 23 | 0 | 0 | 0 | 16.1 | 28 | 11 | 11 | 7 | 7 | 3 | 4 |
| Freddy Garcia | EDG | sp | 30 | 4.53 | 17 | 9 | 0 | 33 | 33 | 1 | 0 | 216.1 | 228 | 116 | 109 | 48 | 135 | 32 | 14 |
| Jose Garcia |   | mr | 21 | 4.91 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 11.0 | 10 | 6 | 6 | 5 | 8 | 1 | 0 |
| Jon Garland | COP | sp | 26 | 4.51 | 18 | 7 | 0 | 33 | 32 | 1 | 1 | 211.1 | 247 | 112 | 106 | 41 | 112 | 26 | 23 |
| Matt Garza | GEO | sp | 22 | 5.76 | 3 | 6 | 0 | 10 | 9 | 0 | 0 | 50.0 | 62 | 33 | 32 | 23 | 38 | 6 | 3 |
| Chad Gaudin |   | mr | 23 | 3.09 | 4 | 2 | 2 | 55 | 0 | 0 | 0 | 64.0 | 51 | 24 | 22 | 42 | 36 | 3 | 6 |
| Geoff Geary |   | mr | 29 | 2.96 | 7 | 1 | 1 | 81 | 0 | 0 | 0 | 91.1 | 103 | 34 | 30 | 20 | 60 | 6 | 15 |
| Franklyn German |   | mr | 26 | 3.00 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 12.0 | 7 | 4 | 4 | 14 | 6 | 1 | 0 |
| Justin Germano |   | sp | 23 | 5.40 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 6.2 | 8 | 4 | 4 | 3 | 8 | 1 | 2 |
| Tom Glavine* | WIZ | sp | 40 | 3.82 | 15 | 7 | 0 | 32 | 32 | 0 | 0 | 198.0 | 202 | 94 | 84 | 62 | 131 | 22 | 18 |
| Jimmy Gobble* |   | mr | 24 | 5.14 | 4 | 6 | 2 | 60 | 6 | 0 | 0 | 84.0 | 95 | 51 | 48 | 29 | 80 | 12 | 8 |
| Edgar Gonzalez |   | mr | 23 | 4.22 | 3 | 4 | 0 | 11 | 5 | 0 | 0 | 42.2 | 45 | 20 | 20 | 9 | 28 | 7 | 4 |
| Enrique Gonzalez | CCL | sp | 23 | 5.67 | 3 | 7 | 0 | 22 | 18 | 0 | 0 | 106.1 | 114 | 71 | 67 | 34 | 66 | 14 | 6 |
| Geremi Gonzalez |   | mr | 31 | 5.79 | 4 | 2 | 0 | 24 | 4 | 0 | 0 | 56.0 | 71 | 43 | 36 | 23 | 44 | 10 | 1 |
| Mike Gonzalez* | BT | cl | 28 | 2.17 | 3 | 4 | 24 | 54 | 0 | 0 | 0 | 54.0 | 42 | 13 | 13 | 31 | 64 | 1 | 2 |
| Tom Gordon | BT | cl | 38 | 3.34 | 3 | 4 | 34 | 59 | 0 | 0 | 0 | 59.1 | 53 | 23 | 22 | 22 | 68 | 9 | 3 |
| Tom Gorzelanny* | LON | sp | 23 | 3.79 | 2 | 5 | 0 | 11 | 11 | 0 | 0 | 61.2 | 50 | 29 | 26 | 31 | 40 | 3 | 6 |
| Mike Gosling* |   | mr | 25 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 1 | 2 | 2 | 1 | 1 | 1 | 0 |
| John Grabow* |   | mr | 27 | 4.13 | 4 | 2 | 0 | 72 | 0 | 0 | 0 | 69.2 | 68 | 34 | 32 | 30 | 66 | 7 | 5 |
| Danny Graves |   | mr | 32 | 5.79 | 2 | 1 | 0 | 13 | 0 | 0 | 0 | 14.0 | 18 | 12 | 9 | 5 | 3 | 3 | 2 |
| Sean Green |   | mr | 27 | 4.50 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 32.0 | 34 | 16 | 16 | 13 | 15 | 2 | 5 |
| Kevin Gregg |   | mr | 28 | 4.14 | 3 | 4 | 0 | 32 | 3 | 0 | 0 | 78.1 | 88 | 41 | 36 | 21 | 71 | 10 | 4 |
| Zack Greinke | COP | mr | 22 | 4.26 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 6.1 | 7 | 3 | 3 | 3 | 5 | 1 | 0 |
| Jason Grilli |   | mr | 29 | 4.21 | 2 | 3 | 0 | 51 | 0 | 0 | 0 | 62.0 | 61 | 31 | 29 | 25 | 31 | 6 | 5 |
| Jason Grimsley |   | mr | 38 | 4.88 | 1 | 2 | 0 | 19 | 0 | 0 | 0 | 27.2 | 30 | 15 | 15 | 8 | 10 | 4 | 5 |
| Kevin Gryboski |   | mr | 32 | 14.29 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 5.2 | 14 | 11 | 9 | 2 | 4 | 3 | 0 |
| Eddie Guardado* |   | cl | 35 | 3.89 | 1 | 3 | 13 | 43 | 0 | 0 | 0 | 37.0 | 44 | 19 | 16 | 13 | 39 | 10 | 3 |
| Matt Guerrier |   | mr | 27 | 3.36 | 1 | 0 | 1 | 39 | 1 | 0 | 0 | 69.2 | 78 | 29 | 26 | 21 | 37 | 9 | 5 |
| Jeremy Guthrie |   | mr | 27 | 6.98 | 0 | 0 | 0 | 9 | 1 | 0 | 0 | 19.1 | 24 | 15 | 15 | 15 | 14 | 2 | 3 |
| Angel Guzman |   | sp | 24 | 7.39 | 0 | 6 | 0 | 15 | 10 | 0 | 0 | 56.0 | 68 | 48 | 46 | 37 | 60 | 9 | 3 |
| Charlie Haeger |   | mr | 22 | 3.44 | 1 | 1 | 1 | 7 | 1 | 0 | 0 | 18.1 | 12 | 10 | 7 | 13 | 19 | 0 | 2 |
| John Halama* |   | mr | 34 | 6.14 | 3 | 1 | 0 | 17 | 1 | 0 | 0 | 29.1 | 38 | 20 | 20 | 13 | 12 | 6 | 3 |
| Roy Halladay | ROK | sp | 29 | 3.19 | 16 | 5 | 0 | 32 | 32 | 4 | 0 | 220.0 | 208 | 82 | 78 | 34 | 132 | 19 | 23 |
| Brad Halsey* |   | mr | 25 | 4.67 | 5 | 4 | 0 | 52 | 7 | 0 | 0 | 94.1 | 108 | 53 | 49 | 46 | 53 | 11 | 11 |
| Cole Hamels* | WIZ | sp | 22 | 4.08 | 9 | 8 | 0 | 23 | 23 | 0 | 0 | 132.1 | 117 | 66 | 60 | 48 | 145 | 19 | 5 |
| Jason Hammel |   | sp | 23 | 7.77 | 0 | 6 | 0 | 9 | 9 | 0 | 0 | 44.0 | 61 | 38 | 38 | 21 | 32 | 7 | 3 |
| Chris Hammond* |   | mr | 40 | 6.91 | 1 | 1 | 0 | 29 | 0 | 0 | 0 | 28.2 | 36 | 23 | 22 | 5 | 23 | 5 | 3 |
| Justin Hampson* |   | mr | 26 | 7.50 | 1 | 0 | 0 | 5 | 1 | 0 | 0 | 12.0 | 19 | 10 | 10 | 5 | 9 | 3 | 1 |
| Tim Hamulack* |   | mr | 29 | 6.35 | 0 | 3 | 0 | 33 | 0 | 0 | 0 | 34.0 | 36 | 28 | 24 | 22 | 34 | 7 | 5 |
| Josh Hancock | MUL | mr | 28 | 4.09 | 3 | 3 | 1 | 62 | 0 | 0 | 0 | 77.0 | 70 | 37 | 35 | 23 | 50 | 9 | 10 |
| Devern Hansack |   | sp | 28 | 2.70 | 1 | 1 | 0 | 2 | 2 | 1 | 1 | 10.0 | 6 | 3 | 3 | 1 | 8 | 2 | 1 |
| Craig Hansen |   | mr | 22 | 6.63 | 2 | 2 | 0 | 38 | 0 | 0 | 0 | 38.0 | 46 | 32 | 28 | 15 | 30 | 5 | 4 |
| Aaron Harang | GEO | sp | 28 | 3.76 | 16 | 11 | 0 | 36 | 35 | 6 | 2 | 234.1 | 242 | 109 | 98 | 56 | 216 | 28 | 15 |
| Rich Harden | COP | sp | 24 | 4.24 | 4 | 0 | 0 | 9 | 9 | 0 | 0 | 46.2 | 31 | 22 | 22 | 26 | 49 | 5 | 3 |
| Dan Haren | LON | sp | 25 | 4.12 | 14 | 13 | 0 | 34 | 34 | 2 | 0 | 223.0 | 224 | 109 | 102 | 45 | 176 | 31 | 16 |
| Travis Harper |   | mr | 30 | 4.93 | 2 | 0 | 0 | 30 | 0 | 0 | 0 | 42.0 | 62 | 27 | 23 | 13 | 32 | 6 | 3 |
| Jeff Harris |   | mr | 31 | 5.40 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.1 | 3 | 2 | 2 | 0 | 1 | 0 | 1 |
| Chad Harville |   | mr | 29 | 5.93 | 0 | 2 | 1 | 32 | 0 | 0 | 0 | 41.0 | 44 | 27 | 27 | 22 | 30 | 5 | 4 |
| LaTroy Hawkins |   | mr | 33 | 4.48 | 3 | 2 | 0 | 60 | 0 | 0 | 0 | 60.1 | 73 | 30 | 30 | 15 | 27 | 4 | 4 |
| Aaron Heilman | WIZ | mr | 27 | 3.62 | 4 | 5 | 0 | 74 | 0 | 0 | 0 | 87.0 | 73 | 37 | 35 | 28 | 73 | 5 | 8 |
| Rick Helling |   | mr | 35 | 4.11 | 0 | 2 | 0 | 20 | 2 | 0 | 0 | 35.0 | 25 | 17 | 16 | 15 | 32 | 6 | 3 |
| Ben Hendrickson |   | sp | 25 | 12.00 | 0 | 2 | 0 | 4 | 3 | 0 | 0 | 12.0 | 21 | 17 | 16 | 9 | 8 | 0 | 0 |
| Mark Hendrickson* | MUL | sp | 32 | 4.21 | 6 | 15 | 0 | 31 | 25 | 1 | 1 | 164.2 | 173 | 87 | 77 | 62 | 99 | 17 | 15 |
| Sean Henn* |   | mr | 25 | 4.82 | 0 | 1 | 0 | 4 | 1 | 0 | 0 | 9.1 | 11 | 5 | 5 | 5 | 7 | 2 | 1 |
| Brad Hennessey |   | mr | 26 | 4.26 | 5 | 6 | 1 | 34 | 12 | 0 | 0 | 99.1 | 92 | 53 | 47 | 42 | 42 | 12 | 10 |
| Clay Hensley | WIZ | sp | 26 | 3.71 | 11 | 12 | 0 | 37 | 29 | 1 | 1 | 187.0 | 174 | 82 | 77 | 76 | 122 | 15 | 27 |
| Matt Herges |   | mr | 36 | 4.31 | 2 | 3 | 0 | 66 | 0 | 0 | 0 | 71.0 | 94 | 42 | 34 | 28 | 36 | 5 | 11 |
| Dustin Hermanson |   | mr | 33 | 4.05 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 6.2 | 6 | 3 | 3 | 1 | 5 | 2 | 1 |
| Felix Hernandez | ROK | sp | 20 | 4.52 | 12 | 14 | 0 | 31 | 31 | 2 | 1 | 191.0 | 195 | 105 | 96 | 60 | 176 | 23 | 18 |
| Livan Hernandez |   | sp | 31 | 4.83 | 13 | 13 | 0 | 34 | 34 | 0 | 0 | 216.0 | 246 | 125 | 116 | 78 | 128 | 29 | 12 |
| Orlando Hernandez | Pal | sp | 36 | 4.66 | 11 | 11 | 0 | 29 | 29 | 1 | 0 | 162.1 | 155 | 90 | 84 | 61 | 164 | 22 | 6 |
| Roberto Hernandez |   | mr | 41 | 3.11 | 0 | 3 | 2 | 68 | 0 | 0 | 0 | 63.2 | 61 | 32 | 22 | 32 | 48 | 5 | 4 |
| Runelvys Hernandez |   | sp | 28 | 6.48 | 6 | 10 | 0 | 21 | 21 | 1 | 1 | 109.2 | 145 | 87 | 79 | 48 | 50 | 22 | 13 |
| Rich Hill* | BT | sp | 26 | 4.17 | 6 | 7 | 0 | 17 | 16 | 2 | 1 | 99.1 | 83 | 51 | 46 | 39 | 90 | 16 | 5 |
| Shawn Hill |   | sp | 25 | 4.66 | 1 | 3 | 0 | 6 | 6 | 0 | 0 | 36.2 | 43 | 20 | 19 | 12 | 16 | 2 | 3 |
| Jason Hirsh |   | sp | 24 | 6.04 | 3 | 4 | 0 | 9 | 9 | 0 | 0 | 44.2 | 48 | 32 | 30 | 22 | 29 | 11 | 2 |
| James Hoey |   | mr | 23 | 10.24 | 0 | 1 | 0 | 12 | 0 | 0 | 0 | 9.2 | 14 | 11 | 11 | 5 | 6 | 1 | 1 |
| Trevor Hoffman | Pal | cl | 38 | 2.14 | 0 | 2 | 46 | 65 | 0 | 0 | 0 | 63.0 | 48 | 16 | 15 | 13 | 50 | 6 | 5 |
| Mike Holtz* |   | mr | 33 | 16.20 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1.2 | 3 | 3 | 3 | 4 | 2 | 0 | 0 |
| J.P. Howell* | MID | sp | 23 | 5.10 | 1 | 3 | 0 | 8 | 8 | 0 | 0 | 42.1 | 52 | 25 | 24 | 14 | 33 | 4 | 6 |
| Bob Howry | COP | mr | 32 | 3.17 | 4 | 5 | 5 | 84 | 0 | 0 | 0 | 76.2 | 70 | 28 | 27 | 17 | 71 | 8 | 3 |
| Jon Huber |   | mr | 24 | 1.08 | 2 | 1 | 0 | 16 | 0 | 0 | 0 | 16.2 | 10 | 3 | 2 | 6 | 11 | 0 | 2 |
| Luke Hudson | MID | sp | 29 | 5.12 | 7 | 6 | 0 | 26 | 15 | 0 | 0 | 102.0 | 109 | 62 | 58 | 38 | 64 | 7 | 17 |
| Tim Hudson | GEO | sp | 30 | 4.86 | 13 | 12 | 0 | 35 | 35 | 2 | 1 | 218.1 | 235 | 129 | 118 | 79 | 141 | 25 | 20 |
| Travis Hughes |   | mr | 28 | 6.35 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 11.1 | 13 | 8 | 8 | 6 | 4 | 2 | 2 |
| Philip Humber |   | mr | 23 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 |
| Jason Isringhausen | Pal | cl | 33 | 3.55 | 4 | 8 | 33 | 59 | 0 | 0 | 0 | 58.1 | 47 | 25 | 23 | 38 | 52 | 10 | 5 |
| Edwin Jackson |   | mr | 22 | 5.45 | 0 | 0 | 0 | 23 | 1 | 0 | 0 | 36.1 | 42 | 27 | 22 | 25 | 27 | 2 | 4 |
| Zach Jackson* |   | sp | 23 | 5.40 | 2 | 2 | 0 | 8 | 7 | 0 | 0 | 38.1 | 48 | 26 | 23 | 14 | 22 | 6 | 5 |
| Chuck James* | Pal | sp | 24 | 3.78 | 11 | 4 | 0 | 25 | 18 | 0 | 0 | 119.0 | 101 | 54 | 50 | 47 | 91 | 20 | 5 |
| Casey Janssen | OTR | sp | 24 | 5.07 | 6 | 10 | 0 | 19 | 17 | 0 | 0 | 94.0 | 103 | 58 | 53 | 21 | 44 | 12 | 7 |
| Kevin Jarvis |   | mr | 36 | 7.71 | 0 | 2 | 0 | 9 | 4 | 0 | 0 | 28.0 | 40 | 27 | 24 | 11 | 13 | 3 | 3 |
| Bobby Jenks | OTR | cl | 25 | 4.00 | 3 | 4 | 41 | 67 | 0 | 0 | 0 | 69.2 | 66 | 32 | 31 | 31 | 80 | 5 | 8 |
| Jason Jennings | CCL | sp | 27 | 3.78 | 9 | 13 | 0 | 32 | 32 | 3 | 2 | 212.0 | 206 | 94 | 89 | 85 | 142 | 17 | 21 |
| Cesar Jimenez* |   | mr | 21 | 14.73 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 7.1 | 13 | 12 | 12 | 4 | 3 | 4 | 1 |
| Ubaldo Jimenez |   | sp | 22 | 3.52 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 7.2 | 5 | 4 | 3 | 3 | 3 | 1 | 0 |
| Jason Johnson |   | sp | 32 | 6.10 | 3 | 12 | 0 | 24 | 20 | 0 | 0 | 115.0 | 160 | 86 | 78 | 35 | 54 | 14 | 20 |
| Jim Johnson |   | sp | 23 | 24.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 3.0 | 9 | 8 | 8 | 3 | 0 | 1 | 0 |
| Josh Johnson | LON | sp | 22 | 3.10 | 12 | 7 | 0 | 31 | 24 | 0 | 0 | 157.0 | 136 | 63 | 54 | 68 | 133 | 14 | 14 |
| Randy Johnson* | ROK | sp | 42 | 5.00 | 17 | 11 | 0 | 33 | 33 | 2 | 0 | 205.0 | 194 | 125 | 114 | 60 | 172 | 28 | 12 |
| Tyler Johnson* |   | mr | 25 | 4.95 | 2 | 4 | 0 | 56 | 0 | 0 | 0 | 36.1 | 33 | 21 | 20 | 23 | 37 | 5 | 4 |
| Greg Jones |   | mr | 29 | 6.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.0 | 8 | 5 | 4 | 2 | 1 | 1 | 1 |
| Todd Jones | MUL | cl | 38 | 3.94 | 2 | 6 | 37 | 62 | 0 | 0 | 0 | 64.0 | 70 | 31 | 28 | 11 | 28 | 4 | 8 |
| Jorge Julio |   | cl | 27 | 4.23 | 2 | 4 | 16 | 62 | 0 | 0 | 0 | 66.0 | 52 | 35 | 31 | 35 | 88 | 10 | 2 |
| Steve Karsay |   | mr | 34 | 5.79 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 9.1 | 13 | 6 | 6 | 3 | 5 | 4 | 2 |
| Jeff Karstens | BON | sp | 23 | 3.80 | 2 | 1 | 0 | 8 | 6 | 0 | 0 | 42.2 | 40 | 20 | 18 | 11 | 16 | 6 | 1 |
| Scott Kazmir* | GEO | sp | 22 | 3.24 | 10 | 8 | 0 | 24 | 24 | 1 | 1 | 144.2 | 132 | 59 | 52 | 52 | 163 | 15 | 7 |
| Randy Keisler* |   | mr | 30 | 4.50 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 10.0 | 14 | 5 | 5 | 2 | 5 | 3 | 3 |
| Joe Kennedy* |   | mr | 27 | 2.31 | 4 | 1 | 1 | 39 | 0 | 0 | 0 | 35.0 | 34 | 10 | 9 | 13 | 29 | 1 | 6 |
| Logan Kensing |   | mr | 23 | 4.54 | 1 | 3 | 1 | 37 | 0 | 0 | 0 | 37.2 | 30 | 19 | 19 | 19 | 45 | 6 | 1 |
| Bobby Keppel |   | sp | 24 | 5.50 | 0 | 4 | 0 | 8 | 6 | 0 | 0 | 34.1 | 45 | 21 | 21 | 15 | 20 | 6 | 4 |
| Byung-Hyun Kim |   | sp | 27 | 5.57 | 8 | 12 | 0 | 27 | 27 | 0 | 0 | 155.0 | 179 | 103 | 96 | 61 | 129 | 18 | 17 |
| Sun-Woo Kim |   | mr | 28 | 12.51 | 0 | 1 | 0 | 8 | 1 | 0 | 0 | 13.2 | 24 | 19 | 19 | 8 | 8 | 5 | 0 |
| Ray King* |   | mr | 32 | 4.43 | 1 | 4 | 1 | 67 | 0 | 0 | 0 | 44.2 | 56 | 26 | 22 | 20 | 23 | 6 | 12 |
| Josh Kinney |   | mr | 27 | 3.24 | 0 | 0 | 0 | 21 | 0 | 0 | 0 | 25.0 | 17 | 9 | 9 | 8 | 22 | 3 | 3 |
| Steve Kline* |   | mr | 33 | 3.66 | 4 | 3 | 1 | 72 | 0 | 0 | 0 | 51.2 | 53 | 24 | 21 | 26 | 33 | 3 | 7 |
| Dan Kolb |   | mr | 31 | 4.84 | 2 | 2 | 1 | 53 | 0 | 0 | 0 | 48.1 | 53 | 28 | 26 | 20 | 26 | 4 | 8 |
| Shane Komine |   | sp | 25 | 5.00 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 9.0 | 10 | 5 | 5 | 8 | 1 | 3 | 1 |
| Mike Koplove |   | mr | 29 | 3.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 5 | 1 | 1 | 2 | 1 | 0 | 0 |
| John Koronka* |   | sp | 25 | 5.69 | 7 | 7 | 0 | 23 | 23 | 0 | 0 | 125.0 | 145 | 80 | 79 | 47 | 61 | 17 | 10 |
| Hong-Chih Kuo* | Pal | mr | 24 | 4.22 | 1 | 5 | 0 | 28 | 5 | 0 | 0 | 59.2 | 54 | 30 | 28 | 33 | 71 | 3 | 7 |
| John Lackey | COP | sp | 27 | 3.56 | 13 | 11 | 0 | 33 | 33 | 3 | 2 | 217.2 | 203 | 98 | 86 | 72 | 190 | 14 | 18 |
| Juan Lara* |   | mr | 25 | 1.80 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 5.0 | 4 | 2 | 1 | 1 | 2 | 0 | 2 |
| Brandon League | CRH | mr | 23 | 2.53 | 1 | 2 | 1 | 33 | 0 | 0 | 0 | 42.2 | 34 | 17 | 12 | 9 | 29 | 3 | 7 |
| Wilfredo Ledezma* |   | mr | 25 | 3.58 | 3 | 3 | 0 | 24 | 7 | 0 | 0 | 60.1 | 60 | 28 | 24 | 23 | 39 | 5 | 2 |
| Cliff Lee* | MID | sp | 27 | 4.40 | 14 | 11 | 0 | 33 | 33 | 1 | 0 | 200.2 | 224 | 114 | 98 | 58 | 129 | 29 | 14 |
| Justin Lehr |   | mr | 28 | 8.62 | 2 | 1 | 0 | 16 | 0 | 0 | 0 | 15.2 | 24 | 16 | 15 | 7 | 12 | 2 | 4 |
| Anthony Lerew |   | mr | 23 | 22.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 5 | 5 | 5 | 3 | 1 | 0 | 0 |
| Jon Lester* | EDG | sp | 22 | 4.76 | 7 | 2 | 0 | 15 | 15 | 0 | 0 | 81.1 | 91 | 43 | 43 | 43 | 60 | 7 | 8 |
| Colby Lewis |   | mr | 26 | 3.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 8 | 1 | 1 | 1 | 5 | 1 | 0 |
| Brad Lidge | Pal | cl | 29 | 5.28 | 1 | 5 | 32 | 78 | 0 | 0 | 0 | 75.0 | 69 | 47 | 44 | 36 | 104 | 10 | 2 |
| Cory Lidle |   | sp | 34 | 4.85 | 12 | 10 | 0 | 31 | 30 | 0 | 0 | 170.2 | 181 | 100 | 92 | 58 | 130 | 30 | 15 |
| Jon Lieber |   | sp | 36 | 4.93 | 9 | 11 | 0 | 27 | 27 | 2 | 1 | 168.0 | 196 | 100 | 92 | 24 | 100 | 27 | 12 |
| Ted Lilly* | OTR | sp | 30 | 4.31 | 15 | 13 | 0 | 32 | 32 | 0 | 0 | 181.2 | 179 | 98 | 87 | 81 | 160 | 28 | 13 |
| Jose Lima |   | sp | 33 | 9.87 | 0 | 4 | 0 | 4 | 4 | 0 | 0 | 17.1 | 25 | 22 | 19 | 10 | 12 | 3 | 1 |
| Scott Linebrink |   | mr | 29 | 3.57 | 7 | 4 | 2 | 73 | 0 | 0 | 0 | 75.2 | 70 | 31 | 30 | 22 | 68 | 9 | 3 |
| Francisco Liriano* | ROK | sp | 22 | 2.16 | 12 | 3 | 1 | 28 | 16 | 0 | 0 | 121.0 | 89 | 31 | 29 | 32 | 144 | 9 | 17 |
| Wes Littleton |   | mr | 23 | 1.73 | 2 | 1 | 1 | 33 | 0 | 0 | 0 | 36.1 | 23 | 7 | 7 | 13 | 17 | 2 | 9 |
| Bobby Livingston* |   | mr | 23 | 18.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5.0 | 9 | 10 | 10 | 6 | 3 | 2 | 0 |
| Esteban Loaiza |   | sp | 34 | 4.89 | 11 | 9 | 0 | 26 | 26 | 2 | 1 | 154.2 | 179 | 92 | 84 | 40 | 97 | 17 | 12 |
| Kameron Loe |   | sp | 24 | 5.86 | 3 | 6 | 0 | 15 | 15 | 1 | 1 | 78.1 | 105 | 54 | 51 | 22 | 34 | 10 | 7 |
| Adam Loewen* | MID | sp | 22 | 5.37 | 6 | 6 | 0 | 22 | 19 | 0 | 0 | 112.1 | 111 | 72 | 67 | 62 | 98 | 8 | 9 |
| Boone Logan* |   | mr | 21 | 8.31 | 0 | 0 | 1 | 21 | 0 | 0 | 0 | 17.1 | 21 | 18 | 16 | 15 | 15 | 2 | 2 |
| Kyle Lohse | MID | sp | 27 | 5.83 | 5 | 10 | 0 | 34 | 19 | 0 | 0 | 126.2 | 150 | 83 | 82 | 44 | 97 | 15 | 10 |
| Braden Looper | MAD | mr | 31 | 3.56 | 9 | 3 | 0 | 69 | 0 | 0 | 0 | 73.1 | 76 | 30 | 29 | 20 | 41 | 3 | 9 |
| Javier Lopez* |   | mr | 28 | 2.70 | 1 | 0 | 1 | 27 | 0 | 0 | 0 | 16.2 | 13 | 10 | 5 | 10 | 11 | 1 | 5 |
| Rodrigo Lopez |   | sp | 30 | 5.90 | 9 | 18 | 0 | 36 | 29 | 0 | 0 | 189.0 | 234 | 129 | 124 | 59 | 136 | 32 | 9 |
| Derek Lowe | BON | sp | 33 | 3.63 | 16 | 8 | 0 | 35 | 34 | 1 | 0 | 218.0 | 221 | 97 | 88 | 55 | 123 | 14 | 29 |
| Mark Lowe |   | mr | 23 | 1.93 | 1 | 0 | 0 | 15 | 0 | 0 | 0 | 18.2 | 12 | 4 | 4 | 9 | 20 | 1 | 3 |
| Noah Lowry* |   | sp | 25 | 4.74 | 7 | 10 | 0 | 27 | 27 | 1 | 1 | 159.1 | 166 | 89 | 84 | 56 | 84 | 21 | 14 |
| Ruddy Lugo | GEO | mr | 26 | 3.81 | 2 | 4 | 0 | 64 | 0 | 0 | 0 | 85.0 | 75 | 39 | 36 | 37 | 48 | 4 | 11 |
| Brandon Lyon | Pal | mr | 26 | 3.89 | 2 | 4 | 0 | 68 | 0 | 0 | 0 | 69.1 | 68 | 32 | 30 | 22 | 46 | 7 | 6 |
| Chris Mabeus |   | mr | 27 | 21.60 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.2 | 4 | 4 | 4 | 3 | 2 | 1 | 0 |
| Mike MacDougal |   | mr | 29 | 1.55 | 1 | 1 | 1 | 29 | 0 | 0 | 0 | 29.0 | 21 | 5 | 5 | 6 | 21 | 1 | 6 |
| Greg Maddux | Pal | sp | 40 | 4.20 | 15 | 14 | 0 | 34 | 34 | 0 | 0 | 210.0 | 219 | 109 | 98 | 37 | 117 | 20 | 17 |
| Ryan Madson | CCL | mr | 25 | 5.69 | 11 | 9 | 2 | 50 | 17 | 0 | 0 | 134.1 | 176 | 92 | 85 | 50 | 99 | 20 | 12 |
| Ron Mahay* |   | mr | 35 | 3.95 | 1 | 3 | 0 | 62 | 0 | 0 | 0 | 57.0 | 54 | 30 | 25 | 28 | 56 | 7 | 7 |
| Paul Maholm* |   | sp | 24 | 4.76 | 8 | 10 | 0 | 30 | 30 | 0 | 0 | 176.0 | 202 | 98 | 93 | 81 | 117 | 19 | 23 |
| John Maine | BT | sp | 25 | 3.60 | 6 | 5 | 0 | 16 | 15 | 1 | 1 | 90.0 | 69 | 40 | 36 | 33 | 71 | 15 | 3 |
| Gary Majewski |   | mr | 26 | 4.61 | 4 | 4 | 0 | 65 | 0 | 0 | 0 | 70.1 | 79 | 38 | 36 | 29 | 43 | 5 | 7 |
| Julio Manon |   | mr | 32 | 5.40 | 0 | 1 | 0 | 22 | 0 | 0 | 0 | 20.0 | 23 | 13 | 12 | 16 | 22 | 5 | 0 |
| Shaun Marcum | COP | sp | 24 | 5.06 | 3 | 4 | 0 | 21 | 14 | 0 | 0 | 78.1 | 87 | 44 | 44 | 38 | 65 | 14 | 6 |
| Carlos Marmol | WIZ | sp | 23 | 6.08 | 5 | 7 | 0 | 19 | 13 | 0 | 0 | 77.0 | 71 | 54 | 52 | 59 | 59 | 14 | 2 |
| Mike Maroth* |   | sp | 28 | 4.19 | 5 | 2 | 0 | 13 | 9 | 0 | 0 | 53.2 | 64 | 26 | 25 | 16 | 24 | 11 | 6 |
| Jason Marquis |   | sp | 27 | 6.02 | 14 | 16 | 0 | 33 | 33 | 0 | 0 | 194.1 | 221 | 136 | 130 | 75 | 96 | 35 | 18 |
| Sean Marshall* | LON | sp | 23 | 5.59 | 6 | 9 | 0 | 24 | 24 | 0 | 0 | 125.2 | 132 | 85 | 78 | 59 | 77 | 20 | 12 |
| Damaso Marte* | WIZ | mr | 31 | 3.70 | 1 | 7 | 0 | 75 | 0 | 0 | 0 | 58.1 | 51 | 30 | 24 | 31 | 63 | 5 | 5 |
| Tom Martin* |   | mr | 36 | 5.07 | 2 | 0 | 0 | 68 | 0 | 0 | 0 | 60.1 | 62 | 37 | 34 | 25 | 46 | 4 | 7 |
| Carlos Martinez |   | mr | 24 | 1.74 | 0 | 1 | 0 | 12 | 0 | 0 | 0 | 10.1 | 9 | 2 | 2 | 6 | 11 | 0 | 0 |
| Pedro Martinez | WIZ | sp | 34 | 4.48 | 9 | 8 | 0 | 23 | 23 | 0 | 0 | 132.2 | 108 | 72 | 66 | 39 | 137 | 19 | 7 |
| Nick Masset |   | mr | 24 | 4.15 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 8.2 | 9 | 4 | 4 | 2 | 4 | 0 | 2 |
| Tom Mastny |   | cl | 25 | 5.51 | 0 | 1 | 5 | 15 | 0 | 0 | 0 | 16.1 | 17 | 10 | 10 | 8 | 14 | 1 | 1 |
| Juan Mateo |   | sp | 23 | 5.32 | 1 | 3 | 0 | 11 | 10 | 0 | 0 | 45.2 | 51 | 31 | 27 | 23 | 35 | 6 | 5 |
| Julio Mateo |   | mr | 28 | 4.19 | 9 | 4 | 0 | 48 | 0 | 0 | 0 | 53.2 | 62 | 27 | 25 | 22 | 31 | 6 | 4 |
| Scott Mathieson |   | sp | 22 | 7.47 | 1 | 4 | 0 | 9 | 8 | 0 | 0 | 37.1 | 48 | 36 | 31 | 16 | 28 | 8 | 2 |
| Joe Mays |   | sp | 30 | 8.70 | 0 | 5 | 0 | 13 | 10 | 0 | 0 | 50.2 | 78 | 56 | 49 | 26 | 25 | 11 | 6 |
| Macay McBride* |   | mr | 23 | 3.65 | 4 | 1 | 1 | 71 | 0 | 0 | 0 | 56.2 | 53 | 28 | 23 | 32 | 46 | 2 | 7 |
| Brandon McCarthy |   | mr | 22 | 4.68 | 4 | 7 | 0 | 53 | 2 | 0 | 0 | 84.2 | 77 | 44 | 44 | 33 | 69 | 17 | 9 |
| Seth McClung |   | mr | 25 | 6.29 | 6 | 12 | 6 | 39 | 15 | 0 | 0 | 103.0 | 120 | 77 | 72 | 68 | 59 | 14 | 7 |
| Dustin McGowan |   | mr | 24 | 7.24 | 1 | 2 | 0 | 16 | 3 | 0 | 0 | 27.1 | 35 | 27 | 22 | 25 | 22 | 2 | 1 |
| Marty McLeary |   | mr | 31 | 2.04 | 2 | 0 | 0 | 5 | 2 | 0 | 0 | 17.2 | 17 | 5 | 4 | 6 | 8 | 1 | 2 |
| Brian Meadows |   | mr | 30 | 5.17 | 3 | 6 | 8 | 53 | 0 | 0 | 0 | 69.2 | 90 | 43 | 40 | 15 | 35 | 14 | 6 |
| Gil Meche | CRH | sp | 27 | 4.48 | 11 | 8 | 0 | 32 | 32 | 1 | 0 | 186.2 | 183 | 106 | 93 | 84 | 156 | 24 | 16 |
| Brandon Medders |   | mr | 26 | 3.64 | 5 | 3 | 0 | 60 | 0 | 0 | 0 | 71.2 | 76 | 37 | 29 | 28 | 47 | 5 | 8 |
| Kent Mercker* |   | mr | 38 | 4.13 | 1 | 1 | 1 | 37 | 0 | 0 | 0 | 28.1 | 28 | 15 | 13 | 11 | 17 | 6 | 4 |
| Cla Meredith | WIZ | mr | 23 | 1.07 | 5 | 1 | 0 | 45 | 0 | 0 | 0 | 50.2 | 30 | 6 | 6 | 6 | 37 | 3 | 4 |
| Jose Mesa |   | mr | 40 | 3.86 | 1 | 5 | 1 | 79 | 0 | 0 | 0 | 72.1 | 73 | 32 | 31 | 36 | 39 | 9 | 13 |
| Randy Messenger |   | mr | 24 | 5.67 | 2 | 7 | 0 | 59 | 0 | 0 | 0 | 60.1 | 72 | 42 | 38 | 24 | 45 | 8 | 6 |
| Dan Miceli |   | mr | 35 | 3.94 | 1 | 2 | 4 | 33 | 0 | 0 | 0 | 32.0 | 25 | 17 | 14 | 20 | 18 | 4 | 1 |
| Chris Michalak* |   | sp | 35 | 4.89 | 2 | 4 | 0 | 8 | 6 | 0 | 0 | 35.0 | 42 | 21 | 19 | 16 | 10 | 6 | 6 |
| Andrew Miller* |   | mr | 21 | 6.10 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 10.1 | 8 | 9 | 7 | 10 | 6 | 0 | 1 |
| Matt Miller |   | mr | 34 | 3.45 | 1 | 0 | 0 | 14 | 0 | 0 | 0 | 15.2 | 11 | 6 | 6 | 9 | 12 | 2 | 4 |
| Trever Miller* | CCL | mr | 33 | 3.02 | 2 | 3 | 1 | 70 | 0 | 0 | 0 | 50.2 | 42 | 17 | 17 | 13 | 56 | 7 | 2 |
| Wade Miller |   | sp | 29 | 4.57 | 0 | 2 | 0 | 5 | 5 | 0 | 0 | 21.2 | 19 | 12 | 11 | 18 | 20 | 4 | 0 |
| Kevin Millwood | CCL | sp | 31 | 4.52 | 16 | 12 | 0 | 34 | 34 | 2 | 0 | 215.0 | 228 | 114 | 108 | 53 | 157 | 23 | 21 |
| Eric Milton* |   | sp | 30 | 5.19 | 8 | 8 | 0 | 26 | 26 | 0 | 0 | 152.2 | 163 | 94 | 88 | 42 | 90 | 29 | 7 |
| Zach Miner |   | sp | 24 | 4.84 | 7 | 6 | 0 | 27 | 16 | 1 | 0 | 93.0 | 100 | 53 | 50 | 32 | 59 | 11 | 7 |
| Patrick Misch* |   | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 |
| Sergio Mitre |   | sp | 25 | 5.71 | 1 | 5 | 0 | 15 | 7 | 0 | 0 | 41.0 | 44 | 28 | 26 | 20 | 31 | 7 | 5 |
| Brian Moehler |   | sp | 34 | 6.57 | 7 | 11 | 0 | 29 | 21 | 0 | 0 | 122.0 | 164 | 95 | 89 | 38 | 58 | 19 | 15 |
| Agustin Montero |   | mr | 28 | 5.14 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 14.0 | 15 | 10 | 8 | 2 | 7 | 3 | 2 |
| Juan Morillo |   | sp | 22 | 15.75 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.0 | 8 | 7 | 7 | 3 | 4 | 3 | 0 |
| Matt Morris | CCL | sp | 31 | 4.98 | 10 | 15 | 0 | 33 | 33 | 2 | 0 | 207.2 | 218 | 123 | 115 | 63 | 117 | 22 | 13 |
| Dustin Moseley |   | sp | 24 | 9.00 | 1 | 0 | 0 | 3 | 2 | 0 | 0 | 11.0 | 22 | 11 | 11 | 2 | 3 | 3 | 4 |
| Guillermo Mota |   | mr | 32 | 4.53 | 4 | 3 | 0 | 52 | 0 | 0 | 0 | 55.2 | 55 | 29 | 28 | 24 | 46 | 11 | 3 |
| Jamie Moyer* |   | sp | 43 | 4.30 | 11 | 14 | 0 | 33 | 33 | 2 | 1 | 211.1 | 228 | 110 | 101 | 51 | 108 | 33 | 21 |
| Peter Moylan |   | mr | 27 | 4.80 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 15.0 | 18 | 8 | 8 | 5 | 14 | 1 | 1 |
| Edward Mujica |   | mr | 22 | 2.95 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 18.1 | 25 | 6 | 6 | 0 | 12 | 1 | 1 |
| Mark Mulder* |   | sp | 28 | 7.14 | 6 | 7 | 0 | 17 | 17 | 0 | 0 | 93.1 | 124 | 77 | 74 | 35 | 50 | 19 | 16 |
| Terry Mulholland* |   | mr | 43 | 9.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3.0 | 7 | 3 | 3 | 1 | 1 | 1 | 0 |
| Scott Munter |   | mr | 26 | 8.74 | 0 | 1 | 0 | 27 | 0 | 0 | 0 | 22.2 | 30 | 22 | 22 | 18 | 7 | 1 | 6 |
| Mike Mussina | GEO | sp | 37 | 3.51 | 15 | 7 | 0 | 32 | 32 | 1 | 0 | 197.1 | 184 | 88 | 77 | 35 | 172 | 22 | 19 |
| Brett Myers | Pal | sp | 25 | 3.91 | 12 | 7 | 0 | 31 | 31 | 1 | 0 | 198.0 | 194 | 93 | 86 | 63 | 189 | 29 | 20 |
| Mike Myers* |   | mr | 37 | 3.23 | 1 | 2 | 0 | 62 | 0 | 0 | 0 | 30.2 | 29 | 14 | 11 | 10 | 22 | 3 | 2 |
| Clint Nageotte |   | mr | 25 | 27.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 2 | 3 | 3 | 2 | 1 | 1 | 0 |
| Chris Narveson* |   | mr | 24 | 4.82 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 9.1 | 6 | 5 | 5 | 5 | 12 | 1 | 0 |
| Joe Nathan | WIZ | cl | 31 | 1.58 | 7 | 0 | 36 | 64 | 0 | 0 | 0 | 68.1 | 38 | 12 | 12 | 16 | 95 | 3 | 1 |
| Jeff Nelson |   | mr | 39 | 3.38 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 2.2 | 3 | 1 | 1 | 5 | 2 | 1 | 0 |
| Joe Nelson |   | mr | 31 | 4.43 | 1 | 1 | 9 | 43 | 0 | 0 | 0 | 44.2 | 37 | 22 | 22 | 24 | 44 | 5 | 3 |
| Pat Neshek |   | mr | 25 | 2.19 | 4 | 2 | 0 | 32 | 0 | 0 | 0 | 37.0 | 23 | 9 | 9 | 6 | 53 | 6 | 0 |
| Fernando Nieve |   | mr | 23 | 4.20 | 3 | 3 | 0 | 40 | 11 | 0 | 0 | 96.1 | 87 | 46 | 45 | 41 | 70 | 18 | 9 |
| Dustin Nippert |   | sp | 25 | 11.70 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 10.0 | 15 | 13 | 13 | 7 | 9 | 5 | 2 |
| Ricky Nolasco |   | sp | 23 | 4.82 | 11 | 11 | 0 | 35 | 22 | 0 | 0 | 140.0 | 157 | 86 | 75 | 41 | 99 | 20 | 12 |
| Roberto Novoa |   | mr | 26 | 4.26 | 2 | 1 | 0 | 66 | 0 | 0 | 0 | 76.0 | 77 | 47 | 36 | 32 | 53 | 15 | 9 |
| Leo Nunez |   | mr | 22 | 4.72 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 13.1 | 15 | 7 | 7 | 5 | 7 | 2 | 6 |
| Mike O'Connor* | BT | sp | 25 | 4.80 | 3 | 8 | 0 | 21 | 20 | 0 | 0 | 105.0 | 96 | 61 | 56 | 45 | 59 | 15 | 8 |
| Eric O'Flaherty* |   | mr | 21 | 4.09 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 11.0 | 18 | 9 | 5 | 6 | 6 | 2 | 1 |
| Ryan O'Malley* |   | sp | 26 | 2.13 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 12.2 | 10 | 3 | 3 | 7 | 4 | 0 | 0 |
| Tomo Ohka |   | sp | 30 | 4.82 | 4 | 5 | 0 | 18 | 18 | 0 | 0 | 97.0 | 98 | 58 | 52 | 35 | 50 | 12 | 8 |
| Will Ohman* | MAD | mr | 28 | 4.13 | 1 | 1 | 0 | 78 | 0 | 0 | 0 | 65.1 | 51 | 30 | 30 | 34 | 74 | 6 | 1 |
| Darren Oliver* |   | mr | 35 | 3.44 | 4 | 1 | 0 | 45 | 0 | 0 | 0 | 81.0 | 70 | 33 | 31 | 21 | 60 | 13 | 5 |
| Scott Olsen* | TON | sp | 22 | 4.04 | 12 | 10 | 0 | 31 | 31 | 0 | 0 | 180.2 | 160 | 94 | 81 | 75 | 166 | 23 | 14 |
| Ramon Ortiz |   | sp | 33 | 5.57 | 11 | 16 | 0 | 33 | 33 | 0 | 0 | 190.2 | 230 | 127 | 118 | 64 | 104 | 31 | 14 |
| Russ Ortiz |   | mr | 32 | 8.14 | 0 | 8 | 0 | 26 | 11 | 0 | 0 | 63.0 | 86 | 60 | 57 | 40 | 44 | 18 | 7 |
| Chad Orvella |   | mr | 25 | 7.40 | 1 | 5 | 0 | 22 | 0 | 0 | 0 | 24.1 | 36 | 23 | 20 | 20 | 17 | 6 | 3 |
| Franquelis Osoria |   | mr | 24 | 7.13 | 0 | 2 | 0 | 12 | 0 | 0 | 0 | 17.2 | 27 | 14 | 14 | 9 | 13 | 4 | 4 |
| Roy Oswalt | BT | sp | 28 | 2.98 | 15 | 8 | 0 | 33 | 32 | 2 | 0 | 220.2 | 220 | 76 | 73 | 38 | 166 | 18 | 23 |
| Akinori Otsuka | MAD | cl | 34 | 2.11 | 2 | 4 | 32 | 63 | 0 | 0 | 0 | 59.2 | 53 | 17 | 14 | 11 | 47 | 3 | 8 |
| Henry Owens |   | mr | 27 | 9.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.0 | 4 | 4 | 4 | 4 | 2 | 0 | 1 |
| Vicente Padilla |   | sp | 28 | 4.50 | 15 | 10 | 0 | 33 | 33 | 0 | 0 | 200.0 | 206 | 108 | 100 | 70 | 156 | 21 | 17 |
| Jonathan Papelbon | BON | cl | 25 | 0.92 | 4 | 2 | 35 | 59 | 0 | 0 | 0 | 68.1 | 40 | 8 | 7 | 13 | 75 | 3 | 1 |
| Chan Ho Park |   | sp | 33 | 4.81 | 7 | 7 | 0 | 24 | 21 | 1 | 1 | 136.2 | 146 | 81 | 73 | 44 | 96 | 20 | 9 |
| Chad Paronto | CCL | mr | 30 | 3.18 | 2 | 3 | 0 | 65 | 0 | 0 | 0 | 56.2 | 53 | 23 | 20 | 19 | 41 | 5 | 5 |
| John Patterson |   | sp | 28 | 4.43 | 1 | 2 | 0 | 8 | 8 | 0 | 0 | 40.2 | 36 | 21 | 20 | 9 | 42 | 4 | 1 |
| David Pauley |   | sp | 23 | 7.88 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 16.0 | 31 | 14 | 14 | 6 | 10 | 1 | 4 |
| Jake Peavy | MUL | sp | 25 | 4.09 | 11 | 14 | 0 | 32 | 32 | 2 | 0 | 202.1 | 187 | 93 | 92 | 62 | 215 | 23 | 13 |
| Mike Pelfrey |   | sp | 22 | 5.48 | 2 | 1 | 0 | 4 | 4 | 0 | 0 | 21.1 | 25 | 14 | 13 | 12 | 13 | 1 | 4 |
| Tony Pena |   | mr | 24 | 5.58 | 3 | 4 | 1 | 25 | 0 | 0 | 0 | 30.2 | 36 | 21 | 19 | 8 | 21 | 6 | 1 |
| Hayden Penn |   | sp | 21 | 15.10 | 0 | 4 | 0 | 6 | 6 | 0 | 0 | 19.2 | 38 | 33 | 33 | 13 | 8 | 8 | 0 |
| Brad Penny | LON | sp | 28 | 4.33 | 16 | 9 | 0 | 34 | 33 | 0 | 0 | 189.0 | 206 | 94 | 91 | 54 | 148 | 19 | 21 |
| Joel Peralta |   | mr | 30 | 4.40 | 1 | 3 | 1 | 64 | 0 | 0 | 0 | 73.2 | 74 | 37 | 36 | 17 | 57 | 10 | 9 |
| Beltran Perez |   | mr | 24 | 3.86 | 2 | 1 | 0 | 8 | 3 | 0 | 0 | 21.0 | 16 | 9 | 9 | 13 | 9 | 3 | 1 |
| Juan Perez* |   | mr | 27 | 8.10 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 3.1 | 5 | 3 | 3 | 1 | 3 | 1 | 1 |
| Odalis Perez* |   | sp | 29 | 6.20 | 6 | 8 | 0 | 32 | 20 | 0 | 0 | 126.1 | 169 | 93 | 87 | 31 | 81 | 18 | 8 |
| Oliver Perez* |   | sp | 24 | 6.55 | 3 | 13 | 0 | 22 | 22 | 1 | 1 | 112.2 | 129 | 90 | 82 | 68 | 102 | 20 | 10 |
| Rafael Perez* |   | mr | 24 | 4.38 | 0 | 0 | 0 | 18 | 0 | 0 | 0 | 12.1 | 10 | 6 | 6 | 6 | 15 | 2 | 0 |
| Glen Perkins* |   | mr | 23 | 1.59 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.2 | 3 | 1 | 1 | 0 | 6 | 0 | 0 |
| Yusmeiro Petit |   | mr | 21 | 9.57 | 1 | 1 | 0 | 15 | 1 | 0 | 0 | 26.1 | 46 | 28 | 28 | 9 | 20 | 7 | 3 |
| Andy Pettitte* |   | sp | 34 | 4.20 | 14 | 13 | 0 | 36 | 35 | 2 | 1 | 214.1 | 238 | 114 | 100 | 70 | 178 | 27 | 26 |
| Joel Pineiro |   | sp | 27 | 6.36 | 8 | 13 | 1 | 40 | 25 | 1 | 0 | 165.2 | 209 | 123 | 117 | 64 | 87 | 23 | 21 |
| Renyel Pinto* |   | mr | 23 | 3.03 | 0 | 0 | 1 | 27 | 0 | 0 | 0 | 29.2 | 20 | 12 | 10 | 27 | 36 | 3 | 6 |
| Cliff Politte |   | mr | 32 | 8.70 | 2 | 2 | 0 | 30 | 0 | 0 | 0 | 30.0 | 47 | 30 | 29 | 15 | 15 | 9 | 2 |
| Sidney Ponson |   | sp | 29 | 6.25 | 4 | 5 | 0 | 19 | 16 | 0 | 0 | 85.0 | 108 | 62 | 59 | 36 | 48 | 10 | 14 |
| Mark Prior |   | sp | 25 | 7.21 | 1 | 6 | 0 | 9 | 9 | 0 | 0 | 43.2 | 46 | 39 | 35 | 28 | 38 | 9 | 3 |
| Scott Proctor | EDG | mr | 29 | 3.52 | 6 | 4 | 1 | 83 | 0 | 0 | 0 | 102.1 | 89 | 41 | 40 | 33 | 89 | 12 | 7 |
| J.J. Putz | MID | cl | 29 | 2.30 | 4 | 1 | 36 | 72 | 0 | 0 | 0 | 78.1 | 59 | 20 | 20 | 13 | 104 | 4 | 5 |
| Chad Qualls | LON | mr | 27 | 3.76 | 7 | 3 | 0 | 81 | 0 | 0 | 0 | 88.2 | 76 | 38 | 37 | 28 | 56 | 10 | 17 |
| Brad Radke | BON | sp | 33 | 4.32 | 12 | 9 | 0 | 28 | 28 | 0 | 0 | 162.1 | 197 | 87 | 78 | 32 | 83 | 24 | 16 |
| Elizardo Ramirez |   | sp | 23 | 5.37 | 4 | 9 | 0 | 21 | 19 | 0 | 0 | 104.0 | 123 | 70 | 62 | 29 | 69 | 14 | 8 |
| Horacio Ramirez* | MUL | sp | 26 | 4.48 | 5 | 5 | 0 | 14 | 14 | 0 | 0 | 76.1 | 85 | 42 | 38 | 31 | 37 | 6 | 13 |
| Ramon Ramirez | LON | mr | 24 | 3.46 | 4 | 3 | 0 | 61 | 0 | 0 | 0 | 67.2 | 58 | 28 | 26 | 27 | 61 | 5 | 4 |
| Santiago Ramirez |   | mr | 27 | 8.10 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 6 | 3 | 3 | 2 | 1 | 1 | 0 |
| Darrell Rasner |   | sp | 25 | 4.43 | 3 | 1 | 0 | 6 | 3 | 0 | 0 | 20.1 | 18 | 10 | 10 | 5 | 11 | 2 | 1 |
| Jon Rauch |   | mr | 27 | 3.35 | 4 | 5 | 2 | 85 | 0 | 0 | 0 | 91.1 | 78 | 37 | 34 | 36 | 86 | 13 | 2 |
| Chris Ray | MID | cl | 24 | 2.73 | 4 | 4 | 33 | 61 | 0 | 0 | 0 | 66.0 | 45 | 22 | 20 | 27 | 51 | 10 | 3 |
| Ken Ray |   | mr | 31 | 4.52 | 1 | 1 | 5 | 69 | 0 | 0 | 0 | 67.2 | 66 | 36 | 34 | 38 | 50 | 9 | 6 |
| Britt Reames |   | mr | 32 | 9.82 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.1 | 11 | 8 | 8 | 5 | 6 | 2 | 1 |
| Mark Redman* |   | sp | 32 | 5.71 | 11 | 10 | 0 | 29 | 29 | 2 | 1 | 167.0 | 202 | 110 | 106 | 63 | 76 | 19 | 22 |
| Chris Reitsma |   | cl | 28 | 8.68 | 1 | 2 | 8 | 27 | 0 | 0 | 0 | 28.0 | 46 | 27 | 27 | 8 | 13 | 7 | 0 |
| Mike Remlinger* |   | mr | 40 | 4.03 | 2 | 4 | 2 | 36 | 0 | 0 | 0 | 22.1 | 27 | 11 | 10 | 9 | 19 | 2 | 3 |
| Chris Resop |   | mr | 23 | 3.38 | 1 | 2 | 0 | 22 | 0 | 0 | 0 | 21.1 | 26 | 9 | 8 | 16 | 10 | 1 | 5 |
| Anthony Reyes |   | sp | 24 | 5.06 | 5 | 8 | 0 | 17 | 17 | 1 | 0 | 85.1 | 84 | 48 | 48 | 34 | 72 | 17 | 7 |
| Dennys Reyes* | BON | mr | 29 | 0.89 | 5 | 0 | 0 | 66 | 0 | 0 | 0 | 50.2 | 35 | 8 | 5 | 15 | 49 | 3 | 8 |
| John Rheinecker* |   | sp | 27 | 5.86 | 4 | 6 | 0 | 21 | 13 | 0 | 0 | 70.2 | 104 | 46 | 46 | 19 | 28 | 6 | 9 |
| Arthur Rhodes* |   | mr | 36 | 5.32 | 0 | 5 | 4 | 55 | 0 | 0 | 0 | 45.2 | 47 | 27 | 27 | 30 | 48 | 2 | 3 |
| Juan Rincon | COP | mr | 27 | 2.91 | 3 | 1 | 1 | 75 | 0 | 0 | 0 | 74.1 | 76 | 30 | 24 | 24 | 65 | 2 | 9 |
| Ricardo Rincon* |   | mr | 36 | 10.80 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3.1 | 6 | 4 | 4 | 4 | 6 | 1 | 0 |
| Royce Ring* |   | mr | 25 | 2.13 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 12.2 | 7 | 3 | 3 | 3 | 8 | 2 | 0 |
| David Riske | CRH | mr | 29 | 3.89 | 1 | 2 | 0 | 41 | 0 | 0 | 0 | 44.0 | 40 | 20 | 19 | 17 | 28 | 6 | 3 |
| Mariano Rivera | ROK | cl | 36 | 1.80 | 5 | 5 | 34 | 63 | 0 | 0 | 0 | 75.0 | 61 | 16 | 15 | 11 | 55 | 3 | 10 |
| Saul Rivera |   | mr | 28 | 3.43 | 3 | 0 | 1 | 54 | 0 | 0 | 0 | 60.1 | 59 | 28 | 23 | 32 | 41 | 4 | 3 |
| Sendy Rleal |   | mr | 26 | 4.44 | 1 | 1 | 0 | 42 | 0 | 0 | 0 | 46.2 | 48 | 25 | 23 | 23 | 19 | 10 | 8 |
| Nate Robertson* |   | sp | 28 | 3.84 | 13 | 13 | 0 | 32 | 32 | 1 | 0 | 208.2 | 206 | 98 | 89 | 67 | 137 | 29 | 30 |
| Fernando Rodney | OTR | mr | 29 | 3.52 | 7 | 4 | 7 | 63 | 0 | 0 | 0 | 71.2 | 51 | 36 | 28 | 34 | 65 | 6 | 4 |
| Eddy Rodriguez |   | mr | 24 | 7.20 | 1 | 1 | 0 | 9 | 0 | 0 | 0 | 15.0 | 17 | 14 | 12 | 10 | 11 | 5 | 1 |
| Felix Rodriguez |   | mr | 33 | 7.67 | 1 | 1 | 0 | 31 | 0 | 0 | 0 | 29.1 | 32 | 25 | 25 | 16 | 15 | 5 | 0 |
| Francisco Rodriguez | BON | cl | 24 | 1.73 | 2 | 3 | 47 | 69 | 0 | 0 | 0 | 73.0 | 52 | 16 | 14 | 28 | 98 | 6 | 4 |
| Wandy Rodriguez* |   | sp | 27 | 5.64 | 9 | 10 | 0 | 30 | 24 | 0 | 0 | 135.2 | 154 | 96 | 85 | 63 | 98 | 17 | 20 |
| Brian Rogers |   | mr | 23 | 8.31 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 8.2 | 11 | 8 | 8 | 2 | 7 | 2 | 1 |
| Kenny Rogers* | EDG | sp | 41 | 3.84 | 17 | 8 | 0 | 34 | 33 | 0 | 0 | 204.0 | 195 | 97 | 87 | 62 | 99 | 23 | 25 |
| Davis Romero* |   | mr | 23 | 3.86 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 16.1 | 19 | 7 | 7 | 6 | 10 | 1 | 3 |
| J.C. Romero* |   | mr | 30 | 6.70 | 1 | 2 | 0 | 65 | 0 | 0 | 0 | 48.1 | 57 | 40 | 36 | 28 | 31 | 3 | 4 |
| Matt Roney |   | mr | 26 | 4.50 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 4.0 | 5 | 2 | 2 | 1 | 0 | 0 | 0 |
| Francisco Rosario |   | mr | 25 | 6.65 | 1 | 2 | 0 | 17 | 1 | 0 | 0 | 23.0 | 24 | 17 | 17 | 16 | 21 | 4 | 1 |
| Josh Rupe |   | mr | 23 | 3.41 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 29.0 | 33 | 11 | 11 | 9 | 14 | 2 | 5 |
| Glendon Rusch* |   | mr | 31 | 7.46 | 3 | 8 | 0 | 25 | 9 | 0 | 0 | 66.1 | 86 | 57 | 55 | 33 | 59 | 21 | 6 |
| B.J. Ryan* | MID | cl | 30 | 1.37 | 2 | 2 | 38 | 65 | 0 | 0 | 0 | 72.1 | 42 | 12 | 11 | 20 | 86 | 3 | 8 |
| Jae Kuk Ryu |   | mr | 23 | 8.40 | 0 | 1 | 0 | 10 | 1 | 0 | 0 | 15.0 | 23 | 14 | 14 | 6 | 17 | 7 | 0 |
| Kirk Saarloos |   | mr | 27 | 4.75 | 7 | 7 | 2 | 35 | 16 | 0 | 0 | 121.1 | 149 | 70 | 64 | 53 | 52 | 19 | 17 |
| C.C. Sabathia* | CRH | sp | 25 | 3.22 | 12 | 11 | 0 | 28 | 28 | 6 | 2 | 192.2 | 182 | 83 | 69 | 44 | 172 | 17 | 16 |
| Billy Sadler |   | mr | 24 | 6.75 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.0 | 5 | 3 | 3 | 2 | 6 | 2 | 0 |
| Takashi Saito | Pal | cl | 36 | 2.07 | 6 | 2 | 24 | 72 | 0 | 0 | 0 | 78.1 | 48 | 19 | 18 | 23 | 107 | 3 | 6 |
| Juan Salas |   | mr | 27 | 5.40 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 10.0 | 13 | 7 | 6 | 3 | 8 | 1 | 0 |
| Chris Sampson |   | mr | 28 | 2.12 | 2 | 1 | 0 | 12 | 3 | 0 | 0 | 34.0 | 25 | 10 | 8 | 5 | 15 | 3 | 3 |
| Brian Sanches |   | mr | 27 | 5.91 | 0 | 0 | 0 | 18 | 0 | 0 | 0 | 21.1 | 23 | 14 | 14 | 13 | 22 | 5 | 0 |
| Anibal Sanchez | MAD | sp | 22 | 2.83 | 10 | 3 | 0 | 18 | 17 | 2 | 1 | 114.1 | 90 | 39 | 36 | 46 | 72 | 9 | 11 |
| Duaner Sanchez | MAD | mr | 26 | 2.60 | 5 | 1 | 0 | 49 | 0 | 0 | 0 | 55.1 | 43 | 19 | 16 | 24 | 44 | 3 | 12 |
| Jonathan Sanchez* |   | mr | 23 | 4.95 | 3 | 1 | 0 | 27 | 4 | 0 | 0 | 40.0 | 39 | 26 | 22 | 23 | 33 | 2 | 3 |
| Ervin Santana | BON | sp | 23 | 4.28 | 16 | 8 | 0 | 33 | 33 | 0 | 0 | 204.0 | 181 | 106 | 97 | 70 | 141 | 21 | 19 |
| Johan Santana* | ROK | sp | 27 | 2.77 | 19 | 6 | 0 | 34 | 34 | 1 | 0 | 233.2 | 186 | 79 | 72 | 47 | 245 | 24 | 10 |
| Julio Santana |   | mr | 33 | 7.56 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.1 | 8 | 9 | 7 | 9 | 4 | 1 | 1 |
| Victor Santos |   | sp | 29 | 5.70 | 5 | 9 | 0 | 25 | 19 | 0 | 0 | 115.1 | 150 | 80 | 73 | 42 | 81 | 16 | 10 |
| Dennis Sarfate |   | mr | 25 | 4.32 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 8.1 | 9 | 4 | 4 | 4 | 11 | 0 | 0 |
| Scott Sauerbeck* |   | mr | 34 | 4.97 | 0 | 1 | 0 | 46 | 0 | 0 | 0 | 25.1 | 22 | 17 | 14 | 18 | 17 | 3 | 3 |
| Joe Saunders* | MID | sp | 25 | 4.71 | 7 | 3 | 0 | 13 | 13 | 0 | 0 | 70.2 | 71 | 42 | 37 | 29 | 51 | 6 | 10 |
| Curt Schilling | CRH | sp | 39 | 3.97 | 15 | 7 | 0 | 31 | 31 | 0 | 0 | 204.0 | 220 | 90 | 90 | 28 | 183 | 28 | 15 |
| Jason Schmidt | WIZ | sp | 33 | 3.59 | 11 | 9 | 0 | 32 | 32 | 3 | 1 | 213.1 | 189 | 94 | 85 | 80 | 180 | 21 | 11 |
| Scott Schoeneweis* |   | mr | 32 | 4.88 | 4 | 2 | 4 | 71 | 0 | 0 | 0 | 51.2 | 48 | 28 | 28 | 24 | 29 | 4 | 7 |
| Chris Schroder |   | mr | 27 | 6.35 | 0 | 2 | 0 | 21 | 0 | 0 | 0 | 28.1 | 23 | 21 | 20 | 15 | 39 | 7 | 2 |
| Rudy Seanez |   | mr | 37 | 4.92 | 3 | 3 | 0 | 49 | 0 | 0 | 0 | 53.0 | 58 | 32 | 29 | 32 | 54 | 8 | 2 |
| Bobby Seay* |   | mr | 28 | 6.46 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 15.1 | 14 | 11 | 11 | 9 | 12 | 1 | 1 |
| Aaron Sele |   | sp | 36 | 4.53 | 8 | 6 | 0 | 28 | 15 | 0 | 0 | 103.1 | 120 | 57 | 52 | 30 | 57 | 11 | 11 |
| Jae Seo |   | sp | 29 | 5.33 | 3 | 12 | 0 | 36 | 26 | 0 | 0 | 157.0 | 197 | 101 | 93 | 56 | 88 | 31 | 15 |
| Brian Shackelford* |   | mr | 29 | 7.16 | 1 | 0 | 0 | 26 | 0 | 0 | 0 | 16.1 | 18 | 13 | 13 | 10 | 15 | 4 | 0 |
| Josh Sharpless |   | mr | 25 | 1.50 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 12.0 | 7 | 2 | 2 | 11 | 7 | 0 | 0 |
| Ben Sheets | TON | sp | 27 | 3.82 | 6 | 7 | 0 | 17 | 17 | 0 | 0 | 106.0 | 105 | 47 | 45 | 11 | 116 | 9 | 3 |
| George Sherrill* | ROK | mr | 29 | 4.28 | 2 | 4 | 1 | 72 | 0 | 0 | 0 | 40.0 | 30 | 19 | 19 | 27 | 42 | 0 | 3 |
| James Shields | BON | sp | 24 | 4.84 | 6 | 8 | 0 | 21 | 21 | 1 | 0 | 124.2 | 141 | 69 | 67 | 38 | 104 | 18 | 9 |
| Scot Shields | ROK | mr | 30 | 2.87 | 7 | 7 | 2 | 74 | 0 | 0 | 0 | 87.2 | 70 | 30 | 28 | 24 | 84 | 8 | 9 |
| Jason Shiell |   | sp | 29 | 8.62 | 0 | 2 | 0 | 4 | 3 | 0 | 0 | 15.2 | 23 | 15 | 15 | 9 | 14 | 5 | 1 |
| Brian Shouse* | OTR | mr | 37 | 3.99 | 1 | 3 | 2 | 65 | 0 | 0 | 0 | 38.1 | 40 | 18 | 17 | 18 | 23 | 4 | 4 |
| Brian Sikorski |   | mr | 31 | 5.03 | 3 | 2 | 0 | 30 | 0 | 0 | 0 | 34.0 | 36 | 19 | 19 | 7 | 38 | 8 | 0 |
| Carlos Silva |   | sp | 27 | 5.94 | 11 | 15 | 0 | 36 | 31 | 0 | 0 | 180.1 | 246 | 130 | 119 | 32 | 70 | 38 | 16 |
| Allan Simpson |   | mr | 28 | 3.38 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 1 | 2 | 1 | 4 | 5 | 0 | 0 |
| Andrew Sisco* |   | mr | 23 | 7.10 | 1 | 3 | 1 | 65 | 0 | 0 | 0 | 58.1 | 66 | 47 | 46 | 40 | 52 | 8 | 4 |
| Doug Slaten* |   | mr | 26 | 0.00 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 5.2 | 3 | 0 | 0 | 2 | 3 | 0 | 1 |
| Brian Slocum |   | mr | 25 | 5.60 | 0 | 0 | 0 | 8 | 2 | 0 | 0 | 17.2 | 27 | 11 | 11 | 9 | 11 | 3 | 3 |
| Aaron Small |   | mr | 34 | 8.46 | 0 | 3 | 0 | 11 | 3 | 0 | 0 | 27.2 | 42 | 29 | 26 | 12 | 12 | 9 | 4 |
| Matt Smith* |   | mr | 27 | 0.87 | 0 | 1 | 0 | 26 | 0 | 0 | 0 | 20.2 | 7 | 2 | 2 | 12 | 21 | 0 | 3 |
| Mike Smith |   | sp | 28 | 12.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 3.0 | 5 | 4 | 4 | 3 | 1 | 1 | 0 |
| Travis Smith |   | sp | 33 | 4.15 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.1 | 5 | 4 | 2 | 1 | 1 | 0 | 1 |
| John Smoltz | WIZ | sp | 39 | 3.49 | 16 | 9 | 0 | 35 | 35 | 3 | 1 | 232.0 | 221 | 93 | 90 | 55 | 211 | 23 | 20 |
| Ian Snell |   | sp | 24 | 4.74 | 14 | 11 | 0 | 32 | 32 | 0 | 0 | 186.0 | 198 | 104 | 98 | 74 | 169 | 29 | 14 |
| Kyle Snyder |   | sp | 28 | 6.56 | 4 | 5 | 0 | 17 | 11 | 0 | 0 | 60.1 | 87 | 51 | 44 | 20 | 57 | 12 | 5 |
| Alay Soler |   | sp | 26 | 6.00 | 2 | 3 | 0 | 8 | 8 | 1 | 1 | 45.0 | 50 | 33 | 30 | 21 | 23 | 7 | 1 |
| Rafael Soriano | GEO | mr | 26 | 2.25 | 1 | 2 | 2 | 53 | 0 | 0 | 0 | 60.0 | 44 | 15 | 15 | 21 | 65 | 6 | 4 |
| Jorge Sosa |   | mr | 29 | 5.42 | 3 | 11 | 4 | 45 | 13 | 0 | 0 | 118.0 | 138 | 79 | 71 | 40 | 75 | 30 | 9 |
| Jeremy Sowers* | EDG | sp | 23 | 3.57 | 7 | 4 | 0 | 14 | 14 | 2 | 2 | 88.1 | 85 | 36 | 35 | 20 | 35 | 10 | 10 |
| Justin Speier | MID | mr | 32 | 2.98 | 2 | 0 | 0 | 58 | 0 | 0 | 0 | 51.1 | 47 | 18 | 17 | 21 | 55 | 5 | 1 |
| Russ Springer | WIZ | mr | 37 | 3.47 | 1 | 1 | 0 | 72 | 0 | 0 | 0 | 59.2 | 46 | 23 | 23 | 16 | 46 | 10 | 2 |
| Chris Spurling |   | mr | 29 | 5.06 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 21.1 | 25 | 12 | 12 | 8 | 7 | 5 | 2 |
| Jason Standridge |   | mr | 27 | 4.82 | 1 | 1 | 0 | 21 | 0 | 0 | 0 | 18.2 | 17 | 14 | 10 | 14 | 18 | 2 | 1 |
| Mike Stanton* |   | mr | 39 | 3.99 | 7 | 7 | 8 | 82 | 0 | 0 | 0 | 67.2 | 70 | 30 | 30 | 27 | 48 | 2 | 5 |
| Tim Stauffer | MAD | sp | 24 | 1.50 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6.0 | 3 | 2 | 1 | 1 | 2 | 0 | 0 |
| Steve Stemle |   | mr | 29 | 15.00 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 6.0 | 15 | 10 | 10 | 3 | 0 | 1 | 1 |
| Phil Stockman |   | mr | 26 | 2.25 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 3 | 1 | 1 | 4 | 4 | 0 | 0 |
| Brian Stokes |   | sp | 26 | 4.88 | 1 | 0 | 0 | 5 | 4 | 0 | 0 | 24.0 | 31 | 13 | 13 | 9 | 15 | 2 | 0 |
| Huston Street | GEO | cl | 22 | 3.31 | 4 | 4 | 37 | 69 | 0 | 0 | 0 | 70.2 | 64 | 28 | 26 | 13 | 67 | 4 | 1 |
| Eric Stults* |   | mr | 26 | 5.60 | 1 | 0 | 0 | 6 | 2 | 0 | 0 | 17.2 | 17 | 12 | 11 | 7 | 5 | 4 | 4 |
| Tanyon Sturtze |   | mr | 35 | 7.59 | 0 | 0 | 0 | 18 | 0 | 0 | 0 | 10.2 | 17 | 10 | 9 | 6 | 6 | 3 | 1 |
| Jeff Suppan |   | sp | 31 | 4.12 | 12 | 7 | 0 | 32 | 32 | 0 | 0 | 190.0 | 207 | 100 | 87 | 69 | 104 | 21 | 24 |
| Brian Sweeney | MUL | mr | 32 | 3.20 | 2 | 0 | 2 | 37 | 0 | 0 | 0 | 56.1 | 53 | 22 | 20 | 16 | 23 | 6 | 7 |
| Jon Switzer* |   | mr | 26 | 4.54 | 2 | 2 | 0 | 40 | 0 | 0 | 0 | 33.2 | 38 | 19 | 17 | 19 | 18 | 5 | 3 |
| Brian Tallet* |   | mr | 28 | 3.81 | 3 | 0 | 0 | 44 | 1 | 0 | 0 | 54.1 | 45 | 24 | 23 | 31 | 37 | 5 | 3 |
| Taylor Tankersley* | MAD | mr | 23 | 2.85 | 2 | 1 | 3 | 49 | 0 | 0 | 0 | 41.0 | 33 | 14 | 13 | 26 | 46 | 4 | 4 |
| Jack Taschner* |   | mr | 28 | 8.38 | 0 | 1 | 0 | 24 | 0 | 0 | 0 | 19.1 | 31 | 23 | 18 | 7 | 15 | 4 | 1 |
| Jordan Tata |   | mr | 24 | 6.14 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 14.2 | 14 | 11 | 10 | 7 | 6 | 1 | 1 |
| Ty Taubenheim |   | sp | 23 | 4.89 | 1 | 5 | 0 | 12 | 7 | 0 | 0 | 35.0 | 40 | 22 | 19 | 18 | 26 | 5 | 1 |
| Julian Tavarez |   | mr | 33 | 4.47 | 5 | 4 | 1 | 58 | 6 | 1 | 0 | 98.2 | 110 | 54 | 49 | 44 | 56 | 10 | 24 |
| Robinson Tejeda |   | sp | 24 | 4.28 | 5 | 5 | 0 | 14 | 14 | 0 | 0 | 73.2 | 83 | 40 | 35 | 32 | 40 | 10 | 7 |
| Brad Thompson |   | mr | 24 | 3.34 | 1 | 2 | 0 | 43 | 1 | 0 | 0 | 56.2 | 58 | 23 | 21 | 20 | 32 | 4 | 9 |
| Mike Thompson |   | sp | 25 | 4.99 | 4 | 5 | 0 | 19 | 16 | 0 | 0 | 92.0 | 103 | 56 | 51 | 30 | 35 | 13 | 11 |
| John Thomson |   | sp | 32 | 4.82 | 2 | 7 | 0 | 18 | 15 | 0 | 0 | 80.1 | 93 | 55 | 43 | 32 | 46 | 11 | 7 |
| Matt Thornton* | CRH | mr | 29 | 3.33 | 5 | 3 | 2 | 63 | 0 | 0 | 0 | 54.0 | 46 | 20 | 20 | 21 | 49 | 5 | 5 |
| Mike Timlin | OTR | mr | 40 | 4.36 | 6 | 6 | 9 | 68 | 0 | 0 | 0 | 64.0 | 78 | 33 | 31 | 16 | 30 | 7 | 5 |
| Brett Tomko |   | mr | 33 | 4.73 | 8 | 7 | 0 | 44 | 15 | 0 | 0 | 112.1 | 123 | 67 | 59 | 29 | 76 | 17 | 5 |
| Salomon Torres | CCL | mr | 34 | 3.28 | 3 | 6 | 12 | 94 | 0 | 0 | 0 | 93.1 | 98 | 42 | 34 | 38 | 72 | 6 | 13 |
| Josh Towers |   | sp | 29 | 8.42 | 2 | 10 | 0 | 15 | 12 | 0 | 0 | 62.0 | 93 | 62 | 58 | 17 | 35 | 17 | 5 |
| Billy Traber* |   | sp | 26 | 6.44 | 4 | 3 | 0 | 15 | 8 | 0 | 0 | 43.1 | 53 | 33 | 31 | 14 | 25 | 5 | 4 |
| Sean Tracey |   | mr | 25 | 3.38 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.0 | 4 | 3 | 3 | 5 | 3 | 2 | 1 |
| Steve Trachsel |   | sp | 35 | 4.97 | 15 | 8 | 0 | 30 | 30 | 1 | 0 | 164.2 | 185 | 94 | 91 | 78 | 79 | 23 | 9 |
| Derrick Turnbow |   | cl | 28 | 6.87 | 4 | 9 | 24 | 64 | 0 | 0 | 0 | 56.1 | 56 | 51 | 43 | 39 | 69 | 8 | 4 |
| Jose Valverde | WIZ | cl | 26 | 5.84 | 2 | 3 | 18 | 44 | 0 | 0 | 0 | 49.1 | 50 | 32 | 32 | 22 | 69 | 6 | 0 |
| Jermaine Van Buren |   | mr | 25 | 11.77 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 13.0 | 14 | 17 | 17 | 15 | 8 | 1 | 3 |
| Claudio Vargas |   | sp | 28 | 4.83 | 12 | 10 | 0 | 31 | 30 | 0 | 0 | 167.2 | 185 | 101 | 90 | 52 | 123 | 27 | 11 |
| Jason Vargas* |   | mr | 23 | 7.33 | 1 | 2 | 0 | 12 | 5 | 0 | 0 | 43.0 | 50 | 39 | 35 | 30 | 25 | 9 | 3 |
| Javier Vazquez | Pal | sp | 29 | 4.84 | 11 | 12 | 0 | 33 | 32 | 1 | 0 | 202.2 | 206 | 116 | 109 | 56 | 184 | 23 | 15 |
| Mike Venafro* |   | mr | 32 | 2.45 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 3.2 | 3 | 1 | 1 | 3 | 2 | 0 | 1 |
| Jose Veras |   | mr | 25 | 4.09 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 11.0 | 8 | 5 | 5 | 5 | 6 | 2 | 1 |
| Justin Verlander | COP | sp | 23 | 3.63 | 17 | 9 | 0 | 30 | 30 | 1 | 1 | 186.0 | 187 | 78 | 75 | 60 | 124 | 21 | 21 |
| Carlos Villanueva | TON | sp | 22 | 3.69 | 2 | 2 | 0 | 10 | 6 | 0 | 0 | 53.2 | 43 | 22 | 22 | 11 | 39 | 8 | 7 |
| Oscar Villarreal |   | mr | 24 | 3.61 | 9 | 1 | 0 | 58 | 4 | 0 | 0 | 92.1 | 93 | 41 | 37 | 27 | 55 | 13 | 8 |
| Ron Villone* |   | mr | 36 | 5.04 | 3 | 3 | 0 | 70 | 0 | 0 | 0 | 80.1 | 75 | 48 | 45 | 51 | 72 | 9 | 2 |
| Luis Vizcaino | LON | mr | 31 | 3.58 | 4 | 6 | 0 | 70 | 0 | 0 | 0 | 65.1 | 51 | 26 | 26 | 29 | 72 | 8 | 5 |
| Ryan Vogelsong |   | mr | 28 | 6.39 | 0 | 0 | 0 | 20 | 0 | 0 | 0 | 38.0 | 44 | 27 | 27 | 16 | 27 | 2 | 2 |
| Edinson Volquez |   | sp | 22 | 7.29 | 1 | 6 | 0 | 8 | 8 | 0 | 0 | 33.1 | 52 | 28 | 27 | 17 | 15 | 7 | 3 |
| Doug Waechter |   | sp | 25 | 6.62 | 1 | 4 | 0 | 11 | 10 | 0 | 0 | 53.0 | 67 | 40 | 39 | 19 | 25 | 6 | 1 |
| Billy Wagner* | BT | cl | 34 | 2.24 | 3 | 2 | 40 | 70 | 0 | 0 | 0 | 72.1 | 59 | 22 | 18 | 21 | 94 | 7 | 2 |
| Ryan Wagner |   | mr | 23 | 4.70 | 3 | 3 | 0 | 26 | 0 | 0 | 0 | 30.2 | 36 | 21 | 16 | 15 | 20 | 3 | 1 |
| Adam Wainwright | MAD | mr | 24 | 3.12 | 2 | 1 | 3 | 61 | 0 | 0 | 0 | 75.0 | 64 | 26 | 26 | 22 | 72 | 6 | 5 |
| Tim Wakefield | OTR | sp | 39 | 4.63 | 7 | 11 | 0 | 23 | 23 | 1 | 0 | 140.0 | 135 | 80 | 72 | 51 | 90 | 19 | 6 |
| Jamie Walker* | OTR | mr | 34 | 2.81 | 0 | 1 | 0 | 56 | 0 | 0 | 0 | 48.0 | 47 | 15 | 15 | 8 | 37 | 8 | 3 |
| Pete Walker |   | mr | 37 | 5.40 | 1 | 1 | 1 | 23 | 0 | 0 | 0 | 30.0 | 37 | 24 | 18 | 13 | 27 | 5 | 3 |
| Tyler Walker |   | cl | 30 | 7.11 | 1 | 4 | 10 | 26 | 0 | 0 | 0 | 25.1 | 27 | 20 | 20 | 12 | 19 | 1 | 2 |
| Les Walrond* |   | mr | 29 | 6.23 | 0 | 1 | 0 | 10 | 2 | 0 | 0 | 17.1 | 19 | 13 | 12 | 12 | 21 | 2 | 0 |
| Chien-Ming Wang | COP | sp | 26 | 3.63 | 19 | 6 | 1 | 34 | 33 | 2 | 1 | 218.0 | 233 | 92 | 88 | 52 | 76 | 12 | 33 |
| John Wasdin |   | sp | 33 | 5.10 | 2 | 2 | 0 | 9 | 5 | 0 | 0 | 30.0 | 33 | 19 | 17 | 13 | 16 | 6 | 1 |
| Jarrod Washburn* |   | sp | 31 | 4.67 | 8 | 14 | 0 | 31 | 31 | 0 | 0 | 187.0 | 198 | 103 | 97 | 55 | 103 | 25 | 13 |
| David Weathers | TON | mr | 36 | 3.54 | 4 | 4 | 12 | 67 | 0 | 0 | 0 | 73.2 | 61 | 31 | 29 | 34 | 50 | 12 | 5 |
| Jeff Weaver |   | sp | 29 | 5.76 | 8 | 14 | 0 | 31 | 31 | 0 | 0 | 172.0 | 213 | 117 | 110 | 47 | 107 | 34 | 13 |
| Jered Weaver | OTR | sp | 23 | 2.56 | 11 | 2 | 0 | 19 | 19 | 0 | 0 | 123.0 | 94 | 36 | 35 | 33 | 105 | 15 | 5 |
| Brandon Webb | TON | sp | 27 | 3.10 | 16 | 8 | 0 | 33 | 33 | 5 | 3 | 235.0 | 216 | 91 | 81 | 50 | 178 | 15 | 29 |
| Todd Wellemeyer |   | mr | 27 | 4.14 | 1 | 4 | 1 | 46 | 0 | 0 | 0 | 78.1 | 68 | 38 | 36 | 50 | 54 | 6 | 11 |
| David Wells* | EDG | sp | 43 | 4.42 | 3 | 5 | 0 | 13 | 13 | 0 | 0 | 75.1 | 97 | 41 | 37 | 12 | 38 | 11 | 10 |
| Kip Wells |   | sp | 29 | 6.50 | 2 | 5 | 0 | 9 | 9 | 0 | 0 | 44.1 | 61 | 33 | 32 | 21 | 20 | 3 | 7 |
| Jake Westbrook | MID | sp | 28 | 4.17 | 15 | 10 | 0 | 32 | 32 | 3 | 2 | 211.1 | 247 | 106 | 98 | 55 | 109 | 15 | 35 |
| Dan Wheeler | Pal | mr | 28 | 2.52 | 3 | 5 | 9 | 75 | 0 | 0 | 0 | 71.1 | 58 | 22 | 20 | 24 | 68 | 5 | 3 |
| Rick White |   | mr | 37 | 5.15 | 4 | 1 | 1 | 64 | 0 | 0 | 0 | 64.2 | 72 | 44 | 37 | 20 | 40 | 8 | 10 |
| Bob Wickman | COP | cl | 37 | 2.67 | 1 | 6 | 33 | 57 | 0 | 0 | 0 | 54.0 | 53 | 22 | 16 | 13 | 42 | 2 | 3 |
| Dave Williams* |   | sp | 27 | 6.52 | 5 | 4 | 0 | 14 | 13 | 0 | 0 | 69.0 | 93 | 52 | 50 | 20 | 32 | 14 | 5 |
| Jerome Williams |   | mr | 24 | 7.30 | 0 | 2 | 0 | 5 | 2 | 0 | 0 | 12.1 | 15 | 12 | 10 | 11 | 5 | 2 | 2 |
| Todd Williams |   | mr | 35 | 4.74 | 2 | 4 | 1 | 62 | 0 | 0 | 0 | 57.0 | 76 | 36 | 30 | 19 | 24 | 8 | 13 |
| Woody Williams | MUL | sp | 39 | 3.65 | 12 | 5 | 0 | 25 | 24 | 0 | 0 | 145.1 | 152 | 68 | 59 | 35 | 72 | 21 | 12 |
| Scott Williamson |   | mr | 30 | 5.72 | 2 | 4 | 0 | 42 | 0 | 0 | 0 | 39.1 | 41 | 26 | 25 | 22 | 42 | 4 | 4 |
| Dontrelle Willis* | MAD | sp | 24 | 3.87 | 12 | 12 | 0 | 34 | 34 | 4 | 1 | 223.1 | 234 | 106 | 96 | 83 | 160 | 21 | 32 |
| Brian Wilson |   | mr | 24 | 5.40 | 2 | 3 | 1 | 31 | 0 | 0 | 0 | 30.0 | 32 | 19 | 18 | 21 | 23 | 1 | 2 |
| C.J. Wilson* | ROK | mr | 25 | 4.06 | 2 | 4 | 1 | 44 | 0 | 0 | 0 | 44.1 | 39 | 23 | 20 | 18 | 43 | 7 | 5 |
| Kris Wilson |   | mr | 29 | 8.64 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 8.1 | 14 | 8 | 8 | 4 | 6 | 4 | 1 |
| Jason Windsor |   | sp | 23 | 6.59 | 0 | 1 | 0 | 4 | 3 | 0 | 0 | 13.2 | 21 | 12 | 10 | 5 | 6 | 2 | 3 |
| Joe Winkelsas |   | mr | 32 | 7.71 | 0 | 1 | 0 | 7 | 0 | 0 | 0 | 7.0 | 9 | 7 | 6 | 6 | 4 | 1 | 2 |
| Matt Wise |   | mr | 30 | 3.86 | 5 | 6 | 0 | 40 | 0 | 0 | 0 | 44.1 | 45 | 24 | 19 | 14 | 27 | 6 | 7 |
| Jay Witasick |   | mr | 33 | 6.75 | 1 | 0 | 0 | 20 | 0 | 0 | 0 | 22.2 | 25 | 17 | 17 | 21 | 23 | 3 | 3 |
| Randy Wolf* |   | sp | 29 | 5.56 | 4 | 0 | 0 | 12 | 12 | 0 | 0 | 56.2 | 63 | 37 | 35 | 33 | 44 | 13 | 2 |
| Kerry Wood | MUL | sp | 29 | 4.12 | 1 | 2 | 0 | 4 | 4 | 0 | 0 | 19.2 | 19 | 13 | 9 | 8 | 13 | 5 | 1 |
| Mike Wood |   | mr | 26 | 5.71 | 3 | 3 | 0 | 23 | 7 | 0 | 0 | 64.2 | 86 | 51 | 41 | 23 | 29 | 10 | 5 |
| Jake Woods* |   | mr | 24 | 4.20 | 7 | 4 | 1 | 37 | 8 | 0 | 0 | 105.0 | 115 | 51 | 49 | 53 | 66 | 12 | 10 |
| Tim Worrell |   | cl | 38 | 7.52 | 3 | 2 | 6 | 23 | 0 | 0 | 0 | 20.1 | 28 | 18 | 17 | 7 | 12 | 9 | 1 |
| Jamey Wright |   | sp | 31 | 5.19 | 6 | 10 | 0 | 34 | 21 | 0 | 0 | 156.0 | 167 | 95 | 90 | 64 | 79 | 16 | 24 |
| Jaret Wright |   | sp | 30 | 4.49 | 11 | 7 | 0 | 30 | 27 | 0 | 0 | 140.1 | 157 | 76 | 70 | 57 | 84 | 10 | 15 |
| Michael Wuertz | BT | mr | 27 | 2.66 | 3 | 1 | 0 | 41 | 0 | 0 | 0 | 40.2 | 35 | 14 | 12 | 16 | 42 | 5 | 1 |
| Esteban Yan |   | mr | 31 | 5.54 | 1 | 0 | 1 | 27 | 0 | 0 | 0 | 37.1 | 32 | 25 | 23 | 20 | 24 | 8 | 6 |
| Tyler Yates | TON | mr | 28 | 3.96 | 2 | 5 | 1 | 56 | 0 | 0 | 0 | 50.0 | 42 | 23 | 22 | 31 | 46 | 6 | 6 |
| Shane Youman* |   | sp | 26 | 2.91 | 0 | 2 | 0 | 5 | 3 | 0 | 0 | 21.2 | 15 | 7 | 7 | 10 | 5 | 1 | 2 |
| Chris Young | COP | sp | 27 | 3.46 | 11 | 5 | 0 | 31 | 31 | 0 | 0 | 179.1 | 134 | 72 | 69 | 69 | 164 | 28 | 8 |
| Carlos Zambrano | CCL | sp | 25 | 3.41 | 16 | 7 | 0 | 33 | 33 | 0 | 0 | 214.0 | 162 | 91 | 81 | 115 | 210 | 20 | 18 |
| Victor Zambrano |   | sp | 30 | 6.75 | 1 | 2 | 0 | 5 | 5 | 0 | 0 | 21.1 | 25 | 16 | 16 | 11 | 15 | 5 | 1 |
| Barry Zito* | EDG | sp | 28 | 3.83 | 16 | 10 | 0 | 34 | 34 | 0 | 0 | 221.0 | 211 | 99 | 94 | 99 | 151 | 27 | 31 |
| Joel Zumaya | ROK | mr | 21 | 1.94 | 6 | 3 | 1 | 62 | 0 | 0 | 0 | 83.1 | 56 | 20 | 18 | 42 | 97 | 6 | 1 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | CI | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | BT | mr | 24 | 5 | 0 | 0 | 1 | 1 | 0 | 1 | 3 | 0 | 7.0 | 4.8 | 11.9 | 8.3 | 1.5 | 1.8 | 1.30 |
| Winston Abreu |   | mr | 29 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 11.3 | 6.8 | 19.1 | 6.8 | 1.1 | 1.0 | 2.00 |
| Jeremy Accardo |   | mr | 24 | 6 | 1 | 5 | 1 | 4 | 1 | 1 | 4 | 0 | 9.9 | 2.6 | 12.7 | 7.0 | 0.9 | 2.7 | 1.39 |
| Mike Adams | MUL | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.4 | 7.7 | 23.1 | 3.9 | 3.9 | 0.5 | 2.57 |
| Jon Adkins |   | mr | 28 | 2 | 1 | 4 | 2 | 0 | 0 | 5 | 2 | 0 | 9.1 | 3.3 | 12.8 | 5.0 | 0.5 | 1.5 | 1.38 |
| Jeremy Affeldt* | CRH | mr | 27 | 8 | 0 | 3 | 2 | 2 | 0 | 4 | 4 | 0 | 9.4 | 5.1 | 14.7 | 4.4 | 1.2 | 0.9 | 1.61 |
| Matt Albers |   | sp | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 10.2 | 4.2 | 14.4 | 6.6 | 0.6 | 1.6 | 1.60 |
| Antonio Alfonseca |   | mr | 34 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 12.9 | 3.9 | 16.9 | 2.8 | 1.7 | 0.7 | 1.88 |
| Abe Alvarez* |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 6.0 | 21.0 | 6.0 | 6.0 | 1.0 | 2.33 |
| Steve Andrade |   | mr | 28 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 9.6 | 7.7 | 17.4 | 9.6 | 0.0 | 1.3 | 1.93 |
| Greg Aquino |   | mr | 28 | 3 | 1 | 2 | 4 | 2 | 0 | 1 | 0 | 0 | 10.1 | 4.5 | 15.3 | 9.5 | 1.5 | 2.1 | 1.61 |
| Tony Armas |   | sp | 28 | 11 | 2 | 7 | 13 | 6 | 1 | 12 | 6 | 0 | 9.8 | 3.7 | 14.3 | 5.7 | 1.1 | 1.5 | 1.50 |
| Bronson Arroyo | BT | sp | 29 | 5 | 5 | 7 | 5 | 6 | 0 | 9 | 2 | 0 | 8.3 | 2.4 | 10.9 | 6.9 | 1.2 | 2.9 | 1.19 |
| Miguel Asencio |   | mr | 25 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 10.6 | 4.7 | 16.4 | 8.2 | 1.2 | 1.8 | 1.70 |
| Ezequiel Astacio |   | mr | 26 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 11.1 | 9.5 | 20.6 | 9.5 | 3.2 | 1.0 | 2.29 |
| Pedro Astacio |   | sp | 36 | 4 | 1 | 3 | 1 | 0 | 1 | 8 | 5 | 0 | 10.9 | 3.1 | 14.0 | 4.2 | 1.4 | 1.4 | 1.55 |
| Brandon Backe |   | sp | 28 | 0 | 1 | 0 | 3 | 2 | 0 | 1 | 2 | 0 | 9.0 | 3.8 | 13.4 | 4.0 | 0.8 | 1.1 | 1.42 |
| Cha Seung Baek |   | sp | 26 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.8 | 3.4 | 10.7 | 6.0 | 1.6 | 1.8 | 1.14 |
| Danys Baez |   | mr | 28 | 5 | 2 | 3 | 7 | 3 | 0 | 4 | 5 | 0 | 9.1 | 2.6 | 12.7 | 5.9 | 0.5 | 2.3 | 1.29 |
| Jeff Bajenaru |   | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 36.0 | 0.0 | 36.0 | 0.0 | 27.0 | 0.0 | 4.00 |
| Scott Baker |   | sp | 24 | 5 | 3 | 1 | 3 | 0 | 0 | 2 | 4 | 0 | 12.3 | 1.7 | 14.4 | 6.7 | 1.8 | 3.9 | 1.56 |
| Brian Bannister |   | sp | 25 | 7 | 1 | 2 | 2 | 2 | 0 | 1 | 4 | 0 | 8.1 | 5.2 | 13.7 | 4.5 | 0.9 | 0.9 | 1.47 |
| Kevin Barry |   | mr | 27 | 5 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 0 | 8.4 | 4.9 | 13.7 | 6.7 | 0.7 | 1.4 | 1.48 |
| Phil Barzilla* |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Miguel Batista |   | sp | 35 | 15 | 7 | 5 | 6 | 14 | 1 | 12 | 5 | 0 | 10.1 | 3.7 | 14.0 | 4.8 | 0.8 | 1.3 | 1.53 |
| Rick Bauer | EDG | mr | 29 | 4 | 2 | 0 | 4 | 3 | 0 | 0 | 5 | 0 | 9.3 | 3.2 | 12.9 | 4.4 | 0.5 | 1.4 | 1.38 |
| Denny Bautista |   | sp | 23 | 2 | 2 | 0 | 4 | 5 | 0 | 1 | 2 | 0 | 10.2 | 4.5 | 15.6 | 5.8 | 1.1 | 1.3 | 1.63 |
| Jonah Bayliss |   | mr | 25 | 2 | 0 | 2 | 1 | 2 | 0 | 2 | 1 | 0 | 8.0 | 6.8 | 15.3 | 9.2 | 0.6 | 1.4 | 1.64 |
| T.J. Beam |   | mr | 25 | 1 | 0 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 13.0 | 3.0 | 17.0 | 6.0 | 2.5 | 2.0 | 1.78 |
| Colter Bean |   | mr | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 9.0 | 9.0 | 22.5 | 4.5 | 0.0 | 0.5 | 2.00 |
| Josh Beckett | Pal | sp | 26 | 15 | 1 | 1 | 10 | 11 | 1 | 2 | 3 | 0 | 8.4 | 3.3 | 12.1 | 6.9 | 1.6 | 2.1 | 1.29 |
| Erik Bedard* | GEO | sp | 27 | 4 | 2 | 0 | 5 | 6 | 0 | 6 | 4 | 0 | 9.0 | 3.2 | 12.4 | 7.8 | 0.7 | 2.5 | 1.35 |
| Joe Beimel* |   | mr | 29 | 3 | 4 | 3 | 0 | 6 | 1 | 4 | 3 | 0 | 9.0 | 2.7 | 11.7 | 3.9 | 0.9 | 1.4 | 1.30 |
| Matt Belisle |   | mr | 26 | 1 | 0 | 1 | 3 | 3 | 0 | 1 | 2 | 0 | 9.7 | 4.3 | 14.6 | 5.8 | 1.1 | 1.4 | 1.55 |
| Heath Bell | MUL | mr | 28 | 2 | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 12.4 | 2.7 | 15.1 | 8.5 | 1.5 | 3.2 | 1.68 |
| Armando Benitez |   | cl | 33 | 6 | 0 | 2 | 0 | 1 | 0 | 1 | 3 | 0 | 9.2 | 4.9 | 14.1 | 7.3 | 1.4 | 1.5 | 1.57 |
| Joaquin Benoit | OTR | mr | 28 | 1 | 0 | 4 | 3 | 3 | 0 | 0 | 3 | 0 | 7.7 | 4.3 | 12.3 | 9.6 | 0.6 | 2.2 | 1.33 |
| Kris Benson |   | sp | 31 | 12 | 6 | 2 | 7 | 6 | 0 | 9 | 13 | 0 | 9.8 | 2.9 | 13.0 | 4.3 | 1.6 | 1.5 | 1.40 |
| Jason Bergmann |   | mr | 24 | 1 | 1 | 6 | 6 | 3 | 0 | 6 | 4 | 0 | 11.3 | 3.8 | 15.9 | 7.5 | 1.7 | 2.0 | 1.67 |
| Adam Bernero |   | sp | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.2 | 1.2 | 14.4 | 7.2 | 1.8 | 6.0 | 1.60 |
| Rafael Betancourt | GEO | mr | 31 | 8 | 2 | 5 | 0 | 0 | 0 | 2 | 2 | 0 | 8.3 | 1.7 | 10.0 | 7.6 | 1.1 | 4.4 | 1.11 |
| Chad Billingsley | TON | sp | 21 | 5 | 5 | 3 | 3 | 5 | 0 | 4 | 0 | 0 | 9.2 | 5.8 | 15.3 | 5.9 | 0.7 | 1.0 | 1.67 |
| Kurt Birkins* |   | mr | 25 | 0 | 1 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 7.3 | 4.6 | 12.8 | 7.8 | 1.2 | 1.7 | 1.32 |
| Joe Blanton | BON | sp | 25 | 13 | 5 | 4 | 5 | 3 | 0 | 3 | 9 | 0 | 11.2 | 2.7 | 14.1 | 5.0 | 0.8 | 1.8 | 1.54 |
| Jeremy Bonderman | OTR | sp | 23 | 14 | 2 | 7 | 3 | 3 | 1 | 3 | 6 | 0 | 9.0 | 2.7 | 11.8 | 8.5 | 0.8 | 3.2 | 1.30 |
| Boof Bonser | BON | sp | 24 | 4 | 3 | 0 | 1 | 2 | 0 | 2 | 2 | 0 | 9.3 | 2.2 | 11.6 | 7.5 | 1.6 | 3.5 | 1.28 |
| Chris Booker |   | mr | 29 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.8 | 4.3 | 15.1 | 7.6 | 4.3 | 1.8 | 1.68 |
| Chris Bootcheck |   | mr | 27 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 13.9 | 7.8 | 21.8 | 6.1 | 2.6 | 0.8 | 2.42 |
| Dave Borkowski |   | mr | 29 | 1 | 0 | 7 | 0 | 2 | 0 | 2 | 2 | 0 | 8.9 | 2.9 | 11.8 | 6.6 | 1.0 | 2.3 | 1.31 |
| Joe Borowski |   | cl | 35 | 4 | 1 | 7 | 2 | 1 | 0 | 1 | 0 | 0 | 8.1 | 4.3 | 12.7 | 8.3 | 0.9 | 1.9 | 1.38 |
| Micah Bowie* |   | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.0 | 3.2 | 8.2 | 5.0 | 0.5 | 1.6 | 0.92 |
| Blaine Boyer |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 54.0 | 13.5 | 67.5 | 0.0 | 0.0 | 0.0 | 7.50 |
| Chad Bradford | EDG | mr | 31 | 3 | 0 | 4 | 0 | 0 | 0 | 4 | 3 | 0 | 8.6 | 1.9 | 10.5 | 6.5 | 0.1 | 3.5 | 1.16 |
| Ryan Braun |   | mr | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 11.0 | 2.5 | 13.5 | 5.1 | 1.7 | 2.0 | 1.50 |
| Bill Bray* |   | mr | 23 | 1 | 1 | 3 | 1 | 0 | 0 | 2 | 1 | 0 | 10.1 | 3.2 | 13.5 | 6.9 | 0.9 | 2.2 | 1.48 |
| Dewon Brazelton |   | mr | 26 | 3 | 0 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 14.0 | 4.5 | 18.5 | 4.5 | 3.0 | 1.0 | 2.06 |
| Yhency Brazoban |   | mr | 26 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 12.6 | 3.6 | 16.2 | 7.2 | 0.0 | 2.0 | 1.80 |
| Craig Breslow* |   | mr | 25 | 2 | 0 | 1 | 1 | 2 | 1 | 0 | 2 | 0 | 9.0 | 4.5 | 14.3 | 9.0 | 0.0 | 2.0 | 1.50 |
| Eude Brito* |   | mr | 27 | 1 | 0 | 2 | 1 | 3 | 1 | 2 | 1 | 0 | 10.3 | 5.9 | 16.7 | 4.4 | 1.0 | 0.8 | 1.80 |
| Chris Britton | OTR | mr | 23 | 6 | 1 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 7.7 | 2.9 | 10.6 | 6.9 | 0.7 | 2.4 | 1.17 |
| Doug Brocail |   | mr | 39 | 1 | 0 | 2 | 0 | 1 | 0 | 3 | 1 | 0 | 8.6 | 2.5 | 11.1 | 6.0 | 0.3 | 2.4 | 1.24 |
| Jim Brower |   | mr | 33 | 1 | 1 | 1 | 5 | 2 | 0 | 0 | 1 | 0 | 14.4 | 6.3 | 22.9 | 6.3 | 0.9 | 1.0 | 2.30 |
| Andrew Brown |   | mr | 25 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 5.4 | 7.2 | 13.5 | 6.3 | 0.0 | 0.9 | 1.40 |
| Jonathan Broxton | CCL | mr | 22 | 5 | 2 | 6 | 1 | 7 | 0 | 3 | 1 | 0 | 7.2 | 3.9 | 11.2 | 11.4 | 0.8 | 2.9 | 1.23 |
| Brian Bruney |   | mr | 24 | 1 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 6.1 | 6.5 | 13.1 | 10.9 | 0.4 | 1.7 | 1.40 |
| Taylor Buchholz | MUL | sp | 24 | 11 | 1 | 4 | 3 | 5 | 0 | 5 | 6 | 0 | 8.5 | 2.7 | 11.5 | 6.1 | 1.7 | 2.3 | 1.25 |
| Mark Buehrle* | GEO | sp | 27 | 4 | 7 | 5 | 6 | 0 | 1 | 6 | 7 | 0 | 10.9 | 2.1 | 13.3 | 4.3 | 1.6 | 2.0 | 1.45 |
| Jason Bulger |   | mr | 27 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.4 | 16.2 | 21.6 | 5.4 | 0.0 | 0.3 | 2.40 |
| Ambiorix Burgos |   | cl | 22 | 5 | 0 | 4 | 6 | 11 | 3 | 1 | 4 | 0 | 10.2 | 4.5 | 15.5 | 8.8 | 2.0 | 1.9 | 1.64 |
| A.J. Burnett | TON | sp | 29 | 18 | 4 | 3 | 8 | 6 | 1 | 4 | 3 | 0 | 9.2 | 2.6 | 12.3 | 7.8 | 0.9 | 3.0 | 1.30 |
| Mike Burns |   | mr | 27 | 0 | 1 | 2 | 2 | 1 | 0 | 1 | 2 | 0 | 17.1 | 1.7 | 19.7 | 6.9 | 0.9 | 4.0 | 2.10 |
| Brian Burres* |   | mr | 25 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 1.1 | 7.9 | 6.8 | 1.1 | 6.0 | 0.88 |
| Dave Bush | OTR | sp | 26 | 18 | 8 | 2 | 18 | 6 | 0 | 9 | 6 | 0 | 8.6 | 1.6 | 11.0 | 7.1 | 1.1 | 4.4 | 1.14 |
| Paul Byrd |   | sp | 35 | 18 | 5 | 3 | 6 | 2 | 0 | 1 | 6 | 0 | 11.7 | 1.9 | 13.9 | 4.4 | 1.3 | 2.3 | 1.51 |
| Tim Byrdak* |   | mr | 32 | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 18.0 | 10.3 | 28.3 | 2.6 | 2.6 | 0.3 | 3.14 |
| Daniel Cabrera | CRH | sp | 25 | 11 | 5 | 1 | 5 | 17 | 1 | 5 | 8 | 0 | 7.9 | 6.3 | 14.5 | 9.5 | 0.7 | 1.5 | 1.58 |
| Fernando Cabrera |   | mr | 24 | 11 | 6 | 2 | 1 | 5 | 0 | 1 | 4 | 0 | 7.9 | 4.7 | 12.8 | 10.5 | 1.8 | 2.2 | 1.40 |
| Matt Cain | LON | sp | 21 | 15 | 3 | 1 | 6 | 9 | 2 | 11 | 6 | 0 | 7.4 | 4.1 | 11.8 | 8.4 | 0.8 | 2.1 | 1.28 |
| Kiko Calero | LON | mr | 31 | 6 | 3 | 3 | 0 | 1 | 0 | 0 | 1 | 0 | 7.8 | 3.7 | 11.5 | 10.4 | 0.6 | 2.8 | 1.28 |
| Shawn Camp |   | mr | 30 | 6 | 2 | 3 | 7 | 4 | 0 | 2 | 3 | 0 | 11.2 | 2.3 | 14.3 | 6.4 | 1.1 | 2.8 | 1.49 |
| Brett Campbell |   | mr | 24 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.3 | 4.2 | 14.5 | 8.3 | 2.1 | 2.0 | 1.38 |
| Jorge Campillo |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.4 | 0.0 | 15.4 | 3.9 | 0.0 | 99.0 | 1.71 |
| Jose Capellan |   | mr | 25 | 10 | 3 | 7 | 3 | 3 | 0 | 8 | 2 | 0 | 8.2 | 3.9 | 12.4 | 7.3 | 1.4 | 1.9 | 1.34 |
| Matt Capps | MUL | mr | 22 | 3 | 3 | 5 | 3 | 4 | 0 | 8 | 2 | 0 | 9.0 | 1.3 | 10.7 | 6.2 | 1.3 | 4.7 | 1.15 |
| Chris Capuano* | BT | sp | 27 | 1 | 3 | 4 | 9 | 7 | 0 | 9 | 8 | 0 | 9.3 | 1.9 | 11.6 | 7.1 | 1.2 | 3.7 | 1.25 |
| Fausto Carmona | GEO | mr | 22 | 10 | 2 | 3 | 7 | 3 | 1 | 2 | 4 | 1 | 10.6 | 3.7 | 15.2 | 7.0 | 1.1 | 1.9 | 1.59 |
| Chris Carpenter | CRH | sp | 31 | 3 | 7 | 3 | 10 | 3 | 0 | 12 | 4 | 0 | 7.9 | 1.7 | 10.0 | 7.5 | 0.9 | 4.3 | 1.07 |
| Giovanni Carrara |   | mr | 38 | 4 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 8.8 | 2.3 | 11.4 | 8.1 | 1.6 | 3.6 | 1.23 |
| Hector Carrasco | LON | mr | 36 | 2 | 0 | 1 | 5 | 6 | 0 | 2 | 2 | 0 | 8.3 | 2.4 | 11.2 | 6.5 | 0.9 | 2.7 | 1.20 |
| Lance Carter |   | mr | 31 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 13.1 | 6.2 | 19.3 | 3.9 | 0.8 | 0.6 | 2.14 |
| Santiago Casilla |   | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 7.7 | 15.4 | 7.7 | 0.0 | 1.0 | 1.71 |
| Scott Cassidy |   | mr | 30 | 1 | 4 | 2 | 1 | 0 | 0 | 4 | 1 | 0 | 8.2 | 4.0 | 12.4 | 10.3 | 1.7 | 2.6 | 1.36 |
| Fabio Castro* |   | mr | 21 | 1 | 0 | 0 | 2 | 0 | 1 | 2 | 2 | 0 | 5.1 | 3.7 | 9.4 | 5.1 | 0.3 | 1.4 | 0.98 |
| Gustavo Chacin* |   | sp | 25 | 5 | 0 | 2 | 6 | 0 | 0 | 2 | 0 | 0 | 9.3 | 3.9 | 13.8 | 4.8 | 2.0 | 1.2 | 1.47 |
| Shawn Chacon |   | sp | 28 | 9 | 2 | 3 | 9 | 4 | 1 | 7 | 7 | 0 | 10.2 | 5.2 | 16.2 | 5.1 | 1.9 | 1.0 | 1.72 |
| Bruce Chen* |   | mr | 29 | 9 | 6 | 3 | 0 | 1 | 0 | 3 | 5 | 0 | 12.5 | 3.2 | 15.7 | 6.4 | 2.6 | 2.0 | 1.74 |
| Travis Chick |   | mr | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.6 | 18.0 | 30.6 | 3.6 | 0.0 | 0.2 | 3.40 |
| Jason Childers |   | mr | 31 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 14.1 | 4.7 | 18.8 | 5.9 | 1.2 | 1.3 | 2.09 |
| Randy Choate* |   | mr | 30 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 11.8 | 1.7 | 15.2 | 6.8 | 0.0 | 4.0 | 1.50 |
| Vinnie Chulk |   | mr | 27 | 1 | 0 | 2 | 3 | 4 | 0 | 0 | 2 | 0 | 8.9 | 3.9 | 13.4 | 8.4 | 1.2 | 2.2 | 1.42 |
| Brandon Claussen* |   | sp | 27 | 7 | 3 | 1 | 6 | 2 | 0 | 6 | 2 | 0 | 10.9 | 3.3 | 14.8 | 6.7 | 1.6 | 2.0 | 1.57 |
| Roger Clemens | ROK | sp | 43 | 14 | 2 | 1 | 4 | 3 | 0 | 5 | 1 | 0 | 7.1 | 2.3 | 9.7 | 8.1 | 0.6 | 3.5 | 1.04 |
| Matt Clement |   | sp | 31 | 1 | 1 | 0 | 6 | 3 | 0 | 1 | 0 | 0 | 10.6 | 5.2 | 16.7 | 5.9 | 1.1 | 1.1 | 1.76 |
| Todd Coffey |   | mr | 25 | 0 | 2 | 5 | 2 | 4 | 0 | 0 | 1 | 0 | 9.8 | 3.1 | 13.2 | 6.9 | 0.8 | 2.2 | 1.44 |
| Jesus Colome |   | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 27.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Bartolo Colon |   | sp | 33 | 1 | 3 | 0 | 3 | 1 | 0 | 4 | 1 | 0 | 11.3 | 1.8 | 13.6 | 5.0 | 1.8 | 2.8 | 1.46 |
| Roman Colon |   | mr | 26 | 0 | 2 | 2 | 1 | 6 | 0 | 1 | 2 | 0 | 10.7 | 3.3 | 14.2 | 5.8 | 1.4 | 1.8 | 1.55 |
| Clay Condrey |   | mr | 30 | 1 | 1 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 11.0 | 2.8 | 13.8 | 5.0 | 0.9 | 1.8 | 1.53 |
| Jose Contreras | GEO | sp | 34 | 21 | 6 | 4 | 10 | 16 | 0 | 2 | 8 | 0 | 8.9 | 2.5 | 11.9 | 6.2 | 0.9 | 2.4 | 1.27 |
| Aaron Cook | MAD | sp | 27 | 7 | 5 | 11 | 7 | 2 | 0 | 8 | 5 | 0 | 10.2 | 2.3 | 12.9 | 3.9 | 0.7 | 1.7 | 1.40 |
| Roy Corcoran |   | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 19.1 | 6.4 | 25.4 | 9.5 | 1.6 | 1.5 | 2.82 |
| Tim Corcoran |   | sp | 28 | 10 | 6 | 3 | 4 | 0 | 1 | 1 | 4 | 0 | 9.2 | 4.8 | 14.3 | 5.9 | 1.0 | 1.2 | 1.55 |
| Chad Cordero |   | cl | 24 | 3 | 1 | 5 | 3 | 0 | 0 | 6 | 2 | 0 | 7.2 | 2.7 | 10.3 | 8.5 | 1.6 | 3.1 | 1.10 |
| Francisco Cordero | CRH | cl | 31 | 4 | 2 | 2 | 3 | 4 | 0 | 3 | 5 | 0 | 8.2 | 3.8 | 12.4 | 10.0 | 0.8 | 2.6 | 1.34 |
| Bryan Corey |   | mr | 32 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 3 | 0 | 8.1 | 3.5 | 12.0 | 6.5 | 0.2 | 1.9 | 1.28 |
| Lance Cormier |   | mr | 25 | 5 | 3 | 7 | 2 | 2 | 0 | 1 | 4 | 0 | 11.0 | 4.8 | 16.0 | 5.3 | 1.0 | 1.1 | 1.75 |
| Rheal Cormier* |   | mr | 39 | 1 | 0 | 3 | 3 | 2 | 0 | 5 | 0 | 0 | 9.0 | 3.2 | 12.8 | 3.6 | 0.9 | 1.1 | 1.35 |
| Manuel Corpas |   | mr | 23 | 3 | 1 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 10.0 | 2.2 | 12.8 | 7.5 | 0.8 | 3.4 | 1.36 |
| Kevin Correia | MUL | mr | 25 | 3 | 3 | 0 | 3 | 0 | 0 | 1 | 4 | 0 | 8.3 | 2.8 | 11.5 | 7.4 | 0.6 | 2.6 | 1.23 |
| David Cortes |   | mr | 32 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 0 | 10.7 | 1.8 | 12.9 | 4.3 | 0.9 | 2.3 | 1.40 |
| Neal Cotts* |   | mr | 26 | 2 | 0 | 6 | 3 | 3 | 0 | 3 | 1 | 0 | 10.7 | 4.0 | 15.2 | 7.2 | 2.0 | 1.8 | 1.63 |
| Jesse Crain | GEO | mr | 24 | 4 | 1 | 2 | 2 | 1 | 0 | 1 | 2 | 0 | 9.3 | 2.1 | 11.6 | 7.0 | 0.7 | 3.3 | 1.27 |
| Francisco Cruceta |   | mr | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 13.5 | 8.1 | 21.6 | 2.7 | 2.7 | 0.3 | 2.40 |
| Juan Cruz | TON | mr | 27 | 7 | 3 | 2 | 11 | 2 | 0 | 5 | 2 | 0 | 7.6 | 4.5 | 13.1 | 8.4 | 0.7 | 1.9 | 1.34 |
| Casey Daigle |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 10.2 | 4.4 | 14.6 | 5.1 | 0.7 | 1.2 | 1.62 |
| Kyle Davies |   | sp | 22 | 4 | 1 | 0 | 3 | 3 | 0 | 3 | 2 | 0 | 12.8 | 4.7 | 17.9 | 7.2 | 2.0 | 1.5 | 1.94 |
| Doug Davis* |   | sp | 30 | 15 | 4 | 1 | 5 | 3 | 0 | 16 | 8 | 0 | 9.1 | 4.5 | 13.9 | 7.0 | 0.8 | 1.6 | 1.51 |
| Jason Davis |   | mr | 26 | 4 | 1 | 2 | 3 | 3 | 0 | 3 | 4 | 0 | 10.9 | 2.3 | 13.7 | 6.0 | 0.2 | 2.6 | 1.46 |
| Zach Day |   | sp | 28 | 9 | 1 | 2 | 3 | 1 | 0 | 1 | 1 | 0 | 11.5 | 4.7 | 16.9 | 4.3 | 1.1 | 0.9 | 1.80 |
| Jorge De La Rosa* |   | mr | 25 | 10 | 1 | 1 | 2 | 6 | 1 | 2 | 4 | 0 | 9.2 | 6.2 | 15.6 | 7.6 | 1.6 | 1.2 | 1.71 |
| Mike DeJean |   | mr | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 10.8 | 16.2 | 0.0 | 0.0 | 0.0 | 1.80 |
| Manny Delcarmen |   | mr | 24 | 5 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 0 | 11.5 | 2.9 | 14.7 | 7.6 | 0.3 | 2.6 | 1.59 |
| Chris Demaria |   | mr | 25 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 6.6 | 5.9 | 13.8 | 7.2 | 2.6 | 1.2 | 1.39 |
| Ryan Dempster | CRH | cl | 29 | 5 | 0 | 3 | 3 | 6 | 0 | 5 | 4 | 0 | 9.2 | 4.3 | 13.9 | 8.0 | 0.6 | 1.9 | 1.51 |
| Elmer Dessens |   | mr | 35 | 3 | 2 | 8 | 1 | 3 | 0 | 5 | 1 | 0 | 10.1 | 2.6 | 12.7 | 6.1 | 0.9 | 2.4 | 1.40 |
| Joey Devine |   | mr | 22 | 0 | 0 | 1 | 1 | 4 | 1 | 0 | 0 | 0 | 11.4 | 12.8 | 25.6 | 14.2 | 1.4 | 1.1 | 2.68 |
| Jose Diaz |   | mr | 22 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 13.5 | 10.8 | 25.6 | 4.0 | 2.7 | 0.4 | 2.70 |
| R.A. Dickey | OTR | sp | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 21.6 | 2.7 | 24.3 | 2.7 | 16.2 | 1.0 | 2.70 |
| Lenny DiNardo* |   | mr | 26 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 14.1 | 4.6 | 18.9 | 3.9 | 1.4 | 0.9 | 2.08 |
| Scott Dohmann |   | mr | 28 | 4 | 1 | 7 | 4 | 5 | 0 | 4 | 0 | 1 | 11.0 | 6.1 | 17.9 | 8.2 | 1.7 | 1.3 | 1.90 |
| Brendan Donnelly | CRH | mr | 34 | 1 | 0 | 3 | 4 | 6 | 0 | 2 | 2 | 0 | 8.2 | 3.9 | 12.7 | 7.5 | 1.1 | 1.9 | 1.34 |
| Octavio Dotel |   | mr | 32 | 1 | 0 | 1 | 0 | 3 | 0 | 0 | 1 | 0 | 16.2 | 9.9 | 26.1 | 6.3 | 1.8 | 0.6 | 2.90 |
| Scott Downs* | EDG | mr | 30 | 1 | 1 | 6 | 2 | 7 | 0 | 1 | 1 | 0 | 8.5 | 3.5 | 12.3 | 7.1 | 1.1 | 2.0 | 1.34 |
| Ryan Drese |   | sp | 30 | 1 | 2 | 0 | 0 | 2 | 0 | 2 | 0 | 0 | 9.3 | 8.3 | 17.7 | 5.2 | 0.0 | 0.6 | 1.96 |
| Eric DuBose* |   | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.3 | 5.8 | 25.1 | 3.9 | 3.9 | 0.7 | 2.79 |
| Justin Duchscherer | COP | mr | 28 | 5 | 1 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 8.4 | 1.5 | 10.0 | 8.2 | 0.6 | 5.7 | 1.10 |
| Brandon Duckworth |   | sp | 30 | 0 | 1 | 4 | 2 | 4 | 0 | 1 | 2 | 0 | 12.2 | 4.7 | 17.3 | 5.3 | 0.6 | 1.1 | 1.88 |
| Zach Duke* |   | sp | 23 | 13 | 12 | 6 | 7 | 8 | 1 | 13 | 4 | 0 | 10.7 | 2.8 | 13.8 | 4.9 | 0.7 | 1.7 | 1.50 |
| Scott Dunn |   | mr | 28 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 20.0 | 4.7 | 27.0 | 4.7 | 2.3 | 1.0 | 2.74 |
| Chad Durbin |   | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 4.5 | 1.5 | 99.0 | 1.00 |
| Adam Eaton |   | sp | 28 | 2 | 5 | 0 | 4 | 0 | 0 | 1 | 1 | 0 | 10.8 | 3.3 | 14.7 | 6.0 | 1.5 | 1.8 | 1.57 |
| Joey Eischen* |   | mr | 36 | 3 | 0 | 5 | 1 | 1 | 0 | 0 | 2 | 0 | 11.0 | 11.7 | 23.3 | 11.0 | 1.2 | 0.9 | 2.52 |
| Scott Elarton |   | sp | 30 | 4 | 3 | 1 | 6 | 3 | 0 | 2 | 2 | 0 | 9.2 | 4.1 | 13.7 | 3.8 | 2.0 | 0.9 | 1.47 |
| Alan Embree* | LON | mr | 36 | 12 | 1 | 2 | 0 | 0 | 0 | 2 | 3 | 0 | 8.6 | 2.6 | 11.2 | 9.1 | 0.7 | 3.5 | 1.24 |
| Scott Erickson |   | mr | 38 | 2 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 0 | 10.3 | 5.6 | 18.3 | 1.6 | 1.6 | 0.3 | 1.76 |
| Kelvim Escobar | COP | sp | 30 | 14 | 10 | 2 | 4 | 7 | 0 | 6 | 3 | 0 | 9.1 | 2.4 | 11.7 | 7.0 | 0.8 | 2.9 | 1.28 |
| Shawn Estes* |   | sp | 33 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.5 | 4.5 | 13.5 | 6.0 | 0.0 | 1.3 | 1.33 |
| Seth Etherton |   | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 11.7 | 7.0 | 18.8 | 4.7 | 3.5 | 0.7 | 2.09 |
| Dana Eveland* |   | sp | 22 | 5 | 2 | 2 | 5 | 2 | 0 | 1 | 1 | 0 | 12.7 | 5.2 | 19.5 | 10.4 | 1.3 | 2.0 | 1.99 |
| Scott Eyre* |   | mr | 34 | 4 | 1 | 4 | 0 | 6 | 0 | 2 | 4 | 0 | 9.0 | 4.4 | 13.4 | 10.7 | 1.6 | 2.4 | 1.48 |
| Willie Eyre |   | mr | 27 | 1 | 1 | 4 | 6 | 4 | 0 | 1 | 3 | 0 | 11.4 | 3.3 | 15.6 | 3.9 | 1.2 | 1.2 | 1.63 |
| Brian Falkenborg |   | mr | 28 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 7.1 | 0.0 | 8.5 | 7.1 | 0.0 | 99.0 | 0.79 |
| Kyle Farnsworth | BON | mr | 30 | 6 | 2 | 3 | 1 | 5 | 1 | 3 | 2 | 0 | 8.5 | 3.8 | 12.4 | 10.2 | 1.1 | 2.7 | 1.36 |
| Jeff Fassero* |   | mr | 43 | 0 | 1 | 0 | 0 | 2 | 0 | 1 | 1 | 0 | 13.8 | 4.8 | 18.6 | 4.2 | 2.4 | 0.9 | 2.07 |
| Ryan Feierabend* |   | sp | 20 | 0 | 1 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 7.9 | 3.7 | 11.6 | 5.8 | 1.6 | 1.6 | 1.29 |
| Scott Feldman | MID | mr | 23 | 2 | 1 | 0 | 4 | 0 | 0 | 2 | 1 | 0 | 9.1 | 2.2 | 12.2 | 6.5 | 0.9 | 3.0 | 1.26 |
| Pedro Feliciano* | MAD | mr | 29 | 0 | 1 | 1 | 3 | 1 | 0 | 4 | 3 | 0 | 8.4 | 3.0 | 11.8 | 8.1 | 0.6 | 2.7 | 1.26 |
| Jared Fernandez |   | mr | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.6 | 1.4 | 17.1 | 1.4 | 2.8 | 1.0 | 1.89 |
| Nate Field |   | mr | 30 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 5.0 | 14.0 | 14.0 | 2.0 | 2.8 | 1.56 |
| Randy Flores* |   | mr | 30 | 1 | 2 | 3 | 1 | 1 | 0 | 3 | 1 | 0 | 10.6 | 4.8 | 15.6 | 8.6 | 1.1 | 1.8 | 1.70 |
| Ron Flores* |   | mr | 26 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 2 | 0 | 8.5 | 3.0 | 11.5 | 6.1 | 0.9 | 2.0 | 1.28 |
| Gavin Floyd | TON | sp | 23 | 11 | 2 | 3 | 3 | 2 | 0 | 2 | 5 | 0 | 11.6 | 5.3 | 17.4 | 5.6 | 2.3 | 1.1 | 1.88 |
| Josh Fogg |   | sp | 29 | 8 | 6 | 13 | 6 | 3 | 0 | 6 | 5 | 1 | 10.8 | 3.1 | 14.2 | 4.9 | 1.3 | 1.5 | 1.55 |
| Bartolome Fortunato |   | mr | 31 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 21.0 | 6.0 | 30.0 | 0.0 | 6.0 | 0.0 | 3.00 |
| Casey Fossum* |   | sp | 28 | 12 | 3 | 3 | 12 | 4 | 1 | 2 | 3 | 0 | 9.4 | 4.4 | 14.6 | 6.1 | 1.2 | 1.4 | 1.53 |
| Keith Foulke |   | mr | 33 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 4 | 0 | 9.4 | 1.3 | 11.1 | 6.5 | 1.6 | 5.1 | 1.19 |
| Jeff Francis* | MAD | sp | 25 | 21 | 7 | 15 | 13 | 0 | 0 | 7 | 7 | 0 | 8.5 | 3.1 | 12.2 | 5.3 | 0.8 | 1.7 | 1.29 |
| Frank Francisco |   | mr | 26 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.8 | 2.5 | 12.3 | 7.4 | 2.5 | 3.0 | 1.36 |
| Ryan Franklin |   | mr | 33 | 4 | 3 | 10 | 4 | 2 | 0 | 2 | 2 | 0 | 10.0 | 3.8 | 14.3 | 5.0 | 1.5 | 1.3 | 1.54 |
| Wayne Franklin* |   | mr | 32 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 9.4 | 7.0 | 16.4 | 3.5 | 2.3 | 0.5 | 1.83 |
| Jason Frasor | MID | mr | 28 | 4 | 1 | 1 | 2 | 3 | 0 | 0 | 3 | 0 | 8.5 | 3.1 | 11.9 | 9.2 | 1.4 | 3.0 | 1.28 |
| Emiliano Fruto |   | mr | 22 | 3 | 0 | 1 | 2 | 4 | 0 | 0 | 1 | 0 | 8.5 | 6.0 | 15.0 | 8.5 | 1.0 | 1.4 | 1.61 |
| Brian Fuentes* | CCL | cl | 30 | 3 | 1 | 4 | 6 | 6 | 0 | 2 | 1 | 0 | 6.9 | 3.6 | 11.3 | 10.1 | 1.1 | 2.8 | 1.16 |
| Jeff Fulchino |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 27.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Aaron Fultz* | MAD | mr | 32 | 5 | 2 | 8 | 2 | 5 | 0 | 3 | 6 | 0 | 10.1 | 3.5 | 13.9 | 7.8 | 0.9 | 2.2 | 1.51 |
| Kason Gabbard* |   | sp | 24 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 8.4 | 5.6 | 14.0 | 5.3 | 0.0 | 0.9 | 1.56 |
| Eric Gagne |   | cl | 30 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 4.5 | 9.0 | 13.5 | 0.0 | 3.0 | 0.50 |
| Mike Gallo* |   | mr | 28 | 1 | 0 | 1 | 2 | 4 | 0 | 2 | 1 | 0 | 15.4 | 3.9 | 20.4 | 3.9 | 1.7 | 1.0 | 2.14 |
| Freddy Garcia | EDG | sp | 30 | 40 | 2 | 3 | 7 | 4 | 0 | 1 | 6 | 0 | 9.5 | 2.0 | 11.8 | 5.6 | 1.3 | 2.8 | 1.28 |
| Jose Garcia |   | mr | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.2 | 4.1 | 12.3 | 6.5 | 0.8 | 1.6 | 1.36 |
| Jon Garland | COP | sp | 26 | 6 | 7 | 4 | 6 | 4 | 0 | 5 | 8 | 0 | 10.5 | 1.7 | 12.5 | 4.8 | 1.1 | 2.7 | 1.36 |
| Matt Garza | GEO | sp | 22 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 11.2 | 4.1 | 15.3 | 6.8 | 1.1 | 1.7 | 1.70 |
| Chad Gaudin |   | mr | 23 | 6 | 0 | 2 | 1 | 2 | 2 | 0 | 3 | 0 | 7.2 | 5.9 | 13.2 | 5.1 | 0.4 | 0.9 | 1.45 |
| Geoff Geary |   | mr | 29 | 4 | 2 | 4 | 6 | 2 | 0 | 3 | 1 | 1 | 10.1 | 2.0 | 12.7 | 5.9 | 0.6 | 3.0 | 1.35 |
| Franklyn German |   | mr | 26 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 5.3 | 10.5 | 16.5 | 4.5 | 0.8 | 0.4 | 1.75 |
| Justin Germano |   | sp | 23 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 10.8 | 4.0 | 16.2 | 10.8 | 1.3 | 2.7 | 1.65 |
| Tom Glavine* | WIZ | sp | 40 | 6 | 9 | 7 | 6 | 1 | 0 | 11 | 7 | 0 | 9.2 | 2.8 | 12.3 | 6.0 | 1.0 | 2.1 | 1.33 |
| Jimmy Gobble* |   | mr | 24 | 4 | 2 | 1 | 1 | 4 | 0 | 3 | 0 | 0 | 10.2 | 3.1 | 13.4 | 8.6 | 1.3 | 2.8 | 1.48 |
| Edgar Gonzalez |   | mr | 23 | 3 | 1 | 0 | 3 | 2 | 0 | 4 | 1 | 0 | 9.5 | 1.9 | 12.0 | 5.9 | 1.5 | 3.1 | 1.27 |
| Enrique Gonzalez | CCL | sp | 23 | 2 | 6 | 0 | 4 | 1 | 0 | 7 | 3 | 0 | 9.6 | 2.9 | 12.9 | 5.6 | 1.2 | 1.9 | 1.39 |
| Geremi Gonzalez |   | mr | 31 | 3 | 2 | 2 | 2 | 0 | 0 | 6 | 3 | 0 | 11.4 | 3.7 | 15.4 | 7.1 | 1.6 | 1.9 | 1.68 |
| Mike Gonzalez* | BT | cl | 28 | 3 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 0 | 7.0 | 5.2 | 12.5 | 10.7 | 0.2 | 2.1 | 1.35 |
| Tom Gordon | BT | cl | 38 | 6 | 0 | 4 | 1 | 3 | 0 | 2 | 1 | 0 | 8.0 | 3.3 | 11.5 | 10.3 | 1.4 | 3.1 | 1.26 |
| Tom Gorzelanny* | LON | sp | 23 | 4 | 2 | 2 | 4 | 3 | 0 | 7 | 4 | 0 | 7.3 | 4.5 | 12.4 | 5.8 | 0.4 | 1.3 | 1.31 |
| Mike Gosling* |   | mr | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.8 | 6.8 | 20.3 | 6.8 | 6.8 | 1.0 | 1.50 |
| John Grabow* |   | mr | 27 | 2 | 1 | 3 | 3 | 0 | 0 | 5 | 3 | 0 | 8.8 | 3.9 | 13.0 | 8.5 | 0.9 | 2.2 | 1.41 |
| Danny Graves |   | mr | 32 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 11.6 | 3.2 | 14.8 | 1.9 | 1.9 | 0.6 | 1.64 |
| Sean Green |   | mr | 27 | 1 | 0 | 1 | 2 | 2 | 0 | 1 | 1 | 0 | 9.6 | 3.7 | 13.8 | 4.2 | 0.6 | 1.2 | 1.47 |
| Kevin Gregg |   | mr | 28 | 5 | 0 | 0 | 2 | 6 | 0 | 0 | 3 | 1 | 10.1 | 2.4 | 12.8 | 8.2 | 1.1 | 3.4 | 1.39 |
| Zack Greinke | COP | mr | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 9.9 | 4.3 | 14.2 | 7.1 | 1.4 | 1.7 | 1.58 |
| Jason Grilli |   | mr | 29 | 2 | 1 | 3 | 5 | 5 | 0 | 2 | 4 | 0 | 8.9 | 3.6 | 13.2 | 4.5 | 0.9 | 1.2 | 1.39 |
| Jason Grimsley |   | mr | 38 | 0 | 0 | 2 | 0 | 1 | 0 | 3 | 0 | 0 | 9.8 | 2.6 | 12.4 | 3.3 | 1.3 | 1.3 | 1.37 |
| Kevin Gryboski |   | mr | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 22.2 | 3.2 | 27.0 | 6.4 | 4.8 | 2.0 | 2.82 |
| Eddie Guardado* |   | cl | 35 | 0 | 1 | 2 | 1 | 0 | 0 | 3 | 1 | 0 | 10.7 | 3.2 | 14.1 | 9.5 | 2.4 | 3.0 | 1.54 |
| Matt Guerrier |   | mr | 27 | 1 | 3 | 0 | 0 | 6 | 0 | 3 | 4 | 0 | 10.1 | 2.7 | 12.8 | 4.8 | 1.2 | 1.8 | 1.42 |
| Jeremy Guthrie |   | mr | 27 | 2 | 1 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 11.2 | 7.0 | 19.1 | 6.5 | 0.9 | 0.9 | 2.02 |
| Angel Guzman |   | sp | 24 | 5 | 3 | 1 | 6 | 8 | 1 | 5 | 3 | 0 | 10.9 | 5.9 | 17.8 | 9.6 | 1.4 | 1.6 | 1.88 |
| Charlie Haeger |   | mr | 22 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.9 | 6.4 | 12.3 | 9.3 | 0.0 | 1.5 | 1.36 |
| John Halama* |   | mr | 34 | 1 | 2 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 11.7 | 4.0 | 15.6 | 3.7 | 1.8 | 0.9 | 1.74 |
| Roy Halladay | ROK | sp | 29 | 20 | 5 | 5 | 5 | 3 | 0 | 3 | 5 | 0 | 8.5 | 1.4 | 10.1 | 5.4 | 0.8 | 3.9 | 1.10 |
| Brad Halsey* |   | mr | 25 | 10 | 3 | 7 | 5 | 7 | 0 | 3 | 2 | 0 | 10.3 | 4.4 | 15.2 | 5.1 | 1.0 | 1.2 | 1.63 |
| Cole Hamels* | WIZ | sp | 22 | 9 | 2 | 4 | 3 | 5 | 0 | 6 | 8 | 0 | 8.0 | 3.3 | 11.4 | 9.9 | 1.3 | 3.0 | 1.25 |
| Jason Hammel |   | sp | 23 | 1 | 2 | 0 | 1 | 3 | 2 | 0 | 3 | 0 | 12.5 | 4.3 | 17.0 | 6.5 | 1.4 | 1.5 | 1.86 |
| Chris Hammond* |   | mr | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 11.3 | 1.6 | 12.9 | 7.2 | 1.6 | 4.6 | 1.43 |
| Justin Hampson* |   | mr | 26 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 14.3 | 3.8 | 18.8 | 6.8 | 2.3 | 1.8 | 2.00 |
| Tim Hamulack* |   | mr | 29 | 0 | 0 | 1 | 2 | 2 | 1 | 1 | 0 | 0 | 9.5 | 5.8 | 15.9 | 9.0 | 1.9 | 1.5 | 1.71 |
| Josh Hancock | MUL | mr | 28 | 4 | 0 | 2 | 1 | 3 | 1 | 4 | 4 | 0 | 8.2 | 2.7 | 11.0 | 5.8 | 1.1 | 2.2 | 1.21 |
| Devern Hansack |   | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 0.9 | 6.3 | 7.2 | 1.8 | 8.0 | 0.70 |
| Craig Hansen |   | mr | 22 | 4 | 0 | 0 | 4 | 1 | 0 | 3 | 3 | 0 | 10.9 | 3.6 | 15.4 | 7.1 | 1.2 | 2.0 | 1.61 |
| Aaron Harang | GEO | sp | 28 | 16 | 8 | 8 | 8 | 6 | 1 | 21 | 8 | 0 | 9.3 | 2.2 | 11.8 | 8.3 | 1.1 | 3.9 | 1.27 |
| Rich Harden | COP | sp | 24 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 6.0 | 5.0 | 11.2 | 9.4 | 1.0 | 1.9 | 1.22 |
| Dan Haren | LON | sp | 25 | 10 | 4 | 6 | 10 | 10 | 0 | 3 | 3 | 0 | 9.0 | 1.8 | 11.3 | 7.1 | 1.3 | 3.9 | 1.21 |
| Travis Harper |   | mr | 30 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 | 0 | 13.3 | 2.8 | 16.5 | 6.9 | 1.3 | 2.5 | 1.79 |
| Jeff Harris |   | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.1 | 0.0 | 8.1 | 2.7 | 0.0 | 99.0 | 0.90 |
| Chad Harville |   | mr | 29 | 7 | 1 | 2 | 0 | 4 | 2 | 2 | 1 | 0 | 9.7 | 4.8 | 14.5 | 6.6 | 1.1 | 1.4 | 1.61 |
| LaTroy Hawkins |   | mr | 33 | 7 | 2 | 3 | 0 | 2 | 0 | 1 | 2 | 0 | 10.9 | 2.2 | 13.1 | 4.0 | 0.6 | 1.8 | 1.46 |
| Aaron Heilman | WIZ | mr | 27 | 9 | 0 | 2 | 3 | 5 | 0 | 7 | 2 | 0 | 7.6 | 2.9 | 10.8 | 7.6 | 0.5 | 2.6 | 1.16 |
| Rick Helling |   | mr | 35 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | 0 | 6.4 | 3.9 | 10.3 | 8.2 | 1.5 | 2.1 | 1.14 |
| Ben Hendrickson |   | sp | 25 | 5 | 0 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 15.8 | 6.8 | 22.5 | 6.0 | 0.0 | 0.9 | 2.50 |
| Mark Hendrickson* | MUL | sp | 32 | 9 | 3 | 0 | 4 | 6 | 1 | 5 | 4 | 0 | 9.5 | 3.4 | 13.1 | 5.4 | 0.9 | 1.6 | 1.43 |
| Sean Henn* |   | mr | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 10.6 | 4.8 | 16.4 | 6.8 | 1.9 | 1.4 | 1.71 |
| Brad Hennessey |   | mr | 26 | 11 | 3 | 1 | 10 | 3 | 0 | 6 | 2 | 1 | 8.3 | 3.8 | 13.0 | 3.8 | 1.1 | 1.0 | 1.35 |
| Clay Hensley | WIZ | sp | 26 | 12 | 4 | 7 | 3 | 3 | 0 | 10 | 3 | 0 | 8.4 | 3.7 | 12.2 | 5.9 | 0.7 | 1.6 | 1.34 |
| Matt Herges |   | mr | 36 | 0 | 2 | 5 | 3 | 1 | 0 | 3 | 1 | 0 | 11.9 | 3.5 | 15.8 | 4.6 | 0.6 | 1.3 | 1.72 |
| Dustin Hermanson |   | mr | 33 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 8.1 | 1.3 | 10.8 | 6.8 | 2.7 | 5.0 | 1.05 |
| Felix Hernandez | ROK | sp | 20 | 14 | 5 | 2 | 6 | 11 | 0 | 2 | 3 | 0 | 9.2 | 2.8 | 12.3 | 8.3 | 1.1 | 2.9 | 1.34 |
| Livan Hernandez |   | sp | 31 | 14 | 4 | 6 | 4 | 1 | 0 | 16 | 8 | 0 | 10.3 | 3.3 | 13.7 | 5.3 | 1.2 | 1.6 | 1.50 |
| Orlando Hernandez | Pal | sp | 36 | 20 | 7 | 5 | 12 | 1 | 3 | 7 | 5 | 0 | 8.6 | 3.4 | 12.6 | 9.1 | 1.2 | 2.7 | 1.33 |
| Roberto Hernandez |   | mr | 41 | 6 | 2 | 8 | 1 | 5 | 0 | 5 | 1 | 0 | 8.6 | 4.5 | 13.3 | 6.8 | 0.7 | 1.5 | 1.46 |
| Runelvys Hernandez |   | sp | 28 | 2 | 2 | 0 | 6 | 3 | 2 | 3 | 8 | 0 | 11.9 | 3.9 | 16.3 | 4.1 | 1.8 | 1.0 | 1.76 |
| Rich Hill* | BT | sp | 26 | 10 | 3 | 1 | 2 | 3 | 0 | 8 | 3 | 0 | 7.5 | 3.5 | 11.2 | 8.2 | 1.4 | 2.3 | 1.23 |
| Shawn Hill |   | sp | 25 | 2 | 1 | 2 | 3 | 1 | 0 | 2 | 1 | 0 | 10.6 | 2.9 | 14.2 | 3.9 | 0.5 | 1.3 | 1.50 |
| Jason Hirsh |   | sp | 24 | 2 | 1 | 2 | 3 | 4 | 0 | 0 | 1 | 0 | 9.7 | 4.4 | 14.7 | 5.8 | 2.2 | 1.3 | 1.57 |
| James Hoey |   | mr | 23 | 1 | 0 | 0 | 2 | 0 | 1 | 1 | 2 | 0 | 13.0 | 4.7 | 19.6 | 5.6 | 0.9 | 1.2 | 1.97 |
| Trevor Hoffman | Pal | cl | 38 | 2 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 6.9 | 1.9 | 8.9 | 7.1 | 0.9 | 3.8 | 0.97 |
| Mike Holtz* |   | mr | 33 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 16.2 | 21.6 | 43.2 | 10.8 | 0.0 | 0.5 | 4.20 |
| J.P. Howell* | MID | sp | 23 | 3 | 1 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 11.1 | 3.0 | 14.7 | 7.0 | 0.9 | 2.4 | 1.56 |
| Bob Howry | COP | mr | 32 | 4 | 5 | 4 | 3 | 1 | 0 | 5 | 3 | 0 | 8.2 | 2.0 | 10.6 | 8.3 | 0.9 | 4.2 | 1.13 |
| Jon Huber |   | mr | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 5.4 | 3.2 | 8.6 | 5.9 | 0.0 | 1.8 | 0.96 |
| Luke Hudson | MID | sp | 29 | 1 | 2 | 1 | 4 | 6 | 0 | 0 | 3 | 0 | 9.6 | 3.4 | 13.3 | 5.6 | 0.6 | 1.7 | 1.44 |
| Tim Hudson | GEO | sp | 30 | 23 | 4 | 10 | 9 | 7 | 0 | 8 | 3 | 0 | 9.7 | 3.3 | 13.3 | 5.8 | 1.0 | 1.8 | 1.44 |
| Travis Hughes |   | mr | 28 | 0 | 0 | 1 | 3 | 1 | 0 | 2 | 1 | 0 | 10.3 | 4.8 | 17.5 | 3.2 | 1.6 | 0.7 | 1.68 |
| Philip Humber |   | mr | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 4.5 | 4.5 | 9.0 | 0.0 | 2.0 | 0.50 |
| Jason Isringhausen | Pal | cl | 33 | 5 | 1 | 3 | 3 | 3 | 0 | 1 | 3 | 0 | 7.3 | 5.9 | 13.6 | 8.0 | 1.5 | 1.4 | 1.46 |
| Edwin Jackson |   | mr | 22 | 3 | 0 | 0 | 1 | 3 | 1 | 2 | 2 | 0 | 10.4 | 6.2 | 16.8 | 6.7 | 0.5 | 1.1 | 1.84 |
| Zach Jackson* |   | sp | 23 | 4 | 0 | 0 | 4 | 1 | 0 | 1 | 1 | 0 | 11.3 | 3.3 | 15.5 | 5.2 | 1.4 | 1.6 | 1.62 |
| Chuck James* | Pal | sp | 24 | 14 | 3 | 2 | 6 | 2 | 0 | 8 | 7 | 1 | 7.6 | 3.6 | 11.6 | 6.9 | 1.5 | 1.9 | 1.24 |
| Casey Janssen | OTR | sp | 24 | 2 | 3 | 3 | 7 | 3 | 2 | 2 | 2 | 0 | 9.9 | 2.0 | 12.5 | 4.2 | 1.1 | 2.1 | 1.32 |
| Kevin Jarvis |   | mr | 36 | 2 | 0 | 1 | 2 | 2 | 0 | 1 | 3 | 0 | 12.9 | 3.5 | 17.0 | 4.2 | 1.0 | 1.2 | 1.82 |
| Bobby Jenks | OTR | cl | 25 | 11 | 2 | 10 | 2 | 3 | 0 | 4 | 2 | 0 | 8.5 | 4.0 | 12.8 | 10.3 | 0.6 | 2.6 | 1.39 |
| Jason Jennings | CCL | sp | 27 | 16 | 7 | 7 | 3 | 10 | 0 | 8 | 6 | 0 | 8.7 | 3.6 | 12.5 | 6.0 | 0.7 | 1.7 | 1.37 |
| Cesar Jimenez* |   | mr | 21 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 16.0 | 4.9 | 20.9 | 3.7 | 4.9 | 0.8 | 2.32 |
| Ubaldo Jimenez |   | sp | 22 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.9 | 3.5 | 9.4 | 3.5 | 1.2 | 1.0 | 1.04 |
| Jason Johnson |   | sp | 32 | 19 | 0 | 0 | 5 | 8 | 0 | 1 | 8 | 1 | 12.5 | 2.7 | 15.7 | 4.2 | 1.1 | 1.5 | 1.70 |
| Jim Johnson |   | sp | 23 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 27.0 | 9.0 | 39.0 | 0.0 | 3.0 | 0.0 | 4.00 |
| Josh Johnson | LON | sp | 22 | 9 | 8 | 6 | 4 | 3 | 1 | 11 | 0 | 0 | 7.8 | 3.9 | 11.9 | 7.6 | 0.8 | 2.0 | 1.30 |
| Randy Johnson* | ROK | sp | 42 | 21 | 10 | 1 | 10 | 3 | 2 | 6 | 7 | 0 | 8.5 | 2.6 | 11.6 | 7.6 | 1.2 | 2.9 | 1.24 |
| Tyler Johnson* |   | mr | 25 | 3 | 0 | 2 | 4 | 2 | 0 | 1 | 1 | 0 | 8.2 | 5.7 | 14.9 | 9.2 | 1.2 | 1.6 | 1.54 |
| Greg Jones |   | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 12.0 | 3.0 | 15.0 | 1.5 | 1.5 | 0.5 | 1.67 |
| Todd Jones | MUL | cl | 38 | 0 | 0 | 3 | 3 | 2 | 0 | 3 | 1 | 0 | 9.8 | 1.5 | 11.8 | 3.9 | 0.6 | 2.5 | 1.27 |
| Jorge Julio |   | cl | 27 | 5 | 2 | 2 | 1 | 9 | 0 | 1 | 0 | 0 | 7.1 | 4.8 | 12.0 | 12.0 | 1.4 | 2.5 | 1.32 |
| Steve Karsay |   | mr | 34 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 12.5 | 2.9 | 16.4 | 4.8 | 3.9 | 1.7 | 1.71 |
| Jeff Karstens | BON | sp | 23 | 2 | 0 | 2 | 1 | 3 | 1 | 0 | 2 | 0 | 8.4 | 2.3 | 11.0 | 3.4 | 1.3 | 1.5 | 1.20 |
| Scott Kazmir* | GEO | sp | 22 | 15 | 3 | 3 | 2 | 6 | 0 | 0 | 5 | 0 | 8.2 | 3.2 | 11.6 | 10.1 | 0.9 | 3.1 | 1.27 |
| Randy Keisler* |   | mr | 30 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.6 | 1.8 | 14.4 | 4.5 | 2.7 | 2.5 | 1.60 |
| Joe Kennedy* |   | mr | 27 | 0 | 0 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | 8.7 | 3.3 | 12.3 | 7.5 | 0.3 | 2.2 | 1.34 |
| Logan Kensing |   | mr | 23 | 3 | 1 | 2 | 3 | 0 | 0 | 3 | 0 | 0 | 7.2 | 4.5 | 12.4 | 10.8 | 1.4 | 2.4 | 1.30 |
| Bobby Keppel |   | sp | 24 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 2 | 0 | 11.8 | 3.9 | 16.0 | 5.2 | 1.6 | 1.3 | 1.75 |
| Byung-Hyun Kim |   | sp | 27 | 24 | 7 | 8 | 8 | 5 | 1 | 8 | 5 | 0 | 10.4 | 3.5 | 14.4 | 7.5 | 1.0 | 2.1 | 1.55 |
| Sun-Woo Kim |   | mr | 28 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 3 | 0 | 15.8 | 5.3 | 21.7 | 5.3 | 3.3 | 1.0 | 2.34 |
| Ray King* |   | mr | 32 | 2 | 1 | 0 | 2 | 3 | 0 | 3 | 3 | 0 | 11.3 | 4.0 | 15.7 | 4.6 | 1.2 | 1.1 | 1.70 |
| Josh Kinney |   | mr | 27 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.1 | 2.9 | 9.4 | 7.9 | 1.1 | 2.8 | 1.00 |
| Steve Kline* |   | mr | 33 | 0 | 1 | 3 | 1 | 1 | 0 | 6 | 1 | 0 | 9.2 | 4.5 | 13.9 | 5.7 | 0.5 | 1.3 | 1.53 |
| Dan Kolb |   | mr | 31 | 2 | 0 | 1 | 1 | 5 | 0 | 1 | 3 | 0 | 9.9 | 3.7 | 13.8 | 4.8 | 0.7 | 1.3 | 1.51 |
| Shane Komine |   | sp | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10.0 | 8.0 | 18.0 | 1.0 | 3.0 | 0.1 | 2.00 |
| Mike Koplove |   | mr | 29 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 15.0 | 6.0 | 21.0 | 3.0 | 0.0 | 0.5 | 2.33 |
| John Koronka* |   | sp | 25 | 9 | 3 | 2 | 5 | 4 | 1 | 1 | 7 | 0 | 10.4 | 3.4 | 14.2 | 4.4 | 1.2 | 1.3 | 1.54 |
| Hong-Chih Kuo* | Pal | mr | 24 | 5 | 4 | 5 | 1 | 2 | 0 | 2 | 1 | 0 | 8.1 | 5.0 | 13.3 | 10.7 | 0.5 | 2.2 | 1.46 |
| John Lackey | COP | sp | 27 | 12 | 4 | 4 | 9 | 16 | 0 | 8 | 6 | 2 | 8.4 | 3.0 | 11.7 | 7.9 | 0.6 | 2.6 | 1.26 |
| Juan Lara* |   | mr | 25 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.2 | 1.8 | 9.0 | 3.6 | 0.0 | 2.0 | 1.00 |
| Brandon League | CRH | mr | 23 | 1 | 1 | 2 | 3 | 0 | 0 | 2 | 0 | 0 | 7.2 | 1.9 | 9.7 | 6.1 | 0.6 | 3.2 | 1.01 |
| Wilfredo Ledezma* |   | mr | 25 | 2 | 1 | 0 | 2 | 2 | 0 | 2 | 1 | 0 | 9.0 | 3.4 | 12.7 | 5.8 | 0.7 | 1.7 | 1.38 |
| Cliff Lee* | MID | sp | 27 | 7 | 3 | 3 | 8 | 3 | 0 | 3 | 6 | 0 | 10.0 | 2.6 | 13.0 | 5.8 | 1.3 | 2.2 | 1.41 |
| Justin Lehr |   | mr | 28 | 4 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 13.8 | 4.0 | 18.4 | 6.9 | 1.1 | 1.7 | 1.98 |
| Anthony Lerew |   | mr | 23 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 22.5 | 13.5 | 40.5 | 4.5 | 0.0 | 0.3 | 4.00 |
| Jon Lester* | EDG | sp | 22 | 9 | 6 | 1 | 5 | 5 | 0 | 2 | 8 | 0 | 10.1 | 4.8 | 15.4 | 6.6 | 0.8 | 1.4 | 1.65 |
| Colby Lewis |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24.0 | 3.0 | 27.0 | 15.0 | 3.0 | 5.0 | 3.00 |
| Brad Lidge | Pal | cl | 29 | 7 | 0 | 4 | 6 | 11 | 0 | 6 | 2 | 0 | 8.3 | 4.3 | 13.3 | 12.5 | 1.2 | 2.9 | 1.40 |
| Cory Lidle |   | sp | 34 | 8 | 8 | 4 | 11 | 5 | 0 | 5 | 4 | 0 | 9.5 | 3.1 | 13.2 | 6.9 | 1.6 | 2.2 | 1.40 |
| Jon Lieber |   | sp | 36 | 8 | 3 | 3 | 6 | 3 | 0 | 6 | 4 | 0 | 10.5 | 1.3 | 12.1 | 5.4 | 1.4 | 4.2 | 1.31 |
| Ted Lilly* | OTR | sp | 30 | 14 | 3 | 6 | 4 | 7 | 4 | 4 | 2 | 0 | 8.9 | 4.0 | 13.1 | 7.9 | 1.4 | 2.0 | 1.43 |
| Jose Lima |   | sp | 33 | 1 | 0 | 0 | 2 | 1 | 1 | 2 | 1 | 0 | 13.0 | 5.2 | 19.2 | 6.2 | 1.6 | 1.2 | 2.02 |
| Scott Linebrink |   | mr | 29 | 8 | 1 | 3 | 1 | 2 | 0 | 1 | 2 | 0 | 8.3 | 2.6 | 11.1 | 8.1 | 1.1 | 3.1 | 1.22 |
| Francisco Liriano* | ROK | sp | 22 | 9 | 0 | 0 | 1 | 9 | 1 | 4 | 2 | 0 | 6.6 | 2.4 | 9.1 | 10.7 | 0.7 | 4.5 | 1.00 |
| Wes Littleton |   | mr | 23 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.7 | 3.2 | 9.4 | 4.2 | 0.5 | 1.3 | 0.99 |
| Bobby Livingston* |   | mr | 23 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 16.2 | 10.8 | 30.6 | 5.4 | 3.6 | 0.5 | 3.00 |
| Esteban Loaiza |   | sp | 34 | 10 | 3 | 3 | 5 | 2 | 0 | 5 | 8 | 0 | 10.4 | 2.3 | 13.0 | 5.6 | 1.0 | 2.4 | 1.42 |
| Kameron Loe |   | sp | 24 | 5 | 0 | 0 | 1 | 3 | 0 | 1 | 3 | 0 | 12.1 | 2.5 | 14.7 | 3.9 | 1.1 | 1.5 | 1.62 |
| Adam Loewen* | MID | sp | 22 | 11 | 7 | 0 | 8 | 3 | 1 | 1 | 4 | 0 | 8.9 | 5.0 | 14.5 | 7.9 | 0.6 | 1.6 | 1.54 |
| Boone Logan* |   | mr | 21 | 0 | 0 | 2 | 3 | 1 | 0 | 1 | 1 | 0 | 10.9 | 7.8 | 20.3 | 7.8 | 1.0 | 1.0 | 2.08 |
| Kyle Lohse | MID | sp | 27 | 2 | 3 | 4 | 6 | 3 | 1 | 8 | 5 | 0 | 10.7 | 3.1 | 14.2 | 6.9 | 1.1 | 2.2 | 1.53 |
| Braden Looper | MAD | mr | 31 | 3 | 1 | 5 | 2 | 0 | 0 | 7 | 5 | 0 | 9.3 | 2.5 | 12.0 | 5.0 | 0.4 | 2.0 | 1.31 |
| Javier Lopez* |   | mr | 28 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 7.0 | 5.4 | 13.5 | 5.9 | 0.5 | 1.1 | 1.38 |
| Rodrigo Lopez |   | sp | 30 | 9 | 10 | 2 | 4 | 6 | 1 | 5 | 5 | 0 | 11.1 | 2.8 | 14.1 | 6.5 | 1.5 | 2.3 | 1.55 |
| Derek Lowe | BON | sp | 33 | 26 | 4 | 2 | 5 | 3 | 2 | 7 | 2 | 0 | 9.1 | 2.3 | 11.6 | 5.1 | 0.6 | 2.2 | 1.27 |
| Mark Lowe |   | mr | 23 | 0 | 0 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 5.8 | 4.3 | 11.1 | 9.6 | 0.5 | 2.2 | 1.13 |
| Noah Lowry* |   | sp | 25 | 6 | 4 | 2 | 6 | 2 | 1 | 11 | 7 | 0 | 9.4 | 3.2 | 12.9 | 4.7 | 1.2 | 1.5 | 1.39 |
| Ruddy Lugo | GEO | mr | 26 | 2 | 3 | 0 | 5 | 3 | 0 | 1 | 7 | 0 | 7.9 | 3.9 | 12.4 | 5.1 | 0.4 | 1.3 | 1.32 |
| Brandon Lyon | Pal | mr | 26 | 2 | 0 | 7 | 0 | 1 | 0 | 3 | 4 | 0 | 8.8 | 2.9 | 11.7 | 6.0 | 0.9 | 2.1 | 1.30 |
| Chris Mabeus |   | mr | 27 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 21.6 | 16.2 | 37.8 | 10.8 | 5.4 | 0.7 | 4.20 |
| Mike MacDougal |   | mr | 29 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 6.5 | 1.9 | 8.7 | 6.5 | 0.3 | 3.5 | 0.93 |
| Greg Maddux | Pal | sp | 40 | 25 | 6 | 7 | 0 | 0 | 0 | 11 | 5 | 0 | 9.4 | 1.6 | 11.0 | 5.0 | 0.9 | 3.2 | 1.22 |
| Ryan Madson | CCL | mr | 25 | 14 | 6 | 4 | 10 | 12 | 0 | 9 | 3 | 0 | 11.8 | 3.3 | 15.8 | 6.6 | 1.3 | 2.0 | 1.68 |
| Ron Mahay* |   | mr | 35 | 2 | 2 | 2 | 0 | 1 | 0 | 1 | 1 | 0 | 8.5 | 4.4 | 12.9 | 8.8 | 1.1 | 2.0 | 1.44 |
| Paul Maholm* |   | sp | 24 | 13 | 11 | 6 | 12 | 3 | 1 | 7 | 4 | 0 | 10.3 | 4.1 | 15.1 | 6.0 | 1.0 | 1.4 | 1.61 |
| John Maine | BT | sp | 25 | 6 | 3 | 1 | 2 | 3 | 0 | 3 | 1 | 0 | 6.9 | 3.3 | 10.4 | 7.1 | 1.5 | 2.2 | 1.13 |
| Gary Majewski |   | mr | 26 | 2 | 3 | 3 | 4 | 6 | 0 | 1 | 3 | 0 | 10.1 | 3.7 | 14.3 | 5.5 | 0.6 | 1.5 | 1.54 |
| Julio Manon |   | mr | 32 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 10.3 | 7.2 | 18.4 | 9.9 | 2.3 | 1.4 | 1.95 |
| Shaun Marcum | COP | sp | 24 | 2 | 1 | 3 | 4 | 1 | 0 | 1 | 2 | 0 | 10.0 | 4.4 | 14.8 | 7.5 | 1.6 | 1.7 | 1.60 |
| Carlos Marmol | WIZ | sp | 23 | 11 | 5 | 2 | 5 | 3 | 1 | 6 | 2 | 0 | 8.3 | 6.9 | 15.8 | 6.9 | 1.6 | 1.0 | 1.69 |
| Mike Maroth* |   | sp | 28 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 10.7 | 2.7 | 13.6 | 4.0 | 1.8 | 1.5 | 1.49 |
| Jason Marquis |   | sp | 27 | 10 | 5 | 2 | 16 | 2 | 1 | 12 | 3 | 0 | 10.2 | 3.5 | 14.4 | 4.4 | 1.6 | 1.3 | 1.52 |
| Sean Marshall* | LON | sp | 23 | 12 | 5 | 3 | 7 | 6 | 0 | 7 | 1 | 0 | 9.5 | 4.2 | 14.2 | 5.5 | 1.4 | 1.3 | 1.52 |
| Damaso Marte* | WIZ | mr | 31 | 4 | 2 | 6 | 4 | 3 | 1 | 8 | 3 | 0 | 7.9 | 4.8 | 13.3 | 9.7 | 0.8 | 2.0 | 1.41 |
| Tom Martin* |   | mr | 36 | 2 | 2 | 5 | 4 | 1 | 0 | 1 | 1 | 0 | 9.2 | 3.7 | 13.6 | 6.9 | 0.6 | 1.8 | 1.44 |
| Carlos Martinez |   | mr | 24 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 7.8 | 5.2 | 13.1 | 9.6 | 0.0 | 1.8 | 1.45 |
| Pedro Martinez | WIZ | sp | 34 | 13 | 1 | 2 | 10 | 2 | 1 | 6 | 5 | 0 | 7.3 | 2.6 | 10.7 | 9.3 | 1.3 | 3.5 | 1.11 |
| Nick Masset |   | mr | 24 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 9.3 | 2.1 | 13.5 | 4.2 | 0.0 | 2.0 | 1.27 |
| Tom Mastny |   | cl | 25 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 0 | 9.4 | 4.4 | 14.3 | 7.7 | 0.6 | 1.8 | 1.53 |
| Juan Mateo |   | sp | 23 | 1 | 1 | 1 | 3 | 1 | 0 | 5 | 2 | 0 | 10.1 | 4.5 | 15.2 | 6.9 | 1.2 | 1.5 | 1.62 |
| Julio Mateo |   | mr | 28 | 4 | 1 | 8 | 3 | 1 | 0 | 2 | 5 | 0 | 10.4 | 3.7 | 14.6 | 5.2 | 1.0 | 1.4 | 1.57 |
| Scott Mathieson |   | sp | 22 | 1 | 0 | 1 | 1 | 2 | 1 | 5 | 1 | 0 | 11.6 | 3.9 | 15.7 | 6.8 | 1.9 | 1.8 | 1.71 |
| Joe Mays |   | sp | 30 | 1 | 0 | 2 | 0 | 6 | 0 | 2 | 2 | 0 | 13.9 | 4.6 | 18.5 | 4.4 | 2.0 | 1.0 | 2.05 |
| Macay McBride* |   | mr | 23 | 0 | 0 | 4 | 1 | 3 | 0 | 2 | 0 | 0 | 8.4 | 5.1 | 13.7 | 7.3 | 0.3 | 1.4 | 1.50 |
| Brandon McCarthy |   | mr | 22 | 8 | 3 | 9 | 0 | 5 | 0 | 3 | 1 | 0 | 8.2 | 3.5 | 11.7 | 7.3 | 1.8 | 2.1 | 1.30 |
| Seth McClung |   | mr | 25 | 15 | 5 | 5 | 3 | 7 | 0 | 1 | 9 | 0 | 10.5 | 5.9 | 16.7 | 5.2 | 1.2 | 0.9 | 1.83 |
| Dustin McGowan |   | mr | 24 | 3 | 1 | 2 | 2 | 3 | 1 | 0 | 1 | 0 | 11.5 | 8.2 | 20.4 | 7.2 | 0.7 | 0.9 | 2.20 |
| Marty McLeary |   | mr | 31 | 4 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 8.7 | 3.1 | 11.7 | 4.1 | 0.5 | 1.3 | 1.30 |
| Brian Meadows |   | mr | 30 | 5 | 1 | 4 | 0 | 2 | 0 | 1 | 6 | 1 | 11.6 | 1.9 | 13.6 | 4.5 | 1.8 | 2.3 | 1.51 |
| Gil Meche | CRH | sp | 27 | 5 | 7 | 2 | 8 | 4 | 2 | 3 | 2 | 0 | 8.8 | 4.0 | 13.3 | 7.5 | 1.2 | 1.9 | 1.43 |
| Brandon Medders |   | mr | 26 | 4 | 1 | 3 | 2 | 2 | 0 | 3 | 2 | 0 | 9.5 | 3.5 | 13.3 | 5.9 | 0.6 | 1.7 | 1.45 |
| Kent Mercker* |   | mr | 38 | 1 | 0 | 1 | 0 | 1 | 1 | 3 | 1 | 0 | 8.9 | 3.5 | 12.4 | 5.4 | 1.9 | 1.5 | 1.38 |
| Cla Meredith | WIZ | mr | 23 | 4 | 1 | 3 | 2 | 0 | 2 | 1 | 0 | 0 | 5.3 | 1.1 | 6.8 | 6.6 | 0.5 | 6.2 | 0.71 |
| Jose Mesa |   | mr | 40 | 0 | 3 | 6 | 5 | 4 | 1 | 2 | 2 | 0 | 9.1 | 4.5 | 14.2 | 4.9 | 1.1 | 1.1 | 1.51 |
| Randy Messenger |   | mr | 24 | 6 | 1 | 2 | 1 | 3 | 0 | 5 | 2 | 0 | 10.7 | 3.6 | 14.5 | 6.7 | 1.2 | 1.9 | 1.59 |
| Dan Miceli |   | mr | 35 | 2 | 1 | 3 | 1 | 3 | 0 | 3 | 3 | 0 | 7.0 | 5.6 | 12.9 | 5.1 | 1.1 | 0.9 | 1.41 |
| Chris Michalak* |   | sp | 35 | 2 | 2 | 2 | 3 | 1 | 1 | 5 | 0 | 0 | 10.8 | 4.1 | 15.7 | 2.6 | 1.5 | 0.6 | 1.66 |
| Andrew Miller* |   | mr | 21 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 7.0 | 8.7 | 17.4 | 5.2 | 0.0 | 0.6 | 1.74 |
| Matt Miller |   | mr | 34 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 6.3 | 5.2 | 12.6 | 6.9 | 1.1 | 1.3 | 1.28 |
| Trever Miller* | CCL | mr | 33 | 2 | 1 | 2 | 4 | 1 | 0 | 1 | 2 | 0 | 7.5 | 2.3 | 10.5 | 9.9 | 1.2 | 4.3 | 1.09 |
| Wade Miller |   | sp | 29 | 2 | 0 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 7.9 | 7.5 | 15.8 | 8.3 | 1.7 | 1.1 | 1.71 |
| Kevin Millwood | CCL | sp | 31 | 10 | 3 | 4 | 4 | 6 | 0 | 8 | 3 | 0 | 9.5 | 2.2 | 11.9 | 6.6 | 1.0 | 3.0 | 1.31 |
| Eric Milton* |   | sp | 30 | 3 | 2 | 4 | 5 | 2 | 0 | 6 | 3 | 0 | 9.6 | 2.5 | 12.4 | 5.3 | 1.7 | 2.1 | 1.34 |
| Zach Miner |   | sp | 24 | 8 | 5 | 1 | 0 | 1 | 0 | 2 | 2 | 0 | 9.7 | 3.1 | 12.8 | 5.7 | 1.1 | 1.8 | 1.42 |
| Patrick Misch* |   | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 0.0 | 18.0 | 9.0 | 0.0 | 99.0 | 2.00 |
| Sergio Mitre |   | sp | 25 | 5 | 2 | 3 | 6 | 1 | 0 | 2 | 1 | 0 | 9.7 | 4.4 | 15.4 | 6.8 | 1.5 | 1.5 | 1.56 |
| Brian Moehler |   | sp | 34 | 5 | 6 | 3 | 5 | 2 | 1 | 7 | 2 | 0 | 12.1 | 2.8 | 15.3 | 4.3 | 1.4 | 1.5 | 1.66 |
| Agustin Montero |   | mr | 28 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 9.6 | 1.3 | 10.9 | 4.5 | 1.9 | 3.5 | 1.21 |
| Juan Morillo |   | sp | 22 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 18.0 | 6.8 | 27.0 | 9.0 | 6.8 | 1.3 | 2.75 |
| Matt Morris | CCL | sp | 31 | 13 | 3 | 9 | 14 | 1 | 3 | 9 | 5 | 0 | 9.4 | 2.7 | 12.8 | 5.1 | 1.0 | 1.9 | 1.35 |
| Dustin Moseley |   | sp | 24 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 18.0 | 1.6 | 19.6 | 2.5 | 2.5 | 1.5 | 2.18 |
| Guillermo Mota |   | mr | 32 | 9 | 1 | 4 | 0 | 2 | 0 | 0 | 3 | 0 | 8.9 | 3.9 | 12.8 | 7.4 | 1.8 | 1.9 | 1.42 |
| Jamie Moyer* |   | sp | 43 | 11 | 8 | 5 | 5 | 3 | 1 | 5 | 9 | 1 | 9.7 | 2.2 | 12.1 | 4.6 | 1.4 | 2.1 | 1.32 |
| Peter Moylan |   | mr | 27 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 10.8 | 3.0 | 13.8 | 8.4 | 0.6 | 2.8 | 1.53 |
| Edward Mujica |   | mr | 22 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 12.3 | 0.0 | 12.8 | 5.9 | 0.5 | 99.0 | 1.36 |
| Mark Mulder* |   | sp | 28 | 5 | 1 | 1 | 5 | 3 | 0 | 10 | 1 | 0 | 12.0 | 3.4 | 15.8 | 4.8 | 1.8 | 1.4 | 1.70 |
| Terry Mulholland* |   | mr | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 21.0 | 3.0 | 24.0 | 3.0 | 3.0 | 1.0 | 2.67 |
| Scott Munter |   | mr | 26 | 2 | 1 | 2 | 2 | 0 | 0 | 7 | 1 | 0 | 11.9 | 7.1 | 19.9 | 2.8 | 0.4 | 0.4 | 2.12 |
| Mike Mussina | GEO | sp | 37 | 15 | 4 | 1 | 5 | 3 | 0 | 1 | 1 | 0 | 8.4 | 1.6 | 10.2 | 7.8 | 1.0 | 4.9 | 1.11 |
| Brett Myers | Pal | sp | 25 | 13 | 5 | 3 | 3 | 3 | 0 | 7 | 4 | 0 | 8.8 | 2.9 | 11.8 | 8.6 | 1.3 | 3.0 | 1.30 |
| Mike Myers* |   | mr | 37 | 4 | 2 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 8.5 | 2.9 | 12.3 | 6.5 | 0.9 | 2.2 | 1.27 |
| Clint Nageotte |   | mr | 25 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 18.0 | 36.0 | 9.0 | 9.0 | 0.5 | 4.00 |
| Chris Narveson* |   | mr | 24 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 5.8 | 4.8 | 11.6 | 11.6 | 1.0 | 2.4 | 1.18 |
| Joe Nathan | WIZ | cl | 31 | 2 | 0 | 4 | 1 | 3 | 0 | 3 | 2 | 0 | 5.0 | 2.1 | 7.2 | 12.5 | 0.4 | 5.9 | 0.79 |
| Jeff Nelson |   | mr | 39 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10.1 | 16.9 | 27.0 | 6.8 | 3.4 | 0.4 | 3.00 |
| Joe Nelson |   | mr | 31 | 2 | 1 | 4 | 1 | 1 | 0 | 3 | 1 | 0 | 7.5 | 4.8 | 12.5 | 8.9 | 1.0 | 1.8 | 1.37 |
| Pat Neshek |   | mr | 25 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.6 | 1.5 | 7.1 | 12.9 | 1.5 | 8.8 | 0.78 |
| Fernando Nieve |   | mr | 23 | 4 | 1 | 5 | 2 | 1 | 0 | 5 | 3 | 0 | 8.1 | 3.8 | 12.1 | 6.5 | 1.7 | 1.7 | 1.33 |
| Dustin Nippert |   | sp | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 13.5 | 6.3 | 19.8 | 8.1 | 4.5 | 1.3 | 2.20 |
| Ricky Nolasco |   | sp | 23 | 6 | 6 | 5 | 10 | 7 | 0 | 8 | 6 | 0 | 10.1 | 2.6 | 13.4 | 6.4 | 1.3 | 2.4 | 1.41 |
| Roberto Novoa |   | mr | 26 | 10 | 0 | 5 | 6 | 4 | 0 | 2 | 2 | 0 | 9.1 | 3.8 | 13.6 | 6.3 | 1.8 | 1.7 | 1.43 |
| Leo Nunez |   | mr | 22 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 10.1 | 3.4 | 14.8 | 4.7 | 1.3 | 1.4 | 1.50 |
| Mike O'Connor* | BT | sp | 25 | 17 | 1 | 5 | 7 | 8 | 0 | 6 | 4 | 0 | 8.2 | 3.9 | 12.7 | 5.1 | 1.3 | 1.3 | 1.34 |
| Eric O'Flaherty* |   | mr | 21 | 0 | 0 | 3 | 0 | 2 | 0 | 1 | 0 | 0 | 14.7 | 4.9 | 19.6 | 4.9 | 1.6 | 1.0 | 2.18 |
| Ryan O'Malley* |   | sp | 26 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.1 | 5.0 | 12.8 | 2.8 | 0.0 | 0.6 | 1.34 |
| Tomo Ohka |   | sp | 30 | 4 | 2 | 1 | 5 | 4 | 0 | 8 | 4 | 0 | 9.1 | 3.2 | 12.8 | 4.6 | 1.1 | 1.4 | 1.37 |
| Will Ohman* | MAD | mr | 28 | 4 | 0 | 2 | 5 | 4 | 0 | 0 | 2 | 0 | 7.0 | 4.7 | 12.4 | 10.2 | 0.8 | 2.2 | 1.30 |
| Darren Oliver* |   | mr | 35 | 3 | 1 | 2 | 3 | 1 | 0 | 2 | 4 | 0 | 7.8 | 2.3 | 10.4 | 6.7 | 1.4 | 2.9 | 1.12 |
| Scott Olsen* | TON | sp | 22 | 8 | 8 | 1 | 7 | 8 | 0 | 7 | 2 | 0 | 8.0 | 3.7 | 12.1 | 8.3 | 1.1 | 2.2 | 1.30 |
| Ramon Ortiz |   | sp | 33 | 6 | 4 | 14 | 18 | 4 | 3 | 10 | 4 | 0 | 10.9 | 3.0 | 14.7 | 4.9 | 1.5 | 1.6 | 1.54 |
| Russ Ortiz |   | mr | 32 | 4 | 5 | 1 | 3 | 2 | 0 | 1 | 1 | 0 | 12.3 | 5.7 | 18.4 | 6.3 | 2.6 | 1.1 | 2.00 |
| Chad Orvella |   | mr | 25 | 4 | 1 | 0 | 3 | 1 | 0 | 2 | 1 | 0 | 13.3 | 7.4 | 21.8 | 6.3 | 2.2 | 0.9 | 2.30 |
| Franquelis Osoria |   | mr | 24 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 13.8 | 4.6 | 18.8 | 6.6 | 2.0 | 1.4 | 2.04 |
| Roy Oswalt | BT | sp | 28 | 5 | 6 | 4 | 6 | 1 | 1 | 12 | 4 | 0 | 9.0 | 1.5 | 10.8 | 6.8 | 0.7 | 4.4 | 1.17 |
| Akinori Otsuka | MAD | cl | 34 | 2 | 2 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 8.0 | 1.7 | 9.7 | 7.1 | 0.5 | 4.3 | 1.07 |
| Henry Owens |   | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.0 | 9.0 | 18.0 | 4.5 | 0.0 | 0.5 | 2.00 |
| Vicente Padilla |   | sp | 28 | 8 | 3 | 2 | 17 | 4 | 2 | 6 | 6 | 0 | 9.3 | 3.1 | 13.2 | 7.0 | 0.9 | 2.2 | 1.38 |
| Jonathan Papelbon | BON | cl | 25 | 4 | 1 | 2 | 1 | 2 | 0 | 1 | 2 | 0 | 5.3 | 1.7 | 7.1 | 9.9 | 0.4 | 5.8 | 0.78 |
| Chan Ho Park |   | sp | 33 | 9 | 0 | 7 | 10 | 5 | 0 | 10 | 4 | 0 | 9.6 | 2.9 | 13.2 | 6.3 | 1.3 | 2.2 | 1.39 |
| Chad Paronto | CCL | mr | 30 | 2 | 4 | 3 | 3 | 3 | 0 | 4 | 1 | 0 | 8.4 | 3.0 | 11.9 | 6.5 | 0.8 | 2.2 | 1.27 |
| John Patterson |   | sp | 28 | 8 | 0 | 1 | 3 | 0 | 0 | 2 | 4 | 0 | 8.0 | 2.0 | 10.6 | 9.3 | 0.9 | 4.7 | 1.11 |
| David Pauley |   | sp | 23 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 17.4 | 3.4 | 21.9 | 5.6 | 0.6 | 1.7 | 2.31 |
| Jake Peavy | MUL | sp | 25 | 25 | 6 | 11 | 6 | 4 | 0 | 5 | 1 | 0 | 8.3 | 2.8 | 11.3 | 9.6 | 1.0 | 3.5 | 1.23 |
| Mike Pelfrey |   | sp | 22 | 2 | 1 | 0 | 3 | 2 | 0 | 1 | 1 | 0 | 10.5 | 5.1 | 16.9 | 5.5 | 0.4 | 1.1 | 1.73 |
| Tony Pena |   | mr | 24 | 0 | 1 | 0 | 0 | 1 | 0 | 2 | 1 | 0 | 10.6 | 2.3 | 12.9 | 6.2 | 1.8 | 2.6 | 1.43 |
| Hayden Penn |   | sp | 21 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 17.4 | 5.9 | 24.3 | 3.7 | 3.7 | 0.6 | 2.59 |
| Brad Penny | LON | sp | 28 | 20 | 8 | 4 | 9 | 6 | 0 | 8 | 3 | 0 | 9.8 | 2.6 | 12.8 | 7.0 | 0.9 | 2.7 | 1.38 |
| Joel Peralta |   | mr | 30 | 4 | 1 | 2 | 2 | 5 | 0 | 1 | 3 | 0 | 9.0 | 2.1 | 11.4 | 7.0 | 1.2 | 3.4 | 1.24 |
| Beltran Perez |   | mr | 24 | 4 | 2 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 6.9 | 5.6 | 12.4 | 3.9 | 1.3 | 0.7 | 1.38 |
| Juan Perez* |   | mr | 27 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 13.5 | 2.7 | 21.6 | 8.1 | 2.7 | 3.0 | 1.80 |
| Odalis Perez* |   | sp | 29 | 9 | 3 | 2 | 3 | 6 | 2 | 4 | 7 | 0 | 12.0 | 2.2 | 14.5 | 5.8 | 1.3 | 2.6 | 1.58 |
| Oliver Perez* |   | sp | 24 | 5 | 1 | 0 | 6 | 5 | 1 | 5 | 10 | 0 | 10.3 | 5.4 | 16.2 | 8.1 | 1.6 | 1.5 | 1.75 |
| Rafael Perez* |   | mr | 24 | 3 | 0 | 1 | 0 | 4 | 1 | 1 | 0 | 0 | 7.3 | 4.4 | 11.7 | 10.9 | 1.5 | 2.5 | 1.30 |
| Glen Perkins* |   | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.8 | 0.0 | 4.8 | 9.5 | 0.0 | 99.0 | 0.53 |
| Yusmeiro Petit |   | mr | 21 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 15.7 | 3.1 | 18.8 | 6.8 | 2.4 | 2.2 | 2.09 |
| Andy Pettitte* |   | sp | 34 | 10 | 3 | 9 | 2 | 2 | 1 | 14 | 5 | 0 | 10.0 | 2.9 | 13.0 | 7.5 | 1.1 | 2.5 | 1.44 |
| Joel Pineiro |   | sp | 27 | 8 | 3 | 13 | 10 | 4 | 1 | 1 | 6 | 0 | 11.4 | 3.5 | 15.4 | 4.7 | 1.2 | 1.4 | 1.65 |
| Renyel Pinto* |   | mr | 23 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 1 | 1 | 6.1 | 8.2 | 14.6 | 10.9 | 0.9 | 1.3 | 1.58 |
| Cliff Politte |   | mr | 32 | 3 | 0 | 7 | 1 | 0 | 0 | 0 | 2 | 0 | 14.1 | 4.5 | 18.9 | 4.5 | 2.7 | 1.0 | 2.07 |
| Sidney Ponson |   | sp | 29 | 5 | 3 | 1 | 4 | 2 | 0 | 4 | 0 | 0 | 11.4 | 3.8 | 15.7 | 5.1 | 1.1 | 1.3 | 1.69 |
| Mark Prior |   | sp | 25 | 5 | 2 | 2 | 8 | 5 | 0 | 2 | 2 | 0 | 9.5 | 5.8 | 16.9 | 7.8 | 1.9 | 1.4 | 1.69 |
| Scott Proctor | EDG | mr | 29 | 7 | 2 | 6 | 2 | 2 | 0 | 2 | 6 | 0 | 7.8 | 2.9 | 10.9 | 7.8 | 1.1 | 2.7 | 1.19 |
| J.J. Putz | MID | cl | 29 | 7 | 0 | 1 | 2 | 1 | 0 | 1 | 2 | 0 | 6.8 | 1.5 | 8.5 | 11.9 | 0.5 | 8.0 | 0.92 |
| Chad Qualls | LON | mr | 27 | 3 | 4 | 6 | 6 | 0 | 0 | 4 | 4 | 0 | 7.7 | 2.8 | 11.2 | 5.7 | 1.0 | 2.0 | 1.17 |
| Brad Radke | BON | sp | 33 | 6 | 5 | 3 | 1 | 2 | 0 | 5 | 10 | 0 | 10.9 | 1.8 | 12.8 | 4.6 | 1.3 | 2.6 | 1.41 |
| Elizardo Ramirez |   | sp | 23 | 2 | 3 | 2 | 8 | 0 | 3 | 5 | 3 | 0 | 10.6 | 2.5 | 13.8 | 6.0 | 1.2 | 2.4 | 1.46 |
| Horacio Ramirez* | MUL | sp | 26 | 5 | 1 | 2 | 4 | 0 | 1 | 3 | 3 | 0 | 10.0 | 3.7 | 14.1 | 4.4 | 0.7 | 1.2 | 1.52 |
| Ramon Ramirez | LON | mr | 24 | 2 | 0 | 3 | 1 | 2 | 0 | 2 | 3 | 0 | 7.7 | 3.6 | 11.4 | 8.1 | 0.7 | 2.3 | 1.26 |
| Santiago Ramirez |   | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 16.2 | 5.4 | 21.6 | 2.7 | 2.7 | 0.5 | 2.40 |
| Darrell Rasner |   | sp | 25 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 8.0 | 2.2 | 10.6 | 4.9 | 0.9 | 2.2 | 1.13 |
| Jon Rauch |   | mr | 27 | 8 | 4 | 6 | 2 | 4 | 1 | 1 | 6 | 0 | 7.7 | 3.5 | 11.4 | 8.5 | 1.3 | 2.4 | 1.25 |
| Chris Ray | MID | cl | 24 | 0 | 2 | 2 | 1 | 2 | 0 | 2 | 4 | 0 | 6.1 | 3.7 | 10.0 | 7.0 | 1.4 | 1.9 | 1.09 |
| Ken Ray |   | mr | 31 | 5 | 4 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 8.8 | 5.1 | 13.8 | 6.7 | 1.2 | 1.3 | 1.54 |
| Britt Reames |   | mr | 32 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 13.5 | 6.1 | 19.6 | 7.4 | 2.5 | 1.2 | 2.18 |
| Mark Redman* |   | sp | 32 | 5 | 6 | 1 | 8 | 12 | 2 | 6 | 4 | 0 | 10.9 | 3.4 | 14.7 | 4.1 | 1.0 | 1.2 | 1.59 |
| Chris Reitsma |   | cl | 28 | 1 | 0 | 3 | 3 | 0 | 0 | 3 | 1 | 0 | 14.8 | 2.6 | 18.3 | 4.2 | 2.3 | 1.6 | 1.93 |
| Mike Remlinger* |   | mr | 40 | 0 | 0 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 10.9 | 3.6 | 15.3 | 7.7 | 0.8 | 2.1 | 1.61 |
| Chris Resop |   | mr | 23 | 3 | 1 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 11.0 | 6.8 | 18.1 | 4.2 | 0.4 | 0.6 | 1.97 |
| Anthony Reyes |   | sp | 24 | 5 | 2 | 0 | 7 | 2 | 0 | 5 | 3 | 0 | 8.9 | 3.6 | 13.2 | 7.6 | 1.8 | 2.1 | 1.38 |
| Dennys Reyes* | BON | mr | 29 | 0 | 4 | 2 | 0 | 4 | 0 | 1 | 0 | 0 | 6.2 | 2.7 | 8.9 | 8.7 | 0.5 | 3.3 | 0.99 |
| John Rheinecker* |   | sp | 27 | 2 | 5 | 0 | 3 | 0 | 0 | 1 | 1 | 0 | 13.2 | 2.4 | 16.0 | 3.6 | 0.8 | 1.5 | 1.74 |
| Arthur Rhodes* |   | mr | 36 | 2 | 0 | 7 | 2 | 7 | 0 | 1 | 0 | 1 | 9.3 | 5.9 | 15.6 | 9.5 | 0.4 | 1.6 | 1.69 |
| Juan Rincon | COP | mr | 27 | 3 | 0 | 3 | 3 | 2 | 0 | 5 | 1 | 0 | 9.2 | 2.9 | 12.5 | 7.9 | 0.2 | 2.7 | 1.35 |
| Ricardo Rincon* |   | mr | 36 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 16.2 | 10.8 | 29.7 | 16.2 | 2.7 | 1.5 | 3.00 |
| Royce Ring* |   | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.0 | 2.1 | 7.1 | 5.7 | 1.4 | 2.7 | 0.79 |
| David Riske | CRH | mr | 29 | 3 | 1 | 1 | 3 | 0 | 0 | 1 | 2 | 0 | 8.2 | 3.5 | 12.3 | 5.7 | 1.2 | 1.6 | 1.30 |
| Mariano Rivera | ROK | cl | 36 | 3 | 3 | 4 | 5 | 0 | 0 | 1 | 2 | 0 | 7.3 | 1.3 | 9.2 | 6.6 | 0.4 | 5.0 | 0.96 |
| Saul Rivera |   | mr | 28 | 4 | 0 | 6 | 4 | 3 | 0 | 4 | 1 | 0 | 8.8 | 4.8 | 14.2 | 6.1 | 0.6 | 1.3 | 1.51 |
| Sendy Rleal |   | mr | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 9.3 | 4.4 | 13.7 | 3.7 | 1.9 | 0.8 | 1.52 |
| Nate Robertson* |   | sp | 28 | 9 | 5 | 2 | 8 | 6 | 0 | 4 | 7 | 0 | 8.9 | 2.9 | 12.1 | 5.9 | 1.3 | 2.0 | 1.31 |
| Fernando Rodney | OTR | mr | 29 | 5 | 4 | 4 | 8 | 3 | 0 | 2 | 0 | 0 | 6.4 | 4.3 | 11.7 | 8.2 | 0.8 | 1.9 | 1.19 |
| Eddy Rodriguez |   | mr | 24 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 10.2 | 6.0 | 16.2 | 6.6 | 3.0 | 1.1 | 1.80 |
| Felix Rodriguez |   | mr | 33 | 2 | 1 | 3 | 4 | 1 | 2 | 2 | 3 | 0 | 9.8 | 4.9 | 16.0 | 4.6 | 1.5 | 0.9 | 1.64 |
| Francisco Rodriguez | BON | cl | 24 | 2 | 1 | 5 | 1 | 10 | 0 | 3 | 0 | 0 | 6.4 | 3.5 | 10.0 | 12.1 | 0.7 | 3.5 | 1.10 |
| Wandy Rodriguez* |   | sp | 27 | 6 | 6 | 7 | 6 | 6 | 0 | 7 | 4 | 0 | 10.2 | 4.2 | 14.8 | 6.5 | 1.1 | 1.6 | 1.60 |
| Brian Rogers |   | mr | 23 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 11.4 | 2.1 | 14.5 | 7.3 | 2.1 | 3.5 | 1.50 |
| Kenny Rogers* | EDG | sp | 41 | 1 | 6 | 2 | 9 | 5 | 0 | 1 | 7 | 0 | 8.6 | 2.7 | 11.7 | 4.4 | 1.0 | 1.6 | 1.26 |
| Davis Romero* |   | mr | 23 | 5 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 10.5 | 3.3 | 14.3 | 5.5 | 0.6 | 1.7 | 1.53 |
| J.C. Romero* |   | mr | 30 | 2 | 1 | 2 | 1 | 1 | 0 | 1 | 5 | 0 | 10.6 | 5.2 | 16.0 | 5.8 | 0.6 | 1.1 | 1.76 |
| Matt Roney |   | mr | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 11.3 | 2.3 | 13.5 | 0.0 | 0.0 | 0.0 | 1.50 |
| Francisco Rosario |   | mr | 25 | 8 | 0 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 9.4 | 6.3 | 16.0 | 8.2 | 1.6 | 1.3 | 1.74 |
| Josh Rupe |   | mr | 23 | 1 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 10.2 | 2.8 | 13.3 | 4.3 | 0.6 | 1.6 | 1.45 |
| Glendon Rusch* |   | mr | 31 | 3 | 3 | 2 | 1 | 0 | 0 | 7 | 1 | 0 | 11.7 | 4.5 | 16.3 | 8.0 | 2.8 | 1.8 | 1.79 |
| B.J. Ryan* | MID | cl | 30 | 7 | 3 | 1 | 0 | 4 | 0 | 1 | 1 | 0 | 5.2 | 2.5 | 7.7 | 10.7 | 0.4 | 4.3 | 0.86 |
| Jae Kuk Ryu |   | mr | 23 | 0 | 0 | 1 | 2 | 1 | 0 | 3 | 0 | 0 | 13.8 | 3.6 | 18.6 | 10.2 | 4.2 | 2.8 | 1.93 |
| Kirk Saarloos |   | mr | 27 | 7 | 5 | 3 | 3 | 3 | 0 | 2 | 6 | 0 | 11.1 | 3.9 | 15.2 | 3.9 | 1.4 | 1.0 | 1.66 |
| C.C. Sabathia* | CRH | sp | 25 | 14 | 5 | 3 | 7 | 3 | 0 | 8 | 5 | 0 | 8.5 | 2.1 | 10.9 | 8.0 | 0.8 | 3.9 | 1.17 |
| Billy Sadler |   | mr | 24 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 11.3 | 4.5 | 18.0 | 13.5 | 4.5 | 3.0 | 1.75 |
| Takashi Saito | Pal | cl | 36 | 5 | 0 | 3 | 2 | 2 | 0 | 3 | 4 | 0 | 5.5 | 2.6 | 8.4 | 12.3 | 0.3 | 4.7 | 0.91 |
| Juan Salas |   | mr | 27 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 11.7 | 2.7 | 14.4 | 7.2 | 0.9 | 2.7 | 1.60 |
| Chris Sampson |   | mr | 28 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 6.6 | 1.3 | 8.2 | 4.0 | 0.8 | 3.0 | 0.88 |
| Brian Sanches |   | mr | 27 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 9.7 | 5.5 | 15.2 | 9.3 | 2.1 | 1.7 | 1.69 |
| Anibal Sanchez | MAD | sp | 22 | 6 | 1 | 1 | 4 | 4 | 1 | 3 | 1 | 0 | 7.1 | 3.6 | 11.0 | 5.7 | 0.7 | 1.6 | 1.19 |
| Duaner Sanchez | MAD | mr | 26 | 3 | 0 | 6 | 4 | 1 | 0 | 4 | 4 | 0 | 7.0 | 3.9 | 11.5 | 7.2 | 0.5 | 1.8 | 1.21 |
| Jonathan Sanchez* |   | mr | 23 | 9 | 0 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 8.8 | 5.2 | 14.8 | 7.4 | 0.4 | 1.4 | 1.55 |
| Ervin Santana | BON | sp | 23 | 5 | 9 | 2 | 11 | 10 | 2 | 4 | 10 | 0 | 8.0 | 3.1 | 11.6 | 6.2 | 0.9 | 2.0 | 1.23 |
| Johan Santana* | ROK | sp | 27 | 4 | 5 | 0 | 4 | 4 | 1 | 6 | 4 | 0 | 7.2 | 1.8 | 9.1 | 9.4 | 0.9 | 5.2 | 1.00 |
| Julio Santana |   | mr | 33 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 8.6 | 9.7 | 19.4 | 4.3 | 1.1 | 0.4 | 2.04 |
| Victor Santos |   | sp | 29 | 8 | 4 | 3 | 4 | 5 | 0 | 5 | 4 | 0 | 11.7 | 3.3 | 15.3 | 6.3 | 1.2 | 1.9 | 1.66 |
| Dennis Sarfate |   | mr | 25 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 9.7 | 4.3 | 14.0 | 11.9 | 0.0 | 2.8 | 1.56 |
| Scott Sauerbeck* |   | mr | 34 | 1 | 0 | 1 | 7 | 0 | 0 | 2 | 0 | 0 | 7.8 | 6.4 | 16.7 | 6.0 | 1.1 | 0.9 | 1.58 |
| Joe Saunders* | MID | sp | 25 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 9.0 | 3.7 | 12.9 | 6.5 | 0.8 | 1.8 | 1.42 |
| Curt Schilling | CRH | sp | 39 | 6 | 5 | 1 | 3 | 1 | 0 | 5 | 2 | 0 | 9.7 | 1.2 | 11.1 | 8.1 | 1.2 | 6.5 | 1.22 |
| Jason Schmidt | WIZ | sp | 33 | 12 | 8 | 6 | 6 | 11 | 1 | 7 | 7 | 0 | 8.0 | 3.4 | 11.6 | 7.6 | 0.9 | 2.3 | 1.26 |
| Scott Schoeneweis* |   | mr | 32 | 5 | 1 | 6 | 2 | 3 | 0 | 1 | 0 | 0 | 8.4 | 4.2 | 12.9 | 5.1 | 0.7 | 1.2 | 1.39 |
| Chris Schroder |   | mr | 27 | 2 | 0 | 3 | 5 | 0 | 0 | 1 | 3 | 0 | 7.3 | 4.8 | 13.7 | 12.4 | 2.2 | 2.6 | 1.34 |
| Rudy Seanez |   | mr | 37 | 7 | 0 | 4 | 1 | 7 | 0 | 0 | 1 | 0 | 9.8 | 5.4 | 15.5 | 9.2 | 1.4 | 1.7 | 1.70 |
| Bobby Seay* |   | mr | 28 | 0 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 0 | 8.2 | 5.3 | 15.3 | 7.0 | 0.6 | 1.3 | 1.50 |
| Aaron Sele |   | sp | 36 | 6 | 2 | 2 | 2 | 3 | 0 | 4 | 1 | 0 | 10.5 | 2.6 | 13.2 | 5.0 | 1.0 | 1.9 | 1.45 |
| Jae Seo |   | sp | 29 | 5 | 7 | 4 | 4 | 5 | 1 | 6 | 8 | 0 | 11.3 | 3.2 | 14.7 | 5.0 | 1.8 | 1.6 | 1.61 |
| Brian Shackelford* |   | mr | 29 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 9.9 | 5.5 | 16.5 | 8.3 | 2.2 | 1.5 | 1.71 |
| Josh Sharpless |   | mr | 25 | 5 | 1 | 1 | 0 | 2 | 0 | 1 | 1 | 0 | 5.3 | 8.3 | 13.5 | 5.3 | 0.0 | 0.6 | 1.50 |
| Ben Sheets | TON | sp | 27 | 10 | 2 | 1 | 2 | 3 | 0 | 6 | 5 | 0 | 8.9 | 0.9 | 10.0 | 9.8 | 0.8 | 10.5 | 1.09 |
| George Sherrill* | ROK | mr | 29 | 4 | 2 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 6.8 | 6.1 | 12.8 | 9.4 | 0.0 | 1.6 | 1.42 |
| James Shields | BON | sp | 24 | 7 | 4 | 5 | 5 | 9 | 0 | 4 | 3 | 0 | 10.2 | 2.7 | 13.3 | 7.5 | 1.3 | 2.7 | 1.44 |
| Scot Shields | ROK | mr | 30 | 10 | 0 | 4 | 1 | 8 | 0 | 3 | 1 | 0 | 7.2 | 2.5 | 9.8 | 8.6 | 0.8 | 3.5 | 1.07 |
| Jason Shiell |   | sp | 29 | 1 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 0 | 13.2 | 5.2 | 19.0 | 8.0 | 2.9 | 1.6 | 2.04 |
| Brian Shouse* | OTR | mr | 37 | 2 | 2 | 5 | 6 | 0 | 0 | 1 | 1 | 0 | 9.4 | 4.2 | 15.0 | 5.4 | 0.9 | 1.3 | 1.51 |
| Brian Sikorski |   | mr | 31 | 3 | 2 | 1 | 1 | 3 | 0 | 1 | 1 | 0 | 9.5 | 1.9 | 11.6 | 10.1 | 2.1 | 5.4 | 1.26 |
| Carlos Silva |   | sp | 27 | 10 | 2 | 4 | 7 | 1 | 0 | 6 | 7 | 0 | 12.3 | 1.6 | 14.2 | 3.5 | 1.9 | 2.2 | 1.54 |
| Allan Simpson |   | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.4 | 13.5 | 16.9 | 16.9 | 0.0 | 1.3 | 1.88 |
| Andrew Sisco* |   | mr | 23 | 5 | 1 | 6 | 1 | 4 | 0 | 4 | 5 | 0 | 10.2 | 6.2 | 16.5 | 8.0 | 1.2 | 1.3 | 1.82 |
| Doug Slaten* |   | mr | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 4.8 | 3.2 | 7.9 | 4.8 | 0.0 | 1.5 | 0.88 |
| Brian Slocum |   | mr | 25 | 1 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 13.8 | 4.6 | 18.8 | 5.6 | 1.5 | 1.2 | 2.04 |
| Aaron Small |   | mr | 34 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 13.7 | 3.9 | 17.9 | 3.9 | 2.9 | 1.0 | 1.95 |
| Matt Smith* |   | mr | 27 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.0 | 5.2 | 8.3 | 9.1 | 0.0 | 1.8 | 0.92 |
| Mike Smith |   | sp | 28 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 15.0 | 9.0 | 27.0 | 3.0 | 3.0 | 0.3 | 2.67 |
| Travis Smith |   | sp | 33 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 10.4 | 2.1 | 12.5 | 2.1 | 0.0 | 1.0 | 1.38 |
| John Smoltz | WIZ | sp | 39 | 10 | 4 | 4 | 9 | 5 | 0 | 4 | 10 | 0 | 8.6 | 2.1 | 11.1 | 8.2 | 0.9 | 3.8 | 1.19 |
| Ian Snell |   | sp | 24 | 16 | 5 | 4 | 2 | 8 | 0 | 16 | 6 | 0 | 9.6 | 3.6 | 13.3 | 8.2 | 1.4 | 2.3 | 1.46 |
| Kyle Snyder |   | sp | 28 | 6 | 2 | 3 | 2 | 3 | 0 | 0 | 2 | 0 | 13.0 | 3.0 | 16.3 | 8.5 | 1.8 | 2.8 | 1.77 |
| Alay Soler |   | sp | 26 | 5 | 0 | 1 | 1 | 3 | 0 | 2 | 2 | 0 | 10.0 | 4.2 | 14.4 | 4.6 | 1.4 | 1.1 | 1.58 |
| Rafael Soriano | GEO | mr | 26 | 7 | 2 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 6.6 | 3.1 | 10.0 | 9.8 | 0.9 | 3.1 | 1.08 |
| Jorge Sosa |   | mr | 29 | 2 | 2 | 6 | 1 | 2 | 0 | 7 | 4 | 0 | 10.5 | 3.1 | 13.7 | 5.7 | 2.3 | 1.9 | 1.51 |
| Jeremy Sowers* | EDG | sp | 23 | 6 | 3 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 8.7 | 2.0 | 10.9 | 3.6 | 1.0 | 1.8 | 1.19 |
| Justin Speier | MID | mr | 32 | 9 | 1 | 3 | 1 | 4 | 0 | 0 | 0 | 0 | 8.2 | 3.7 | 12.1 | 9.6 | 0.9 | 2.6 | 1.32 |
| Russ Springer | WIZ | mr | 37 | 7 | 1 | 1 | 4 | 2 | 0 | 2 | 0 | 0 | 6.9 | 2.4 | 10.0 | 6.9 | 1.5 | 2.9 | 1.04 |
| Chris Spurling |   | mr | 29 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 10.5 | 3.4 | 13.9 | 3.0 | 2.1 | 0.9 | 1.55 |
| Jason Standridge |   | mr | 27 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 8.2 | 6.8 | 15.4 | 8.7 | 1.0 | 1.3 | 1.66 |
| Mike Stanton* |   | mr | 39 | 4 | 4 | 11 | 2 | 5 | 1 | 2 | 4 | 0 | 9.3 | 3.6 | 13.2 | 6.4 | 0.3 | 1.8 | 1.43 |
| Tim Stauffer | MAD | sp | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 1.5 | 6.0 | 3.0 | 0.0 | 2.0 | 0.67 |
| Steve Stemle |   | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 22.5 | 4.5 | 27.0 | 0.0 | 1.5 | 0.0 | 3.00 |
| Phil Stockman |   | mr | 26 | 2 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 6.8 | 9.0 | 15.8 | 9.0 | 0.0 | 1.0 | 1.75 |
| Brian Stokes |   | sp | 26 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 11.6 | 3.4 | 15.4 | 5.6 | 0.8 | 1.7 | 1.67 |
| Huston Street | GEO | cl | 22 | 5 | 1 | 3 | 2 | 4 | 0 | 3 | 3 | 0 | 8.2 | 1.7 | 10.1 | 8.5 | 0.5 | 5.2 | 1.09 |
| Eric Stults* |   | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 8.7 | 3.6 | 12.2 | 2.5 | 2.0 | 0.7 | 1.36 |
| Tanyon Sturtze |   | mr | 35 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 14.3 | 5.1 | 20.3 | 5.1 | 2.5 | 1.0 | 2.16 |
| Jeff Suppan |   | sp | 31 | 12 | 3 | 6 | 8 | 8 | 0 | 9 | 3 | 1 | 9.8 | 3.3 | 13.5 | 4.9 | 1.0 | 1.5 | 1.45 |
| Brian Sweeney | MUL | mr | 32 | 3 | 0 | 5 | 1 | 2 | 0 | 5 | 2 | 0 | 8.5 | 2.6 | 11.2 | 3.7 | 1.0 | 1.4 | 1.22 |
| Jon Switzer* |   | mr | 26 | 1 | 1 | 3 | 1 | 3 | 0 | 2 | 1 | 0 | 10.2 | 5.1 | 15.5 | 4.8 | 1.3 | 0.9 | 1.69 |
| Brian Tallet* |   | mr | 28 | 4 | 4 | 4 | 3 | 2 | 1 | 1 | 5 | 0 | 7.5 | 5.1 | 13.1 | 6.1 | 0.8 | 1.2 | 1.40 |
| Taylor Tankersley* | MAD | mr | 23 | 1 | 0 | 5 | 1 | 3 | 0 | 3 | 3 | 0 | 7.2 | 5.7 | 13.2 | 10.1 | 0.9 | 1.8 | 1.44 |
| Jack Taschner* |   | mr | 28 | 2 | 1 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 14.4 | 3.3 | 18.6 | 7.0 | 1.9 | 2.1 | 1.97 |
| Jordan Tata |   | mr | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 8.6 | 4.3 | 12.9 | 3.7 | 0.6 | 0.9 | 1.43 |
| Ty Taubenheim |   | sp | 23 | 3 | 0 | 0 | 4 | 1 | 0 | 1 | 2 | 0 | 10.3 | 4.6 | 15.9 | 6.7 | 1.3 | 1.4 | 1.66 |
| Julian Tavarez |   | mr | 33 | 2 | 0 | 3 | 6 | 2 | 0 | 3 | 3 | 0 | 10.0 | 4.0 | 14.6 | 5.1 | 0.9 | 1.3 | 1.56 |
| Robinson Tejeda |   | sp | 24 | 4 | 3 | 1 | 3 | 1 | 1 | 1 | 5 | 0 | 10.1 | 3.9 | 14.4 | 4.9 | 1.2 | 1.3 | 1.56 |
| Brad Thompson |   | mr | 24 | 1 | 1 | 3 | 5 | 1 | 0 | 3 | 0 | 0 | 9.2 | 3.2 | 13.2 | 5.1 | 0.6 | 1.6 | 1.38 |
| Mike Thompson |   | sp | 25 | 6 | 0 | 4 | 7 | 1 | 0 | 5 | 2 | 0 | 10.1 | 2.9 | 13.7 | 3.4 | 1.3 | 1.2 | 1.45 |
| John Thomson |   | sp | 32 | 11 | 4 | 4 | 2 | 1 | 0 | 5 | 7 | 0 | 10.4 | 3.6 | 14.2 | 5.2 | 1.2 | 1.4 | 1.56 |
| Matt Thornton* | CRH | mr | 29 | 4 | 0 | 4 | 1 | 1 | 0 | 1 | 3 | 0 | 7.7 | 3.5 | 11.3 | 8.2 | 0.8 | 2.3 | 1.24 |
| Mike Timlin | OTR | mr | 40 | 4 | 1 | 4 | 2 | 3 | 0 | 4 | 1 | 0 | 11.0 | 2.3 | 13.5 | 4.2 | 1.0 | 1.9 | 1.47 |
| Brett Tomko |   | mr | 33 | 4 | 1 | 0 | 2 | 3 | 1 | 7 | 7 | 0 | 9.9 | 2.3 | 12.3 | 6.1 | 1.4 | 2.6 | 1.35 |
| Salomon Torres | CCL | mr | 34 | 5 | 3 | 9 | 6 | 3 | 0 | 7 | 2 | 0 | 9.4 | 3.7 | 13.7 | 6.9 | 0.6 | 1.9 | 1.46 |
| Josh Towers |   | sp | 29 | 12 | 2 | 3 | 3 | 1 | 1 | 1 | 3 | 0 | 13.5 | 2.5 | 16.4 | 5.1 | 2.5 | 2.1 | 1.77 |
| Billy Traber* |   | sp | 26 | 3 | 2 | 2 | 8 | 0 | 0 | 3 | 1 | 0 | 11.0 | 2.9 | 15.6 | 5.2 | 1.0 | 1.8 | 1.55 |
| Sean Tracey |   | mr | 25 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 4.5 | 5.6 | 11.3 | 3.4 | 2.3 | 0.6 | 1.13 |
| Steve Trachsel |   | sp | 35 | 12 | 7 | 1 | 4 | 4 | 0 | 4 | 7 | 0 | 10.1 | 4.3 | 14.6 | 4.3 | 1.3 | 1.0 | 1.60 |
| Derrick Turnbow |   | cl | 28 | 3 | 1 | 2 | 4 | 6 | 1 | 2 | 1 | 0 | 8.9 | 6.2 | 15.8 | 11.0 | 1.3 | 1.8 | 1.69 |
| Jose Valverde | WIZ | cl | 26 | 1 | 0 | 3 | 2 | 2 | 0 | 1 | 3 | 0 | 9.1 | 4.0 | 13.5 | 12.6 | 1.1 | 3.1 | 1.46 |
| Jermaine Van Buren |   | mr | 25 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 9.7 | 10.4 | 20.1 | 5.5 | 0.7 | 0.5 | 2.23 |
| Claudio Vargas |   | sp | 28 | 12 | 5 | 2 | 8 | 9 | 1 | 8 | 3 | 0 | 9.9 | 2.8 | 13.2 | 6.6 | 1.4 | 2.4 | 1.41 |
| Jason Vargas* |   | mr | 23 | 6 | 0 | 3 | 4 | 2 | 0 | 4 | 4 | 0 | 10.5 | 6.3 | 17.6 | 5.2 | 1.9 | 0.8 | 1.86 |
| Javier Vazquez | Pal | sp | 29 | 10 | 4 | 2 | 15 | 7 | 0 | 2 | 4 | 0 | 9.1 | 2.5 | 12.3 | 8.2 | 1.0 | 3.3 | 1.29 |
| Mike Venafro* |   | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.4 | 7.4 | 14.7 | 4.9 | 0.0 | 0.7 | 1.64 |
| Jose Veras |   | mr | 25 | 2 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 6.5 | 4.1 | 10.6 | 4.9 | 1.6 | 1.2 | 1.18 |
| Justin Verlander | COP | sp | 23 | 1 | 5 | 1 | 6 | 5 | 1 | 2 | 4 | 1 | 9.0 | 2.9 | 12.2 | 6.0 | 1.0 | 2.1 | 1.33 |
| Carlos Villanueva | TON | sp | 22 | 2 | 0 | 1 | 4 | 0 | 0 | 1 | 0 | 0 | 7.2 | 1.8 | 9.7 | 6.5 | 1.3 | 3.5 | 1.01 |
| Oscar Villarreal |   | mr | 24 | 4 | 1 | 3 | 5 | 4 | 0 | 5 | 4 | 0 | 9.1 | 2.6 | 12.2 | 5.4 | 1.3 | 2.0 | 1.30 |
| Ron Villone* |   | mr | 36 | 1 | 3 | 9 | 4 | 5 | 0 | 6 | 4 | 0 | 8.4 | 5.7 | 14.6 | 8.1 | 1.0 | 1.4 | 1.57 |
| Luis Vizcaino | LON | mr | 31 | 2 | 2 | 6 | 4 | 1 | 0 | 2 | 0 | 0 | 7.0 | 4.0 | 11.6 | 9.9 | 1.1 | 2.5 | 1.22 |
| Ryan Vogelsong |   | mr | 28 | 6 | 1 | 2 | 7 | 4 | 1 | 5 | 4 | 0 | 10.4 | 3.8 | 15.9 | 6.4 | 0.5 | 1.7 | 1.58 |
| Edinson Volquez |   | sp | 22 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 14.0 | 4.6 | 18.9 | 4.0 | 1.9 | 0.9 | 2.07 |
| Doug Waechter |   | sp | 25 | 1 | 2 | 1 | 5 | 0 | 0 | 3 | 6 | 0 | 11.4 | 3.2 | 15.5 | 4.2 | 1.0 | 1.3 | 1.62 |
| Billy Wagner* | BT | cl | 34 | 5 | 4 | 1 | 4 | 2 | 0 | 2 | 0 | 0 | 7.3 | 2.6 | 10.5 | 11.7 | 0.9 | 4.5 | 1.11 |
| Ryan Wagner |   | mr | 23 | 3 | 0 | 3 | 2 | 3 | 1 | 1 | 0 | 0 | 10.6 | 4.4 | 15.6 | 5.9 | 0.9 | 1.3 | 1.66 |
| Adam Wainwright | MAD | mr | 24 | 3 | 0 | 2 | 4 | 3 | 0 | 4 | 1 | 0 | 7.7 | 2.6 | 10.8 | 8.6 | 0.7 | 3.3 | 1.15 |
| Tim Wakefield | OTR | sp | 39 | 24 | 4 | 0 | 10 | 6 | 0 | 1 | 3 | 0 | 8.7 | 3.3 | 12.6 | 5.8 | 1.2 | 1.8 | 1.33 |
| Jamie Walker* | OTR | mr | 34 | 2 | 1 | 3 | 0 | 1 | 0 | 1 | 0 | 0 | 8.8 | 1.5 | 10.3 | 6.9 | 1.5 | 4.6 | 1.15 |
| Pete Walker |   | mr | 37 | 3 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 11.1 | 3.9 | 15.0 | 8.1 | 1.5 | 2.1 | 1.67 |
| Tyler Walker |   | cl | 30 | 4 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 9.6 | 4.3 | 13.9 | 6.8 | 0.4 | 1.6 | 1.54 |
| Les Walrond* |   | mr | 29 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 9.9 | 6.2 | 16.1 | 10.9 | 1.0 | 1.8 | 1.79 |
| Chien-Ming Wang | COP | sp | 26 | 9 | 11 | 4 | 2 | 6 | 1 | 3 | 2 | 0 | 9.6 | 2.1 | 11.8 | 3.1 | 0.5 | 1.5 | 1.31 |
| John Wasdin |   | sp | 33 | 2 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 9.9 | 3.9 | 15.0 | 4.8 | 1.8 | 1.2 | 1.53 |
| Jarrod Washburn* |   | sp | 31 | 5 | 5 | 2 | 7 | 3 | 0 | 3 | 6 | 0 | 9.5 | 2.6 | 12.5 | 5.0 | 1.2 | 1.9 | 1.35 |
| David Weathers | TON | mr | 36 | 3 | 1 | 4 | 2 | 0 | 0 | 5 | 3 | 0 | 7.5 | 4.2 | 11.9 | 6.1 | 1.5 | 1.5 | 1.29 |
| Jeff Weaver |   | sp | 29 | 9 | 8 | 1 | 10 | 5 | 0 | 7 | 4 | 0 | 11.1 | 2.5 | 14.1 | 5.6 | 1.8 | 2.3 | 1.51 |
| Jered Weaver | OTR | sp | 23 | 11 | 3 | 1 | 3 | 2 | 0 | 2 | 2 | 0 | 6.9 | 2.4 | 9.5 | 7.7 | 1.1 | 3.2 | 1.03 |
| Brandon Webb | TON | sp | 27 | 24 | 9 | 4 | 6 | 5 | 2 | 10 | 6 | 0 | 8.3 | 1.9 | 10.4 | 6.8 | 0.6 | 3.6 | 1.13 |
| Todd Wellemeyer |   | mr | 27 | 6 | 1 | 3 | 4 | 9 | 0 | 3 | 6 | 0 | 7.8 | 5.7 | 14.0 | 6.2 | 0.7 | 1.1 | 1.51 |
| David Wells* | EDG | sp | 43 | 7 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 11.6 | 1.4 | 13.0 | 4.5 | 1.3 | 3.2 | 1.45 |
| Kip Wells |   | sp | 29 | 2 | 4 | 1 | 4 | 5 | 0 | 1 | 1 | 0 | 12.4 | 4.3 | 17.5 | 4.1 | 0.6 | 1.0 | 1.85 |
| Jake Westbrook | MID | sp | 28 | 16 | 3 | 4 | 4 | 5 | 0 | 5 | 4 | 1 | 10.5 | 2.3 | 13.0 | 4.6 | 0.6 | 2.0 | 1.43 |
| Dan Wheeler | Pal | mr | 28 | 3 | 1 | 8 | 2 | 0 | 0 | 3 | 3 | 0 | 7.3 | 3.0 | 10.6 | 8.6 | 0.6 | 2.8 | 1.15 |
| Rick White |   | mr | 37 | 3 | 2 | 1 | 3 | 4 | 2 | 5 | 2 | 0 | 10.0 | 2.8 | 13.2 | 5.6 | 1.1 | 2.0 | 1.42 |
| Bob Wickman | COP | cl | 37 | 4 | 0 | 0 | 1 | 1 | 0 | 5 | 3 | 0 | 8.8 | 2.2 | 11.2 | 7.0 | 0.3 | 3.2 | 1.22 |
| Dave Williams* |   | sp | 27 | 2 | 4 | 1 | 6 | 2 | 1 | 6 | 3 | 0 | 12.1 | 2.6 | 15.5 | 4.2 | 1.8 | 1.6 | 1.64 |
| Jerome Williams |   | mr | 24 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 3 | 0 | 10.9 | 8.0 | 19.7 | 3.6 | 1.5 | 0.5 | 2.11 |
| Todd Williams |   | mr | 35 | 2 | 1 | 3 | 2 | 6 | 0 | 3 | 1 | 0 | 12.0 | 3.0 | 15.3 | 3.8 | 1.3 | 1.3 | 1.67 |
| Woody Williams | MUL | sp | 39 | 10 | 0 | 3 | 7 | 4 | 1 | 7 | 5 | 0 | 9.4 | 2.2 | 12.0 | 4.5 | 1.3 | 2.1 | 1.29 |
| Scott Williamson |   | mr | 30 | 14 | 3 | 1 | 1 | 8 | 1 | 0 | 2 | 0 | 9.4 | 5.0 | 14.6 | 9.6 | 0.9 | 1.9 | 1.60 |
| Dontrelle Willis* | MAD | sp | 24 | 6 | 5 | 6 | 19 | 6 | 1 | 11 | 6 | 1 | 9.4 | 3.3 | 13.5 | 6.4 | 0.8 | 1.9 | 1.42 |
| Brian Wilson |   | mr | 24 | 2 | 2 | 2 | 1 | 0 | 0 | 1 | 4 | 0 | 9.6 | 6.3 | 16.2 | 6.9 | 0.3 | 1.1 | 1.77 |
| C.J. Wilson* | ROK | mr | 25 | 5 | 3 | 1 | 5 | 0 | 0 | 1 | 0 | 0 | 7.9 | 3.7 | 12.6 | 8.7 | 1.4 | 2.4 | 1.29 |
| Kris Wilson |   | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.1 | 4.3 | 19.4 | 6.5 | 4.3 | 1.5 | 2.16 |
| Jason Windsor |   | sp | 23 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 13.8 | 3.3 | 17.1 | 4.0 | 1.3 | 1.2 | 1.90 |
| Joe Winkelsas |   | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.6 | 7.7 | 19.3 | 5.1 | 1.3 | 0.7 | 2.14 |
| Matt Wise |   | mr | 30 | 1 | 1 | 2 | 2 | 0 | 1 | 3 | 1 | 0 | 9.1 | 2.8 | 12.4 | 5.5 | 1.2 | 1.9 | 1.33 |
| Jay Witasick |   | mr | 33 | 1 | 0 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 9.9 | 8.3 | 18.7 | 9.1 | 1.2 | 1.1 | 2.03 |
| Randy Wolf* |   | sp | 29 | 3 | 2 | 2 | 2 | 2 | 0 | 2 | 3 | 0 | 10.0 | 5.2 | 15.6 | 7.0 | 2.1 | 1.3 | 1.69 |
| Kerry Wood | MUL | sp | 29 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 8.7 | 3.7 | 12.8 | 5.9 | 2.3 | 1.6 | 1.37 |
| Mike Wood |   | mr | 26 | 0 | 2 | 3 | 7 | 3 | 0 | 1 | 2 | 0 | 12.0 | 3.2 | 16.1 | 4.0 | 1.4 | 1.3 | 1.69 |
| Jake Woods* |   | mr | 24 | 4 | 2 | 5 | 2 | 4 | 0 | 2 | 2 | 0 | 9.9 | 4.5 | 14.6 | 5.7 | 1.0 | 1.2 | 1.60 |
| Tim Worrell |   | cl | 38 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 12.4 | 3.1 | 15.9 | 5.3 | 4.0 | 1.7 | 1.72 |
| Jamey Wright |   | sp | 31 | 13 | 8 | 4 | 10 | 6 | 0 | 5 | 4 | 0 | 9.6 | 3.7 | 13.9 | 4.6 | 0.9 | 1.2 | 1.48 |
| Jaret Wright |   | sp | 30 | 3 | 4 | 0 | 7 | 6 | 0 | 3 | 3 | 0 | 10.1 | 3.7 | 14.2 | 5.4 | 0.6 | 1.5 | 1.52 |
| Michael Wuertz | BT | mr | 27 | 4 | 0 | 2 | 1 | 1 | 0 | 3 | 0 | 0 | 7.7 | 3.5 | 11.5 | 9.3 | 1.1 | 2.6 | 1.25 |
| Esteban Yan |   | mr | 31 | 2 | 2 | 4 | 1 | 5 | 0 | 2 | 3 | 0 | 7.7 | 4.8 | 12.8 | 5.8 | 1.9 | 1.2 | 1.39 |
| Tyler Yates | TON | mr | 28 | 2 | 0 | 8 | 0 | 1 | 0 | 2 | 0 | 0 | 7.6 | 5.6 | 13.1 | 8.3 | 1.1 | 1.5 | 1.46 |
| Shane Youman* |   | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 6.2 | 4.2 | 10.4 | 2.1 | 0.4 | 0.5 | 1.15 |
| Chris Young | COP | sp | 27 | 41 | 4 | 4 | 6 | 6 | 1 | 8 | 3 | 0 | 6.7 | 3.5 | 10.5 | 8.2 | 1.4 | 2.4 | 1.13 |
| Carlos Zambrano | CCL | sp | 25 | 2 | 3 | 4 | 9 | 9 | 1 | 11 | 4 | 0 | 6.8 | 4.8 | 12.0 | 8.8 | 0.8 | 1.8 | 1.29 |
| Victor Zambrano |   | sp | 30 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.5 | 4.6 | 15.2 | 6.3 | 2.1 | 1.4 | 1.69 |
| Barry Zito* | EDG | sp | 28 | 8 | 12 | 5 | 13 | 4 | 2 | 7 | 6 | 0 | 8.6 | 4.0 | 13.2 | 6.1 | 1.1 | 1.5 | 1.40 |
| Joel Zumaya | ROK | mr | 21 | 4 | 1 | 2 | 2 | 4 | 0 | 2 | 4 | 0 | 6.0 | 4.5 | 10.8 | 10.5 | 0.6 | 2.3 | 1.18 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | BT | mr | 24 | .693 | 138 | .232 | 101 | .449 | 102 | .453 | 25.8 | 4.4 | 3.94 | 3.88 |
| Winston Abreu |   | mr | 29 | .964 | 28 | .321 | 25 | .595 | 26 | .619 | 8.5 | 9.2 | 8.64 | 7.17 |
| Jeremy Accardo |   | mr | 24 | .748 | 215 | .321 | 134 | .451 | 135 | .455 | 38.8 | 5.1 | 4.55 | 4.17 |
| Mike Adams | MUL | mr | 27 | 1.189 | 9 | .333 | 10 | .769 | 10 | .769 | 4.2 | 16.1 | 14.48 | 13.74 |
| Jon Adkins |   | mr | 28 | .733 | 177 | .294 | 100 | .431 | 102 | .440 | 26.2 | 4.3 | 3.90 | 3.77 |
| Jeremy Affeldt* | CRH | mr | 27 | .778 | 330 | .270 | 216 | .482 | 218 | .487 | 61.8 | 5.6 | 5.14 | 5.21 |
| Matt Albers |   | sp | 23 | .796 | 47 | .340 | 31 | .470 | 31 | .470 | 8.7 | 5.2 | 4.70 | 4.97 |
| Antonio Alfonseca |   | mr | 34 | .951 | 59 | .339 | 43 | .581 | 43 | .581 | 13.5 | 7.6 | 6.82 | 7.86 |
| Abe Alvarez* |   | mr | 23 | 1.390 | 9 | .333 | 14 | .933 | 14 | .933 | 5.0 | 15.0 | 13.52 | 15.67 |
| Steve Andrade |   | mr | 28 | .687 | 14 | .357 | 9 | .391 | 9 | .391 | 2.8 | 5.3 | 4.81 | 5.35 |
| Greg Aquino |   | mr | 28 | .840 | 133 | .346 | 113 | .514 | 117 | .532 | 32.9 | 6.1 | 5.52 | 5.99 |
| Tony Armas |   | sp | 28 | .800 | 500 | .296 | 328 | .473 | 341 | .492 | 97.8 | 5.7 | 5.14 | 5.04 |
| Bronson Arroyo | BT | sp | 29 | .693 | 708 | .270 | 426 | .429 | 431 | .434 | 106.0 | 4.0 | 3.57 | 3.37 |
| Miguel Asencio |   | mr | 25 | .878 | 24 | .333 | 20 | .541 | 21 | .568 | 6.3 | 7.0 | 6.61 | 6.23 |
| Ezequiel Astacio |   | mr | 26 | 1.017 | 16 | .313 | 20 | .667 | 20 | .667 | 6.6 | 10.5 | 9.48 | 9.34 |
| Pedro Astacio |   | sp | 36 | .859 | 319 | .298 | 214 | .526 | 215 | .528 | 65.6 | 6.5 | 5.89 | 5.38 |
| Brandon Backe |   | sp | 28 | .746 | 145 | .269 | 85 | .450 | 88 | .466 | 23.5 | 4.9 | 4.43 | 4.37 |
| Cha Seung Baek |   | sp | 26 | .677 | 96 | .208 | 61 | .436 | 63 | .450 | 14.6 | 3.9 | 3.45 | 3.44 |
| Danys Baez |   | mr | 28 | .716 | 191 | .298 | 103 | .401 | 110 | .428 | 29.6 | 4.4 | 4.02 | 3.69 |
| Jeff Bajenaru |   | mr | 28 | 2.429 | 4 | .250 | 13 | 1.857 | 13 | 1.857 | 7.4 | 66.9 | 60.17 | 60.11 |
| Scott Baker |   | sp | 24 | .909 | 279 | .348 | 211 | .560 | 214 | .568 | 68.6 | 7.4 | 6.67 | 6.26 |
| Brian Bannister |   | sp | 25 | .736 | 124 | .242 | 78 | .456 | 80 | .468 | 22.3 | 5.2 | 4.74 | 4.27 |
| Kevin Barry |   | mr | 27 | .790 | 79 | .278 | 56 | .487 | 57 | .496 | 17.3 | 6.2 | 5.47 | 4.21 |
| Phil Barzilla* |   | mr | 27 | 1.000 | 2 | .500 | 1 | .500 | 1 | .500 | 0.5 | 13.5 | 12.15 | 14.52 |
| Miguel Batista |   | sp | 35 | .783 | 692 | .308 | 426 | .468 | 432 | .475 | 118.0 | 5.1 | 4.63 | 4.82 |
| Rick Bauer | EDG | mr | 29 | .718 | 234 | .295 | 127 | .421 | 131 | .434 | 33.3 | 4.2 | 3.80 | 4.04 |
| Denny Bautista |   | sp | 23 | .831 | 137 | .307 | 97 | .500 | 101 | .521 | 29.8 | 6.4 | 5.80 | 5.75 |
| Jonah Bayliss |   | mr | 25 | .706 | 41 | .293 | 29 | .420 | 30 | .435 | 8.4 | 5.2 | 4.64 | 4.46 |
| T.J. Beam |   | mr | 25 | 1.114 | 60 | .350 | 61 | .718 | 63 | .741 | 21.5 | 10.9 | 9.67 | 8.36 |
| Colter Bean |   | mr | 29 | 1.000 | 6 | .333 | 5 | .500 | 6 | .600 | 1.9 | 8.7 | 7.81 | 8.25 |
| Josh Beckett | Pal | sp | 26 | .767 | 591 | .262 | 425 | .489 | 435 | .501 | 111.9 | 4.9 | 4.43 | 4.28 |
| Erik Bedard* | GEO | sp | 27 | .692 | 583 | .309 | 350 | .415 | 355 | .421 | 91.5 | 4.2 | 3.77 | 3.83 |
| Joe Beimel* |   | mr | 29 | .725 | 237 | .266 | 131 | .444 | 131 | .444 | 31.3 | 3.9 | 3.62 | 3.62 |
| Matt Belisle |   | mr | 26 | .789 | 127 | .299 | 85 | .472 | 88 | .489 | 24.5 | 5.5 | 4.96 | 5.29 |
| Heath Bell | MUL | mr | 28 | .869 | 114 | .395 | 87 | .524 | 87 | .524 | 26.0 | 6.3 | 5.69 | 6.40 |
| Armando Benitez |   | cl | 33 | .784 | 113 | .292 | 84 | .491 | 84 | .491 | 24.4 | 5.8 | 5.15 | 5.11 |
| Joaquin Benoit | OTR | mr | 28 | .624 | 216 | .292 | 132 | .380 | 135 | .389 | 32.0 | 3.6 | 3.25 | 3.30 |
| Kris Benson |   | sp | 31 | .828 | 595 | .279 | 395 | .506 | 402 | .515 | 113.6 | 5.7 | 5.03 | 5.06 |
| Jason Bergmann |   | mr | 24 | .949 | 204 | .338 | 174 | .574 | 180 | .594 | 59.0 | 8.3 | 7.40 | 6.50 |
| Adam Bernero |   | sp | 29 | .929 | 51 | .373 | 40 | .588 | 40 | .588 | 13.2 | 7.9 | 7.13 | 6.43 |
| Rafael Betancourt | GEO | mr | 31 | .664 | 165 | .273 | 95 | .411 | 95 | .411 | 23.4 | 3.7 | 3.35 | 2.84 |
| Chad Billingsley | TON | sp | 21 | .768 | 276 | .308 | 188 | .467 | 191 | .474 | 50.5 | 5.1 | 4.55 | 5.22 |
| Kurt Birkins* |   | mr | 25 | .691 | 86 | .244 | 57 | .419 | 60 | .441 | 14.5 | 4.1 | 3.78 | 3.98 |
| Joe Blanton | BON | sp | 25 | .805 | 669 | .335 | 408 | .477 | 413 | .482 | 123.3 | 5.8 | 5.14 | 5.09 |
| Jeremy Bonderman | OTR | sp | 23 | .717 | 616 | .318 | 399 | .442 | 402 | .445 | 104.0 | 4.4 | 3.94 | 3.58 |
| Boof Bonser | BON | sp | 24 | .771 | 292 | .295 | 204 | .487 | 205 | .489 | 53.2 | 4.8 | 4.30 | 4.25 |
| Chris Booker |   | mr | 29 | 1.074 | 23 | .261 | 28 | .737 | 28 | .737 | 8.7 | 9.4 | 8.50 | 8.66 |
| Chris Bootcheck |   | mr | 27 | 1.131 | 35 | .371 | 38 | .704 | 38 | .704 | 12.4 | 10.1 | 9.71 | 11.63 |
| Dave Borkowski |   | mr | 29 | .754 | 216 | .287 | 143 | .478 | 143 | .478 | 37.3 | 4.8 | 4.26 | 3.65 |
| Joe Borowski |   | cl | 35 | .700 | 198 | .283 | 134 | .441 | 136 | .447 | 34.3 | 4.4 | 3.99 | 3.74 |
| Micah Bowie* |   | mr | 31 | .497 | 56 | .179 | 24 | .320 | 24 | .320 | 4.4 | 2.0 | 1.81 | 1.54 |
| Blaine Boyer |   | mr | 24 | 1.381 | 6 | .667 | 5 | .714 | 5 | .714 | 3.0 | 41.1 | 36.97 | 47.92 |
| Chad Bradford | EDG | mr | 31 | .618 | 193 | .301 | 89 | .353 | 89 | .353 | 21.9 | 3.2 | 2.86 | 2.48 |
| Ryan Braun |   | mr | 25 | .941 | 35 | .314 | 27 | .587 | 27 | .587 | 7.9 | 6.6 | 5.97 | 5.63 |
| Bill Bray* |   | mr | 23 | .767 | 160 | .325 | 103 | .462 | 104 | .466 | 27.8 | 4.8 | 4.45 | 4.58 |
| Dewon Brazelton |   | mr | 26 | 1.069 | 67 | .328 | 61 | .670 | 61 | .670 | 23.3 | 11.6 | 10.47 | 9.69 |
| Yhency Brazoban |   | mr | 26 | .841 | 17 | .412 | 11 | .478 | 11 | .478 | 4.1 | 8.0 | 6.69 | 5.74 |
| Craig Breslow* |   | mr | 25 | .715 | 36 | .333 | 23 | .418 | 24 | .436 | 7.1 | 5.3 | 4.81 | 3.78 |
| Eude Brito* |   | mr | 27 | .893 | 63 | .302 | 47 | .540 | 48 | .552 | 15.1 | 7.6 | 6.69 | 6.06 |
| Chris Britton | OTR | mr | 23 | .638 | 159 | .264 | 88 | .398 | 88 | .398 | 21.4 | 3.6 | 3.23 | 2.74 |
| Doug Brocail |   | mr | 39 | .648 | 91 | .286 | 45 | .378 | 45 | .378 | 11.8 | 3.7 | 3.36 | 2.80 |
| Jim Brower |   | mr | 33 | 1.063 | 71 | .423 | 64 | .604 | 69 | .651 | 24.7 | 11.3 | 10.01 | 10.42 |
| Andrew Brown |   | mr | 25 | .541 | 28 | .214 | 15 | .341 | 16 | .364 | 2.9 | 2.6 | 2.34 | 2.87 |
| Jonathan Broxton | CCL | mr | 22 | .647 | 182 | .297 | 131 | .409 | 132 | .412 | 29.6 | 3.4 | 3.14 | 2.97 |
| Brian Bruney |   | mr | 24 | .604 | 48 | .271 | 35 | .389 | 36 | .400 | 7.7 | 3.3 | 3.01 | 3.37 |
| Taylor Buchholz | MUL | sp | 24 | .770 | 344 | .250 | 235 | .491 | 238 | .497 | 61.8 | 4.8 | 4.43 | 3.97 |
| Mark Buehrle* | GEO | sp | 27 | .849 | 688 | .307 | 455 | .519 | 461 | .526 | 133.6 | 6.0 | 5.30 | 5.37 |
| Jason Bulger |   | mr | 27 | .611 | 5 | .200 | 4 | .444 | 4 | .444 | 0.8 | 4.3 | 3.84 | 6.15 |
| Ambiorix Burgos |   | cl | 22 | .890 | 205 | .327 | 185 | .551 | 191 | .568 | 56.4 | 6.9 | 6.23 | 6.51 |
| A.J. Burnett | TON | sp | 29 | .736 | 398 | .312 | 255 | .442 | 263 | .456 | 69.2 | 4.5 | 4.13 | 3.97 |
| Mike Burns |   | mr | 27 | 1.057 | 80 | .475 | 62 | .596 | 64 | .615 | 23.9 | 10.2 | 9.21 | 9.26 |
| Brian Burres* |   | mr | 25 | .526 | 23 | .217 | 10 | .323 | 10 | .323 | 2.3 | 2.6 | 2.35 | 1.91 |
| Dave Bush | OTR | sp | 26 | .720 | 621 | .282 | 374 | .430 | 392 | .451 | 101.8 | 4.4 | 3.93 | 3.47 |
| Paul Byrd |   | sp | 35 | .823 | 647 | .318 | 400 | .497 | 406 | .504 | 124.1 | 6.1 | 5.61 | 5.40 |
| Tim Byrdak* |   | mr | 32 | 1.362 | 30 | .400 | 34 | .810 | 34 | .810 | 13.7 | 16.9 | 15.90 | 15.90 |
| Daniel Cabrera | CRH | sp | 25 | .723 | 385 | .309 | 298 | .450 | 303 | .458 | 75.8 | 4.6 | 4.15 | 4.55 |
| Fernando Cabrera |   | mr | 24 | .801 | 140 | .293 | 133 | .520 | 134 | .523 | 34.8 | 5.2 | 4.65 | 4.72 |
| Matt Cain | LON | sp | 21 | .681 | 528 | .263 | 350 | .428 | 356 | .435 | 89.4 | 4.2 | 3.80 | 3.35 |
| Kiko Calero | LON | mr | 31 | .640 | 146 | .315 | 96 | .398 | 96 | .398 | 23.2 | 3.6 | 3.24 | 3.13 |
| Shawn Camp |   | mr | 30 | .836 | 240 | .350 | 159 | .485 | 166 | .506 | 48.6 | 5.9 | 5.24 | 5.48 |
| Brett Campbell |   | mr | 24 | .931 | 11 | .273 | 11 | .579 | 12 | .632 | 3.3 | 6.8 | 6.08 | 6.01 |
| Jorge Campillo |   | mr | 27 | 1.000 | 10 | .400 | 7 | .636 | 7 | .636 | 2.5 | 9.8 | 8.84 | 5.71 |
| Jose Capellan |   | mr | 25 | .783 | 207 | .261 | 152 | .490 | 155 | .500 | 42.0 | 5.2 | 4.74 | 4.04 |
| Matt Capps | MUL | mr | 22 | .746 | 246 | .280 | 148 | .450 | 151 | .459 | 37.1 | 4.1 | 3.73 | 3.52 |
| Chris Capuano* | BT | sp | 27 | .755 | 677 | .295 | 433 | .463 | 442 | .472 | 116.2 | 4.7 | 4.25 | 3.84 |
| Fausto Carmona | GEO | mr | 22 | .821 | 235 | .336 | 163 | .479 | 170 | .500 | 50.7 | 6.1 | 5.50 | 5.69 |
| Chris Carpenter | CRH | sp | 31 | .643 | 638 | .271 | 344 | .384 | 354 | .395 | 80.6 | 3.2 | 2.95 | 2.75 |
| Giovanni Carrara |   | mr | 38 | .783 | 78 | .282 | 59 | .509 | 60 | .517 | 15.5 | 5.0 | 4.54 | 4.04 |
| Hector Carrasco | LON | mr | 36 | .682 | 303 | .274 | 172 | .412 | 177 | .424 | 41.9 | 3.7 | 3.39 | 3.36 |
| Lance Carter |   | mr | 31 | .934 | 45 | .356 | 33 | .559 | 33 | .559 | 11.4 | 8.8 | 7.94 | 7.91 |
| Santiago Casilla |   | mr | 26 | .775 | 6 | .333 | 5 | .500 | 5 | .500 | 1.2 | 4.7 | 4.21 | 4.61 |
| Scott Cassidy |   | mr | 30 | .816 | 105 | .295 | 95 | .522 | 96 | .527 | 24.4 | 5.1 | 4.63 | 4.44 |
| Fabio Castro* |   | mr | 21 | .514 | 91 | .187 | 39 | .312 | 41 | .328 | 7.0 | 1.9 | 1.80 | 1.76 |
| Gustavo Chacin* |   | sp | 25 | .871 | 274 | .259 | 214 | .557 | 220 | .573 | 61.0 | 6.3 | 5.66 | 5.57 |
| Shawn Chacon |   | sp | 28 | .922 | 359 | .281 | 294 | .570 | 303 | .587 | 93.5 | 7.6 | 6.95 | 6.76 |
| Bruce Chen* |   | mr | 29 | .975 | 320 | .341 | 278 | .614 | 278 | .614 | 91.9 | 8.5 | 7.54 | 7.73 |
| Travis Chick |   | mr | 22 | .977 | 19 | .368 | 19 | .613 | 19 | .613 | 6.0 | 10.8 | 9.70 | 12.69 |
| Jason Childers |   | mr | 31 | .829 | 30 | .367 | 19 | .475 | 19 | .475 | 6.0 | 6.2 | 6.32 | 7.93 |
| Randy Choate* |   | mr | 30 | .766 | 57 | .368 | 31 | .413 | 34 | .453 | 9.9 | 5.3 | 4.99 | 4.87 |
| Vinnie Chulk |   | mr | 27 | .737 | 133 | .301 | 92 | .449 | 95 | .463 | 25.8 | 5.1 | 4.51 | 4.53 |
| Brandon Claussen* |   | sp | 27 | .876 | 246 | .321 | 185 | .527 | 191 | .544 | 59.8 | 7.0 | 6.29 | 6.06 |
| Roger Clemens | ROK | sp | 43 | .596 | 309 | .265 | 162 | .359 | 166 | .368 | 36.7 | 2.9 | 2.62 | 2.33 |
| Matt Clement |   | sp | 31 | .829 | 215 | .321 | 154 | .497 | 160 | .516 | 47.2 | 6.5 | 5.86 | 6.44 |
| Todd Coffey |   | mr | 25 | .755 | 244 | .320 | 157 | .462 | 159 | .468 | 41.4 | 4.7 | 4.30 | 4.29 |
| Jesus Colome |   | mr | 28 | .500 | 1 | .000 | 1 | .500 | 1 | .500 | 0.1 | 3.5 | 3.16 | 7.00 |
| Bartolo Colon |   | sp | 33 | .861 | 195 | .308 | 131 | .522 | 134 | .534 | 39.9 | 6.3 | 5.74 | 5.61 |
| Roman Colon |   | mr | 26 | .868 | 124 | .323 | 91 | .535 | 92 | .541 | 27.0 | 6.4 | 5.65 | 5.56 |
| Clay Condrey |   | mr | 30 | .839 | 94 | .340 | 61 | .500 | 61 | .500 | 17.0 | 5.4 | 4.79 | 5.14 |
| Jose Contreras | GEO | sp | 34 | .710 | 614 | .283 | 357 | .429 | 367 | .441 | 96.6 | 4.4 | 3.99 | 3.72 |
| Aaron Cook | MAD | sp | 27 | .757 | 744 | .302 | 409 | .447 | 416 | .455 | 111.9 | 4.7 | 4.26 | 4.23 |
| Roy Corcoran |   | mr | 26 | 1.057 | 23 | .478 | 21 | .618 | 21 | .618 | 9.0 | 13.5 | 12.83 | 12.96 |
| Tim Corcoran |   | sp | 28 | .810 | 275 | .298 | 199 | .503 | 203 | .513 | 54.6 | 5.5 | 4.89 | 5.04 |
| Chad Cordero |   | cl | 24 | .695 | 200 | .230 | 136 | .443 | 139 | .453 | 33.4 | 4.0 | 3.69 | 3.10 |
| Francisco Cordero | CRH | cl | 31 | .706 | 196 | .316 | 138 | .429 | 141 | .438 | 35.6 | 4.2 | 3.83 | 3.79 |
| Bryan Corey |   | mr | 32 | .667 | 120 | .283 | 66 | .398 | 68 | .410 | 17.5 | 4.1 | 3.63 | 3.13 |
| Lance Cormier |   | mr | 25 | .875 | 241 | .340 | 177 | .532 | 179 | .538 | 52.5 | 6.5 | 5.77 | 6.13 |
| Rheal Cormier* |   | mr | 39 | .762 | 161 | .267 | 93 | .454 | 96 | .468 | 25.3 | 4.8 | 4.26 | 4.13 |
| Manuel Corpas |   | mr | 23 | .783 | 96 | .344 | 64 | .471 | 66 | .485 | 18.1 | 5.1 | 4.52 | 4.39 |
| Kevin Correia | MUL | mr | 25 | .684 | 208 | .284 | 123 | .417 | 126 | .427 | 32.2 | 4.1 | 3.74 | 3.25 |
| David Cortes |   | mr | 32 | .769 | 100 | .320 | 54 | .435 | 55 | .444 | 15.8 | 5.0 | 4.37 | 4.61 |
| Neal Cotts* |   | mr | 26 | .908 | 169 | .308 | 143 | .570 | 146 | .582 | 44.7 | 7.4 | 6.71 | 6.24 |
| Jesse Crain | GEO | mr | 24 | .683 | 239 | .305 | 132 | .406 | 134 | .412 | 35.8 | 4.2 | 3.78 | 3.48 |
| Francisco Cruceta |   | mr | 24 | 1.174 | 24 | .333 | 25 | .735 | 25 | .735 | 9.3 | 13.2 | 11.30 | 11.77 |
| Juan Cruz | TON | mr | 27 | .697 | 260 | .281 | 172 | .416 | 183 | .443 | 45.9 | 4.4 | 3.92 | 3.82 |
| Casey Daigle |   | mr | 25 | .785 | 38 | .342 | 24 | .462 | 24 | .462 | 5.8 | 4.2 | 3.80 | 5.46 |
| Kyle Davies |   | sp | 22 | .980 | 211 | .360 | 188 | .603 | 191 | .612 | 65.0 | 9.1 | 8.32 | 8.33 |
| Doug Davis* |   | sp | 30 | .757 | 619 | .302 | 415 | .459 | 420 | .465 | 115.0 | 5.0 | 4.58 | 4.59 |
| Jason Davis |   | mr | 26 | .742 | 191 | .346 | 102 | .415 | 105 | .427 | 31.3 | 5.1 | 4.59 | 4.20 |
| Zach Day |   | sp | 28 | .842 | 142 | .324 | 94 | .495 | 97 | .511 | 31.1 | 7.0 | 6.30 | 6.68 |
| Jorge De La Rosa* |   | mr | 25 | .825 | 230 | .291 | 191 | .520 | 193 | .526 | 55.2 | 6.2 | 5.66 | 6.05 |
| Mike DeJean |   | mr | 35 | .542 | 6 | .167 | 3 | .375 | 3 | .375 | 0.6 | 3.1 | 2.77 | 3.97 |
| Manny Delcarmen |   | mr | 24 | .785 | 177 | .373 | 110 | .453 | 112 | .461 | 34.9 | 5.9 | 5.30 | 4.90 |
| Chris Demaria |   | mr | 25 | .844 | 37 | .162 | 34 | .540 | 36 | .571 | 9.6 | 6.2 | 5.71 | 5.39 |
| Ryan Dempster | CRH | cl | 29 | .712 | 231 | .312 | 144 | .421 | 147 | .430 | 40.1 | 4.7 | 4.33 | 4.26 |
| Elmer Dessens |   | mr | 35 | .738 | 251 | .311 | 146 | .437 | 147 | .440 | 39.3 | 4.5 | 4.13 | 4.17 |
| Joey Devine |   | mr | 22 | .962 | 15 | .467 | 21 | .583 | 22 | .611 | 6.8 | 9.6 | 8.66 | 11.11 |
| Jose Diaz |   | mr | 22 | 1.086 | 24 | .333 | 25 | .658 | 26 | .684 | 9.2 | 12.4 | 11.13 | 13.68 |
| R.A. Dickey | OTR | sp | 31 | 2.029 | 10 | .200 | 27 | 1.500 | 27 | 1.500 | 13.1 | 39.4 | 31.91 | 32.05 |
| Lenny DiNardo* |   | mr | 26 | .997 | 146 | .377 | 115 | .605 | 116 | .611 | 38.2 | 8.7 | 7.93 | 8.80 |
| Scott Dohmann |   | mr | 28 | .954 | 141 | .355 | 133 | .576 | 137 | .593 | 43.3 | 8.3 | 7.26 | 7.54 |
| Brendan Donnelly | CRH | mr | 34 | .702 | 185 | .270 | 119 | .428 | 123 | .442 | 30.6 | 4.3 | 3.87 | 4.02 |
| Octavio Dotel |   | mr | 32 | 1.130 | 39 | .410 | 41 | .695 | 41 | .695 | 16.0 | 13.9 | 12.93 | 12.97 |
| Scott Downs* | EDG | mr | 30 | .735 | 225 | .284 | 151 | .462 | 153 | .468 | 37.6 | 4.4 | 3.95 | 3.87 |
| Ryan Drese |   | sp | 30 | .823 | 28 | .321 | 20 | .488 | 20 | .488 | 5.7 | 5.9 | 5.35 | 5.70 |
| Eric DuBose* |   | mr | 30 | 1.415 | 16 | .500 | 20 | .870 | 20 | .870 | 7.0 | 13.4 | 12.08 | 18.77 |
| Justin Duchscherer | COP | mr | 28 | .607 | 159 | .302 | 79 | .353 | 80 | .357 | 19.6 | 3.2 | 2.85 | 2.73 |
| Brandon Duckworth |   | sp | 30 | .875 | 160 | .369 | 111 | .514 | 113 | .523 | 35.8 | 7.2 | 6.35 | 6.58 |
| Zach Duke* |   | sp | 23 | .799 | 726 | .328 | 440 | .471 | 447 | .478 | 126.2 | 5.3 | 4.75 | 4.82 |
| Scott Dunn |   | mr | 28 | 1.255 | 33 | .455 | 33 | .733 | 35 | .778 | 14.9 | 17.5 | 15.78 | 15.78 |
| Chad Durbin |   | mr | 28 | .667 | 20 | .250 | 10 | .417 | 10 | .417 | 2.5 | 3.8 | 3.38 | 2.87 |
| Adam Eaton |   | sp | 28 | .848 | 209 | .321 | 150 | .515 | 154 | .529 | 45.1 | 6.3 | 5.62 | 5.98 |
| Joey Eischen* |   | mr | 36 | .900 | 43 | .372 | 46 | .554 | 47 | .566 | 15.3 | 9.2 | 8.47 | 8.82 |
| Scott Elarton |   | sp | 30 | .861 | 368 | .247 | 276 | .551 | 282 | .563 | 78.6 | 6.3 | 5.55 | 5.64 |
| Alan Embree* | LON | mr | 36 | .670 | 149 | .309 | 90 | .407 | 90 | .407 | 24.5 | 4.2 | 3.79 | 3.13 |
| Scott Erickson |   | mr | 38 | .867 | 43 | .256 | 28 | .491 | 31 | .544 | 9.1 | 6.8 | 6.49 | 7.09 |
| Kelvim Escobar | COP | sp | 30 | .707 | 571 | .306 | 335 | .425 | 339 | .430 | 87.0 | 4.1 | 3.72 | 3.67 |
| Shawn Estes* |   | sp | 33 | .551 | 19 | .263 | 8 | .296 | 9 | .333 | 1.8 | 2.5 | 2.42 | 3.35 |
| Seth Etherton |   | sp | 29 | 1.056 | 27 | .259 | 27 | .675 | 27 | .675 | 9.4 | 10.6 | 9.97 | 9.70 |
| Dana Eveland* |   | sp | 22 | .929 | 84 | .417 | 75 | .532 | 80 | .567 | 27.3 | 8.8 | 8.00 | 8.30 |
| Scott Eyre* |   | mr | 34 | .801 | 152 | .329 | 135 | .508 | 135 | .508 | 37.8 | 5.7 | 4.99 | 4.94 |
| Willie Eyre |   | mr | 27 | .870 | 213 | .315 | 142 | .516 | 148 | .538 | 45.4 | 6.9 | 6.20 | 6.07 |
| Brian Falkenborg |   | mr | 28 | .511 | 19 | .263 | 6 | .240 | 7 | .280 | 1.4 | 1.8 | 1.73 | 1.57 |
| Kyle Farnsworth | BON | mr | 30 | .695 | 177 | .305 | 124 | .429 | 125 | .433 | 33.0 | 4.4 | 4.05 | 3.88 |
| Jeff Fassero* |   | mr | 43 | 1.065 | 54 | .352 | 48 | .658 | 48 | .658 | 16.5 | 9.9 | 8.93 | 9.62 |
| Ryan Feierabend* |   | sp | 20 | .721 | 52 | .231 | 34 | .466 | 34 | .466 | 7.6 | 3.8 | 3.64 | 3.91 |
| Scott Feldman | MID | mr | 23 | .697 | 127 | .299 | 69 | .394 | 73 | .417 | 19.4 | 4.3 | 3.80 | 3.94 |
| Pedro Feliciano* | MAD | mr | 29 | .645 | 175 | .297 | 95 | .371 | 98 | .383 | 23.7 | 3.5 | 3.19 | 3.34 |
| Jared Fernandez |   | mr | 34 | 1.120 | 27 | .333 | 23 | .742 | 23 | .742 | 8.6 | 12.2 | 11.02 | 9.19 |
| Nate Field |   | mr | 30 | .921 | 19 | .368 | 25 | .625 | 25 | .625 | 6.8 | 6.8 | 6.15 | 5.45 |
| Randy Flores* |   | mr | 30 | .823 | 128 | .344 | 98 | .500 | 99 | .505 | 28.6 | 6.0 | 5.57 | 5.64 |
| Ron Flores* |   | mr | 26 | .739 | 89 | .281 | 57 | .467 | 57 | .467 | 13.3 | 4.0 | 3.63 | 3.51 |
| Gavin Floyd | TON | sp | 23 | 1.000 | 181 | .309 | 165 | .625 | 168 | .636 | 55.4 | 9.0 | 8.25 | 8.02 |
| Josh Fogg |   | sp | 29 | .862 | 582 | .313 | 406 | .531 | 412 | .539 | 120.5 | 6.3 | 5.67 | 5.36 |
| Bartolome Fortunato |   | mr | 31 | 1.556 | 13 | .385 | 17 | .944 | 18 | 1.000 | 7.9 | 23.7 | 21.30 | 23.41 |
| Casey Fossum* |   | sp | 28 | .786 | 413 | .286 | 284 | .478 | 296 | .498 | 82.9 | 5.6 | 5.16 | 5.25 |
| Keith Foulke |   | mr | 33 | .787 | 151 | .285 | 101 | .493 | 103 | .502 | 28.0 | 5.1 | 4.57 | 4.03 |
| Jeff Francis* | MAD | sp | 25 | .725 | 626 | .270 | 370 | .439 | 383 | .454 | 95.0 | 4.2 | 3.87 | 3.63 |
| Frank Francisco |   | mr | 26 | .813 | 22 | .273 | 17 | .531 | 17 | .531 | 4.4 | 5.1 | 4.82 | 5.17 |
| Ryan Franklin |   | mr | 33 | .867 | 250 | .292 | 186 | .542 | 190 | .554 | 53.1 | 6.2 | 5.57 | 5.41 |
| Wayne Franklin* |   | mr | 32 | .993 | 24 | .250 | 22 | .629 | 22 | .629 | 6.6 | 7.7 | 6.93 | 6.98 |
| Jason Frasor | MID | mr | 28 | .706 | 137 | .285 | 94 | .437 | 96 | .447 | 25.4 | 4.5 | 4.11 | 3.98 |
| Emiliano Fruto |   | mr | 22 | .740 | 101 | .297 | 76 | .461 | 78 | .473 | 20.9 | 5.2 | 4.71 | 5.05 |
| Brian Fuentes* | CCL | cl | 30 | .674 | 161 | .261 | 115 | .420 | 121 | .442 | 27.9 | 3.8 | 3.46 | 3.19 |
| Jeff Fulchino |   | mr | 26 | .500 | 1 | .000 | 1 | .500 | 1 | .500 | 0.1 | 3.5 | 3.16 | 7.00 |
| Aaron Fultz* | MAD | mr | 32 | .814 | 218 | .335 | 157 | .495 | 159 | .502 | 45.7 | 5.7 | 5.19 | 4.64 |
| Kason Gabbard* |   | sp | 24 | .672 | 80 | .300 | 45 | .405 | 45 | .405 | 10.2 | 3.5 | 3.21 | 3.96 |
| Eric Gagne |   | cl | 30 | .250 | 3 | .000 | 1 | .125 | 2 | .250 | 0.1 | 0.6 | 0.53 | 0.94 |
| Mike Gallo* |   | mr | 28 | 1.048 | 63 | .397 | 48 | .585 | 50 | .610 | 18.2 | 10.0 | 9.01 | 10.15 |
| Freddy Garcia | EDG | sp | 30 | .753 | 695 | .282 | 428 | .467 | 435 | .474 | 121.7 | 5.1 | 4.56 | 4.09 |
| Jose Garcia |   | mr | 21 | .685 | 34 | .265 | 21 | .438 | 21 | .438 | 5.4 | 4.4 | 3.98 | 3.64 |
| Jon Garland | COP | sp | 26 | .788 | 715 | .309 | 427 | .474 | 433 | .481 | 119.4 | 5.1 | 4.58 | 4.50 |
| Matt Garza | GEO | sp | 22 | .842 | 165 | .339 | 121 | .522 | 121 | .522 | 37.7 | 6.8 | 6.10 | 5.82 |
| Chad Gaudin |   | mr | 23 | .671 | 194 | .247 | 118 | .428 | 119 | .431 | 29.1 | 4.2 | 3.69 | 3.62 |
| Geoff Geary |   | mr | 29 | .719 | 298 | .326 | 158 | .405 | 164 | .421 | 42.6 | 4.2 | 3.78 | 4.07 |
| Franklyn German |   | mr | 26 | .686 | 35 | .171 | 26 | .456 | 27 | .474 | 6.1 | 4.7 | 4.14 | 4.52 |
| Justin Germano |   | sp | 23 | .832 | 18 | .389 | 15 | .484 | 16 | .516 | 4.1 | 5.3 | 5.01 | 6.26 |
| Tom Glavine* | WIZ | sp | 40 | .746 | 621 | .290 | 380 | .451 | 386 | .458 | 100.0 | 4.5 | 4.09 | 4.01 |
| Jimmy Gobble* |   | mr | 24 | .809 | 248 | .335 | 187 | .505 | 188 | .508 | 52.6 | 5.6 | 5.07 | 4.93 |
| Edgar Gonzalez |   | mr | 23 | .817 | 135 | .281 | 91 | .500 | 94 | .516 | 25.5 | 5.3 | 4.84 | 4.33 |
| Enrique Gonzalez | CCL | sp | 23 | .766 | 344 | .291 | 213 | .461 | 217 | .470 | 59.1 | 5.0 | 4.50 | 4.53 |
| Geremi Gonzalez |   | mr | 31 | .922 | 181 | .337 | 146 | .562 | 148 | .569 | 48.4 | 7.8 | 7.00 | 6.36 |
| Mike Gonzalez* | BT | cl | 28 | .584 | 136 | .301 | 82 | .350 | 84 | .359 | 19.6 | 3.3 | 2.93 | 3.00 |
| Tom Gordon | BT | cl | 38 | .699 | 153 | .288 | 112 | .443 | 113 | .447 | 28.7 | 4.3 | 3.92 | 3.62 |
| Tom Gorzelanny* | LON | sp | 23 | .653 | 189 | .249 | 103 | .386 | 107 | .401 | 25.5 | 3.6 | 3.35 | 3.23 |
| Mike Gosling* |   | mr | 25 | 1.229 | 3 | .000 | 5 | .714 | 6 | .857 | 1.9 | 13.1 | 11.77 | 12.98 |
| John Grabow* |   | mr | 27 | .751 | 197 | .310 | 138 | .455 | 141 | .465 | 37.9 | 4.9 | 4.41 | 4.17 |
| Danny Graves |   | mr | 32 | .879 | 54 | .278 | 36 | .554 | 36 | .554 | 10.7 | 6.6 | 6.18 | 6.19 |
| Sean Green |   | mr | 27 | .749 | 107 | .299 | 61 | .439 | 63 | .453 | 16.8 | 4.8 | 4.26 | 4.47 |
| Kevin Gregg |   | mr | 28 | .753 | 237 | .329 | 155 | .455 | 157 | .460 | 45.4 | 5.3 | 4.69 | 4.51 |
| Zack Greinke | COP | mr | 22 | .757 | 19 | .316 | 13 | .464 | 13 | .464 | 3.7 | 5.5 | 4.69 | 4.93 |
| Jason Grilli |   | mr | 29 | .754 | 203 | .271 | 122 | .452 | 127 | .470 | 34.1 | 5.0 | 4.45 | 4.23 |
| Jason Grimsley |   | mr | 38 | .770 | 96 | .271 | 55 | .466 | 55 | .466 | 14.0 | 4.5 | 4.10 | 4.33 |
| Kevin Gryboski |   | mr | 32 | 1.274 | 25 | .440 | 26 | .743 | 27 | .771 | 12.3 | 18.4 | 17.57 | 18.45 |
| Eddie Guardado* |   | cl | 35 | .910 | 103 | .330 | 95 | .572 | 96 | .578 | 28.4 | 6.8 | 6.21 | 6.26 |
| Matt Guerrier |   | mr | 27 | .760 | 233 | .296 | 137 | .457 | 137 | .457 | 38.1 | 4.9 | 4.43 | 4.59 |
| Jeremy Guthrie |   | mr | 27 | .941 | 60 | .367 | 53 | .570 | 55 | .591 | 17.2 | 8.3 | 7.20 | 7.78 |
| Angel Guzman |   | sp | 24 | .923 | 160 | .369 | 149 | .548 | 155 | .570 | 50.1 | 8.1 | 7.24 | 7.41 |
| Charlie Haeger |   | mr | 22 | .544 | 47 | .255 | 28 | .354 | 28 | .354 | 5.4 | 2.6 | 2.39 | 2.65 |
| John Halama* |   | mr | 34 | .928 | 101 | .317 | 76 | .576 | 76 | .576 | 23.5 | 7.4 | 6.49 | 6.94 |
| Roy Halladay | ROK | sp | 29 | .657 | 686 | .276 | 344 | .393 | 349 | .398 | 83.3 | 3.4 | 3.07 | 2.87 |
| Brad Halsey* |   | mr | 25 | .801 | 316 | .307 | 207 | .480 | 212 | .492 | 60.6 | 5.7 | 5.21 | 5.50 |
| Cole Hamels* | WIZ | sp | 22 | .730 | 343 | .286 | 258 | .462 | 261 | .468 | 67.6 | 4.6 | 4.14 | 3.61 |
| Jason Hammel |   | sp | 23 | .951 | 147 | .367 | 122 | .587 | 123 | .591 | 40.8 | 8.5 | 7.51 | 7.40 |
| Chris Hammond* |   | mr | 40 | .810 | 92 | .337 | 62 | .496 | 62 | .496 | 17.9 | 5.5 | 5.05 | 5.13 |
| Justin Hampson* |   | mr | 26 | 1.102 | 42 | .381 | 42 | .700 | 43 | .717 | 15.6 | 11.7 | 10.55 | 9.41 |
| Tim Hamulack* |   | mr | 29 | .853 | 96 | .302 | 87 | .540 | 89 | .553 | 24.4 | 6.2 | 5.82 | 6.36 |
| Josh Hancock | MUL | mr | 28 | .714 | 240 | .254 | 145 | .449 | 146 | .452 | 34.8 | 3.9 | 3.66 | 3.27 |
| Devern Hansack |   | sp | 28 | .566 | 25 | .160 | 14 | .389 | 14 | .389 | 2.2 | 2.0 | 1.79 | 1.59 |
| Craig Hansen |   | mr | 22 | .846 | 122 | .336 | 86 | .489 | 90 | .511 | 28.1 | 6.6 | 5.99 | 5.93 |
| Aaron Harang | GEO | sp | 28 | .748 | 685 | .312 | 446 | .449 | 454 | .457 | 122.0 | 4.6 | 4.22 | 3.82 |
| Rich Harden | COP | sp | 24 | .618 | 110 | .236 | 77 | .403 | 78 | .408 | 16.4 | 3.2 | 2.84 | 3.07 |
| Dan Haren | LON | sp | 25 | .729 | 668 | .289 | 417 | .448 | 427 | .459 | 109.5 | 4.4 | 3.98 | 3.72 |
| Travis Harper |   | mr | 30 | .942 | 143 | .392 | 110 | .561 | 112 | .571 | 38.3 | 8.4 | 7.38 | 7.16 |
| Jeff Harris |   | mr | 31 | .583 | 11 | .273 | 4 | .333 | 4 | .333 | 0.7 | 1.8 | 1.62 | 1.70 |
| Chad Harville |   | mr | 29 | .765 | 127 | .307 | 86 | .467 | 86 | .467 | 24.7 | 5.4 | 4.87 | 5.15 |
| LaTroy Hawkins |   | mr | 33 | .766 | 215 | .321 | 119 | .456 | 119 | .456 | 35.3 | 5.3 | 4.74 | 4.37 |
| Aaron Heilman | WIZ | mr | 27 | .630 | 247 | .275 | 133 | .374 | 136 | .382 | 32.9 | 3.4 | 3.06 | 2.76 |
| Rick Helling |   | mr | 35 | .719 | 89 | .213 | 69 | .486 | 69 | .486 | 15.8 | 4.1 | 3.65 | 3.13 |
| Ben Hendrickson |   | sp | 25 | .952 | 48 | .438 | 36 | .554 | 36 | .554 | 15.0 | 11.6 | 10.11 | 9.30 |
| Mark Hendrickson* | MUL | sp | 32 | .731 | 537 | .291 | 317 | .441 | 321 | .446 | 86.5 | 4.7 | 4.26 | 4.38 |
| Sean Henn* |   | mr | 25 | .900 | 29 | .310 | 24 | .545 | 25 | .568 | 7.7 | 7.4 | 6.65 | 7.09 |
| Brad Hennessey |   | mr | 26 | .759 | 322 | .248 | 195 | .456 | 205 | .479 | 54.0 | 4.9 | 4.41 | 4.34 |
| Clay Hensley | WIZ | sp | 26 | .703 | 571 | .278 | 338 | .429 | 341 | .433 | 82.9 | 4.0 | 3.59 | 3.64 |
| Matt Herges |   | mr | 36 | .832 | 256 | .348 | 159 | .485 | 162 | .494 | 47.8 | 6.0 | 5.45 | 5.81 |
| Dustin Hermanson |   | mr | 33 | .896 | 18 | .222 | 16 | .593 | 17 | .630 | 4.0 | 5.3 | 4.81 | 4.30 |
| Felix Hernandez | ROK | sp | 20 | .729 | 551 | .312 | 364 | .446 | 370 | .453 | 96.4 | 4.5 | 4.09 | 4.11 |
| Livan Hernandez |   | sp | 31 | .803 | 720 | .301 | 466 | .486 | 470 | .490 | 139.1 | 5.8 | 5.22 | 4.97 |
| Orlando Hernandez | Pal | sp | 36 | .774 | 440 | .302 | 334 | .478 | 346 | .495 | 94.5 | 5.3 | 4.72 | 4.23 |
| Roberto Hernandez |   | mr | 41 | .702 | 199 | .281 | 122 | .428 | 123 | .432 | 31.7 | 4.3 | 4.04 | 3.84 |
| Runelvys Hernandez |   | sp | 28 | .920 | 382 | .322 | 281 | .553 | 287 | .565 | 91.9 | 7.7 | 6.79 | 7.35 |
| Rich Hill* | BT | sp | 26 | .725 | 270 | .248 | 193 | .463 | 195 | .468 | 48.8 | 4.4 | 3.98 | 3.59 |
| Shawn Hill |   | sp | 25 | .788 | 130 | .315 | 74 | .454 | 77 | .472 | 22.5 | 5.6 | 4.98 | 4.70 |
| Jason Hirsh |   | sp | 24 | .849 | 141 | .262 | 111 | .539 | 114 | .553 | 32.8 | 6.5 | 5.95 | 6.11 |
| James Hoey |   | mr | 23 | 1.027 | 35 | .371 | 28 | .571 | 30 | .612 | 11.0 | 10.2 | 9.20 | 8.22 |
| Trevor Hoffman | Pal | cl | 38 | .566 | 178 | .236 | 87 | .351 | 88 | .355 | 18.0 | 2.5 | 2.32 | 2.14 |
| Mike Holtz* |   | mr | 33 | 1.524 | 6 | .500 | 10 | .769 | 11 | .846 | 4.8 | 26.0 | 23.39 | 19.88 |
| J.P. Howell* | MID | sp | 23 | .804 | 133 | .361 | 87 | .465 | 90 | .481 | 26.5 | 5.7 | 5.08 | 5.51 |
| Bob Howry | COP | mr | 32 | .662 | 215 | .288 | 123 | .392 | 126 | .401 | 30.4 | 3.5 | 3.21 | 3.03 |
| Jon Huber |   | mr | 24 | .474 | 49 | .204 | 19 | .288 | 19 | .288 | 3.0 | 1.5 | 1.47 | 1.37 |
| Luke Hudson | MID | sp | 29 | .746 | 327 | .312 | 197 | .448 | 201 | .457 | 51.5 | 4.5 | 4.09 | 4.34 |
| Tim Hudson | GEO | sp | 30 | .775 | 705 | .298 | 453 | .472 | 462 | .482 | 128.4 | 5.3 | 4.77 | 4.54 |
| Travis Hughes |   | mr | 28 | .947 | 39 | .282 | 28 | .519 | 31 | .574 | 9.5 | 7.5 | 6.79 | 7.17 |
| Philip Humber |   | mr | 23 | .143 | 4 | .000 | 1 | .143 | 1 | .143 | 0.1 | 0.5 | 0.45 | 0.27 |
| Jason Isringhausen | Pal | cl | 33 | .740 | 154 | .240 | 122 | .475 | 125 | .486 | 31.4 | 4.9 | 4.37 | 4.63 |
| Edwin Jackson |   | mr | 22 | .826 | 119 | .336 | 87 | .500 | 88 | .506 | 26.6 | 6.5 | 5.94 | 5.86 |
| Zach Jackson* |   | sp | 23 | .867 | 132 | .318 | 92 | .517 | 96 | .539 | 29.4 | 6.8 | 6.21 | 6.26 |
| Chuck James* | Pal | sp | 24 | .739 | 340 | .238 | 233 | .462 | 239 | .474 | 62.2 | 4.7 | 4.23 | 3.84 |
| Casey Janssen | OTR | sp | 24 | .758 | 323 | .282 | 184 | .452 | 191 | .469 | 51.3 | 4.8 | 4.42 | 4.32 |
| Kevin Jarvis |   | mr | 36 | .963 | 106 | .349 | 78 | .578 | 80 | .593 | 27.1 | 8.6 | 7.85 | 6.85 |
| Bobby Jenks | OTR | cl | 25 | .698 | 182 | .335 | 126 | .420 | 128 | .427 | 32.6 | 4.2 | 3.79 | 3.65 |
| Jason Jennings | CCL | sp | 27 | .715 | 655 | .289 | 394 | .437 | 397 | .440 | 101.9 | 4.3 | 3.89 | 3.83 |
| Cesar Jimenez* |   | mr | 21 | 1.300 | 27 | .333 | 33 | .868 | 33 | .868 | 12.6 | 15.5 | 13.97 | 14.01 |
| Ubaldo Jimenez |   | sp | 22 | .563 | 23 | .174 | 11 | .367 | 11 | .367 | 2.3 | 2.7 | 2.42 | 2.48 |
| Jason Johnson |   | sp | 32 | .882 | 419 | .348 | 274 | .520 | 279 | .529 | 90.3 | 7.0 | 6.36 | 6.43 |
| Jim Johnson |   | sp | 23 | 1.557 | 16 | .500 | 18 | .857 | 19 | .905 | 10.6 | 35.7 | 28.55 | 26.81 |
| Josh Johnson | LON | sp | 22 | .689 | 440 | .277 | 280 | .425 | 284 | .431 | 67.6 | 3.9 | 3.49 | 3.48 |
| Randy Johnson* | ROK | sp | 42 | .725 | 590 | .281 | 383 | .445 | 393 | .457 | 100.9 | 4.4 | 3.99 | 3.80 |
| Tyler Johnson* |   | mr | 25 | .783 | 95 | .295 | 79 | .482 | 83 | .506 | 22.2 | 5.6 | 4.96 | 5.16 |
| Greg Jones |   | mr | 29 | .966 | 24 | .292 | 16 | .571 | 16 | .571 | 5.3 | 7.6 | 7.20 | 6.14 |
| Todd Jones | MUL | cl | 38 | .694 | 226 | .292 | 108 | .397 | 111 | .408 | 28.5 | 3.9 | 3.60 | 3.53 |
| Jorge Julio |   | cl | 27 | .705 | 151 | .278 | 133 | .467 | 134 | .470 | 32.4 | 4.4 | 3.98 | 3.72 |
| Steve Karsay |   | mr | 34 | 1.162 | 30 | .300 | 31 | .721 | 32 | .744 | 10.4 | 10.0 | 9.03 | 9.34 |
| Jeff Karstens | BON | sp | 23 | .709 | 145 | .234 | 80 | .447 | 81 | .453 | 21.0 | 4.4 | 3.99 | 3.42 |
| Scott Kazmir* | GEO | sp | 22 | .697 | 378 | .310 | 268 | .439 | 270 | .443 | 69.1 | 4.3 | 3.87 | 3.47 |
| Randy Keisler* |   | mr | 30 | 1.081 | 32 | .344 | 30 | .714 | 30 | .714 | 8.1 | 7.3 | 6.54 | 7.51 |
| Joe Kennedy* |   | mr | 27 | .660 | 104 | .317 | 58 | .392 | 59 | .399 | 13.6 | 3.5 | 3.14 | 3.32 |
| Logan Kensing |   | mr | 23 | .748 | 88 | .273 | 76 | .472 | 79 | .491 | 20.3 | 4.9 | 4.36 | 4.02 |
| Bobby Keppel |   | sp | 24 | .906 | 115 | .339 | 86 | .548 | 87 | .554 | 27.4 | 7.3 | 6.46 | 6.85 |
| Byung-Hyun Kim |   | sp | 27 | .827 | 473 | .340 | 342 | .496 | 350 | .508 | 102.8 | 6.0 | 5.37 | 5.25 |
| Sun-Woo Kim |   | mr | 28 | 1.173 | 51 | .373 | 52 | .712 | 53 | .726 | 21.7 | 14.6 | 12.83 | 12.56 |
| Ray King* |   | mr | 32 | .901 | 148 | .338 | 106 | .533 | 108 | .543 | 31.3 | 6.3 | 5.68 | 6.51 |
| Josh Kinney |   | mr | 27 | .585 | 65 | .215 | 37 | .374 | 38 | .384 | 7.4 | 2.6 | 2.40 | 2.40 |
| Steve Kline* |   | mr | 33 | .756 | 164 | .305 | 102 | .449 | 103 | .454 | 27.2 | 4.7 | 4.27 | 4.35 |
| Dan Kolb |   | mr | 31 | .759 | 162 | .302 | 97 | .455 | 98 | .460 | 26.4 | 4.9 | 4.43 | 4.63 |
| Shane Komine |   | sp | 25 | .941 | 33 | .212 | 28 | .622 | 28 | .622 | 8.2 | 7.9 | 7.42 | 8.41 |
| Mike Koplove |   | mr | 29 | 1.083 | 12 | .417 | 9 | .600 | 9 | .600 | 4.2 | 14.3 | 11.44 | 8.83 |
| John Koronka* |   | sp | 25 | .824 | 424 | .302 | 278 | .502 | 283 | .511 | 84.0 | 6.1 | 5.44 | 5.37 |
| Hong-Chih Kuo* | Pal | mr | 24 | .701 | 150 | .340 | 112 | .434 | 113 | .438 | 27.1 | 4.0 | 3.67 | 3.76 |
| John Lackey | COP | sp | 27 | .671 | 637 | .297 | 369 | .400 | 378 | .410 | 94.1 | 3.9 | 3.50 | 3.31 |
| Juan Lara* |   | mr | 25 | .485 | 16 | .250 | 5 | .263 | 5 | .263 | 0.8 | 1.4 | 1.36 | 1.82 |
| Brandon League | CRH | mr | 23 | .552 | 129 | .240 | 54 | .312 | 57 | .329 | 10.8 | 2.2 | 2.05 | 2.30 |
| Wilfredo Ledezma* |   | mr | 25 | .706 | 195 | .282 | 113 | .428 | 115 | .436 | 30.8 | 4.6 | 4.13 | 3.92 |
| Cliff Lee* | MID | sp | 27 | .776 | 658 | .296 | 418 | .474 | 426 | .483 | 119.1 | 5.3 | 4.81 | 4.69 |
| Justin Lehr |   | mr | 28 | 1.032 | 53 | .415 | 46 | .613 | 47 | .627 | 16.4 | 9.4 | 8.48 | 8.17 |
| Anthony Lerew |   | mr | 23 | 1.145 | 10 | .500 | 9 | .600 | 10 | .667 | 4.2 | 19.0 | 17.11 | 20.57 |
| Jon Lester* | EDG | sp | 22 | .814 | 252 | .333 | 177 | .482 | 182 | .496 | 53.2 | 5.9 | 5.29 | 5.52 |
| Colby Lewis |   | mr | 26 | 1.265 | 11 | .636 | 14 | .778 | 14 | .778 | 6.6 | 19.9 | 17.90 | 17.35 |
| Brad Lidge | Pal | cl | 29 | .736 | 184 | .321 | 153 | .450 | 159 | .468 | 43.2 | 5.0 | 4.66 | 4.25 |
| Cory Lidle |   | sp | 34 | .816 | 516 | .293 | 377 | .506 | 388 | .521 | 105.0 | 5.5 | 4.99 | 4.96 |
| Jon Lieber |   | sp | 36 | .793 | 557 | .303 | 343 | .480 | 349 | .489 | 99.1 | 5.3 | 4.78 | 4.53 |
| Ted Lilly* | OTR | sp | 30 | .764 | 524 | .288 | 385 | .483 | 389 | .488 | 104.2 | 5.1 | 4.65 | 4.57 |
| Jose Lima |   | sp | 33 | .942 | 64 | .344 | 50 | .549 | 52 | .571 | 17.9 | 8.8 | 8.36 | 8.30 |
| Scott Linebrink |   | mr | 29 | .679 | 214 | .285 | 132 | .420 | 133 | .424 | 34.3 | 4.1 | 3.67 | 3.36 |
| Francisco Liriano* | ROK | sp | 22 | .567 | 287 | .279 | 165 | .349 | 166 | .351 | 33.2 | 2.4 | 2.22 | 2.12 |
| Wes Littleton |   | mr | 23 | .538 | 104 | .202 | 45 | .326 | 47 | .341 | 7.5 | 1.8 | 1.67 | 2.10 |
| Bobby Livingston* |   | mr | 23 | 1.198 | 19 | .368 | 22 | .688 | 24 | .750 | 9.5 | 17.0 | 15.34 | 17.47 |
| Esteban Loaiza |   | sp | 34 | .775 | 520 | .312 | 315 | .464 | 320 | .471 | 91.7 | 5.3 | 4.80 | 4.53 |
| Kameron Loe |   | sp | 24 | .845 | 291 | .326 | 183 | .511 | 184 | .514 | 58.0 | 6.6 | 6.00 | 5.79 |
| Adam Loewen* | MID | sp | 22 | .726 | 328 | .314 | 219 | .435 | 227 | .450 | 60.1 | 4.8 | 4.33 | 4.70 |
| Boone Logan* |   | mr | 21 | .862 | 58 | .328 | 47 | .505 | 50 | .538 | 14.8 | 7.1 | 6.92 | 7.56 |
| Kyle Lohse | MID | sp | 27 | .802 | 405 | .333 | 268 | .473 | 274 | .483 | 80.4 | 5.7 | 5.14 | 5.20 |
| Braden Looper | MAD | mr | 31 | .698 | 242 | .302 | 122 | .396 | 124 | .403 | 32.6 | 4.0 | 3.60 | 3.41 |
| Javier Lopez* |   | mr | 28 | .702 | 45 | .267 | 29 | .420 | 31 | .449 | 6.8 | 3.7 | 3.30 | 3.96 |
| Rodrigo Lopez |   | sp | 30 | .853 | 616 | .328 | 446 | .527 | 450 | .531 | 135.5 | 6.4 | 5.81 | 5.68 |
| Derek Lowe | BON | sp | 33 | .670 | 716 | .289 | 359 | .393 | 364 | .399 | 91.6 | 3.7 | 3.40 | 3.42 |
| Mark Lowe |   | mr | 23 | .597 | 43 | .256 | 27 | .360 | 29 | .387 | 5.6 | 2.8 | 2.44 | 2.61 |
| Noah Lowry* |   | sp | 25 | .788 | 522 | .278 | 331 | .480 | 337 | .489 | 92.4 | 5.2 | 4.70 | 4.49 |
| Ruddy Lugo | GEO | mr | 26 | .668 | 269 | .264 | 145 | .399 | 150 | .413 | 35.2 | 3.7 | 3.36 | 3.44 |
| Brandon Lyon | Pal | mr | 26 | .754 | 218 | .280 | 139 | .474 | 139 | .474 | 36.0 | 4.7 | 4.21 | 3.49 |
| Chris Mabeus |   | mr | 27 | 1.583 | 6 | .500 | 12 | 1.000 | 12 | 1.000 | 5.7 | 30.8 | 27.73 | 26.50 |
| Mike MacDougal |   | mr | 29 | .522 | 81 | .247 | 33 | .300 | 34 | .309 | 6.1 | 1.9 | 1.70 | 1.80 |
| Greg Maddux | Pal | sp | 40 | .724 | 688 | .289 | 379 | .440 | 379 | .440 | 100.3 | 4.3 | 3.87 | 3.39 |
| Ryan Madson | CCL | mr | 25 | .903 | 441 | .354 | 333 | .537 | 343 | .553 | 109.4 | 7.3 | 6.60 | 6.50 |
| Ron Mahay* |   | mr | 35 | .747 | 155 | .303 | 117 | .476 | 117 | .476 | 29.0 | 4.5 | 4.13 | 4.28 |
| Paul Maholm* |   | sp | 24 | .824 | 559 | .327 | 386 | .490 | 398 | .505 | 112.6 | 5.8 | 5.18 | 5.58 |
| John Maine | BT | sp | 25 | .686 | 244 | .221 | 163 | .447 | 165 | .452 | 38.7 | 3.9 | 3.48 | 3.22 |
| Gary Majewski |   | mr | 26 | .786 | 235 | .315 | 149 | .472 | 153 | .484 | 42.3 | 5.3 | 4.87 | 4.76 |
| Julio Manon |   | mr | 32 | .926 | 58 | .310 | 60 | .583 | 62 | .602 | 19.2 | 8.2 | 7.78 | 7.94 |
| Shaun Marcum | COP | sp | 24 | .853 | 236 | .309 | 191 | .535 | 195 | .546 | 56.6 | 6.5 | 5.86 | 5.80 |
| Carlos Marmol | WIZ | sp | 23 | .868 | 219 | .260 | 196 | .551 | 201 | .565 | 58.6 | 6.9 | 6.17 | 6.01 |
| Mike Maroth* |   | sp | 28 | .867 | 182 | .291 | 129 | .551 | 130 | .556 | 37.2 | 6.3 | 5.62 | 5.67 |
| Jason Marquis |   | sp | 27 | .873 | 648 | .287 | 464 | .533 | 480 | .552 | 141.2 | 6.6 | 5.89 | 5.79 |
| Sean Marshall* | LON | sp | 23 | .800 | 400 | .280 | 276 | .490 | 283 | .503 | 78.4 | 5.5 | 5.05 | 5.27 |
| Damaso Marte* | WIZ | mr | 31 | .712 | 152 | .303 | 107 | .420 | 111 | .435 | 28.3 | 4.3 | 3.93 | 3.88 |
| Tom Martin* |   | mr | 36 | .760 | 187 | .310 | 123 | .462 | 127 | .477 | 32.8 | 4.8 | 4.40 | 4.16 |
| Carlos Martinez |   | mr | 24 | .619 | 27 | .333 | 16 | .364 | 16 | .364 | 3.9 | 3.4 | 3.04 | 3.42 |
| Pedro Martinez | WIZ | sp | 34 | .672 | 345 | .258 | 227 | .413 | 237 | .431 | 57.6 | 3.9 | 3.52 | 3.18 |
| Nick Masset |   | mr | 24 | .794 | 28 | .321 | 15 | .417 | 17 | .472 | 4.6 | 5.0 | 4.31 | 4.05 |
| Tom Mastny |   | cl | 25 | .722 | 49 | .327 | 30 | .411 | 31 | .425 | 8.8 | 4.9 | 4.35 | 4.53 |
| Juan Mateo |   | sp | 23 | .850 | 143 | .315 | 107 | .510 | 110 | .524 | 32.0 | 6.2 | 5.68 | 5.63 |
| Julio Mateo |   | mr | 28 | .819 | 179 | .313 | 117 | .485 | 120 | .498 | 35.8 | 6.1 | 5.40 | 5.10 |
| Scott Mathieson |   | sp | 22 | .949 | 124 | .323 | 104 | .588 | 105 | .593 | 34.1 | 8.1 | 7.40 | 6.71 |
| Joe Mays |   | sp | 30 | 1.028 | 188 | .356 | 160 | .640 | 160 | .640 | 56.0 | 9.9 | 8.95 | 8.86 |
| Macay McBride* |   | mr | 23 | .699 | 168 | .304 | 107 | .430 | 108 | .434 | 26.5 | 4.2 | 3.79 | 3.85 |
| Brandon McCarthy |   | mr | 22 | .758 | 235 | .255 | 174 | .492 | 174 | .492 | 42.5 | 4.5 | 4.06 | 4.10 |
| Seth McClung |   | mr | 25 | .840 | 345 | .307 | 251 | .513 | 254 | .519 | 78.0 | 6.8 | 6.14 | 6.44 |
| Dustin McGowan |   | mr | 24 | .860 | 92 | .359 | 74 | .517 | 76 | .531 | 24.2 | 7.9 | 7.16 | 7.72 |
| Marty McLeary |   | mr | 31 | .633 | 58 | .276 | 27 | .370 | 27 | .370 | 7.2 | 3.7 | 3.28 | 3.33 |
| Brian Meadows |   | mr | 30 | .871 | 247 | .308 | 168 | .540 | 168 | .540 | 51.2 | 6.5 | 5.96 | 5.58 |
| Gil Meche | CRH | sp | 27 | .768 | 539 | .295 | 389 | .480 | 397 | .490 | 103.7 | 5.0 | 4.50 | 4.56 |
| Brandon Medders |   | mr | 26 | .730 | 234 | .303 | 138 | .437 | 140 | .443 | 37.4 | 4.6 | 4.22 | 4.17 |
| Kent Mercker* |   | mr | 38 | .816 | 89 | .247 | 64 | .520 | 64 | .520 | 16.6 | 5.1 | 4.73 | 4.63 |
| Cla Meredith | WIZ | mr | 23 | .451 | 137 | .197 | 49 | .265 | 51 | .276 | 8.4 | 1.5 | 1.34 | 1.19 |
| Jose Mesa |   | mr | 40 | .786 | 226 | .283 | 150 | .476 | 155 | .492 | 38.9 | 4.8 | 4.36 | 4.98 |
| Randy Messenger |   | mr | 24 | .833 | 197 | .325 | 139 | .505 | 140 | .509 | 41.8 | 6.1 | 5.61 | 5.38 |
| Dan Miceli |   | mr | 35 | .705 | 99 | .212 | 63 | .444 | 64 | .451 | 16.1 | 4.4 | 4.07 | 3.79 |
| Chris Michalak* |   | sp | 35 | .889 | 127 | .283 | 85 | .525 | 88 | .543 | 25.2 | 6.2 | 5.83 | 6.32 |
| Andrew Miller* |   | mr | 21 | .700 | 33 | .242 | 22 | .431 | 24 | .471 | 5.6 | 4.8 | 4.42 | 4.79 |
| Matt Miller |   | mr | 34 | .704 | 40 | .225 | 28 | .431 | 30 | .462 | 6.3 | 3.6 | 3.28 | 3.98 |
| Trever Miller* | CCL | mr | 33 | .671 | 127 | .276 | 85 | .411 | 89 | .430 | 21.2 | 3.8 | 3.40 | 3.11 |
| Wade Miller |   | sp | 29 | .779 | 60 | .250 | 51 | .495 | 52 | .505 | 14.7 | 6.1 | 5.48 | 5.73 |
| Kevin Millwood | CCL | sp | 31 | .735 | 670 | .306 | 404 | .445 | 408 | .450 | 108.1 | 4.5 | 4.07 | 3.92 |
| Eric Milton* |   | sp | 30 | .797 | 496 | .270 | 331 | .500 | 336 | .508 | 93.0 | 5.4 | 4.94 | 4.62 |
| Zach Miner |   | sp | 24 | .762 | 296 | .301 | 187 | .470 | 187 | .470 | 51.0 | 5.0 | 4.45 | 4.44 |
| Patrick Misch* |   | mr | 24 | .800 | 4 | .500 | 2 | .400 | 2 | .400 | 0.8 | 7.2 | 6.48 | 7.48 |
| Sergio Mitre |   | sp | 25 | .806 | 125 | .296 | 89 | .471 | 95 | .503 | 26.4 | 5.7 | 5.21 | 5.87 |
| Brian Moehler |   | sp | 34 | .909 | 436 | .333 | 306 | .550 | 311 | .559 | 95.6 | 7.0 | 6.35 | 6.36 |
| Agustin Montero |   | mr | 28 | .751 | 47 | .255 | 27 | .458 | 27 | .458 | 6.9 | 4.2 | 3.98 | 4.11 |
| Juan Morillo |   | sp | 22 | 1.522 | 13 | .385 | 22 | .917 | 23 | .958 | 10.3 | 23.1 | 20.82 | 20.26 |
| Matt Morris | CCL | sp | 31 | .768 | 687 | .285 | 419 | .464 | 433 | .480 | 119.8 | 5.2 | 4.67 | 4.19 |
| Dustin Moseley |   | sp | 24 | 1.133 | 46 | .413 | 36 | .667 | 36 | .667 | 13.6 | 11.1 | 10.03 | 11.45 |
| Guillermo Mota |   | mr | 32 | .800 | 160 | .275 | 125 | .519 | 125 | .519 | 35.0 | 5.7 | 5.09 | 4.71 |
| Jamie Moyer* |   | sp | 43 | .797 | 697 | .280 | 444 | .497 | 449 | .502 | 119.7 | 5.1 | 4.59 | 4.36 |
| Peter Moylan |   | mr | 27 | .747 | 48 | .354 | 30 | .441 | 30 | .441 | 8.9 | 5.2 | 4.82 | 4.47 |
| Edward Mujica |   | mr | 22 | .773 | 64 | .375 | 33 | .423 | 34 | .436 | 10.6 | 5.3 | 4.66 | 4.50 |
| Mark Mulder* |   | sp | 28 | .950 | 321 | .327 | 247 | .574 | 252 | .586 | 78.8 | 7.5 | 6.84 | 7.04 |
| Terry Mulholland* |   | mr | 43 | 1.462 | 14 | .429 | 14 | .824 | 14 | .824 | 6.7 | 20.2 | 18.17 | 14.72 |
| Scott Munter |   | mr | 26 | .973 | 82 | .354 | 58 | .527 | 60 | .545 | 19.5 | 7.9 | 6.97 | 7.75 |
| Mike Mussina | GEO | sp | 37 | .653 | 570 | .284 | 320 | .398 | 325 | .404 | 76.0 | 3.4 | 3.12 | 3.01 |
| Brett Myers | Pal | sp | 25 | .746 | 549 | .301 | 389 | .467 | 392 | .471 | 100.1 | 4.5 | 4.10 | 4.02 |
| Mike Myers* |   | mr | 37 | .696 | 94 | .277 | 55 | .417 | 58 | .439 | 14.5 | 4.2 | 3.82 | 3.78 |
| Clint Nageotte |   | mr | 25 | 1.571 | 3 | .333 | 7 | 1.000 | 7 | 1.000 | 3.3 | 29.7 | 26.75 | 26.37 |
| Chris Narveson* |   | mr | 24 | .653 | 21 | .238 | 17 | .425 | 18 | .450 | 3.9 | 3.6 | 3.36 | 3.06 |
| Joe Nathan | WIZ | cl | 31 | .454 | 147 | .238 | 74 | .282 | 75 | .286 | 13.4 | 1.7 | 1.59 | 1.18 |
| Jeff Nelson |   | mr | 39 | 1.233 | 7 | .286 | 12 | .800 | 12 | .800 | 3.8 | 12.7 | 11.40 | 13.90 |
| Joe Nelson |   | mr | 31 | .741 | 119 | .269 | 92 | .477 | 93 | .482 | 23.0 | 4.6 | 4.17 | 3.67 |
| Pat Neshek |   | mr | 25 | .531 | 73 | .233 | 48 | .348 | 48 | .348 | 8.9 | 2.2 | 1.95 | 1.68 |
| Fernando Nieve |   | mr | 23 | .773 | 280 | .246 | 204 | .496 | 206 | .501 | 52.3 | 4.9 | 4.40 | 4.24 |
| Dustin Nippert |   | sp | 25 | 1.184 | 30 | .333 | 39 | .765 | 39 | .765 | 13.7 | 11.9 | 11.07 | 12.21 |
| Ricky Nolasco |   | sp | 23 | .804 | 443 | .309 | 293 | .478 | 303 | .494 | 85.0 | 5.4 | 4.92 | 4.89 |
| Roberto Novoa |   | mr | 26 | .817 | 230 | .270 | 171 | .509 | 177 | .527 | 48.9 | 5.7 | 5.21 | 5.16 |
| Leo Nunez |   | mr | 22 | .839 | 42 | .310 | 28 | .483 | 30 | .517 | 7.0 | 4.5 | 4.25 | 5.98 |
| Mike O'Connor* | BT | sp | 25 | .757 | 329 | .246 | 213 | .468 | 220 | .484 | 59.3 | 5.1 | 4.58 | 4.19 |
| Eric O'Flaherty* |   | mr | 21 | .969 | 43 | .372 | 33 | .579 | 33 | .579 | 11.4 | 9.1 | 8.41 | 8.63 |
| Ryan O'Malley* |   | sp | 26 | .583 | 43 | .233 | 19 | .345 | 20 | .364 | 4.4 | 3.1 | 2.78 | 3.08 |
| Tomo Ohka |   | sp | 30 | .754 | 319 | .270 | 190 | .451 | 195 | .463 | 52.7 | 4.9 | 4.40 | 4.32 |
| Will Ohman* | MAD | mr | 28 | .649 | 167 | .269 | 116 | .406 | 121 | .423 | 29.5 | 4.0 | 3.66 | 3.44 |
| Darren Oliver* |   | mr | 35 | .700 | 236 | .242 | 147 | .441 | 150 | .450 | 36.0 | 4.0 | 3.60 | 3.27 |
| Scott Olsen* | TON | sp | 22 | .731 | 490 | .280 | 350 | .460 | 357 | .469 | 88.1 | 4.4 | 3.95 | 3.88 |
| Ramon Ortiz |   | sp | 33 | .849 | 654 | .304 | 441 | .506 | 459 | .527 | 136.7 | 6.4 | 5.81 | 5.71 |
| Russ Ortiz |   | mr | 32 | 1.082 | 198 | .343 | 209 | .690 | 212 | .700 | 70.7 | 10.3 | 9.09 | 9.39 |
| Chad Orvella |   | mr | 25 | 1.076 | 84 | .357 | 84 | .646 | 87 | .669 | 31.1 | 11.2 | 10.37 | 10.81 |
| Franquelis Osoria |   | mr | 24 | .995 | 59 | .390 | 51 | .593 | 52 | .605 | 17.2 | 8.8 | 7.89 | 9.30 |
| Roy Oswalt | BT | sp | 28 | .702 | 668 | .302 | 375 | .419 | 381 | .425 | 94.0 | 3.8 | 3.45 | 3.19 |
| Akinori Otsuka | MAD | cl | 34 | .594 | 171 | .292 | 81 | .349 | 81 | .349 | 17.3 | 2.6 | 2.35 | 2.46 |
| Henry Owens |   | mr | 27 | .707 | 13 | .308 | 8 | .421 | 8 | .421 | 2.2 | 5.0 | 4.54 | 5.79 |
| Vicente Padilla |   | sp | 28 | .757 | 608 | .304 | 394 | .452 | 411 | .471 | 111.6 | 5.0 | 4.52 | 4.41 |
| Jonathan Papelbon | BON | cl | 25 | .465 | 165 | .224 | 74 | .288 | 75 | .292 | 13.7 | 1.8 | 1.63 | 1.22 |
| Chan Ho Park |   | sp | 33 | .791 | 436 | .289 | 289 | .477 | 299 | .493 | 84.8 | 5.5 | 5.03 | 4.62 |
| Chad Paronto | CCL | mr | 30 | .693 | 169 | .284 | 97 | .409 | 100 | .422 | 24.1 | 3.8 | 3.45 | 3.56 |
| John Patterson |   | sp | 28 | .687 | 112 | .286 | 70 | .412 | 73 | .429 | 19.7 | 4.3 | 3.92 | 2.95 |
| David Pauley |   | sp | 23 | 1.043 | 63 | .476 | 48 | .585 | 50 | .610 | 18.7 | 10.7 | 9.47 | 10.41 |
| Jake Peavy | MUL | sp | 25 | .715 | 540 | .304 | 380 | .449 | 386 | .456 | 97.3 | 4.3 | 3.90 | 3.42 |
| Mike Pelfrey |   | sp | 22 | .823 | 70 | .343 | 46 | .465 | 49 | .495 | 14.1 | 6.0 | 5.37 | 6.05 |
| Tony Pena |   | mr | 24 | .879 | 100 | .300 | 76 | .563 | 76 | .563 | 22.3 | 6.5 | 5.89 | 5.12 |
| Hayden Penn |   | sp | 21 | 1.205 | 81 | .370 | 84 | .750 | 86 | .768 | 35.9 | 16.4 | 14.80 | 14.68 |
| Brad Penny | LON | sp | 28 | .764 | 583 | .321 | 372 | .458 | 381 | .469 | 103.2 | 4.9 | 4.42 | 4.32 |
| Joel Peralta |   | mr | 30 | .770 | 218 | .294 | 147 | .484 | 149 | .490 | 37.8 | 4.6 | 4.16 | 3.80 |
| Beltran Perez |   | mr | 24 | .716 | 62 | .210 | 40 | .460 | 40 | .460 | 9.9 | 4.4 | 3.80 | 3.92 |
| Juan Perez* |   | mr | 27 | 1.240 | 10 | .400 | 11 | .647 | 13 | .765 | 4.7 | 12.6 | 11.31 | 11.77 |
| Odalis Perez* |   | sp | 29 | .876 | 440 | .343 | 305 | .532 | 308 | .538 | 98.1 | 7.0 | 6.29 | 5.77 |
| Oliver Perez* |   | sp | 24 | .865 | 333 | .327 | 278 | .526 | 284 | .537 | 87.0 | 7.0 | 6.25 | 6.62 |
| Rafael Perez* |   | mr | 24 | .617 | 33 | .242 | 22 | .393 | 22 | .393 | 5.5 | 3.7 | 3.64 | 3.37 |
| Glen Perkins* |   | mr | 23 | .350 | 14 | .214 | 4 | .200 | 4 | .200 | 0.6 | 1.0 | 0.86 | 0.60 |
| Yusmeiro Petit |   | mr | 21 | 1.125 | 93 | .419 | 91 | .705 | 91 | .705 | 33.0 | 11.3 | 10.15 | 10.07 |
| Andy Pettitte* |   | sp | 34 | .792 | 652 | .324 | 450 | .484 | 452 | .487 | 124.5 | 5.2 | 4.70 | 4.58 |
| Joel Pineiro |   | sp | 27 | .872 | 569 | .327 | 397 | .527 | 407 | .541 | 122.7 | 6.7 | 6.00 | 6.05 |
| Renyel Pinto* |   | mr | 23 | .672 | 68 | .250 | 60 | .444 | 61 | .452 | 12.8 | 3.8 | 3.49 | 4.33 |
| Cliff Politte |   | mr | 32 | 1.071 | 111 | .342 | 102 | .675 | 103 | .682 | 37.1 | 11.1 | 10.03 | 9.39 |
| Sidney Ponson |   | sp | 29 | .875 | 286 | .343 | 201 | .523 | 205 | .534 | 61.3 | 6.5 | 5.85 | 6.25 |
| Mark Prior |   | sp | 25 | .866 | 128 | .289 | 109 | .517 | 117 | .555 | 34.5 | 7.0 | 6.40 | 6.84 |
| Scott Proctor | EDG | mr | 29 | .668 | 290 | .266 | 177 | .415 | 179 | .420 | 43.0 | 3.7 | 3.40 | 3.15 |
| J.J. Putz | MID | cl | 29 | .529 | 180 | .306 | 94 | .310 | 96 | .317 | 20.5 | 2.4 | 2.12 | 1.78 |
| Chad Qualls | LON | mr | 27 | .695 | 256 | .258 | 148 | .416 | 154 | .433 | 33.3 | 3.4 | 3.04 | 3.36 |
| Brad Radke | BON | sp | 33 | .821 | 549 | .315 | 343 | .498 | 344 | .499 | 100.0 | 5.6 | 4.99 | 4.91 |
| Elizardo Ramirez |   | sp | 23 | .831 | 345 | .316 | 232 | .499 | 240 | .516 | 69.6 | 5.9 | 5.42 | 5.13 |
| Horacio Ramirez* | MUL | sp | 26 | .751 | 259 | .305 | 147 | .436 | 151 | .448 | 41.0 | 4.8 | 4.35 | 4.82 |
| Ramon Ramirez | LON | mr | 24 | .677 | 191 | .277 | 121 | .425 | 122 | .428 | 30.0 | 4.0 | 3.59 | 3.09 |
| Santiago Ramirez |   | mr | 27 | 1.069 | 14 | .357 | 12 | .667 | 12 | .667 | 4.7 | 12.6 | 11.36 | 11.76 |
| Darrell Rasner |   | sp | 25 | .701 | 64 | .250 | 36 | .434 | 37 | .446 | 9.2 | 4.1 | 3.65 | 3.07 |
| Jon Rauch |   | mr | 27 | .694 | 246 | .264 | 168 | .439 | 170 | .444 | 42.5 | 4.2 | 3.77 | 3.52 |
| Chris Ray | MID | cl | 24 | .627 | 178 | .197 | 109 | .408 | 110 | .412 | 23.4 | 3.2 | 2.87 | 2.77 |
| Ken Ray |   | mr | 31 | .764 | 202 | .282 | 143 | .478 | 143 | .478 | 37.6 | 5.0 | 4.50 | 4.75 |
| Britt Reames |   | mr | 32 | 1.045 | 24 | .375 | 24 | .649 | 24 | .649 | 8.5 | 10.5 | 9.44 | 9.74 |
| Mark Redman* |   | sp | 32 | .844 | 574 | .319 | 374 | .505 | 382 | .516 | 111.6 | 6.1 | 5.41 | 5.63 |
| Chris Reitsma |   | cl | 28 | 1.048 | 111 | .351 | 89 | .627 | 92 | .648 | 34.4 | 10.9 | 9.95 | 8.85 |
| Mike Remlinger* |   | mr | 40 | .782 | 72 | .347 | 47 | .452 | 49 | .471 | 13.8 | 5.4 | 4.99 | 5.34 |
| Chris Resop |   | mr | 23 | .890 | 73 | .342 | 55 | .545 | 56 | .554 | 16.0 | 6.8 | 6.08 | 6.30 |
| Anthony Reyes |   | sp | 24 | .853 | 240 | .279 | 198 | .535 | 205 | .554 | 56.9 | 6.0 | 5.40 | 5.08 |
| Dennys Reyes* | BON | mr | 29 | .534 | 127 | .252 | 64 | .330 | 64 | .330 | 10.4 | 1.8 | 1.66 | 1.90 |
| John Rheinecker* |   | sp | 27 | .869 | 266 | .368 | 161 | .500 | 164 | .509 | 52.1 | 6.7 | 5.97 | 6.57 |
| Arthur Rhodes* |   | mr | 36 | .756 | 132 | .341 | 99 | .463 | 101 | .472 | 27.5 | 5.4 | 4.88 | 4.63 |
| Juan Rincon | COP | mr | 27 | .669 | 221 | .335 | 119 | .378 | 122 | .387 | 31.6 | 3.9 | 3.44 | 3.53 |
| Ricardo Rincon* |   | mr | 36 | 1.211 | 9 | .556 | 15 | .714 | 16 | .762 | 6.4 | 17.4 | 15.66 | 16.33 |
| Royce Ring* |   | mr | 25 | .542 | 35 | .143 | 18 | .375 | 18 | .375 | 3.3 | 2.3 | 2.10 | 1.60 |
| David Riske | CRH | mr | 29 | .729 | 135 | .252 | 85 | .450 | 88 | .466 | 22.5 | 4.6 | 4.15 | 3.98 |
| Mariano Rivera | ROK | cl | 36 | .552 | 219 | .265 | 90 | .307 | 95 | .324 | 18.6 | 2.2 | 2.01 | 2.03 |
| Saul Rivera |   | mr | 28 | .691 | 196 | .281 | 113 | .408 | 117 | .422 | 31.0 | 4.5 | 4.17 | 4.17 |
| Sendy Rleal |   | mr | 26 | .856 | 151 | .252 | 111 | .547 | 111 | .547 | 29.9 | 5.8 | 5.19 | 5.54 |
| Nate Robertson* |   | sp | 28 | .744 | 640 | .277 | 404 | .459 | 412 | .468 | 102.3 | 4.3 | 3.97 | 4.14 |
| Fernando Rodney | OTR | mr | 29 | .608 | 191 | .236 | 112 | .368 | 120 | .395 | 25.6 | 3.2 | 2.89 | 3.01 |
| Eddy Rodriguez |   | mr | 24 | .958 | 46 | .261 | 45 | .625 | 45 | .625 | 14.1 | 8.3 | 7.64 | 7.72 |
| Felix Rodriguez |   | mr | 33 | .897 | 99 | .273 | 75 | .540 | 79 | .568 | 24.6 | 7.5 | 6.79 | 6.04 |
| Francisco Rodriguez | BON | cl | 24 | .610 | 163 | .282 | 116 | .392 | 117 | .395 | 24.9 | 3.1 | 2.76 | 2.35 |
| Wandy Rodriguez* |   | sp | 27 | .844 | 427 | .321 | 315 | .516 | 321 | .525 | 89.3 | 5.8 | 5.33 | 5.45 |
| Brian Rogers |   | mr | 23 | .996 | 26 | .346 | 23 | .605 | 24 | .632 | 7.6 | 8.2 | 7.13 | 6.65 |
| Kenny Rogers* | EDG | sp | 41 | .715 | 656 | .262 | 371 | .437 | 380 | .448 | 91.8 | 4.0 | 3.64 | 3.76 |
| Davis Romero* |   | mr | 23 | .788 | 53 | .340 | 33 | .465 | 34 | .479 | 10.1 | 5.7 | 5.01 | 4.89 |
| J.C. Romero* |   | mr | 30 | .832 | 163 | .331 | 114 | .504 | 115 | .509 | 34.8 | 6.5 | 5.84 | 5.54 |
| Matt Roney |   | mr | 26 | .820 | 17 | .294 | 8 | .444 | 8 | .444 | 2.7 | 6.0 | 5.43 | 3.63 |
| Francisco Rosario |   | mr | 25 | .819 | 66 | .303 | 56 | .519 | 57 | .528 | 17.8 | 7.1 | 6.27 | 6.12 |
| Josh Rupe |   | mr | 23 | .718 | 100 | .310 | 52 | .413 | 53 | .421 | 14.1 | 4.3 | 3.93 | 4.45 |
| Glendon Rusch* |   | mr | 31 | 1.019 | 197 | .330 | 201 | .646 | 202 | .650 | 65.0 | 8.8 | 7.93 | 8.09 |
| B.J. Ryan* | MID | cl | 30 | .444 | 161 | .242 | 73 | .270 | 73 | .270 | 11.8 | 1.5 | 1.32 | 1.39 |
| Jae Kuk Ryu |   | mr | 23 | 1.176 | 45 | .356 | 56 | .727 | 58 | .753 | 21.5 | 12.6 | 11.60 | 10.72 |
| Kirk Saarloos |   | mr | 27 | .871 | 421 | .309 | 293 | .535 | 296 | .540 | 87.4 | 6.5 | 5.83 | 6.17 |
| C.C. Sabathia* | CRH | sp | 25 | .657 | 562 | .294 | 312 | .389 | 319 | .398 | 77.9 | 3.6 | 3.27 | 3.13 |
| Billy Sadler |   | mr | 24 | 1.165 | 9 | .333 | 15 | .750 | 16 | .800 | 5.5 | 12.4 | 11.16 | 10.38 |
| Takashi Saito | Pal | cl | 36 | .505 | 168 | .268 | 94 | .310 | 96 | .317 | 18.3 | 2.1 | 1.90 | 1.52 |
| Juan Salas |   | mr | 27 | .856 | 36 | .333 | 26 | .542 | 26 | .542 | 8.1 | 6.8 | 6.56 | 5.03 |
| Chris Sampson |   | mr | 28 | .535 | 106 | .208 | 41 | .315 | 42 | .323 | 8.3 | 2.2 | 1.97 | 1.84 |
| Brian Sanches |   | mr | 27 | .920 | 58 | .310 | 60 | .612 | 60 | .612 | 17.7 | 7.6 | 6.73 | 6.18 |
| Anibal Sanchez | MAD | sp | 22 | .635 | 338 | .240 | 185 | .394 | 189 | .403 | 42.8 | 3.4 | 3.03 | 2.96 |
| Duaner Sanchez | MAD | mr | 26 | .632 | 154 | .260 | 85 | .371 | 89 | .389 | 18.7 | 3.0 | 2.73 | 2.85 |
| Jonathan Sanchez* |   | mr | 23 | .722 | 123 | .301 | 80 | .432 | 84 | .454 | 23.7 | 5.3 | 4.81 | 4.54 |
| Ervin Santana | BON | sp | 23 | .707 | 603 | .265 | 367 | .434 | 378 | .447 | 90.6 | 4.0 | 3.60 | 3.51 |
| Johan Santana* | ROK | sp | 27 | .618 | 603 | .269 | 357 | .387 | 361 | .391 | 79.5 | 3.1 | 2.76 | 2.36 |
| Julio Santana |   | mr | 33 | .870 | 28 | .250 | 23 | .535 | 24 | .558 | 6.9 | 7.1 | 6.68 | 6.86 |
| Victor Santos |   | sp | 29 | .889 | 379 | .354 | 280 | .536 | 284 | .544 | 90.0 | 7.1 | 6.32 | 6.20 |
| Dennis Sarfate |   | mr | 25 | .724 | 23 | .391 | 17 | .447 | 17 | .447 | 4.9 | 5.3 | 4.76 | 3.77 |
| Scott Sauerbeck* |   | mr | 34 | .799 | 76 | .250 | 56 | .463 | 63 | .521 | 16.7 | 5.8 | 5.33 | 5.70 |
| Joe Saunders* | MID | sp | 25 | .715 | 215 | .302 | 131 | .434 | 132 | .437 | 32.5 | 4.1 | 3.73 | 4.13 |
| Curt Schilling | CRH | sp | 39 | .761 | 592 | .324 | 393 | .471 | 396 | .475 | 105.1 | 4.7 | 4.17 | 3.83 |
| Jason Schmidt | WIZ | sp | 33 | .689 | 607 | .277 | 381 | .426 | 387 | .433 | 96.0 | 4.1 | 3.65 | 3.43 |
| Scott Schoeneweis* |   | mr | 32 | .702 | 162 | .272 | 95 | .430 | 97 | .439 | 23.7 | 4.1 | 3.71 | 3.79 |
| Chris Schroder |   | mr | 27 | .817 | 61 | .262 | 64 | .504 | 69 | .543 | 18.3 | 5.7 | 5.22 | 5.07 |
| Rudy Seanez |   | mr | 37 | .803 | 154 | .325 | 126 | .506 | 127 | .510 | 37.8 | 6.4 | 5.77 | 5.68 |
| Bobby Seay* |   | mr | 28 | .722 | 46 | .283 | 29 | .408 | 32 | .451 | 8.4 | 4.9 | 4.45 | 4.65 |
| Aaron Sele |   | sp | 36 | .801 | 351 | .311 | 221 | .490 | 223 | .494 | 63.0 | 5.5 | 4.94 | 4.66 |
| Jae Seo |   | sp | 29 | .907 | 528 | .314 | 398 | .563 | 402 | .569 | 121.8 | 7.0 | 6.28 | 6.26 |
| Brian Shackelford* |   | mr | 29 | .887 | 48 | .292 | 44 | .557 | 46 | .582 | 14.1 | 7.8 | 6.99 | 7.10 |
| Josh Sharpless |   | mr | 25 | .546 | 35 | .200 | 19 | .358 | 19 | .358 | 4.6 | 3.4 | 3.08 | 2.86 |
| Ben Sheets | TON | sp | 27 | .699 | 292 | .329 | 182 | .423 | 184 | .428 | 48.6 | 4.1 | 3.72 | 2.84 |
| George Sherrill* | ROK | mr | 29 | .598 | 105 | .286 | 64 | .368 | 64 | .368 | 14.4 | 3.2 | 2.92 | 2.86 |
| James Shields | BON | sp | 24 | .809 | 375 | .328 | 266 | .493 | 271 | .502 | 77.6 | 5.7 | 5.04 | 4.92 |
| Scot Shields | ROK | mr | 30 | .611 | 234 | .265 | 133 | .379 | 134 | .382 | 29.8 | 3.0 | 2.76 | 2.48 |
| Jason Shiell |   | sp | 29 | 1.095 | 51 | .353 | 54 | .675 | 55 | .688 | 19.8 | 11.1 | 10.22 | 9.62 |
| Brian Shouse* | OTR | mr | 37 | .796 | 123 | .293 | 81 | .466 | 87 | .500 | 23.3 | 5.4 | 4.93 | 5.06 |
| Brian Sikorski |   | mr | 31 | .827 | 88 | .318 | 75 | .528 | 76 | .535 | 21.4 | 5.8 | 5.10 | 4.66 |
| Carlos Silva |   | sp | 27 | .892 | 664 | .313 | 440 | .543 | 447 | .551 | 141.3 | 7.0 | 6.34 | 6.23 |
| Allan Simpson |   | mr | 28 | .468 | 5 | .200 | 5 | .357 | 5 | .357 | 0.9 | 2.7 | 2.78 | 3.49 |
| Andrew Sisco* |   | mr | 23 | .829 | 177 | .328 | 140 | .504 | 141 | .507 | 42.7 | 6.6 | 5.93 | 6.14 |
| Doug Slaten* |   | mr | 26 | .417 | 16 | .188 | 5 | .238 | 5 | .238 | 0.7 | 1.1 | 1.03 | 1.11 |
| Brian Slocum |   | mr | 25 | 1.009 | 61 | .393 | 52 | .612 | 53 | .624 | 17.9 | 9.3 | 8.21 | 8.99 |
| Aaron Small |   | mr | 34 | 1.052 | 103 | .320 | 92 | .672 | 93 | .679 | 31.3 | 9.8 | 9.17 | 9.32 |
| Matt Smith* |   | mr | 27 | .354 | 44 | .159 | 19 | .247 | 19 | .247 | 2.0 | 0.9 | 0.79 | 1.13 |
| Mike Smith |   | sp | 28 | 1.286 | 12 | .333 | 14 | .778 | 15 | .833 | 6.0 | 18.1 | 16.25 | 14.84 |
| Travis Smith |   | sp | 33 | .771 | 17 | .294 | 8 | .421 | 8 | .421 | 2.2 | 4.2 | 4.08 | 3.47 |
| John Smoltz | WIZ | sp | 39 | .692 | 662 | .299 | 402 | .419 | 411 | .428 | 102.0 | 3.9 | 3.56 | 3.32 |
| Ian Snell |   | sp | 24 | .811 | 539 | .314 | 408 | .502 | 410 | .504 | 116.8 | 5.7 | 5.09 | 4.86 |
| Kyle Snyder |   | sp | 28 | .924 | 196 | .383 | 163 | .568 | 165 | .575 | 54.1 | 7.9 | 7.26 | 7.21 |
| Alay Soler |   | sp | 26 | .828 | 156 | .276 | 108 | .519 | 109 | .524 | 33.2 | 6.5 | 5.97 | 5.30 |
| Rafael Soriano | GEO | mr | 26 | .613 | 147 | .259 | 93 | .386 | 95 | .394 | 20.9 | 3.1 | 2.82 | 2.64 |
| Jorge Sosa |   | mr | 29 | .891 | 378 | .286 | 297 | .567 | 298 | .569 | 87.5 | 6.6 | 6.01 | 5.88 |
| Jeremy Sowers* | EDG | sp | 23 | .690 | 293 | .256 | 152 | .422 | 154 | .428 | 36.8 | 3.7 | 3.38 | 3.41 |
| Justin Speier | MID | mr | 32 | .701 | 140 | .300 | 99 | .446 | 100 | .450 | 26.4 | 4.6 | 4.17 | 3.55 |
| Russ Springer | WIZ | mr | 37 | .672 | 164 | .220 | 102 | .425 | 106 | .442 | 25.1 | 3.8 | 3.41 | 3.03 |
| Chris Spurling |   | mr | 29 | .865 | 75 | .267 | 53 | .558 | 53 | .558 | 14.6 | 6.1 | 5.55 | 5.73 |
| Jason Standridge |   | mr | 27 | .734 | 51 | .294 | 39 | .453 | 40 | .465 | 10.8 | 5.3 | 4.68 | 5.23 |
| Mike Stanton* |   | mr | 39 | .712 | 211 | .322 | 121 | .417 | 123 | .424 | 32.2 | 4.4 | 3.86 | 3.67 |
| Tim Stauffer | MAD | sp | 24 | .340 | 18 | .167 | 4 | .190 | 4 | .190 | 0.5 | 0.7 | 0.63 | 0.84 |
| Steve Stemle |   | mr | 29 | 1.258 | 32 | .438 | 28 | .778 | 28 | .778 | 12.4 | 17.6 | 16.77 | 15.10 |
| Phil Stockman |   | mr | 26 | .796 | 11 | .273 | 9 | .474 | 9 | .474 | 2.8 | 6.3 | 5.67 | 3.15 |
| Brian Stokes |   | sp | 26 | .837 | 83 | .349 | 54 | .491 | 55 | .500 | 17.6 | 6.7 | 5.94 | 5.75 |
| Huston Street | GEO | cl | 22 | .621 | 204 | .294 | 106 | .366 | 108 | .372 | 27.0 | 3.4 | 3.10 | 2.49 |
| Eric Stults* |   | mr | 26 | .901 | 57 | .228 | 43 | .589 | 43 | .589 | 10.6 | 5.4 | 4.88 | 4.91 |
| Tanyon Sturtze |   | mr | 35 | 1.054 | 40 | .350 | 36 | .643 | 37 | .661 | 13.5 | 11.0 | 10.25 | 10.37 |
| Jeff Suppan |   | sp | 31 | .784 | 635 | .293 | 398 | .476 | 406 | .485 | 110.7 | 5.2 | 4.72 | 4.62 |
| Brian Sweeney | MUL | mr | 32 | .673 | 191 | .246 | 95 | .401 | 96 | .405 | 23.2 | 3.6 | 3.34 | 3.24 |
| Jon Switzer* |   | mr | 26 | .814 | 114 | .289 | 78 | .497 | 79 | .503 | 22.5 | 5.9 | 5.42 | 5.78 |
| Brian Tallet* |   | mr | 28 | .727 | 153 | .261 | 103 | .450 | 106 | .463 | 26.7 | 4.6 | 3.98 | 3.97 |
| Taylor Tankersley* | MAD | mr | 23 | .681 | 101 | .287 | 75 | .421 | 76 | .427 | 18.4 | 4.1 | 3.63 | 3.80 |
| Jack Taschner* |   | mr | 28 | .940 | 73 | .370 | 56 | .554 | 58 | .574 | 20.1 | 8.6 | 8.42 | 8.55 |
| Jordan Tata |   | mr | 24 | .645 | 51 | .255 | 25 | .385 | 25 | .385 | 6.3 | 3.8 | 3.50 | 3.69 |
| Ty Taubenheim |   | sp | 23 | .852 | 114 | .307 | 86 | .515 | 90 | .539 | 28.1 | 7.1 | 6.50 | 6.05 |
| Julian Tavarez |   | mr | 33 | .824 | 315 | .317 | 213 | .494 | 219 | .508 | 58.5 | 5.4 | 4.80 | 5.32 |
| Robinson Tejeda |   | sp | 24 | .797 | 244 | .299 | 158 | .480 | 161 | .489 | 46.0 | 5.6 | 5.05 | 5.41 |
| Brad Thompson |   | mr | 24 | .735 | 184 | .293 | 105 | .429 | 110 | .449 | 27.7 | 4.3 | 3.95 | 4.11 |
| Mike Thompson |   | sp | 25 | .796 | 320 | .281 | 191 | .472 | 198 | .489 | 56.2 | 5.5 | 4.95 | 5.03 |
| John Thomson |   | sp | 32 | .811 | 270 | .304 | 175 | .485 | 177 | .490 | 52.3 | 5.8 | 5.27 | 5.26 |
| Matt Thornton* | CRH | mr | 29 | .649 | 151 | .272 | 91 | .401 | 92 | .405 | 21.9 | 3.6 | 3.28 | 3.12 |
| Mike Timlin | OTR | mr | 40 | .798 | 224 | .317 | 131 | .470 | 133 | .477 | 39.8 | 5.7 | 5.03 | 4.86 |
| Brett Tomko |   | mr | 33 | .789 | 367 | .289 | 239 | .487 | 241 | .491 | 68.6 | 5.4 | 4.94 | 4.37 |
| Salomon Torres | CCL | mr | 34 | .720 | 289 | .318 | 170 | .414 | 176 | .428 | 45.5 | 4.3 | 3.95 | 4.23 |
| Josh Towers |   | sp | 29 | .975 | 223 | .341 | 177 | .600 | 180 | .610 | 62.1 | 8.9 | 8.11 | 8.05 |
| Billy Traber* |   | sp | 26 | .854 | 150 | .320 | 98 | .485 | 106 | .525 | 31.7 | 6.4 | 5.93 | 5.81 |
| Sean Tracey |   | mr | 25 | .651 | 23 | .087 | 15 | .441 | 16 | .471 | 3.1 | 3.3 | 3.10 | 3.65 |
| Steve Trachsel |   | sp | 35 | .830 | 552 | .293 | 377 | .512 | 381 | .518 | 113.2 | 6.3 | 5.57 | 5.55 |
| Derrick Turnbow |   | cl | 28 | .820 | 146 | .329 | 137 | .515 | 141 | .530 | 39.5 | 6.2 | 5.68 | 5.69 |
| Jose Valverde | WIZ | cl | 26 | .738 | 124 | .355 | 101 | .453 | 103 | .462 | 28.9 | 5.2 | 4.74 | 4.42 |
| Jermaine Van Buren |   | mr | 25 | .911 | 41 | .317 | 37 | .569 | 37 | .569 | 11.7 | 8.1 | 7.30 | 7.45 |
| Claudio Vargas |   | sp | 28 | .805 | 537 | .294 | 372 | .498 | 380 | .509 | 106.4 | 5.5 | 5.14 | 4.81 |
| Jason Vargas* |   | mr | 23 | .952 | 145 | .283 | 124 | .582 | 128 | .601 | 41.6 | 8.5 | 7.83 | 7.30 |
| Javier Vazquez | Pal | sp | 29 | .727 | 594 | .308 | 381 | .437 | 396 | .454 | 103.9 | 4.6 | 4.15 | 4.02 |
| Mike Venafro* |   | mr | 32 | .733 | 10 | .300 | 7 | .467 | 7 | .467 | 1.6 | 4.3 | 3.52 | 4.38 |
| Jose Veras |   | mr | 25 | .697 | 30 | .200 | 20 | .465 | 20 | .465 | 4.4 | 3.7 | 3.27 | 3.55 |
| Justin Verlander | COP | sp | 23 | .741 | 565 | .294 | 351 | .452 | 357 | .460 | 91.3 | 4.5 | 3.97 | 4.12 |
| Carlos Villanueva | TON | sp | 22 | .693 | 153 | .229 | 95 | .442 | 99 | .460 | 21.2 | 3.5 | 3.19 | 2.85 |
| Oscar Villarreal |   | mr | 24 | .751 | 297 | .269 | 181 | .456 | 186 | .469 | 49.2 | 4.7 | 4.31 | 4.10 |
| Ron Villone* |   | mr | 36 | .762 | 229 | .288 | 171 | .468 | 175 | .479 | 47.2 | 5.3 | 4.75 | 4.69 |
| Luis Vizcaino | LON | mr | 31 | .708 | 159 | .270 | 123 | .452 | 127 | .467 | 29.2 | 4.0 | 3.62 | 3.34 |
| Ryan Vogelsong |   | mr | 28 | .791 | 126 | .333 | 75 | .421 | 82 | .461 | 26.0 | 6.2 | 5.54 | 5.31 |
| Edinson Volquez |   | sp | 22 | .965 | 124 | .363 | 95 | .579 | 96 | .585 | 34.3 | 9.5 | 8.34 | 9.27 |
| Doug Waechter |   | sp | 25 | .838 | 194 | .314 | 120 | .482 | 125 | .502 | 39.6 | 6.6 | 6.06 | 5.79 |
| Billy Wagner* | BT | cl | 34 | .600 | 171 | .304 | 106 | .357 | 110 | .370 | 24.9 | 3.1 | 2.79 | 2.83 |
| Ryan Wagner |   | mr | 23 | .785 | 101 | .327 | 65 | .461 | 67 | .475 | 20.5 | 6.2 | 5.43 | 5.55 |
| Adam Wainwright | MAD | mr | 24 | .644 | 205 | .283 | 119 | .385 | 123 | .398 | 29.5 | 3.6 | 3.19 | 2.92 |
| Tim Wakefield | OTR | sp | 39 | .735 | 440 | .264 | 276 | .452 | 286 | .469 | 77.9 | 5.0 | 4.51 | 4.22 |
| Jamie Walker* | OTR | mr | 34 | .731 | 143 | .273 | 92 | .469 | 92 | .469 | 22.6 | 4.2 | 3.81 | 3.38 |
| Pete Walker |   | mr | 37 | .842 | 93 | .344 | 73 | .529 | 73 | .529 | 21.9 | 6.5 | 5.92 | 5.93 |
| Tyler Walker |   | cl | 30 | .712 | 79 | .329 | 47 | .423 | 47 | .423 | 13.2 | 4.8 | 4.22 | 4.35 |
| Les Walrond* |   | mr | 29 | .788 | 49 | .347 | 41 | .488 | 41 | .488 | 12.3 | 6.3 | 5.76 | 5.62 |
| Chien-Ming Wang | COP | sp | 26 | .695 | 758 | .292 | 367 | .408 | 369 | .410 | 90.5 | 3.7 | 3.36 | 3.62 |
| John Wasdin |   | sp | 33 | .822 | 102 | .265 | 71 | .504 | 75 | .532 | 21.6 | 6.3 | 5.83 | 5.93 |
| Jarrod Washburn* |   | sp | 31 | .766 | 619 | .279 | 382 | .472 | 389 | .481 | 104.7 | 5.0 | 4.53 | 4.33 |
| David Weathers | TON | mr | 36 | .718 | 216 | .227 | 143 | .455 | 145 | .462 | 35.7 | 4.3 | 3.92 | 3.79 |
| Jeff Weaver |   | sp | 29 | .877 | 572 | .313 | 414 | .538 | 424 | .551 | 126.8 | 6.6 | 5.97 | 5.90 |
| Jered Weaver | OTR | sp | 23 | .626 | 334 | .237 | 195 | .398 | 198 | .404 | 44.5 | 3.3 | 2.93 | 2.57 |
| Brandon Webb | TON | sp | 27 | .650 | 701 | .287 | 367 | .386 | 373 | .393 | 86.5 | 3.3 | 2.98 | 2.81 |
| Todd Wellemeyer |   | mr | 27 | .736 | 231 | .268 | 157 | .455 | 161 | .467 | 40.8 | 4.7 | 4.22 | 4.28 |
| David Wells* | EDG | sp | 43 | .817 | 263 | .327 | 160 | .494 | 160 | .494 | 47.8 | 5.7 | 5.14 | 5.14 |
| Kip Wells |   | sp | 29 | .902 | 160 | .363 | 109 | .524 | 113 | .543 | 34.7 | 7.1 | 6.35 | 6.90 |
| Jake Westbrook | MID | sp | 28 | .743 | 721 | .322 | 391 | .433 | 395 | .437 | 107.8 | 4.6 | 4.13 | 4.39 |
| Dan Wheeler | Pal | mr | 28 | .649 | 196 | .270 | 119 | .403 | 121 | .410 | 28.3 | 3.6 | 3.21 | 2.57 |
| Rick White |   | mr | 37 | .794 | 205 | .312 | 129 | .467 | 132 | .478 | 36.1 | 5.0 | 4.52 | 4.82 |
| Bob Wickman | COP | cl | 37 | .626 | 175 | .291 | 83 | .356 | 84 | .361 | 21.9 | 3.5 | 3.29 | 2.89 |
| Dave Williams* |   | sp | 27 | .916 | 248 | .319 | 173 | .541 | 179 | .559 | 56.8 | 7.3 | 6.67 | 6.82 |
| Jerome Williams |   | mr | 24 | 1.008 | 42 | .310 | 37 | .607 | 38 | .623 | 12.2 | 8.9 | 7.99 | 8.42 |
| Todd Williams |   | mr | 35 | .863 | 207 | .329 | 133 | .512 | 135 | .519 | 38.9 | 5.9 | 5.53 | 6.19 |
| Woody Williams | MUL | sp | 39 | .751 | 489 | .268 | 284 | .455 | 291 | .466 | 78.9 | 4.8 | 4.40 | 4.12 |
| Scott Williamson |   | mr | 30 | .794 | 107 | .346 | 87 | .494 | 88 | .500 | 25.6 | 5.8 | 5.27 | 5.09 |
| Dontrelle Willis* | MAD | sp | 24 | .745 | 692 | .308 | 422 | .433 | 441 | .452 | 115.4 | 4.6 | 4.19 | 4.53 |
| Brian Wilson |   | mr | 24 | .763 | 95 | .326 | 64 | .454 | 65 | .461 | 18.4 | 5.5 | 4.96 | 5.11 |
| C.J. Wilson* | ROK | mr | 25 | .722 | 118 | .271 | 84 | .440 | 89 | .466 | 21.2 | 4.2 | 3.87 | 4.25 |
| Kris Wilson |   | mr | 29 | 1.165 | 28 | .357 | 32 | .762 | 32 | .762 | 11.8 | 12.7 | 11.43 | 12.24 |
| Jason Windsor |   | sp | 23 | .966 | 52 | .365 | 36 | .554 | 36 | .554 | 12.5 | 8.1 | 7.43 | 7.64 |
| Joe Winkelsas |   | mr | 32 | .877 | 24 | .333 | 19 | .543 | 19 | .543 | 5.4 | 6.6 | 6.26 | 8.18 |
| Matt Wise |   | mr | 30 | .758 | 139 | .281 | 86 | .457 | 88 | .468 | 22.1 | 4.4 | 4.03 | 4.23 |
| Jay Witasick |   | mr | 33 | .862 | 63 | .349 | 60 | .541 | 61 | .550 | 17.7 | 7.1 | 6.33 | 7.25 |
| Randy Wolf* |   | sp | 29 | .912 | 169 | .296 | 151 | .579 | 153 | .586 | 47.1 | 7.6 | 6.73 | 6.63 |
| Kerry Wood | MUL | sp | 29 | .846 | 59 | .237 | 47 | .547 | 48 | .558 | 13.1 | 5.9 | 5.41 | 5.17 |
| Mike Wood |   | mr | 26 | .868 | 238 | .319 | 157 | .511 | 164 | .534 | 50.6 | 6.9 | 6.34 | 6.57 |
| Jake Woods* |   | mr | 24 | .808 | 340 | .303 | 238 | .503 | 240 | .507 | 67.5 | 5.8 | 5.21 | 5.16 |
| Tim Worrell |   | cl | 38 | 1.012 | 70 | .271 | 66 | .667 | 67 | .677 | 21.8 | 9.2 | 8.68 | 8.73 |
| Jamey Wright |   | sp | 31 | .784 | 507 | .298 | 316 | .467 | 326 | .482 | 87.1 | 5.0 | 4.52 | 4.89 |
| Jaret Wright |   | sp | 30 | .770 | 467 | .315 | 287 | .459 | 294 | .470 | 81.2 | 5.2 | 4.69 | 4.78 |
| Michael Wuertz | BT | mr | 27 | .677 | 111 | .270 | 74 | .423 | 75 | .429 | 19.1 | 4.2 | 3.80 | 3.37 |
| Esteban Yan |   | mr | 31 | .800 | 108 | .222 | 83 | .516 | 84 | .522 | 19.9 | 4.6 | 4.31 | 4.58 |
| Tyler Yates | TON | mr | 28 | .747 | 134 | .269 | 106 | .488 | 106 | .488 | 25.6 | 4.6 | 4.15 | 3.95 |
| Shane Youman* |   | sp | 26 | .571 | 72 | .194 | 31 | .352 | 31 | .352 | 6.6 | 2.7 | 2.46 | 2.37 |
| Chris Young | COP | sp | 27 | .670 | 468 | .226 | 317 | .431 | 323 | .439 | 78.7 | 3.9 | 3.55 | 3.12 |
| Carlos Zambrano | CCL | sp | 25 | .667 | 563 | .252 | 388 | .423 | 397 | .433 | 90.5 | 3.7 | 3.42 | 3.34 |
| Victor Zambrano |   | sp | 30 | .871 | 66 | .303 | 54 | .557 | 54 | .557 | 16.4 | 7.0 | 6.24 | 6.69 |
| Barry Zito* | EDG | sp | 28 | .759 | 655 | .281 | 439 | .465 | 452 | .478 | 112.2 | 4.6 | 4.11 | 4.47 |
| Joel Zumaya | ROK | mr | 21 | .557 | 203 | .246 | 123 | .351 | 125 | .357 | 27.2 | 2.9 | 2.64 | 2.55 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% |
| David Aardsma | BT | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 |
| Winston Abreu |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Jeremy Accardo |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 |
| Mike Adams | MUL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jon Adkins |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 |
| Jeremy Affeldt* | CRH | mr | 27 | 9 | 0 | .000 | 0 | 1 | .111 | 37 | 4.1 | 26 | 10 | .385 |
| Matt Albers |   | sp | 23 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 3 | 1 | .333 |
| Antonio Alfonseca |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Abe Alvarez* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Steve Andrade |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Greg Aquino |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Tony Armas |   | sp | 28 | 30 | 0 | .000 | 0 | 13 | .433 | 149 | 5.0 | 21 | 6 | .286 |
| Bronson Arroyo | BT | sp | 29 | 35 | 3 | .086 | 1 | 23 | .657 | 158 | 4.5 | 3 | 2 | .667 |
| Miguel Asencio |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 2 | 0 | .000 |
| Ezequiel Astacio |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 |
| Pedro Astacio |   | sp | 36 | 17 | 1 | .059 | 1 | 5 | .294 | 96 | 5.6 | 19 | 6 | .316 |
| Brandon Backe |   | sp | 28 | 8 | 0 | .000 | 0 | 4 | .500 | 33 | 4.1 | 3 | 0 | .000 |
| Cha Seung Baek |   | sp | 26 | 6 | 0 | .000 | 0 | 3 | .500 | 29 | 4.8 | 3 | 1 | .333 |
| Danys Baez |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 |
| Jeff Bajenaru |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Scott Baker |   | sp | 24 | 16 | 0 | .000 | 0 | 4 | .250 | 69 | 4.3 | 6 | 3 | .500 |
| Brian Bannister |   | sp | 25 | 6 | 0 | .000 | 0 | 2 | .333 | 34 | 5.7 | 0 | 0 | .000 |
| Kevin Barry |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 9 | 2 | .222 |
| Phil Barzilla* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Miguel Batista |   | sp | 35 | 33 | 3 | .091 | 1 | 17 | .515 | 181 | 5.5 | 14 | 2 | .143 |
| Rick Bauer | EDG | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 13 | 3 | .231 |
| Denny Bautista |   | sp | 23 | 8 | 0 | .000 | 0 | 2 | .250 | 42 | 5.3 | 7 | 3 | .429 |
| Jonah Bayliss |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| T.J. Beam |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 |
| Colter Bean |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Josh Beckett | Pal | sp | 26 | 33 | 0 | .000 | 0 | 19 | .576 | 167 | 5.1 | 12 | 5 | .417 |
| Erik Bedard* | GEO | sp | 27 | 33 | 0 | .000 | 0 | 20 | .606 | 162 | 4.9 | 9 | 2 | .222 |
| Joe Beimel* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 |
| Matt Belisle |   | mr | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 10 | 2 | .200 |
| Heath Bell | MUL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Armando Benitez |   | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Joaquin Benoit | OTR | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 12 | .600 |
| Kris Benson |   | sp | 31 | 30 | 3 | .100 | 0 | 18 | .600 | 142 | 4.7 | 12 | 2 | .167 |
| Jason Bergmann |   | mr | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 23 | 3.8 | 12 | 4 | .333 |
| Adam Bernero |   | sp | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 14 | 4.7 | 1 | 0 | .000 |
| Rafael Betancourt | GEO | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Chad Billingsley | TON | sp | 21 | 16 | 0 | .000 | 0 | 6 | .375 | 76 | 4.8 | 9 | 4 | .444 |
| Kurt Birkins* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 |
| Joe Blanton | BON | sp | 25 | 31 | 1 | .032 | 1 | 16 | .516 | 148 | 4.8 | 17 | 8 | .471 |
| Jeremy Bonderman | OTR | sp | 23 | 34 | 0 | .000 | 0 | 19 | .559 | 165 | 4.9 | 17 | 4 | .235 |
| Boof Bonser | BON | sp | 24 | 18 | 0 | .000 | 0 | 7 | .389 | 86 | 4.8 | 11 | 3 | .273 |
| Chris Booker |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Chris Bootcheck |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Dave Borkowski |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 |
| Joe Borowski |   | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Micah Bowie* |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Blaine Boyer |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Chad Bradford | EDG | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 |
| Ryan Braun |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Bill Bray* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 |
| Dewon Brazelton |   | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 5 | 4 | .800 |
| Yhency Brazoban |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Craig Breslow* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Eude Brito* |   | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 4 | 2.0 | 1 | 0 | .000 |
| Chris Britton | OTR | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Doug Brocail |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 |
| Jim Brower |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 |
| Andrew Brown |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Jonathan Broxton | CCL | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Brian Bruney |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Taylor Buchholz | MUL | sp | 24 | 19 | 1 | .053 | 1 | 8 | .421 | 70 | 3.7 | 14 | 8 | .571 |
| Mark Buehrle* | GEO | sp | 27 | 32 | 1 | .031 | 0 | 16 | .500 | 151 | 4.7 | 16 | 3 | .188 |
| Jason Bulger |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Ambiorix Burgos |   | cl | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 21 | 5 | .238 |
| A.J. Burnett | TON | sp | 29 | 21 | 2 | .095 | 1 | 12 | .571 | 106 | 5.0 | 7 | 3 | .429 |
| Mike Burns |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Brian Burres* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Dave Bush | OTR | sp | 26 | 32 | 3 | .094 | 2 | 18 | .563 | 157 | 4.9 | 7 | 1 | .143 |
| Paul Byrd |   | sp | 35 | 31 | 1 | .032 | 0 | 15 | .484 | 195 | 6.3 | 15 | 3 | .200 |
| Tim Byrdak* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Daniel Cabrera | CRH | sp | 25 | 26 | 2 | .077 | 1 | 10 | .385 | 142 | 5.5 | 10 | 6 | .600 |
| Fernando Cabrera |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 |
| Matt Cain | LON | sp | 21 | 31 | 1 | .032 | 1 | 14 | .452 | 140 | 4.5 | 18 | 9 | .500 |
| Kiko Calero | LON | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 9 | .273 |
| Shawn Camp |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 12 | .364 |
| Brett Campbell |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jorge Campillo |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Jose Capellan |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 |
| Matt Capps | MUL | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 |
| Chris Capuano* | BT | sp | 27 | 34 | 3 | .088 | 2 | 25 | .735 | 132 | 3.9 | 7 | 0 | .000 |
| Fausto Carmona | GEO | mr | 22 | 7 | 0 | .000 | 0 | 3 | .429 | 33 | 4.7 | 11 | 6 | .545 |
| Chris Carpenter | CRH | sp | 31 | 32 | 5 | .156 | 3 | 19 | .594 | 151 | 4.7 | 6 | 2 | .333 |
| Giovanni Carrara |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 |
| Hector Carrasco | LON | mr | 36 | 3 | 0 | .000 | 0 | 1 | .333 | 8 | 2.7 | 18 | 6 | .333 |
| Lance Carter |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Santiago Casilla |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Scott Cassidy |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Fabio Castro* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Gustavo Chacin* |   | sp | 25 | 17 | 0 | .000 | 0 | 6 | .353 | 107 | 6.3 | 9 | 2 | .222 |
| Shawn Chacon |   | sp | 28 | 20 | 0 | .000 | 0 | 5 | .250 | 92 | 4.6 | 28 | 9 | .321 |
| Bruce Chen* |   | mr | 29 | 12 | 0 | .000 | 0 | 1 | .083 | 43 | 3.6 | 18 | 11 | .611 |
| Travis Chick |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Jason Childers |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Randy Choate* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 |
| Vinnie Chulk |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Brandon Claussen* |   | sp | 27 | 14 | 0 | .000 | 0 | 4 | .286 | 51 | 3.6 | 9 | 5 | .556 |
| Roger Clemens | ROK | sp | 43 | 19 | 0 | .000 | 0 | 12 | .632 | 75 | 3.9 | 4 | 2 | .500 |
| Matt Clement |   | sp | 31 | 12 | 0 | .000 | 0 | 4 | .333 | 68 | 5.7 | 12 | 5 | .417 |
| Todd Coffey |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 |
| Jesus Colome |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Bartolo Colon |   | sp | 33 | 10 | 1 | .100 | 1 | 5 | .500 | 47 | 4.7 | 8 | 2 | .250 |
| Roman Colon |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 10 | 4 | .400 |
| Clay Condrey |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Jose Contreras | GEO | sp | 34 | 30 | 1 | .033 | 1 | 16 | .533 | 158 | 5.3 | 15 | 8 | .533 |
| Aaron Cook | MAD | sp | 27 | 32 | 0 | .000 | 0 | 18 | .563 | 127 | 4.0 | 24 | 11 | .458 |
| Roy Corcoran |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Tim Corcoran |   | sp | 28 | 16 | 0 | .000 | 0 | 7 | .438 | 70 | 4.4 | 13 | 3 | .231 |
| Chad Cordero |   | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Francisco Cordero | CRH | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Bryan Corey |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 |
| Lance Cormier |   | mr | 25 | 9 | 0 | .000 | 0 | 4 | .444 | 28 | 3.1 | 16 | 8 | .500 |
| Rheal Cormier* |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 2 | .091 |
| Manuel Corpas |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 |
| Kevin Correia | MUL | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 |
| David Cortes |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 |
| Neal Cotts* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 10 | .233 |
| Jesse Crain | GEO | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 3 | .115 |
| Francisco Cruceta |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 1 | 0 | .000 |
| Juan Cruz | TON | mr | 27 | 15 | 0 | .000 | 0 | 5 | .333 | 68 | 4.5 | 5 | 2 | .400 |
| Casey Daigle |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Kyle Davies |   | sp | 22 | 14 | 1 | .071 | 0 | 2 | .143 | 86 | 6.1 | 12 | 6 | .500 |
| Doug Davis* |   | sp | 30 | 34 | 1 | .029 | 1 | 16 | .471 | 184 | 5.4 | 20 | 4 | .200 |
| Jason Davis |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 |
| Zach Day |   | sp | 28 | 8 | 0 | .000 | 0 | 3 | .375 | 39 | 4.9 | 5 | 2 | .400 |
| Jorge De La Rosa* |   | mr | 25 | 13 | 0 | .000 | 0 | 1 | .077 | 56 | 4.3 | 33 | 20 | .606 |
| Mike DeJean |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Manny Delcarmen |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 10 | .357 |
| Chris Demaria |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Ryan Dempster | CRH | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 |
| Elmer Dessens |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 |
| Joey Devine |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Jose Diaz |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| R.A. Dickey | OTR | sp | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 0 | 0 | .000 |
| Lenny DiNardo* |   | mr | 26 | 6 | 0 | .000 | 0 | 0 | .000 | 38 | 6.3 | 11 | 6 | .545 |
| Scott Dohmann |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 10 | .400 |
| Brendan Donnelly | CRH | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 |
| Octavio Dotel |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Scott Downs* | EDG | mr | 30 | 5 | 0 | .000 | 0 | 0 | .000 | 33 | 6.6 | 27 | 10 | .370 |
| Ryan Drese |   | sp | 30 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 2 | 0 | .000 |
| Eric DuBose* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Justin Duchscherer | COP | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 |
| Brandon Duckworth |   | sp | 30 | 8 | 0 | .000 | 0 | 2 | .250 | 32 | 4.0 | 11 | 3 | .273 |
| Zach Duke* |   | sp | 23 | 34 | 2 | .059 | 1 | 18 | .529 | 142 | 4.2 | 14 | 6 | .429 |
| Scott Dunn |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 |
| Chad Durbin |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Adam Eaton |   | sp | 28 | 13 | 0 | .000 | 0 | 4 | .308 | 82 | 6.3 | 11 | 1 | .091 |
| Joey Eischen* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 |
| Scott Elarton |   | sp | 30 | 20 | 0 | .000 | 0 | 6 | .300 | 87 | 4.3 | 22 | 10 | .455 |
| Alan Embree* | LON | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 3 | .100 |
| Scott Erickson |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 |
| Kelvim Escobar | COP | sp | 30 | 30 | 1 | .033 | 0 | 20 | .667 | 112 | 3.7 | 11 | 7 | .636 |
| Shawn Estes* |   | sp | 33 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 0 | 0 | .000 |
| Seth Etherton |   | sp | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 1 | 0 | .000 |
| Dana Eveland* |   | sp | 22 | 5 | 0 | .000 | 0 | 0 | .000 | 22 | 4.4 | 10 | 3 | .300 |
| Scott Eyre* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 2 | .071 |
| Willie Eyre |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 |
| Brian Falkenborg |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Kyle Farnsworth | BON | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 |
| Jeff Fassero* |   | mr | 43 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 5 | 1 | .200 |
| Ryan Feierabend* |   | sp | 20 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 0 | 0 | .000 |
| Scott Feldman | MID | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 |
| Pedro Feliciano* | MAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 6 | .176 |
| Jared Fernandez |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Nate Field |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 |
| Randy Flores* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 13 | .317 |
| Ron Flores* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Gavin Floyd | TON | sp | 23 | 11 | 1 | .091 | 1 | 3 | .273 | 61 | 5.5 | 14 | 7 | .500 |
| Josh Fogg |   | sp | 29 | 31 | 1 | .032 | 1 | 14 | .452 | 164 | 5.3 | 26 | 7 | .269 |
| Bartolome Fortunato |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 |
| Casey Fossum* |   | sp | 28 | 25 | 0 | .000 | 0 | 10 | .400 | 148 | 5.9 | 18 | 10 | .556 |
| Keith Foulke |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Jeff Francis* | MAD | sp | 25 | 32 | 1 | .031 | 1 | 15 | .469 | 175 | 5.5 | 26 | 11 | .423 |
| Frank Francisco |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Ryan Franklin |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Wayne Franklin* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Jason Frasor | MID | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 9 | .474 |
| Emiliano Fruto |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 |
| Brian Fuentes* | CCL | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Jeff Fulchino |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Aaron Fultz* | MAD | mr | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 14 | 1 | .071 |
| Kason Gabbard* |   | sp | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 9 | 2.3 | 10 | 5 | .500 |
| Eric Gagne |   | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mike Gallo* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 |
| Freddy Garcia | EDG | sp | 30 | 33 | 1 | .030 | 0 | 18 | .545 | 188 | 5.7 | 15 | 9 | .600 |
| Jose Garcia |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Jon Garland | COP | sp | 26 | 32 | 1 | .031 | 1 | 17 | .531 | 180 | 5.6 | 24 | 11 | .458 |
| Matt Garza | GEO | sp | 22 | 9 | 0 | .000 | 0 | 2 | .222 | 33 | 3.7 | 10 | 1 | .100 |
| Chad Gaudin |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 10 | .435 |
| Geoff Geary |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 |
| Franklyn German |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Justin Germano |   | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 2 | 0 | .000 |
| Tom Glavine* | WIZ | sp | 40 | 32 | 0 | .000 | 0 | 22 | .688 | 172 | 5.4 | 21 | 10 | .476 |
| Jimmy Gobble* |   | mr | 24 | 6 | 0 | .000 | 0 | 0 | .000 | 26 | 4.3 | 29 | 10 | .345 |
| Edgar Gonzalez |   | mr | 23 | 5 | 0 | .000 | 0 | 4 | .800 | 19 | 3.8 | 6 | 1 | .167 |
| Enrique Gonzalez | CCL | sp | 23 | 18 | 0 | .000 | 0 | 7 | .389 | 81 | 4.5 | 3 | 1 | .333 |
| Geremi Gonzalez |   | mr | 31 | 4 | 0 | .000 | 0 | 1 | .250 | 24 | 6.0 | 8 | 2 | .250 |
| Mike Gonzalez* | BT | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Tom Gordon | BT | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Tom Gorzelanny* | LON | sp | 23 | 11 | 0 | .000 | 0 | 6 | .545 | 42 | 3.8 | 3 | 2 | .667 |
| Mike Gosling* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| John Grabow* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 10 | .227 |
| Danny Graves |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Sean Green |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 |
| Kevin Gregg |   | mr | 28 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 11 | 4 | .364 |
| Zack Greinke | COP | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jason Grilli |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 6 | .222 |
| Jason Grimsley |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Kevin Gryboski |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Eddie Guardado* |   | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 |
| Matt Guerrier |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 8 | 4 | .500 |
| Jeremy Guthrie |   | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 3 | 1 | .333 |
| Angel Guzman |   | sp | 24 | 10 | 0 | .000 | 0 | 1 | .100 | 32 | 3.2 | 12 | 9 | .750 |
| Charlie Haeger |   | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 3 | 0 | .000 |
| John Halama* |   | mr | 34 | 1 | 0 | .000 | 0 | 0 | .000 | 14 | 14.0 | 6 | 2 | .333 |
| Roy Halladay | ROK | sp | 29 | 32 | 4 | .125 | 0 | 19 | .594 | 177 | 5.5 | 17 | 1 | .059 |
| Brad Halsey* |   | mr | 25 | 7 | 0 | .000 | 0 | 1 | .143 | 34 | 4.9 | 33 | 5 | .152 |
| Cole Hamels* | WIZ | sp | 22 | 23 | 0 | .000 | 0 | 11 | .478 | 133 | 5.8 | 11 | 2 | .182 |
| Jason Hammel |   | sp | 23 | 9 | 0 | .000 | 0 | 1 | .111 | 34 | 3.8 | 7 | 2 | .286 |
| Chris Hammond* |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 8 | .889 |
| Justin Hampson* |   | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 20 | 20.0 | 3 | 0 | .000 |
| Tim Hamulack* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 |
| Josh Hancock | MUL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 |
| Devern Hansack |   | sp | 28 | 2 | 1 | .500 | 1 | 0 | .000 | 12 | 6.0 | 2 | 1 | .500 |
| Craig Hansen |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 11 | .550 |
| Aaron Harang | GEO | sp | 28 | 35 | 6 | .171 | 2 | 17 | .486 | 169 | 4.8 | 19 | 10 | .526 |
| Rich Harden | COP | sp | 24 | 9 | 0 | .000 | 0 | 2 | .222 | 61 | 6.8 | 8 | 4 | .500 |
| Dan Haren | LON | sp | 25 | 34 | 2 | .059 | 0 | 19 | .559 | 142 | 4.2 | 11 | 3 | .273 |
| Travis Harper |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 |
| Jeff Harris |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 |
| Chad Harville |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| LaTroy Hawkins |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 |
| Aaron Heilman | WIZ | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Rick Helling |   | mr | 35 | 2 | 0 | .000 | 0 | 0 | .000 | 1 | 0.5 | 1 | 1 | 1.000 |
| Ben Hendrickson |   | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 19 | 6.3 | 2 | 2 | 1.000 |
| Mark Hendrickson* | MUL | sp | 32 | 25 | 1 | .040 | 1 | 11 | .440 | 76 | 3.0 | 16 | 7 | .438 |
| Sean Henn* |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 2 | 2 | 1.000 |
| Brad Hennessey |   | mr | 26 | 12 | 0 | .000 | 0 | 3 | .250 | 52 | 4.3 | 15 | 5 | .333 |
| Clay Hensley | WIZ | sp | 26 | 29 | 1 | .034 | 1 | 17 | .586 | 120 | 4.1 | 13 | 3 | .231 |
| Matt Herges |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Dustin Hermanson |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Felix Hernandez | ROK | sp | 20 | 31 | 2 | .065 | 1 | 13 | .419 | 137 | 4.4 | 16 | 3 | .188 |
| Livan Hernandez |   | sp | 31 | 34 | 0 | .000 | 0 | 19 | .559 | 150 | 4.4 | 13 | 2 | .154 |
| Orlando Hernandez | Pal | sp | 36 | 29 | 1 | .034 | 0 | 15 | .517 | 144 | 5.0 | 15 | 7 | .467 |
| Roberto Hernandez |   | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 |
| Runelvys Hernandez |   | sp | 28 | 21 | 1 | .048 | 1 | 6 | .286 | 93 | 4.4 | 20 | 5 | .250 |
| Rich Hill* | BT | sp | 26 | 16 | 2 | .125 | 1 | 8 | .500 | 59 | 3.7 | 9 | 4 | .444 |
| Shawn Hill |   | sp | 25 | 6 | 0 | .000 | 0 | 4 | .667 | 19 | 3.2 | 2 | 2 | 1.000 |
| Jason Hirsh |   | sp | 24 | 9 | 0 | .000 | 0 | 4 | .444 | 50 | 5.6 | 13 | 7 | .538 |
| James Hoey |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Trevor Hoffman | Pal | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Mike Holtz* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| J.P. Howell* | MID | sp | 23 | 8 | 0 | .000 | 0 | 3 | .375 | 40 | 5.0 | 9 | 5 | .556 |
| Bob Howry | COP | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Jon Huber |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Luke Hudson | MID | sp | 29 | 15 | 0 | .000 | 0 | 9 | .600 | 85 | 5.7 | 18 | 15 | .833 |
| Tim Hudson | GEO | sp | 30 | 35 | 2 | .057 | 1 | 14 | .400 | 208 | 5.9 | 22 | 8 | .364 |
| Travis Hughes |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Philip Humber |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jason Isringhausen | Pal | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Edwin Jackson |   | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 10 | 2 | .200 |
| Zach Jackson* |   | sp | 23 | 7 | 0 | .000 | 0 | 1 | .143 | 37 | 5.3 | 7 | 1 | .143 |
| Chuck James* | Pal | sp | 24 | 18 | 0 | .000 | 0 | 11 | .611 | 103 | 5.7 | 5 | 2 | .400 |
| Casey Janssen | OTR | sp | 24 | 17 | 0 | .000 | 0 | 4 | .235 | 69 | 4.1 | 14 | 3 | .214 |
| Kevin Jarvis |   | mr | 36 | 4 | 0 | .000 | 0 | 0 | .000 | 19 | 4.8 | 2 | 0 | .000 |
| Bobby Jenks | OTR | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Jason Jennings | CCL | sp | 27 | 32 | 3 | .094 | 2 | 20 | .625 | 141 | 4.4 | 12 | 3 | .250 |
| Cesar Jimenez* |   | mr | 21 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 0 | 0 | .000 |
| Ubaldo Jimenez |   | sp | 22 | 1 | 0 | .000 | 0 | 1 | 1.000 | 5 | 5.0 | 2 | 2 | 1.000 |
| Jason Johnson |   | sp | 32 | 20 | 0 | .000 | 0 | 6 | .300 | 97 | 4.8 | 17 | 7 | .412 |
| Jim Johnson |   | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 0 | 0 | .000 |
| Josh Johnson | LON | sp | 22 | 24 | 0 | .000 | 0 | 14 | .583 | 138 | 5.8 | 12 | 1 | .083 |
| Randy Johnson* | ROK | sp | 42 | 33 | 2 | .061 | 0 | 14 | .424 | 208 | 6.3 | 12 | 5 | .417 |
| Tyler Johnson* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 5 | .179 |
| Greg Jones |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Todd Jones | MUL | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 |
| Jorge Julio |   | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 |
| Steve Karsay |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Jeff Karstens | BON | sp | 23 | 6 | 0 | .000 | 0 | 4 | .667 | 35 | 5.8 | 3 | 2 | .667 |
| Scott Kazmir* | GEO | sp | 22 | 24 | 1 | .042 | 1 | 11 | .458 | 94 | 3.9 | 12 | 4 | .333 |
| Randy Keisler* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 |
| Joe Kennedy* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 |
| Logan Kensing |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 |
| Bobby Keppel |   | sp | 24 | 6 | 0 | .000 | 0 | 2 | .333 | 14 | 2.3 | 7 | 2 | .286 |
| Byung-Hyun Kim |   | sp | 27 | 27 | 0 | .000 | 0 | 12 | .444 | 135 | 5.0 | 24 | 9 | .375 |
| Sun-Woo Kim |   | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 5 | 2 | .400 |
| Ray King* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 9 | .250 |
| Josh Kinney |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Steve Kline* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 6 | .146 |
| Dan Kolb |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 |
| Shane Komine |   | sp | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 13 | 6.5 | 2 | 0 | .000 |
| Mike Koplove |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| John Koronka* |   | sp | 25 | 23 | 0 | .000 | 0 | 10 | .435 | 125 | 5.4 | 12 | 2 | .167 |
| Hong-Chih Kuo* | Pal | mr | 24 | 5 | 0 | .000 | 0 | 3 | .600 | 25 | 5.0 | 15 | 10 | .667 |
| John Lackey | COP | sp | 27 | 33 | 3 | .091 | 2 | 23 | .697 | 161 | 4.9 | 11 | 1 | .091 |
| Juan Lara* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Brandon League | CRH | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 |
| Wilfredo Ledezma* |   | mr | 25 | 7 | 0 | .000 | 0 | 1 | .143 | 34 | 4.9 | 16 | 4 | .250 |
| Cliff Lee* | MID | sp | 27 | 33 | 1 | .030 | 0 | 14 | .424 | 192 | 5.8 | 19 | 4 | .211 |
| Justin Lehr |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Anthony Lerew |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jon Lester* | EDG | sp | 22 | 15 | 0 | .000 | 0 | 5 | .333 | 90 | 6.0 | 6 | 2 | .333 |
| Colby Lewis |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Brad Lidge | Pal | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 |
| Cory Lidle |   | sp | 34 | 30 | 0 | .000 | 0 | 18 | .600 | 158 | 5.3 | 16 | 7 | .438 |
| Jon Lieber |   | sp | 36 | 27 | 2 | .074 | 1 | 11 | .407 | 135 | 5.0 | 20 | 9 | .450 |
| Ted Lilly* | OTR | sp | 30 | 32 | 0 | .000 | 0 | 18 | .563 | 159 | 5.0 | 25 | 12 | .480 |
| Jose Lima |   | sp | 33 | 4 | 0 | .000 | 0 | 0 | .000 | 15 | 3.8 | 4 | 1 | .250 |
| Scott Linebrink |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Francisco Liriano* | ROK | sp | 22 | 16 | 0 | .000 | 0 | 10 | .625 | 72 | 4.5 | 6 | 1 | .167 |
| Wes Littleton |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 |
| Bobby Livingston* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Esteban Loaiza |   | sp | 34 | 26 | 2 | .077 | 1 | 10 | .385 | 127 | 4.9 | 20 | 4 | .200 |
| Kameron Loe |   | sp | 24 | 15 | 1 | .067 | 1 | 6 | .400 | 72 | 4.8 | 9 | 3 | .333 |
| Adam Loewen* | MID | sp | 22 | 19 | 0 | .000 | 0 | 4 | .211 | 81 | 4.3 | 18 | 11 | .611 |
| Boone Logan* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 |
| Kyle Lohse | MID | sp | 27 | 19 | 0 | .000 | 0 | 8 | .421 | 88 | 4.6 | 18 | 4 | .222 |
| Braden Looper | MAD | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 10 | .476 |
| Javier Lopez* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 |
| Rodrigo Lopez |   | sp | 30 | 29 | 0 | .000 | 0 | 8 | .276 | 133 | 4.6 | 28 | 11 | .393 |
| Derek Lowe | BON | sp | 33 | 34 | 1 | .029 | 0 | 20 | .588 | 162 | 4.8 | 21 | 8 | .381 |
| Mark Lowe |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Noah Lowry* |   | sp | 25 | 27 | 1 | .037 | 1 | 14 | .519 | 145 | 5.4 | 15 | 12 | .800 |
| Ruddy Lugo | GEO | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 12 | .571 |
| Brandon Lyon | Pal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Chris Mabeus |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Mike MacDougal |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 |
| Greg Maddux | Pal | sp | 40 | 34 | 0 | .000 | 0 | 17 | .500 | 149 | 4.4 | 18 | 7 | .389 |
| Ryan Madson | CCL | mr | 25 | 17 | 0 | .000 | 0 | 7 | .412 | 106 | 6.2 | 36 | 15 | .417 |
| Ron Mahay* |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 5 | .161 |
| Paul Maholm* |   | sp | 24 | 30 | 0 | .000 | 0 | 16 | .533 | 144 | 4.8 | 11 | 3 | .273 |
| John Maine | BT | sp | 25 | 15 | 1 | .067 | 1 | 9 | .600 | 70 | 4.7 | 8 | 2 | .250 |
| Gary Majewski |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 |
| Julio Manon |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 |
| Shaun Marcum | COP | sp | 24 | 14 | 0 | .000 | 0 | 4 | .286 | 52 | 3.7 | 10 | 1 | .100 |
| Carlos Marmol | WIZ | sp | 23 | 13 | 0 | .000 | 0 | 4 | .308 | 55 | 4.2 | 13 | 5 | .385 |
| Mike Maroth* |   | sp | 28 | 9 | 0 | .000 | 0 | 5 | .556 | 37 | 4.1 | 7 | 2 | .286 |
| Jason Marquis |   | sp | 27 | 33 | 0 | .000 | 0 | 13 | .394 | 156 | 4.7 | 21 | 9 | .429 |
| Sean Marshall* | LON | sp | 23 | 24 | 0 | .000 | 0 | 9 | .375 | 114 | 4.8 | 18 | 7 | .389 |
| Damaso Marte* | WIZ | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 10 | .244 |
| Tom Martin* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 14 | .378 |
| Carlos Martinez |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Pedro Martinez | WIZ | sp | 34 | 23 | 0 | .000 | 0 | 13 | .565 | 96 | 4.2 | 6 | 2 | .333 |
| Nick Masset |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Tom Mastny |   | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Juan Mateo |   | sp | 23 | 10 | 0 | .000 | 0 | 1 | .100 | 44 | 4.4 | 5 | 2 | .400 |
| Julio Mateo |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 |
| Scott Mathieson |   | sp | 22 | 8 | 0 | .000 | 0 | 1 | .125 | 41 | 5.1 | 5 | 1 | .200 |
| Joe Mays |   | sp | 30 | 10 | 0 | .000 | 0 | 1 | .100 | 53 | 5.3 | 12 | 2 | .167 |
| Macay McBride* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 13 | .342 |
| Brandon McCarthy |   | mr | 22 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 24 | 9 | .375 |
| Seth McClung |   | mr | 25 | 15 | 0 | .000 | 0 | 5 | .333 | 54 | 3.6 | 14 | 10 | .714 |
| Dustin McGowan |   | mr | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 14 | 4.7 | 13 | 7 | .538 |
| Marty McLeary |   | mr | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 4 | 2.0 | 0 | 0 | .000 |
| Brian Meadows |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Gil Meche | CRH | sp | 27 | 32 | 1 | .031 | 0 | 15 | .469 | 167 | 5.2 | 26 | 12 | .462 |
| Brandon Medders |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 |
| Kent Mercker* |   | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Cla Meredith | WIZ | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Jose Mesa |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 |
| Randy Messenger |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 |
| Dan Miceli |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Chris Michalak* |   | sp | 35 | 6 | 0 | .000 | 0 | 1 | .167 | 17 | 2.8 | 8 | 2 | .250 |
| Andrew Miller* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 5 | 1.000 |
| Matt Miller |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Trever Miller* | CCL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 6 | .200 |
| Wade Miller |   | sp | 29 | 5 | 0 | .000 | 0 | 0 | .000 | 22 | 4.4 | 1 | 1 | 1.000 |
| Kevin Millwood | CCL | sp | 31 | 34 | 2 | .059 | 0 | 22 | .647 | 168 | 4.9 | 14 | 9 | .643 |
| Eric Milton* |   | sp | 30 | 26 | 0 | .000 | 0 | 14 | .538 | 137 | 5.3 | 13 | 6 | .462 |
| Zach Miner |   | sp | 24 | 16 | 1 | .063 | 0 | 6 | .375 | 91 | 5.7 | 15 | 5 | .333 |
| Patrick Misch* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Sergio Mitre |   | sp | 25 | 7 | 0 | .000 | 0 | 2 | .286 | 33 | 4.7 | 9 | 6 | .667 |
| Brian Moehler |   | sp | 34 | 21 | 0 | .000 | 0 | 7 | .333 | 93 | 4.4 | 14 | 9 | .643 |
| Agustin Montero |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Juan Morillo |   | sp | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 0 | 0 | .000 |
| Matt Morris | CCL | sp | 31 | 33 | 2 | .061 | 0 | 16 | .485 | 136 | 4.1 | 18 | 7 | .389 |
| Dustin Moseley |   | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 20 | 10.0 | 0 | 0 | .000 |
| Guillermo Mota |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Jamie Moyer* |   | sp | 43 | 33 | 2 | .061 | 1 | 19 | .576 | 146 | 4.4 | 18 | 5 | .278 |
| Peter Moylan |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Edward Mujica |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Mark Mulder* |   | sp | 28 | 17 | 0 | .000 | 0 | 8 | .471 | 91 | 5.4 | 15 | 4 | .267 |
| Terry Mulholland* |   | mr | 43 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Scott Munter |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 |
| Mike Mussina | GEO | sp | 37 | 32 | 1 | .031 | 0 | 23 | .719 | 181 | 5.7 | 10 | 1 | .100 |
| Brett Myers | Pal | sp | 25 | 31 | 1 | .032 | 0 | 22 | .710 | 134 | 4.3 | 14 | 5 | .357 |
| Mike Myers* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 3 | .075 |
| Clint Nageotte |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chris Narveson* |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 3 | 0 | .000 |
| Joe Nathan | WIZ | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jeff Nelson |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Joe Nelson |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Pat Neshek |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 |
| Fernando Nieve |   | mr | 23 | 11 | 0 | .000 | 0 | 2 | .182 | 56 | 5.1 | 18 | 2 | .111 |
| Dustin Nippert |   | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 0 | 0 | .000 |
| Ricky Nolasco |   | sp | 23 | 22 | 0 | .000 | 0 | 13 | .591 | 99 | 4.5 | 21 | 8 | .381 |
| Roberto Novoa |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 |
| Leo Nunez |   | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Mike O'Connor* | BT | sp | 25 | 20 | 0 | .000 | 0 | 6 | .300 | 86 | 4.3 | 11 | 9 | .818 |
| Eric O'Flaherty* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 |
| Ryan O'Malley* |   | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 4 | 2.0 | 0 | 0 | .000 |
| Tomo Ohka |   | sp | 30 | 18 | 0 | .000 | 0 | 7 | .389 | 80 | 4.4 | 7 | 4 | .571 |
| Will Ohman* | MAD | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 |
| Darren Oliver* |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Scott Olsen* | TON | sp | 22 | 31 | 0 | .000 | 0 | 18 | .581 | 139 | 4.5 | 19 | 9 | .474 |
| Ramon Ortiz |   | sp | 33 | 33 | 0 | .000 | 0 | 15 | .455 | 136 | 4.1 | 22 | 9 | .409 |
| Russ Ortiz |   | mr | 32 | 11 | 0 | .000 | 0 | 1 | .091 | 45 | 4.1 | 12 | 3 | .250 |
| Chad Orvella |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 |
| Franquelis Osoria |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 |
| Roy Oswalt | BT | sp | 28 | 32 | 2 | .063 | 0 | 25 | .781 | 164 | 5.1 | 16 | 2 | .125 |
| Akinori Otsuka | MAD | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Henry Owens |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Vicente Padilla |   | sp | 28 | 33 | 0 | .000 | 0 | 20 | .606 | 181 | 5.5 | 23 | 9 | .391 |
| Jonathan Papelbon | BON | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| Chan Ho Park |   | sp | 33 | 21 | 1 | .048 | 1 | 9 | .429 | 109 | 5.2 | 14 | 4 | .286 |
| Chad Paronto | CCL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 3 | .150 |
| John Patterson |   | sp | 28 | 8 | 0 | .000 | 0 | 4 | .500 | 42 | 5.3 | 1 | 1 | 1.000 |
| David Pauley |   | sp | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 15 | 5.0 | 6 | 2 | .333 |
| Jake Peavy | MUL | sp | 25 | 32 | 2 | .063 | 0 | 21 | .656 | 139 | 4.3 | 9 | 4 | .444 |
| Mike Pelfrey |   | sp | 22 | 4 | 0 | .000 | 0 | 1 | .250 | 34 | 8.5 | 1 | 1 | 1.000 |
| Tony Pena |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Hayden Penn |   | sp | 21 | 6 | 0 | .000 | 0 | 1 | .167 | 13 | 2.2 | 9 | 3 | .333 |
| Brad Penny | LON | sp | 28 | 33 | 0 | .000 | 0 | 16 | .485 | 179 | 5.4 | 11 | 2 | .182 |
| Joel Peralta |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Beltran Perez |   | mr | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 16 | 5.3 | 1 | 0 | .000 |
| Juan Perez* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Odalis Perez* |   | sp | 29 | 20 | 0 | .000 | 0 | 7 | .350 | 112 | 5.6 | 13 | 5 | .385 |
| Oliver Perez* |   | sp | 24 | 22 | 1 | .045 | 1 | 7 | .318 | 99 | 4.5 | 16 | 7 | .438 |
| Rafael Perez* |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 |
| Glen Perkins* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Yusmeiro Petit |   | mr | 21 | 1 | 0 | .000 | 0 | 0 | .000 | 18 | 18.0 | 8 | 3 | .375 |
| Andy Pettitte* |   | sp | 34 | 35 | 2 | .057 | 1 | 20 | .571 | 155 | 4.4 | 19 | 4 | .211 |
| Joel Pineiro |   | sp | 27 | 25 | 1 | .040 | 0 | 10 | .400 | 124 | 5.0 | 30 | 16 | .533 |
| Renyel Pinto* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 |
| Cliff Politte |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 |
| Sidney Ponson |   | sp | 29 | 16 | 0 | .000 | 0 | 6 | .375 | 87 | 5.4 | 21 | 11 | .524 |
| Mark Prior |   | sp | 25 | 9 | 0 | .000 | 0 | 1 | .111 | 32 | 3.6 | 10 | 0 | .000 |
| Scott Proctor | EDG | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 4 | .174 |
| J.J. Putz | MID | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Chad Qualls | LON | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 |
| Brad Radke | BON | sp | 33 | 28 | 0 | .000 | 0 | 13 | .464 | 138 | 4.9 | 5 | 0 | .000 |
| Elizardo Ramirez |   | sp | 23 | 19 | 0 | .000 | 0 | 10 | .526 | 88 | 4.6 | 9 | 0 | .000 |
| Horacio Ramirez* | MUL | sp | 26 | 14 | 0 | .000 | 0 | 8 | .571 | 76 | 5.4 | 12 | 5 | .417 |
| Ramon Ramirez | LON | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 11 | .500 |
| Santiago Ramirez |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Darrell Rasner |   | sp | 25 | 3 | 0 | .000 | 0 | 2 | .667 | 18 | 6.0 | 2 | 2 | 1.000 |
| Jon Rauch |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 |
| Chris Ray | MID | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Ken Ray |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 |
| Britt Reames |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Mark Redman* |   | sp | 32 | 29 | 2 | .069 | 1 | 11 | .379 | 135 | 4.7 | 21 | 6 | .286 |
| Chris Reitsma |   | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 |
| Mike Remlinger* |   | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 |
| Chris Resop |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| Anthony Reyes |   | sp | 24 | 17 | 1 | .059 | 0 | 5 | .294 | 60 | 3.5 | 9 | 3 | .333 |
| Dennys Reyes* | BON | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 3 | .091 |
| John Rheinecker* |   | sp | 27 | 13 | 0 | .000 | 0 | 4 | .308 | 53 | 4.1 | 18 | 5 | .278 |
| Arthur Rhodes* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 |
| Juan Rincon | COP | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Ricardo Rincon* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Royce Ring* |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| David Riske | CRH | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 |
| Mariano Rivera | ROK | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Saul Rivera |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 2 | .095 |
| Sendy Rleal |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 |
| Nate Robertson* |   | sp | 28 | 32 | 1 | .031 | 0 | 20 | .625 | 125 | 3.9 | 17 | 10 | .588 |
| Fernando Rodney | OTR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 9 | .900 |
| Eddy Rodriguez |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Felix Rodriguez |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 |
| Francisco Rodriguez | BON | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Wandy Rodriguez* |   | sp | 27 | 24 | 0 | .000 | 0 | 9 | .375 | 119 | 5.0 | 24 | 9 | .375 |
| Brian Rogers |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 |
| Kenny Rogers* | EDG | sp | 41 | 33 | 0 | .000 | 0 | 19 | .576 | 195 | 5.9 | 16 | 6 | .375 |
| Davis Romero* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 |
| J.C. Romero* |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 13 | .382 |
| Matt Roney |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Francisco Rosario |   | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 6 | 3 | .500 |
| Josh Rupe |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 |
| Glendon Rusch* |   | mr | 31 | 9 | 0 | .000 | 0 | 1 | .111 | 41 | 4.6 | 11 | 6 | .545 |
| B.J. Ryan* | MID | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jae Kuk Ryu |   | mr | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 12 | 12.0 | 3 | 0 | .000 |
| Kirk Saarloos |   | mr | 27 | 16 | 0 | .000 | 0 | 7 | .438 | 81 | 5.1 | 13 | 3 | .231 |
| C.C. Sabathia* | CRH | sp | 25 | 28 | 6 | .214 | 2 | 18 | .643 | 118 | 4.2 | 7 | 6 | .857 |
| Billy Sadler |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Takashi Saito | Pal | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 |
| Juan Salas |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Chris Sampson |   | mr | 28 | 3 | 0 | .000 | 0 | 1 | .333 | 7 | 2.3 | 3 | 0 | .000 |
| Brian Sanches |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Anibal Sanchez | MAD | sp | 22 | 17 | 2 | .118 | 1 | 13 | .765 | 75 | 4.4 | 6 | 3 | .500 |
| Duaner Sanchez | MAD | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Jonathan Sanchez* |   | mr | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 28 | 7.0 | 20 | 1 | .050 |
| Ervin Santana | BON | sp | 23 | 33 | 0 | .000 | 0 | 18 | .545 | 181 | 5.5 | 14 | 6 | .429 |
| Johan Santana* | ROK | sp | 27 | 34 | 1 | .029 | 0 | 24 | .706 | 174 | 5.1 | 9 | 4 | .444 |
| Julio Santana |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Victor Santos |   | sp | 29 | 19 | 0 | .000 | 0 | 7 | .368 | 90 | 4.7 | 12 | 5 | .417 |
| Dennis Sarfate |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 |
| Scott Sauerbeck* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 9 | .281 |
| Joe Saunders* | MID | sp | 25 | 13 | 0 | .000 | 0 | 8 | .615 | 72 | 5.5 | 9 | 6 | .667 |
| Curt Schilling | CRH | sp | 39 | 31 | 0 | .000 | 0 | 19 | .613 | 159 | 5.1 | 8 | 2 | .250 |
| Jason Schmidt | WIZ | sp | 33 | 32 | 3 | .094 | 1 | 20 | .625 | 137 | 4.3 | 14 | 6 | .429 |
| Scott Schoeneweis* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 12 | .343 |
| Chris Schroder |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Rudy Seanez |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 |
| Bobby Seay* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 |
| Aaron Sele |   | sp | 36 | 15 | 0 | .000 | 0 | 9 | .600 | 93 | 6.2 | 11 | 4 | .364 |
| Jae Seo |   | sp | 29 | 26 | 0 | .000 | 0 | 13 | .500 | 106 | 4.1 | 17 | 4 | .235 |
| Brian Shackelford* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 |
| Josh Sharpless |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 |
| Ben Sheets | TON | sp | 27 | 17 | 0 | .000 | 0 | 11 | .647 | 62 | 3.6 | 5 | 4 | .800 |
| George Sherrill* | ROK | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 66 | 18 | .273 |
| James Shields | BON | sp | 24 | 21 | 1 | .048 | 0 | 11 | .524 | 86 | 4.1 | 11 | 3 | .273 |
| Scot Shields | ROK | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Jason Shiell |   | sp | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 2 | 0 | .000 |
| Brian Shouse* | OTR | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 7 | .152 |
| Brian Sikorski |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 |
| Carlos Silva |   | sp | 27 | 31 | 0 | .000 | 0 | 10 | .323 | 169 | 5.5 | 26 | 13 | .500 |
| Allan Simpson |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Andrew Sisco* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 14 | .341 |
| Doug Slaten* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Brian Slocum |   | mr | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 3 | 0 | .000 |
| Aaron Small |   | mr | 34 | 3 | 0 | .000 | 0 | 0 | .000 | 18 | 6.0 | 9 | 5 | .556 |
| Matt Smith* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Mike Smith |   | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 0 | 0 | .000 |
| Travis Smith |   | sp | 33 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 |
| John Smoltz | WIZ | sp | 39 | 35 | 3 | .086 | 1 | 24 | .686 | 176 | 5.0 | 5 | 3 | .600 |
| Ian Snell |   | sp | 24 | 32 | 0 | .000 | 0 | 14 | .438 | 150 | 4.7 | 13 | 5 | .385 |
| Kyle Snyder |   | sp | 28 | 11 | 0 | .000 | 0 | 1 | .091 | 52 | 4.7 | 11 | 6 | .545 |
| Alay Soler |   | sp | 26 | 8 | 1 | .125 | 1 | 4 | .500 | 35 | 4.4 | 1 | 1 | 1.000 |
| Rafael Soriano | GEO | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Jorge Sosa |   | mr | 29 | 13 | 0 | .000 | 0 | 4 | .308 | 54 | 4.2 | 15 | 3 | .200 |
| Jeremy Sowers* | EDG | sp | 23 | 14 | 2 | .143 | 2 | 8 | .571 | 69 | 4.9 | 4 | 2 | .500 |
| Justin Speier | MID | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 4 | .133 |
| Russ Springer | WIZ | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 |
| Chris Spurling |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 |
| Jason Standridge |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 |
| Mike Stanton* |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 5 | .161 |
| Tim Stauffer | MAD | sp | 24 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 |
| Steve Stemle |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 |
| Phil Stockman |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Brian Stokes |   | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 22 | 5.5 | 0 | 0 | .000 |
| Huston Street | GEO | cl | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 |
| Eric Stults* |   | mr | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 13 | 6.5 | 1 | 1 | 1.000 |
| Tanyon Sturtze |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 |
| Jeff Suppan |   | sp | 31 | 32 | 0 | .000 | 0 | 18 | .563 | 153 | 4.8 | 21 | 6 | .286 |
| Brian Sweeney | MUL | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 |
| Jon Switzer* |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 |
| Brian Tallet* |   | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 24 | 12 | .500 |
| Taylor Tankersley* | MAD | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 |
| Jack Taschner* |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 |
| Jordan Tata |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 |
| Ty Taubenheim |   | sp | 23 | 7 | 0 | .000 | 0 | 1 | .143 | 25 | 3.6 | 8 | 0 | .000 |
| Julian Tavarez |   | mr | 33 | 6 | 1 | .167 | 0 | 2 | .333 | 34 | 5.7 | 17 | 7 | .412 |
| Robinson Tejeda |   | sp | 24 | 14 | 0 | .000 | 0 | 6 | .429 | 58 | 4.1 | 11 | 2 | .182 |
| Brad Thompson |   | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 8 | 2 | .250 |
| Mike Thompson |   | sp | 25 | 16 | 0 | .000 | 0 | 8 | .500 | 74 | 4.6 | 14 | 4 | .286 |
| John Thomson |   | sp | 32 | 15 | 0 | .000 | 0 | 4 | .267 | 78 | 5.2 | 14 | 3 | .214 |
| Matt Thornton* | CRH | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 9 | .257 |
| Mike Timlin | OTR | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 |
| Brett Tomko |   | mr | 33 | 15 | 0 | .000 | 0 | 7 | .467 | 73 | 4.9 | 12 | 3 | .250 |
| Salomon Torres | CCL | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 12 | .444 |
| Josh Towers |   | sp | 29 | 12 | 0 | .000 | 0 | 1 | .083 | 58 | 4.8 | 12 | 6 | .500 |
| Billy Traber* |   | sp | 26 | 8 | 0 | .000 | 0 | 2 | .250 | 47 | 5.9 | 14 | 2 | .143 |
| Sean Tracey |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Steve Trachsel |   | sp | 35 | 30 | 1 | .033 | 0 | 13 | .433 | 165 | 5.5 | 31 | 8 | .258 |
| Derrick Turnbow |   | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 15 | .682 |
| Jose Valverde | WIZ | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Jermaine Van Buren |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 9 | .750 |
| Claudio Vargas |   | sp | 28 | 30 | 0 | .000 | 0 | 16 | .533 | 140 | 4.7 | 28 | 8 | .286 |
| Jason Vargas* |   | mr | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 34 | 6.8 | 5 | 2 | .400 |
| Javier Vazquez | Pal | sp | 29 | 32 | 1 | .031 | 0 | 14 | .438 | 177 | 5.5 | 25 | 13 | .520 |
| Mike Venafro* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 |
| Jose Veras |   | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Justin Verlander | COP | sp | 23 | 30 | 1 | .033 | 1 | 18 | .600 | 169 | 5.6 | 10 | 6 | .600 |
| Carlos Villanueva | TON | sp | 22 | 6 | 0 | .000 | 0 | 3 | .500 | 20 | 3.3 | 3 | 1 | .333 |
| Oscar Villarreal |   | mr | 24 | 4 | 0 | .000 | 0 | 0 | .000 | 25 | 6.3 | 14 | 1 | .071 |
| Ron Villone* |   | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 16 | .485 |
| Luis Vizcaino | LON | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 |
| Ryan Vogelsong |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 |
| Edinson Volquez |   | sp | 22 | 8 | 0 | .000 | 0 | 1 | .125 | 30 | 3.8 | 7 | 1 | .143 |
| Doug Waechter |   | sp | 25 | 10 | 0 | .000 | 0 | 2 | .200 | 42 | 4.2 | 12 | 6 | .500 |
| Billy Wagner* | BT | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 |
| Ryan Wagner |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 |
| Adam Wainwright | MAD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 |
| Tim Wakefield | OTR | sp | 39 | 23 | 1 | .043 | 0 | 13 | .565 | 107 | 4.7 | 10 | 4 | .400 |
| Jamie Walker* | OTR | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 2 | .080 |
| Pete Walker |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 |
| Tyler Walker |   | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 6 | .750 |
| Les Walrond* |   | mr | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 8 | 0 | .000 |
| Chien-Ming Wang | COP | sp | 26 | 33 | 2 | .061 | 1 | 18 | .545 | 184 | 5.6 | 24 | 6 | .250 |
| John Wasdin |   | sp | 33 | 5 | 0 | .000 | 0 | 1 | .200 | 32 | 6.4 | 5 | 2 | .400 |
| Jarrod Washburn* |   | sp | 31 | 31 | 0 | .000 | 0 | 16 | .516 | 137 | 4.4 | 25 | 7 | .280 |
| David Weathers | TON | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 |
| Jeff Weaver |   | sp | 29 | 31 | 0 | .000 | 0 | 12 | .387 | 152 | 4.9 | 26 | 6 | .231 |
| Jered Weaver | OTR | sp | 23 | 19 | 0 | .000 | 0 | 14 | .737 | 93 | 4.9 | 7 | 1 | .143 |
| Brandon Webb | TON | sp | 27 | 33 | 5 | .152 | 3 | 23 | .697 | 170 | 5.2 | 9 | 1 | .111 |
| Todd Wellemeyer |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 10 | .417 |
| David Wells* | EDG | sp | 43 | 13 | 0 | .000 | 0 | 6 | .462 | 57 | 4.4 | 6 | 3 | .500 |
| Kip Wells |   | sp | 29 | 9 | 0 | .000 | 0 | 2 | .222 | 46 | 5.1 | 12 | 3 | .250 |
| Jake Westbrook | MID | sp | 28 | 32 | 3 | .094 | 2 | 18 | .563 | 177 | 5.5 | 14 | 11 | .786 |
| Dan Wheeler | Pal | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 |
| Rick White |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 8 | .615 |
| Bob Wickman | COP | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 |
| Dave Williams* |   | sp | 27 | 13 | 0 | .000 | 0 | 6 | .462 | 78 | 6.0 | 12 | 5 | .417 |
| Jerome Williams |   | mr | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 4 | 2.0 | 1 | 0 | .000 |
| Todd Williams |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 |
| Woody Williams | MUL | sp | 39 | 24 | 0 | .000 | 0 | 13 | .542 | 135 | 5.6 | 16 | 4 | .250 |
| Scott Williamson |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 8 | .500 |
| Dontrelle Willis* | MAD | sp | 24 | 34 | 4 | .118 | 1 | 20 | .588 | 129 | 3.8 | 26 | 3 | .115 |
| Brian Wilson |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 8 | .421 |
| C.J. Wilson* | ROK | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 |
| Kris Wilson |   | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 2 | 0 | .000 |
| Jason Windsor |   | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 2 | 0 | .000 |
| Joe Winkelsas |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 |
| Matt Wise |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 |
| Jay Witasick |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 7 | .467 |
| Randy Wolf* |   | sp | 29 | 12 | 0 | .000 | 0 | 2 | .167 | 80 | 6.7 | 7 | 4 | .571 |
| Kerry Wood | MUL | sp | 29 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 1 | 0 | .000 |
| Mike Wood |   | mr | 26 | 7 | 0 | .000 | 0 | 1 | .143 | 33 | 4.7 | 21 | 4 | .190 |
| Jake Woods* |   | mr | 24 | 8 | 0 | .000 | 0 | 2 | .250 | 32 | 4.0 | 21 | 4 | .190 |
| Tim Worrell |   | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 |
| Jamey Wright |   | sp | 31 | 21 | 0 | .000 | 0 | 9 | .429 | 98 | 4.7 | 19 | 14 | .737 |
| Jaret Wright |   | sp | 30 | 27 | 0 | .000 | 0 | 10 | .370 | 146 | 5.4 | 32 | 17 | .531 |
| Michael Wuertz | BT | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 1 | .053 |
| Esteban Yan |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 |
| Tyler Yates | TON | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 |
| Shane Youman* |   | sp | 26 | 3 | 0 | .000 | 0 | 1 | .333 | 5 | 1.7 | 3 | 2 | .667 |
| Chris Young | COP | sp | 27 | 31 | 0 | .000 | 0 | 18 | .581 | 131 | 4.2 | 18 | 7 | .389 |
| Carlos Zambrano | CCL | sp | 25 | 33 | 0 | .000 | 0 | 22 | .667 | 188 | 5.7 | 12 | 2 | .167 |
| Victor Zambrano |   | sp | 30 | 5 | 0 | .000 | 0 | 1 | .200 | 26 | 5.2 | 0 | 0 | .000 |
| Barry Zito* | EDG | sp | 28 | 34 | 0 | .000 | 0 | 20 | .588 | 150 | 4.4 | 13 | 2 | .154 |
| Joel Zumaya | ROK | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF |
| David Aardsma | BT | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 5 | 20 | 5 | .250 | 45 | 45 | 9 |
| Winston Abreu |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 7 | 7 | 2 |
| Jeremy Accardo |   | mr | 24 | 10 | 3 | .300 | 7 | .700 | 10 | 31 | 13 | .419 | 65 | 65 | 27 |
| Mike Adams | MUL | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 2 | 2 | 0 |
| Jon Adkins |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 8 | 18 | 5 | .278 | 55 | 55 | 15 |
| Jeremy Affeldt* | CRH | mr | 27 | 3 | 1 | .333 | 2 | .667 | 5 | 33 | 8 | .242 | 54 | 45 | 12 |
| Matt Albers |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 2 | 0 |
| Antonio Alfonseca |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 8 | 7 | 3 | .429 | 19 | 19 | 3 |
| Abe Alvarez* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 0 |
| Steve Andrade |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 4 | 4 | 2 |
| Greg Aquino |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 15 | 5 | .333 | 42 | 42 | 12 |
| Tony Armas |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Bronson Arroyo | BT | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 |
| Miguel Asencio |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 2 | 0 |
| Ezequiel Astacio |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 6 | 6 | 2 |
| Pedro Astacio |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| Brandon Backe |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Cha Seung Baek |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Danys Baez |   | mr | 28 | 17 | 9 | .529 | 8 | .471 | 12 | 25 | 10 | .400 | 57 | 57 | 28 |
| Jeff Bajenaru |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Scott Baker |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 |
| Brian Bannister |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 1 |
| Kevin Barry |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 4 | 2 | .500 | 19 | 18 | 7 |
| Phil Barzilla* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 0 |
| Miguel Batista |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 0 |
| Rick Bauer | EDG | mr | 29 | 5 | 2 | .400 | 3 | .600 | 8 | 40 | 13 | .325 | 58 | 57 | 19 |
| Denny Bautista |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 4 | 3 |
| Jonah Bayliss |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 3 | .750 | 11 | 11 | 5 |
| T.J. Beam |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 4 | .400 | 20 | 20 | 5 |
| Colter Bean |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Josh Beckett | Pal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Erik Bedard* | GEO | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Joe Beimel* |   | mr | 29 | 3 | 2 | .667 | 1 | .333 | 12 | 32 | 8 | .250 | 62 | 62 | 10 |
| Matt Belisle |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 3 | .375 | 30 | 28 | 5 |
| Heath Bell | MUL | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 7 | .636 | 22 | 22 | 6 |
| Armando Benitez |   | cl | 33 | 25 | 17 | .680 | 8 | .320 | 1 | 7 | 4 | .571 | 41 | 41 | 33 |
| Joaquin Benoit | OTR | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 7 | 44 | 10 | .227 | 56 | 56 | 7 |
| Kris Benson |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Jason Bergmann |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 7 | 4 | .571 | 29 | 23 | 7 |
| Adam Bernero |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 4 | 1 | 0 |
| Rafael Betancourt | GEO | mr | 31 | 6 | 3 | .500 | 3 | .500 | 7 | 27 | 7 | .259 | 50 | 50 | 17 |
| Chad Billingsley | TON | sp | 21 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 18 | 2 | 0 |
| Kurt Birkins* |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 6 | 24 | 5 | .208 | 35 | 35 | 4 |
| Joe Blanton | BON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 1 | 0 |
| Jeremy Bonderman | OTR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Boof Bonser | BON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 |
| Chris Booker |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 0 | .000 | 11 | 11 | 2 |
| Chris Bootcheck |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 4 | .500 | 7 | 7 | 5 |
| Dave Borkowski |   | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 1 | 8 | 6 | .750 | 40 | 40 | 12 |
| Joe Borowski |   | cl | 35 | 43 | 36 | .837 | 7 | .163 | 0 | 14 | 1 | .071 | 72 | 72 | 60 |
| Micah Bowie* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 5 | 3 | 1 | .333 | 15 | 15 | 3 |
| Blaine Boyer |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 2 | 2 | 0 |
| Chad Bradford | EDG | mr | 31 | 3 | 2 | .667 | 1 | .333 | 10 | 53 | 10 | .189 | 70 | 70 | 15 |
| Ryan Braun |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 0 | 3 | 2 | .667 | 9 | 9 | 2 |
| Bill Bray* |   | mr | 23 | 3 | 2 | .667 | 1 | .333 | 4 | 30 | 11 | .367 | 48 | 48 | 10 |
| Dewon Brazelton |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 9 | 7 | 3 |
| Yhency Brazoban |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 2 | .667 | 5 | 5 | 2 |
| Craig Breslow* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 12 | 4 | .333 | 13 | 13 | 3 |
| Eude Brito* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 5 | 3 | 0 |
| Chris Britton | OTR | mr | 23 | 4 | 1 | .250 | 3 | .750 | 6 | 20 | 4 | .200 | 52 | 52 | 12 |
| Doug Brocail |   | mr | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 25 | 25 | 6 |
| Jim Brower |   | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 1 | 7 | 5 | .714 | 18 | 18 | 4 |
| Andrew Brown |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 9 | 9 | 4 |
| Jonathan Broxton | CCL | mr | 22 | 7 | 3 | .429 | 4 | .571 | 12 | 25 | 7 | .280 | 68 | 68 | 20 |
| Brian Bruney |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 5 | 17 | 6 | .353 | 19 | 19 | 2 |
| Taylor Buchholz | MUL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 3 | 1 |
| Mark Buehrle* | GEO | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jason Bulger |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Ambiorix Burgos |   | cl | 22 | 30 | 18 | .600 | 12 | .400 | 5 | 41 | 21 | .512 | 68 | 67 | 41 |
| A.J. Burnett | TON | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| Mike Burns |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 6 | .667 | 18 | 18 | 6 |
| Brian Burres* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 4 | 10 | 1 | .100 | 11 | 11 | 2 |
| Dave Bush | OTR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 34 | 2 | 0 |
| Paul Byrd |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Tim Byrdak* |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 3 | 10 | 3 | .300 | 16 | 16 | 2 |
| Daniel Cabrera | CRH | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Fernando Cabrera |   | mr | 24 | 4 | 0 | .000 | 4 | 1.000 | 6 | 22 | 11 | .500 | 51 | 51 | 20 |
| Matt Cain | LON | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 1 | 1 |
| Kiko Calero | LON | mr | 31 | 6 | 2 | .333 | 4 | .667 | 24 | 45 | 12 | .267 | 70 | 70 | 17 |
| Shawn Camp |   | mr | 30 | 6 | 4 | .667 | 2 | .333 | 13 | 62 | 19 | .306 | 75 | 75 | 15 |
| Brett Campbell |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 2 |
| Jorge Campillo |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Jose Capellan |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 17 | 31 | 10 | .323 | 61 | 61 | 12 |
| Matt Capps | MUL | mr | 22 | 10 | 1 | .100 | 9 | .900 | 13 | 60 | 21 | .350 | 85 | 85 | 15 |
| Chris Capuano* | BT | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Fausto Carmona | GEO | mr | 22 | 3 | 0 | .000 | 3 | 1.000 | 10 | 6 | 1 | .167 | 38 | 31 | 12 |
| Chris Carpenter | CRH | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Giovanni Carrara |   | mr | 38 | 2 | 1 | .500 | 1 | .500 | 2 | 16 | 4 | .250 | 25 | 25 | 9 |
| Hector Carrasco | LON | mr | 36 | 2 | 1 | .500 | 1 | .500 | 2 | 19 | 7 | .368 | 56 | 53 | 24 |
| Lance Carter |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 2 | 1.000 | 10 | 10 | 2 |
| Santiago Casilla |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 |
| Scott Cassidy |   | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 4 | 25 | 12 | .480 | 42 | 42 | 14 |
| Fabio Castro* |   | mr | 21 | 2 | 1 | .500 | 1 | .500 | 1 | 9 | 3 | .333 | 20 | 20 | 11 |
| Gustavo Chacin* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| Shawn Chacon |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 26 | 6 | 0 |
| Bruce Chen* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 13 | 2 | .154 | 40 | 28 | 16 |
| Travis Chick |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 0 |
| Jason Childers |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 5 | 5 | 0 |
| Randy Choate* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 5 | 15 | 3 | .200 | 30 | 30 | 3 |
| Vinnie Chulk |   | mr | 27 | 3 | 0 | .000 | 3 | 1.000 | 6 | 29 | 12 | .414 | 48 | 48 | 13 |
| Brandon Claussen* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Roger Clemens | ROK | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 |
| Matt Clement |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| Todd Coffey |   | mr | 25 | 12 | 8 | .667 | 4 | .333 | 16 | 35 | 8 | .229 | 81 | 81 | 28 |
| Jesus Colome |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 0 |
| Bartolo Colon |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 |
| Roman Colon |   | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 4 | 14 | 4 | .286 | 20 | 19 | 4 |
| Clay Condrey |   | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 1 | 4 | 1 | .250 | 21 | 21 | 10 |
| Jose Contreras | GEO | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Aaron Cook | MAD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Roy Corcoran |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 6 | 6 | 2 |
| Tim Corcoran |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 21 | 5 | 2 |
| Chad Cordero |   | cl | 24 | 33 | 29 | .879 | 4 | .121 | 0 | 12 | 1 | .083 | 68 | 68 | 59 |
| Francisco Cordero | CRH | cl | 31 | 33 | 22 | .667 | 11 | .333 | 16 | 33 | 11 | .333 | 77 | 77 | 47 |
| Bryan Corey |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 3 | 15 | 4 | .267 | 32 | 32 | 3 |
| Lance Cormier |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 9 | 2 | .222 | 29 | 20 | 5 |
| Rheal Cormier* |   | mr | 39 | 4 | 0 | .000 | 4 | 1.000 | 14 | 48 | 20 | .417 | 64 | 64 | 13 |
| Manuel Corpas |   | mr | 23 | 2 | 0 | .000 | 2 | 1.000 | 7 | 29 | 5 | .172 | 35 | 35 | 3 |
| Kevin Correia | MUL | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 11 | 39 | 13 | .333 | 48 | 48 | 9 |
| David Cortes |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 3 | 17 | 3 | .176 | 30 | 30 | 16 |
| Neal Cotts* |   | mr | 26 | 4 | 1 | .250 | 3 | .750 | 14 | 67 | 19 | .284 | 70 | 70 | 14 |
| Jesse Crain | GEO | mr | 24 | 4 | 1 | .250 | 3 | .750 | 10 | 34 | 13 | .382 | 68 | 68 | 24 |
| Francisco Cruceta |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 4 | 3 | 1 |
| Juan Cruz | TON | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 0 | .000 | 31 | 16 | 5 |
| Casey Daigle |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 3 | 0 | .000 | 10 | 10 | 1 |
| Kyle Davies |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Doug Davis* |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Jason Davis |   | mr | 26 | 3 | 1 | .333 | 2 | .667 | 8 | 21 | 15 | .714 | 39 | 39 | 10 |
| Zach Day |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Jorge De La Rosa* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 28 | 15 | 4 |
| Mike DeJean |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 2 | 2 | 1 |
| Manny Delcarmen |   | mr | 24 | 4 | 0 | .000 | 4 | 1.000 | 14 | 31 | 19 | .613 | 50 | 50 | 11 |
| Chris Demaria |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 10 | 10 | 4 |
| Ryan Dempster | CRH | cl | 29 | 33 | 24 | .727 | 9 | .273 | 2 | 6 | 0 | .000 | 74 | 74 | 64 |
| Elmer Dessens |   | mr | 35 | 7 | 2 | .286 | 5 | .714 | 18 | 42 | 15 | .357 | 62 | 62 | 12 |
| Joey Devine |   | mr | 22 | 1 | 0 | .000 | 1 | 1.000 | 0 | 9 | 3 | .333 | 10 | 10 | 1 |
| Jose Diaz |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 4 | 4 | 1 |
| R.A. Dickey | OTR | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Lenny DiNardo* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 13 | 7 | 0 |
| Scott Dohmann |   | mr | 28 | 3 | 1 | .333 | 2 | .667 | 7 | 32 | 7 | .219 | 48 | 48 | 18 |
| Brendan Donnelly | CRH | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 11 | 32 | 11 | .344 | 62 | 62 | 17 |
| Octavio Dotel |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 4 | .800 | 14 | 14 | 7 |
| Scott Downs* | EDG | mr | 30 | 4 | 1 | .250 | 3 | .750 | 7 | 39 | 11 | .282 | 59 | 54 | 13 |
| Ryan Drese |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Eric DuBose* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 0 |
| Justin Duchscherer | COP | mr | 28 | 11 | 9 | .818 | 2 | .182 | 17 | 22 | 3 | .136 | 53 | 53 | 17 |
| Brandon Duckworth |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 2 | 0 |
| Zach Duke* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Scott Dunn |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 2 | 6 | 4 | .667 | 7 | 7 | 0 |
| Chad Durbin |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 1 |
| Adam Eaton |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Joey Eischen* |   | mr | 36 | 1 | 0 | .000 | 1 | 1.000 | 0 | 23 | 5 | .217 | 22 | 22 | 4 |
| Scott Elarton |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 |
| Alan Embree* | LON | mr | 36 | 0 | 0 | .000 | 0 | .000 | 16 | 45 | 11 | .244 | 73 | 73 | 11 |
| Scott Erickson |   | mr | 38 | 0 | 0 | .000 | 0 | .000 | 2 | 2 | 2 | 1.000 | 9 | 9 | 2 |
| Kelvim Escobar | COP | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Shawn Estes* |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Seth Etherton |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Dana Eveland* |   | sp | 22 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 3 | .750 | 9 | 4 | 1 |
| Scott Eyre* |   | mr | 34 | 3 | 0 | .000 | 3 | 1.000 | 18 | 42 | 9 | .214 | 74 | 74 | 15 |
| Willie Eyre |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 22 | 5 | .227 | 42 | 42 | 20 |
| Brian Falkenborg |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 5 | 5 | 3 |
| Kyle Farnsworth | BON | mr | 30 | 10 | 6 | .600 | 4 | .400 | 19 | 22 | 8 | .364 | 72 | 72 | 24 |
| Jeff Fassero* |   | mr | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 10 | 9 | 2 |
| Ryan Feierabend* |   | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 2 | 2 |
| Scott Feldman | MID | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 8 | 15 | 5 | .333 | 36 | 36 | 5 |
| Pedro Feliciano* | MAD | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 10 | 39 | 12 | .308 | 64 | 64 | 10 |
| Jared Fernandez |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 4 | 4 | 3 |
| Nate Field |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 4 | 22 | 12 | .545 | 14 | 14 | 1 |
| Randy Flores* |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 18 | 39 | 14 | .359 | 65 | 65 | 10 |
| Ron Flores* |   | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 18 | 11 | .611 | 25 | 25 | 11 |
| Gavin Floyd | TON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 |
| Josh Fogg |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Bartolome Fortunato |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 0 |
| Casey Fossum* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 |
| Keith Foulke |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 14 | 18 | 5 | .278 | 44 | 44 | 16 |
| Jeff Francis* | MAD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Frank Francisco |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 0 | 0 | .000 | 8 | 8 | 2 |
| Ryan Franklin |   | mr | 33 | 3 | 0 | .000 | 3 | 1.000 | 9 | 24 | 6 | .250 | 66 | 66 | 19 |
| Wayne Franklin* |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 1 | .111 | 11 | 11 | 3 |
| Jason Frasor | MID | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 13 | 37 | 18 | .486 | 51 | 51 | 12 |
| Emiliano Fruto |   | mr | 22 | 3 | 1 | .333 | 2 | .667 | 2 | 15 | 5 | .333 | 23 | 23 | 6 |
| Brian Fuentes* | CCL | cl | 30 | 36 | 30 | .833 | 6 | .167 | 0 | 16 | 1 | .063 | 66 | 66 | 58 |
| Jeff Fulchino |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 0 |
| Aaron Fultz* | MAD | mr | 32 | 2 | 0 | .000 | 2 | 1.000 | 11 | 58 | 23 | .397 | 66 | 65 | 12 |
| Kason Gabbard* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 3 | 1 |
| Eric Gagne |   | cl | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 2 |
| Mike Gallo* |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 2 | .286 | 23 | 23 | 7 |
| Freddy Garcia | EDG | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jose Garcia |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 5 | 5 | 1 |
| Jon Garland | COP | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 33 | 1 | 0 |
| Matt Garza | GEO | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 10 | 1 | 0 |
| Chad Gaudin |   | mr | 23 | 3 | 2 | .667 | 1 | .333 | 11 | 35 | 7 | .200 | 55 | 55 | 13 |
| Geoff Geary |   | mr | 29 | 4 | 1 | .250 | 3 | .750 | 15 | 40 | 13 | .325 | 81 | 81 | 17 |
| Franklyn German |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 3 | 2 | .667 | 12 | 12 | 3 |
| Justin Germano |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 1 | 0 |
| Tom Glavine* | WIZ | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jimmy Gobble* |   | mr | 24 | 4 | 2 | .500 | 2 | .500 | 11 | 48 | 12 | .250 | 60 | 54 | 17 |
| Edgar Gonzalez |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 11 | 6 | 1 |
| Enrique Gonzalez | CCL | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 22 | 4 | 1 |
| Geremi Gonzalez |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 5 | 3 | .600 | 24 | 20 | 3 |
| Mike Gonzalez* | BT | cl | 28 | 24 | 24 | 1.000 | 0 | .000 | 3 | 2 | 2 | 1.000 | 54 | 54 | 47 |
| Tom Gordon | BT | cl | 38 | 39 | 34 | .872 | 5 | .128 | 0 | 18 | 7 | .389 | 59 | 59 | 53 |
| Tom Gorzelanny* | LON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 |
| Mike Gosling* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| John Grabow* |   | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 11 | 40 | 7 | .175 | 72 | 72 | 17 |
| Danny Graves |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 3 | .375 | 13 | 13 | 5 |
| Sean Green |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 3 | 22 | 6 | .273 | 24 | 24 | 11 |
| Kevin Gregg |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 14 | 8 | .571 | 32 | 29 | 12 |
| Zack Greinke | COP | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 3 | 1 |
| Jason Grilli |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 9 | 37 | 10 | .270 | 51 | 51 | 18 |
| Jason Grimsley |   | mr | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 17 | 5 | .294 | 19 | 19 | 6 |
| Kevin Gryboski |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 1 | 1.000 | 6 | 6 | 1 |
| Eddie Guardado* |   | cl | 35 | 18 | 13 | .722 | 5 | .278 | 2 | 6 | 4 | .667 | 43 | 43 | 26 |
| Matt Guerrier |   | mr | 27 | 2 | 1 | .500 | 1 | .500 | 2 | 17 | 9 | .529 | 39 | 38 | 13 |
| Jeremy Guthrie |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 9 | 8 | 1 |
| Angel Guzman |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 15 | 5 | 1 |
| Charlie Haeger |   | mr | 22 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 1 | .167 | 7 | 6 | 4 |
| John Halama* |   | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 0 | 14 | 5 | .357 | 17 | 16 | 7 |
| Roy Halladay | ROK | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Brad Halsey* |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 8 | 24 | 9 | .375 | 52 | 45 | 7 |
| Cole Hamels* | WIZ | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 |
| Jason Hammel |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Chris Hammond* |   | mr | 40 | 2 | 0 | .000 | 2 | 1.000 | 6 | 10 | 4 | .400 | 29 | 29 | 7 |
| Justin Hampson* |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 3 | .750 | 5 | 4 | 0 |
| Tim Hamulack* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 4 | 15 | 3 | .200 | 33 | 33 | 12 |
| Josh Hancock | MUL | mr | 28 | 3 | 1 | .333 | 2 | .667 | 7 | 50 | 20 | .400 | 62 | 62 | 15 |
| Devern Hansack |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Craig Hansen |   | mr | 22 | 2 | 0 | .000 | 2 | 1.000 | 8 | 18 | 3 | .167 | 38 | 38 | 11 |
| Aaron Harang | GEO | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 1 | 0 |
| Rich Harden | COP | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Dan Haren | LON | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Travis Harper |   | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 6 | 20 | 9 | .450 | 30 | 30 | 7 |
| Jeff Harris |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Chad Harville |   | mr | 29 | 2 | 1 | .500 | 1 | .500 | 2 | 25 | 11 | .440 | 32 | 32 | 14 |
| LaTroy Hawkins |   | mr | 33 | 4 | 0 | .000 | 4 | 1.000 | 16 | 12 | 2 | .167 | 60 | 60 | 12 |
| Aaron Heilman | WIZ | mr | 27 | 5 | 0 | .000 | 5 | 1.000 | 27 | 14 | 7 | .500 | 74 | 74 | 14 |
| Rick Helling |   | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 2 | .200 | 20 | 18 | 4 |
| Ben Hendrickson |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 4 | 1 | 0 |
| Mark Hendrickson* | MUL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 31 | 6 | 0 |
| Sean Henn* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 3 | 0 |
| Brad Hennessey |   | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 3 | 17 | 7 | .412 | 34 | 22 | 9 |
| Clay Hensley | WIZ | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 1 | 1 | 1.000 | 37 | 8 | 2 |
| Matt Herges |   | mr | 36 | 4 | 0 | .000 | 4 | 1.000 | 9 | 54 | 22 | .407 | 66 | 66 | 21 |
| Dustin Hermanson |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 6 | 6 | 3 |
| Felix Hernandez | ROK | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Livan Hernandez |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Orlando Hernandez | Pal | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Roberto Hernandez |   | mr | 41 | 5 | 2 | .400 | 3 | .600 | 12 | 22 | 7 | .318 | 68 | 68 | 19 |
| Runelvys Hernandez |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| Rich Hill* | BT | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 1 | 1 |
| Shawn Hill |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Jason Hirsh |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| James Hoey |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 4 | 4 | 2 | .500 | 12 | 12 | 2 |
| Trevor Hoffman | Pal | cl | 38 | 51 | 46 | .902 | 5 | .098 | 0 | 1 | 0 | .000 | 65 | 65 | 50 |
| Mike Holtz* |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 3 | 3 | 1 |
| J.P. Howell* | MID | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Bob Howry | COP | mr | 32 | 9 | 5 | .556 | 4 | .444 | 21 | 33 | 9 | .273 | 84 | 84 | 26 |
| Jon Huber |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 6 | 12 | 3 | .250 | 16 | 16 | 4 |
| Luke Hudson | MID | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 1 | 11 | 4 | .364 | 26 | 11 | 1 |
| Tim Hudson | GEO | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 |
| Travis Hughes |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 8 | 8 | 2 |
| Philip Humber |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Jason Isringhausen | Pal | cl | 33 | 43 | 33 | .767 | 10 | .233 | 0 | 25 | 10 | .400 | 59 | 59 | 51 |
| Edwin Jackson |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 4 | .500 | 23 | 22 | 7 |
| Zach Jackson* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 1 | 1 |
| Chuck James* | Pal | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 25 | 7 | 0 |
| Casey Janssen | OTR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 2 | 1 |
| Kevin Jarvis |   | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 9 | 5 | 2 |
| Bobby Jenks | OTR | cl | 25 | 45 | 41 | .911 | 4 | .089 | 0 | 30 | 5 | .167 | 67 | 67 | 58 |
| Jason Jennings | CCL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Cesar Jimenez* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 4 | 3 | 1 |
| Ubaldo Jimenez |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 0 |
| Jason Johnson |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 4 | 0 |
| Jim Johnson |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Josh Johnson | LON | sp | 22 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 2 | 1.000 | 31 | 7 | 1 |
| Randy Johnson* | ROK | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Tyler Johnson* |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 12 | 46 | 15 | .326 | 56 | 56 | 12 |
| Greg Jones |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 5 | 5 | 2 |
| Todd Jones | MUL | cl | 38 | 43 | 37 | .860 | 6 | .140 | 0 | 5 | 4 | .800 | 62 | 62 | 56 |
| Jorge Julio |   | cl | 27 | 20 | 16 | .800 | 4 | .200 | 1 | 3 | 1 | .333 | 62 | 62 | 44 |
| Steve Karsay |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 2 | .500 | 9 | 9 | 5 |
| Jeff Karstens | BON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 2 |
| Scott Kazmir* | GEO | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Randy Keisler* |   | mr | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 5 | .500 | 11 | 11 | 2 |
| Joe Kennedy* |   | mr | 27 | 3 | 1 | .333 | 2 | .667 | 14 | 21 | 2 | .095 | 39 | 39 | 8 |
| Logan Kensing |   | mr | 23 | 7 | 1 | .143 | 6 | .857 | 14 | 13 | 2 | .154 | 37 | 37 | 10 |
| Bobby Keppel |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 8 | 2 | 0 |
| Byung-Hyun Kim |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Sun-Woo Kim |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 8 | 7 | 1 |
| Ray King* |   | mr | 32 | 2 | 1 | .500 | 1 | .500 | 16 | 56 | 20 | .357 | 67 | 67 | 7 |
| Josh Kinney |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 3 | 6 | 0 | .000 | 21 | 21 | 4 |
| Steve Kline* |   | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 18 | 52 | 16 | .308 | 72 | 72 | 17 |
| Dan Kolb |   | mr | 31 | 3 | 1 | .333 | 2 | .667 | 6 | 26 | 12 | .462 | 53 | 53 | 18 |
| Shane Komine |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Mike Koplove |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 2 | 2 | 0 |
| John Koronka* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 |
| Hong-Chih Kuo* | Pal | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 5 | .417 | 28 | 23 | 6 |
| John Lackey | COP | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Juan Lara* |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 11 | 2 | .182 | 9 | 9 | 1 |
| Brandon League | CRH | mr | 23 | 4 | 1 | .250 | 3 | .750 | 12 | 9 | 4 | .444 | 33 | 33 | 8 |
| Wilfredo Ledezma* |   | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 16 | 7 | .438 | 24 | 17 | 2 |
| Cliff Lee* | MID | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Justin Lehr |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 11 | 5 | .455 | 16 | 16 | 4 |
| Anthony Lerew |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Jon Lester* | EDG | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Colby Lewis |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 3 | .750 | 2 | 2 | 1 |
| Brad Lidge | Pal | cl | 29 | 38 | 32 | .842 | 6 | .158 | 6 | 16 | 5 | .313 | 78 | 78 | 52 |
| Cory Lidle |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 0 |
| Jon Lieber |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Ted Lilly* | OTR | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Jose Lima |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Scott Linebrink |   | mr | 29 | 11 | 2 | .182 | 9 | .818 | 36 | 8 | 2 | .250 | 73 | 73 | 11 |
| Francisco Liriano* | ROK | sp | 22 | 1 | 1 | 1.000 | 0 | .000 | 1 | 6 | 2 | .333 | 28 | 12 | 2 |
| Wes Littleton |   | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 8 | 18 | 3 | .167 | 33 | 33 | 6 |
| Bobby Livingston* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Esteban Loaiza |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Kameron Loe |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 |
| Adam Loewen* | MID | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 2 | .667 | 22 | 3 | 1 |
| Boone Logan* |   | mr | 21 | 2 | 1 | .500 | 1 | .500 | 2 | 17 | 10 | .588 | 21 | 21 | 4 |
| Kyle Lohse | MID | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 34 | 15 | 6 |
| Braden Looper | MAD | mr | 31 | 2 | 0 | .000 | 2 | 1.000 | 15 | 25 | 11 | .440 | 69 | 69 | 28 |
| Javier Lopez* |   | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 6 | 32 | 11 | .344 | 27 | 27 | 8 |
| Rodrigo Lopez |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 36 | 7 | 2 |
| Derek Lowe | BON | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 1 | 1 |
| Mark Lowe |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 6 | 16 | 4 | .250 | 15 | 15 | 3 |
| Noah Lowry* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 |
| Ruddy Lugo | GEO | mr | 26 | 0 | 0 | .000 | 0 | .000 | 8 | 30 | 15 | .500 | 64 | 64 | 24 |
| Brandon Lyon | Pal | mr | 26 | 7 | 0 | .000 | 7 | 1.000 | 23 | 21 | 7 | .333 | 68 | 68 | 22 |
| Chris Mabeus |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Mike MacDougal |   | mr | 29 | 2 | 1 | .500 | 1 | .500 | 11 | 20 | 5 | .250 | 29 | 29 | 7 |
| Greg Maddux | Pal | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Ryan Madson | CCL | mr | 25 | 4 | 2 | .500 | 2 | .500 | 6 | 11 | 4 | .364 | 50 | 33 | 8 |
| Ron Mahay* |   | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 10 | 38 | 9 | .237 | 62 | 62 | 14 |
| Paul Maholm* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| John Maine | BT | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 1 |
| Gary Majewski |   | mr | 26 | 7 | 0 | .000 | 7 | 1.000 | 8 | 29 | 9 | .310 | 65 | 65 | 21 |
| Julio Manon |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 2 | 14 | 5 | .357 | 22 | 22 | 8 |
| Shaun Marcum | COP | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 21 | 7 | 3 |
| Carlos Marmol | WIZ | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 6 | 1 |
| Mike Maroth* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 13 | 4 | 2 |
| Jason Marquis |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Sean Marshall* | LON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 |
| Damaso Marte* | WIZ | mr | 31 | 4 | 0 | .000 | 4 | 1.000 | 13 | 40 | 11 | .275 | 75 | 75 | 15 |
| Tom Martin* |   | mr | 36 | 1 | 0 | .000 | 1 | 1.000 | 11 | 54 | 18 | .333 | 68 | 68 | 9 |
| Carlos Martinez |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 5 | 5 | 1 | .200 | 12 | 12 | 4 |
| Pedro Martinez | WIZ | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 |
| Nick Masset |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 8 | 7 |
| Tom Mastny |   | cl | 25 | 7 | 5 | .714 | 2 | .286 | 0 | 6 | 0 | .000 | 15 | 15 | 12 |
| Juan Mateo |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 1 | 0 |
| Julio Mateo |   | mr | 28 | 3 | 0 | .000 | 3 | 1.000 | 7 | 43 | 18 | .419 | 48 | 48 | 13 |
| Scott Mathieson |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 9 | 1 | 0 |
| Joe Mays |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 13 | 3 | 0 |
| Macay McBride* |   | mr | 23 | 2 | 1 | .500 | 1 | .500 | 10 | 49 | 10 | .204 | 71 | 71 | 13 |
| Brandon McCarthy |   | mr | 22 | 1 | 0 | .000 | 1 | 1.000 | 12 | 36 | 14 | .389 | 53 | 51 | 13 |
| Seth McClung |   | mr | 25 | 7 | 6 | .857 | 1 | .143 | 0 | 9 | 3 | .333 | 39 | 24 | 20 |
| Dustin McGowan |   | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 1 | 9 | 5 | .556 | 16 | 13 | 3 |
| Marty McLeary |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 0 | .000 | 5 | 3 | 1 |
| Brian Meadows |   | mr | 30 | 10 | 8 | .800 | 2 | .200 | 4 | 28 | 17 | .607 | 53 | 53 | 27 |
| Gil Meche | CRH | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Brandon Medders |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 11 | 22 | 8 | .364 | 60 | 60 | 13 |
| Kent Mercker* |   | mr | 38 | 3 | 1 | .333 | 2 | .667 | 6 | 20 | 6 | .300 | 37 | 37 | 7 |
| Cla Meredith | WIZ | mr | 23 | 2 | 0 | .000 | 2 | 1.000 | 16 | 38 | 9 | .237 | 45 | 45 | 11 |
| Jose Mesa |   | mr | 40 | 8 | 1 | .125 | 7 | .875 | 19 | 35 | 16 | .457 | 79 | 79 | 26 |
| Randy Messenger |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 9 | 25 | 9 | .360 | 59 | 59 | 10 |
| Dan Miceli |   | mr | 35 | 7 | 4 | .571 | 3 | .429 | 6 | 22 | 5 | .227 | 33 | 33 | 14 |
| Chris Michalak* |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 0 |
| Andrew Miller* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 8 | 8 | 3 |
| Matt Miller |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 5 | .556 | 14 | 14 | 3 |
| Trever Miller* | CCL | mr | 33 | 3 | 1 | .333 | 2 | .667 | 12 | 40 | 7 | .175 | 70 | 70 | 14 |
| Wade Miller |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Kevin Millwood | CCL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Eric Milton* |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 |
| Zach Miner |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 4 | .500 | 27 | 11 | 4 |
| Patrick Misch* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Sergio Mitre |   | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 0 | 0 | .000 | 15 | 8 | 3 |
| Brian Moehler |   | sp | 34 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 3 | .500 | 29 | 8 | 2 |
| Agustin Montero |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 9 | 4 | .444 | 11 | 11 | 6 |
| Juan Morillo |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Matt Morris | CCL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Dustin Moseley |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 3 | 1 | 1 |
| Guillermo Mota |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 9 | 17 | 7 | .412 | 52 | 52 | 17 |
| Jamie Moyer* |   | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Peter Moylan |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 15 | 15 | 5 |
| Edward Mujica |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 7 | .583 | 10 | 10 | 2 |
| Mark Mulder* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| Terry Mulholland* |   | mr | 43 | 1 | 0 | .000 | 1 | 1.000 | 1 | 1 | 1 | 1.000 | 5 | 5 | 0 |
| Scott Munter |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 5 | 22 | 10 | .455 | 27 | 27 | 11 |
| Mike Mussina | GEO | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Brett Myers | Pal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Mike Myers* |   | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 18 | 57 | 13 | .228 | 62 | 62 | 6 |
| Clint Nageotte |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 |
| Chris Narveson* |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 4 | 1 |
| Joe Nathan | WIZ | cl | 31 | 38 | 36 | .947 | 2 | .053 | 0 | 6 | 2 | .333 | 64 | 64 | 61 |
| Jeff Nelson |   | mr | 39 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 1 | .333 | 6 | 6 | 3 |
| Joe Nelson |   | mr | 31 | 10 | 9 | .900 | 1 | .100 | 5 | 15 | 4 | .267 | 43 | 43 | 20 |
| Pat Neshek |   | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 10 | 29 | 3 | .103 | 32 | 32 | 3 |
| Fernando Nieve |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 16 | 5 | .313 | 40 | 29 | 11 |
| Dustin Nippert |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Ricky Nolasco |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 3 | 11 | 5 | .455 | 35 | 13 | 0 |
| Roberto Novoa |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 4 | 38 | 9 | .237 | 66 | 66 | 10 |
| Leo Nunez |   | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 7 | 7 | 5 |
| Mike O'Connor* | BT | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 21 | 1 | 0 |
| Eric O'Flaherty* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 3 | .250 | 15 | 15 | 5 |
| Ryan O'Malley* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 |
| Tomo Ohka |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 |
| Will Ohman* | MAD | mr | 28 | 0 | 0 | .000 | 0 | .000 | 10 | 41 | 8 | .195 | 78 | 78 | 14 |
| Darren Oliver* |   | mr | 35 | 2 | 0 | .000 | 2 | 1.000 | 4 | 18 | 7 | .389 | 45 | 45 | 10 |
| Scott Olsen* | TON | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Ramon Ortiz |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Russ Ortiz |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 5 | .500 | 26 | 15 | 5 |
| Chad Orvella |   | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 1 | 18 | 13 | .722 | 22 | 22 | 5 |
| Franquelis Osoria |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 12 | 12 | 1 |
| Roy Oswalt | BT | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 1 | 1 |
| Akinori Otsuka | MAD | cl | 34 | 36 | 32 | .889 | 4 | .111 | 7 | 6 | 2 | .333 | 63 | 63 | 48 |
| Henry Owens |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 |
| Vicente Padilla |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Jonathan Papelbon | BON | cl | 25 | 41 | 35 | .854 | 6 | .146 | 1 | 24 | 4 | .167 | 59 | 59 | 49 |
| Chan Ho Park |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 24 | 3 | 0 |
| Chad Paronto | CCL | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 8 | 52 | 14 | .269 | 65 | 65 | 11 |
| John Patterson |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| David Pauley |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 |
| Jake Peavy | MUL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Mike Pelfrey |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Tony Pena |   | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 6 | 2 | .333 | 25 | 25 | 6 |
| Hayden Penn |   | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 |
| Brad Penny | LON | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 34 | 1 | 0 |
| Joel Peralta |   | mr | 30 | 3 | 1 | .333 | 2 | .667 | 17 | 54 | 19 | .352 | 64 | 64 | 21 |
| Beltran Perez |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 8 | 5 | 1 |
| Juan Perez* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 7 | 7 | 0 |
| Odalis Perez* |   | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 1 | .333 | 32 | 12 | 6 |
| Oliver Perez* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 |
| Rafael Perez* |   | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 10 | 2 | .200 | 18 | 18 | 5 |
| Glen Perkins* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 4 | 4 | 1 |
| Yusmeiro Petit |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 14 | 5 |
| Andy Pettitte* |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 1 | 1 |
| Joel Pineiro |   | sp | 27 | 2 | 1 | .500 | 1 | .500 | 4 | 11 | 5 | .455 | 40 | 15 | 6 |
| Renyel Pinto* |   | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 3 | 13 | 3 | .231 | 27 | 27 | 7 |
| Cliff Politte |   | mr | 32 | 2 | 0 | .000 | 2 | 1.000 | 4 | 11 | 3 | .273 | 30 | 30 | 13 |
| Sidney Ponson |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 19 | 3 | 1 |
| Mark Prior |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Scott Proctor | EDG | mr | 29 | 8 | 1 | .125 | 7 | .875 | 27 | 64 | 17 | .266 | 83 | 83 | 12 |
| J.J. Putz | MID | cl | 29 | 43 | 36 | .837 | 7 | .163 | 5 | 40 | 7 | .175 | 72 | 72 | 57 |
| Chad Qualls | LON | mr | 27 | 6 | 0 | .000 | 6 | 1.000 | 23 | 54 | 15 | .278 | 81 | 81 | 13 |
| Brad Radke | BON | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Elizardo Ramirez |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 2 | 1 |
| Horacio Ramirez* | MUL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Ramon Ramirez | LON | mr | 24 | 3 | 0 | .000 | 3 | 1.000 | 11 | 35 | 14 | .400 | 61 | 61 | 14 |
| Santiago Ramirez |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 3 | .500 | 4 | 4 | 1 |
| Darrell Rasner |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 4 | .667 | 6 | 3 | 1 |
| Jon Rauch |   | mr | 27 | 6 | 2 | .333 | 4 | .667 | 18 | 34 | 8 | .235 | 85 | 85 | 19 |
| Chris Ray | MID | cl | 24 | 38 | 33 | .868 | 5 | .132 | 1 | 19 | 7 | .368 | 61 | 61 | 56 |
| Ken Ray |   | mr | 31 | 8 | 5 | .625 | 3 | .375 | 7 | 19 | 9 | .474 | 69 | 69 | 29 |
| Britt Reames |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 6 | 6 | 5 |
| Mark Redman* |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 |
| Chris Reitsma |   | cl | 28 | 12 | 8 | .667 | 4 | .333 | 3 | 9 | 2 | .222 | 27 | 27 | 16 |
| Mike Remlinger* |   | mr | 40 | 5 | 2 | .400 | 3 | .600 | 2 | 31 | 10 | .323 | 36 | 36 | 7 |
| Chris Resop |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 2 | 3 | 0 | .000 | 22 | 22 | 10 |
| Anthony Reyes |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| Dennys Reyes* | BON | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 17 | 45 | 6 | .133 | 66 | 66 | 8 |
| John Rheinecker* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 1 | .167 | 21 | 8 | 2 |
| Arthur Rhodes* |   | mr | 36 | 7 | 4 | .571 | 3 | .429 | 23 | 7 | 1 | .143 | 55 | 55 | 10 |
| Juan Rincon | COP | mr | 27 | 3 | 1 | .333 | 2 | .667 | 26 | 29 | 9 | .310 | 75 | 75 | 22 |
| Ricardo Rincon* |   | mr | 36 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 1 | .167 | 5 | 5 | 1 |
| Royce Ring* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 1 | .125 | 11 | 11 | 2 |
| David Riske | CRH | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 2 | 29 | 14 | .483 | 41 | 41 | 12 |
| Mariano Rivera | ROK | cl | 36 | 37 | 34 | .919 | 3 | .081 | 0 | 18 | 7 | .389 | 63 | 63 | 59 |
| Saul Rivera |   | mr | 28 | 3 | 1 | .333 | 2 | .667 | 9 | 29 | 9 | .310 | 54 | 54 | 16 |
| Sendy Rleal |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 3 | 20 | 10 | .500 | 42 | 42 | 14 |
| Nate Robertson* |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Fernando Rodney | OTR | mr | 29 | 11 | 7 | .636 | 4 | .364 | 18 | 23 | 10 | .435 | 63 | 63 | 30 |
| Eddy Rodriguez |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 9 | 9 | 6 |
| Felix Rodriguez |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 3 | 8 | 3 | .375 | 31 | 31 | 9 |
| Francisco Rodriguez | BON | cl | 24 | 51 | 47 | .922 | 4 | .078 | 0 | 20 | 8 | .400 | 69 | 69 | 58 |
| Wandy Rodriguez* |   | sp | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 0 | .000 | 30 | 6 | 1 |
| Brian Rogers |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 10 | 10 | 4 |
| Kenny Rogers* | EDG | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 1 |
| Davis Romero* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 0 | .000 | 7 | 7 | 1 |
| J.C. Romero* |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 7 | 44 | 13 | .295 | 65 | 65 | 16 |
| Matt Roney |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 2 |
| Francisco Rosario |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 4 | 0 | .000 | 17 | 16 | 4 |
| Josh Rupe |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 9 | 3 | .333 | 16 | 16 | 3 |
| Glendon Rusch* |   | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 2 | .143 | 25 | 16 | 5 |
| B.J. Ryan* | MID | cl | 30 | 42 | 38 | .905 | 4 | .095 | 1 | 29 | 1 | .034 | 65 | 65 | 57 |
| Jae Kuk Ryu |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 10 | 9 | 4 |
| Kirk Saarloos |   | mr | 27 | 3 | 2 | .667 | 1 | .333 | 0 | 21 | 6 | .286 | 35 | 19 | 7 |
| C.C. Sabathia* | CRH | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 |
| Billy Sadler |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 5 | 5 | 2 |
| Takashi Saito | Pal | cl | 36 | 26 | 24 | .923 | 2 | .077 | 7 | 27 | 9 | .333 | 72 | 72 | 48 |
| Juan Salas |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 2 | 1 | .500 | 8 | 8 | 2 |
| Chris Sampson |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 12 | 9 | 0 |
| Brian Sanches |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 3 | .375 | 18 | 18 | 5 |
| Anibal Sanchez | MAD | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 18 | 1 | 0 |
| Duaner Sanchez | MAD | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 14 | 10 | 2 | .200 | 49 | 49 | 15 |
| Jonathan Sanchez* |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 5 | 14 | 8 | .571 | 27 | 23 | 4 |
| Ervin Santana | BON | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Johan Santana* | ROK | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Julio Santana |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 7 | 7 | 2 |
| Victor Santos |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 6 | .600 | 25 | 6 | 3 |
| Dennis Sarfate |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 8 | 8 | 5 |
| Scott Sauerbeck* |   | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 5 | 28 | 7 | .250 | 46 | 46 | 11 |
| Joe Saunders* | MID | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Curt Schilling | CRH | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Jason Schmidt | WIZ | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Scott Schoeneweis* |   | mr | 32 | 6 | 4 | .667 | 2 | .333 | 19 | 45 | 10 | .222 | 71 | 71 | 16 |
| Chris Schroder |   | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 11 | 5 | .455 | 21 | 21 | 3 |
| Rudy Seanez |   | mr | 37 | 2 | 0 | .000 | 2 | 1.000 | 3 | 18 | 11 | .611 | 49 | 49 | 22 |
| Bobby Seay* |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 14 | 14 | 6 |
| Aaron Sele |   | sp | 36 | 2 | 0 | .000 | 2 | 1.000 | 0 | 9 | 3 | .333 | 28 | 13 | 4 |
| Jae Seo |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 0 | .000 | 36 | 10 | 5 |
| Brian Shackelford* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 19 | 4 | .211 | 26 | 26 | 9 |
| Josh Sharpless |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 3 | .273 | 14 | 14 | 3 |
| Ben Sheets | TON | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 |
| George Sherrill* | ROK | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 17 | 59 | 14 | .237 | 72 | 72 | 6 |
| James Shields | BON | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 |
| Scot Shields | ROK | mr | 30 | 8 | 2 | .250 | 6 | .750 | 31 | 32 | 10 | .313 | 74 | 74 | 13 |
| Jason Shiell |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 0 |
| Brian Shouse* | OTR | mr | 37 | 5 | 2 | .400 | 3 | .600 | 15 | 60 | 16 | .267 | 65 | 65 | 10 |
| Brian Sikorski |   | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 2 | 15 | 6 | .400 | 30 | 30 | 10 |
| Carlos Silva |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 0 | 0 | .000 | 36 | 5 | 2 |
| Allan Simpson |   | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 |
| Andrew Sisco* |   | mr | 23 | 6 | 1 | .167 | 5 | .833 | 5 | 63 | 27 | .429 | 65 | 65 | 16 |
| Doug Slaten* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 0 | .000 | 9 | 9 | 0 |
| Brian Slocum |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 8 | 6 | 1 |
| Aaron Small |   | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 11 | 8 | 2 |
| Matt Smith* |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 6 | 12 | 2 | .167 | 26 | 26 | 9 |
| Mike Smith |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Travis Smith |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| John Smoltz | WIZ | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 |
| Ian Snell |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Kyle Snyder |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 17 | 6 | 3 |
| Alay Soler |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Rafael Soriano | GEO | mr | 26 | 6 | 2 | .333 | 4 | .667 | 18 | 39 | 12 | .308 | 53 | 53 | 14 |
| Jorge Sosa |   | mr | 29 | 7 | 4 | .571 | 3 | .429 | 0 | 17 | 3 | .176 | 45 | 32 | 12 |
| Jeremy Sowers* | EDG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Justin Speier | MID | mr | 32 | 3 | 0 | .000 | 3 | 1.000 | 25 | 36 | 17 | .472 | 58 | 58 | 8 |
| Russ Springer | WIZ | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 9 | 40 | 11 | .275 | 72 | 72 | 17 |
| Chris Spurling |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 14 | 7 | .500 | 16 | 16 | 3 |
| Jason Standridge |   | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 0 | .000 | 21 | 21 | 2 |
| Mike Stanton* |   | mr | 39 | 14 | 8 | .571 | 6 | .429 | 15 | 59 | 12 | .203 | 82 | 82 | 22 |
| Tim Stauffer | MAD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 |
| Steve Stemle |   | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 5 | 5 | 1 |
| Phil Stockman |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 1 |
| Brian Stokes |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 5 | 1 | 0 |
| Huston Street | GEO | cl | 22 | 48 | 37 | .771 | 11 | .229 | 1 | 30 | 7 | .233 | 69 | 69 | 55 |
| Eric Stults* |   | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 4 | 2 |
| Tanyon Sturtze |   | mr | 35 | 0 | 0 | .000 | 0 | .000 | 3 | 15 | 3 | .200 | 18 | 18 | 2 |
| Jeff Suppan |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Brian Sweeney | MUL | mr | 32 | 3 | 2 | .667 | 1 | .333 | 0 | 17 | 8 | .471 | 37 | 37 | 15 |
| Jon Switzer* |   | mr | 26 | 3 | 0 | .000 | 3 | 1.000 | 5 | 28 | 6 | .214 | 40 | 40 | 6 |
| Brian Tallet* |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 5 | 44 | 13 | .295 | 44 | 43 | 8 |
| Taylor Tankersley* | MAD | mr | 23 | 7 | 3 | .429 | 4 | .571 | 22 | 39 | 13 | .333 | 49 | 49 | 10 |
| Jack Taschner* |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 4 | 20 | 10 | .500 | 24 | 24 | 6 |
| Jordan Tata |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 8 | 8 | 2 |
| Ty Taubenheim |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 12 | 5 | 1 |
| Julian Tavarez |   | mr | 33 | 3 | 1 | .333 | 2 | .667 | 2 | 36 | 18 | .500 | 58 | 52 | 11 |
| Robinson Tejeda |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 |
| Brad Thompson |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 3 | 26 | 7 | .269 | 43 | 42 | 16 |
| Mike Thompson |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 3 | 2 |
| John Thomson |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 2 | 2 | 1 | .500 | 18 | 3 | 1 |
| Matt Thornton* | CRH | mr | 29 | 5 | 2 | .400 | 3 | .600 | 18 | 48 | 13 | .271 | 63 | 63 | 20 |
| Mike Timlin | OTR | mr | 40 | 17 | 9 | .529 | 8 | .471 | 21 | 25 | 9 | .360 | 68 | 68 | 22 |
| Brett Tomko |   | mr | 33 | 3 | 0 | .000 | 3 | 1.000 | 5 | 6 | 3 | .500 | 44 | 29 | 2 |
| Salomon Torres | CCL | mr | 34 | 15 | 12 | .800 | 3 | .200 | 20 | 55 | 14 | .255 | 94 | 94 | 24 |
| Josh Towers |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 15 | 3 | 1 |
| Billy Traber* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 3 | 0 | .000 | 15 | 7 | 0 |
| Sean Tracey |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 7 | 7 | 5 |
| Steve Trachsel |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Derrick Turnbow |   | cl | 28 | 32 | 24 | .750 | 8 | .250 | 4 | 14 | 1 | .071 | 64 | 64 | 49 |
| Jose Valverde | WIZ | cl | 26 | 22 | 18 | .818 | 4 | .182 | 1 | 7 | 1 | .143 | 44 | 44 | 35 |
| Jermaine Van Buren |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 3 | 7 | 2 | .286 | 10 | 10 | 0 |
| Claudio Vargas |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 1 |
| Jason Vargas* |   | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 2 | .333 | 12 | 7 | 3 |
| Javier Vazquez | Pal | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 33 | 1 | 0 |
| Mike Venafro* |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 3 | .429 | 7 | 7 | 0 |
| Jose Veras |   | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 6 | 2 | .333 | 12 | 12 | 4 |
| Justin Verlander | COP | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 |
| Carlos Villanueva | TON | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 10 | 4 | 2 |
| Oscar Villarreal |   | mr | 24 | 4 | 0 | .000 | 4 | 1.000 | 4 | 26 | 11 | .423 | 58 | 54 | 11 |
| Ron Villone* |   | mr | 36 | 3 | 0 | .000 | 3 | 1.000 | 7 | 51 | 12 | .235 | 70 | 70 | 19 |
| Luis Vizcaino | LON | mr | 31 | 2 | 0 | .000 | 2 | 1.000 | 25 | 18 | 5 | .278 | 70 | 70 | 15 |
| Ryan Vogelsong |   | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 13 | 5 | .385 | 20 | 20 | 7 |
| Edinson Volquez |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 |
| Doug Waechter |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 1 | 0 |
| Billy Wagner* | BT | cl | 34 | 45 | 40 | .889 | 5 | .111 | 0 | 5 | 1 | .200 | 70 | 70 | 59 |
| Ryan Wagner |   | mr | 23 | 2 | 0 | .000 | 2 | 1.000 | 3 | 15 | 3 | .200 | 26 | 26 | 5 |
| Adam Wainwright | MAD | mr | 24 | 5 | 3 | .600 | 2 | .400 | 17 | 15 | 4 | .267 | 61 | 61 | 10 |
| Tim Wakefield | OTR | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 |
| Jamie Walker* | OTR | mr | 34 | 0 | 0 | .000 | 0 | .000 | 11 | 32 | 8 | .250 | 56 | 56 | 14 |
| Pete Walker |   | mr | 37 | 1 | 1 | 1.000 | 0 | .000 | 3 | 5 | 3 | .600 | 23 | 23 | 9 |
| Tyler Walker |   | cl | 30 | 14 | 10 | .714 | 4 | .286 | 1 | 16 | 1 | .063 | 26 | 26 | 17 |
| Les Walrond* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 10 | 8 | 0 |
| Chien-Ming Wang | COP | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 1 |
| John Wasdin |   | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 4 | 3 |
| Jarrod Washburn* |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| David Weathers | TON | mr | 36 | 19 | 12 | .632 | 7 | .368 | 9 | 19 | 5 | .263 | 67 | 67 | 32 |
| Jeff Weaver |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Jered Weaver | OTR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 |
| Brandon Webb | TON | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Todd Wellemeyer |   | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 5 | 34 | 14 | .412 | 46 | 46 | 10 |
| David Wells* | EDG | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 |
| Kip Wells |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 |
| Jake Westbrook | MID | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 |
| Dan Wheeler | Pal | mr | 28 | 12 | 9 | .750 | 3 | .250 | 24 | 32 | 13 | .406 | 75 | 75 | 25 |
| Rick White |   | mr | 37 | 2 | 1 | .500 | 1 | .500 | 8 | 25 | 8 | .320 | 64 | 64 | 20 |
| Bob Wickman | COP | cl | 37 | 37 | 33 | .892 | 4 | .108 | 0 | 3 | 2 | .667 | 57 | 57 | 55 |
| Dave Williams* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 1 | 1 |
| Jerome Williams |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 3 | 1 |
| Todd Williams |   | mr | 35 | 5 | 1 | .200 | 4 | .800 | 13 | 39 | 17 | .436 | 62 | 62 | 5 |
| Woody Williams | MUL | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 1 | 0 |
| Scott Williamson |   | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 3 | 24 | 6 | .250 | 42 | 42 | 10 |
| Dontrelle Willis* | MAD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Brian Wilson |   | mr | 24 | 2 | 1 | .500 | 1 | .500 | 4 | 17 | 2 | .118 | 31 | 31 | 9 |
| C.J. Wilson* | ROK | mr | 25 | 2 | 1 | .500 | 1 | .500 | 8 | 27 | 9 | .333 | 44 | 44 | 12 |
| Kris Wilson |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 5 | 4 | 1 |
| Jason Windsor |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 |
| Joe Winkelsas |   | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 11 | 7 | .636 | 7 | 7 | 1 |
| Matt Wise |   | mr | 30 | 4 | 0 | .000 | 4 | 1.000 | 14 | 10 | 3 | .300 | 40 | 40 | 9 |
| Jay Witasick |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 2 | 10 | 4 | .400 | 20 | 20 | 8 |
| Randy Wolf* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 |
| Kerry Wood | MUL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 |
| Mike Wood |   | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 15 | 5 | .333 | 23 | 16 | 2 |
| Jake Woods* |   | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 29 | 15 | .517 | 37 | 29 | 10 |
| Tim Worrell |   | cl | 38 | 8 | 6 | .750 | 2 | .250 | 1 | 14 | 8 | .571 | 23 | 23 | 12 |
| Jamey Wright |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 9 | .900 | 34 | 13 | 2 |
| Jaret Wright |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 30 | 3 | 0 |
| Michael Wuertz | BT | mr | 27 | 3 | 0 | .000 | 3 | 1.000 | 7 | 37 | 16 | .432 | 41 | 41 | 4 |
| Esteban Yan |   | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 26 | 10 | .385 | 27 | 27 | 12 |
| Tyler Yates | TON | mr | 28 | 6 | 1 | .167 | 5 | .833 | 12 | 30 | 8 | .267 | 56 | 56 | 11 |
| Shane Youman* |   | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 5 | 2 | 0 |
| Chris Young | COP | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 |
| Carlos Zambrano | CCL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 |
| Victor Zambrano |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 |
| Barry Zito* | EDG | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 |
| Joel Zumaya | ROK | mr | 21 | 6 | 1 | .167 | 5 | .833 | 31 | 40 | 14 | .350 | 62 | 62 | 12 |