| Transactions | ||||||
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/28/2005 | ROK | Bartlett | Demoted to reserve roster | Before | ||
| 4/28/2005 | ROK | Williams | Demoted to reserve roster | Before | ||
| 5/5/2005 | CRH | Johnson | Demoted to reserve roster | Before | ||
| 5/5/2005 | ROK | Romero | Demoted to reserve roster | Before | ||
| 5/12/2005 | WIZ | Capuano | Demoted to reserve roster | Before | ||
| 5/19/2005 | TON | Encarnacion | Demoted to reserve roster | Before | ||
| 5/19/2005 | TON | Schneider | Demoted to reserve roster | Before | ||
| 5/26/2005 | CRH | Boone | Demoted to reserve roster | Before | ||
| 5/26/2005 | CRH | Kennedy | Demoted to reserve roster | Before | ||
| 5/26/2005 | Pal | Lo Duca | Demoted to reserve roster | Before | ||
| 6/1/2005 | BT | Burnitz | Traded away | WIZ | After | |
| 6/1/2005 | BT | Carroll | Acquired via trade | WIZ | After | |
| 6/1/2005 | WIZ | Burnitz | Acquired via trade | BT | After | |
| 6/1/2005 | WIZ | Carroll | Traded away | BT | After | |
| 6/2/2005 | WIZ | Wilson | Demoted to reserve roster | Before | ||
| 6/15/2005 | COP | Byrnes | Traded away | MAD | After | |
| 6/15/2005 | COP | Hatteberg | Traded away | MAD | After | |
| 6/15/2005 | COP | Patterson | Acquired via trade | MAD | After | |
| 6/15/2005 | COP | Sanders | Acquired via trade | MAD | After | |
| 6/15/2005 | MAD | Byrnes | Acquired via trade | COP | After | |
| 6/15/2005 | MAD | Hatteberg | Acquired via trade | COP | After | |
| 6/15/2005 | MAD | Patterson | Traded away | COP | After | |
| 6/15/2005 | MAD | Sanders | Traded away | COP | After | |
| 6/16/2005 | OTR | Rios | Demoted to reserve roster | Before | ||
| 6/23/2005 | BT | Cabrera | Demoted to reserve roster | Before | ||
| 6/23/2005 | BT | Cabrera | Promoted to active roster | Before | ||
| 6/23/2005 | COP | Cabrera | Demoted to reserve roster | Before | ||
| 6/23/2005 | COP | Gathright | Demoted to reserve roster | Before | ||
| 7/6/2005 | GEO | Clark | Traded away | Pal | After | |
| 7/6/2005 | GEO | DeRosa | Acquired via trade | Pal | After | |
| 7/6/2005 | Pal | Clark | Acquired via trade | GEO | After | |
| 7/6/2005 | Pal | DeRosa | Traded away | GEO | After | |
| 7/7/2005 | GEO | DeJesus | Promoted to active roster | Before | ||
| 7/7/2005 | Pal | Conine | Demoted to reserve roster | Before | ||
| 7/20/2005 | CRH | Gibbons | Acquired via trade | MID | After | |
| 7/20/2005 | CRH | Ryan | Traded away | MID | After | |
| 7/20/2005 | MID | Gibbons | Traded away | CRH | After | |
| 7/20/2005 | MID | Ryan | Acquired via trade | CRH | After | |
| 8/3/2005 | MAD | Cook | Acquired via trade | Pal | After | |
| 8/3/2005 | MAD | Lo Duca | Acquired via trade | Pal | After | |
| 8/3/2005 | MAD | Maddux | Traded away | Pal | After | |
| 8/3/2005 | Pal | Cook | Traded away | MAD | After | |
| 8/3/2005 | Pal | Lo Duca | Traded away | MAD | After | |
| 8/3/2005 | Pal | Maddux | Acquired via trade | MAD | After | |
| 8/4/2005 | MAD | Lo Duca | Promoted to active roster | Before | ||
| 8/10/2005 | LON | Bartlett | Acquired via trade | ROK | After | |
| 8/10/2005 | LON | Walker | Traded away | ROK | After | |
| 8/10/2005 | ROK | Bartlett | Traded away | LON | After | |
| 8/10/2005 | ROK | Walker | Acquired via trade | LON | After | |
| 8/11/2005 | LON | Vidro | Promoted to active roster | Before | ||
| 10/6/2005 | COP | Young,C | Demoted to reserve roster | Before | ||
| 10/6/2005 | ROK | Baez | Demoted to reserve roster | Before | ||
| 10/6/2005 | ROK | Williams | Demoted to reserve roster | Before | ||
| 10/12/2005 | Pal | DeJean | Demoted to reserve roster | Before | ||
| 1/19/2026 | MID | Johnson | Traded away | ROK | After | |
| 1/19/2026 | MID | Lee | Acquired via trade | ROK | After | |
| 1/19/2026 | ROK | Johnson | Acquired via trade | MID | After | |
| 1/19/2026 | ROK | Lee | Traded away | MID | After | |