| Transactions | ||||||
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/7/2000 | GEO | Grieve | Traded away | MAD | After | |
| 3/7/2000 | GEO | Hermanson | Acquired via trade | MAD | After | |
| 3/7/2000 | MAD | Grieve | Acquired via trade | GEO | After | |
| 3/7/2000 | MAD | Hermanson | Traded away | GEO | After | |
| 5/28/2000 | CCL | Loretta | Acquired via trade | GEO | After | |
| 5/28/2000 | CCL | Smith,C | Traded away | GEO | After | |
| 5/28/2000 | GEO | Loretta | Traded away | CCL | After | |
| 5/28/2000 | GEO | Smith,C | Acquired via trade | CCL | After | |
| 5/29/2000 | CCL | Loaiza | Promoted to active roster | Before | ||
| 5/29/2000 | GEO | Hermanson | Demoted to reserve roster | Before | ||
| 6/5/2000 | ROK | Canseco | Demoted to reserve roster | Before | ||
| 6/5/2000 | ROK | Cirillo | Demoted to reserve roster | Before | ||
| 6/5/2000 | ROK | Knoblauch | Demoted to reserve roster | Before | ||
| 8/20/2000 | MAD | Spiezio | Acquired via trade | COP | After | |
| 8/20/2000 | MAD | Veres | Traded away | COP | After | |
| 10/6/2000 | LON | Rusch | Demoted to reserve roster | Before | ||