| Transactions | ||||||
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/12/1986 | CHK | Horner | Acquired via trade | COL | After | |
| 3/12/1986 | CHK | Hume | Traded away | COL | After | |
| 3/12/1986 | COL | Horner | Traded away | CHK | After | |
| 3/12/1986 | COL | Hume | Acquired via trade | CHK | After | |
| 4/15/1986 | BON | Law | Demoted to reserve roster | Before | ||
| 4/15/1986 | BON | Meacham | Promoted to active roster | Before | ||
| 4/15/1986 | BON | Sutcliffe | Demoted to reserve roster | Before | ||
| 5/11/1986 | LON | Browning | Acquired via trade | WIZ | After | |
| 5/11/1986 | LON | Foley | Traded away | WIZ | After | |
| 5/11/1986 | LON | Smith | Acquired via trade | WIZ | After | |
| 5/11/1986 | LON | Valenzuela | Traded away | WIZ | After | |
| 5/11/1986 | WIZ | Browning | Traded away | LON | After | |
| 5/11/1986 | WIZ | Foley | Acquired via trade | LON | After | |
| 5/11/1986 | WIZ | Smith | Traded away | LON | After | |
| 5/11/1986 | WIZ | Valenzuela | Acquired via trade | LON | After | |
| 5/17/1986 | CHK | Pena | Demoted to reserve roster | Before | ||
| 5/26/1986 | COL | Forsch | Traded away | MUL | After | |
| 5/26/1986 | COL | Moseby | Traded away | MUL | After | |
| 5/26/1986 | COL | Rhoden | Acquired via trade | MUL | After | |
| 5/26/1986 | MUL | Forsch | Acquired via trade | COL | After | |
| 5/26/1986 | MUL | Moseby | Acquired via trade | COL | After | |
| 5/26/1986 | MUL | Rhoden | Traded away | COL | After | |
| 5/27/1986 | MUL | Moseby | Promoted to active roster | Before | ||
| 5/27/1986 | Pal | McGee | Demoted to reserve roster | Before | ||
| 5/27/1986 | Pal | McGee | Promoted to active roster | Before | ||
| 5/27/1986 | Pal | Minton | Demoted to reserve roster | Before | ||
| 5/27/1986 | Pal | Minton | Promoted to active roster | Before | ||
| 6/20/1986 | MID | Durham | Acquired via trade | WIZ | After | |
| 6/20/1986 | MID | Grubb | Traded away | WIZ | After | |
| 6/20/1986 | WIZ | Durham | Traded away | MID | After | |
| 6/20/1986 | WIZ | Grubb | Acquired via trade | MID | After | |
| 7/5/1986 | CHK | Candelaria | Traded away | COL | After | |
| 7/5/1986 | CHK | Reuschel | Acquired via trade | COL | After | |
| 7/5/1986 | COL | Candelaria | Acquired via trade | CHK | After | |
| 7/5/1986 | COL | Reuschel | Traded away | CHK | After | |
| 7/6/1986 | COL | Mason | Demoted to reserve roster | Before | ||
| 7/11/1986 | CHK | Reuschel | Promoted to active roster | Before | ||
| 7/25/1986 | TON | Garber | Acquired via trade | WIZ | After | |
| 7/25/1986 | TON | Gossage | Traded away | WIZ | After | |
| 7/25/1986 | TON | Horton | Acquired via trade | WIZ | After | |
| 7/25/1986 | TON | Terrell | Traded away | WIZ | After | |
| 7/25/1986 | WIZ | Garber | Traded away | TON | After | |
| 7/25/1986 | WIZ | Gossage | Acquired via trade | TON | After | |
| 7/25/1986 | WIZ | Horton | Traded away | TON | After | |
| 7/25/1986 | WIZ | Terrell | Acquired via trade | TON | After | |
| 7/26/1986 | COP | Nelson | Demoted to reserve roster | Before | ||
| 8/10/1986 | CRH | Riles | Demoted to reserve roster | Before | ||