| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/6/2020 | BB | Madrigal | Traded away | ACS | | After |
| 4/6/2020 | HS | Chavis | Demoted to reserve roster | | | Before |
| 4/6/2020 | HS | Keller,M | Demoted to reserve roster | | | Before |
| 4/6/2020 | HS | Ramirez,Jo | Demoted to reserve roster | | | Before |
| 4/6/2020 | MSB | Cain | Demoted to reserve roster | | | Before |
| 4/6/2020 | MSB | Dean | Demoted to reserve roster | | | Before |
| 4/6/2020 | MSB | Knizner | Demoted to reserve roster | | | Before |
| 4/6/2020 | MSB | Nola,Au | Demoted to reserve roster | | | Before |
| 4/6/2020 | TB | Anderson,Bre | Demoted to reserve roster | | | Before |
| 4/6/2020 | TB | Chirinos,Y | Demoted to reserve roster | | | Before |
| 4/6/2020 | TB | Happ,I | Demoted to reserve roster | | | Before |
| 4/6/2020 | TB | Puig | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Arozarena | Signed | | | Before |
| 4/10/2020 | MSB | Arozarena | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Cain | Promoted to active roster | | | Before |
| 4/10/2020 | MSB | Kim | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Knizner | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Knizner | Promoted to active roster | | | Before |
| 4/10/2020 | MSB | Liberatore | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Montero | Demoted to reserve roster | | | Before |
| 4/10/2020 | MSB | Nola,Au | Promoted to active roster | | | Before |
| 4/10/2020 | MSB | Webb,T | Signed | | | Before |
| 4/10/2020 | ShS | Dietrich | Promoted to active roster | | | Before |
| 4/10/2020 | ShS | Tanaka | Demoted to reserve roster | | | Before |
| 4/16/2020 | VD | Gott | Acquired via trade | BC | | After |
| 4/16/2020 | VD | Kiermaier | Traded away | BC | | After |
| 4/17/2020 | VD | Gott | Promoted to active roster | | | Before |
| 4/17/2020 | VD | McKay,B | Demoted to reserve roster | | | Before |
| 4/26/2020 | ShS | Diaz,I | Acquired via trade | VD | | After |
| 4/26/2020 | ShS | Yarbrough | Traded away | VD | | After |
| 4/26/2020 | VD | Diaz,I | Traded away | ShS | | After |
| 4/26/2020 | VD | Yarbrough | Acquired via trade | ShS | | After |
| 4/27/2020 | ShS | Teheran | Promoted to active roster | | | Before |
| 4/27/2020 | VD | Heaney | Demoted to reserve roster | | | Before |
| 5/2/2020 | BB | Mazara | Demoted to reserve roster | | | Before |
| 5/2/2020 | BB | Quantrill | Promoted to active roster | | | Before |
| 5/5/2020 | MSB | Cain | Demoted to reserve roster | | | Before |
| 5/5/2020 | MSB | Hernandez | Demoted to reserve roster | | | Before |
| 5/5/2020 | MSB | Profar | Demoted to reserve roster | | | Before |
| 5/5/2020 | MSB | Rosario,A | Demoted to reserve roster | | | Before |
| 5/12/2020 | BB | Clevinger | Traded away | PL | | After |
| 5/12/2020 | BB | Lux | Acquired via trade | PL | | After |
| 5/12/2020 | BB | Pearson | Acquired via trade | PL | | After |
| 5/12/2020 | ShS | Alcantara,S | Traded away | SFR | | After |
| 5/12/2020 | ShS | Rendon | Traded away | SFR | | After |
| 5/12/2020 | ShS | Stanton | Acquired via trade | SFR | | After |
| 5/12/2020 | ShS | Urshela | Acquired via trade | SFR | | After |
| 5/13/2020 | ShS | Tanaka | Promoted to active roster | | | Before |
| 5/15/2020 | BB | Mazara | Promoted to active roster | | | Before |
| 5/15/2020 | ShS | Jansen,K | Acquired via trade | BTB | | After |
| 5/15/2020 | ShS | Senzel | Acquired via trade | BTB | | After |
| 5/15/2020 | ShS | Urshela | Traded away | BTB | | After |
| 5/19/2020 | End | Benintendi | Demoted to reserve roster | | | Before |
| 5/19/2020 | End | Urias,J | Promoted to active roster | | | Before |
| 5/23/2020 | End | Dahl | Acquired via trade | ShS | | After |
| 5/23/2020 | End | Tramell | Traded away | ShS | | After |
| 5/23/2020 | ShS | Dahl | Traded away | End | | After |
| 5/23/2020 | ShS | Tramell | Acquired via trade | End | | After |
| 5/24/2020 | ShS | Marisnick | Traded away | PL | | After |
| 5/24/2020 | ShS | Richards,T | Acquired via trade | PL | | After |
| 5/27/2020 | End | Osuna,R | Demoted to reserve roster | | | Before |
| 5/27/2020 | ShS | Fiers | Traded away | BTB | | After |
| 5/27/2020 | ShS | Keuchel | Acquired via trade | BTB | | After |
| 5/28/2020 | ShS | Keuchel | Promoted to active roster | | | Before |
| 6/3/2020 | End | Osuna,R | Traded away | PL | | After |
| 6/16/2020 | VD | Heaney | Promoted to active roster | | | Before |
| 6/16/2020 | VD | Lucchesi | Demoted to reserve roster | | | Before |
| 6/27/2020 | End | Urias,J | Demoted to reserve roster | | | Before |
| 7/2/2020 | End | Benintendi | Promoted to active roster | | | Before |
| 7/5/2020 | VD | Heaney | Demoted to reserve roster | | | Before |
| 7/5/2020 | VD | Lucchesi | Promoted to active roster | | | Before |
| 7/17/2020 | End | Benintendi | Traded away | PL | | After |
| 7/17/2020 | End | Rizzo | Acquired via trade | PL | | After |
| 7/17/2020 | End | Urias,J | Traded away | PL | | After |
| 7/17/2020 | End | Young | Acquired via trade | PL | | After |
| 7/17/2020 | VD | Petit | Acquired via trade | SFR | | After |
| 7/18/2020 | End | Young | Promoted to active roster | | | Before |
| 7/18/2020 | VD | Chatwood | Demoted to reserve roster | | | Before |
| 7/18/2020 | VD | Petit | Promoted to active roster | | | Before |
| 7/19/2020 | End | Brantley | Acquired via trade | PL | | After |
| 7/19/2020 | End | Grisham | Traded away | PL | | After |
| 7/20/2020 | BB | Bass | Traded away | PL | | After |
| 7/20/2020 | BB | Bedrosian | Acquired via trade | PL | | After |
| 7/21/2020 | End | Schwarber | Demoted to reserve roster | | | Before |
| 7/22/2020 | BB | Bedrosian | Promoted to active roster | | | Before |
| 7/26/2020 | End | Robles,V | Traded away | WN | | After |
| 7/26/2020 | End | Verlander | Acquired via trade | WN | | After |
| 7/27/2020 | BB | Akiyama | Acquired via trade | HS | | After |
| 7/27/2020 | BB | deGrom | Traded away | HS | | After |
| 7/27/2020 | BB | Keller,M | Acquired via trade | HS | | After |
| 7/27/2020 | BB | Sogard | Traded away | HS | | After |
| 7/27/2020 | BB | Torres,G | Acquired via trade | HS | | After |
| 7/27/2020 | BB | Urquidy | Acquired via trade | HS | | After |
| 7/27/2020 | HS | Akiyama | Traded away | BB | | After |
| 7/27/2020 | HS | deGrom | Acquired via trade | BB | | After |
| 7/27/2020 | HS | Keller,M | Traded away | BB | | After |
| 7/27/2020 | HS | Sogard | Acquired via trade | BB | | After |
| 7/27/2020 | HS | Torres,G | Traded away | BB | | After |
| 7/27/2020 | HS | Urquidy | Traded away | BB | | After |
| 7/28/2020 | HS | Biggio | Demoted to reserve roster | | | Before |
| 7/29/2020 | BB | Gonzalez,G | Traded away | VD | | After |
| 7/29/2020 | BB | Heaney | Acquired via trade | VD | | After |
| 7/29/2020 | BB | Newcomb | Acquired via trade | VD | | After |
| 7/29/2020 | BB | Robles,H | Traded away | VD | | After |
| 7/29/2020 | MSB | Bauer | Traded away | VD | | After |
| 7/29/2020 | MSB | McKay,B | Acquired via trade | VD | | After |
| 7/29/2020 | MSB | Moncada | Traded away | VD | | After |
| 7/29/2020 | MSB | Tucker,K | Acquired via trade | VD | | After |
| 7/29/2020 | MSB | Verdugo | Acquired via trade | VD | | After |
| 7/29/2020 | VD | Bauer | Acquired via trade | MSB | | After |
| 7/29/2020 | VD | Fried | Traded away | ACS | | After |
| 7/29/2020 | VD | Gonzalez,G | Acquired via trade | BB | | After |
| 7/29/2020 | VD | Heaney | Traded away | BB | | After |
| 7/29/2020 | VD | Marquez | Acquired via trade | ACS | | After |
| 7/29/2020 | VD | McKay,B | Traded away | MSB | | After |
| 7/29/2020 | VD | Moncada | Acquired via trade | MSB | | After |
| 7/29/2020 | VD | Newcomb | Traded away | BB | | After |
| 7/29/2020 | VD | Robles,H | Acquired via trade | BB | | After |
| 7/29/2020 | VD | Tucker,K | Traded away | MSB | | After |
| 7/29/2020 | VD | Verdugo | Traded away | MSB | | After |
| 7/29/2020 | VD | Voth | Acquired via trade | ACS | | After |
| 7/31/2020 | BB | Heaney | Promoted to active roster | | | Before |
| 7/31/2020 | End | Brantley | Promoted to active roster | | | Before |
| 7/31/2020 | End | Dahl | Demoted to reserve roster | | | Before |
| 7/31/2020 | VD | Lucchesi | Demoted to reserve roster | | | Before |
| 7/31/2020 | VD | Miley | Demoted to reserve roster | | | Before |
| 8/7/2020 | VD | Bauer | Demoted to reserve roster | | | Before |
| 8/7/2020 | VD | Lucchesi | Promoted to active roster | | | Before |
| 8/7/2020 | VD | Marquez | Demoted to reserve roster | | | Before |
| 8/19/2020 | End | Dahl | Promoted to active roster | | | Before |
| 8/19/2020 | End | Riley | Demoted to reserve roster | | | Before |
| 8/21/2020 | End | Dahl | Demoted to reserve roster | | | Before |
| 8/21/2020 | End | Riley | Promoted to active roster | | | Before |
| 8/21/2020 | VD | Bauer | Promoted to active roster | | | Before |
| 8/21/2020 | VD | Lucchesi | Demoted to reserve roster | | | Before |
| 8/21/2020 | VD | Marquez | Promoted to active roster | | | Before |
| 8/21/2020 | VD | Snell | Demoted to reserve roster | | | Before |
| 8/31/2020 | VD | Bauer | Demoted to reserve roster | | | Before |
| 8/31/2020 | VD | Lucchesi | Promoted to active roster | | | Before |
| 8/31/2020 | VD | Marquez | Demoted to reserve roster | | | Before |
| 8/31/2020 | VD | Snell | Promoted to active roster | | | Before |
| 9/3/2020 | VD | Bauer | Promoted to active roster | | | Before |
| 9/3/2020 | VD | Lucchesi | Demoted to reserve roster | | | Before |
| 9/3/2020 | VD | Marquez | Promoted to active roster | | | Before |
| 9/3/2020 | VD | Snell | Demoted to reserve roster | | | Before |
| 9/12/2020 | VD | Bauer | Demoted to reserve roster | | | Before |
| 9/12/2020 | VD | Marquez | Demoted to reserve roster | | | Before |
| 9/12/2020 | VD | Miley | Promoted to active roster | | | Before |
| 9/12/2020 | VD | Snell | Promoted to active roster | | | Before |
| 9/23/2020 | End | Brantley | Demoted to reserve roster | | | Before |
| 9/23/2020 | End | Schwarber | Promoted to active roster | | | Before |
| 10/22/2020 | End | Brantley | Promoted to active roster | | | Before |
| 10/22/2020 | End | Dahl | Promoted to active roster | | | Before |
| 10/22/2020 | End | Pence | Demoted to reserve roster | | | Before |
| 10/22/2020 | End | Syndergaard | Demoted to reserve roster | | | Before |
| 10/22/2020 | VD | Bauer | Promoted to active roster | | | Before |